GO:0050795

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Name regulation of behavior
Categary Process
Go Slim No
Go Link GO:0050795
Unique Molecular Interactions 299
Total Molecular Interactions 391
Total Single Events 3717
Pain Genes Associated 8

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for regulation of behavior. They are ordered first by their pain relevance and then by number of times they were reported for regulation of behavior. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT221180 Binding of OPRM1 and Flna 1 0.09 0.22 12.65
2 INT134284 Binding of OPRM1 and PLD2 1 0.52 0 3.72
3 INT322411 Hist1h1t Positive_regulation of Positive_regulation of OPRM1 1 0.00 1.25 3.63
4 INT18026 Binding of Oprd1 and Oprm1 4 0.40 0.83 3.53
5 INT195931 Binding of OPRM1 and Trpv1 1 0.07 0.87 3.43
6 INT318474 Positive_regulation of OPRM1 Positive_regulation of Localization of CA2 1 0.17 0.55 2.7
7 INT96461 Pnoc Positive_regulation of Oprm1 1 0.09 0.73 2.34
8 INT88730 Binding of OPRM1 and Mop3 1 0.00 0 2.34
9 INT322410 Hist1h1t Positive_regulation of Phosphorylation of OPRM1 1 0.00 0.08 2.31
10 INT134583 Arrb2 Regulation of Oprm1 1 0.41 1.23 2.15
11 INT318473 Positive_regulation of OPRM1 Positive_regulation of CA2 1 0.17 0.46 2.13
12 INT51198 Positive_regulation of Binding of OPRM1 and PDYN 2 0.18 0.3 2.08
13 INT51199 Binding of OPRM1 and PDYN 2 0.13 0.3 2.08
14 INT64750 Binding of Oprm1 and Pck1 2 0.41 0.51 2.07
15 INT107738 Binding of Pld2 and Oprm1 1 0.23 0 1.93
16 INT113572 Binding of DMRT1 and OPRM1 1 0.01 0 1.9
17 INT29996 Binding of Oprm1 and Penk 2 0.36 0.4 1.85
18 INT167319 Binding of OPRM1 and PCSK2 1 0.22 0.63 1.77
19 INT167320 Binding of CPE and OPRM1 1 0.14 0.63 1.77
20 INT167321 Binding of ENG and OPRM1 1 0.27 0.63 1.76
21 INT157524 Binding of GRM5 and OPRM1 1 0.36 0 1.74
22 INT96296 Oprm1 Negative_regulation of Npr1 2 0.05 0.32 1.65
23 INT134742 Binding of OPRM1 and SV2A 1 0.33 0.18 1.64
24 INT135516 PRKCA Negative_regulation of Phosphorylation of OPRM1 1 0.12 0 1.62
25 INT109525 Binding of DMRT1 and Oprm1 1 0.08 0 1.62
26 INT195930 OPRM1 Regulation of Prkaca 1 0.01 0 1.59
27 INT221182 Negative_regulation of Binding of OPRM1 and Flna 1 0.07 0 1.57
28 INT116093 OPRM1 Positive_regulation of Positive_regulation of NFKB1 1 0.36 0.08 1.56
29 INT41100 Mdk Positive_regulation of Localization of INS 1 0.01 0 1.55
30 INT41101 Mdk Negative_regulation of SST 1 0.02 0 1.53
31 INT72666 Binding of ODT and Oprm1 1 0.03 0.53 1.5
32 INT161870 OPRM1 Positive_regulation of Prkcg 1 0.01 0.12 1.47
33 INT141673 Oprm1 Positive_regulation of Negative_regulation of Ltp 1 0.13 0 1.46
34 INT141676 OPRM1 Positive_regulation of Ltp 1 0.04 0 1.46
35 INT141674 Oprm1 Positive_regulation of Ltp 1 0.13 0 1.46
36 INT141675 OPRM1 Positive_regulation of Negative_regulation of Ltp 1 0.04 0 1.46
