GO:0050852

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Name T cell receptor signaling pathway
Categary Process
Go Slim No
Go Link GO:0050852
Unique Molecular Interactions 1285
Total Molecular Interactions 1664
Total Single Events 13174
Pain Genes Associated 81

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for T cell receptor signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported for T cell receptor signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT61359 TNF Positive_regulation of NFKB1 11 0.63 6.66 3.89
2 INT223866 Ltp Positive_regulation of Positive_regulation of Mapk1 2 0.46 0.75 2.61
3 INT238914 Positive_regulation of CNR1 Positive_regulation of Phosphorylation of MAPK1 1 0.19 3.22 2.35
4 INT63918 Binding of Cck and Ripk2 1 0.28 0 2.07
5 INT281084 Prkaca Positive_regulation of Mapk1 2 0.25 0 2.06
6 INT81920 Binding of IL1B and NFKB1 1 0.04 1.54 1.85
7 INT81914 Binding of HSF1 and NFKB1 1 0.05 1.54 1.85
8 INT116092 TFF2 Positive_regulation of NFKB1 1 0.17 0.06 1.77
9 INT111076 Psen1 Regulation of Psenen 1 0.17 0.76 1.58
10 INT144280 ACP1 Negative_regulation of Phosphorylation of MAPK1 1 0.37 0.78 1.56
11 INT116093 OPRM1 Positive_regulation of Positive_regulation of NFKB1 1 0.36 0.08 1.56
12 INT241750 Binding of CD4 and ITIH4 14 0.18 5.72 1.53
13 INT174508 Binding of CD4 and HLA-B 1 0.14 4.68 1.53
14 INT112033 Gabrb3 Positive_regulation of Plcg1 1 0.05 0.18 1.49
15 INT169800 Negative_regulation of Adrbk1 Positive_regulation of Positive_regulation of Mapk1 1 0.39 1.04 1.45
16 INT261831 Mapk1 Negative_regulation of Hspg2 1 0.00 1.26 1.42
17 INT148450 Gene_expression of Inhbe Positive_regulation of Mapk1 1 0.07 1.35 1.41
18 INT161670 H2-M3 Positive_regulation of Positive_regulation of Mapk1 1 0.14 0.73 1.41
19 INT96262 Positive_regulation of Pik3cd Positive_regulation of Plcg1 1 0.03 0 1.39
20 INT106062 Positive_regulation of Oprl1 Positive_regulation of Mapk1 1 0.13 0.16 1.35
21 INT105295 WAS Regulation of PTGS1 1 0.02 0.13 1.27
22 INT121000 Binding of PAG1 and Nrm 1 0.13 0.67 1.25
23 INT172141 IL10 Negative_regulation of Gene_expression of HLA-DRA 2 0.14 0.89 1.23
24 INT166388 Binding of Gnb2l1 and Mapk1 1 0.49 0.49 1.21
25 INT96261 Positive_regulation of Pik3cd Positive_regulation of Plcg2 1 0.02 0 1.21
26 INT133046 TNF Positive_regulation of Positive_regulation of NFKB1 5 0.54 3.23 1.19
27 INT184402 Binding of HLA-DRB4 and HLA-E 1 0.00 3.1 1.19
28 INT55162 Binding of NFKB1 and RELA 10 0.30 2.82 1.18
29 INT121191 KCNMA1 Positive_regulation of Phosphorylation of MAPK1 1 0.06 0.61 1.18
30 INT169557 Cacna1h Positive_regulation of Mapk1 1 0.07 0.91 1.17
31 INT238916 CNR1 Positive_regulation of Phosphorylation of MAPK1 1 0.19 1.61 1.17
32 INT340439 Binding of HLA-DMA and SUGT1 1 0.00 4.1 1.16
33 INT161510 Tlr4 Positive_regulation of Mapk1 1 0.14 0.3 1.16
34 INT212815 WAS Positive_regulation of CNR1 1 0.01 0.62 1.16
35 INT212824 WAS Positive_regulation of Cnr1 1 0.21 0.62 1.16
36 INT147447 ADCYAP1 Regulation of Localization of RELA 1 0.50 1.12 1.15
37 INT147448 ADCYAP1 Regulation of Localization of NFKB1 1 0.47 1.12 1.15
38 INT346986 Binding of SHC3 and PAG1 1 0.35 1.02 1.12
39 INT107266 Binding of HLA-DRB1 and TNF 1 0.29 1.41 1.1
40 INT107265 Binding of HLA-DRB1 and ITGAL 1 0.01 1.41 1.1
41 INT107263 Binding of HLA-DRB1 and NCR3 1 0.40 1.42 1.1
42 INT101715 PLAT Positive_regulation of NFKB1 2 0.11 0.99 1.09
43 INT105113 Plat Positive_regulation of NFKB1 1 0.03 1.06 1.06
