GO:0050853

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Name B cell receptor signaling pathway
Categary Process
Go Slim No
Go Link GO:0050853
Unique Molecular Interactions 912
Total Molecular Interactions 1216
Total Single Events 10815
Pain Genes Associated 42

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for B cell receptor signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported for B cell receptor signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT149117 Binding of CD80 and CTLA4 31 0.52 12.7 7.73
2 INT155484 Binding of CD86 and CTLA4 15 0.52 8.85 6.09
3 INT186126 Binding of CD28 and CTLA4 9 0.52 4.13 3.12
4 INT223866 Ltp Positive_regulation of Positive_regulation of Mapk1 2 0.46 0.75 2.61
5 INT238914 Positive_regulation of CNR1 Positive_regulation of Phosphorylation of MAPK1 1 0.19 3.22 2.35
6 INT281084 Prkaca Positive_regulation of Mapk1 2 0.25 0 2.06
7 INT165200 Binding of CTLA4 and Crp 1 0.09 1.64 1.91
8 INT122428 Binding of Ighm and Prkci 1 0.00 0 1.66
9 INT144280 ACP1 Negative_regulation of Phosphorylation of MAPK1 1 0.37 0.78 1.56
10 INT156008 Bcl2 Regulation of Localization of Aifm1 1 0.17 1.92 1.47
11 INT169800 Negative_regulation of Adrbk1 Positive_regulation of Positive_regulation of Mapk1 1 0.39 1.04 1.45
12 INT261831 Mapk1 Negative_regulation of Hspg2 1 0.00 1.26 1.42
13 INT148450 Gene_expression of Inhbe Positive_regulation of Mapk1 1 0.07 1.35 1.41
14 INT161670 H2-M3 Positive_regulation of Positive_regulation of Mapk1 1 0.14 0.73 1.41
15 INT122430 Negative_regulation of Binding of Ighm and Prkci 1 0.00 0 1.36
16 INT168865 Cd38 Regulation of Wdtc1 1 0.03 0.12 1.35
17 INT106062 Positive_regulation of Oprl1 Positive_regulation of Mapk1 1 0.13 0.16 1.35
18 INT145930 ecs Positive_regulation of Gene_expression of Bcl2 1 0.01 2.06 1.34
19 INT265213 Binding of Ctla4 and Cd86 2 0.13 1.93 1.31
20 INT168866 Binding of RYR1 and Cd38 1 0.02 0.17 1.28
21 INT166388 Binding of Gnb2l1 and Mapk1 1 0.49 0.49 1.21
22 INT96261 Positive_regulation of Pik3cd Positive_regulation of Plcg2 1 0.02 0 1.21
23 INT121191 KCNMA1 Positive_regulation of Phosphorylation of MAPK1 1 0.06 0.61 1.18
24 INT169557 Cacna1h Positive_regulation of Mapk1 1 0.07 0.91 1.17
25 INT238916 CNR1 Positive_regulation of Phosphorylation of MAPK1 1 0.19 1.61 1.17
26 INT161510 Tlr4 Positive_regulation of Mapk1 1 0.14 0.3 1.16
27 INT101067 MAP3K15 Positive_regulation of MAPK1 1 0.21 0.47 1.03
28 INT122429 Prkci Regulation of Gene_expression of Ighm 1 0.00 0 1.02
29 INT122431 Prkci Negative_regulation of Negative_regulation of Ighm 1 0.00 0 1.02
30 INT122433 Prkci Negative_regulation of Ighm 1 0.00 0 1.02
31 INT142202 FL Positive_regulation of Bcl2 1 0.05 0.39 0.99
32 INT140652 IGF1 Positive_regulation of Phosphorylation of MAPK1 1 0.26 0.63 0.98
33 INT100018 TNF Positive_regulation of MAPK1 3 0.24 1.56 0.94
34 INT144281 ACP1 Negative_regulation of Positive_regulation of MAPK1 1 0.27 0.58 0.94
35 INT265210 Binding of Ctla4 and Cd28 2 0.16 1.45 0.93
36 INT144285 ACP1 Negative_regulation of MAPK1 1 0.37 0.58 0.93
37 INT223871 Ltp Positive_regulation of Gene_expression of Mapk1 1 0.33 0 0.93
38 INT96260 Pik3cd Regulation of Plcg2 1 0.02 0 0.92
39 INT149386 Binding of Lyn and TRPV4 1 0.40 1.14 0.91
40 INT302828 Mapkapk5 Positive_regulation of Mapk1 1 0.07 1.38 0.91
41 INT112765 Binding of Nfkb1 and Bcl2 1 0.00 1.37 0.91
42 INT343918 IgG Positive_regulation of Phosphorylation of MAPK1 1 0.01 3.57 0.91
43 INT188196 LIF Regulation of MAPK1 1 0.21 2.26 0.87
44 INT188214 OSM Regulation of MAPK1 1 0.20 2.27 0.87
45 INT166634 Binding of Bcl2 and Becn1 1 0.20 0.5 0.86
46 INT150864 RYBP Positive_regulation of Positive_regulation of Bcl2 1 0.01 0.66 0.86
47 INT190183 MAPK1 Regulation of CDCP1 1 0.00 1.19 0.85
48 INT262572 Ngf Positive_regulation of Mapk1 2 0.04 0.52 0.81
49 INT161520 H2-M3 Regulation of Positive_regulation of Mapk1 1 0.09 0.47 0.79
50 INT132977 Tac1 Positive_regulation of Mapk1 1 0.06 0.17 0.79
51 INT117909 Mastl Positive_regulation of Mapk1 1 0.04 0 0.79
52 INT163830 ERBB2 Positive_regulation of MAPK1 1 0.06 1.63 0.76
53 INT218935 Cyp3a23/3a1 Regulation of Bcl2 1 0.00 1.08 0.74
54 INT128404 Mapk1 Positive_regulation of Phosphorylation of Gja1 1 0.65 0.73 0.73
55 INT139069 Binding of CTLA4 and Cd86 3 0.16 0.65 0.7
56 INT166386 Mapk1 Regulation of Gene_expression of Gnb2l1 1 0.46 0.25 0.7
57 INT320633 Positive_regulation of MAPK1 Regulation of BCL2 1 0.04 1.21 0.7
58 INT194685 MAPK1 Regulation of Gene_expression of IL10 1 0.06 1.18 0.7
59 INT320634 Positive_regulation of MAPK1 Regulation of PBX2 1 0.03 1.21 0.7
60 INT223868 Mapk1 Positive_regulation of Creb1 2 0.17 0.34 0.68
61 INT223876 Mapk1 Positive_regulation of Atf6b 1 0.10 0 0.68
62 INT211916 Fig4 Positive_regulation of Mapk1 1 0.13 0.25 0.66
63 INT191332 AMPH Positive_regulation of Mapk1 1 0.76 0 0.66
64 INT124477 MAP2K1 Positive_regulation of Positive_regulation of MAPK1 1 0.12 1.35 0.65
65 INT148173 Positive_regulation of Grm5 Positive_regulation of Phosphorylation of Mapk1 1 0.01 0.45 0.65
66 INT296785 Tlr9 Regulation of Bcl2 1 0.19 0.76 0.65
67 INT299793 Positive_regulation of Binding of CD86 and CTLA4 1 0.17 1.64 0.63
68 INT299792 Positive_regulation of Binding of CD80 and CTLA4 1 0.17 1.63 0.63
69 INT281092 Adcy1 Positive_regulation of Mapk1 1 0.21 0 0.63
70 INT281090 Prkacb Positive_regulation of Mapk1 1 0.06 0 0.62
71 INT316889 Binding of Cd19 and Cr2 1 0.07 1.7 0.61
72 INT291262 Positive_regulation of INS Positive_regulation of Mapk1 1 0.03 1.78 0.58
73 INT121288 Binding of TAC1 and Cd79a 1 0.12 0.32 0.58
74 INT291258 INS Positive_regulation of Mapk1 1 0.04 1.77 0.58
75 INT115146 MAPK1 Positive_regulation of EGR1 3 0.13 2.43 0.57
76 INT148172 Mapk1 Positive_regulation of Phosphorylation of Kcnd2 1 0.49 0.55 0.57
77 INT31861 Cd79b Regulation of Sst 1 0.49 0.31 0.56
78 INT122427 Ighm Positive_regulation of Positive_regulation of P9Ehs1 1 0.00 0 0.56
79 INT249624 Negative_regulation of Binding of CD86 and CTLA4 1 0.47 0.57 0.55
80 INT201949 CXCL10 Positive_regulation of Phosphorylation of MAPK1 1 0.15 0.79 0.55
81 INT121994 EGF Positive_regulation of Positive_regulation of MAPK1 1 0.25 0 0.55
82 INT323146 PRKCA Positive_regulation of MAPK1 1 0.02 0 0.54
83 INT85125 IL3 Positive_regulation of MAPK1 1 0.30 0.81 0.53
84 INT85121 CSF2 Positive_regulation of MAPK1 1 0.07 0.8 0.53
85 INT85115 IL5 Positive_regulation of MAPK1 1 0.14 0.81 0.53
86 INT219253 Binding of Cd79a and Pigr 2 0.22 0.67 0.52
87 INT171909 MAPK8 Positive_regulation of Gene_expression of MAPK1 1 0.08 1.55 0.52
88 INT171910 MAPK1 Positive_regulation of MAPK9 1 0.10 1.55 0.52
89 INT201939 CXCL10 Positive_regulation of MAPK1 1 0.11 0.72 0.52
90 INT171906 MAPK1 Positive_regulation of Gene_expression of MAPK14 1 0.08 1.55 0.52
91 INT171914 MAPK8IP3 Positive_regulation of Gene_expression of MAPK1 1 0.06 1.55 0.52
92 INT122872 SEMA6A Positive_regulation of MAPK1 1 0.56 0 0.52
93 INT131368 MAPK1 Positive_regulation of Bcar3 1 0.00 0.37 0.51
94 INT131369 MAPK1 Positive_regulation of Il4 1 0.01 0.37 0.51
95 INT299785 CTLA4 Negative_regulation of Binding of CD28 2 0.17 1.8 0.5
96 INT356286 Ngf Regulation of Positive_regulation of Mapk1 1 0.03 0.76 0.5
97 INT356279 Gdnf Regulation of Positive_regulation of Mapk1 1 0.03 0.76 0.5
98 INT122426 Binding of Hint1 and Ighm 1 0.00 0 0.5
99 INT194676 Negative_regulation of MAPK1 Negative_regulation of Gene_expression of IL10 1 0.05 0.34 0.5
100 INT102553 HGF Positive_regulation of Phosphorylation of MAPK1 1 0.40 0.49 0.48
101 INT321045 Anpep Positive_regulation of Protein_catabolism of Ptpn6 1 0.01 0.22 0.48
102 INT151485 Negative_regulation of Binding of Ptpn6 and Oprd1 1 0.00 0 0.47
103 INT173475 Bcar1 Regulation of Isl1 1 0.01 0 0.47
104 INT302839 MIR15A Negative_regulation of Bcl2 1 0.15 1.41 0.47
105 INT151484 Binding of Ptpn6 and Oprd1 1 0.00 0 0.47
106 INT185917 Binding of AR and MAPK1 1 0.07 0.5 0.47
107 INT102555 HGF Positive_regulation of MAPK1 1 0.38 0.47 0.47
108 INT265646 Binding of Mapk1 and Mapk14 1 0.01 1.53 0.46
109 INT331731 Binding of C3 and CD79A 1 0.02 0.85 0.46
110 INT254198 Mapk1 Positive_regulation of Mapk8 1 0.01 0.87 0.46
111 INT254216 Mapk14 Positive_regulation of Mapk1 1 0.02 0.87 0.46
112 INT254222 Mapk1 Positive_regulation of Mapk14 1 0.02 0.86 0.46
113 INT238639 Cd86 Negative_regulation of Negative_regulation of Bcl2 1 0.01 0.97 0.46
114 INT108332 EGF Positive_regulation of Phosphorylation of MAPK1 5 0.48 1.85 0.45
115 INT112772 Binding of Bcl2 and SGSM3 1 0.02 0.69 0.45
116 INT190870 BDNF Positive_regulation of Phosphorylation of Mapk1 1 0.12 0.54 0.44
117 INT343846 MAPK1 Positive_regulation of FOS 1 0.04 1.29 0.44
118 INT223863 Positive_regulation of Mapk1 Positive_regulation of Positive_regulation of Ltp 1 0.31 0 0.43
119 INT264473 Il1a Positive_regulation of Mapk1 1 0.00 0 0.43
120 INT116609 Lnpep Negative_regulation of Bcl2 1 0.05 0.62 0.43
121 INT337326 PIK3CD Positive_regulation of Localization of ITPR3 1 0.02 0 0.43
122 INT188211 IL6 Regulation of MAPK1 1 0.16 1.13 0.43
123 INT337325 PIK3CD Positive_regulation of Phosphorylation of IL2RG 1 0.00 0 0.43
124 INT116606 Lnpep Regulation of Gene_expression of Bcl2 1 0.07 0.62 0.43
125 INT265647 Binding of Ephb1 and Mapk1 1 0.00 1.48 0.43
126 INT337324 PIK3CD Positive_regulation of Gene_expression of ITPR3 1 0.02 0 0.43
127 INT264471 Il1a Positive_regulation of Gene_expression of Mapk1 1 0.01 0 0.43
128 INT116607 Lnpep Negative_regulation of Gene_expression of Bcl2 1 0.10 0.62 0.43
129 INT321047 Anpep Regulation of Negative_regulation of Ptpn6 1 0.01 0.25 0.43
130 INT309143 Dlat Positive_regulation of Bcl2 1 0.06 1.04 0.42
131 INT87556 TPSAB1 Positive_regulation of CD79A 1 0.40 0.7 0.42
132 INT238913 MAPK3 Regulation of Positive_regulation of MAPK1 1 0.11 0.39 0.42
133 INT309152 Dlat Positive_regulation of Gene_expression of Bcl2 1 0.04 1.05 0.42
134 INT161521 Negative_regulation of H2-M3 Positive_regulation of Mapk1 1 0.14 0.41 0.42
135 INT194722 Negative_regulation of MAPK1 Negative_regulation of Gene_expression of CRP 1 0.09 1.49 0.41
136 INT274864 Negative_regulation of Mapk1 Negative_regulation of Gene_expression of TNF 1 0.05 1.15 0.41
137 INT161522 H2-M3 Positive_regulation of Mapk1 1 0.15 0.41 0.41
138 INT274867 Negative_regulation of Mapk1 Negative_regulation of TNF 1 0.03 1.15 0.41
139 INT261652 Binding of MAPK1 and PSEN1 1 0.22 1.25 0.41
140 INT124260 Plat Positive_regulation of Mapk1 1 0.14 0.81 0.41
141 INT194705 Negative_regulation of MAPK1 Negative_regulation of Positive_regulation of IK 1 0.00 1.46 0.41
142 INT113474 MAPK1 Negative_regulation of TNF 1 0.13 0.23 0.4
143 INT157657 Binding of CTLA4 and FCGR1A 1 0.01 0.07 0.4
144 INT152237 Mapk1 Positive_regulation of Localization of Tlr4 1 0.33 0.13 0.39
145 INT152239 Mapk1 Positive_regulation of Localization of Nfkb1 1 0.29 0.13 0.39
146 INT220050 Ctla4 Positive_regulation of Ido1 1 0.31 1.45 0.38
147 INT235878 Creb1 Positive_regulation of Gene_expression of Bcl2 1 0.05 0.17 0.38
148 INT194713 MAPK1 Regulation of Gene_expression of TNF 1 0.10 1.66 0.38
149 INT129768 Binding of LYZ and PTPRC 1 0.34 0.87 0.37
150 INT207643 Prkca Positive_regulation of Mapk1 1 0.09 0.17 0.37
151 INT304501 Binding of Ephb1 and Mapk1 1 0.18 0.69 0.36
152 INT274941 Ephb2 Regulation of Phosphorylation of Mapk1 1 0.19 0 0.36
153 INT155062 Csf2 Positive_regulation of Transcription of Bcl2 1 0.31 2.91 0.36
154 INT304505 Binding of Mapk1 and Uts2d 1 0.01 0.64 0.36
155 INT304532 Binding of Mdk and Mapk1 1 0.02 0.63 0.35
156 INT264555 IL15 Positive_regulation of Gene_expression of BCL2 1 0.02 0.92 0.35
157 INT274865 Positive_regulation of Mapk1 Negative_regulation of Gene_expression of TNF 1 0.04 1.08 0.35
158 INT304495 Trib3 Positive_regulation of Mapk1 1 0.02 1.4 0.35
159 INT304529 Negative_regulation of Binding of Mdk and Mapk1 1 0.02 0.63 0.35
160 INT144966 MAPK1 Positive_regulation of Localization of EGR1 1 0.08 0.83 0.35
161 INT167156 FPR1 Positive_regulation of MAPK1 1 0.18 0.09 0.35
162 INT328043 Binding of PTPRC and Enox2 1 0.00 0.88 0.34
163 INT188193 Negative_regulation of EGF Positive_regulation of MAPK1 1 0.28 0.54 0.34
164 INT173476 Th Regulation of Gene_expression of Bcar1 1 0.10 0 0.34
165 INT328044 Positive_regulation of Binding of PTPRC and Enox2 1 0.00 0.89 0.34
166 INT328045 Binding of PTPRC and Tag 1 0.00 0.88 0.34
167 INT269962 Bcl2 Negative_regulation of Bcl2l11 1 0.15 2.14 0.34
168 INT181451 Lck Regulation of Mbp 1 0.08 1.43 0.34
169 INT23882 Npy Positive_regulation of Bcar1 1 0.34 0.67 0.34
170 INT156831 EGF Positive_regulation of MAPK1 2 0.45 0.27 0.33
171 INT190652 Mdk Positive_regulation of Phosphorylation of Mapk1 2 0.50 0.85 0.33
172 INT274866 Mapk1 Positive_regulation of Gene_expression of TNF 1 0.06 0.35 0.33
173 INT304339 Negative_regulation of CD79A Positive_regulation of NRP2 1 0.06 0.86 0.33
174 INT155060 Stat3 Negative_regulation of Bcl2 1 0.21 3.7 0.33
175 INT167155 FPR1 Positive_regulation of Phosphorylation of MAPK1 1 0.18 0.17 0.33
176 INT337112 Negative_regulation of Nr1d2-rs2 Positive_regulation of Mapk1 1 0.00 0.14 0.33
177 INT139068 Binding of CTLA4 and Cd80 1 0.00 0.33 0.33
178 INT280814 Positive_regulation of Mapk1 Positive_regulation of Transcription of Fos 1 0.02 0.06 0.33
179 INT304338 CD79A Positive_regulation of NRP2 1 0.08 0.84 0.32
180 INT346286 ELANE Positive_regulation of MAPK1 1 0.06 0.65 0.32
181 INT346281 Binding of ELANE and MAPK1 1 0.04 0.65 0.32
182 INT291240 Map3k8 Positive_regulation of Positive_regulation of Mapk1 1 0.16 0.72 0.32
183 INT299791 Negative_regulation of Binding of CD28 and CTLA4 1 0.18 0.77 0.32
184 INT186127 CTLA4 Negative_regulation of CD28 1 0.19 0.74 0.32
185 INT291241 Map3k8 Positive_regulation of Gene_expression of Mapk1 1 0.17 0.72 0.32
186 INT316883 Positive_regulation of Binding of Cd19 and Cd22 1 0.02 0.86 0.31
187 INT286708 Negative_regulation of Mapk1 Negative_regulation of Casp3 1 0.12 0 0.31
188 INT194710 MAPK1 Regulation of Gene_expression of IK 1 0.00 0.24 0.31
189 INT100029 TNF Positive_regulation of Mapk1 1 0.01 0.78 0.31
190 INT337111 Positive_regulation of Nr1d2-rs2 Negative_regulation of Positive_regulation of Mapk1 1 0.00 0.15 0.31
191 INT316881 Positive_regulation of Binding of Cd19 and Bcr 1 0.08 0.86 0.31
192 INT316887 Binding of Cd19 and Cd22 1 0.02 0.85 0.31
193 INT170496 Egf Positive_regulation of Mapk1 3 0.21 0.5 0.3
194 INT112797 Positive_regulation of CASP1 Positive_regulation of MAPK1 1 0.02 0.16 0.3
195 INT242398 Cyp19a1 Positive_regulation of Bcl2 1 0.00 1.28 0.3
196 INT356287 Ngf Positive_regulation of Mapk1 1 0.05 0.17 0.3
197 INT316888 Binding of Cd19 and Bcr 1 0.08 0.85 0.3
198 INT304504 Mapk1 Positive_regulation of Nos1 1 0.29 0.93 0.3
199 INT356278 Gdnf Positive_regulation of Mapk1 1 0.05 0.17 0.3
200 INT286702 Positive_regulation of Mapk1 Positive_regulation of Positive_regulation of Rps6ka5 1 0.37 0.18 0.29

Single Events

The table below shows the top 100 pain related interactions that have been reported for B cell receptor signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported in B cell receptor signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT95787 Positive_regulation of Mapk1 568 0.70 226.51 220.94
2 INT71789 Positive_regulation of MAPK1 396 0.70 234.44 89.27
3 INT92434 Phosphorylation of Mapk1 287 0.82 91.65 83.46
4 INT48934 Positive_regulation of Mapk1 157 0.70 60.61 61.72
5 INT82650 Gene_expression of Bcl2 312 0.78 211.71 55.03
6 INT71786 Phosphorylation of MAPK1 256 0.82 110.09 46.17
7 INT92437 Positive_regulation of Phosphorylation of Mapk1 113 0.70 32.19 40.29
8 INT114751 Gene_expression of Mapk1 137 0.76 60.14 39.98
9 INT102611 Negative_regulation of Positive_regulation of Mapk1 74 0.58 35.57 39.37
10 INT77307 Gene_expression of Bcl2 399 0.77 319.77 38
11 INT109434 Phosphorylation of Mapk1 110 0.82 61.64 34.05
12 INT48925 Gene_expression of Mapk1 95 0.74 42.21 32.91
13 INT117112 Negative_regulation of Mapk1 87 0.56 40.34 31.18
14 INT65960 Gene_expression of BCL2 352 0.78 312.03 30.73
15 INT83708 Negative_regulation of MAPK1 156 0.57 84.93 27.85
16 INT95788 Positive_regulation of Positive_regulation of Mapk1 83 0.69 24.75 25.84
17 INT12124 Gene_expression of MAPK1 141 0.75 82.4 25.58
18 INT91462 Positive_regulation of Phosphorylation of MAPK1 99 0.67 40.28 18.99
19 INT93734 Positive_regulation of Gene_expression of Bcl2 76 0.70 61.95 18.46
20 INT86673 Positive_regulation of Bcl2 77 0.70 57.74 17.37
21 INT2120 Gene_expression of CD79A 159 0.78 111.69 17.16
22 INT95790 Regulation of Mapk1 55 0.61 21.17 16.31
23 INT111462 Negative_regulation of Phosphorylation of Mapk1 45 0.57 19.49 15.59
24 INT75531 Regulation of MAPK1 70 0.61 34.39 15.42
25 INT128401 Positive_regulation of Positive_regulation of Mapk1 39 0.70 10.88 15.38
26 INT80688 Positive_regulation of Positive_regulation of MAPK1 72 0.69 39.35 14.11
27 INT3796 Gene_expression of Ighm 130 0.77 69.61 13.78
28 INT80222 Negative_regulation of Bcl2 82 0.58 69.16 13.18
29 INT150676 Positive_regulation of Gene_expression of Mapk1 30 0.45 10.06 12.37
30 INT119396 Regulation of Positive_regulation of Mapk1 22 0.61 7.88 12.25
31 INT148207 Gene_expression of CTLA4 53 0.77 29.13 12.07
32 INT81640 Positive_regulation of Gene_expression of Bcl2 106 0.69 84.58 11.63
33 INT69029 Gene_expression of PTPRC 127 0.75 74.26 11.57
34 INT75525 Negative_regulation of Positive_regulation of MAPK1 40 0.59 25.15 11.15
35 INT48921 Regulation of Mapk1 25 0.49 19.51 10.41
36 INT94196 Negative_regulation of Phosphorylation of MAPK1 60 0.59 31.64 9.16
37 INT109432 Negative_regulation of Phosphorylation of Mapk1 19 0.54 7.01 8.98
38 INT70017 Positive_regulation of BCL2 87 0.67 66.62 8.68
39 INT86672 Negative_regulation of Bcl2 50 0.53 34.16 8.37
40 INT126848 Positive_regulation of Phosphorylation of Mapk1 30 0.50 15.94 8.34
41 INT65959 Positive_regulation of Gene_expression of BCL2 75 0.70 77.3 8.27
42 INT132278 Binding of CTLA4 32 0.39 18.69 8.17
43 INT18736 Gene_expression of Ptpn6 19 0.59 4.44 8.06
44 INT80220 Positive_regulation of Bcl2 71 0.58 57.73 7.86
45 INT77306 Negative_regulation of Gene_expression of Bcl2 46 0.58 38.05 7.71
46 INT91445 Regulation of Bcl2 50 0.56 38.8 7.41
47 INT120401 Positive_regulation of PIK3CD 33 0.45 14.89 7.37
48 INT9491 Positive_regulation of Ptpn6 11 0.51 2.33 7.32
49 INT1123 Positive_regulation of CD79A 74 0.70 51.96 7.14
50 INT76120 Gene_expression of Ptprc 102 0.59 30.42 7.02
51 INT93101 Regulation of Gene_expression of Bcl2 26 0.62 18.45 6.71
52 INT84685 Regulation of BCL2 67 0.60 72.96 6.65
53 INT48928 Positive_regulation of Gene_expression of Mapk1 19 0.48 9.38 6.59
54 INT3795 Positive_regulation of Ighm 46 0.68 22.43 6.47
55 INT38595 Localization of BCAR1 8 0.73 2.9 6.25
56 INT139964 Regulation of Phosphorylation of Mapk1 12 0.58 10.04 6.1
57 INT39416 Gene_expression of Cd79a 81 0.64 45.17 6.08
58 INT1126 Negative_regulation of CD79A 46 0.59 31.07 6
59 INT130111 Regulation of Positive_regulation of MAPK1 14 0.36 11.01 5.9
60 INT100422 Negative_regulation of Gene_expression of Bcl2 46 0.58 28.86 5.7
61 INT50975 Localization of Ptpn6 8 0.65 2.64 5.7
62 INT71779 Positive_regulation of Gene_expression of MAPK1 27 0.47 21.41 5.39
63 INT76313 Gene_expression of CD38 30 0.64 20.74 5.27
64 INT70613 Negative_regulation of Gene_expression of BCL2 48 0.59 38.91 5.22
65 INT73262 Negative_regulation of BCL2 67 0.57 61.01 5.07
66 INT1807 Negative_regulation of Bcar1 9 0.38 4.04 4.59
67 INT101957 Transcription of Bcl2 30 0.69 16.57 4.3
68 INT110343 Negative_regulation of PIK3CD 22 0.40 5.84 4.2
69 INT158416 Localization of Mapk1 19 0.67 5.32 4.18
70 INT133244 Regulation of Positive_regulation of Mapk1 11 0.43 3.52 4.03
71 INT3405 Gene_expression of BCAR1 14 0.71 8.89 4.02
72 INT113924 Binding of Mapk1 27 0.38 8.64 3.84
73 INT146946 Gene_expression of Lyn 16 0.76 8.9 3.75
74 INT105882 Phosphorylation of Bcl2 11 0.59 8.15 3.73
75 INT36799 Negative_regulation of Ighm 21 0.41 17.47 3.65
76 INT78284 Positive_regulation of PTPRC 40 0.49 27.17 3.45
77 INT6339 Negative_regulation of Ptpn6 6 0.14 0.71 3.44
78 INT109403 Regulation of Gene_expression of BCL2 31 0.60 31.22 3.4
79 INT3403 Positive_regulation of BCAR1 18 0.63 18.95 3.23
80 INT157401 Gene_expression of Ctla4 21 0.65 15.43 3.2
81 INT81642 Regulation of Gene_expression of Bcl2 20 0.44 16.93 3.19
82 INT64 Regulation of Ptpn6 12 0.14 2.45 3.17
83 INT64234 Regulation of Bcl2 41 0.54 31.88 3.16
84 INT171368 Regulation of Phosphorylation of Mapk1 14 0.61 4.77 3.14
85 INT38594 Positive_regulation of Localization of BCAR1 3 0.63 0.44 3.07
86 INT9884 Localization of CD79A 41 0.78 21.75 3.06
87 INT43907 Binding of CD79A 28 0.48 28.11 3.04
88 INT105884 Binding of Bcl2 19 0.35 15.67 3
89 INT200895 Localization of Mapk1 6 0.67 2.08 2.82
90 INT169112 Negative_regulation of Positive_regulation of Mapk1 9 0.59 1.84 2.78
91 INT145821 Negative_regulation of Gene_expression of Mapk1 16 0.41 8.05 2.77
92 INT161310 Negative_regulation of LCK 17 0.42 8.75 2.74
93 INT152927 Negative_regulation of Mapk1 16 0.41 5.85 2.73
94 INT321018 Protein_catabolism of Ptpn6 1 0.14 0.52 2.73
95 INT98226 Negative_regulation of Cd79a 5 0.49 3.99 2.66
96 INT87340 Negative_regulation of BCAR1 8 0.38 6.96 2.63
97 INT191017 Localization of Cd79a 28 0.56 13.94 2.55
98 INT187454 Binding of Ptprc 34 0.38 9.66 2.54
99 INT137616 Gene_expression of Cd38 19 0.67 9.37 2.54
100 INT61378 Positive_regulation of Bcar1 13 0.45 2.84 2.45
101 INT230758 Positive_regulation of Gene_expression of PTPRC 11 0.49 6.04 2.45
102 INT67796 Negative_regulation of CTLA4 13 0.39 8.36 2.39
103 INT186116 Regulation of Gene_expression of MAPK1 9 0.44 5.85 2.32
104 INT147349 Localization of Bcl2 13 0.65 7.83 2.31
105 INT146945 Positive_regulation of Lyn 6 0.49 2.81 2.25
106 INT142677 Negative_regulation of Positive_regulation of Bcl2 4 0.36 3.09 2.24
107 INT24740 Positive_regulation of Cd79a 36 0.48 14.71 2.17
108 INT137629 Binding of Ptpn6 10 0.30 0.42 2.15
109 INT321023 Positive_regulation of Localization of Ptpn6 1 0.07 0.27 2.15
110 INT122671 Positive_regulation of LCK 4 0.13 2.69 2.14
111 INT264967 Positive_regulation of Positive_regulation of PIK3CD 4 0.18 1.97 2.13
112 INT170482 Regulation of Gene_expression of Mapk1 5 0.43 5.73 2.1
113 INT278340 Gene_expression of Syk 7 0.51 4.92 2.09
114 INT86671 Negative_regulation of Positive_regulation of Bcl2 6 0.57 3.83 2.03
115 INT3797 Positive_regulation of Gene_expression of Ighm 16 0.47 9.4 2.01
116 INT109906 Localization of MAPK1 12 0.54 1.68 2.01
117 INT83709 Negative_regulation of Gene_expression of MAPK1 12 0.41 6.57 2.01
118 INT204139 Positive_regulation of Gene_expression of BCAR1 1 0.23 0.9 1.96
119 INT117934 Gene_expression of Cd38 11 0.68 6.5 1.95
120 INT61148 Regulation of Cd79a 13 0.51 6.95 1.9
121 INT101108 Localization of Bcl2 16 0.72 11.68 1.86
122 INT105883 Positive_regulation of Phosphorylation of Bcl2 8 0.32 5.67 1.86
123 INT99416 Negative_regulation of Bcar1 1 0.34 0.64 1.84
124 INT20207 Binding of Ighm 14 0.46 2.88 1.79
125 INT98224 Negative_regulation of Gene_expression of Cd79a 6 0.35 3.35 1.74
126 INT56100 Negative_regulation of Gene_expression of Ighm 5 0.48 2.07 1.72
127 INT23881 Gene_expression of Bcar1 8 0.52 2.48 1.69
128 INT38266 Localization of PTPRC 30 0.68 17.05 1.68
129 INT101958 Positive_regulation of Transcription of Bcl2 4 0.50 2.22 1.65
130 INT137513 Negative_regulation of Positive_regulation of BCL2 6 0.35 5.3 1.62
131 INT206528 Negative_regulation of Gene_expression of Ptprc 8 0.34 3.91 1.61
132 INT169461 Regulation of Gene_expression of Mapk1 7 0.44 1.64 1.61
133 INT57336 Gene_expression of Cd19 5 0.46 4.8 1.6
134 INT22329 Gene_expression of Ptprc 36 0.66 15.84 1.59
135 INT45230 Regulation of CD79A 20 0.44 9.3 1.59
136 INT168860 Positive_regulation of Cd38 5 0.70 4.07 1.57
137 INT243799 Gene_expression of PIK3CD 15 0.45 6.63 1.5
138 INT130019 Regulation of Phosphorylation of MAPK1 6 0.49 3.6 1.5
139 INT19432 Positive_regulation of Gene_expression of CD79A 14 0.45 13.49 1.49
140 INT29856 Negative_regulation of Positive_regulation of Ptpn6 3 0.38 1.24 1.47
141 INT168861 Positive_regulation of Gene_expression of Cd38 2 0.50 2.01 1.47
142 INT128478 Positive_regulation of Ptprc 26 0.44 8.1 1.45
143 INT122672 Regulation of Positive_regulation of LCK 1 0.06 1.15 1.44
144 INT190646 Regulation of Regulation of Mapk1 1 0.30 1.16 1.43
145 INT153627 Binding of Mapk1 5 0.36 2.88 1.4
146 INT143083 Regulation of CTLA4 4 0.25 1.06 1.36
