GO:0050847

From wiki-pain
Jump to: navigation, search
Name progesterone receptor signaling pathway
Categary Process
Go Slim No
Go Link GO:0050847
Unique Molecular Interactions 60
Total Molecular Interactions 78
Total Single Events 765
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for progesterone receptor signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported for progesterone receptor signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT231027 LOC100366054 Negative_regulation of Gene_expression of Pgr 1 0.02 0 0.62
2 INT310701 RPLP0 Regulation of Positive_regulation of PGR 1 0.01 0.49 0.53
3 INT231034 Sec22b Positive_regulation of Gene_expression of Pgr 1 0.04 0.09 0.53
4 INT168699 Binding of Nedd4 and Tyr 1 0.02 0.45 0.46
5 INT197591 Esr1 Regulation of Pgr 1 0.04 0 0.38
6 INT265015 Pgr Positive_regulation of Sds 1 0.04 0.49 0.37
7 INT245328 Binding of Esr2 and Pgr 1 0.03 0.41 0.37
8 INT266766 Binding of PGR and GOPC 1 0.00 1.08 0.29
9 INT71904 Binding of ESR1 and PGR 6 0.34 3.79 0.27
10 INT103279 PGR Negative_regulation of Gene_expression of CCL5 1 0.32 0.31 0.27
11 INT103280 PGR Negative_regulation of Positive_regulation of ATF4 1 0.02 0.31 0.26
12 INT310700 PGR Regulation of Gene_expression of RPLP0 1 0.01 0.37 0.25
13 INT197590 Esr2 Positive_regulation of Negative_regulation of Pgr 1 0.16 0 0.24
14 INT63193 POMC Positive_regulation of PGR 1 0.17 0.3 0.23
15 INT63199 INS Positive_regulation of PGR 1 0.11 0.3 0.23
16 INT63194 PTH Positive_regulation of PGR 1 0.25 0.29 0.22
17 INT35151 PLOD1 Regulation of PGR 1 0.09 0 0.21
18 INT35152 GH1 Regulation of PGR 1 0.08 0 0.21
19 INT35156 FSHR Regulation of PGR 1 0.18 0 0.21
20 INT159132 Klf9 Positive_regulation of Smc5 1 0.01 0.48 0.2
21 INT222300 Binding of ERBB2 and PGR 2 0.34 1.89 0.17
22 INT201865 Binding of PGR and NCOA1 1 0.03 0 0.17
23 INT168700 Positive_regulation of Binding of Nedd4 and Tyr 1 0.03 0.19 0.17
24 INT18043 Binding of SIGMAR1 and Pgr 1 0.00 0.06 0.16
25 INT201867 Binding of PGR and PASK 1 0.02 0.23 0.14
26 INT201618 Uvbi1 Positive_regulation of Phb 1 0.04 0.28 0.09
27 INT341825 Binding of TNC and PGR 1 0.14 0.63 0.09
28 INT287174 Binding of PGR and SHBG 1 0.18 0.11 0.08
29 INT38188 PGR Positive_regulation of Gene_expression of ESR1 1 0.42 0.22 0.07
30 INT201866 Binding of AR and PGR 1 0.07 0.34 0.06
31 INT197586 Esr2 Regulation of Pgr 1 0.09 0 0.06
32 INT187388 Esr2 Positive_regulation of Gene_expression of Pgr 1 0.00 0.8 0.03
33 INT199975 ESR1 Positive_regulation of PGR 1 0.05 0.11 0
34 INT197615 Esr1 Regulation of Gene_expression of Pgr 1 0.01 0.21 0
35 INT99770 Thbs1 Regulation of PGR 1 0.01 0 0
36 INT208017 Col4a4 Regulation of Gene_expression of Pgr 1 0.04 0.69 0
37 INT218973 Gen1 Regulation of Gene_expression of Pgr 1 0.06 0.09 0
38 INT313596 ESR1 Positive_regulation of Gene_expression of PGR 1 0.05 1 0
39 INT314687 ESR1 Regulation of PGR 1 0.27 0.88 0
40 INT99768 Oxtr Regulation of PGR 1 0.20 0 0
41 INT329013 Binding of LITAF and Nedd4 1 0.15 1.4 0
42 INT197614 Esr1 Regulation of Pgr 1 0.01 0.07 0
43 INT191166 Regulation of DBT Positive_regulation of PGR 1 0.01 0 0
44 INT329012 Binding of MPZ and Nedd4 1 0.03 0.7 0
45 INT197912 Dlst Positive_regulation of Gene_expression of Pgr 1 0.01 0.34 0
46 INT99772 Pgr Regulation of THBS1 1 0.00 0 0
47 INT191169 DBT Positive_regulation of PGR 1 0.02 0 0
48 INT191170 DBT Positive_regulation of Positive_regulation of PGR 1 0.02 0 0
49 INT197676 ESR1 Regulation of Gene_expression of Pgr 1 0.06 0.1 0
50 INT325285 COMP Positive_regulation of UBR5 1 0.00 2.9 0
51 INT197588 Dlat Regulation of Pgr 1 0.04 0.26 0
52 INT201799 PGR Regulation of HSD17B2 1 0.12 0.08 0
53 INT97181 Tm2d1 Positive_regulation of Transcription of Pgr 1 0.06 0 0
54 INT178628 Igf1 Regulation of Gene_expression of Pgr 1 0.24 0.19 0
55 INT197595 Ppt1 Regulation of Pgr 1 0.08 0.26 0
56 INT186023 Binding of PCA and PGR 1 0.06 0.28 0
57 INT341792 Binding of PLAU and Pgr 1 0.02 0.34 0
