GO:0050808

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Name synapse organization
Categary Process
Go Slim No
Go Link GO:0050808
Unique Molecular Interactions 112
Total Molecular Interactions 130
Total Single Events 1284
Pain Genes Associated 16

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for synapse organization. They are ordered first by their pain relevance and then by number of times they were reported for synapse organization. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT105716 Vta1 Regulation of Nfasc 1 0.14 0 1.89
2 INT152835 Prkcg Regulation of Phosphorylation of Nfasc 1 0.10 0.21 0.87
3 INT134027 Olr696 Regulation of Drp2 1 0.01 0.15 0.68
4 INT194914 Mtx1 Regulation of Gene_expression of Nfasc 1 0.00 0.71 0.58
5 INT335594 Myo5a Regulation of Hmmr 1 0.00 0.39 0.45
6 INT300609 Binding of Ctnnb1 and Wnt2 1 0.02 0.25 0.37
7 INT152240 Nfasc Regulation of Gene_expression of Nos2 1 0.06 0.19 0.36
8 INT124378 Prodh2 Positive_regulation of Ctnnb1 1 0.00 0.59 0.35
9 INT237633 Cntn1 Regulation of Gene_expression of Ank3 1 0.00 0.23 0.33
10 INT237637 Cntn1 Positive_regulation of Gene_expression of Ank3 1 0.00 0.23 0.33
11 INT237640 Nfasc Regulation of Gene_expression of Ank3 1 0.01 0.23 0.32
12 INT237634 Nfasc Positive_regulation of Gene_expression of Ank3 1 0.02 0.23 0.32
13 INT237635 Cntn1 Regulation of Nfasc 1 0.04 0.22 0.3
14 INT237638 Cntn1 Positive_regulation of Nfasc 1 0.07 0.22 0.3
15 INT237641 Binding of Cntnap1 and Nfasc 2 0.36 0.1 0.29
16 INT237643 Binding of Cntn1 and Nfasc 1 0.06 0.05 0.21
17 INT57964 Myo5a Regulation of Negative_regulation of Cyp1a1 1 0.00 0.1 0.2
18 INT237642 Binding of Ank3 and Nfasc 1 0.02 0 0.2
19 INT237639 Binding of Nfasc and Gnptab 1 0.01 0 0.2
20 INT265048 INCENP Positive_regulation of Positive_regulation of Nfasc 1 0.00 0.69 0.19
21 INT202508 Gpbar1 Positive_regulation of Positive_regulation of Nfasc 1 0.00 0.57 0.19
22 INT130932 Negative_regulation of Cpox Positive_regulation of Gene_expression of TSC1 1 0.00 0.42 0.18
23 INT273792 Cxcr2 Positive_regulation of Nfasc 1 0.08 0.29 0.17
24 INT252901 PTTG1 Regulation of Gene_expression of TSC1 1 0.00 1.61 0.13
25 INT251115 Positive_regulation of Binding of AR and Ctnnb1 1 0.01 1.02 0.13
26 INT251114 Binding of AR and Ctnnb1 1 0.01 1 0.12
27 INT191759 NFASC Negative_regulation of ELANE 1 0.00 0.98 0.11
28 INT74014 Binding of TSC1 and XRCC1 1 0.02 1.98 0.09
29 INT273791 Ntf3 Positive_regulation of Nfasc 1 0.01 0.18 0.09
30 INT276304 PRDM1 Regulation of TSC1 1 0.01 1.29 0.09
31 INT276391 Prdm1 Regulation of TSC1 1 0.00 1.29 0.09
32 INT202505 Binding of Cd40lg and Positive_regulation of Positive_regulation of Nfasc 1 0.09 0.45 0.08
33 INT254491 Positive_regulation of Binding of Cntnap1 and Nfasc 1 0.02 0.1 0.08
