GO:0050821

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Name protein stabilization
Categary Process
Go Slim No
Go Link GO:0050821
Unique Molecular Interactions 720
Total Molecular Interactions 1078
Total Single Events 7338
Pain Genes Associated 64

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for protein stabilization. They are ordered first by their pain relevance and then by number of times they were reported for protein stabilization. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT259233 Binding of Oprm1 and Flna 1 0.03 0.25 25.89
2 INT221180 Binding of OPRM1 and Flna 1 0.09 0.22 12.65
3 INT251170 Clu Positive_regulation of Trpv1 1 0.28 2.61 6.49
4 INT338167 Binding of CDKN2A and MC1R 1 0.42 6.14 5.76
5 INT259209 Binding of Glul and Flna 1 0.03 0 4.2
6 INT103724 Oprd1 Positive_regulation of Gtpbp4 3 0.30 0.91 4.18
7 INT259230 Negative_regulation of Binding of Oprm1 and Flna 1 0.02 0 4.15
8 INT113080 Drd1a Positive_regulation of Phosphorylation of Creb1 2 0.27 0.43 3.88
9 INT161164 Prkcg Regulation of Phosphorylation of Creb1 3 0.41 0.62 3.11
10 INT309150 Edc4 Positive_regulation of Creb1 1 0.03 3.46 3.09
11 INT103669 Hps4 Positive_regulation of Mors1 1 0.01 0 2.7
12 INT156622 Umod Regulation of Phosphorylation of Creb1 1 0.05 0.33 2.27
13 INT251164 Binding of Clu and Trpv1 1 0.19 0.44 2.23
14 INT221181 Binding of GOPC and Flna 1 0.03 0.06 2.08
15 INT158964 FosB Negative_regulation of Creb1 1 0.21 0 2.07
16 INT114927 Positive_regulation of Binding of Oprm1 and Creb1 1 0.17 0.28 2.07
17 INT114923 Binding of Oprm1 and Creb1 1 0.16 0.28 2.06
18 INT124133 Camk2a Regulation of Phosphorylation of Creb1 1 0.46 0 2
19 INT65025 Binding of Oprm1 and Hps4 1 0.01 0 1.93
20 INT186435 Prkcg Regulation of Creb1 1 0.44 0.45 1.9
21 INT186432 Prkaca Regulation of Creb1 1 0.14 0.45 1.9
22 INT43447 Binding of H3 and Hps4 1 0.07 0 1.82
23 INT186433 Trib3 Regulation of Phosphorylation of Creb1 1 0.03 0.32 1.71
24 INT103725 Negative_regulation of Oprd1 Positive_regulation of Gtpbp4 1 0.17 0.38 1.65
25 INT103726 Regulation of Oprd1 Positive_regulation of Gtpbp4 1 0.10 0.38 1.64
26 INT131574 Negative_regulation of Ephb1 Negative_regulation of Gene_expression of Creb1 1 0.41 0.33 1.58
27 INT221182 Negative_regulation of Binding of OPRM1 and Flna 1 0.07 0 1.57
28 INT114926 Creb1 Negative_regulation of Positive_regulation of Oprm1 1 0.13 0.23 1.56
29 INT121747 Prkcg Negative_regulation of Positive_regulation of Creb1 1 0.16 0.2 1.5
30 INT121741 Prkaca Negative_regulation of Positive_regulation of Creb1 1 0.10 0.2 1.49
31 INT73650 Binding of Pim3 and Creb1 1 0.03 2.48 1.47
32 INT21425 Binding of Pomc and Gtpbp4 1 0.01 0.1 1.45
33 INT259232 Binding of Flna and Positive_regulation of Localization of Oprm1 1 0.03 0 1.39
34 INT168724 Creb1 Negative_regulation of Gene_expression of Calca 1 0.46 1.09 1.38
35 INT168721 Positive_regulation of Creb1 Positive_regulation of Calca 1 0.53 1.07 1.37
36 INT106850 P2ry2 Positive_regulation of Phosphorylation of Creb1 2 0.49 0.73 1.36
37 INT168722 Creb1 Positive_regulation of Calca 1 0.73 1.05 1.35
38 INT259211 Binding of Ppp1r9b and Flna 1 0.06 0 1.33
39 INT131886 Creb1 Positive_regulation of Gene_expression of Prkcg 1 0.03 0 1.31
40 INT162163 CDKN2A Positive_regulation of PLD2 1 0.24 0 1.24
41 INT136250 Phosphorylation of Tff3 Regulation of Creb1 1 0.02 0.18 1.24
