GO:0050796

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Name regulation of insulin secretion
Categary Process
Go Slim No
Go Link GO:0050796
Unique Molecular Interactions 2960
Total Molecular Interactions 4024
Total Single Events 41081
Pain Genes Associated 71

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for regulation of insulin secretion. They are ordered first by their pain relevance and then by number of times they were reported for regulation of insulin secretion. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT95068 Tlr4 Positive_regulation of IL1B 1 0.03 4.54 5.6
2 INT139706 Tnf Positive_regulation of Ltp 1 0.03 2.61 4.63
3 INT128296 Negative_regulation of IL1B Positive_regulation of Insr 1 0.10 1.36 4.52
4 INT128295 IL1B Positive_regulation of Insr 1 0.11 1.36 4.5
5 INT64718 IL1B Positive_regulation of Gene_expression of IL6 15 0.59 9.37 4.48
6 INT143270 Binding of Cnr1 and Gprasp1 4 0.54 0.64 4.18
7 INT127128 Binding of CNR1 and CNR2 8 0.39 3.98 3.97
8 INT61359 TNF Positive_regulation of NFKB1 11 0.63 6.66 3.89
9 INT57985 Il1b Positive_regulation of Il6 5 0.59 1.66 3.53
10 INT146412 Tnf Positive_regulation of Gene_expression of Trpv1 2 0.66 5.22 3.22
11 INT64719 IL1B Positive_regulation of IL6 7 0.41 6.84 3.14
12 INT150886 Il1a Regulation of Il1b 1 0.02 3.46 2.93
13 INT264929 Binding of Cnr1 and Gnaz 1 0.18 1.71 2.89
14 INT130721 Binding of IL1B and IL1RN 6 0.05 5.29 2.85
15 INT83169 Binding of Cck and Lep 7 0.42 1.58 2.78
16 INT278948 LEP Positive_regulation of Gene_expression of PTGER2 1 0.09 4.04 2.69
17 INT140024 Tnf Positive_regulation of Gene_expression of Il1b 2 0.49 2.75 2.61
18 INT152501 Binding of Tnf and Tnfrsf1a 4 0.31 3 2.58
19 INT104219 SCD Positive_regulation of Cnr1 1 0.00 2.67 2.54
20 INT143271 Binding of Gprasp1 and Positive_regulation of Negative_regulation of Cnr1 1 0.78 0.16 2.53
21 INT151826 Tnf Positive_regulation of TNF 1 0.04 3.38 2.51
22 INT117532 SETBP1 Positive_regulation of Gene_expression of TNF 1 0.54 0.85 2.44
23 INT143272 Binding of CNR1 and Gprasp1 1 0.01 0.17 2.42
24 INT122163 Binding of TNF and TNFRSF1B 6 0.44 6.06 2.41
25 INT61733 Tlr4 Positive_regulation of Gene_expression of Tnf 3 0.26 1.99 2.36
26 INT238914 Positive_regulation of CNR1 Positive_regulation of Phosphorylation of MAPK1 1 0.19 3.22 2.35
27 INT139705 Negative_regulation of Tnf Positive_regulation of Ltp 1 0.03 1.19 2.3
28 INT198958 Cnr1 Positive_regulation of Kcnj9 1 0.00 0.15 2.24
29 INT279361 Binding of TNF and KLF1 4 0.00 3.72 2.19
30 INT94492 Il6 Positive_regulation of Gene_expression of Il1b 1 0.27 3.81 2.19
31 INT94491 Il1b Positive_regulation of Gene_expression of Tnf 1 0.25 3.81 2.19
32 INT94504 Il6 Positive_regulation of Gene_expression of Tnf 1 0.30 3.8 2.19
33 INT94494 Il1b Positive_regulation of Gene_expression of Il6 1 0.27 3.81 2.19
34 INT86179 TNF Positive_regulation of Localization of IL6 5 0.35 1.66 2.17
35 INT209924 IL1B Negative_regulation of PPARA 1 0.20 4.38 2.17
36 INT148704 Binding of TNF and TNFRSF1A 5 0.44 3.3 2.09
37 INT122660 Binding of CACNA1A and DNAH8 2 0.28 2.68 2.08
38 INT196586 Negative_regulation of Mapk14 Negative_regulation of TNF 2 0.04 2.02 2.08
39 INT81295 Ifng Positive_regulation of Gene_expression of Nos2 4 0.39 0.87 2.05
40 INT140032 Tnf Positive_regulation of Gene_expression of Ifng 2 0.43 2.23 2
41 INT140030 Il1b Positive_regulation of Gene_expression of Ifng 2 0.48 2.23 2
