GO:0050829

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Name defense response to Gram-negative bacterium
Categary Process
Go Slim No
Go Link GO:0050829
Unique Molecular Interactions 1622
Total Molecular Interactions 2416
Total Single Events 21963
Pain Genes Associated 33

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for defense response to Gram-negative bacterium. They are ordered first by their pain relevance and then by number of times they were reported for defense response to Gram-negative bacterium. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT179502 Binding of Cd14 and Tlr4 29 0.39 13.77 5.73
2 INT95068 Tlr4 Positive_regulation of IL1B 1 0.03 4.54 5.6
3 INT182124 Binding of IRF6 and TLR4 14 0.10 16.11 4.65
4 INT64718 IL1B Positive_regulation of Gene_expression of IL6 15 0.59 9.37 4.48
5 INT57985 Il1b Positive_regulation of Il6 5 0.59 1.66 3.53
6 INT64719 IL1B Positive_regulation of IL6 7 0.41 6.84 3.14
7 INT150888 Il1a Regulation of Il6 1 0.10 3.47 2.93
8 INT86180 SFTPA1 Positive_regulation of Localization of IL6 2 0.06 2.01 2.85
9 INT222522 Il1a Positive_regulation of Gene_expression of Il6 2 0.06 1.79 2.79
10 INT91649 Binding of Lbp and SPECC1 1 0.12 2.88 2.78
11 INT154187 Il6 Positive_regulation of Gene_expression of Cd2 1 0.08 3.07 2.71
12 INT154188 Il6 Positive_regulation of Gene_expression of Atf3 1 0.76 3.07 2.71
13 INT212505 Binding of pr and Lbp 1 0.01 4.26 2.62
14 INT115367 Binding of IL6 and IL6R 12 0.07 8.16 2.36
15 INT61733 Tlr4 Positive_regulation of Gene_expression of Tnf 3 0.26 1.99 2.36
16 INT124121 IL6 Positive_regulation of CCL2 1 0.26 1.84 2.25
17 INT126717 Binding of Il6 and Il6st 3 0.21 3.35 2.22
18 INT124120 IL6 Regulation of CCL2 1 0.15 1.8 2.22
19 INT94492 Il6 Positive_regulation of Gene_expression of Il1b 1 0.27 3.81 2.19
20 INT94504 Il6 Positive_regulation of Gene_expression of Tnf 1 0.30 3.8 2.19
21 INT94494 Il1b Positive_regulation of Gene_expression of Il6 1 0.27 3.81 2.19
22 INT86179 TNF Positive_regulation of Localization of IL6 5 0.35 1.66 2.17
23 INT126400 ITIH4 Positive_regulation of Gene_expression of Il6 1 0.00 2.11 2.08
24 INT81295 Ifng Positive_regulation of Gene_expression of Nos2 4 0.39 0.87 2.05
25 INT117821 Binding of Tacr1 and Cd4 1 0.34 0.86 2.02
26 INT70043 IL6 Regulation of IL10 3 0.18 3.59 2.01
27 INT164784 Il6 Positive_regulation of Gene_expression of Cx3cr1 1 0.47 2.37 1.98
28 INT278937 LEP Positive_regulation of Gene_expression of IL6 1 0.32 3.42 1.97
29 INT264953 Binding of POMC and TLR4 1 0.03 0.89 1.96
30 INT157767 Binding of TLR4 and LY96 8 0.54 4.05 1.95
31 INT156509 Il6 Regulation of Positive_regulation of Grin1 1 0.28 1.93 1.93
32 INT51051 IL1B Positive_regulation of Localization of IL6 7 0.57 3.79 1.87
33 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87
34 INT158302 Il23a Regulation of Gene_expression of Il17a 1 0.06 1.45 1.7
35 INT89379 TNF Positive_regulation of Gene_expression of IL6 5 0.50 4.37 1.69
36 INT215100 Binding of Hmgb1 and Tlr4 5 0.29 3.21 1.68
37 INT213071 IL6 Positive_regulation of Gene_expression of CRP 4 0.52 6.58 1.68
38 INT122428 Binding of Ighm and Prkci 1 0.00 0 1.66
39 INT24689 Binding of PLAT and Serpine1 1 0.00 3.77 1.64
40 INT79778 Tlr4 Positive_regulation of Localization of TNF 4 0.08 4.21 1.61
41 INT158774 Mapk14 Regulation of Il6 1 0.11 0.08 1.57
42 INT306745 Binding of Il12a and IL23A 1 0.10 3.25 1.56
43 INT254205 Binding of Myd88 and Tlr4 12 0.19 3.17 1.54