42 INT259229 Positive_regulation of Binding of Oprm1 and Flna 1 0.02 0 1.23
43 INT136256 Creb1 Regulation of SGCG 1 0.26 0.18 1.23
44 INT136258 Creb1 Regulation of GRIA1 1 0.26 0.18 1.23
45 INT131195 Creb1 Positive_regulation of Positive_regulation of Drd1a 2 0.27 0.61 1.22
46 INT21424 Binding of Penk and Gtpbp4 1 0.02 0.16 1.2
47 INT124435 Gene_expression of Chrna9 Positive_regulation of Phosphorylation of Creb1 1 0.11 0.6 1.17
48 INT64259 Binding of Gtpbp4 and Ptprg 1 0.06 0 1.1
49 INT107567 Hps4 Positive_regulation of Localization of Il1b 1 0.01 0.09 1.08
50 INT172757 Rnpep Positive_regulation of Hps4 1 0.00 0 1.08
51 INT107564 Hps4 Regulation of Localization of Il1b 1 0.01 0.1 1.07
52 INT156462 Creb1 Regulation of Ephb1 1 0.29 0 1.07
53 INT107566 Penk Regulation of Hps4 1 0.00 0.1 1.04
54 INT107565 Hps4 Regulation of Mtr 1 0.00 0.1 1.04
55 INT74027 Creb1 Regulation of Jun 4 0.27 1.04 1.02
56 INT61637 Binding of P2ry2 and Gtpbp4 1 0.02 0.1 0.99
57 INT38579 Binding of POMC and Hps4 1 0.00 0.32 0.99
58 INT302309 Hps4 Positive_regulation of Cia1 1 0.01 1.34 0.95
59 INT153685 Binding of Bcl2l11 and Gtpbp4 1 0.08 0.76 0.93
60 INT186431 Trib3 Regulation of Creb1 1 0.03 0.23 0.92
61 INT252879 Creb1 Positive_regulation of Gene_expression of Tacr1 1 0.03 0.24 0.91
62 INT219037 Creb1 Positive_regulation of Transcription of Bdnf 2 0.43 1.07 0.9
63 INT113946 Binding of FLNA and OPRM1 1 0.10 0.37 0.9
64 INT77253 Binding of gr and Creb1 1 0.03 0.4 0.9
65 INT309140 Dlat Positive_regulation of Creb1 1 0.06 1.1 0.9
66 INT251159 Binding of Clu and Positive_regulation of Trpv1 1 0.16 0 0.87
67 INT73653 Binding of Creb1 and Fos 1 0.40 1.49 0.87
68 INT129881 Binding of Calr and Cbll1 1 0.00 0.58 0.84
69 INT320120 MTX1 Positive_regulation of PTEN 1 0.04 0.09 0.82
70 INT228255 Binding of Akt1 and Pten 2 0.43 1.78 0.8
71 INT109142 Calca Positive_regulation of Transcription of Creb1 1 0.47 0.13 0.8
72 INT114924 Creb1 Regulation of Positive_regulation of Oprm1 1 0.09 0.13 0.79
73 INT186439 Prkaca Regulation of Phosphorylation of Creb1 1 0.06 0.08 0.79
74 INT131194 Creb1 Positive_regulation of Gene_expression of Pdyn 1 0.26 0.08 0.79
75 INT56459 ADRA2C Positive_regulation of Localization of AHSP 1 0.23 0 0.78
76 INT142454 Npff Positive_regulation of Gtpbp4 1 0.56 0 0.78
77 INT142455 Binding of Npff and Gtpbp4 1 0.40 0 0.78
78 INT224280 Bdnf Positive_regulation of Creb1 3 0.30 0.62 0.77
79 INT106335 Olr1254 Positive_regulation of Phosphorylation of Creb1 1 0.03 0 0.76
80 INT109141 Calca Positive_regulation of Creb1 1 0.47 0.13 0.76
81 INT109143 Calca Positive_regulation of Phosphorylation of Creb1 1 0.47 0.13 0.76
82 INT316673 Binding of CALR and LRP1 1 0.39 1.89 0.74
83 INT186436 Phosphorylation of Creb1 Regulation of Transcription of Jun 1 0.21 0.44 0.73
84 INT186445 Creb1 Regulation of Transcription of FOS 1 0.49 0.44 0.73
85 INT33575 ADRB1 Positive_regulation of Localization of Ahsp 1 0.00 0.33 0.73
86 INT186443 Phosphorylation of Creb1 Regulation of Transcription of FOS 1 0.49 0.44 0.73
87 INT186438 Creb1 Regulation of Transcription of Jun 1 0.21 0.44 0.73
88 INT186444 Creb1 Regulation of FOS 1 0.49 0.43 0.72
89 INT317585 Binding of Lbp and Ppap2b 1 0.03 0.78 0.72
90 INT317586 Binding of SCLY and Ppap2b 1 0.00 0.78 0.72