37 INT131039 Binding of Oprm1 and Prf1 1 0.17 0 1.45
38 INT131041 Negative_regulation of Binding of Oprm1 and Prf1 1 0.21 0 1.45
39 INT131040 Binding of Oprm1 and S100a9 1 0.24 0 1.45
40 INT161858 OPRM1 Positive_regulation of GRIN1 1 0.50 0.12 1.45
41 INT128915 PENK Regulation of Gene_expression of OPRM1 1 0.22 0.07 1.43
42 INT96796 ITIH4 Regulation of Gene_expression of OPRM1 2 0.20 0.89 1.41
43 INT128914 COMT Regulation of OPRM1 1 0.39 0.07 1.39
44 INT51203 Binding of OPRK1 and OPRM1 2 0.29 0.3 1.36
45 INT160590 CSF2 Positive_regulation of Gene_expression of OPRM1 1 0.16 0.54 1.35
46 INT139987 Oprm1 Positive_regulation of Localization of Oprl1 1 0.16 0.17 1.35
47 INT160586 IL6 Positive_regulation of Gene_expression of OPRM1 1 0.14 0.54 1.35
48 INT160588 TNF Positive_regulation of Gene_expression of OPRM1 1 0.20 0.54 1.35
49 INT160587 IFNG Positive_regulation of Gene_expression of OPRM1 1 0.18 0.54 1.35
50 INT160585 IL18 Positive_regulation of Gene_expression of OPRM1 1 0.09 0.54 1.35
51 INT160589 IL4 Positive_regulation of Gene_expression of OPRM1 1 0.13 0.54 1.35
52 INT51200 Binding of OPRM1 and PENK 2 0.17 0.23 1.31
53 INT128310 Oprm1 Positive_regulation of Oprm1 1 0.00 0.1 1.29
54 INT89943 Binding of Oprm1 and Il2 1 0.03 0.53 1.28
55 INT195929 Binding of OPRM1 and Prkaca 1 0.02 0.33 1.27
56 INT64749 Negative_regulation of Binding of Oprm1 and Pck1 1 0.47 0.21 1.27
57 INT110542 SIGMAR1 Regulation of OPRM1 1 0.04 0.33 1.25
58 INT110543 SIGMAR1 Regulation of Gene_expression of OPRM1 1 0.04 0.33 1.25
59 INT126801 Regulation of Binding of Oprm1 and Penk 1 0.34 0.4 1.25
60 INT167278 Binding of OPRM1 and REST 1 0.08 0.94 1.24
61 INT76165 IGKV2-30 Positive_regulation of Phosphorylation of Oprm1 1 0.00 0.08 1.22
62 INT76163 Prkaca Positive_regulation of Phosphorylation of Oprm1 1 0.02 0.08 1.22
63 INT113242 TNF Regulation of Transcription of OPRM1 2 0.45 1.53 1.19
64 INT133496 Binding of Oprm1 and Cckbr 1 0.15 0 1.19
65 INT49955 OPRM1 Positive_regulation of ADCY1 1 0.21 0.31 1.19
66 INT49956 OPRM1 Positive_regulation of SGCG 1 0.53 0.3 1.18
67 INT137144 ITIH4 Regulation of OPRM1 1 0.20 1.13 1.16
68 INT125696 Binding of OPRM1 and SNRNP70 1 0.06 0.99 1.15
69 INT221183 Binding of OPRM1 and Mors1 1 0.00 0 1.12
70 INT113540 Binding of OPRM1 and Tac1 1 0.04 0.1 1.1
71 INT127133 Positive_regulation of OPRM1 Positive_regulation of Protein_catabolism of SUCLG2 1 0.20 0.2 1.1
72 INT90145 Binding of OPRL1 and OPRM1 2 0.27 0.31 1.08
73 INT77982 Binding of YY1 and Oprm1 2 0.17 0.17 1.06
74 INT73311 Binding of Oprm1 and Pdpn 1 0.08 0.71 1.06
75 INT97013 Negative_regulation of Binding of CALM3 and OPRM1 1 0.40 0 1.05
76 INT97011 Binding of CALM3 and OPRM1 1 0.35 0 1.05
77 INT133075 TFAM Positive_regulation of Transcription of OPRM1 1 0.03 0 1.04