42 INT140026 Il1b Positive_regulation of Gene_expression of Tnf 2 0.49 2.23 2
43 INT278937 LEP Positive_regulation of Gene_expression of IL6 1 0.32 3.42 1.97
44 INT83170 Lep Regulation of Cck 5 0.43 0.68 1.96
45 INT217042 IRF6 Positive_regulation of TNF 4 0.27 3.03 1.95
46 INT129212 RYBP Positive_regulation of Tnf 2 0.03 1.9 1.95
47 INT264928 Binding of Cnr1 and Hrh1 1 0.01 1.61 1.92
48 INT279359 Binding of ADA and TNF 1 0.20 2.61 1.91
49 INT51051 IL1B Positive_regulation of Localization of IL6 7 0.57 3.79 1.87
50 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87
51 INT81920 Binding of IL1B and NFKB1 1 0.04 1.54 1.85
52 INT50993 Il1b Positive_regulation of Fos 2 0.40 0.43 1.84
53 INT349658 Nos2 Regulation of Gene_expression of Nos1 1 0.63 2.86 1.84
54 INT199287 TNF Positive_regulation of Transcription of Oprm1 2 0.02 1.86 1.8
55 INT224432 TNF Positive_regulation of Gene_expression of VEGFA 1 0.13 5.83 1.8
56 INT137207 Tnf Positive_regulation of Nfkb1 3 0.23 2.69 1.71
57 INT264922 Binding of Cnr1 and Mors1 1 0.14 0.1 1.71
58 INT167427 Mapk8 Regulation of Regulation of Tnf 1 0.26 2.83 1.7
59 INT89379 TNF Positive_regulation of Gene_expression of IL6 5 0.50 4.37 1.69
60 INT100274 IL1RN Negative_regulation of IL1B 5 0.53 1.79 1.65
61 INT83093 IL1B Positive_regulation of BDKRB1 1 0.51 0.44 1.65
62 INT61134 IL10 Negative_regulation of Gene_expression of IL1B 3 0.46 2.13 1.63
63 INT135516 PRKCA Negative_regulation of Phosphorylation of OPRM1 1 0.12 0 1.62
64 INT79778 Tlr4 Positive_regulation of Localization of TNF 4 0.08 4.21 1.61
65 INT167202 TNF Regulation of Gene_expression of Ngf 1 0.10 1.47 1.6
66 INT209853 TNF Regulation of Gene_expression of CD36 1 0.61 3.41 1.59
67 INT266767 SFTPA1 Positive_regulation of Gene_expression of TNF 1 0.01 1.69 1.59
68 INT118515 Positive_regulation of PRKCA Positive_regulation of Phosphorylation of TRPV1 1 0.27 0.56 1.58
69 INT89011 Lep Positive_regulation of Insr 1 0.19 2.41 1.57
70 INT74937 IL1B Positive_regulation of CPOX 5 0.18 1.13 1.55
71 INT198653 TNF Positive_regulation of MIF 1 0.15 3.81 1.55
72 INT41100 Mdk Positive_regulation of Localization of INS 1 0.01 0 1.55
73 INT252633 Binding of TNF and Tnfrsf1b 4 0.05 3.66 1.54
74 INT91456 IL1B Positive_regulation of Gene_expression of CPOX 6 0.17 3.36 1.53
75 INT167201 Gtf3a Regulation of TNF 1 0.01 1.39 1.52
76 INT158775 Regulation of Tnf Regulation of Ephb1 1 0.18 0.09 1.52
77 INT158777 Tnf Regulation of Ephb1 1 0.18 0.09 1.51
78 INT192081 Igkv11-125 Positive_regulation of Cnr1 1 0.10 0.23 1.51
79 INT10276 Il1b Regulation of Gene_expression of Penk 1 0.61 0.85 1.5
80 INT140029 Ifng Positive_regulation of Gene_expression of Tnf 1 0.43 1.69 1.5
81 INT140028 Ifng Positive_regulation of Gene_expression of Il1b 1 0.48 1.69 1.5
82 INT166676 Binding of PRKCA and UGT1A6 1 0.30 0 1.5
83 INT92057 Ifng Positive_regulation of Gene_expression of Ik 1 0.03 0.45 1.49
84 INT150887 Il1b Regulation of Il10 1 0.04 1.74 1.47
85 INT158776 Il1b Regulation of Ephb1 1 0.15 0.09 1.46
86 INT285569 TNF Negative_regulation of Gene_expression of Il6 1 0.03 2.83 1.46
87 INT72755 Tap1 Negative_regulation of TNF 1 0.43 2.45 1.46
88 INT150069 Cnr1 Regulation of Cnr2 2 0.50 0.83 1.42
89 INT131156 Binding of RUNX1 and TNF 2 0.03 3.44 1.42
90 INT83626 Ifng Positive_regulation of Gene_expression of Cd59 1 0.33 2.19 1.41
91 INT197111 Binding of IL1B and MCF2 1 0.02 2.12 1.4
92 INT108727 Binding of ATP1A2 and CACNA1A 2 0.34 1.97 1.37