91 INT186442 Phosphorylation of Creb1 Regulation of FOS 1 0.49 0.43 0.72
92 INT276213 Pten Regulation of Phosphorylation of Akt1 1 0.51 0.61 0.72
93 INT186440 Phosphorylation of Creb1 Regulation of Jun 1 0.21 0.43 0.72
94 INT262574 Gnaq Positive_regulation of Prkca 1 0.00 0.57 0.71
95 INT251169 Clu Regulation of Ca2 1 0.03 0.66 0.7
96 INT251166 Clu Positive_regulation of Trpc3 1 0.09 0.75 0.67
97 INT113931 Mors1 Positive_regulation of Gtpbp4 1 0.02 0 0.67
98 INT251171 Clu Positive_regulation of C6 1 0.05 0.75 0.67
99 INT111555 Negative_regulation of Npr1 Negative_regulation of Positive_regulation of Creb1 1 0.02 0.58 0.66
100 INT266064 Binding of PAG1 and Creb1 1 0.04 1.52 0.65
101 INT266049 Binding of Ceacam3 and Creb1 1 0.14 1.53 0.65
102 INT318981 Binding of CALR and GOPC 1 0.03 0.77 0.64
103 INT251188 Clu Positive_regulation of TRPV1 1 0.01 0.23 0.64
104 INT266047 Creb1 Regulation of Ceacam3 1 0.20 1.15 0.62
105 INT186429 Camk2a Regulation of Regulation of Creb1 1 0.09 0.09 0.62
106 INT79210 Hps4 Negative_regulation of Mme 1 0.00 0 0.62
107 INT113962 OPRM1 Regulation of CREB1 1 0.39 0.31 0.6
108 INT297340 Apoe Regulation of Binding of Smo 1 0.10 1.1 0.6
109 INT251167 Clu Positive_regulation of Trpc6 1 0.12 0.2 0.6
110 INT98725 Msr1 Positive_regulation of Gene_expression of Creb1 1 0.00 0.09 0.6
111 INT161387 Binding of PNOC and GTPBP4 1 0.03 1.05 0.59
112 INT251168 Clu Positive_regulation of Trpc7 1 0.15 0.2 0.59
113 INT186434 Trib3 Positive_regulation of Phosphorylation of Creb1 1 0.05 0.26 0.58
114 INT317639 Igf1 Regulation of Creb1 1 0.23 0.16 0.57
115 INT317637 Ngf Regulation of Creb1 1 0.10 0.11 0.57
116 INT27871 Binding of FCGR1B and HSPD1 1 0.01 1.93 0.56
117 INT73656 Creb1 Positive_regulation of Transcription of Pdyn 1 0.42 0.97 0.56
118 INT27872 Positive_regulation of Binding of FCGR1B and HSPD1 1 0.01 1.93 0.56
119 INT296169 Binding of Htr4 and Creb1 1 0.49 0.1 0.56
120 INT105424 Creb1 Positive_regulation of Gene_expression of Penk 1 0.49 0 0.55
121 INT333991 Binding of FLNA and SELL 1 0.00 1.69 0.55
122 INT343913 Binding of FOS and Smad3 1 0.19 0.92 0.54
123 INT222691 Negative_regulation of Binding of FLNA and TNF 1 0.14 1.92 0.54
124 INT114928 Positive_regulation of Creb1 Positive_regulation of Positive_regulation of Oprm1 1 0.16 0.05 0.54
125 INT222692 Binding of FLNA and TNF 1 0.12 1.92 0.53
126 INT120383 PRKCD Positive_regulation of Localization of EPHB2 1 0.29 0.42 0.52
127 INT120384 PRKCD Positive_regulation of Localization of HSPG2 1 0.29 0.42 0.51
128 INT120382 PRKCD Positive_regulation of Localization of DYT10 1 0.29 0.42 0.51
129 INT81004 Htr1a Positive_regulation of Gtpbp4 1 0.20 0 0.5
130 INT324816 Hspd1 Positive_regulation of Gene_expression of Ik 1 0.00 1.59 0.5
131 INT320121 Binding of PTEN and TNF 1 0.05 0.76 0.49
132 INT47226 Asap1 Regulation of Hps4 1 0.10 0.18 0.49
133 INT219038 Creb1 Regulation of Gene_expression of Bdnf 1 0.25 0.25 0.49
134 INT156155 Binding of HCFC1 and TFAM 1 0.04 0.74 0.49
135 INT319718 Binding of Crebbp and Creb1 1 0.10 1.68 0.48
136 INT142826 UPF1 Positive_regulation of CREB1 1 0.11 0 0.46
137 INT145260 Binding of CLU and App 1 0.00 0.74 0.46
138 INT276218 Binding of Akt1 and Pten 1 0.26 0.08 0.46
139 INT317640 Slc3a1 Positive_regulation of Creb1 1 0.12 0.58 0.46
140 INT161162 Creb1 Regulation of Nts 1 0.19 0.15 0.45
