GO:0050869

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Name negative regulation of B cell activation
Categary Process
Go Slim No
Go Link GO:0050869
Unique Molecular Interactions 101
Total Molecular Interactions 143
Total Single Events 1467
Pain Genes Associated 8

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of B cell activation. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of B cell activation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT139190 Binding of Fadd and Fas 4 0.38 2.65 1.71
2 INT139191 Binding of Fas and RFFL 1 0.00 0.61 1.22
3 INT139188 Binding of Daxx and Fas 1 0.03 0.55 1.14
4 INT91813 Binding of FAS and FASLG 4 0.23 9.89 0.99
5 INT133617 Fas Positive_regulation of Fadd 1 0.48 0.07 0.96
6 INT130769 FASLG Negative_regulation of Binding of FAS 1 0.10 0.66 0.86
7 INT228499 Binding of FAS and Fasl 1 0.15 2.75 0.73
8 INT81631 Selenbp2 Negative_regulation of Fas 1 0.03 0.77 0.67
9 INT81630 Selenbp2 Negative_regulation of Positive_regulation of Fas 1 0.03 0.77 0.67
10 INT115592 IRF6 Positive_regulation of Gene_expression of FAS 1 0.34 0.34 0.62
11 INT139192 RFFL Positive_regulation of Fas 1 0.00 0.3 0.61
12 INT80030 Binding of FAS and TNF 3 0.27 2.54 0.56
13 INT160780 Cps1 Positive_regulation of Positive_regulation of FAS 1 0.01 1 0.55
14 INT292873 Binding of Fas and Fasl 5 0.26 15.74 0.49
15 INT158599 Tlr3 Positive_regulation of Binding of Fas 1 0.55 0.86 0.48
16 INT355018 Binding of FAS and Faslg 1 0.12 1.34 0.37
17 INT263978 Binding of ADRB2 and TNFAIP3 1 0.01 0.5 0.32
18 INT332972 Fas Positive_regulation of Ppara 1 0.17 0.52 0.31
19 INT80029 Binding of FAS and Positive_regulation of NFKB1 1 0.34 0.92 0.3
20 INT80031 FAS Positive_regulation of Positive_regulation of NFKB1 1 0.50 0.93 0.3
21 INT239336 Nr1h2 Positive_regulation of Gene_expression of Fas 1 0.07 0.84 0.29
22 INT228500 Fadd Positive_regulation of FAS 1 0.14 1.12 0.28
23 INT93352 Ifng Positive_regulation of Positive_regulation of Fas 1 0.26 0.17 0.27
24 INT237928 BCL2 Positive_regulation of FAS 1 0.02 1.41 0.26
25 INT149713 Binding of Casp3 and Fas 1 0.40 1.09 0.25
26 INT171049 Binding of FAS and Positive_regulation of Gene_expression of CASP3 1 0.04 1.41 0.24
27 INT88023 Tnf Negative_regulation of Gene_expression of Fas 1 0.29 0.74 0.22
28 INT88025 Ifng Negative_regulation of Gene_expression of Fas 1 0.32 0.74 0.22
29 INT148533 Binding of Alb and Fas 1 0.23 0.08 0.21
30 INT343849 Binding of FAS and TLR4 1 0.04 0.32 0.21
31 INT301615 Binding of Cyp2e1 and Samsn1 1 0.02 2.42 0.18
32 INT229223 Binding of AGT and FAS 1 0.08 0.91 0.17
33 INT229245 Positive_regulation of Binding of FAS and Tnf 1 0.25 0.92 0.17
34 INT229246 Binding of FAS and Tnf 1 0.19 0.91 0.17
35 INT229224 Positive_regulation of Binding of AGT and FAS 1 0.09 0.92 0.17
36 INT175328 FASLG Positive_regulation of FAS 1 0.01 0.9 0.17
37 INT91811 Binding of FAS and TP53 1 0.21 1.1 0.16
38 INT171871 Binding of FAS and Sumo1 1 0.02 1.43 0.16
39 INT348012 Samsn1 Positive_regulation of Vps54 1 0.00 1.93 0.15
40 INT332966 Binding of Fas and Ppara 1 0.15 0.25 0.13
