GO:0050891

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Name multicellular organismal water homeostasis
Categary Process
Go Slim No
Go Link GO:0050891
Unique Molecular Interactions 337
Total Molecular Interactions 535
Total Single Events 6762
Pain Genes Associated 8

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for multicellular organismal water homeostasis. They are ordered first by their pain relevance and then by number of times they were reported for multicellular organismal water homeostasis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT140015 Avp Positive_regulation of Localization of Penk 3 0.63 3.48 6.63
2 INT38217 Penk Regulation of Localization of Avp 2 0.38 0.56 4.45
3 INT161109 Avp Positive_regulation of Chkb 1 0.12 0.18 4.19
4 INT15984 Binding of Avp and Oxt 11 0.32 1.33 3.64
5 INT140011 Avp Positive_regulation of Dbi 2 0.07 0.93 3.61
6 INT140014 Avp Negative_regulation of Chkb 1 0.04 1.58 2.86
7 INT206764 Binding of AQP4 and Nqo1 8 0.05 13.45 2.84
8 INT7888 Oprl1 Regulation of Localization of Avp 4 0.49 0.25 2.63
9 INT107812 Nppa Positive_regulation of Localization of Sst 1 0.48 0.54 2.51
10 INT66803 Oxt Regulation of Avp 7 0.16 0.19 2.15
11 INT140019 Avp Positive_regulation of Localization of Kitl 1 0.00 1 2.13
12 INT138960 Dbi Positive_regulation of Avp 1 0.02 1.53 2
13 INT138958 Dbi Positive_regulation of Positive_regulation of Avp 1 0.02 1.53 2
14 INT45423 Avp Positive_regulation of Localization of Prl 4 0.67 1.37 1.98
15 INT149470 Oxt Regulation of Gene_expression of Avp 1 0.46 1.2 1.92
16 INT40239 Penk Regulation of Avp 1 0.07 0 1.84
17 INT117269 Binding of Avp and Prl 1 0.25 0.47 1.8
18 INT10202 Agt Positive_regulation of Avp 3 0.70 0 1.69
19 INT144213 Nppa Positive_regulation of Localization of Calca 1 0.71 2.8 1.65
20 INT140009 Avp Positive_regulation of Gene_expression of Penk 1 0.40 0.77 1.64
21 INT140023 Avp Positive_regulation of Gene_expression of Kitl 1 0.00 0.76 1.62
22 INT107815 Gene_expression of Sst Positive_regulation of Localization of Nppa 1 0.52 0.27 1.57
23 INT94271 Pomc Regulation of Avp 1 0.20 0.67 1.57
24 INT130838 Gfap Positive_regulation of Aqp4 1 0.51 1.9 1.56
25 INT140013 Avp Positive_regulation of Gene_expression of Dbi 1 0.07 0.85 1.52
26 INT140016 Avp Positive_regulation of Gene_expression of Pdyn 1 0.21 0.85 1.52
27 INT140017 Avp Positive_regulation of Gene_expression of Pomc 1 0.38 0.85 1.52
28 INT140008 Avp Positive_regulation of Pomc 1 0.38 0.84 1.51
29 INT59547 Avp Positive_regulation of Crh 2 0.14 1.13 1.47
30 INT107813 Sst Negative_regulation of Localization of Nppa 1 0.44 0.2 1.46
31 INT45307 ENG Positive_regulation of Localization of Avp 1 0.00 0 1.45
32 INT140012 Avp Negative_regulation of Dbi 1 0.06 0.8 1.44
33 INT5534 Binding of Oxt and Avp 7 0.04 0.6 1.43
34 INT142490 Avp Regulation of Oxt 1 0.09 0.74 1.4
35 INT140021 Avp Positive_regulation of Pag1 1 0.03 0.85 1.38
36 INT140018 Avp Positive_regulation of Gene_expression of Pag1 1 0.04 0.85 1.38
37 INT140020 Avp Positive_regulation of Localization of Pag1 1 0.03 0.85 1.38
38 INT31772 Ednra Positive_regulation of Nppa 1 0.05 0.13 1.33
39 INT31771 Penk Positive_regulation of Nppa 1 0.22 0.13 1.28