58 INT99773 Pgr Regulation of PGR 1 0.02 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for progesterone receptor signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported in progesterone receptor signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT2386 Gene_expression of Pgr 112 0.78 45.46 22.19
2 INT27242 Gene_expression of PGR 153 0.75 98.77 12.79
3 INT96218 Positive_regulation of Pgr 17 0.68 5.23 6.57
4 INT37652 Positive_regulation of Pgr 29 0.59 9.09 4.67
5 INT88947 Positive_regulation of Gene_expression of Pgr 22 0.64 7 4.39
6 INT57252 Negative_regulation of PGR 22 0.43 12.95 3.33
7 INT10353 Positive_regulation of PGR 34 0.70 21.84 3.28
8 INT132760 Gene_expression of Pgr 47 0.66 28.17 2.85
9 INT136105 Regulation of Pgr 4 0.45 1.93 2.62
10 INT34830 Regulation of PGR 14 0.45 6.99 2.32
11 INT22605 Regulation of Pgr 22 0.62 7.1 2.26
12 INT178632 Regulation of Gene_expression of Pgr 11 0.35 1.56 2.26
13 INT83236 Localization of PGR 14 0.73 8.26 2.23
14 INT13267 Binding of Pgr 15 0.40 3.5 2.22
15 INT68496 Binding of PGR 26 0.48 16.36 2.09
16 INT93886 Positive_regulation of Gene_expression of PGR 19 0.52 15.78 1.89
17 INT96216 Negative_regulation of Positive_regulation of Pgr 2 0.37 0.74 1.72
18 INT132761 Negative_regulation of Pgr 6 0.50 3.07 1.58
19 INT45711 Localization of Pgr 7 0.61 1.27 1.56
20 INT27938 Negative_regulation of Pgr 12 0.38 1.98 1.05
21 INT172529 Negative_regulation of Gene_expression of PGR 24 0.48 16.69 1.04
22 INT158737 Localization of Pgr 4 0.10 1.24 0.98
23 INT178633 Negative_regulation of Gene_expression of Pgr 2 0.21 0.26 0.86
24 INT147493 Phosphorylation of Pgr 1 0.69 1.4 0.72
25 INT132759 Positive_regulation of Gene_expression of Pgr 9 0.38 5.12 0.64
26 INT158738 Binding of Pgr 9 0.28 3.49 0.61
27 INT147492 Negative_regulation of Gene_expression of Pgr 2 0.50 0.98 0.49
28 INT140949 Positive_regulation of Positive_regulation of Pgr 4 0.59 1.23 0.42
29 INT202189 Transcription of PGR 5 0.51 0.8 0.4
30 INT168697 Binding of Nedd4 1 0.26 0.48 0.38
31 INT158739 Positive_regulation of Localization of Pgr 1 0.07 0.36 0.36
32 INT97179 Transcription of Pgr 17 0.67 4.54 0.3
33 INT197602 Negative_regulation of Transcription of Pgr 1 0.25 0.09 0.24
34 INT300941 Regulation of Localization of PGR 1 0.04 1.02 0.24
35 INT306713 Regulation of Positive_regulation of Pgr 1 0.06 0.39 0.24
36 INT92079 Negative_regulation of Binding of Pgr 1 0.34 0 0.22
37 INT168693 Negative_regulation of Binding of Nedd4 1 0.31 0.29 0.21
38 INT168696 Positive_regulation of Binding of Nedd4 1 0.34 0.29 0.21
39 INT257540 Transcription of Pgr 2 0.04 0.82 0.16
40 INT71905 Regulation of Gene_expression of PGR 6 0.50 1.3 0.14
41 INT208015 Positive_regulation of Positive_regulation of Pgr 2 0.35 0.96 0.13
42 INT257541 Positive_regulation of Transcription of Pgr 1 0.03 0.22 0.13
43 INT344066 Positive_regulation of Binding of PGR 1 0.03 0.63 0.12
44 INT294171 Regulation of Gene_expression of Pgr 2 0.15 0.93 0.1
45 INT209177 Positive_regulation of Transcription of PGR 1 0.50 0.05 0.07
46 INT197611 Regulation of Regulation of Pgr 1 0.16 0 0.06
47 INT312983 Protein_catabolism of PGR 1 0.11 0.9 0.04
48 INT27939 Positive_regulation of Negative_regulation of Pgr 6 0.27 1.44 0
49 INT97180 Regulation of Transcription of Pgr 5 0.38 2.2 0
50 INT218972 Positive_regulation of Binding of Pgr 2 0.28 0.46 0
51 INT197609 Positive_regulation of Transcription of Pgr 1 0.29 0.07 0
52 INT243078 Gene_expression of Phb 1 0.42 0.09 0
53 INT197610 Negative_regulation of Negative_regulation of Pgr 1 0.25 0.49 0
54 INT197604 Positive_regulation of Regulation of Pgr 1 0.29 0.49 0
55 INT197598 Negative_regulation of Localization of Pgr 1 0.21 0.28 0
56 INT236245 Negative_regulation of Localization of PGR 1 0.02 1.24 0
57 INT197597 Positive_regulation of Localization of Pgr 1 0.25 0.29 0
58 INT126986 Gene_expression of UBR5 1 0.26 0 0
59 INT68495 Negative_regulation of Binding of PGR 1 0.43 0 0
60 INT274710 Positive_regulation of Positive_regulation of PGR 1 0.08 1.21 0
61 INT272385 Negative_regulation of Positive_regulation of Pgr 1 0.04 0.21 0
62 INT325286 Positive_regulation of UBR5 1 0.02 2.37 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox