GO:0050883

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Name musculoskeletal movement, spinal reflex action
Categary Process
Go Slim No
Go Link GO:0050883
Unique Molecular Interactions 67
Total Molecular Interactions 94
Total Single Events 701
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for musculoskeletal movement, spinal reflex action. They are ordered first by their pain relevance and then by number of times they were reported for musculoskeletal movement, spinal reflex action. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT140347 Binding of ATP1A2 and Cacna1a 1 0.11 2.88 2.73
2 INT74840 Binding of Cacna1a and Cacna1a 5 0.00 4.24 2.36
3 INT122660 Binding of CACNA1A and DNAH8 2 0.28 2.68 2.08
4 INT355251 Cacna1a Regulation of Gene_expression of Gabrg1 1 0.01 0.06 1.86
5 INT355249 Cacna1a Regulation of Gene_expression of Ltp 1 0.04 0.06 1.86
6 INT355254 Ltp Regulation of Cacna1a 1 0.04 0 1.58
7 INT74843 Binding of Cacna1a and Ea2 3 0.13 3.29 1.55
8 INT355250 Ltp Regulation of Positive_regulation of Cacna1a 1 0.04 0 1.39
9 INT108727 Binding of ATP1A2 and CACNA1A 2 0.34 1.97 1.37
10 INT122659 Binding of CACNA1A and SAR1B 1 0.06 1.38 1.35
11 INT355253 Ltp Positive_regulation of Cacna1a 1 0.05 0 1.34
12 INT355252 Binding of Cacna1a and Cnr1 1 0.04 0 1.31
13 INT74841 Binding of Cacna1a and Ea2 2 0.01 2.33 1.27
14 INT108729 Binding of CACNA1A and Cacna1a 3 0.13 1.21 0.95
15 INT214410 Binding of ATP1A4 and CACNA1A 1 0.26 0.95 0.7
16 INT31416 Cacna1a Positive_regulation of Gene_expression of Gcg 1 0.03 0 0.65
17 INT127056 Ddc Positive_regulation of Transcription of Drd3 1 0.10 0.06 0.63
18 INT354986 Cacna1a Regulation of Localization of Mpo 1 0.01 1.15 0.49
19 INT354981 Cacna1a Negative_regulation of Gene_expression of Nos2 1 0.01 0.99 0.45
20 INT155752 Binding of CACNA1A and ATCAY 1 0.04 0.86 0.42
21 INT191610 Binding of App and Drd3 1 0.20 0.7 0.42
22 INT354984 Binding of Cacna1a and Tnf 1 0.01 0.83 0.4
23 INT81506 Drd3 Regulation of Positive_regulation of Fos 1 0.28 0 0.37
24 INT158355 Cacna1a Regulation of Alox5 1 0.01 0.7 0.37
25 INT138515 Drd3 Negative_regulation of Localization of Tnf 1 0.06 0.4 0.36
26 INT354985 Cacna1a Regulation of Nos2 1 0.01 0.73 0.34
27 INT354982 Cacna1a Regulation of Tnf 1 0.00 0.73 0.34
28 INT51629 Binding of DRD3 and OPRK1 1 0.15 0 0.33
29 INT51628 Binding of ACHE and DRD3 1 0.15 0 0.33
30 INT101551 Binding of CACNA1A and CACNA1F 1 0.07 1.51 0.33
31 INT51631 Binding of DRD3 and PENK 1 0.08 0 0.33
32 INT151258 Binding of Cacna1a and FCMTE1 1 0.00 0.57 0.3
33 INT142003 Binding of Cacna1a and Etax2 1 0.00 1.02 0.26
34 INT105004 Binding of DRD3 and PDYN 1 0.23 0.49 0.26
35 INT142004 Binding of Cacna1a and TGM6 1 0.00 1.02 0.26
36 INT46400 Negative_regulation of Drd3 Positive_regulation of Localization of Prl 1 0.15 0.09 0.22
37 INT46399 Negative_regulation of Drd3 Positive_regulation of Prl 1 0.15 0.09 0.22
38 INT148345 Binding of Drd3 and Adra1a 1 0.18 0.12 0.21
39 INT121807 CACNA1A Regulation of CAV2 1 0.01 0.25 0.2
40 INT191609 Binding of Drd3 and Flna 1 0.06 0.42 0.17
41 INT191621 Binding of Drd3 and Nf1 1 0.32 0.53 0.17
42 INT157097 Ddc Positive_regulation of Drd3 1 0.30 0.88 0.16
43 INT71329 Cacna1a Regulation of Ea2 1 0.01 0.71 0.15
44 INT71328 Cacna1a Regulation of Atxn2 1 0.00 0.71 0.15
45 INT120559 Binding of Cacna1a and FCMTE1 1 0.02 0.25 0.1
46 INT196213 REST Regulation of Gene_expression of CACNA1A 1 0.46 0.08 0.08
47 INT354983 Cacna1a Regulation of Mpo 1 0.02 0.41 0.04
48 INT354987 Cacna1a Regulation of Localization of LDHA 1 0.00 0.23 0.03
49 INT196208 REST Regulation of CACNA1A 1 0.46 0.06 0
50 INT196216 Binding of CACNA1A and REST 1 0.28 0 0
51 INT261963 Binding of Cacna1a and Tgm2 1 0.08 1.19 0
52 INT250496 Gopc Regulation of Positive_regulation of Cacna1a 1 0.37 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for musculoskeletal movement, spinal reflex action. They are ordered first by their pain relevance and then by number of times they were reported in musculoskeletal movement, spinal reflex action. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT66331 Gene_expression of Cacna1a 101 0.78 49.58 46.32
2 INT26698 Positive_regulation of Cacna1a 37 0.67 26.33 39.1
3 INT41487 Negative_regulation of Cacna1a 16 0.57 9.42 25.2
4 INT31136 Binding of Cacna1a 28 0.45 30.76 17.35
5 INT30101 Regulation of Cacna1a 25 0.45 14.38 12.43
6 INT75765 Positive_regulation of Gene_expression of Cacna1a 17 0.70 17.51 10.91
7 INT75955 Gene_expression of Drd3 19 0.77 4.39 10.07
8 INT68267 Gene_expression of CACNA1A 22 0.75 11.39 8.65
9 INT64215 Gene_expression of Drd3 16 0.78 5.27 6.71
10 INT91821 Binding of Cacna1a 16 0.48 13.1 6.37
11 INT42799 Positive_regulation of Drd3 11 0.69 1.1 5.92
12 INT129508 Localization of Cacna1a 7 0.74 6.47 5.13
13 INT50330 Positive_regulation of Drd3 7 0.70 0.76 5.08
14 INT110796 Positive_regulation of Positive_regulation of Cacna1a 1 0.49 0.51 4.84
15 INT24011 Binding of Drd3 13 0.47 3.03 4.64
16 INT82731 Transcription of Cacna1a 5 0.56 3.41 4.27
17 INT76714 Binding of Drd3 9 0.37 2.33 4.09
18 INT287526 Negative_regulation of Gene_expression of CACNA1A 1 0.42 4.25 3.81
19 INT89329 Regulation of Gene_expression of Drd3 4 0.61 0.72 3.56
20 INT53516 Binding of CACNA1A 9 0.47 6.86 3.36
21 INT94045 Regulation of Cacna1a 5 0.42 3.56 3.33
22 INT78317 Regulation of CACNA1A 8 0.62 7.68 3.08
23 INT85572 Gene_expression of Cacna1a 11 0.66 5.72 3.02
24 INT142940 Positive_regulation of Negative_regulation of Cacna1a 3 0.50 1.65 2.97
25 INT82992 Gene_expression of DRD3 3 0.50 2.12 2.88
26 INT99419 Regulation of Drd3 7 0.48 1.89 2.81
27 INT355244 Negative_regulation of Negative_regulation of Cacna1a 1 0.04 0 2.67
28 INT89327 Positive_regulation of Gene_expression of Drd3 4 0.54 0.32 2.64
29 INT89326 Transcription of Drd3 4 0.37 0.67 2.58
30 INT161575 Localization of CACNA1A 4 0.75 5.28 2.26
31 INT51047 Regulation of Drd3 4 0.53 2 2.2
32 INT110795 Regulation of Positive_regulation of Cacna1a 2 0.26 0.65 2.07
33 INT105008 Binding of DRD3 5 0.36 3.15 2.05
34 INT89330 Positive_regulation of Binding of Drd3 1 0.31 0.16 1.81
35 INT354979 Positive_regulation of Localization of Cacna1a 2 0.05 0.86 1.79
36 INT355239 Negative_regulation of Positive_regulation of Cacna1a 1 0.04 0 1.79
37 INT71327 Localization of Cacna1a 3 0.60 2.51 1.7