93 INT161511 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Il1b 1 0.41 0.27 1.36
94 INT161513 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Tnf 1 0.33 0.27 1.35
95 INT160588 TNF Positive_regulation of Gene_expression of OPRM1 1 0.20 0.54 1.35
96 INT160587 IFNG Positive_regulation of Gene_expression of OPRM1 1 0.18 0.54 1.35
97 INT122659 Binding of CACNA1A and SAR1B 1 0.06 1.38 1.35
98 INT56087 TNF Regulation of Gene_expression of SERPINE1 1 0.43 1.67 1.33
99 INT95093 ITIH4 Positive_regulation of IL1B 1 0.43 1.04 1.32
100 INT95094 Negative_regulation of ITIH4 Positive_regulation of IL1B 1 0.36 1.04 1.32
101 INT355252 Binding of Cacna1a and Cnr1 1 0.04 0 1.31
102 INT198957 Binding of Cnr1 and Mastl 1 0.00 0 1.31
103 INT121705 IL1B Positive_regulation of Gene_expression of MMP3 3 0.49 1.2 1.3
104 INT192080 Foxm1 Positive_regulation of Cnr1 2 0.14 0.72 1.3
105 INT186393 Binding of TNF and Tnfrsf1a 9 0.37 8.55 1.29
106 INT135830 Gch1 Regulation of Nos2 1 0.65 0 1.29
107 INT130333 FUT3 Negative_regulation of Positive_regulation of Tnf 1 0.01 0.36 1.29
108 INT108386 IL1B Positive_regulation of MMP1 3 0.27 1.56 1.28
109 INT169289 CNR1 Positive_regulation of EGFR 1 0.62 0.36 1.28
110 INT121703 IL1B Positive_regulation of Gene_expression of MMP1 3 0.49 1.14 1.27
111 INT34052 POMC Regulation of Gene_expression of IFNG 1 0.11 0 1.27
112 INT70037 TNF Regulation of IL10 2 0.09 2.11 1.26
113 INT296796 Tbrs1 Positive_regulation of Gene_expression of TNF 1 0.00 1.58 1.26
114 INT161507 Tlr4 Positive_regulation of Gene_expression of Il1b 1 0.24 0.19 1.25
115 INT108389 IL1B Positive_regulation of ADAMTS4 1 0.51 1.19 1.24
116 INT197092 TNF Regulation of VEGFA 4 0.21 2.78 1.22
117 INT131807 Bpifa2 Positive_regulation of Localization of Tnf 1 0.32 2.09 1.22
118 INT70035 TNF Regulation of Negative_regulation of PRF1 1 0.05 1.42 1.21
119 INT70039 IL1B Regulation of Negative_regulation of IL10 1 0.07 1.42 1.21
120 INT70032 TNF Regulation of PRF1 1 0.05 1.42 1.21
121 INT70040 TNF Regulation of Negative_regulation of IL10 1 0.09 1.42 1.21
122 INT70038 IL1B Regulation of PRF1 1 0.05 1.42 1.21
123 INT328743 TNF Positive_regulation of Mapk14 1 0.04 1.4 1.21
124 INT70031 IL1B Regulation of Negative_regulation of PRF1 1 0.05 1.42 1.21
125 INT70030 IL1B Regulation of IL10 1 0.07 1.42 1.21
126 INT194861 Binding of IL1B and IL1R1 2 0.01 1.55 1.2
127 INT210982 Binding of Cnr1 and Cfp 2 0.22 1.27 1.2
128 INT209926 IL1B Regulation of PPARA 1 0.21 2.45 1.2
129 INT194619 Il15 Positive_regulation of Gene_expression of TNF 1 0.24 2.23 1.2
130 INT131462 NGF Regulation of Localization of INS 1 0.40 0.97 1.2
131 INT63384 Binding of Cnr1 and Insrr 1 0.03 0.24 1.2
132 INT133046 TNF Positive_regulation of Positive_regulation of NFKB1 5 0.54 3.23 1.19
133 INT113242 TNF Regulation of Transcription of OPRM1 2 0.45 1.53 1.19
134 INT314196 Ngf Positive_regulation of Tnf 1 0.50 1.98 1.18
135 INT238916 CNR1 Positive_regulation of Phosphorylation of MAPK1 1 0.19 1.61 1.17
136 INT289465 IRF6 Positive_regulation of IL1B 3 0.05 0.9 1.16
137 INT253827 Cck Regulation of Cartpt 1 0.41 0 1.16
138 INT212815 WAS Positive_regulation of CNR1 1 0.01 0.62 1.16
139 INT212824 WAS Positive_regulation of Cnr1 1 0.21 0.62 1.16
140 INT94502 Il1b Positive_regulation of Gene_expression of Avp 1 0.28 1.97 1.15
141 INT94509 Il1b Positive_regulation of Gene_expression of AVP 1 0.36 1.96 1.15
142 INT231769 TNF Negative_regulation of Gene_expression of HMOX1 1 0.26 4.75 1.15