141 INT307781 Apoa1 Positive_regulation of LCAT 1 0.76 1.19 0.45
142 INT259208 Ca2 Positive_regulation of Phosphorylation of Creb1 1 0.04 0 0.45
143 INT317636 Creb1 Positive_regulation of Phosphorylation of Hmmr 1 0.04 0.55 0.45
144 INT283731 Trib3 Positive_regulation of Creb1 2 0.01 0.16 0.44
145 INT213027 Binding of Apoa1 and Scarb1 6 0.09 7.52 0.43
146 INT309113 Edc4 Positive_regulation of Gene_expression of Creb1 1 0.03 0.45 0.43
147 INT106333 Olr1254 Positive_regulation of Creb1 1 0.02 0 0.43
148 INT321046 Anpep Regulation of Negative_regulation of Hps4 1 0.02 0.25 0.43
149 INT309145 Positive_regulation of Edc4 Positive_regulation of Creb1 1 0.02 0.35 0.42
150 INT160046 INPPL1 Regulation of Gene_expression of PTEN 1 0.41 0.6 0.42
151 INT307780 Apoa1 Positive_regulation of Soat1 1 0.04 1.14 0.42
152 INT160047 PTEN Regulation of Gene_expression of AKT1 1 0.33 0.6 0.42
153 INT160049 PTEN Regulation of Gene_expression of INPPL1 1 0.41 0.6 0.42
154 INT158032 Binding of CDKN2A and KRT20 1 0.28 0.59 0.4
155 INT56876 Regulation of Binding of Cd36 and Gtpbp4 1 0.00 0 0.4
156 INT56875 Binding of Cd36 and Gtpbp4 1 0.00 0 0.4
157 INT51341 Binding of Pomc and Clu 1 0.14 0 0.38
158 INT291616 Cby1 Positive_regulation of Gene_expression of Smad7 1 0.00 0.79 0.38
159 INT316675 Binding of CALR and SFTPD 1 0.35 0.96 0.37
160 INT173356 Gnaq Positive_regulation of CDK20 1 0.06 0 0.37
161 INT340607 Bdnf Regulation of Gene_expression of Creb1 1 0.36 0.31 0.36
162 INT198970 GAPDH Negative_regulation of ADAMTS3 1 0.47 0 0.35
163 INT257741 HRAS Negative_regulation of PTEN 1 0.15 1.06 0.35
164 INT168202 Msx1 Negative_regulation of Gene_expression of Mc1r 1 0.21 0.49 0.35
165 INT198971 GAPDH Negative_regulation of ADAMTS5 1 0.47 0 0.35
166 INT198969 GAPDH Negative_regulation of TIMP1 1 0.47 0 0.35
167 INT257737 Positive_regulation of HRAS Negative_regulation of PTEN 1 0.17 1.07 0.35
168 INT204071 HP Positive_regulation of Gene_expression of CDKN2A 1 0.00 3.48 0.34
169 INT297342 Binding of Gnb5 and Smo 1 0.02 1.67 0.34
170 INT130803 MC1R Regulation of Positive_regulation of Cdkn2a 1 0.17 0.82 0.34
171 INT39594 TPO Positive_regulation of CALR 1 0.30 0.91 0.32
172 INT109282 Gdi2 Negative_regulation of Gtpbp4 1 0.01 0.13 0.32
173 INT113950 FLNA Regulation of Oprd1 1 0.00 0.16 0.32
174 INT126851 Prkcg Positive_regulation of Creb1 1 0.46 0.09 0.32
175 INT126852 Prkaca Positive_regulation of Creb1 1 0.27 0.09 0.32
176 INT259130 KLK7 Positive_regulation of Binding of DSG1 1 0.51 0.91 0.31
177 INT259131 KLK7 Positive_regulation of DSG1 1 0.51 0.91 0.31
178 INT186430 Creb1 Positive_regulation of Trib3 1 0.04 0.17 0.3
179 INT324830 Hspd1 Positive_regulation of IFNA1 1 0.04 0.46 0.3
180 INT118655 Bdnf Positive_regulation of Phosphorylation of Creb1 1 0.44 0.16 0.3
181 INT118653 Binding of Bdnf and Creb1 1 0.39 0.19 0.3
182 INT73657 Binding of Jun and Creb1 1 0.25 0.5 0.29
183 INT75056 Binding of MC1R and Msx1 1 0.00 0.17 0.29
184 INT156149 Binding of HCFC1 and POU4F1 1 0.27 0.39 0.28
185 INT156154 POU4F1 Positive_regulation of HCFC1 1 0.36 0.38 0.28
186 INT71550 GTPBP4 Regulation of Localization of INS 1 0.00 0.16 0.28
187 INT179425 Fig4 Regulation of Creb1 1 0.02 0.32 0.28
188 INT64892 ANTXR1 Regulation of Gtpbp4 1 0.00 0.47 0.28
189 INT283732 Prkaca Positive_regulation of Creb1 1 0.03 0 0.28