34 INT272012 Binding of TSC1 and Lsamp 1 0.03 2.1 0.08
35 INT10986 Nfasc Regulation of Hal 1 0.00 0.07 0.07
36 INT272003 Binding of Tsc2 and Tsc1 1 0.18 1.1 0.07
37 INT57965 Myo5a Negative_regulation of Cyp2e1 1 0.01 0.09 0.07
38 INT202506 Psmb8 Positive_regulation of Nfasc 1 0.01 0.59 0.06
39 INT191756 NFASC Positive_regulation of Gene_expression of IGKV1D-39 1 0.00 0.11 0.06
40 INT246793 Binding of Tsc2 and Tsc1 1 0.04 0.71 0.04
41 INT191760 NFASC Positive_regulation of Localization of MPO 1 0.00 0.55 0.04
42 INT302159 TSC1 Positive_regulation of Transcription of CDKN1A 1 0.00 0.28 0.03
43 INT272603 Binding of Dlg4 and Nlgn2 1 0.23 0 0.03
44 INT272009 Binding of YWHAQ and Tsc1 1 0.37 0.14 0.03
45 INT272604 Binding of Dlg4 and Nlgn3 1 0.17 0 0.03
46 INT278210 Binding of Ciita and Nfasc 1 0.04 0.07 0.03
47 INT341537 F2RL1 Positive_regulation of TSC1 1 0.01 0.76 0.03
48 INT246640 GAST Positive_regulation of NFASC 1 0.00 1.26 0.03
49 INT343744 mn Negative_regulation of Regulation of Wnt7a 1 0.01 0.1 0
50 INT180164 Gast Positive_regulation of Nfasc 1 0.02 1.31 0
51 INT355603 Binding of CTNNA1 and Ctnnb1 1 0.00 1.07 0
52 INT246808 Tsc2 Regulation of Regulation of Tsc1 1 0.02 0.05 0
53 INT220818 Binding of Ctnnb1 and Myc 1 0.06 0.13 0
54 INT240420 Myo5a Positive_regulation of CD4 1 0.06 0.27 0
55 INT286566 Binding of Ctnnb1 and Cdh6 1 0.00 1 0
56 INT271990 Tsc1 Positive_regulation of Tsc2 1 0.36 0.31 0
57 INT272018 Binding of TSC1 and Tsc2 1 0.17 0.48 0
58 INT286562 Gene_expression of Pkd1 Positive_regulation of Ctnnb1 1 0.02 0.52 0
59 INT331222 Tsc1 Negative_regulation of Mtor 1 0.00 0.68 0
60 INT271996 Binding of Plk1 and Tsc1 1 0.09 0.32 0
61 INT136693 Gtf3a Positive_regulation of Ctnnb1 1 0.05 0 0
62 INT297614 ZNF275 Positive_regulation of Gene_expression of TSC1 1 0.00 1.56 0
63 INT202507 Nfasc Positive_regulation of Gene_expression of Bcl2 1 0.10 0.7 0
64 INT271991 Tsc1 Regulation of Tsc2 1 0.23 0.15 0
65 INT272015 Pkd1 Positive_regulation of Localization of TSC1 1 0.18 0.65 0
66 INT287885 Binding of DVL1 and AXIN1 1 0.02 0 0
67 INT272017 TBC1D7 Positive_regulation of Protein_catabolism of Tsc1 1 0.08 0.46 0
68 INT297613 Negative_regulation of ZNF275 Positive_regulation of Gene_expression of TSC1 1 0.00 1.66 0
69 INT259093 Binding of TSC1 and LMO4 1 0.02 0.74 0
70 INT240723 Atp2b2 Positive_regulation of Localization of Ca2 1 0.11 0.43 0
71 INT217786 TSC1 Regulation of MITF 1 0.00 1.27 0
72 INT351157 TSC1 Positive_regulation of Gene_expression of CAV1 1 0.01 1.43 0
73 INT271985 Tsc1 Regulation of Cdkn1b 1 0.04 0.1 0
74 INT259092 TSC1 Positive_regulation of Gene_expression of TCEAL1 1 0.01 4.58 0
75 INT268596 Mir10a Regulation of TSC1 1 0.01 0.44 0
76 INT220821 Binding of MAX and Ctnnb1 1 0.09 0.13 0