44 INT253863 Binding of LBP and PNP 1 0.13 1.5 1.5
45 INT126718 Binding of Il6 and Il6r 3 0.09 2.33 1.49
46 INT150885 Il6 Regulation of Il10 1 0.22 1.74 1.47
47 INT155371 VIP Positive_regulation of Localization of IL6 1 0.64 3.37 1.44
48 INT236365 Binding of CD40LG and IL6 3 0.20 4.16 1.42
49 INT172834 Binding of IL6 and T2dm2 1 0.00 6.4 1.4
50 INT223156 Il6 Regulation of A2m 1 0.11 2.79 1.39
51 INT56093 FGFR1 Regulation of Gene_expression of SERPINE1 1 0.23 1.71 1.37
52 INT218309 Binding of CRP and IL6 3 0.23 4.78 1.36
53 INT122430 Negative_regulation of Binding of Ighm and Prkci 1 0.00 0 1.36
54 INT160586 IL6 Positive_regulation of Gene_expression of OPRM1 1 0.14 0.54 1.35
55 INT56087 TNF Regulation of Gene_expression of SERPINE1 1 0.43 1.67 1.33
56 INT294775 IRF6 Positive_regulation of TLR4 6 0.08 2.04 1.32
57 INT136603 Calca Positive_regulation of Localization of Il6 1 0.67 0.78 1.32
58 INT78066 Tlr4 Positive_regulation of Localization of Il6 5 0.03 0.76 1.25
59 INT161507 Tlr4 Positive_regulation of Gene_expression of Il1b 1 0.24 0.19 1.25
60 INT186355 Il23a Positive_regulation of Gene_expression of Il17a 4 0.12 3 1.24
61 INT161508 Tlr4 Positive_regulation of Mapk14 2 0.19 0.46 1.24
62 INT121190 KCNMA1 Positive_regulation of Gene_expression of IL6 1 0.03 0.54 1.24
63 INT151648 TLR4 Regulation of Gene_expression of ICAM1 1 0.00 2.86 1.24
64 INT202040 CAMK2N2 Negative_regulation of MMP7 1 0.00 0.73 1.24
65 INT121189 KCNMA1 Positive_regulation of IL6 1 0.04 0.54 1.23
66 INT70033 IL6 Regulation of PRF1 1 0.03 1.42 1.21
67 INT329956 Binding of IL2 and IL23R 1 0.33 4.58 1.21
68 INT70047 IL6 Regulation of Negative_regulation of PRF1 1 0.03 1.42 1.21
69 INT70029 IL6 Regulation of Negative_regulation of IL10 1 0.05 1.42 1.21
70 INT161509 Tlr4 Positive_regulation of Mapk8 1 0.15 0.3 1.16
71 INT161510 Tlr4 Positive_regulation of Mapk1 1 0.14 0.3 1.16
72 INT185321 Tlr4 Positive_regulation of Gene_expression of Il6 5 0.14 1.97 1.15
73 INT94490 Il6 Positive_regulation of Gene_expression of Avp 1 0.33 1.97 1.15
74 INT94508 Il6 Positive_regulation of Gene_expression of AVP 1 0.42 1.96 1.14
75 INT89938 Tlr4 Positive_regulation of Gene_expression of TNF 6 0.25 1.3 1.12
76 INT94496 Il6 Positive_regulation of Gene_expression of Crh 1 0.29 1.94 1.12
77 INT294710 CRP Positive_regulation of Gene_expression of IL6 1 0.63 1.9 1.12
78 INT83616 Binding of IL6 and IL8 5 0.09 5.8 1.11
79 INT267588 IL10 Negative_regulation of Gene_expression of IL6 1 0.01 2.25 1.11
80 INT223154 Negative_regulation of Mapk14 Negative_regulation of Localization of Il6 1 0.19 1.13 1.11
81 INT223157 Abat Negative_regulation of Localization of Il6 1 0.05 1.13 1.1
82 INT333966 Binding of Il6r and Il6st 1 0.01 1.74 1.1
83 INT167426 Tlr4 Positive_regulation of Localization of Gpt 1 0.25 1.26 1.1
84 INT130656 Tlr4 Positive_regulation of Cyba 1 0.00 0.05 1.09
85 INT94495 Tnf Positive_regulation of Gene_expression of Il6 1 0.30 1.9 1.09
86 INT130657 Negative_regulation of Tlr4 Positive_regulation of Cyba 1 0.00 0.05 1.09
87 INT57986 Il1b Regulation of Positive_regulation of Il6 2 0.39 0.23 1.05
88 INT120316 Ghrh Regulation of Il6 1 0.11 0.95 1.05
89 INT120310 Ghrh Regulation of Positive_regulation of Il6 1 0.18 0.95 1.05
90 INT182125 Binding of CD14 and TLR4 7 0.25 3.78 1.03
91 INT88875 Ifng Positive_regulation of Transcription of Nos2 1 0.02 0.27 1.03
92 INT61617 PTGER2 Regulation of Gene_expression of IL6 3 0.11 1.13 1.02
