GO:0050878

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Name regulation of body fluid levels
Categary Process
Go Slim No
Go Link GO:0050878
Unique Molecular Interactions 86
Total Molecular Interactions 120
Total Single Events 1396
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for regulation of body fluid levels. They are ordered first by their pain relevance and then by number of times they were reported for regulation of body fluid levels. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT114126 Binding of APLNR and OPRL1 1 0.01 0.47 2.85
2 INT107812 Nppa Positive_regulation of Localization of Sst 1 0.48 0.54 2.51
3 INT144213 Nppa Positive_regulation of Localization of Calca 1 0.71 2.8 1.65
4 INT107815 Gene_expression of Sst Positive_regulation of Localization of Nppa 1 0.52 0.27 1.57
5 INT107813 Sst Negative_regulation of Localization of Nppa 1 0.44 0.2 1.46
6 INT31772 Ednra Positive_regulation of Nppa 1 0.05 0.13 1.33
7 INT31771 Penk Positive_regulation of Nppa 1 0.22 0.13 1.28
8 INT31773 Pdyn Positive_regulation of Nppa 1 0.12 0.13 1.27
9 INT62596 Binding of Edn1 and Nppa 1 0.27 1.77 1.22
10 INT125284 FSCN1 Positive_regulation of Positive_regulation of EPHB2 1 0.04 0.4 1.14
11 INT107810 Sst Positive_regulation of Localization of Nppa 1 0.42 0.14 0.77
12 INT97202 Binding of APLNR and Pnoc 1 0.02 0.27 0.63
13 INT16412 Nppa Negative_regulation of Localization of LH 2 0.41 0.29 0.62
14 INT147049 CB Positive_regulation of Nppa 1 0.02 1.01 0.6
15 INT101216 Pnoc Positive_regulation of Localization of Nppa 1 0.68 0.09 0.57
16 INT147040 Hmbs Negative_regulation of Nppa 1 0.07 0.95 0.55
17 INT107814 Nppa Positive_regulation of Positive_regulation of Sst 1 0.42 0.16 0.55
18 INT16643 Nppa Regulation of Rabep2 1 0.13 0.07 0.55
19 INT120383 PRKCD Positive_regulation of Localization of EPHB2 1 0.29 0.42 0.52
20 INT108329 EGF Positive_regulation of Phosphorylation of EPHB2 4 0.48 3.96 0.48
21 INT16413 Nppa Regulation of Localization of LH 1 0.43 0.76 0.45
22 INT278950 MAPK8 Negative_regulation of Localization of EPHB2 1 0.25 0.47 0.43
23 INT278964 MAPK14 Negative_regulation of Localization of EPHB2 1 0.15 0.47 0.43
24 INT25430 Gtf3a Regulation of Nppa 1 0.24 0.57 0.43
25 INT79486 Nppa Negative_regulation of NA 1 0.03 1.83 0.41
26 INT131356 Binding of Nppa and Npr1 1 0.27 1.73 0.4
27 INT32698 Nppa Regulation of Oxt 1 0.57 0.35 0.35
28 INT32699 Nppa Regulation of Avp 1 0.28 0.35 0.35
29 INT147041 Hmbs Negative_regulation of Negative_regulation of Nppa 1 0.05 0.51 0.3
30 INT30706 Nppa Positive_regulation of Localization of AVP 1 0.78 0.45 0.3
31 INT136245 Gucy1a2 Positive_regulation of Nppa 1 0.06 0.22 0.27
32 INT136246 Gucy1a2 Negative_regulation of Nppa 1 0.05 0.22 0.26
33 INT20587 Nppa Positive_regulation of Gfra1 1 0.02 0.32 0.26
34 INT32636 Slc12a3 Regulation of Localization of Nppa 1 0.00 0.41 0.23
35 INT32565 Nppa Regulation of Localization of CGA 1 0.00 0.07 0.22
36 INT131354 Npr1 Regulation of Nppa 1 0.40 0.88 0.22
37 INT21171 Nppa Regulation of Ren 1 0.35 0.35 0.19
38 INT32700 Nppa Negative_regulation of Oxt 1 0.40 0.16 0.19
39 INT32696 Nppa Negative_regulation of Avp 1 0.45 0.16 0.19
40 INT32697 Nppa Negative_regulation of Gene_expression of Oxt 1 0.40 0.16 0.19
41 INT222025 Gpx3 Regulation of EPHB2 1 0.01 1.41 0.18
42 INT32494 Nppa Negative_regulation of Localization of Avp 1 0.28 1.16 0.18
43 INT172250 Binding of APLNR and CCR1 1 0.12 0 0.17
44 INT222877 Chrm2 Negative_regulation of EPHB2 1 0.05 0.66 0.17
45 INT291354 CXCL12 Positive_regulation of EPHB2 1 0.42 2.02 0.16
46 INT30705 Nppa Negative_regulation of Localization of AVP 1 0.48 0.22 0.15
47 INT172236 Binding of ADM and APLNR 1 0.06 0 0.14
48 INT287890 THEMIS Regulation of Gene_expression of EPHB2 1 0.00 0.87 0.14
49 INT56181 sch Regulation of Positive_regulation of Nppa 1 0.07 0.08 0.14
50 INT287883 FOS Regulation of Gene_expression of EPHB2 1 0.01 0.87 0.14
51 INT326249 Prkcg Positive_regulation of EPHB2 1 0.06 0.63 0.13
52 INT326252 EPHB2 Positive_regulation of ras 1 0.03 0.62 0.13
53 INT291349 CXCR4 Positive_regulation of EPHB2 1 0.42 1.87 0.13
54 INT108330 EGF Negative_regulation of EPHB2 1 0.41 1.15 0.13
55 INT184608 APC Regulation of Gene_expression of Nppa 1 0.06 1.11 0.12
56 INT71755 Nppa Regulation of Localization of Alb 1 0.25 1.29 0.11
57 INT7302 Binding of NPPA and Nppa 1 0.13 1.25 0.11
58 INT42067 Rln1 Positive_regulation of Phosphorylation of Myo1f 1 0.11 0.1 0.1
59 INT5627 Tfpi Positive_regulation of Localization of Nppa 1 0.31 0.07 0.1
60 INT5626 Tfpi Positive_regulation of Transcription of Nppa 1 0.31 0.07 0.1
61 INT224021 PIK3CG Negative_regulation of EPHB2 1 0.03 0.5 0.09
62 INT224020 MAPK1 Negative_regulation of EPHB2 1 0.08 0.56 0.09
63 INT9086 Binding of Nppa and Nppb 1 0.35 0.19 0.08
64 INT27374 Rln1 Regulation of Oxt 1 0.06 0.13 0.07
65 INT42066 Rln1 Regulation of Phosphorylation of Myo1f 1 0.05 0.07 0.07
66 INT51719 Nppa Regulation of Regulation of Pomc 1 0.14 0.1 0.07
67 INT218704 Mapk14 Regulation of EPHB2 1 0.01 0.33 0.05
68 INT16414 Nppa Regulation of Nppb 1 0.24 0.26 0.05
69 INT218703 Mapk8 Regulation of EPHB2 1 0.04 0.33 0.05
70 INT216838 Binding of EPHB2 and Nfkb1 1 0.09 0.15 0.05
71 INT222512 Nppa Positive_regulation of Localization of LH 1 0.02 0 0.05
72 INT66856 Rln1 Positive_regulation of Localization of Mmp2 1 0.30 0 0.05
73 INT218705 Olr811 Regulation of EPHB2 1 0.01 0.32 0.05
74 INT158391 Oxt Positive_regulation of Localization of Nppa 2 0.27 0.64 0.03
75 INT218711 Olr811 Positive_regulation of Phosphorylation of EPHB2 1 0.02 0.33 0.03
76 INT333878 Shc1 Positive_regulation of EPHB2 1 0.08 0.3 0.03
77 INT177671 Vmn1r51 Positive_regulation of Localization of Nppa 1 0.01 0.24 0.03
78 INT14790 Nppa Regulation of Edn3 1 0.45 0.7 0
79 INT293801 EGF Positive_regulation of EPHB2 1 0.11 0 0
80 INT283009 Binding of Bcl2 and Pdss2 1 0.03 0.56 0
81 INT14792 Edn3 Regulation of Nppa 1 0.17 0.17 0
82 INT293819 EPHB2 Positive_regulation of AR 1 0.23 0.12 0
83 INT165146 Kiss1 Regulation of Nppa 1 0.42 0 0
84 INT283004 Binding of Becn1 and Pdss2 1 0.00 0.57 0
85 INT11122 Nppa Negative_regulation of Thop1 1 0.20 0.4 0
86 INT326197 Negative_regulation of HDAC9 Negative_regulation of EPHB2 1 0.17 0.15 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for regulation of body fluid levels. They are ordered first by their pain relevance and then by number of times they were reported in regulation of body fluid levels. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5617 Localization of Nppa 266 0.81 83.51 83.89
2 INT5623 Positive_regulation of Nppa 174 0.70 69.96 52.33
3 INT5620 Positive_regulation of Localization of Nppa 105 0.70 30.23 36.45
4 INT6196 Regulation of Nppa 83 0.62 30.31 30.18
5 INT8205 Negative_regulation of Nppa 77 0.59 26.43 25.72
6 INT5622 Gene_expression of Nppa 101 0.78 49.46 25.31
7 INT5618 Regulation of Localization of Nppa 36 0.62 13.42 17.46
8 INT14764 Negative_regulation of Localization of Nppa 28 0.59 11.29 12.82
9 INT87650 Positive_regulation of EPHB2 49 0.67 22.77 8.25
10 INT108336 Phosphorylation of EPHB2 41 0.80 22.25 8.21
11 INT6210 Binding of Nppa 39 0.47 14.35 7.21
12 INT125143 Gene_expression of EPHB2 40 0.71 13.27 6.97
13 INT6565 Positive_regulation of Positive_regulation of Nppa 14 0.70 4.04 6.76
14 INT5624 Transcription of Nppa 19 0.69 8.52 4.72
15 INT108342 Negative_regulation of EPHB2 18 0.57 9.48 4.46
16 INT5619 Positive_regulation of Gene_expression of Nppa 21 0.70 11.95 4.41
17 INT6193 Regulation of Gene_expression of Nppa 6 0.45 2.02 2.93
18 INT108338 Positive_regulation of Phosphorylation of EPHB2 13 0.67 5.42 2.92
19 INT20498 Negative_regulation of Positive_regulation of Nppa 9 0.59 4.5 2.43
20 INT116077 Positive_regulation of Positive_regulation of EPHB2 4 0.67 2.32 2.13
21 INT25461 Negative_regulation of Regulation of Nppa 2 0.43 0.22 1.97
22 INT11057 Protein_catabolism of Nppa 11 0.94 3.34 1.47
23 INT224501 Positive_regulation of Gene_expression of EPHB2 9 0.49 4.29 1.39
24 INT109924 Localization of EPHB2 6 0.73 2.07 1.28
25 INT108334 Negative_regulation of Phosphorylation of EPHB2 4 0.57 2.27 1.16
26 INT104506 Gene_expression of APLNR 2 0.02 1.19 1.12
27 INT158000 Binding of APLNR 4 0.21 0.2 0.9
28 INT29759 Negative_regulation of Negative_regulation of Nppa 3 0.58 1.5 0.9
29 INT16587 Regulation of Negative_regulation of Nppa 3 0.53 0.84 0.82
30 INT109912 Positive_regulation of Localization of EPHB2 2 0.49 0.56 0.77
31 INT16537 Regulation of Positive_regulation of Nppa 2 0.45 1.44 0.76
32 INT5621 Positive_regulation of Transcription of Nppa 5 0.50 4.97 0.74
33 INT51718 Positive_regulation of Negative_regulation of Nppa 3 0.47 0.79 0.57
34 INT7293 Negative_regulation of Binding of Nppa 5 0.43 1.4 0.55
35 INT288644 Binding of Pdss2 2 0.25 1.37 0.55
36 INT278982 Regulation of EPHB2 6 0.44 1.97 0.53
37 INT125139 Regulation of Gene_expression of EPHB2 3 0.44 1.07 0.52
38 INT224498 Regulation of Positive_regulation of EPHB2 1 0.26 0.46 0.52
39 INT120403 Regulation of Phosphorylation of EPHB2 2 0.60 1.92 0.5
40 INT5625 Regulation of Transcription of Nppa 2 0.26 0.29 0.46
41 INT9697 Positive_regulation of Rln1 2 0.49 0.31 0.43
42 INT6563 Positive_regulation of Regulation of Nppa 1 0.33 0.44 0.41
43 INT38562 Localization of Rln1 2 0.73 0 0.4
44 INT32533 Negative_regulation of Gene_expression of Nppa 2 0.32 1.93 0.38
45 INT278976 Negative_regulation of Gene_expression of EPHB2 1 0.41 0.51 0.32
46 INT17158 Regulation of Protein_catabolism of Nppa 1 0.24 0.1 0.28
47 INT109932 Protein_catabolism of EPHB2 3 0.86 0.14 0.24
48 INT109923 Positive_regulation of Protein_catabolism of EPHB2 1 0.49 0.14 0.24
49 INT27373 Negative_regulation of Rln1 2 0.58 0.24 0.2
50 INT84554 Regulation of Regulation of Nppa 1 0.27 0.39 0.18
51 INT11058 Positive_regulation of Protein_catabolism of Nppa 1 0.37 0.53 0.17
52 INT42061 Phosphorylation of Rln1 1 0.25 0.07 0.07
53 INT66855 Regulation of Rln1 1 0.09 0 0.07
54 INT185622 Localization of APLNR 1 0.01 0.21 0.04
55 INT235653 Binding of EPHB2 1 0.08 1.04 0
56 INT326230 Regulation of Negative_regulation of EPHB2 1 0.44 0 0
57 INT326234 Regulation of Protein_catabolism of EPHB2 1 0.44 0 0
58 INT326236 Negative_regulation of Negative_regulation of EPHB2 1 0.41 0 0
59 INT266536 Negative_regulation of Protein_catabolism of EPHB2 1 0.41 0 0
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