77 INT272008 Tsc1 Negative_regulation of Binding of HERC1 1 0.01 0.32 0
78 INT297615 Binding of TSC1 and HDAC9 1 0.01 0.4 0
79 INT300337 Gene_expression of MITF Negative_regulation of Gene_expression of TSC1 1 0.00 0.65 0
80 INT240724 Atp2b2 Positive_regulation of Ca2 1 0.11 0.54 0
81 INT217784 Binding of MITF and TSC1 1 0.00 1.21 0
82 INT272014 Binding of RB1CC1 and Tsc1 1 0.05 0.44 0
83 INT286561 Binding of Ctnnb1 and Cdh2 1 0.00 1.06 0
84 INT331223 Negative_regulation of Tsc1 Positive_regulation of Positive_regulation of Mtor 1 0.01 0.33 0
85 INT286567 Prkd1 Regulation of Ctnnb1 1 0.01 0.39 0
86 INT217774 TP53 Regulation of TSC1 1 0.02 1.28 0
87 INT217791 TP53 Positive_regulation of TSC1 1 0.04 0.61 0
88 INT300631 Binding of TSC1 and TSC2 1 0.15 2.59 0
89 INT271998 Cdk1 Positive_regulation of Phosphorylation of Tsc1 1 0.17 0.3 0
90 INT286572 Binding of Ctnnb1 and Pkd1 1 0.02 0.96 0
91 INT268509 MIR146B Regulation of TSC1 1 0.03 0.44 0
92 INT131787 Binding of Myo5a and Pon1 1 0.02 0.06 0
93 INT271986 Tsc1 Regulation of Skp2 1 0.13 0.14 0
94 INT331221 Binding of Akt1 and Tsc1 1 0.03 0.33 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for synapse organization. They are ordered first by their pain relevance and then by number of times they were reported in synapse organization. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT167856 Gene_expression of Nfasc 74 0.71 39.29 23.64
2 INT8634 Gene_expression of Nfasc 23 0.68 9.16 14.96
3 INT180163 Positive_regulation of Nfasc 49 0.40 31.96 9.41
4 INT8632 Regulation of Nfasc 15 0.54 2.87 9.08
5 INT8633 Negative_regulation of Gene_expression of Nfasc 1 0.51 0.6 8.79
6 INT53487 Gene_expression of TSC1 81 0.58 77.71 7.94
7 INT194905 Positive_regulation of Gene_expression of Nfasc 16 0.10 11.87 6.19
8 INT8631 Negative_regulation of Nfasc 12 0.42 3.33 5.71
9 INT114993 Binding of Myo5a 15 0.30 11.46 5.48
10 INT61366 Positive_regulation of NFASC 16 0.26 13.75 4.11
11 INT108579 Localization of Nfasc 18 0.72 3.47 4
12 INT86280 Positive_regulation of Nfasc 14 0.62 6.56 3.84
13 INT194913 Localization of Nfasc 17 0.36 9.91 3.76
14 INT73463 Positive_regulation of Gene_expression of TSC1 20 0.38 14.59 3.53
15 INT160251 Gene_expression of Myo5a 48 0.63 37.14 3.16
16 INT194898 Regulation of Gene_expression of Nfasc 1 0.03 4.51 2.93
17 INT101567 Gene_expression of Ctnnb1 7 0.64 10.11 2.89
18 INT94085 Binding of NFASC 10 0.17 7.1 2.5
19 INT180161 Binding of Nfasc 23 0.48 10.92 2.4
20 INT194893 Positive_regulation of Positive_regulation of Nfasc 7 0.27 6.19 2.35
21 INT55090 Positive_regulation of Wnt7a 13 0.37 2.25 2.2
22 INT194895 Negative_regulation of Nfasc 22 0.37 9.94 1.98
23 INT81641 Gene_expression of Ctnnb1 23 0.72 14.93 1.97
24 INT90826 Localization of NFASC 8 0.17 6.01 1.97
25 INT194907 Transcription of Nfasc 1 0.05 3.25 1.94
26 INT56925 Negative_regulation of TSC1 54 0.52 63.39 1.87
27 INT123990 Positive_regulation of Ctnnb1 8 0.43 2.85 1.63
28 INT99391 Localization of Ctnnb1 7 0.80 5.84 1.61
29 INT94083 Gene_expression of NFASC 8 0.19 4.19 1.52
30 INT107969 Negative_regulation of NFASC 6 0.24 2.58 1.44
31 INT311241 Transcription of Myo5a 1 0.50 1.61 1.37
32 INT214073 Binding of TSC1 9 0.37 22 1.34
33 INT99389 Negative_regulation of Ctnnb1 8 0.45 3.97 1.21
34 INT104170 Phosphorylation of Nfasc 4 0.34 1.38 1.2
35 INT94080 Negative_regulation of Binding of NFASC 2 0.14 1.36 1.18
36 INT194901 Regulation of Nfasc 8 0.21 5.76 1.15
37 INT101570 Positive_regulation of Gene_expression of Ctnnb1 1 0.58 5.7 1.07
38 INT194909 Positive_regulation of Transcription of Nfasc 1 0.04 1.82 1.05
39 INT194891 Negative_regulation of Gene_expression of Nfasc 4 0.37 1.99 1.02
40 INT127647 Regulation of Wnt7a 3 0.07 1.28 1.01
41 INT130793 Positive_regulation of Gene_expression of Nfasc 1 0.02 1.76 0.99
42 INT151906 Positive_regulation of Positive_regulation of Nfasc 2 0.11 1.98 0.98
43 INT73465 Transcription of TSC1 4 0.07 3.47 0.96
44 INT55647 Binding of Nfasc 5 0.35 5.43 0.94
45 INT192785 Regulation of Myo5a 4 0.05 9.05 0.93
46 INT194904 Negative_regulation of Localization of Nfasc 1 0.03 1.62 0.91
47 INT101566 Negative_regulation of Gene_expression of Ctnnb1 1 0.35 2.28 0.88
48 INT287954 Gene_expression of DVL1 8 0.24 2.48 0.83
49 INT74019 Regulation of TSC1 27 0.35 23.61 0.79
50 INT57958 Positive_regulation of Myo5a 9 0.41 7.52 0.77
51 INT87758 Negative_regulation of Regulation of Nfasc 1 0.42 0 0.75
52 INT82117 Phosphorylation of NFASC 2 0.46 1.82 0.72
53 INT134023 Regulation of Drp2 1 0.34 0.15 0.68
54 INT194911 Negative_regulation of Positive_regulation of Nfasc 5 0.23 3.33 0.67
55 INT28958 Negative_regulation of Wnt7a 3 0.45 0.49 0.65
56 INT99390 Regulation of Ctnnb1 4 0.62 3.12 0.64
57 INT61365 Regulation of NFASC 3 0.21 1.85 0.58
58 INT127648 Gene_expression of Wnt7a 2 0.13 1.11 0.56
59 INT76960 Negative_regulation of Ctnnb1 5 0.57 3.46 0.53
60 INT104168 Protein_catabolism of Nfasc 4 0.89 1.31 0.52
61 INT194906 Negative_regulation of Transcription of Nfasc 1 0.03 0.95 0.48
62 INT81645 Positive_regulation of Gene_expression of Ctnnb1 6 0.63 3.78 0.47
63 INT271939 Regulation of Tsc1 2 0.41 1.16 0.47
64 INT175423 Positive_regulation of TSC1 25 0.36 21.81 0.45
65 INT53282 Negative_regulation of Atp2b2 4 0.15 2.6 0.45
66 INT76958 Positive_regulation of Ctnnb1 14 0.64 5.48 0.41
67 INT95872 Localization of Ctnnb1 7 0.74 2.75 0.4
68 INT237625 Gene_expression of Ank3 2 0.53 0.38 0.4
69 INT115194 Negative_regulation of Positive_regulation of NFASC 1 0.14 0 0.38
70 INT81644 Regulation of Ctnnb1 5 0.41 3.38 0.37