93 INT87025 ZAK Positive_regulation of Gene_expression of IL6 2 0.11 1.59 1.02
94 INT122429 Prkci Regulation of Gene_expression of Ighm 1 0.00 0 1.02
95 INT122431 Prkci Negative_regulation of Negative_regulation of Ighm 1 0.00 0 1.02
96 INT218310 IL6 Positive_regulation of Localization of CRP 1 0.29 3.33 1.02
97 INT122433 Prkci Negative_regulation of Ighm 1 0.00 0 1.02
98 INT88887 IRF6 Positive_regulation of Transcription of Nos2 1 0.21 0.27 1.02
99 INT206074 Binding of IL6 and IL6ST 7 0.32 3.79 1.01
100 INT88874 Ifng Regulation of Nos2 1 0.01 0.26 1.01
101 INT174910 Binding of LBP and IFIH1 1 0.04 1.01 1.01
102 INT88884 IRF6 Regulation of Nos2 1 0.12 0.26 1
103 INT88886 IRF6 Positive_regulation of Nos2 1 0.22 0.26 1
104 INT278946 IL6 Regulation of Gene_expression of IL8 1 0.20 1.9 1
105 INT88888 Regulation of IRF6 Positive_regulation of Nos2 1 0.20 0.26 1
106 INT86181 SFTPA1 Positive_regulation of IL6 1 0.07 0.32 0.99
107 INT244133 DDB1 Positive_regulation of Gene_expression of IL6 1 0.01 1.91 0.99
108 INT317584 Binding of Lbp and Pgp 1 0.24 1.08 0.99
109 INT154254 Tnf Positive_regulation of Il6 1 0.36 0.94 0.97
110 INT114320 TNF Positive_regulation of Gene_expression of Il6 1 0.07 1.73 0.97
111 INT163390 Il6 Positive_regulation of Gene_expression of Crp 2 0.03 3.42 0.95
112 INT299988 IL6 Positive_regulation of Localization of IL8 1 0.05 0.81 0.94
113 INT145163 Tlr4 Positive_regulation of Localization of Nsfl1c 1 0.02 0.43 0.94
114 INT285418 IRF6 Positive_regulation of Localization of IL6 3 0.05 0.66 0.93
115 INT285561 Il23a Positive_regulation of Gene_expression of Il22 2 0.06 2.45 0.93
116 INT219154 Binding of HMGB1 and TLR4 2 0.17 4.45 0.93
117 INT336017 Vip Regulation of Tlr4 1 0.22 1.23 0.93
118 INT134785 Il2rb Regulation of Gene_expression of IL6 1 0.00 1.16 0.92
119 INT134784 Il2rb Regulation of IL6 1 0.00 1.16 0.92
120 INT161455 Mmp7 Positive_regulation of Egfr 1 0.03 0.19 0.92
121 INT306327 Binding of Ly96 and Tlr4 1 0.10 1.83 0.91
122 INT343909 IgG Positive_regulation of Gene_expression of TLR4 1 0.04 3.49 0.91
123 INT221386 Tlr4 Positive_regulation of Gene_expression of IL8 6 0.14 3.53 0.9
124 INT78062 Il1a Positive_regulation of Localization of Il6 3 0.24 0.48 0.9
125 INT64717 Pomc Positive_regulation of Il6 1 0.13 0.19 0.9
126 INT120147 Tlr4 Positive_regulation of Tnf 3 0.39 2.14 0.89
127 INT168281 Tlr4 Positive_regulation of Phosphorylation of Mapk4 1 0.06 1.05 0.89
128 INT108687 Nfkb1 Regulation of Positive_regulation of Nos2 1 0.50 1.28 0.88
129 INT159962 Rock2 Regulation of Localization of Il6 1 0.09 2.7 0.88
130 INT108686 Nfkb1 Regulation of Nos2 1 0.69 1.27 0.88
131 INT231716 Binding of IL6 and DIP 1 0.24 1.55 0.87
132 INT199492 Il6 Positive_regulation of Transcription of Oprm1 1 0.01 0.81 0.86
133 INT199487 Il6 Positive_regulation of Oprm1 1 0.01 0.8 0.86
134 INT199491 Il6 Positive_regulation of Positive_regulation of Il6 1 0.00 0.81 0.86
135 INT244323 Csf2 Positive_regulation of Gene_expression of Tlr4 1 0.23 1.93 0.85
136 INT342986 PTAFR Positive_regulation of Gene_expression of IL6 1 0.14 0.39 0.84
137 INT54992 Il6 Negative_regulation of Prl 1 0.00 0.86 0.84
138 INT105435 TNF Positive_regulation of IL6 5 0.25 4.45 0.83
139 INT184114 Tlr4 Positive_regulation of Socs3 2 0.65 1.14 0.83
140 INT86430 IL6 Positive_regulation of Gene_expression of HP 1 0.15 3.61 0.83
141 INT195217 EGFL7 Negative_regulation of Gene_expression of IL6 1 0.06 1.14 0.83