147 INT104027 Negative_regulation of Negative_regulation of MAPK1 6 0.56 2.87 1.35
148 INT3404 Binding of BCAR1 10 0.33 7.97 1.33
149 INT168859 Regulation of Cd38 1 0.27 0.11 1.33
150 INT101107 Positive_regulation of Localization of Bcl2 3 0.48 3.13 1.28
151 INT90771 Positive_regulation of Ptprc 20 0.48 8.43 1.27
152 INT74254 Binding of PTPRC 16 0.36 8.37 1.27
153 INT37253 Negative_regulation of PTPRC 12 0.37 6.13 1.26
154 INT117933 Positive_regulation of Gene_expression of Cd38 3 0.38 1.62 1.23
155 INT206515 Regulation of Gene_expression of Ptprc 6 0.39 3.4 1.22
156 INT168864 Positive_regulation of Positive_regulation of Cd38 1 0.47 0.05 1.18
157 INT314388 Positive_regulation of Gene_expression of Ptpn6 3 0.11 0.05 1.15
158 INT321016 Regulation of Positive_regulation of Ptpn6 1 0.05 0.05 1.15
159 INT264969 Localization of PIK3CD 5 0.50 0.64 1.13
160 INT321020 Regulation of Protein_catabolism of Ptpn6 1 0.06 0.05 1.12
161 INT172855 Binding of Bcl2 37 0.32 23.41 1.09
162 INT70021 Localization of BCL2 23 0.74 21.6 1.09
163 INT183820 Regulation of BCAR1 4 0.39 3.27 1.06
164 INT191018 Positive_regulation of Gene_expression of Cd79a 12 0.26 8.01 1.05
165 INT274898 Positive_regulation of Positive_regulation of Lyn 1 0.35 1.51 1.05
166 INT193069 Positive_regulation of Gene_expression of CD38 4 0.15 4.06 1.01
167 INT147464 Binding of Ptprc 13 0.36 15.18 0.98
168 INT248588 Gene_expression of LCK 9 0.28 4.9 0.98
169 INT126672 Binding of Bcar1 7 0.20 2.67 0.98
170 INT275940 Negative_regulation of Syk 3 0.39 2.08 0.95
171 INT146939 Negative_regulation of Lyn 3 0.53 2.97 0.95
172 INT62031 Gene_expression of Cd19 27 0.65 10.39 0.93
173 INT204136 Regulation of Gene_expression of BCAR1 2 0.21 0.62 0.93
174 INT122422 Negative_regulation of Phosphorylation of Ighm 1 0.01 0 0.91
175 INT149383 Binding of Lyn 1 0.36 1.14 0.91
176 INT294150 Regulation of Gene_expression of PTPRC 6 0.32 3.3 0.88
177 INT151115 Regulation of Regulation of Bcl2 4 0.21 4.12 0.88
178 INT277586 Negative_regulation of Mef2c 36 0.59 11.03 0.86
179 INT92117 Phosphorylation of BCL2 26 0.80 9.93 0.86
180 INT192404 Localization of Ighm 15 0.48 5.8 0.85
181 INT122425 Phosphorylation of Ighm 1 0.01 0 0.85
182 INT126572 Positive_regulation of SYK 3 0.67 2.98 0.83
183 INT161311 Positive_regulation of Negative_regulation of LCK 2 0.45 0.74 0.83
184 INT146942 Gene_expression of Lck 1 0.46 1.3 0.83
185 INT145986 Positive_regulation of CTLA4 8 0.56 2.66 0.82
186 INT254253 Transcription of Ighm 5 0.45 3.6 0.81
187 INT206007 Positive_regulation of Localization of Cd79a 5 0.35 3.32 0.81
188 INT94743 Regulation of Ctla4 1 0.44 1.28 0.8
189 INT70019 Binding of BCL2 25 0.47 17.55 0.79
190 INT109404 Transcription of BCL2 6 0.69 4.49 0.77
191 INT108044 Phosphorylation of Syk 3 0.25 1.39 0.77
192 INT194780 Regulation of Negative_regulation of MAPK1 3 0.32 3.42 0.76
193 INT124844 Regulation of Positive_regulation of Bcl2 3 0.43 2.55 0.75
194 INT155392 Negative_regulation of Negative_regulation of Bcl2 3 0.21 1.64 0.74
195 INT134444 Positive_regulation of Binding of Bcl2 3 0.47 2.67 0.72
196 INT122670 Negative_regulation of Positive_regulation of LCK 1 0.06 0.58 0.72
197 INT202361 Gene_expression of Mef2c 28 0.78 5.53 0.67
198 INT102655 Positive_regulation of Positive_regulation of Ighm 2 0.32 0.74 0.67
199 INT157491 Negative_regulation of Ctla4 5 0.31 2.68 0.63
200 INT321017 Negative_regulation of Protein_catabolism of Ptpn6 1 0.08 0.19 0.63
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