44 INT133072 GATA3 Positive_regulation of Transcription of OPRM1 1 0.35 0 1.04
45 INT156245 NFKB1 Positive_regulation of Regulation of TNF 1 0.45 0.76 1.03
46 INT101067 MAP3K15 Positive_regulation of MAPK1 1 0.21 0.47 1.03
47 INT316128 TCF21 Negative_regulation of Gene_expression of HLA-DRA 1 0.07 0.13 0.99
48 INT140652 IGF1 Positive_regulation of Phosphorylation of MAPK1 1 0.26 0.63 0.98
49 INT133071 STAT6 Positive_regulation of Gene_expression of GATA3 1 0.55 0 0.95
50 INT100018 TNF Positive_regulation of MAPK1 3 0.24 1.56 0.94
51 INT152388 Binding of NFKB1 and OPRM1 1 0.04 0.14 0.94
52 INT144281 ACP1 Negative_regulation of Positive_regulation of MAPK1 1 0.27 0.58 0.94
53 INT152389 Negative_regulation of Binding of NFKB1 and OPRM1 1 0.05 0.14 0.94
54 INT144285 ACP1 Negative_regulation of MAPK1 1 0.37 0.58 0.93
55 INT223871 Ltp Positive_regulation of Gene_expression of Mapk1 1 0.33 0 0.93
56 INT96260 Pik3cd Regulation of Plcg2 1 0.02 0 0.92
57 INT34271 Positive_regulation of WAS Positive_regulation of Oprd1 1 0.01 0 0.91
58 INT34273 WAS Regulation of Oprd1 1 0.00 0 0.91
59 INT302828 Mapkapk5 Positive_regulation of Mapk1 1 0.07 1.38 0.91
60 INT34272 WAS Positive_regulation of Oprd1 1 0.01 0 0.91
61 INT343918 IgG Positive_regulation of Phosphorylation of MAPK1 1 0.01 3.57 0.91
62 INT90387 ROS1 Positive_regulation of NFKB1 4 0.32 2.35 0.87
63 INT188196 LIF Regulation of MAPK1 1 0.21 2.26 0.87
64 INT188214 OSM Regulation of MAPK1 1 0.20 2.27 0.87
65 INT226340 Binding of CD4 and IFNA1 3 0.03 3.84 0.85
66 INT190183 MAPK1 Regulation of CDCP1 1 0.00 1.19 0.85
67 INT340437 Binding of SERPINH1 and HLA-DRB4 1 0.00 2.26 0.84
68 INT174509 Binding of CD4 and CD28 1 0.26 1.68 0.84
69 INT161305 NFKB1 Positive_regulation of IL2 1 0.25 0.25 0.83
70 INT106312 NFKB1 Regulation of S100A4 1 0.14 1.1 0.83
71 INT320120 MTX1 Positive_regulation of PTEN 1 0.04 0.09 0.82
72 INT66206 Negative_regulation of TNF Positive_regulation of NFKB1 2 0.53 1.71 0.81
73 INT262572 Ngf Positive_regulation of Mapk1 2 0.04 0.52 0.81
74 INT140966 NFKB1 Positive_regulation of Positive_regulation of CPOX 1 0.08 0.66 0.8
75 INT104831 Binding of GLI2 and NFKB1 1 0.08 0 0.8
76 INT237204 Binding of LGALS4 and Cd3e 1 0.15 2.61 0.8
77 INT161520 H2-M3 Regulation of Positive_regulation of Mapk1 1 0.09 0.47 0.79
78 INT132977 Tac1 Positive_regulation of Mapk1 1 0.06 0.17 0.79
79 INT117909 Mastl Positive_regulation of Mapk1 1 0.04 0 0.79
80 INT132894 CHUK Regulation of Gene_expression of Nos2 1 0.00 0.21 0.79
81 INT163830 ERBB2 Positive_regulation of MAPK1 1 0.06 1.63 0.76
82 INT128404 Mapk1 Positive_regulation of Phosphorylation of Gja1 1 0.65 0.73 0.73
83 INT121843 HLA-DRB5 Negative_regulation of Accn4 1 0.00 0.54 0.73
84 INT205120 Binding of CD4 and CD8A 3 0.15 2.83 0.72
85 INT146463 TNFSF10 Positive_regulation of NFKB1 2 0.08 2.45 0.71
86 INT146461 IFNG Positive_regulation of NFKB1 1 0.01 1.44 0.71
87 INT153123 NFKBIA Negative_regulation of Phosphorylation of RELA 1 0.03 2.01 0.71
88 INT103134 DCSTAMP Positive_regulation of NFKB1 2 0.07 1.43 0.7
89 INT166386 Mapk1 Regulation of Gene_expression of Gnb2l1 1 0.46 0.25 0.7
90 INT320633 Positive_regulation of MAPK1 Regulation of BCL2 1 0.04 1.21 0.7
91 INT194685 MAPK1 Regulation of Gene_expression of IL10 1 0.06 1.18 0.7
92 INT320634 Positive_regulation of MAPK1 Regulation of PBX2 1 0.03 1.21 0.7
93 INT223868 Mapk1 Positive_regulation of Creb1 2 0.17 0.34 0.68