143 INT264930 Gnaz Positive_regulation of Negative_regulation of Cnr1 1 0.20 0 1.14
144 INT225104 CNR1 Positive_regulation of Gene_expression of RETNLB 1 0.01 1.41 1.14
145 INT66767 Il1b Positive_regulation of Pla2g10 1 0.05 0.47 1.13
146 INT110671 Binding of Cnr1 and Alox5 1 0.07 0.2 1.13
147 INT94498 Il1b Positive_regulation of Gene_expression of Crh 1 0.24 1.94 1.13
148 INT141979 Calca Negative_regulation of Gene_expression of Il1b 1 0.40 0.62 1.13
149 INT72754 Adamts7 Negative_regulation of TNF 1 0.28 1.64 1.13
150 INT89938 Tlr4 Positive_regulation of Gene_expression of TNF 6 0.25 1.3 1.12
151 INT66907 Il1b Positive_regulation of Localization of Oxt 2 0.78 0.18 1.12
152 INT123454 CNR1 Regulation of Fos 1 0.00 0.06 1.12
153 INT123455 CNR1 Regulation of Positive_regulation of Fos 1 0.00 0.06 1.12
154 INT167428 Il1b Positive_regulation of Localization of Gpt 1 0.43 1.31 1.11
155 INT107264 Binding of TNF and NCR3 1 0.30 1.42 1.1
156 INT139704 Tnf Positive_regulation of Mapk14 1 0.22 0.73 1.1
157 INT107266 Binding of HLA-DRB1 and TNF 1 0.29 1.41 1.1
158 INT122889 Ifng Positive_regulation of Gene_expression of HLA-E 1 0.02 0.97 1.1
159 INT323175 PRKCA Positive_regulation of Akt1 1 0.02 0 1.1
160 INT267597 IL10 Negative_regulation of Gene_expression of TNF 1 0.03 2.24 1.1
161 INT107267 Binding of HLA-A and TNF 1 0.34 1.41 1.1
162 INT57982 Il1b Positive_regulation of Crh 2 0.38 0.98 1.09
163 INT94495 Tnf Positive_regulation of Gene_expression of Il6 1 0.30 1.9 1.09
164 INT107562 Penk Positive_regulation of Localization of Il1b 1 0.20 0.09 1.09
165 INT107561 Mtr Positive_regulation of Localization of Il1b 1 0.04 0.09 1.09
166 INT74939 IL1B Positive_regulation of Gene_expression of HGF 1 0.58 0.72 1.09
167 INT151825 Tnf Positive_regulation of Mapk14 1 0.22 1.72 1.09
168 INT94500 Tnf Positive_regulation of Gene_expression of Il1b 1 0.25 1.9 1.09
169 INT76396 Il10 Negative_regulation of Il1b 2 0.65 1.89 1.08
170 INT107567 Hps4 Positive_regulation of Localization of Il1b 1 0.01 0.09 1.08
171 INT139703 Tnf Positive_regulation of Mapk8 1 0.32 0.73 1.08
172 INT152502 Tnf Negative_regulation of Binding of Tnfrsf1a 1 0.37 0.6 1.08
173 INT119108 Binding of LTBR and TNF 2 0.15 1.47 1.07
174 INT107564 Hps4 Regulation of Localization of Il1b 1 0.01 0.1 1.07
175 INT107560 Penk Regulation of Localization of Il1b 1 0.18 0.1 1.07
176 INT114364 Hmgb1 Positive_regulation of Gene_expression of TNF 2 0.05 1.85 1.06
177 INT57986 Il1b Regulation of Positive_regulation of Il6 2 0.39 0.23 1.05
178 INT120312 Ghrh Regulation of Tnf 1 0.26 0.95 1.05
179 INT120314 Ghrh Regulation of Positive_regulation of Tnf 1 0.43 0.95 1.05
180 INT30905 SST Negative_regulation of Localization of GCG 2 0.12 1.56 1.04
181 INT152504 Binding of CR1 and Tnf 1 0.00 0.49 1.04
182 INT162319 Positive_regulation of F2rl1 Positive_regulation of Il1b 1 0.46 1.6 1.04
183 INT113235 Tacr1 Regulation of Gene_expression of Ifng 1 0.26 1 1.04
184 INT133650 Epo Negative_regulation of TNF 1 0.35 2.7 1.04
185 INT101443 Penk Positive_regulation of Localization of Gcg 1 0.50 1.21 1.04
186 INT65986 IL1B Positive_regulation of PTGS2 3 0.32 2.05 1.03
187 INT88875 Ifng Positive_regulation of Transcription of Nos2 1 0.02 0.27 1.03
188 INT128297 Il1b Positive_regulation of CRH 1 0.02 0.27 1.03
189 INT156245 NFKB1 Positive_regulation of Regulation of TNF 1 0.45 0.76 1.03
190 INT81545 Tnf Positive_regulation of Gtf3a 2 0.03 1.41 1.02