78 INT133072 GATA3 Positive_regulation of Transcription of OPRM1 1 0.35 0 1.04
79 INT51204 Positive_regulation of Binding of OPRK1 and OPRM1 1 0.38 0.3 1.03
80 INT70105 SCD Positive_regulation of Oprm1 1 0.01 0 1
81 INT1415 Binding of OPRM1 and POMC 3 0.16 0.3 0.98
82 INT94989 Arrb2 Regulation of Regulation of Oprm1 1 0.24 0 0.98
83 INT51201 Negative_regulation of Binding of OPRM1 and PENK 1 0.20 0.23 0.98
84 INT57555 Binding of Oprm1 and Oprl1 2 0.06 0.05 0.97
85 INT157522 GRM5 Regulation of Gene_expression of OPRM1 1 0.28 0 0.97
86 INT40287 OPRM1 Positive_regulation of Negative_regulation of Prl 1 0.00 0.93 0.96
87 INT83415 Binding of Oprm1 and Ntrk1 1 0.01 0 0.96
88 INT133076 STAT6 Positive_regulation of OPRM1 1 0.38 0 0.95
89 INT152388 Binding of NFKB1 and OPRM1 1 0.04 0.14 0.94
90 INT152390 Negative_regulation of Binding of JUN and OPRM1 1 0.13 0.14 0.94
91 INT152387 Binding of JUN and OPRM1 1 0.15 0.14 0.94
92 INT152389 Negative_regulation of Binding of NFKB1 and OPRM1 1 0.05 0.14 0.94
93 INT128860 NR1H4 Negative_regulation of Gene_expression of OPRM1 1 0.15 0.31 0.92
94 INT79123 Binding of Pnoc and Oprm1 3 0.14 0 0.91
95 INT89314 Binding of CRYGS and OPRM1 1 0.07 0.08 0.91
96 INT113946 Binding of FLNA and OPRM1 1 0.10 0.37 0.9
97 INT128859 Positive_regulation of RXRA Regulation of Gene_expression of OPRM1 1 0.05 0.26 0.9
98 INT61046 Oprm1 Positive_regulation of Gh1 1 0.21 0 0.89
99 INT83417 Binding of OPRL1 and Oprm1 1 0.01 0 0.89
100 INT97184 Oprm1 Regulation of Gene_expression of Pomc 1 0.31 0 0.89
101 INT61047 Oprm1 Positive_regulation of Localization of Gh1 1 0.29 0 0.89
102 INT61048 Oprm1 Positive_regulation of Localization of Prl 1 0.16 0 0.88
103 INT103611 Mdk Negative_regulation of Phosphorylation of Sp1 1 0.01 0.28 0.88
104 INT61045 Oprm1 Positive_regulation of Prl 1 0.16 0 0.88
105 INT112153 Regulation of Binding of Oprm1 and Rtcd1 1 0.00 0.09 0.87
106 INT97738 Mdk Positive_regulation of Mapk3 1 0.08 0.66 0.87
107 INT63859 Oprm1 Negative_regulation of Oprm1 1 0.10 0.08 0.86
108 INT63858 Oprm1 Negative_regulation of Penk 1 0.05 0.08 0.86
109 INT120999 Binding of Oprm1 and Ifng 1 0.22 0.57 0.84
110 INT97012 Binding of CALM1 and OPRM1 1 0.18 0 0.82
111 INT77393 Binding of ARRB1 and OPRM1 1 0.15 0 0.82
112 INT89529 OPRM1 Regulation of CALM1 1 0.27 0 0.81
113 INT112154 Binding of Oprm1 and Rtcd1 1 0.00 0.09 0.81
114 INT90143 Negative_regulation of Binding of OPRL1 and OPRM1 1 0.31 0.07 0.8
115 INT151807 Binding of NFATC1 and OPRM1 1 0.19 0 0.79
116 INT55923 Penk Regulation of Transcription of Oprm1 1 0.26 0 0.78
117 INT55922 Penk Regulation of Oprm1 1 0.26 0 0.78
118 INT121647 Binding of Oprm1 and Atrn 1 0.01 0.12 0.77
119 INT133074 CNR2 Positive_regulation of Transcription of OPRM1 1 0.11 0 0.77
120 INT151808 NFATC1 Positive_regulation of Positive_regulation of OPRM1 1 0.20 0 0.76