190 INT51858 Akr1d1 Positive_regulation of Phosphorylation of Creb1 1 0.01 0 0.27
191 INT213029 Positive_regulation of Binding of Apoa1 and Scarb1 1 0.09 3.38 0.27
192 INT191504 CPN2 Positive_regulation of NLRP3 1 0.00 0.37 0.27
193 INT147593 Binding of CDK4 and CDKN2A 1 0.42 0.23 0.26
194 INT147592 Positive_regulation of Binding of CDK4 and CDKN2A 1 0.44 0.23 0.26
195 INT235013 Binding of DSG1 and Adam17 1 0.07 1.34 0.26
196 INT194670 CREB1 Regulation of Gene_expression of CD4 1 0.05 0.07 0.25
197 INT168203 Binding of Mc1r and Msx1 1 0.19 0.64 0.25
198 INT194714 CREB1 Regulation of Gene_expression of IK 1 0.00 0.07 0.25
199 INT111909 Binding of HSPD1 and CCT4 1 0.29 0.48 0.25
200 INT111908 Binding of HSPD1 and AP4B1 1 0.03 0.48 0.25

Single Events

The table below shows the top 100 pain related interactions that have been reported for protein stabilization. They are ordered first by their pain relevance and then by number of times they were reported in protein stabilization. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT11009 Phosphorylation of Creb1 458 0.82 111.34 221.97
2 INT11012 Positive_regulation of Creb1 258 0.70 84.4 132
3 INT11011 Positive_regulation of Phosphorylation of Creb1 190 0.70 49.25 112.01
4 INT49651 Gene_expression of Creb1 276 0.78 114.77 111.96
5 INT221172 Binding of Flna 32 0.42 1.37 51.59
6 INT88617 Positive_regulation of Gene_expression of Creb1 90 0.69 51.69 44.29
7 INT9298 Positive_regulation of Gtpbp4 64 0.69 12.29 41.97
8 INT11013 Negative_regulation of Phosphorylation of Creb1 55 0.59 18.74 34.66
9 INT16714 Regulation of Creb1 64 0.62 22.23 33.56
10 INT11010 Regulation of Phosphorylation of Creb1 52 0.62 7.26 29.04
11 INT11014 Phosphorylation of CREB1 72 0.81 26.35 25.64
12 INT61160 Negative_regulation of Gene_expression of Creb1 37 0.59 17.95 23.17
13 INT106175 Positive_regulation of Positive_regulation of Creb1 37 0.70 13.89 22.46
14 INT61159 Regulation of Gene_expression of Creb1 46 0.62 24.07 20.52
15 INT61158 Negative_regulation of Creb1 33 0.59 11.54 18.06
16 INT30440 Gene_expression of Hps4 15 0.29 2.39 15.31
17 INT18430 Positive_regulation of Hps4 14 0.24 0.81 14.82
18 INT94774 Regulation of CDKN2A 43 0.60 44.41 13.99
19 INT78472 Gene_expression of CDKN2A 223 0.78 173.76 13.61
20 INT21421 Regulation of Gtpbp4 15 0.30 2.7 13.49
21 INT16713 Binding of Creb1 53 0.48 20.24 13.06
22 INT221167 Gene_expression of Flna 11 0.60 0.69 11.81
23 INT30236 Negative_regulation of Hps4 8 0.15 1.03 11.4
24 INT151168 Gene_expression of Pten 60 0.78 35.63 10.54
25 INT111335 Gene_expression of HSPD1 57 0.75 55.51 10.38
26 INT67915 Negative_regulation of Gtpbp4 18 0.33 6.31 10.17
27 INT58986 Gene_expression of Clu 17 0.77 8.35 9.61
28 INT68373 Negative_regulation of FLNA 59 0.57 60.46 9.55
29 INT6125 Localization of Ahsp 35 0.78 9.17 9.42
30 INT54588 Positive_regulation of CREB1 38 0.67 12.01 9.18
31 INT18429 Localization of Hps4 8 0.31 1.23 9.01
32 INT119831 Gene_expression of PTEN 55 0.75 40.37 8.57
33 INT93673 Transcription of Creb1 19 0.66 9.27 8.26
34 INT221173 Negative_regulation of Binding of Flna 4 0.33 0.13 8.25
35 INT53487 Gene_expression of TSC1 81 0.58 77.71 7.94
36 INT87271 Positive_regulation of Phosphorylation of CREB1 27 0.66 12.87 7.91
37 INT68434 Gene_expression of Gtpbp4 15 0.54 5.5 7.91
38 INT92138 Binding of CDKN2A 28 0.37 25.64 7.47