191 INT88887 IRF6 Positive_regulation of Transcription of Nos2 1 0.21 0.27 1.02
192 INT88874 Ifng Regulation of Nos2 1 0.01 0.26 1.01
193 INT271875 IL1RN Negative_regulation of Binding of IL1B 1 0.01 1.3 1.01
194 INT117311 HP Positive_regulation of Lep 1 0.00 1.78 1.01
195 INT88879 Ifng Positive_regulation of Nfkb1 1 0.01 0.26 1.01
196 INT88884 IRF6 Regulation of Nos2 1 0.12 0.26 1
197 INT278962 LEP Positive_regulation of CPOX 1 0.05 1.33 1
198 INT88886 IRF6 Positive_regulation of Nos2 1 0.22 0.26 1
199 INT88888 Regulation of IRF6 Positive_regulation of Nos2 1 0.20 0.26 1
200 INT351443 Cnr1 Regulation of Positive_regulation of Vta1 1 0.12 0.93 0.99

Single Events

The table below shows the top 100 pain related interactions that have been reported for regulation of insulin secretion. They are ordered first by their pain relevance and then by number of times they were reported in regulation of insulin secretion. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82
2 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98
3 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81
4 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68
5 INT6852 Localization of TNF 883 0.81 705.95 270.84
6 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97
7 INT6481 Binding of TNF 624 0.48 510.2 214.82
8 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210
9 INT48955 Gene_expression of Nos2 753 0.78 403.87 208.08
10 INT6488 Gene_expression of Tnf 484 0.78 339.61 191.58
11 INT66280 Gene_expression of Nos2 534 0.78 330.78 157.07
12 INT13353 Positive_regulation of Tnf 332 0.70 248.75 148.1
13 INT812 Localization of INS 1026 0.81 515.6 145.31
14 INT9660 Regulation of TNF 363 0.62 312.94 139.99
15 INT48953 Positive_regulation of Nos2 486 0.70 239.85 131.87
16 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61
17 INT65731 Gene_expression of Cnr1 234 0.78 63.82 109.34
18 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01
19 INT10272 Gene_expression of Il1b 194 0.78 121.02 103.03
20 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9
21 INT69764 Positive_regulation of Cnr1 126 0.70 67.8 91.49
22 INT77435 Positive_regulation of Nos2 343 0.70 208.49 91.43
23 INT74376 Gene_expression of Cnr1 173 0.78 73.43 89.7
24 INT10166 Localization of Tnf 237 0.81 153.95 88.64
25 INT64636 Positive_regulation of Gene_expression of Nos2 242 0.70 147.52 79.53
26 INT15769 Gene_expression of Il1b 146 0.78 114.51 75.35
27 INT5056 Gene_expression of IFNG 216 0.78 137.52 74.57
28 INT10274 Positive_regulation of Il1b 123 0.70 79.76 73.56
29 INT9236 Regulation of Gene_expression of TNF 204 0.62 162.66 72.99
30 INT11380 Negative_regulation of IL1B 215 0.59 125.62 72.35
31 INT10359 Gene_expression of Ifng 159 0.78 79.6 72.14
32 INT58400 Negative_regulation of Tnf 182 0.59 129.97 71
33 INT49995 Positive_regulation of Gene_expression of Tnf 187 0.70 125.07 70.54
34 INT6849 Localization of IL1B 229 0.81 112.56 69.63
35 INT7534 Gene_expression of Ifng 193 0.78 111.02 68.6
36 INT6489 Positive_regulation of Gene_expression of Tnf 140 0.70 92.31 67.85
37 INT65733 Positive_regulation of Cnr1 125 0.70 40.27 67.33
38 INT6486 Positive_regulation of Tnf 168 0.70 123.47 66.05
39 INT6894 Gene_expression of CNR1 168 0.78 74.07 62.84
40 INT52800 Negative_regulation of Gene_expression of Tnf 142 0.59 92.27 55.47
41 INT251 Regulation of INS 398 0.62 232.47 55.04