41 INT318993 Hand1 Positive_regulation of Gene_expression of Fas 1 0.03 0.76 0.12
42 INT318995 IFN1@ Positive_regulation of Gene_expression of Fas 1 0.23 0.76 0.12
43 INT348011 Binding of Samsn1 and Vps54 1 0.00 1.35 0.11
44 INT273063 Negative_regulation of Fas Negative_regulation of Positive_regulation of Bcl2 1 0.01 0.72 0.11
45 INT143648 Negative_regulation of Mapk8 Negative_regulation of Gene_expression of Fas 1 0.39 0.21 0.11
46 INT299015 Binding of FAS and Il18 1 0.38 0.83 0.11
47 INT347647 Inpp5d Negative_regulation of Pik3r1 1 0.31 0.37 0.1
48 INT277091 VEGFA Positive_regulation of Fas 1 0.03 1.72 0.09
49 INT303124 Binding of Fas and Tnfrsf10b 1 0.09 1.03 0.08
50 INT232897 Binding of Rab27a and SAMSN1 1 0.00 0.73 0.08
51 INT307217 Fas Positive_regulation of Agpat2 1 0.06 0.27 0.07
52 INT176257 Positive_regulation of p53-ps Positive_regulation of Gene_expression of Fas 1 0.04 0.32 0.06
53 INT335713 Binding of FAS and CD8A 1 0.32 0.9 0.06
54 INT335711 INCENP Positive_regulation of Gene_expression of FAS 1 0.04 1.42 0.06
55 INT335714 Binding of FAS and CD4 1 0.38 0.9 0.06
56 INT260728 Binding of Samsn1 and NAFLD2 1 0.00 1.15 0.05
57 INT143647 Negative_regulation of Mapk8ip1 Negative_regulation of Gene_expression of Fas 1 0.02 0.15 0.05
58 INT252797 ROS1 Positive_regulation of Positive_regulation of FAS 1 0.08 1.03 0.04
59 INT201745 Negative_regulation of Ngf Positive_regulation of Gene_expression of Fas 1 0.03 0.56 0.04
60 INT201735 Ngf Positive_regulation of Gene_expression of Fas 1 0.03 0.56 0.04
61 INT307209 Fas Positive_regulation of Fasn 1 0.05 0.13 0.03
62 INT176283 Fasl Positive_regulation of Fas 1 0.21 0.3 0.03
63 INT292871 Binding of Fas and Tg(MMTV-Notch4)3Rnc 1 0.05 1.25 0.03
64 INT322876 Binding of PDCD10 and Inpp5d 1 0.03 0.46 0.03
65 INT323703 FADD Positive_regulation of FAS 1 0.26 0.75 0
66 INT241588 Binding of FAS and Fas 1 0.05 2.34 0
67 INT176259 p53-ps Positive_regulation of Transcription of Fas 1 0.04 0.35 0
68 INT269944 Gata6 Regulation of Gene_expression of Foxj1 1 0.19 0 0
69 INT210163 Binding of FAS and TXN 1 0.19 0 0
70 INT351951 Negative_regulation of Binding of Fas and Fasl 1 0.29 1.13 0
71 INT204076 HP Positive_regulation of Gene_expression of Fas 1 0.00 1.81 0
72 INT142932 Binding of Arid1a and Samsn1 1 0.01 1.55 0
73 INT269933 Foxa2 Regulation of Gene_expression of Foxj1 1 0.27 0 0
74 INT268098 Binding of FAS and PDSS1 1 0.03 0.34 0
75 INT268093 Binding of FAS and CYP4F3 1 0.01 0.35 0
76 INT267256 Binding of FAS and Fadd 1 0.11 1.14 0
77 INT176258 p53-ps Regulation of Fas 1 0.03 0.06 0
78 INT268097 Binding of FAS and ACCS 1 0.02 0.4 0
79 INT268094 Binding of FAS and IFNW1 1 0.01 0.35 0
80 INT323705 Binding of FAS and FAF1 1 0.42 1.46 0
81 INT269939 Foxa1 Regulation of Gene_expression of Foxj1 1 0.26 0 0
82 INT176256 p53-ps Positive_regulation of Localization of Fas 1 0.04 0.35 0
83 INT304208 Ufm1 Positive_regulation of Fas 1 0.01 0.51 0