39 INT43441 Binding of Hps4 7 0.24 0.46 7.43
40 INT6341 Binding of Gtpbp4 11 0.44 1.54 7.3
41 INT77756 Positive_regulation of GTPBP4 16 0.11 2.6 7.29
42 INT86867 Regulation of CREB1 15 0.46 4.95 7.28
43 INT8579 Gene_expression of Apoa1 13 0.76 35.89 7.21
44 INT106330 Regulation of Positive_regulation of Creb1 11 0.56 5.57 7.06
45 INT31911 Regulation of Hps4 5 0.19 2.16 6.83
46 INT114642 Negative_regulation of Positive_regulation of Creb1 12 0.57 2.32 6.75
47 INT103723 Regulation of Positive_regulation of Gtpbp4 5 0.22 1.56 6.35
48 INT6667 Gene_expression of CREB1 27 0.77 6.29 5.84
49 INT61986 Localization of Creb1 16 0.69 2.12 5.66
50 INT125467 Positive_regulation of Gene_expression of CDKN2A 35 0.63 39.07 5.56
51 INT72000 Gene_expression of Gnaq 17 0.75 3.12 5.48
52 INT13295 Positive_regulation of Cdkn2a 18 0.68 13.02 5.47
53 INT51337 Binding of Clu 3 0.12 0.05 5.45
54 INT89794 Positive_regulation of CDKN2A 58 0.67 50.18 5.38
55 INT74614 Positive_regulation of Apoa1 16 0.68 23.95 5.04
56 INT113948 Gene_expression of FLNA 32 0.73 36.06 4.81
57 INT181886 Gene_expression of Apoa1 40 0.64 40.53 4.56
58 INT17020 Localization of AHSP 11 0.80 3.82 4.34
59 INT39948 Binding of FLNA 45 0.42 58.05 4.27
60 INT74203 Positive_regulation of Positive_regulation of Gtpbp4 6 0.50 0.33 4.13
61 INT6126 Gene_expression of Ahsp 16 0.67 7.72 4.08
62 INT221168 Localization of Flna 1 0.58 0.05 4.05
63 INT63880 Positive_regulation of FLNA 29 0.59 13.88 3.97
64 INT276198 Positive_regulation of Pten 1 0.52 5.02 3.88
65 INT73981 Gene_expression of Hspd1 18 0.75 5.69 3.72
66 INT120072 Gene_expression of Smad7 38 0.74 20.87 3.69
67 INT151171 Positive_regulation of Pten 20 0.55 13.3 3.54
68 INT73463 Positive_regulation of Gene_expression of TSC1 20 0.38 14.59 3.53
69 INT208291 Negative_regulation of Pten 2 0.44 5.42 3.36
70 INT78471 Regulation of Gene_expression of CDKN2A 13 0.45 12.52 3.28
71 INT11015 Regulation of Phosphorylation of CREB1 4 0.46 1.45 3.17
72 INT72618 Regulation of Tcf3 5 0.44 1.48 3.16
73 INT12410 Negative_regulation of Ahsp 10 0.29 3.49 3.07
74 INT192676 Binding of PTEN 14 0.46 10.58 3.06
75 INT10830 Regulation of Apoa1 11 0.44 15.1 3.04
76 INT50559 Binding of A1cf 4 0.34 0.8 2.97
77 INT221171 Positive_regulation of Localization of Flna 1 0.39 0.05 2.9
78 INT111554 Positive_regulation of Regulation of Creb1 4 0.50 2.12 2.85
79 INT156021 Positive_regulation of Transcription of Creb1 8 0.57 3.36 2.83
80 INT184477 Negative_regulation of Pten 27 0.59 15.61 2.8
81 INT78248 Negative_regulation of Cdkn2a 17 0.59 15.15 2.8
82 INT30437 Negative_regulation of Gene_expression of Hps4 1 0.03 0 2.74
83 INT35946 Positive_regulation of Clu 12 0.69 4.92 2.73
84 INT119383 Gene_expression of Pten 11 0.59 10.33 2.73
85 INT21712 Positive_regulation of APOA1 32 0.67 21.64 2.64
86 INT98919 Negative_regulation of Phosphorylation of CREB1 8 0.58 2.4 2.63
87 INT99550 Regulation of FLNA 51 0.54 27.88 2.58
88 INT46646 Localization of FLNA 19 0.73 18.83 2.53
89 INT259224 Negative_regulation of Flna 1 0.23 0.15 2.51
90 INT119838 Positive_regulation of PTEN 25 0.67 21.71 2.5
91 INT92141 Negative_regulation of CDKN2A 53 0.57 44.23 2.48
92 INT338170 Regulation of Regulation of CDKN2A 1 0.44 0.96 2.46
93 INT181880 Positive_regulation of Apoa1 19 0.66 21.19 2.43
94 INT32920 Gene_expression of Msx1 19 0.71 4.24 2.42