42 INT48952 Negative_regulation of Nos2 204 0.59 101.73 53.15
43 INT49017 Negative_regulation of Gene_expression of Nos2 169 0.59 80.64 52.67
44 INT22112 Positive_regulation of Localization of TNF 164 0.70 115.66 52.18
45 INT50334 Negative_regulation of Cnr1 84 0.58 30.86 51.75
46 INT62630 Positive_regulation of CNR1 86 0.70 40.34 51.51
47 INT6473 Positive_regulation of Gene_expression of IL1B 204 0.70 117.23 50.86
48 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43
49 INT17881 Gene_expression of LEP 278 0.78 221.61 48.31
50 INT66029 Negative_regulation of Tnf 100 0.59 84.28 48.16
51 INT48718 Positive_regulation of PRKCA 109 0.69 36.16 46.49
52 INT55670 Negative_regulation of Gene_expression of Tnf 83 0.59 57.16 46.33
53 INT1322 Positive_regulation of Localization of INS 293 0.70 120.86 45.98
54 INT63383 Binding of Cnr1 77 0.48 22.28 44.61
55 INT5307 Regulation of Tnf 87 0.62 78.71 43.4
56 INT85943 Negative_regulation of Nos2 161 0.59 108.56 42.65
57 INT13354 Transcription of TNF 108 0.72 85.81 42.32
58 INT9233 Negative_regulation of Gene_expression of IL1B 114 0.59 56.99 41.82
59 INT48075 Positive_regulation of Il1b 71 0.67 48.63 40.48
60 INT5973 Regulation of IL1B 109 0.62 66.6 39.88
61 INT16194 Binding of CNR1 82 0.48 20.75 39.59
62 INT3252 Negative_regulation of INS 428 0.59 271.65 39.52
63 INT77434 Positive_regulation of Gene_expression of Nos2 151 0.69 96.76 38.94
64 INT3253 Negative_regulation of Localization of INS 205 0.59 130.39 36.61
65 INT12608 Regulation of CNR1 62 0.60 24.36 36.02
66 INT53577 Negative_regulation of Localization of TNF 110 0.59 59.28 35.23
67 INT6484 Binding of IL1B 122 0.47 75.84 35.07
68 INT79060 Gene_expression of NOS2 116 0.78 69.25 34.84
69 INT2274 Regulation of Localization of INS 101 0.62 41.55 34.79
70 INT66005 Regulation of Cnr1 47 0.61 19.21 34.52
71 INT50308 Binding of Cnr1 61 0.48 14.41 33.52
72 INT92837 Negative_regulation of Gene_expression of Nos2 116 0.59 59.67 31.82
73 INT35406 Localization of Tnf 94 0.81 64.63 31.65
74 INT9347 Localization of Il1b 58 0.81 26.13 31.53
75 INT1473 Localization of Gcg 95 0.80 17.35 30.31
76 INT52712 Negative_regulation of PRKCA 64 0.57 23.11 28.43
77 INT57692 Positive_regulation of Gene_expression of Il1b 50 0.67 43.54 28.29
78 INT111359 Localization of Cnr1 55 0.81 11.25 27.41
79 INT75418 Negative_regulation of Cnr1 41 0.59 14.65 27.28
80 INT52801 Regulation of Gene_expression of Tnf 55 0.62 48.74 26.59
81 INT10273 Positive_regulation of Gene_expression of Il1b 47 0.68 31.15 26.21
82 INT61953 Transcription of Nos2 101 0.72 46.64 25.49
83 INT5948 Regulation of Il1b 44 0.60 22.8 25.4
84 INT101483 Gene_expression of Lep 159 0.78 104.77 25.12
85 INT56224 Negative_regulation of Gene_expression of Ifng 40 0.58 23.34 25.08
86 INT17625 Localization of GCG 210 0.80 55.69 24.97
87 INT43486 Positive_regulation of Ifng 52 0.69 32.71 24.77
88 INT74377 Regulation of Cnr1 38 0.59 16.93 24.77
89 INT10349 Negative_regulation of Il1b 48 0.58 25.53 24.24
90 INT8518 Localization of Ifng 53 0.81 36.68 24.13
91 INT89854 Regulation of Nos2 49 0.61 42.58 24.1
92 INT70503 Regulation of Gene_expression of Nos2 71 0.62 44 24.01
93 INT79061 Positive_regulation of NOS2 92 0.65 58.89 23.96
94 INT51029 Negative_regulation of Il1b 34 0.57 29.34 23.62
95 INT5055 Positive_regulation of IFNG 89 0.69 64.03 23.05
96 INT76123 Gene_expression of Lep 193 0.78 94.17 22.76
97 INT48081 Localization of Il1b 46 0.80 21.59 22.4