71 INT81643 Regulation of Gene_expression of Ctnnb1 3 0.57 1.5 0.37
72 INT195574 Localization of Myo5a 4 0.34 1.1 0.36
73 INT194890 Positive_regulation of Localization of Nfasc 2 0.10 0.96 0.34
74 INT202067 Protein_catabolism of NFASC 1 0.04 0.79 0.34
75 INT184803 Localization of TSC1 5 0.37 6.13 0.32
76 INT108324 Negative_regulation of Gene_expression of Ctnnb1 1 0.06 1.43 0.31
77 INT256540 Regulation of Gene_expression of TSC1 4 0.07 4.74 0.3
78 INT287931 Positive_regulation of Gene_expression of DVL1 2 0.09 0.08 0.29
79 INT202488 Regulation of Positive_regulation of Nfasc 3 0.11 1.45 0.26
80 INT322756 Negative_regulation of Tsc1 1 0.07 1.4 0.26
81 INT151719 Negative_regulation of Positive_regulation of Ctnnb1 1 0.23 1.9 0.24
82 INT104167 Negative_regulation of Phosphorylation of Nfasc 1 0.24 0.76 0.23
83 INT202501 Regulation of Negative_regulation of Nfasc 2 0.21 1.42 0.22
84 INT237618 Localization of Ank3 2 0.55 0.4 0.22
85 INT217832 Negative_regulation of Gene_expression of TSC1 5 0.04 5.45 0.21
86 INT240411 Negative_regulation of Binding of Myo5a 1 0.09 0.97 0.21
87 INT202492 Phosphorylation of Nfasc 1 0.19 1.02 0.19
88 INT99392 Negative_regulation of Localization of Ctnnb1 2 0.59 1.43 0.17
89 INT151721 Negative_regulation of Localization of Ctnnb1 1 0.23 0.96 0.17
90 INT289128 Negative_regulation of Gene_expression of DVL1 1 0.07 0.31 0.17
91 INT289117 Negative_regulation of DVL1 1 0.07 0.31 0.17
92 INT325506 Positive_regulation of Localization of Ctnnb1 1 0.05 0.28 0.17
93 INT317342 Positive_regulation of Localization of Nfasc 1 0.62 0 0.17
94 INT55089 Positive_regulation of Positive_regulation of Wnt7a 2 0.27 0.06 0.16
95 INT130374 Transcription of Ctnnb1 1 0.19 0 0.13
96 INT104171 Negative_regulation of Protein_catabolism of Nfasc 1 0.24 0.42 0.13
97 INT287922 Phosphorylation of DVL1 4 0.20 1.21 0.12
98 INT243912 Gene_expression of Nlgn2 2 0.37 0.22 0.12
99 INT192783 Phosphorylation of Myo5a 1 0.04 2.01 0.12
100 INT104169 Positive_regulation of Protein_catabolism of Nfasc 1 0.19 0.35 0.11
101 INT254015 Positive_regulation of Ank3 1 0.34 0 0.1
102 INT240716 Negative_regulation of Gene_expression of Atp2b2 1 0.09 0.78 0.1
103 INT127168 Positive_regulation of Positive_regulation of NFASC 1 0.02 0.71 0.1
104 INT251222 Localization of Nlgn2 1 0.20 0 0.1
105 INT160258 Negative_regulation of Myo5a 3 0.35 3.96 0.09
106 INT202472 Protein_catabolism of Nfasc 1 0.18 0.85 0.09
107 INT173222 Negative_regulation of Negative_regulation of TSC1 1 0.01 0.92 0.09
108 INT240713 Gene_expression of Atp2b2 1 0.14 1.16 0.09
109 INT254469 Positive_regulation of Binding of Nfasc 1 0.04 0.1 0.08
110 INT240714 Negative_regulation of Localization of Atp2b2 1 0.09 1.3 0.08
111 INT190703 Regulation of Negative_regulation of TSC1 3 0.06 3.08 0.07