121 INT96795 ITIH4 Positive_regulation of Gene_expression of OPRM1 1 0.49 0.17 0.76
122 INT128861 LBR Positive_regulation of Positive_regulation of OPRM1 1 0.19 0.36 0.75
123 INT124404 Binding of POMC and Oprm1 1 0.00 0.25 0.75
124 INT151810 JUND Positive_regulation of Positive_regulation of OPRM1 1 0.26 0 0.74
125 INT151809 JUN Positive_regulation of Positive_regulation of OPRM1 1 0.32 0 0.74
126 INT133070 Positive_regulation of CNR2 Positive_regulation of Transcription of OPRM1 1 0.11 0 0.74
127 INT151806 TRAF3IP2 Positive_regulation of Positive_regulation of OPRM1 1 0.06 0 0.74
128 INT157541 Binding of YY1 and Regulation of Gene_expression of OPRM1 1 0.31 1.21 0.72
129 INT137139 ITIH4 Positive_regulation of OPRM1 1 0.37 0.67 0.72
130 INT157539 Binding of SP1 and Regulation of Gene_expression of OPRM1 1 0.36 1.2 0.72
131 INT162162 ARF6 Regulation of OPRM1 1 0.19 0 0.71
132 INT82759 Binding of IGHG3 and OPRM1 2 0.06 0 0.7
133 INT107741 Binding of OPRM1 and Pld2 1 0.01 0 0.69
134 INT71595 Camk2a Regulation of Negative_regulation of Oprm1 1 0.04 0 0.69
135 INT130717 Binding of OPRM1 and Positive_regulation of Localization of CCL2 1 0.00 0.72 0.68
136 INT86638 POMC Negative_regulation of Gene_expression of OPRM1 1 0.34 0.33 0.68
137 INT30503 OPRM1 Regulation of Localization of Prl 1 0.00 0 0.67
138 INT169215 Binding of OPRM1 and CARTPT 1 0.00 0.22 0.67
139 INT169219 Binding of OPRM1 and Coc 1 0.01 0.22 0.67
140 INT137140 HIVEP1 Regulation of Gene_expression of OPRM1 1 0.25 0.69 0.66
141 INT121812 IL6 Regulation of OPRM1 1 0.22 0.27 0.65
142 INT101716 JUND Regulation of Regulation of OPRM1 1 0.09 0.06 0.65
143 INT322385 PPBP Negative_regulation of Positive_regulation of OPRM1 1 0.00 0 0.64
144 INT137145 HIVEP1 Regulation of OPRM1 1 0.10 0.7 0.64
145 INT122823 ERCC2 Regulation of Negative_regulation of OPRM1 1 0.23 0.17 0.63
146 INT160880 Pld2 Positive_regulation of Oprm1 1 0.07 0.08 0.63
147 INT160882 Pld2 Positive_regulation of Gene_expression of Oprm1 1 0.06 0.08 0.63
148 INT30502 Negative_regulation of OPRM1 Negative_regulation of Gh 1 0.00 0 0.63
149 INT281091 Prkacb Positive_regulation of Mdk 1 0.02 0 0.62
150 INT281076 Adcy1 Positive_regulation of Mdk 1 0.07 0 0.62
151 INT166387 Binding of Gnb2l1 and Mdk 1 0.30 0.24 0.61
152 INT74395 Htr2b Negative_regulation of Pdyn 1 0.03 0 0.61
153 INT101718 PLAT Positive_regulation of Transcription of OPRM1 1 0.22 0.06 0.61
154 INT281086 Prkaca Positive_regulation of Mdk 1 0.08 0 0.61
155 INT113962 OPRM1 Regulation of CREB1 1 0.39 0.31 0.6
156 INT126951 PNOC Positive_regulation of OPRM1 1 0.21 0.06 0.6
157 INT6723 Negative_regulation of Pomc Positive_regulation of Positive_regulation of Oprm1 1 0.20 0.55 0.6
158 INT64776 Binding of Oprm1 and Kcnj3 1 0.38 0 0.6