98 INT66753 Negative_regulation of Positive_regulation of Tnf 45 0.59 35.28 22.33
99 INT8483 Positive_regulation of Positive_regulation of TNF 73 0.67 60.35 22.03
100 INT53575 Regulation of Gene_expression of Tnf 46 0.62 34.35 20.63
101 INT79805 Phosphorylation of PRKCA 57 0.81 23.33 20.41
102 INT66281 Transcription of Nos2 81 0.71 39.49 20.37
103 INT9237 Regulation of Gene_expression of IL1B 49 0.62 30.69 20.34
104 INT82434 Positive_regulation of LEP 117 0.70 95.45 20.22
105 INT10442 Negative_regulation of CNR1 47 0.59 20.88 20.2
106 INT53574 Regulation of Tnf 45 0.62 40.68 19.71
107 INT25222 Positive_regulation of Gene_expression of Ifng 32 0.50 24.18 19.58
108 INT66751 Negative_regulation of Localization of Tnf 48 0.59 26 19.36
109 INT66755 Transcription of Tnf 45 0.72 37.1 19.11
110 INT79955 Localization of Cnr1 26 0.81 8.44 19.06
111 INT19509 Localization of Ifng 55 0.78 28.25 18.67
112 INT35086 Positive_regulation of Gene_expression of Ifng 40 0.69 22.55 18.35
113 INT36054 Transcription of IL1B 53 0.72 32.64 17.31
114 INT24209 Negative_regulation of Ifng 37 0.57 16.52 17.15
115 INT10169 Positive_regulation of Localization of Tnf 44 0.70 27.71 16.75
116 INT61949 Regulation of Nos2 74 0.58 34.08 16.7
117 INT19929 Negative_regulation of Positive_regulation of TNF 52 0.59 38.16 16.51
118 INT87932 Positive_regulation of Gene_expression of Cnr1 28 0.69 8.86 16.38
119 INT77433 Regulation of Gene_expression of Nos2 49 0.62 35.07 16.33
120 INT62629 Localization of CNR1 35 0.76 11.86 16.3
121 INT49986 Transcription of Tnf 25 0.72 18.3 16.22
122 INT25223 Positive_regulation of Gene_expression of IFNG 41 0.67 36.97 15.89
123 INT62681 Negative_regulation of LEP 93 0.59 66.97 15.77
124 INT61172 Gene_expression of PRKCA 34 0.77 8.89 15.47
125 INT75908 Regulation of LEP 77 0.60 60.16 15.19
126 INT10360 Positive_regulation of Ifng 33 0.68 21.73 15.19
127 INT12087 Regulation of Localization of TNF 44 0.62 28.71 15.17
128 INT25266 Positive_regulation of Localization of IL1B 38 0.69 15.89 14.35
129 INT10173 Binding of Tnf 45 0.48 35.6 14.32
130 INT64048 Positive_regulation of Positive_regulation of Tnf 32 0.70 21.24 13.74
131 INT29170 Negative_regulation of Gene_expression of Il1b 25 0.59 16.36 13.68
132 INT52714 Regulation of PRKCA 28 0.61 7.73 13.66
133 INT74375 Positive_regulation of Gene_expression of Cnr1 24 0.70 14.25 13.66
134 INT4931 Localization of IFNG 53 0.78 33.25 13.65
135 INT19191 Negative_regulation of Localization of IL1B 35 0.58 15.19 13.63
136 INT14572 Binding of INS 205 0.48 175.43 13.38
137 INT6478 Negative_regulation of Binding of TNF 36 0.58 30.42 13.31
138 INT6575 Positive_regulation of Localization of Gcg 33 0.69 3.48 13.31
139 INT7532 Negative_regulation of Gene_expression of Ifng 33 0.59 18.56 13.14
140 INT8210 Positive_regulation of Gene_expression of INS 188 0.68 146.57 12.83
141 INT89404 Regulation of Negative_regulation of TNF 30 0.45 24.47 12.71
142 INT58226 Negative_regulation of Gene_expression of Il1b 24 0.57 18.09 12.68
143 INT73641 Regulation of Lep 45 0.62 26.2 12.59
144 INT51028 Regulation of Il1b 28 0.60 21.15 12.47
145 INT69763 Positive_regulation of Positive_regulation of Cnr1 12 0.50 9.05 12.46
146 INT5057 Negative_regulation of Gene_expression of IFNG 23 0.58 8.33 12.3
147 INT13409 Gene_expression of NEUROD1 52 0.75 14.17 12.23
148 INT9160 Negative_regulation of Ifng 31 0.58 16.37 11.84
149 INT2586 Positive_regulation of Gcg 35 0.70 9.25 11.75