112 INT271938 Binding of Tsc1 1 0.43 3.18 0.07
113 INT287947 Binding of DVL1 3 0.10 0.95 0.06
114 INT159426 Positive_regulation of Gene_expression of Wnt7a 1 0.10 0.51 0.05
115 INT271914 Negative_regulation of Tsc1 5 0.38 3.08 0.04
116 INT192784 Positive_regulation of Gene_expression of Myo5a 2 0.45 3.39 0.04
117 INT254014 Regulation of Gene_expression of Ank3 1 0.31 0 0.04
118 INT271930 Gene_expression of Tsc1 1 0.69 6.88 0.04
119 INT246758 Gene_expression of Tsc1 1 0.11 0.55 0.04
120 INT240715 Localization of Atp2b2 1 0.16 1.07 0.04
121 INT287920 Positive_regulation of DVL1 3 0.49 1.29 0.03
122 INT190057 Positive_regulation of Negative_regulation of TSC1 2 0.01 1.08 0.03
123 INT271960 Positive_regulation of Binding of TSC1 1 0.25 0.88 0.03
124 INT272566 Gene_expression of Nlgn3 1 0.28 0 0.03
125 INT190054 Negative_regulation of Positive_regulation of TSC1 1 0.01 0.83 0.03
126 INT347866 Regulation of Gene_expression of Nfasc 1 0.15 0.07 0.03
127 INT271936 Phosphorylation of Tsc1 4 0.73 1.76 0
128 INT76959 Binding of Ctnnb1 2 0.34 0.69 0
129 INT175424 Regulation of Transcription of TSC1 2 0.05 1.39 0
130 INT287937 Positive_regulation of Positive_regulation of DVL1 2 0.12 0.52 0
131 INT271963 Phosphorylation of TSC1 2 0.31 2.02 0
132 INT300638 Transcription of DVL1 1 0.33 1.11 0
133 INT230651 Phosphorylation of Ctnnb1 1 0.10 0 0
134 INT230674 Positive_regulation of Phosphorylation of Ctnnb1 1 0.06 0 0
135 INT326137 Protein_catabolism of Ctnnb1 1 0.02 1.08 0
136 INT271965 Negative_regulation of Binding of TSC1 1 0.33 0.44 0
137 INT266460 Positive_regulation of Binding of Wnt7a 1 0.04 0.06 0
138 INT246748 Regulation of Tsc1 1 0.04 0.05 0
139 INT355576 Negative_regulation of Negative_regulation of Ctnnb1 1 0.02 1.14 0
140 INT286005 Positive_regulation of Binding of Myo5a 1 0.41 0.97 0
141 INT254013 Positive_regulation of Localization of Ank3 1 0.47 0.08 0
142 INT220769 Positive_regulation of Positive_regulation of Ctnnb1 1 0.10 0 0
143 INT246773 Phosphorylation of Tsc1 1 0.13 0.05 0
144 INT266459 Binding of Wnt7a 1 0.03 0.06 0
145 INT271913 Protein_catabolism of Tsc1 1 0.51 0.45 0
146 INT286004 Positive_regulation of Positive_regulation of Myo5a 1 0.41 0.58 0
147 INT271906 Negative_regulation of Binding of Tsc1 1 0.38 0.06 0
148 INT271927 Positive_regulation of Tsc1 1 0.44 0.4 0
149 INT271931 Negative_regulation of Gene_expression of Tsc1 1 0.38 0.44 0
150 INT322758 Positive_regulation of Localization of TSC1 1 0.06 1.4 0
151 INT331195 Positive_regulation of Negative_regulation of Tsc1 1 0.18 0.15 0
152 INT216378 Positive_regulation of Gene_expression of NFASC 1 0.12 0.06 0
153 INT343743 Negative_regulation of Regulation of Wnt7a 1 0.04 0.1 0
154 INT246757 Binding of Tsc1 1 0.06 0.19 0
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