159 INT117707 Oprm1 Positive_regulation of PIK3CG 1 0.00 0.08 0.6
160 INT137138 ITIH4 Positive_regulation of Positive_regulation of OPRM1 1 0.42 0.55 0.59
161 INT123009 Oprm1 Positive_regulation of Localization of OR6K2 1 0.00 0 0.59
162 INT144864 Htr2b Positive_regulation of Localization of Gh1 1 0.48 0 0.58
163 INT50434 Binding of Oprm1 and Mop3 1 0.00 0 0.58
164 INT121813 IL6 Positive_regulation of OPRM1 1 0.28 0.28 0.58
165 INT159125 Binding of OPRM1 and SUGT1 1 0.03 0.31 0.57
166 INT210830 OPRM1 Negative_regulation of ADCY1 1 0.00 0.06 0.55
167 INT99486 OPRM1 Positive_regulation of MAPK3 1 0.22 0 0.55
168 INT168128 Oprm1 Regulation of Mir190 1 0.11 0 0.54
169 INT49225 Mdk Regulation of Tac1 1 0.00 0 0.53
170 INT137143 HIVEP1 Positive_regulation of OPRM1 1 0.15 0.43 0.52
171 INT113241 TRAF3IP2 Regulation of Transcription of OPRM1 1 0.05 0.82 0.52
172 INT126654 Oprd1 Regulation of Oprm1 1 0.03 0.13 0.52
173 INT113243 TNF Positive_regulation of Transcription of OPRM1 1 0.23 0.84 0.51
174 INT318472 CA2 Regulation of OPRM1 1 0.17 0 0.51
175 INT144456 Binding of GPM6A and OPRM1 1 0.07 0 0.5
176 INT115800 Positive_regulation of HRASLS Positive_regulation of Positive_regulation of OPRM1 1 0.11 0 0.49
177 INT31818 Negative_regulation of Binding of Sst and Oprm1 1 0.26 0.3 0.48
178 INT31817 Positive_regulation of Binding of Sst and Oprm1 1 0.30 0.3 0.48
179 INT160881 Positive_regulation of Oprm1 Positive_regulation of Positive_regulation of Pld2 1 0.05 0.08 0.48
180 INT150536 OPRM1 Positive_regulation of Positive_regulation of IL6 1 0.04 0.38 0.48
181 INT31816 Binding of Sst and Oprm1 1 0.22 0.3 0.48
182 INT150537 OPRM1 Positive_regulation of Negative_regulation of IL6 1 0.04 0.38 0.48
183 INT150539 OPRM1 Positive_regulation of IL6 1 0.04 0.38 0.48
184 INT83690 Binding of Oprm1 and Ptprg 1 0.00 0.08 0.48
185 INT150534 OPRM1 Positive_regulation of TNF 1 0.03 0.38 0.48
186 INT150535 OPRM1 Positive_regulation of Positive_regulation of TNF 1 0.08 0.38 0.48
187 INT26338 Binding of OPRM1 and Prl 1 0.02 0.37 0.47
188 INT89647 OPRM1 Regulation of ADCY1 1 0.09 0.09 0.47
189 INT281982 Cyp3a23/3a1 Negative_regulation of Gene_expression of MDK 1 0.00 0.67 0.47
190 INT64217 Oprm1 Positive_regulation of Oprd1 1 0.24 0 0.46
191 INT127400 Negative_regulation of Mdk Negative_regulation of Gene_expression of Elk1 1 0.01 0.71 0.45
192 INT127399 Negative_regulation of Mdk Negative_regulation of Positive_regulation of Nfkb1 1 0.02 0.7 0.45
193 INT127398 Negative_regulation of Mdk Negative_regulation of Gene_expression of Tacr1 1 0.01 0.71 0.45
194 INT127397 Negative_regulation of Mdk Negative_regulation of Gene_expression of Grin1 1 0.01 0.71 0.45
195 INT127396 Negative_regulation of Mdk Negative_regulation of Gene_expression of Grin2a 1 0.00 0.71 0.45
196 INT73055 Binding of Oprm1 and Ncr1 1 0.07 0.32 0.45