142 INT102931 Nos3 Positive_regulation of Nos2 1 0.43 1.63 0.83
143 INT342999 IL6 Positive_regulation of Gene_expression of HIST2H2AA3 1 0.00 0.4 0.83
144 INT152236 Tlr4 Regulation of Gene_expression of Nos2 3 0.19 0.64 0.82
145 INT185937 NOS2 Regulation of Prkaca 1 0.03 1.08 0.82
146 INT88885 IRF6 Positive_regulation of Gene_expression of Nos2 1 0.21 0.1 0.81
147 INT88878 Negative_regulation of Nfkb1 Positive_regulation of Gene_expression of Nos2 1 0.06 0.1 0.81
148 INT53199 Positive_regulation of Cd4 Positive_regulation of Gene_expression of Il2 1 0.52 0.72 0.8
149 INT306271 IL1A Positive_regulation of Gene_expression of IL6 1 0.30 0.85 0.8
150 INT96501 Il11 Regulation of Gene_expression of NOS2 1 0.00 1.04 0.8
151 INT140921 Btnl2 Negative_regulation of Cd4 1 0.01 0.88 0.8
152 INT223753 Tlr4 Positive_regulation of Gene_expression of Il10 4 0.32 1.93 0.78
153 INT209043 Binding of Fn1 and Slc11a1 3 0.03 1.91 0.78
154 INT196577 Negative_regulation of Mapk14 Negative_regulation of Il6 1 0.13 0.45 0.78
155 INT152235 Mapk8 Positive_regulation of Localization of Tlr4 1 0.38 0.26 0.78
156 INT196574 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Il6 1 0.13 0.45 0.78
157 INT339495 Tlr4 Positive_regulation of Eif2ak2 1 0.21 0.58 0.77
158 INT194644 Tlr4 Positive_regulation of TNF 6 0.58 2.42 0.76
159 INT348174 Binding of STAT3 and IL23R 1 0.40 1.9 0.76
160 INT178579 CNTN2 Positive_regulation of IL6 1 0.07 2.17 0.75
161 INT128815 Mapk14 Regulation of Gene_expression of Nos2 1 0.21 0.46 0.74
162 INT128813 Mapk8 Regulation of Gene_expression of Nos2 1 0.23 0.46 0.74
163 INT284306 Tlr4 Positive_regulation of Adrb3 1 0.00 1.19 0.74
164 INT142847 IRF6 Positive_regulation of IL6 5 0.07 1.09 0.73
165 INT248271 IL6 Regulation of Gene_expression of Crp 3 0.27 1.7 0.73
166 INT124352 Il6 Positive_regulation of Positive_regulation of Gorasp2 1 0.10 1.19 0.73
167 INT327994 Il6 Positive_regulation of Gene_expression of ROS1 1 0.05 0.55 0.73
168 INT172134 Binding of IL6 and IL15 2 0.01 1.18 0.72
169 INT209029 Il12b Positive_regulation of Elf1 1 0.24 0.37 0.72
170 INT317585 Binding of Lbp and Ppap2b 1 0.03 0.78 0.72
171 INT209031 Il12b Positive_regulation of Ccr1 1 0.02 0.37 0.72
172 INT209030 Il12b Positive_regulation of Cxcl1 1 0.16 0.37 0.72
173 INT209028 Il12b Positive_regulation of Il17a 1 0.12 0.37 0.72
174 INT150996 Sfpq Positive_regulation of Gene_expression of Il6 1 0.04 0.7 0.72
175 INT236364 CD40LG Positive_regulation of Gene_expression of IL6 1 0.25 1.37 0.72
176 INT51005 PDYN Positive_regulation of IL6 1 0.08 0.84 0.72
177 INT209032 Il12b Positive_regulation of Csf2 1 0.08 0.37 0.72
178 INT222432 Binding of Tlr4 and Cd14 1 0.02 0.74 0.71
179 INT159963 Tnf Positive_regulation of Localization of Il6 1 0.12 2.32 0.71
180 INT89936 Tlr4 Positive_regulation of Il6 3 0.49 0.95 0.7
181 INT91700 Il6 Negative_regulation of Oprd1 1 0.23 0 0.7
182 INT346267 Binding of HGF and IL6 1 0.04 0.96 0.7
183 INT187522 ATIC Negative_regulation of Gene_expression of Nos2 1 0.02 1.46 0.7
184 INT215098 Tlr4 Positive_regulation of Localization of Il6 3 0.18 1.18 0.69
185 INT280951 Tlr4 Positive_regulation of Localization of S100a8 1 0.01 1.09 0.69
186 INT278968 LEP Regulation of Gene_expression of IL6 1 0.29 1.11 0.69
187 INT150998 Sfpq Negative_regulation of Gene_expression of Il6 1 0.05 0.69 0.69
188 INT185802 Binding of MMP7 and SPP1 1 0.33 1.71 0.68