94 INT223876 Mapk1 Positive_regulation of Atf6b 1 0.10 0 0.68
95 INT211916 Fig4 Positive_regulation of Mapk1 1 0.13 0.25 0.66
96 INT191332 AMPH Positive_regulation of Mapk1 1 0.76 0 0.66
97 INT270763 IL1B Negative_regulation of IKBKB 1 0.04 1.13 0.66
98 INT124477 MAP2K1 Positive_regulation of Positive_regulation of MAPK1 1 0.12 1.35 0.65
99 INT266064 Binding of PAG1 and Creb1 1 0.04 1.52 0.65
100 INT111936 Binding of PIK3CA and PTK2 1 0.19 0.67 0.65
101 INT148173 Positive_regulation of Grm5 Positive_regulation of Phosphorylation of Mapk1 1 0.01 0.45 0.65
102 INT160119 EPO Regulation of Gene_expression of NFKB1 1 0.02 0.2 0.64
103 INT169285 PTPLA Positive_regulation of GRAP2 1 0.03 0.15 0.63
104 INT169101 Binding of HLA-A and HLA-DRB1 1 0.24 1.09 0.63
105 INT266065 Positive_regulation of Binding of Ceacam3 and PAG1 1 0.03 1.44 0.63
106 INT174500 Positive_regulation of Binding of CD4 and HLA-B 1 0.21 2.33 0.63
107 INT266062 Binding of Ceacam3 and PAG1 1 0.02 1.44 0.63
108 INT281092 Adcy1 Positive_regulation of Mapk1 1 0.21 0 0.63
109 INT192332 UBR7 Negative_regulation of TXK 1 0.00 1.38 0.63
110 INT121713 WAS Positive_regulation of Gene_expression of SELP 1 0.30 0.49 0.63
111 INT120851 NFKB1 Positive_regulation of Localization of TNF 3 0.04 2.05 0.62
112 INT281090 Prkacb Positive_regulation of Mapk1 1 0.06 0 0.62
113 INT66207 Positive_regulation of TNF Positive_regulation of NFKB1 1 0.42 0.08 0.61
114 INT144248 CGA Regulation of Positive_regulation of NFKB1 1 0.15 1.66 0.61
115 INT144256 CGA Regulation of Gene_expression of NFKB1 1 0.21 1.66 0.61
116 INT73073 Binding of Cd3e and Oprk1 1 0.28 0.06 0.59
117 INT197050 Binding of HLA-DOA and HLA-E 2 0.08 1.73 0.58
118 INT291262 Positive_regulation of INS Positive_regulation of Mapk1 1 0.03 1.78 0.58
119 INT291258 INS Positive_regulation of Mapk1 1 0.04 1.77 0.58
120 INT169290 CNR1 Positive_regulation of Negative_regulation of TXK 1 0.10 0.18 0.58
121 INT115146 MAPK1 Positive_regulation of EGR1 3 0.13 2.43 0.57
122 INT148172 Mapk1 Positive_regulation of Phosphorylation of Kcnd2 1 0.49 0.55 0.57
123 INT147071 NFKB1 Regulation of Gene_expression of PTGES 1 0.36 0.35 0.57
124 INT190181 Positive_regulation of PIK3CA Positive_regulation of MMP12 1 0.01 0.54 0.56
125 INT182348 Binding of Cd3e and Crp 1 0.15 2.33 0.56
126 INT113548 NFKB1 Regulation of Localization of PLAU 1 0.26 1.93 0.55
127 INT201949 CXCL10 Positive_regulation of Phosphorylation of MAPK1 1 0.15 0.79 0.55
128 INT121994 EGF Positive_regulation of Positive_regulation of MAPK1 1 0.25 0 0.55
129 INT156246 NFKB1 Regulation of Gene_expression of TNF 1 0.17 0.35 0.54
130 INT105111 Negative_regulation of Plat Positive_regulation of NFKB1 1 0.03 0.53 0.54
131 INT323146 PRKCA Positive_regulation of MAPK1 1 0.02 0 0.54
132 INT85125 IL3 Positive_regulation of MAPK1 1 0.30 0.81 0.53
133 INT105110 Cxcl12 Positive_regulation of NFKB1 1 0.06 0.54 0.53
134 INT85121 CSF2 Positive_regulation of MAPK1 1 0.07 0.8 0.53
135 INT85115 IL5 Positive_regulation of MAPK1 1 0.14 0.81 0.53
136 INT105108 Negative_regulation of Cxcl12 Positive_regulation of NFKB1 1 0.05 0.54 0.53
137 INT171909 MAPK8 Positive_regulation of Gene_expression of MAPK1 1 0.08 1.55 0.52
138 INT171910 MAPK1 Positive_regulation of MAPK9 1 0.10 1.55 0.52
139 INT201939 CXCL10 Positive_regulation of MAPK1 1 0.11 0.72 0.52
140 INT171906 MAPK1 Positive_regulation of Gene_expression of MAPK14 1 0.08 1.55 0.52
141 INT171914 MAPK8IP3 Positive_regulation of Gene_expression of MAPK1 1 0.06 1.55 0.52
142 INT122872 SEMA6A Positive_regulation of MAPK1 1 0.56 0 0.52
143 INT131368 MAPK1 Positive_regulation of Bcar3 1 0.00 0.37 0.51
144 INT62299 Binding of CD4 and SGCG 1 0.39 1.23 0.51
145 INT36084 Binding of HLA-DRB4 and Igkv16-104 1 0.04 1.01 0.51
146 INT131369 MAPK1 Positive_regulation of Il4 1 0.01 0.37 0.51
147 INT356286 Ngf Regulation of Positive_regulation of Mapk1 1 0.03 0.76 0.5
148 INT139834 NFKB1 Regulation of Gene_expression of SELE 1 0.18 0.49 0.5
149 INT356279 Gdnf Regulation of Positive_regulation of Mapk1 1 0.03 0.76 0.5
150 INT139835 NFKB1 Regulation of SELE 1 0.41 0.49 0.5
151 INT194676 Negative_regulation of MAPK1 Negative_regulation of Gene_expression of IL10 1 0.05 0.34 0.5
152 INT244028 Positive_regulation of Binding of Cacnb3 and Tfap2a 1 0.01 0.24 0.49
153 INT320121 Binding of PTEN and TNF 1 0.05 0.76 0.49
154 INT244021 Positive_regulation of Binding of Cacnb3 and Prkaca 1 0.02 0.24 0.49
155 INT244036 Binding of Cacnb3 and Prkaca 1 0.01 0.24 0.49
156 INT106072 NFKB1 Positive_regulation of Gene_expression of A2M 1 0.19 0.75 0.49
157 INT244060 Binding of Cacnb3 and Tfap2a 1 0.00 0.24 0.49
158 INT135588 Positive_regulation of IKBKE Positive_regulation of NFKB1 1 0.18 1.29 0.48
159 INT135587 IKBKE Positive_regulation of NFKB1 1 0.18 1.28 0.48
160 INT102553 HGF Positive_regulation of Phosphorylation of MAPK1 1 0.40 0.49 0.48
161 INT191948 NFKB1 Regulation of Gene_expression of NOS2 1 0.38 1 0.47
162 INT251297 Binding of C2 and CD4 1 0.04 0.35 0.47
163 INT185917 Binding of AR and MAPK1 1 0.07 0.5 0.47
164 INT106073 IL1B Positive_regulation of Positive_regulation of NFKB1 1 0.41 0.7 0.47
165 INT102555 HGF Positive_regulation of MAPK1 1 0.38 0.47 0.47
166 INT265646 Binding of Mapk1 and Mapk14 1 0.01 1.53 0.46
167 INT109780 WAS Regulation of Localization of Acot1 1 0.01 0.26 0.46
168 INT254198 Mapk1 Positive_regulation of Mapk8 1 0.01 0.87 0.46
169 INT254216 Mapk14 Positive_regulation of Mapk1 1 0.02 0.87 0.46
170 INT254222 Mapk1 Positive_regulation of Mapk14 1 0.02 0.86 0.46
171 INT108332 EGF Positive_regulation of Phosphorylation of MAPK1 5 0.48 1.85 0.45
172 INT144245 CGA Negative_regulation of Positive_regulation of NFKB1 1 0.13 0.79 0.45
173 INT45035 Binding of HLA-B and HLA-DRB4 2 0.16 0.74 0.44
174 INT190870 BDNF Positive_regulation of Phosphorylation of Mapk1 1 0.12 0.54 0.44
175 INT343846 MAPK1 Positive_regulation of FOS 1 0.04 1.29 0.44
176 INT223863 Positive_regulation of Mapk1 Positive_regulation of Positive_regulation of Ltp 1 0.31 0 0.43
177 INT264473 Il1a Positive_regulation of Mapk1 1 0.00 0 0.43
178 INT157343 Binding of AQP4 and HLA-DPB1 1 0.30 0.89 0.43
179 INT337326 PIK3CD Positive_regulation of Localization of ITPR3 1 0.02 0 0.43
180 INT188211 IL6 Regulation of MAPK1 1 0.16 1.13 0.43
181 INT337325 PIK3CD Positive_regulation of Phosphorylation of IL2RG 1 0.00 0 0.43
182 INT340438 Binding of HLA-DMA and MRAP 1 0.02 1.69 0.43
183 INT265647 Binding of Ephb1 and Mapk1 1 0.00 1.48 0.43
184 INT337324 PIK3CD Positive_regulation of Gene_expression of ITPR3 1 0.02 0 0.43
185 INT264471 Il1a Positive_regulation of Gene_expression of Mapk1 1 0.01 0 0.43
186 INT103128 Positive_regulation of DCSTAMP Positive_regulation of NFKB1 1 0.07 0.73 0.43
187 INT292634 IL4 Positive_regulation of Gene_expression of FOXP3 1 0.10 0.42 0.43
188 INT174501 Binding of HLA-B and HLA-DOA 2 0.03 1.84 0.42
189 INT160046 INPPL1 Regulation of Gene_expression of PTEN 1 0.41 0.6 0.42
190 INT316121 IL10 Regulation of Gene_expression of HLA-DRA 1 0.09 0.46 0.42
191 INT160047 PTEN Regulation of Gene_expression of AKT1 1 0.33 0.6 0.42
192 INT238913 MAPK3 Regulation of Positive_regulation of MAPK1 1 0.11 0.39 0.42
193 INT161521 Negative_regulation of H2-M3 Positive_regulation of Mapk1 1 0.14 0.41 0.42
194 INT160049 PTEN Regulation of Gene_expression of INPPL1 1 0.41 0.6 0.42
195 INT194722 Negative_regulation of MAPK1 Negative_regulation of Gene_expression of CRP 1 0.09 1.49 0.41
196 INT274864 Negative_regulation of Mapk1 Negative_regulation of Gene_expression of TNF 1 0.05 1.15 0.41
197 INT107704 IL1B Positive_regulation of Localization of RELA 1 0.02 0.13 0.41
198 INT161522 H2-M3 Positive_regulation of Mapk1 1 0.15 0.41 0.41
199 INT274867 Negative_regulation of Mapk1 Negative_regulation of TNF 1 0.03 1.15 0.41
200 INT261652 Binding of MAPK1 and PSEN1 1 0.22 1.25 0.41

Single Events

The table below shows the top 100 pain related interactions that have been reported for T cell receptor signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported in T cell receptor signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT95787 Positive_regulation of Mapk1 568 0.70 226.51 220.94
2 INT81417 Gene_expression of PAG1 94 0.58 90.85 92.79
3 INT71789 Positive_regulation of MAPK1 396 0.70 234.44 89.27
4 INT54571 Positive_regulation of NFKB1 263 0.70 138.99 87.32
5 INT92434 Phosphorylation of Mapk1 287 0.82 91.65 83.46
6 INT19771 Positive_regulation of PAG1 69 0.61 75.61 76.88
7 INT48934 Positive_regulation of Mapk1 157 0.70 60.61 61.72
8 INT71786 Phosphorylation of MAPK1 256 0.82 110.09 46.17
9 INT16364 Gene_expression of HLA-DRA 234 0.78 118.81 45.01
10 INT13556 Gene_expression of CD4 367 0.78 230.82 41.74
11 INT92437 Positive_regulation of Phosphorylation of Mapk1 113 0.70 32.19 40.29
12 INT114751 Gene_expression of Mapk1 137 0.76 60.14 39.98
13 INT102611 Negative_regulation of Positive_regulation of Mapk1 74 0.58 35.57 39.37
14 INT109434 Phosphorylation of Mapk1 110 0.82 61.64 34.05
15 INT48925 Gene_expression of Mapk1 95 0.74 42.21 32.91
16 INT117112 Negative_regulation of Mapk1 87 0.56 40.34 31.18
17 INT56072 Negative_regulation of NFKB1 94 0.59 53.16 28.19
18 INT83708 Negative_regulation of MAPK1 156 0.57 84.93 27.85
19 INT95788 Positive_regulation of Positive_regulation of Mapk1 83 0.69 24.75 25.84
20 INT12124 Gene_expression of MAPK1 141 0.75 82.4 25.58
21 INT254567 Positive_regulation of Gene_expression of PAG1 10 0.39 31.15 24.26
22 INT55170 Gene_expression of NFKB1 97 0.77 52.75 23.04
23 INT66208 Positive_regulation of Positive_regulation of NFKB1 45 0.68 20.17 22.62
24 INT5328 Positive_regulation of CD4 191 0.69 133.43 21.31
25 INT11161 Gene_expression of HLA-DRB1 121 0.78 75.33 20.96
26 INT91462 Positive_regulation of Phosphorylation of MAPK1 99 0.67 40.28 18.99
27 INT99058 Regulation of PAG1 18 0.45 21.62 18.5
28 INT95790 Regulation of Mapk1 55 0.61 21.17 16.31
29 INT25517 Regulation of NFKB1 41 0.61 22.28 16.09
30 INT111073 Gene_expression of Psen1 167 0.76 78.65 15.83
31 INT111462 Negative_regulation of Phosphorylation of Mapk1 45 0.57 19.49 15.59
32 INT54572 Negative_regulation of Positive_regulation of NFKB1 46 0.58 21.45 15.47
33 INT75531 Regulation of MAPK1 70 0.61 34.39 15.42
34 INT128401 Positive_regulation of Positive_regulation of Mapk1 39 0.70 10.88 15.38
35 INT10709 Negative_regulation of CD4 106 0.59 95.6 14.89
36 INT63553 Binding of PAG1 14 0.48 12.51 14.76
37 INT16321 Gene_expression of Cd3e 111 0.72 49.9 14.21
38 INT80688 Positive_regulation of Positive_regulation of MAPK1 72 0.69 39.35 14.11
39 INT39733 Localization of NFKB1 59 0.79 22.76 13.99
40 INT56651 Binding of HLA-DRB1 58 0.48 52.25 13.68
41 INT55168 Binding of NFKB1 55 0.48 22.94 13.15
42 INT150676 Positive_regulation of Gene_expression of Mapk1 30 0.45 10.06 12.37
43 INT119396 Regulation of Positive_regulation of Mapk1 22 0.61 7.88 12.25
44 INT118905 Positive_regulation of Positive_regulation of PAG1 8 0.40 7.55 12.25
45 INT36287 Binding of CD4 96 0.47 58.93 11.88
46 INT87698 Gene_expression of WAS 25 0.58 8.75 11.83
47 INT69029 Gene_expression of PTPRC 127 0.75 74.26 11.57
48 INT75525 Negative_regulation of Positive_regulation of MAPK1 40 0.59 25.15 11.15
49 INT96259 Positive_regulation of Plcg1 11 0.49 3.01 11.15
50 INT23402 Binding of HLA-DOA 74 0.48 52.01 10.89
51 INT23177 Negative_regulation of Gene_expression of HLA-DRA 50 0.44 16.99 10.55
52 INT48921 Regulation of Mapk1 25 0.49 19.51 10.41
53 INT16404 Regulation of CD4 54 0.61 33.05 10.29
54 INT254566 Negative_regulation of Gene_expression of PAG1 7 0.33 9.51 9.91
55 INT70134 Negative_regulation of TXK 124 0.23 81.96 9.59
56 INT94196 Negative_regulation of Phosphorylation of MAPK1 60 0.59 31.64 9.16
57 INT155944 Gene_expression of Foxp3 66 0.66 24.37 9.12
58 INT109432 Negative_regulation of Phosphorylation of Mapk1 19 0.54 7.01 8.98
59 INT66213 Localization of RELA 63 0.78 14.71 8.77
60 INT34268 Binding of WAS 14 0.47 4.41 8.67
61 INT119831 Gene_expression of PTEN 55 0.75 40.37 8.57
62 INT91772 Gene_expression of PSEN1 115 0.75 38.12 8.48
63 INT169015 Gene_expression of FOXP3 50 0.60 33.18 8.4
64 INT126848 Positive_regulation of Phosphorylation of Mapk1 30 0.50 15.94 8.34
65 INT87699 Positive_regulation of WAS 16 0.45 5.84 8.03
66 INT81419 Localization of PAG1 10 0.64 11.1 8.01
67 INT110004 Gene_expression of Plcg1 7 0.41 2.61 7.87
68 INT38503 Positive_regulation of Ripk2 11 0.67 2.9 7.47
69 INT120401 Positive_regulation of PIK3CD 33 0.45 14.89 7.37
70 INT5381 Gene_expression of FYN 18 0.75 7.65 7.35
71 INT6596 Positive_regulation of HLA-DRB1 33 0.61 27.01 7.26
72 INT33105 Regulation of WAS 11 0.60 3.61 7.18
73 INT66210 Regulation of Positive_regulation of NFKB1 16 0.60 9.46 7.08
74 INT76120 Gene_expression of Ptprc 102 0.59 30.42 7.02
75 INT12771 Positive_regulation of IKBKG 27 0.69 5.99 7.02
76 INT17049 Localization of CD4 57 0.75 35.33 6.89
77 INT13520 Binding of HLA-DRB4 30 0.42 32.65 6.74
78 INT23246 Gene_expression of HLA-DRB4 37 0.64 36.79 6.61
79 INT48928 Positive_regulation of Gene_expression of Mapk1 19 0.48 9.38 6.59
80 INT92716 Negative_regulation of PAG1 6 0.51 5.82 6.32
81 INT57256 Gene_expression of HLA-DQA2 52 0.55 23.87 6.27
82 INT38595 Localization of BCAR1 8 0.73 2.9 6.25
83 INT139964 Regulation of Phosphorylation of Mapk1 12 0.58 10.04 6.1
84 INT17551 Positive_regulation of Gene_expression of HLA-DRA 31 0.70 15.39 6
85 INT18967 Positive_regulation of Gene_expression of HLA-DRB1 14 0.49 13.56 5.99
86 INT122653 Positive_regulation of Gene_expression of CD4 48 0.68 22.5 5.96
87 INT52907 Regulation of Gene_expression of HLA-DRA 28 0.34 5.94 5.96
88 INT130111 Regulation of Positive_regulation of MAPK1 14 0.36 11.01 5.9
89 INT111069 Regulation of Psen1 19 0.44 7.78 5.87
90 INT60724 Gene_expression of Psen2 30 0.72 27 5.79
91 INT47976 Protein_catabolism of NFKBIA 17 0.88 7.57 5.79
92 INT254570 Regulation of Gene_expression of PAG1 3 0.35 6.72 5.76
93 INT23401 Gene_expression of HLA-DOA 91 0.30 38.21 5.52
94 INT71779 Positive_regulation of Gene_expression of MAPK1 27 0.47 21.41 5.39
95 INT78728 Negative_regulation of Binding of NFKB1 18 0.58 6.89 5.39
96 INT66209 Negative_regulation of Localization of NFKB1 23 0.58 8.2 5.31
97 INT18681 Gene_expression of Thy1 80 0.71 38.8 5.23
98 INT120073 Positive_regulation of Itk 34 0.44 23.45 5.09
99 INT66211 Positive_regulation of Localization of NFKB1 20 0.68 8.18 5.01
100 INT37976 Binding of Ripk2 6 0.47 0.27 5.01
101 INT20459 Regulation of Ripk2 5 0.44 0 4.53
102 INT55171 Gene_expression of RELA 80 0.75 17.17 4.47
103 INT116011 Positive_regulation of Gata3 5 0.31 3.17 4.21
104 INT110343 Negative_regulation of PIK3CD 22 0.40 5.84 4.2
105 INT111067 Positive_regulation of Gene_expression of Psen1 32 0.68 21.2 4.19
106 INT158416 Localization of Mapk1 19 0.67 5.32 4.18
107 INT202417 Gene_expression of Gata3 16 0.61 7.84 4.12
108 INT12772 Positive_regulation of Positive_regulation of IKBKG 9 0.69 0.84 4.12
109 INT133244 Regulation of Positive_regulation of Mapk1 11 0.43 3.52 4.03
110 INT3405 Gene_expression of BCAR1 14 0.71 8.89 4.02
111 INT48456 Localization of WAS 6 0.56 1.63 3.95
112 INT56077 Protein_catabolism of NFKB1 16 0.98 8.03 3.94
113 INT15133 Regulation of HLA-DRA 19 0.34 5.84 3.9
114 INT113924 Binding of Mapk1 27 0.38 8.64 3.84
115 INT56075 Transcription of NFKB1 13 0.71 9.03 3.83
116 INT229912 Phosphorylation of Fyn 5 0.42 2.57 3.78
117 INT123908 Positive_regulation of HLA-DQB1 12 0.21 10.5 3.71
118 INT79231 Positive_regulation of Gene_expression of NFKB1 18 0.67 9.16 3.66
119 INT134149 Negative_regulation of Gene_expression of NFKB1 7 0.55 4.25 3.63
120 INT170528 Negative_regulation of Gene_expression of CD4 25 0.41 17.98 3.6
121 INT79477 Binding of HLA-DMA 19 0.26 13.78 3.47
122 INT78284 Positive_regulation of PTPRC 40 0.49 27.17 3.45
123 INT73557 Positive_regulation of RELA 57 0.46 8.7 3.43
124 INT25386 Positive_regulation of Cd3e 30 0.62 13.91 3.41
125 INT260159 Negative_regulation of Positive_regulation of PAG1 2 0.33 1.86 3.39
126 INT211591 Negative_regulation of PSEN1 14 0.57 5.73 3.26
127 INT28249 Positive_regulation of HLA-DRA 25 0.70 13.63 3.25
128 INT3403 Positive_regulation of BCAR1 18 0.63 18.95 3.23
129 INT36286 Binding of Cd3e 33 0.36 10.11 3.21
130 INT171368 Regulation of Phosphorylation of Mapk1 14 0.61 4.77 3.14
131 INT139801 Phosphorylation of NFKB1 9 0.66 5.2 3.13
132 INT66212 Negative_regulation of Localization of RELA 13 0.57 2.48 3.09
133 INT38594 Positive_regulation of Localization of BCAR1 3 0.63 0.44 3.07
134 INT105297 Negative_regulation of Regulation of WAS 3 0.28 0.98 3.07
135 INT192676 Binding of PTEN 14 0.46 10.58 3.06
136 INT271442 Positive_regulation of Thy1 10 0.40 6.64 3.05
137 INT91761 Gene_expression of PSEN2 38 0.75 22.93 3.03
138 INT12770 Negative_regulation of Positive_regulation of IKBKG 7 0.56 0.34 3.02
139 INT193936 Positive_regulation of PSEN1 5 0.58 11.57 2.95
140 INT133080 Gene_expression of GATA3 15 0.61 5.64 2.89
141 INT200895 Localization of Mapk1 6 0.67 2.08 2.82
142 INT6025 Negative_regulation of RIPK2 4 0.57 0.96 2.82
143 INT271447 Positive_regulation of Positive_regulation of HLA-DQB1 1 0.06 5.87 2.8
144 INT86341 Positive_regulation of Cacnb3 3 0.44 0.91 2.79
145 INT89397 Positive_regulation of PIK3CA 33 0.67 16.98 2.78