38 INT267108 Negative_regulation of Gene_expression of DRD3 2 0.26 1.53 1.69
39 INT355242 Negative_regulation of Binding of Cacna1a 1 0.04 0.17 1.47
40 INT355245 Regulation of Localization of Cacna1a 1 0.04 0 1.43
41 INT90740 Negative_regulation of Cacna1a 3 0.23 1.43 1.38
42 INT112063 Regulation of Gene_expression of Drd3 2 0.09 1.84 1.31
43 INT82991 Regulation of Gene_expression of DRD3 1 0.23 0.59 1.26
44 INT82988 Regulation of Transcription of DRD3 1 0.38 0.59 1.26
45 INT82987 Transcription of DRD3 1 0.58 0.59 1.25
46 INT82727 Positive_regulation of Transcription of Cacna1a 1 0.01 1.07 1.25
47 INT89328 Regulation of Transcription of Drd3 2 0.22 0.51 1.21
48 INT4570 Negative_regulation of Drd3 4 0.39 0.09 1.2
49 INT85571 Positive_regulation of Cacna1a 3 0.50 2.06 1.18
50 INT355243 Negative_regulation of Regulation of Cacna1a 1 0.04 0 1.16
51 INT60441 Positive_regulation of Positive_regulation of Drd3 1 0.21 0 1.07
52 INT88083 Negative_regulation of Drd3 3 0.58 0.88 1.01
53 INT127052 Transcription of Drd3 2 0.37 0.06 1
54 INT82989 Regulation of DRD3 1 0.23 0.45 0.99
55 INT321650 Negative_regulation of Gene_expression of Cacna1a 2 0.04 0.13 0.95
56 INT94046 Protein_catabolism of Cacna1a 1 0.70 0.83 0.9
57 INT131964 Positive_regulation of CACNA1A 5 0.61 0.73 0.85
58 INT89331 Positive_regulation of Transcription of Drd3 1 0.21 0.09 0.85
59 INT119491 Positive_regulation of Positive_regulation of Drd3 1 0.46 0.17 0.83
60 INT103336 Transcription of Cacna1a 2 0.69 1.17 0.68
61 INT141227 Phosphorylation of CACNA1A 1 0.55 0.78 0.66
62 INT127050 Positive_regulation of Transcription of Drd3 1 0.26 0.06 0.62
63 INT189813 Negative_regulation of CACNA1A 4 0.57 3.07 0.55
64 INT122930 Positive_regulation of Gene_expression of CACNA1A 2 0.49 0.91 0.54
65 INT89285 Positive_regulation of Gene_expression of Drd3 2 0.60 0.09 0.52
66 INT119492 Positive_regulation of Negative_regulation of Drd3 1 0.69 0.07 0.43
67 INT124636 Negative_regulation of Positive_regulation of Drd3 1 0.43 0.09 0.41
68 INT124635 Localization of Drd3 1 0.75 0.08 0.39
69 INT317624 Regulation of Phosphorylation of Drd3 1 0.05 0.46 0.36
70 INT317616 Phosphorylation of Drd3 1 0.12 0.46 0.36
71 INT261442 Negative_regulation of Gene_expression of Drd3 1 0.04 0.7 0.35
72 INT99962 Positive_regulation of Gene_expression of Cacna1a 1 0.01 1.1 0.34
73 INT155753 Regulation of Gene_expression of CACNA1A 1 0.27 0.66 0.32
74 INT105005 Positive_regulation of Positive_regulation of DRD3 1 0.48 0.5 0.28
75 INT105006 Positive_regulation of DRD3 1 0.48 0.5 0.27
76 INT24010 Negative_regulation of Binding of Drd3 1 0.39 0 0.27
77 INT89286 Positive_regulation of Binding of Drd3 1 0.69 0 0.23
78 INT89284 Regulation of Binding of Drd3 1 0.45 0 0.2
79 INT344112 Regulation of Transcription of Drd3 1 0.04 0 0.2
80 INT196235 Negative_regulation of Transcription of CACNA1A 1 0.36 0.1 0.07
81 INT196229 Transcription of CACNA1A 1 0.60 0.24 0.07
82 INT309389 Phosphorylation of Cacna1a 1 0.01 0.54 0.05
83 INT309386 Positive_regulation of Phosphorylation of Cacna1a 1 0.01 0.54 0.05
84 INT196237 Positive_regulation of Transcription of CACNA1A 1 0.39 0.14 0
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