189 INT215093 Tlr4 Positive_regulation of Localization of Hmgb1 1 0.32 2.9 0.68
190 INT203758 Binding of IL6 and TNF 3 0.26 2.03 0.67
191 INT278953 IL6 Regulation of Gene_expression of PTGER2 1 0.04 1.38 0.67
192 INT164782 Il6 Regulation of Gene_expression of Cx3cr1 1 0.27 0.79 0.67
193 INT278965 LEP Positive_regulation of Gene_expression of NOS2 2 0.29 2.12 0.66
194 INT320152 IL6 Positive_regulation of IL1RN 2 0.23 2.59 0.66
195 INT130355 spc Regulation of Serpine1 1 0.14 0.2 0.66
196 INT306020 Binding of LBP and Tlr4 1 0.13 0.34 0.66
197 INT120144 Negative_regulation of Tlr4 Positive_regulation of Tnf 1 0.18 0.91 0.66
198 INT220035 Nos1 Positive_regulation of Nos2 1 0.29 0.45 0.66
199 INT130354 Adcy10 Regulation of Serpine1 1 0.17 0.2 0.66
200 INT343851 Positive_regulation of Binding of IRF6 and TLR4 1 0.07 1.96 0.66

Single Events

The table below shows the top 100 pain related interactions that have been reported for defense response to Gram-negative bacterium. They are ordered first by their pain relevance and then by number of times they were reported in defense response to Gram-negative bacterium. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22
2 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57
3 INT48955 Gene_expression of Nos2 753 0.78 403.87 208.08
4 INT11313 Positive_regulation of Il6 526 0.70 331.27 201.59
5 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38
6 INT48953 Positive_regulation of Nos2 486 0.70 239.85 131.87
7 INT7533 Gene_expression of Tlr4 720 0.78 343.22 121.57
8 INT1026 Binding of Lbp 207 0.48 150.96 119.16
9 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3
10 INT12082 Localization of IL6 365 0.81 241.78 105.78
11 INT64636 Positive_regulation of Gene_expression of Nos2 242 0.70 147.52 79.53
12 INT19511 Localization of Il6 212 0.81 118.17 67.67
13 INT9664 Binding of LBP 127 0.48 94.9 63.42
14 INT1951 Positive_regulation of Tlr4 345 0.70 176.99 62.42
15 INT10706 Regulation of Il6 150 0.62 93.23 62.34
16 INT48901 Negative_regulation of IL6 186 0.57 136.33 57.87
17 INT117223 Gene_expression of TLR4 348 0.78 206.18 54.42
18 INT1027 Gene_expression of Lbp 132 0.77 106.7 54.16
19 INT49993 Positive_regulation of Gene_expression of Il6 149 0.70 88.07 53.78
20 INT48952 Negative_regulation of Nos2 204 0.59 101.73 53.15
21 INT9234 Negative_regulation of Gene_expression of IL6 171 0.59 101.61 53.15
22 INT49017 Negative_regulation of Gene_expression of Nos2 169 0.59 80.64 52.67
23 INT9210 Regulation of IL6 166 0.62 125.61 49.95
24 INT1028 Positive_regulation of Lbp 102 0.69 67.86 46.05
25 INT50957 Negative_regulation of Il6 134 0.59 79.08 42.67
26 INT9372 Negative_regulation of Lbp 86 0.58 46.54 41.71
27 INT9239 Regulation of Gene_expression of IL6 106 0.61 75.24 36.53
28 INT79060 Gene_expression of NOS2 116 0.78 69.25 34.84
29 INT49214 Gene_expression of Cd4 269 0.78 154.22 34.05
30 INT81289 Positive_regulation of Gene_expression of Tlr4 192 0.69 104.5 33.89
31 INT19759 Gene_expression of LBP 77 0.77 56.44 33.23
32 INT56809 Binding of Tlr4 184 0.48 106.02 31.18
33 INT56290 Negative_regulation of Gene_expression of Il6 79 0.59 47.98 31.07
34 INT50230 Positive_regulation of Localization of IL6 105 0.70 69.21 29.52
35 INT86437 Binding of IL6 154 0.48 121.22 29.3
36 INT118734 Gene_expression of Tlr4 70 0.78 55.7 28.19
37 INT11361 Gene_expression of SERPINE1 183 0.78 136.45 27.97
38 INT78251 Positive_regulation of LBP 38 0.69 39.98 26.73
39 INT135411 Gene_expression of Il23a 76 0.72 72.87 26.15
40 INT9088 Negative_regulation of LBP 48 0.58 33.06 25.89
41 INT61953 Transcription of Nos2 101 0.72 46.64 25.49
42 INT1030 Localization of Lbp 52 0.74 38.92 24.91
43 INT70503 Regulation of Gene_expression of Nos2 71 0.62 44 24.01
44 INT79061 Positive_regulation of NOS2 92 0.65 58.89 23.96
45 INT134651 Binding of TLR4 89 0.48 66.96 23.19
46 INT78057 Localization of Tlr4 140 0.77 67.75 21.72
47 INT7535 Negative_regulation of Tlr4 111 0.56 56.84 21.37
48 INT51474 Binding of Il6 55 0.48 44.99 20.52
49 INT51054 Negative_regulation of Localization of IL6 45 0.59 24.48 18.97
50 INT52179 Regulation of Lbp 39 0.61 25.4 18.32
51 INT61626 Transcription of IL6 73 0.72 42.04 17.86
52 INT168263 Gene_expression of IL23A 57 0.58 47.1 17.67
53 INT117220 Positive_regulation of TLR4 64 0.69 53.61 17.33
54 INT61949 Regulation of Nos2 74 0.58 34.08 16.7
55 INT22900 Positive_regulation of Cd4 126 0.67 82.77 16.43
56 INT50932 Positive_regulation of Positive_regulation of Il6 36 0.69 24.9 16.12
57 INT43906 Regulation of Tlr4 71 0.53 35.18 15.49
58 INT49532 Regulation of Gene_expression of Il6 43 0.61 25.8 14.99
59 INT11636 Positive_regulation of SERPINE1 85 0.69 68.73 14.8
60 INT67641 Negative_regulation of Gene_expression of Tlr4 90 0.58 46 14.6
61 INT151120 Negative_regulation of Tlr4 18 0.59 21.09 14.46
62 INT3796 Gene_expression of Ighm 130 0.77 69.61 13.78
63 INT15684 Positive_regulation of Serpine1 65 0.70 43.51 13.67
64 INT55256 Negative_regulation of Localization of Il6 38 0.58 16.12 13.67
65 INT15921 Positive_regulation of Serpine1 85 0.68 81.24 13.4
66 INT117222 Positive_regulation of Gene_expression of TLR4 80 0.70 51.6 12.9
67 INT55255 Positive_regulation of Localization of Il6 48 0.69 24.88 12.76
68 INT52905 Gene_expression of Cd4 84 0.78 45.68 12.75
69 INT20102 Gene_expression of Serpine1 102 0.78 65.99 12.61
70 INT12084 Regulation of Localization of IL6 36 0.61 20.32 12.34
71 INT49142 Gene_expression of SELP 94 0.75 54.61 11.64
72 INT50933 Transcription of Il6 38 0.72 24.31 11.58
73 INT95369 Positive_regulation of Gene_expression of NOS2 36 0.55 25.09 11.37
74 INT49396 Negative_regulation of Positive_regulation of Il6 29 0.59 16.39 11.31
75 INT48956 Negative_regulation of Positive_regulation of Nos2 34 0.46 13.15 11.15
76 INT118742 Positive_regulation of Tlr4 32 0.69 27.55 11.09
77 INT133172 Gene_expression of Il12b 98 0.75 52.16 10.68
78 INT57000 Localization of LBP 21 0.78 11.01 10.01
79 INT2378 Negative_regulation of SERPINE1 47 0.59 34.55 9.9
80 INT70850 Positive_regulation of Transcription of Nos2 30 0.70 18.95 9.68
81 INT11047 Positive_regulation of Positive_regulation of IL6 45 0.66 28.7 9.37
82 INT226463 Positive_regulation of IL23A 23 0.45 21.58 9.18
83 INT32624 Regulation of LBP 15 0.60 11.48 8.71
84 INT146991 Positive_regulation of Gene_expression of Tlr4 21 0.69 20.76 8.69
85 INT73234 Positive_regulation of Lbp 13 0.69 12.55 8.57
86 INT19185 Negative_regulation of Cd4 80 0.51 61.32 8.51
87 INT72337 Positive_regulation of Positive_regulation of Nos2 37 0.65 17.02 8.11
88 INT15918 Gene_expression of Serpine1 60 0.62 41.73 7.72
89 INT74629 Gene_expression of Mmp7 17 0.55 12.78 7.58
90 INT131359 Positive_regulation of Gene_expression of Cd4 40 0.58 22.43 7.53
91 INT1952 Negative_regulation of Positive_regulation of Tlr4 33 0.51 15.8 7.41
92 INT1950 Positive_regulation of Positive_regulation of Tlr4 38 0.49 20.17 7.14
93 INT213886 Binding of IL23R 7 0.46 16.79 6.94
94 INT295467 Negative_regulation of Gene_expression of Tlr4 11 0.58 7.94 6.83
95 INT160562 Localization of Cd4 49 0.71 27.58 6.78
96 INT50255 Regulation of Cd4 39 0.49 29.73 6.77
97 INT13139 Negative_regulation of Cd4 27 0.47 17.49 6.61
98 INT7376 Positive_regulation of CAMP 17 0.67 6.39 6.6
99 INT89131 Negative_regulation of NOS2 20 0.58 9.68 6.56
100 INT3795 Positive_regulation of Ighm 46 0.68 22.43 6.47
101 INT150023 Positive_regulation of Il23a 25 0.38 18.33 6.32
102 INT88245 Gene_expression of Slc11a1 42 0.53 18.86 6.2
103 INT183910 Negative_regulation of Gene_expression of Lbp 10 0.35 9.78 6.15
104 INT97797 Localization of TLR4 18 0.77 13.78 6
105 INT64724 Positive_regulation of Transcription of IL6 26 0.69 13.63 5.96
106 INT103760 Regulation of Gene_expression of Tlr4 35 0.59 16.26 5.95
107 INT53196 Binding of Cd4 44 0.47 27.28 5.85
108 INT143158 Negative_regulation of Gene_expression of TLR4 31 0.56 20.62 5.69
109 INT94428 Negative_regulation of Gene_expression of NOS2 20 0.47 11.61 5.62
110 INT11360 Localization of SERPINE1 41 0.80 33.98 5.61
111 INT168279 Regulation of Tlr4 17 0.54 8.97 5.5
112 INT21956 Negative_regulation of Mmp7 12 0.34 7.32 5.34
113 INT64716 Regulation of Positive_regulation of Il6 7 0.54 2.83 5.34
114 INT49801 Positive_regulation of SELP 21 0.48 21.34 5.25
115 INT145767 Negative_regulation of TLR4 18 0.43 11.03 5.25
116 INT64723 Regulation of Positive_regulation of IL6 13 0.61 12.59 5.19
117 INT1029 Positive_regulation of Gene_expression of Lbp 17 0.50 11.03 5.18
118 INT157622 Positive_regulation of Localization of Tlr4 34 0.48 22.63 5.09
119 INT95131 Binding of Cd4 27 0.37 21.62 5.07
120 INT73608 Localization of Nos2 21 0.75 9.58 5.05
121 INT175312 Positive_regulation of Gene_expression of IL23A 17 0.45 14.8 5.05
122 INT15941 Negative_regulation of Serpine1 42 0.58 21.07 4.95
123 INT89132 Regulation of NOS2 9 0.61 7.34 4.95
124 INT15920 Regulation of Serpine1 34 0.42 17.36 4.89
125 INT61950 Regulation of Positive_regulation of Nos2 17 0.43 9.01 4.87
126 INT26583 Positive_regulation of Cd4 40 0.54 21.96 4.83
127 INT5917 Negative_regulation of CAMP 7 0.42 1.07 4.63
128 INT11106 Gene_expression of Lbp 10 0.67 10.29 4.52
129 INT204783 Positive_regulation of Gene_expression of Il23a 17 0.36 15.53 4.42
130 INT11354 Regulation of Gene_expression of SERPINE1 11 0.61 8.66 4.42
131 INT52133 Regulation of Localization of Il6 7 0.61 5.35 4.37
132 INT94427 Positive_regulation of Positive_regulation of NOS2 14 0.47 11.15 4.3
133 INT11635 Positive_regulation of Gene_expression of SERPINE1 35 0.68 24.57 4.26
134 INT11634 Regulation of SERPINE1 24 0.62 20.06 4.26
135 INT89784 Regulation of Transcription of Nos2 14 0.42 8.39 4.24
136 INT79413 Gene_expression of CAMP 13 0.75 8.3 4.02
137 INT17548 Negative_regulation of Serpine1 30 0.57 24.69 3.93
138 INT92653 Gene_expression of IL12B 21 0.75 17.28 3.89
139 INT209018 Positive_regulation of Slc11a1 11 0.55 7.12 3.83
140 INT186808 Transcription of TLR4 22 0.69 12.77 3.73
141 INT36799 Negative_regulation of Ighm 21 0.41 17.47 3.65
142 INT144231 Gene_expression of Il12b 18 0.75 12.93 3.65
143 INT90406 Gene_expression of IL6R 27 0.38 15.74 3.64
144 INT133169 Positive_regulation of Il12b 25 0.49 13 3.64
145 INT174816 Binding of IL6R 14 0.09 11.26 3.63
146 INT133733 Positive_regulation of Localization of Lbp 6 0.43 9.19 3.61