95 INT54555 Negative_regulation of CALR 10 0.41 4.41 2.4
96 INT27880 Positive_regulation of HSPD1 17 0.65 18.16 2.23
97 INT221177 Negative_regulation of Gene_expression of Flna 2 0.33 0 2.22
98 INT60279 Gene_expression of VHL 70 0.78 75.21 2.21
99 INT87168 Positive_regulation of Binding of Creb1 4 0.48 4.6 2.21
100 INT179885 Regulation of PTEN 8 0.26 11.88 2.18
101 INT152436 Positive_regulation of Gene_expression of HSPD1 12 0.67 10.06 2.16
102 INT224615 Negative_regulation of Gene_expression of Pten 7 0.59 2.99 2.09
103 INT317583 Positive_regulation of Ppap2b 1 0.09 2.14 2.09
104 INT276201 Phosphorylation of Pten 1 0.61 1.31 2.08
105 INT94772 Gene_expression of Cdkn2a 14 0.75 8.25 2.04
106 INT72616 Negative_regulation of Tcf3 2 0.41 0.97 2.04
107 INT221179 Regulation of Flna 1 0.24 0.13 2.04
108 INT49313 Positive_regulation of Gene_expression of Apoa1 3 0.68 9.55 2.01
109 INT70526 Binding of CALR 11 0.35 7.09 1.97
110 INT21941 Regulation of CALR 7 0.53 3.88 1.96
111 INT112880 Positive_regulation of Gnaq 17 0.49 1.97 1.95
112 INT68435 Regulation of Gene_expression of Gtpbp4 4 0.34 0.96 1.89
113 INT9297 Localization of Gtpbp4 4 0.17 0.88 1.89
114 INT56925 Negative_regulation of TSC1 54 0.52 63.39 1.87
115 INT57618 Binding of GTPBP4 9 0.43 1.61 1.87
116 INT99964 Gene_expression of A1cf 7 0.66 12.71 1.87
117 INT22863 Negative_regulation of Apoa1 10 0.57 10.68 1.86
118 INT49347 Negative_regulation of Clu 4 0.58 1.63 1.79
119 INT27881 Binding of HSPD1 10 0.31 9.2 1.78
120 INT174924 Gene_expression of Smad7 6 0.41 3.59 1.76
121 INT174923 Positive_regulation of Gene_expression of Smad7 3 0.37 2.3 1.73
122 INT221166 Positive_regulation of Flna 2 0.39 0.09 1.7
123 INT19265 Negative_regulation of Localization of AHSP 3 0.59 0.62 1.69
124 INT72676 Gene_expression of APOA1 34 0.75 34.15 1.67
125 INT96823 Positive_regulation of Positive_regulation of GTPBP4 3 0.05 0.41 1.67
126 INT97062 Binding of PML 10 0.41 11.63 1.65
127 INT276171 Positive_regulation of Gene_expression of Pten 3 0.52 7.24 1.64
128 INT156484 Binding of Apoa1 4 0.47 6.78 1.63
129 INT110189 Regulation of Gnaq 3 0.02 0.26 1.63
130 INT98687 Gene_expression of Calr 38 0.61 7.03 1.59
131 INT69917 Negative_regulation of CREB1 8 0.58 2.28 1.59
132 INT71999 Negative_regulation of Gene_expression of Gnaq 3 0.41 0.08 1.56
133 INT151169 Positive_regulation of Gene_expression of Pten 15 0.45 12.88 1.53
134 INT32040 Positive_regulation of CPN2 6 0.35 0.67 1.53
135 INT172752 Protein_catabolism of Hps4 2 0.16 0.22 1.51
136 INT259219 Negative_regulation of Negative_regulation of Flna 1 0.23 0 1.47
137 INT30439 Positive_regulation of Gene_expression of Hps4 1 0.02 0 1.47
138 INT181881 Positive_regulation of Gene_expression of Apoa1 13 0.48 14.31 1.45
139 INT228249 Binding of Pten 7 0.48 3.26 1.45
140 INT281470 Regulation of Gene_expression of Pten 4 0.39 1.13 1.42
141 INT276196 Positive_regulation of Phosphorylation of Pten 1 0.38 0.19 1.41
142 INT304045 Transcription of PTEN 2 0.51 4.12 1.4
143 INT53775 Gene_expression of Hspd1 21 0.78 31.25 1.38
144 INT78470 Negative_regulation of Gene_expression of CDKN2A 14 0.59 14.44 1.38
145 INT181882 Localization of Apoa1 8 0.71 7.94 1.37
146 INT276181 Negative_regulation of Gene_expression of Pten 1 0.44 2.48 1.37
147 INT214073 Binding of TSC1 9 0.37 22 1.34