150 INT97381 Negative_regulation of Positive_regulation of Nos2 34 0.59 16.66 11.6
151 INT82984 Gene_expression of Cartpt 27 0.78 3.93 11.55
152 INT72221 Localization of PRKCA 17 0.81 1.23 11.47
153 INT95369 Positive_regulation of Gene_expression of NOS2 36 0.55 25.09 11.37
154 INT126743 Positive_regulation of Gene_expression of LEP 61 0.66 50.02 11.17
155 INT48956 Negative_regulation of Positive_regulation of Nos2 34 0.46 13.15 11.15
156 INT82079 Positive_regulation of Lep 79 0.70 40 11.07
157 INT19944 Negative_regulation of IFNG 39 0.58 22.35 10.91
158 INT4605 Negative_regulation of Gene_expression of INS 220 0.58 139.66 10.75
159 INT51265 Phosphorylation of TNF 32 0.81 25.33 10.75
160 INT60434 Negative_regulation of Positive_regulation of Tnf 20 0.46 10.01 10.64
161 INT50196 Transcription of Il1b 25 0.69 19.08 10.43
162 INT101481 Positive_regulation of Lep 81 0.69 62.59 9.95
163 INT106565 Negative_regulation of Gene_expression of Cnr1 19 0.59 6.98 9.93
164 INT8740 Localization of Gcg 65 0.78 19 9.81
165 INT80110 Regulation of Positive_regulation of TNF 34 0.44 25.79 9.78
166 INT4494 Regulation of GCG 41 0.45 18.38 9.68
167 INT70850 Positive_regulation of Transcription of Nos2 30 0.70 18.95 9.68
168 INT48078 Regulation of Gene_expression of Il1b 15 0.62 14.78 9.53
169 INT26492 Negative_regulation of Localization of GCG 73 0.58 22.2 9.48
170 INT82078 Negative_regulation of Lep 54 0.59 20.47 9.38
171 INT6019 Positive_regulation of NEUROD1 37 0.67 17.3 8.89
172 INT48860 Regulation of Localization of Tnf 25 0.61 20.68 8.78
173 INT68267 Gene_expression of CACNA1A 22 0.75 11.39 8.65
174 INT3658 Regulation of Gcg 28 0.53 12.89 8.58
175 INT82082 Localization of Lep 63 0.81 26.41 8.56
176 INT53573 Negative_regulation of Localization of Tnf 19 0.59 11.57 8.54
177 INT75907 Binding of LEP 53 0.46 46.65 8.44
178 INT15529 Gene_expression of GCG 51 0.75 18.55 8.35
179 INT116605 Binding of Nos2 28 0.37 16.88 8.18
180 INT72337 Positive_regulation of Positive_regulation of Nos2 37 0.65 17.02 8.11
181 INT2257 Localization of Gip 31 0.74 11.08 7.92
182 INT86411 Negative_regulation of Negative_regulation of TNF 24 0.42 17.6 7.89
183 INT214106 Gene_expression of Cartpt 21 0.73 3.68 7.84
184 INT10444 Positive_regulation of Gene_expression of CNR1 18 0.69 8.69 7.84
185 INT66926 Transcription of Il1b 15 0.69 13.16 7.81
186 INT112191 Positive_regulation of Transcription of Nos2 22 0.66 12.4 7.74
187 INT85751 Positive_regulation of Positive_regulation of Nos2 40 0.60 23.53 7.72
188 INT48077 Positive_regulation of Localization of Il1b 17 0.69 8.8 7.68
189 INT50195 Positive_regulation of Positive_regulation of Il1b 12 0.67 7.41 7.64
190 INT2587 Regulation of Localization of Gcg 22 0.60 1.73 7.59
191 INT49490 Positive_regulation of Transcription of TNF 19 0.70 14.76 7.58
192 INT4606 Regulation of Gene_expression of INS 67 0.61 54.69 7.53
193 INT87976 Regulation of Gene_expression of Cnr1 9 0.58 6.87 7.51
194 INT68299 Binding of Tnf 17 0.39 12.55 7.49
195 INT75526 Positive_regulation of Positive_regulation of PRKCA 16 0.50 4.34 7.46
196 INT3659 Negative_regulation of Gcg 26 0.51 10.08 7.39
197 INT11378 Negative_regulation of Positive_regulation of IL1B 23 0.59 10.28 7.26
198 INT66752 Positive_regulation of Transcription of Tnf 15 0.68 10.86 7.26
199 INT86898 Negative_regulation of Gene_expression of Cnr1 13 0.55 3.33 7.25
200 INT5326 Regulation of Ifng 12 0.55 4.56 7.19
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