84 INT308745 Binding of Alb and Fas 1 0.00 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of B cell activation. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of B cell activation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT70614 Gene_expression of FAS 118 0.75 112.33 19.01
2 INT77620 Gene_expression of Fas 146 0.78 72.4 16.61
3 INT81627 Gene_expression of Fas 120 0.78 115.51 15.36
4 INT81629 Positive_regulation of Fas 58 0.70 59.63 12.94
5 INT88020 Positive_regulation of Fas 32 0.70 19.78 9.97
6 INT80036 Positive_regulation of FAS 42 0.67 42.22 9.4
7 INT80034 Positive_regulation of Gene_expression of FAS 32 0.67 30.34 8.51
8 INT88014 Positive_regulation of Gene_expression of Fas 29 0.50 14.84 7.47
9 INT80033 Binding of FAS 37 0.48 41.19 5.67
10 INT113516 Negative_regulation of Fas 16 0.51 8.37 5.32
11 INT113517 Binding of Fas 16 0.37 15.86 4.62
12 INT89963 Regulation of Fas 15 0.59 8.25 4.32
13 INT81628 Positive_regulation of Gene_expression of Fas 32 0.67 38.13 4.23
14 INT115889 Binding of Fas 27 0.36 28.87 4.08
15 INT89966 Negative_regulation of Fas 26 0.58 24.83 3.5
16 INT88017 Regulation of Fas 12 0.62 8.27 2.29
17 INT152174 Negative_regulation of Samsn1 5 0.14 6.46 2.1
18 INT77621 Regulation of Gene_expression of Fas 10 0.56 7.62 2.08
19 INT98132 Regulation of FAS 16 0.42 20.57 2.06
20 INT102176 Transcription of FAS 3 0.60 3.22 2.05
21 INT113515 Positive_regulation of Positive_regulation of Fas 4 0.69 0.95 1.92
22 INT121784 Regulation of Gene_expression of Fas 7 0.38 5.68 1.86
23 INT97750 Positive_regulation of Positive_regulation of FAS 4 0.49 4.9 1.8
24 INT199222 Gene_expression of SAMSN1 14 0.57 18.97 1.61
25 INT89965 Transcription of Fas 5 0.71 5.28 1.45
26 INT188404 Positive_regulation of Binding of Fas 3 0.15 5.22 1.37
27 INT130773 Regulation of Gene_expression of FAS 5 0.37 6.87 1.32
28 INT136574 Regulation of TNFAIP3 2 0.11 1.33 1.3
29 INT115108 Negative_regulation of Gene_expression of FAS 9 0.57 9.16 1.23
30 INT139183 Regulation of Binding of Fas 3 0.43 2.5 1.23
31 INT89967 Negative_regulation of Gene_expression of Fas 19 0.58 19.28 1.1
32 INT161369 Protein_catabolism of FAS 1 0.86 1.23 1
33 INT121785 Regulation of Transcription of Fas 1 0.23 0.73 0.96
34 INT156976 Gene_expression of TNFAIP3 4 0.65 5.25 0.93
35 INT199226 Positive_regulation of SAMSN1 6 0.57 10.2 0.9
36 INT112694 Negative_regulation of Positive_regulation of Fas 5 0.42 4.3 0.89
37 INT94546 Transcription of Fas 13 0.56 6.99 0.88
38 INT130772 Positive_regulation of Transcription of FAS 1 0.24 0.67 0.87
39 INT250645 Gene_expression of Samsn1 6 0.33 9.95 0.86
40 INT347182 Negative_regulation of TNFAIP3 3 0.23 5.6 0.84
41 INT202683 Localization of FAS 6 0.73 5.86 0.8
42 INT143482 Negative_regulation of Gene_expression of Fas 20 0.41 8.3 0.79
43 INT117031 Binding of Samsn1 6 0.21 6.82 0.76
44 INT120494 Protein_catabolism of Fas 3 0.88 0.91 0.69
45 INT139180 Regulation of Positive_regulation of Fas 2 0.43 2.19 0.69
46 INT94548 Localization of Fas 9 0.77 5.15 0.65
47 INT264003 Positive_regulation of Transcription of TNFAIP3 1 0.38 1.01 0.65
48 INT263996 Transcription of TNFAIP3 1 0.39 0.99 0.64
49 INT188403 Positive_regulation of Positive_regulation of Fas 3 0.46 4.47 0.63
50 INT199225 Localization of SAMSN1 1 0.62 6.07 0.57
51 INT139181 Positive_regulation of Regulation of Fas 1 0.45 0.25 0.56
52 INT100822 Localization of Fas 8 0.74 6.13 0.48
53 INT158829 Negative_regulation of FAS 5 0.41 4.12 0.48
54 INT163361 Negative_regulation of SAMSN1 2 0.42 6.6 0.43
55 INT135804 Positive_regulation of Negative_regulation of Fas 2 0.56 1.24 0.36
56 INT330616 Positive_regulation of Gene_expression of Inpp5d 2 0.49 0.89 0.34
57 INT157416 Positive_regulation of Samsn1 6 0.53 4.28 0.33
58 INT158828 Positive_regulation of Phosphorylation of FAS 1 0.40 0.58 0.33
59 INT330615 Gene_expression of Inpp5d 2 0.66 0.78 0.31
60 INT202684 Positive_regulation of Localization of FAS 1 0.33 2.46 0.31
61 INT158824 Phosphorylation of FAS 2 0.48 1.41 0.29
62 INT169996 Positive_regulation of Negative_regulation of Fas 2 0.25 1.69 0.28
63 INT170860 Localization of Samsn1 2 0.23 1.16 0.27
64 INT199224 Negative_regulation of Positive_regulation of SAMSN1 3 0.48 4.77 0.25
65 INT199221 Binding of SAMSN1 2 0.29 2.36 0.24
66 INT252717 Positive_regulation of Gene_expression of SAMSN1 1 0.03 1.53 0.24
67 INT330612 Positive_regulation of Localization of Inpp5d 1 0.02 0.35 0.22
68 INT330610 Localization of Inpp5d 1 0.02 0.3 0.22
69 INT95638 Regulation of Binding of FAS 1 0.44 3.08 0.2
70 INT347641 Regulation of Positive_regulation of Inpp5d 1 0.27 0.33 0.19
71 INT323137 Phosphorylation of Fas 1 0.01 0.62 0.19
72 INT100820 Positive_regulation of Localization of Fas 1 0.54 0.85 0.19
73 INT347643 Positive_regulation of Inpp5d 1 0.46 0.33 0.18
74 INT238503 Positive_regulation of Regulation of FAS 1 0.41 4.39 0.18
75 INT176266 Negative_regulation of Negative_regulation of Fas 2 0.22 0.33 0.17
76 INT201513 Positive_regulation of Binding of FAS 2 0.50 2.63 0.16
77 INT181470 Regulation of Transcription of Fas 1 0.28 1.25 0.15
78 INT323231 Positive_regulation of Binding of Samsn1 1 0.18 0.55 0.14
79 INT329979 Negative_regulation of Binding of Fas 2 0.31 3.51 0.1
80 INT199228 Regulation of Gene_expression of SAMSN1 1 0.37 1.48 0.1
81 INT256871 Regulation of Regulation of Fas 1 0.22 0.06 0.08
82 INT212892 Negative_regulation of Binding of Fas 1 0.23 1.68 0.07
83 INT277082 Protein_catabolism of Fas 1 0.37 1.48 0.07
84 INT89964 Negative_regulation of Transcription of Fas 3 0.58 2.62 0.06
85 INT176279 Negative_regulation of Localization of Fas 1 0.34 0.27 0.04
86 INT217333 Positive_regulation of TNFAIP3 3 0.23 2.65 0
87 INT268101 Negative_regulation of Binding of FAS 1 0.34 0.41 0
88 INT348456 Protein_catabolism of TNFAIP3 1 0.22 1.13 0
89 INT348453 Positive_regulation of Positive_regulation of TNFAIP3 1 0.17 1.06 0
90 INT269905 Positive_regulation of Foxj1 1 0.32 0.08 0
91 INT234714 Positive_regulation of Transcription of Fas 1 0.23 0 0
92 INT350662 Regulation of Inpp5d 1 0.06 0.16 0
93 INT157415 Regulation of Positive_regulation of Samsn1 1 0.35 0 0
94 INT269900 Gene_expression of Foxj1 1 0.49 0.25 0
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