148 INT140647 Gene_expression of DSG1 45 0.75 27.95 1.33
149 INT79099 Negative_regulation of Positive_regulation of Gtpbp4 4 0.20 0.06 1.31
150 INT35944 Regulation of Clu 4 0.20 0.15 1.3
151 INT61756 Positive_regulation of A1cf 8 0.57 4.94 1.29
152 INT21950 Positive_regulation of Localization of Ahsp 5 0.44 0.81 1.28
153 INT164706 Positive_regulation of Park7 2 0.50 2.28 1.28
154 INT66118 Binding of Calr 4 0.46 1.46 1.26
155 INT98923 Negative_regulation of Localization of Creb1 3 0.50 0.66 1.26
156 INT167056 Gene_expression of CALR 29 0.75 20.05 1.25
157 INT120076 Positive_regulation of Gene_expression of Smad7 16 0.65 11.33 1.25
158 INT53776 Positive_regulation of Hspd1 17 0.70 10.64 1.23
159 INT73176 Positive_regulation of Hspd1 5 0.35 3.96 1.22
160 INT110188 Regulation of Gene_expression of Gnaq 2 0.25 0.85 1.22
161 INT251180 Phosphorylation of Clu 1 0.29 0.79 1.22
162 INT122988 Gene_expression of CLU 28 0.75 24.07 1.21
163 INT74443 Positive_regulation of PML 11 0.53 12.52 1.21
164 INT190014 Regulation of Pten 8 0.62 6.03 1.2
165 INT138726 Positive_regulation of Gene_expression of Msx1 5 0.53 1.73 1.2
166 INT57619 Gene_expression of GTPBP4 3 0.04 0.22 1.2
167 INT183068 Gene_expression of SMO 2 0.17 0.27 1.2
168 INT72614 Negative_regulation of Regulation of Tcf3 1 0.41 0.17 1.2
169 INT119832 Positive_regulation of Gene_expression of PTEN 12 0.49 7.12 1.19
170 INT112891 Regulation of Gene_expression of HSPD1 2 0.43 3.98 1.17
171 INT234422 Gene_expression of PML 14 0.75 15.93 1.14
172 INT16157 Gene_expression of CPN2 4 0.26 0 1.14
173 INT181879 Negative_regulation of Apoa1 8 0.55 8.18 1.11
174 INT184720 Negative_regulation of Smad3 8 0.55 5.23 1.1
175 INT142831 Positive_regulation of Gene_expression of CREB1 3 0.69 0.08 1.1
176 INT81440 Regulation of GTPBP4 3 0.02 0.09 1.1
177 INT233561 Gene_expression of Clu 14 0.66 45.63 1.07
178 INT220465 Binding of BAG6 7 0.30 6.41 1.07
179 INT42104 Regulation of Cdkn2a 4 0.44 5.67 1.06
180 INT71476 Negative_regulation of Regulation of Creb1 1 0.18 0.17 1.06
181 INT101569 Positive_regulation of Gene_expression of A1cf 4 0.49 6.35 1.05
182 INT17627 Binding of Ahsp 3 0.25 1.83 1.04
183 INT142829 Transcription of CREB1 9 0.46 3.37 1.03
184 INT72002 Negative_regulation of Gnaq 7 0.35 0.2 1.02
185 INT86798 Positive_regulation of Binding of Gtpbp4 1 0.29 0 1.01
186 INT8231 Positive_regulation of Gene_expression of Ahsp 2 0.04 1.16 1
187 INT280495 Regulation of PPAP2B 1 0.06 1.64 1
188 INT215363 Regulation of HSPD1 4 0.51 2.74 0.99
189 INT234952 Protein_catabolism of DSG1 3 0.96 5.86 0.98
190 INT21109 Phosphorylation of Gtpbp4 2 0.22 0.28 0.97
191 INT73465 Transcription of TSC1 4 0.07 3.47 0.96
192 INT21940 Positive_regulation of CALR 15 0.40 17.42 0.95
193 INT5423 Protein_catabolism of CPN2 4 0.72 0 0.94
194 INT338168 Positive_regulation of Binding of CDKN2A 1 0.49 0.52 0.94
195 INT72672 Positive_regulation of Gene_expression of APOA1 4 0.67 3.81 0.89
196 INT142423 Negative_regulation of Positive_regulation of FLNA 2 0.05 0.99 0.89
197 INT100273 Localization of Clu 4 0.61 0.49 0.88
198 INT61755 Negative_regulation of A1cf 8 0.58 6.32 0.87
199 INT120393 Negative_regulation of PRKCD 3 0.22 1.07 0.86
200 INT120396 Positive_regulation of Localization of PRKCD 1 0.26 0.42 0.85
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