146 INT169112 Negative_regulation of Positive_regulation of Mapk1 9 0.59 1.84 2.78
147 INT145821 Negative_regulation of Gene_expression of Mapk1 16 0.41 8.05 2.77
148 INT79476 Gene_expression of HLA-DMA 23 0.38 9.5 2.76
149 INT161310 Negative_regulation of LCK 17 0.42 8.75 2.74
150 INT152927 Negative_regulation of Mapk1 16 0.41 5.85 2.73
151 INT19421 Positive_regulation of RIPK2 6 0.49 5.63 2.72
152 INT53443 Gene_expression of IKBKG 15 0.65 7.5 2.71
153 INT107968 Positive_regulation of NFKBIA 9 0.46 5.27 2.69
154 INT47974 Negative_regulation of Protein_catabolism of NFKBIA 7 0.49 2.38 2.69
155 INT61004 Negative_regulation of Regulation of Ripk2 1 0.41 0 2.68
156 INT209889 Gene_expression of TRAF6 13 0.63 6.85 2.67
157 INT87340 Negative_regulation of BCAR1 8 0.38 6.96 2.63
158 INT202419 Positive_regulation of Gene_expression of Gata3 6 0.52 5.47 2.6
159 INT188344 Positive_regulation of Gene_expression of Foxp3 10 0.36 5.97 2.56
160 INT89281 Negative_regulation of Gene_expression of HLA-DRB1 10 0.30 5.9 2.55
161 INT187454 Binding of Ptprc 34 0.38 9.66 2.54
162 INT18969 Gene_expression of HLA-DQA1 29 0.65 12.19 2.54
163 INT54720 Positive_regulation of HLA-DRB5 9 0.34 6.7 2.51
164 INT122003 Phosphorylation of NFKBIA 9 0.59 5.44 2.51
165 INT119838 Positive_regulation of PTEN 25 0.67 21.71 2.5
166 INT230758 Positive_regulation of Gene_expression of PTPRC 11 0.49 6.04 2.45
167 INT71305 Regulation of Gene_expression of NFKB1 9 0.61 5.41 2.44
168 INT130476 Phosphorylation of Fyn 8 0.80 2.99 2.44
169 INT12769 Localization of IKBKG 6 0.15 1.66 2.43
170 INT163544 Binding of Psen1 40 0.36 15.28 2.42
171 INT186116 Regulation of Gene_expression of MAPK1 9 0.44 5.85 2.32
172 INT172078 Localization of Cd3e 22 0.37 9.88 2.27
173 INT132893 Binding of CHUK 1 0.00 0.63 2.25
174 INT14854 Regulation of Gene_expression of HLA-DRB1 10 0.39 5.27 2.19
175 INT179885 Regulation of PTEN 8 0.26 11.88 2.18
176 INT170469 Gene_expression of THY1 66 0.65 11.9 2.15
177 INT122671 Positive_regulation of LCK 4 0.13 2.69 2.14
178 INT264967 Positive_regulation of Positive_regulation of PIK3CD 4 0.18 1.97 2.13
179 INT170482 Regulation of Gene_expression of Mapk1 5 0.43 5.73 2.1
180 INT255708 Transcription of PAG1 2 0.53 0.84 2.08
181 INT181507 Positive_regulation of Psen1 22 0.49 7.59 2.04
182 INT37977 Negative_regulation of Ripk2 3 0.42 0.92 2.03
183 INT129318 Negative_regulation of NFKBIA 10 0.38 6.19 2.02
184 INT60723 Localization of Psen2 5 0.68 2.11 2.02
185 INT109906 Localization of MAPK1 12 0.54 1.68 2.01
186 INT83709 Negative_regulation of Gene_expression of MAPK1 12 0.41 6.57 2.01
187 INT132892 Positive_regulation of CHUK 3 0.08 1.62 2.01
188 INT123530 Phosphorylation of RELA 9 0.80 3.46 1.99
189 INT221431 Negative_regulation of FOXP3 8 0.40 9.92 1.98
190 INT57339 Negative_regulation of HLA-DRA 17 0.49 7.67 1.96
191 INT26317 Gene_expression of NFKBIA 5 0.45 2.97 1.96
192 INT110003 Phosphorylation of Plcg1 2 0.37 0.91 1.96
193 INT204139 Positive_regulation of Gene_expression of BCAR1 1 0.23 0.9 1.96
194 INT118291 Binding of TXK 19 0.10 11.77 1.94
195 INT193939 Binding of PSEN1 10 0.36 6.16 1.93
196 INT56080 Transcription of NFKBIA 2 0.40 2.16 1.93
197 INT155015 Positive_regulation of HLA-DOA 6 0.23 4.45 1.92
198 INT49380 Localization of FYN 4 0.78 0.9 1.87
199 INT56078 Negative_regulation of Protein_catabolism of NFKB1 7 0.42 4.44 1.83
200 INT8787 Negative_regulation of WAS 4 0.42 2.42 1.81
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