197 INT46008 OPRM1 Regulation of Localization of PRL 1 0.14 0 0.44
198 INT127401 Negative_regulation of Mdk Negative_regulation of Phosphorylation of Elk1 1 0.01 0.7 0.44
199 INT139487 Oprm1 Positive_regulation of Th 1 0.26 0.1 0.42
200 INT33006 Oprm1 Regulation of Localization of LH 1 0.03 0 0.42

Single Events

The table below shows the top 100 pain related interactions that have been reported for regulation of behavior. They are ordered first by their pain relevance and then by number of times they were reported in regulation of behavior. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT11624 Gene_expression of OPRM1 445 0.78 72.36 294.36
2 INT6293 Gene_expression of Oprm1 312 0.78 48.73 215.61
3 INT5930 Positive_regulation of Oprm1 221 0.70 31.19 172.93
4 INT4768 Positive_regulation of OPRM1 212 0.70 31.09 164.28
5 INT6042 Binding of Oprm1 248 0.48 31.77 154.34
6 INT4658 Binding of OPRM1 188 0.48 25.96 136.24
7 INT5931 Regulation of Oprm1 149 0.62 18.15 125.93
8 INT5906 Negative_regulation of Oprm1 125 0.59 19.58 101.57
9 INT1639 Negative_regulation of OPRM1 107 0.59 13.86 90.37
10 INT7528 Regulation of OPRM1 100 0.62 20.63 80.57
11 INT49747 Transcription of Oprm1 68 0.72 9.01 53.78
12 INT69484 Positive_regulation of Gene_expression of OPRM1 75 0.70 12.86 52.27
13 INT1564 Localization of OPRM1 41 0.80 8.03 44.67
14 INT14137 Localization of Oprm1 56 0.81 2.88 36.09
15 INT77407 Regulation of Gene_expression of OPRM1 51 0.62 12.58 35.75
16 INT70437 Negative_regulation of Mdk 115 0.57 41.03 35.72
17 INT48907 Positive_regulation of Gene_expression of Oprm1 53 0.69 8.55 33.52
18 INT69483 Transcription of OPRM1 45 0.72 7.31 30.22
19 INT49431 Phosphorylation of OPRM1 31 0.82 2.2 29.09
20 INT6294 Regulation of Gene_expression of Oprm1 28 0.62 6.77 22.79
21 INT21105 Phosphorylation of Oprm1 32 0.82 0.83 19.29
22 INT58495 Positive_regulation of Positive_regulation of Oprm1 22 0.49 2.44 17.66
23 INT6043 Negative_regulation of Binding of Oprm1 24 0.57 2.67 16.78
24 INT32753 Positive_regulation of Positive_regulation of OPRM1 19 0.62 3.3 16.73
25 INT98647 Positive_regulation of Mdk 65 0.59 32.93 15.67
26 INT76863 Negative_regulation of Gene_expression of OPRM1 21 0.57 6.56 13.69
27 INT80883 Positive_regulation of Phosphorylation of OPRM1 13 0.69 1.03 13.65
28 INT68814 Positive_regulation of Transcription of Oprm1 16 0.60 2.72 13.57
29 INT20066 Gene_expression of Mdk 38 0.76 21.41 13.4
30 INT6044 Regulation of Binding of Oprm1 16 0.61 3.01 11.11
31 INT59766 Positive_regulation of Negative_regulation of Oprm1 9 0.50 1.31 11.08
32 INT71592 Negative_regulation of Gene_expression of Oprm1 11 0.58 4.03 10.37
33 INT49483 Regulation of Positive_regulation of Oprm1 8 0.61 2.34 9.4
34 INT33209 Positive_regulation of Binding of OPRM1 8 0.68 0.63 8.95
35 INT76162 Positive_regulation of Phosphorylation of Oprm1 11 0.69 0.64 8.72
36 INT18021 Positive_regulation of Binding of Oprm1 16 0.70 2.53 8.38
37 INT31060 Negative_regulation of Binding of OPRM1 12 0.37 2.65 7.75
38 INT101721 Positive_regulation of Transcription of OPRM1 8 0.48 1.22 7.74
39 INT121815 Regulation of Positive_regulation of OPRM1 7 0.62 0.75 7.36
40 INT16628 Negative_regulation of Positive_regulation of Oprm1 9 0.43 0.89 6.92
41 INT245173 Gene_expression of MDK 81 0.49 51.08 6.78
42 INT5932 Regulation of Regulation of Oprm1 7 0.61 0.44 6.47
43 INT42832 Negative_regulation of Positive_regulation of OPRM1 6 0.36 0.96 6.35
44 INT97600 Regulation of Transcription of OPRM1 8 0.52 1.14 6.21
45 INT53135 Positive_regulation of Localization of Oprm1 2 0.50 0 6.12
46 INT27118 Regulation of Binding of OPRM1 10 0.62 1.18 5.97
47 INT36921 Regulation of Mdk 14 0.26 6.49 5.8
48 INT110545 Regulation of Regulation of OPRM1 7 0.42 1.68 5.67
49 INT85075 Phosphorylation of Mdk 22 0.61 10.29 5.55
50 INT32979 Positive_regulation of Localization of OPRM1 5 0.50 0 5.54
51 INT42833 Positive_regulation of Negative_regulation of OPRM1 6 0.48 0.12 4.95
52 INT28983 Regulation of Htr2b 3 0.22 0.26 3.96
53 INT80882 Negative_regulation of Phosphorylation of OPRM1 4 0.45 0.21 3.68
54 INT5929 Positive_regulation of Regulation of Oprm1 4 0.50 0.56 3.48
55 INT13347 Regulation of Negative_regulation of OPRM1 5 0.45 0.64 3.38
56 INT41099 Localization of Mdk 5 0.64 2.38 2.89
57 INT70377 Regulation of Transcription of Oprm1 3 0.47 0.93 2.78
58 INT281978 Regulation of MDK 1 0.30 5.9 2.66
59 INT36923 Binding of Mdk 7 0.35 3.81 2.58
60 INT36920 Positive_regulation of Gene_expression of Mdk 8 0.49 2.03 2.53
61 INT64062 Negative_regulation of Regulation of OPRM1 2 0.41 0.3 2.48
62 INT71952 Regulation of Negative_regulation of Oprm1 3 0.43 0.09 2.18
63 INT190644 Regulation of Negative_regulation of Mdk 6 0.26 2.49 1.98
64 INT32980 Positive_regulation of Regulation of OPRM1 2 0.45 0 1.98
65 INT142684 Protein_catabolism of OPRM1 2 0.66 0.48 1.81
66 INT131572 Negative_regulation of Phosphorylation of Mdk 4 0.15 1.67 1.71
67 INT245172 Positive_regulation of Gene_expression of MDK 19 0.43 12.97 1.65
68 INT161217 Positive_regulation of Htr2b 1 0.67 2.55 1.58
69 INT98648 Negative_regulation of Positive_regulation of Mdk 5 0.50 3.03 1.56
70 INT130552 Negative_regulation of Localization of Oprm1 2 0.31 0.37 1.53
71 INT21106 Regulation of Phosphorylation of Oprm1 3 0.61 0 1.43
72 INT115804 Regulation of Localization of OPRM1 2 0.33 0.12 1.33
73 INT85667 Negative_regulation of Negative_regulation of Oprm1 3 0.37 0.54 1.31
74 INT135665 Negative_regulation of Negative_regulation of Mdk 3 0.27 0.76 1.28
75 INT223121 Positive_regulation of Positive_regulation of Mdk 6 0.20 2.7 1.27
76 INT67450 Negative_regulation of Localization of OPRM1 2 0.06 0.24 1.26
77 INT14138 Regulation of Localization of Oprm1 1 0.28 0 1.23
78 INT245174 Positive_regulation of MDK 4 0.30 5.05 1.17
79 INT161216 Positive_regulation of Gene_expression of Htr2b 1 0.49 1.87 1.16
80 INT207610 Positive_regulation of Phosphorylation of Mdk 7 0.26 2.66 1.15
81 INT161219 Gene_expression of Htr2b 4 0.75 2.01 1.14
82 INT281973 Regulation of Gene_expression of MDK 1 0.30 2.52 1.11
83 INT35786 Negative_regulation of Negative_regulation of OPRM1 2 0.33 0.91 1.1
84 INT21108 Negative_regulation of Phosphorylation of Oprm1 2 0.43 0 0.98
85 INT30157 Gene_expression of Htr2b 2 0.48 0 0.94
86 INT281977 Negative_regulation of Gene_expression of MDK 1 0.29 3.05 0.91
87 INT245171 Transcription of MDK 4 0.35 2.61 0.78
88 INT55921 Negative_regulation of Transcription of Oprm1 1 0.43 0 0.76
89 INT174517 Localization of AHI1 2 0.24 1.62 0.68
90 INT95337 Negative_regulation of AHI1 2 0.02 0.75 0.68
91 INT129375 Negative_regulation of Regulation of Oprm1 1 0.28 0.49 0.68
92 INT130891 Regulation of Gene_expression of Mdk 2 0.38 1.38 0.65
93 INT57127 Binding of Htr2b 2 0.36 0.05 0.63
94 INT36922 Positive_regulation of Binding of Mdk 2 0.44 0.09 0.53
95 INT281979 Negative_regulation of MDK 1 0.21 1.4 0.5
96 INT305077 Localization of CRHBP 1 0.76 0.28 0.44
97 INT161218 Positive_regulation of Positive_regulation of Htr2b 1 0.67 0.69 0.43
98 INT76874 Negative_regulation of Htr2b 1 0.07 0 0.41
99 INT190643 Regulation of Positive_regulation of Mdk 1 0.23 0.5 0.4
100 INT275045 Binding of MDK 2 0.15 1.32 0.31
101 INT18041 Protein_catabolism of Oprm1 1 0.87 0 0.31
102 INT247097 Binding of CRHBP 3 0.34 0.4 0.28
103 INT281976 Regulation of Transcription of MDK 1 0.13 0.29 0.26
104 INT291229 Regulation of Phosphorylation of Mdk 1 0.06 0.33 0.26
105 INT57126 Transcription of Htr2b 1 0.33 0 0.24
106 INT281971 Negative_regulation of Negative_regulation of MDK 1 0.18 0.27 0.23
107 INT296875 Positive_regulation of AHI1 2 0.15 3.53 0.16
108 INT76794 Gene_expression of AHI1 3 0.04 1.69 0.14
109 INT351552 Localization of MDK 1 0.47 0 0.11
110 INT76793 Regulation of Gene_expression of AHI1 1 0.00 0.13 0.07
111 INT145889 Positive_regulation of Gene_expression of AHI1 1 0.01 0.47 0.07
112 INT233451 Negative_regulation of Htr2b 1 0.33 0.09 0
113 INT337993 Negative_regulation of Transcription of Mdk 1 0.35 0.82 0
114 INT293719 Negative_regulation of Gene_expression of Mdk 1 0.05 0 0
115 INT337964 Transcription of Mdk 1 0.43 0.82 0
116 INT281761 Protein_catabolism of Mdk 1 0.10 0 0
117 INT347593 Negative_regulation of Gene_expression of Htr2b 1 0.01 0.16 0
118 INT175528 Regulation of Regulation of Mdk 1 0.15 1 0
119 INT293720 Positive_regulation of Negative_regulation of Mdk 1 0.05 0.07 0
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