147 INT16263 Regulation of Serpine1 13 0.45 5.24 3.6
148 INT143159 Regulation of Gene_expression of TLR4 28 0.62 15.08 3.54
149 INT64725 Regulation of Transcription of IL6 9 0.45 7.96 3.49
150 INT11101 Regulation of Gene_expression of Lbp 6 0.61 5.43 3.49
151 INT63425 Positive_regulation of Gene_expression of SELP 23 0.67 15.34 3.48
152 INT11107 Binding of Lbp 12 0.42 4.42 3.41
153 INT81403 Positive_regulation of Regulation of Il6 4 0.44 1.81 3.37
154 INT64715 Phosphorylation of Il6 7 0.81 4.24 3.36
155 INT61952 Negative_regulation of Transcription of Nos2 17 0.54 5.1 3.34
156 INT192298 Negative_regulation of MMP7 7 0.27 3.71 3.29
157 INT126223 Binding of Nos2 17 0.37 6 3.22
158 INT178711 Protein_catabolism of Tlr4 15 0.84 6.75 3.19
159 INT250884 Binding of IL23A 5 0.19 7.17 3.17
160 INT163269 Binding of Il23a 11 0.44 7.2 3.14
161 INT82444 Positive_regulation of Gene_expression of Cd4 10 0.47 4.36 3.12
162 INT126716 Positive_regulation of Il6r 8 0.42 4.31 3.1
163 INT94947 Positive_regulation of Transcription of Il6 9 0.67 6.91 3.04
164 INT145768 Regulation of TLR4 19 0.45 8.31 2.96
165 INT59719 Localization of SELP 12 0.78 8.4 2.95
166 INT105783 Protein_catabolism of IL6 7 0.48 4.72 2.95
167 INT102233 Gene_expression of MMP7 40 0.76 15.78 2.93
168 INT185315 Transcription of Tlr4 24 0.69 8.65 2.93
169 INT89133 Transcription of NOS2 13 0.71 6.84 2.93
170 INT133174 Positive_regulation of Gene_expression of Il12b 29 0.15 13.04 2.92
171 INT178108 Positive_regulation of MMP7 11 0.56 7.31 2.85
172 INT72757 Negative_regulation of Negative_regulation of Nos2 8 0.42 4.23 2.68
173 INT64714 Positive_regulation of Phosphorylation of Il6 4 0.50 3.22 2.67
174 INT100086 Negative_regulation of Localization of Tlr4 15 0.37 5.92 2.47
175 INT79609 Positive_regulation of Negative_regulation of Nos2 5 0.49 3.6 2.43
176 INT22679 Binding of SERPINE1 25 0.36 17.33 2.36
177 INT76094 Localization of NOS2 8 0.72 2.76 2.34
178 INT209019 Localization of Slc11a1 12 0.33 4.33 2.33
179 INT10558 Regulation of Regulation of IL6 6 0.45 4.94 2.33
180 INT333961 Binding of Il6r 1 0.07 3.67 2.29
181 INT74628 Positive_regulation of Mmp7 8 0.25 4.19 2.27
182 INT92648 Positive_regulation of IL12B 7 0.20 4.55 2.19
183 INT209027 Positive_regulation of Positive_regulation of Slc11a1 3 0.14 2.41 2.18
184 INT15922 Positive_regulation of Positive_regulation of Serpine1 6 0.31 8.34 2.16
185 INT250888 Negative_regulation of IL23A 4 0.30 6.13 2.15
186 INT58469 Negative_regulation of Positive_regulation of IL6 16 0.42 8.1 2.14
187 INT96841 Regulation of Slc11a1 9 0.36 6.83 2.14
188 INT89130 Positive_regulation of Transcription of NOS2 7 0.50 3.32 2.14
189 INT228889 Protein_catabolism of LBP 4 0.77 5.14 2.13
190 INT17747 Regulation of Cd4 14 0.41 10.02 2.12
191 INT178799 Positive_regulation of Camp 8 0.43 4.37 2.1
192 INT74156 Positive_regulation of Il12b 3 0.49 1.54 2.04
193 INT3797 Positive_regulation of Gene_expression of Ighm 16 0.47 9.4 2.01
194 INT222609 Binding of Tlr4 8 0.43 4.03 1.98
195 INT71115 Positive_regulation of Gene_expression of Serpine1 20 0.70 15.32 1.97
196 INT23188 Localization of Serpine1 22 0.79 16.06 1.96
197 INT258780 Regulation of Il23a 6 0.13 4.77 1.96
198 INT92056 Transcription of Il12b 8 0.69 4.75 1.95
199 INT326816 Negative_regulation of Positive_regulation of Tlr4 2 0.59 3.96 1.95
200 INT114317 Gene_expression of Il6r 9 0.54 3.4 1.89
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