40 INT31773 Pdyn Positive_regulation of Nppa 1 0.12 0.13 1.27
41 INT62596 Binding of Edn1 and Nppa 1 0.27 1.77 1.22
42 INT140010 Avp Regulation of Gene_expression of Penk 1 0.25 0.58 1.19
43 INT75126 Pnoc Regulation of Localization of Avp 2 0.26 0.24 1.18
44 INT27621 Avp Positive_regulation of Protein_catabolism of Mbis1 1 0.00 0 1.18
45 INT140022 Avp Regulation of Localization of Pag1 1 0.01 0.57 1.17
46 INT43509 Avp Positive_regulation of Localization of POMC 2 0.13 1.26 1.16
47 INT164722 Avp Regulation of NT5C 1 0.06 0.88 1.15
48 INT94490 Il6 Positive_regulation of Gene_expression of Avp 1 0.33 1.97 1.15
49 INT94502 Il1b Positive_regulation of Gene_expression of Avp 1 0.28 1.97 1.15
50 INT94509 Il1b Positive_regulation of Gene_expression of AVP 1 0.36 1.96 1.15
51 INT94508 Il6 Positive_regulation of Gene_expression of AVP 1 0.42 1.96 1.14
52 INT2457 Agt Positive_regulation of Localization of Avp 5 0.59 0.2 1.09
53 INT250253 Binding of AQP4 and SLC1A2 1 0.30 2.95 1.09
54 INT38936 Binding of Avp and Crh 7 0.40 0.82 1.04
55 INT63103 AVP Regulation of OXT 1 0.28 0.68 1.02
56 INT85320 Binding of Avp and Vas1 1 0.00 0.87 0.98
57 INT94493 Avp Positive_regulation of Gene_expression of Ifng 1 0.05 1.73 0.97
58 INT149471 Avp Regulation of Gene_expression of Crh 1 0.45 0.6 0.96
59 INT149474 Avp Regulation of Gene_expression of Oxt 1 0.27 0.6 0.96
60 INT43454 Pomc Regulation of Localization of Avp 2 0.24 0.89 0.94
61 INT51542 Negative_regulation of Binding of Avp and Penk 1 0.46 0.05 0.94
62 INT51541 Positive_regulation of Binding of Avp and Penk 1 0.74 0.05 0.94
63 INT51545 Binding of Avp and Penk 1 0.51 0.05 0.94
64 INT64127 Igfbp2 Regulation of Localization of Avp 1 0.39 0.19 0.9
65 INT121467 Binding of Avp and Ptafr 1 0.11 0.98 0.88
66 INT26529 Prl Regulation of Avp 1 0.08 0.26 0.85
67 INT41863 Avp Regulation of Cck 1 0.00 0 0.84
68 INT41865 Avp Regulation of Cpe 1 0.00 0 0.84
69 INT41857 Avp Regulation of Vip 1 0.01 0 0.84
70 INT19299 ANG Regulation of AVP 1 0.25 0 0.82
71 INT16436 Ubqln1 Regulation of Localization of Avp 1 0.01 0 0.81
72 INT16439 Atp6v0d2 Regulation of Localization of Avp 1 0.02 0 0.81
73 INT47143 Negative_regulation of Agt Positive_regulation of Avp 1 0.22 0 0.79
74 INT9527 Avp Positive_regulation of Localization of Pomc 7 0.58 0.29 0.77
75 INT250248 Binding of AQP4 and SLC1A3 1 0.11 1.55 0.77
76 INT107810 Sst Positive_regulation of Localization of Nppa 1 0.42 0.14 0.77
77 INT147251 Binding of Avp and Gal 1 0.15 0.19 0.76
78 INT12396 Binding of Avp and IGKV1-5 3 0.04 1.38 0.75
79 INT334153 Binding of AQP4 and CSF2 1 0.16 3 0.75
80 INT45305 Pomc Positive_regulation of Localization of Avp 1 0.12 0 0.73
81 INT164713 Binding of Avp and Positive_regulation of Localization of Acot1 1 0.32 0.43 0.69
82 INT164715 Avp Positive_regulation of Localization of Acot1 1 0.28 0.43 0.69
83 INT48032 Binding of Avp and Pebp1 1 0.00 0 0.68
84 INT11611 Cck Positive_regulation of Localization of Avp 1 0.09 0 0.67
85 INT11612 Cck Positive_regulation of Avp 1 0.10 0 0.67
86 INT164723 Binding of Avp and NT5C 1 0.07 0.45 0.65
87 INT164714 Binding of Avp and Acot1 1 0.26 0.45 0.64
88 INT48033 Binding of Avp and LH 1 0.08 0 0.64
89 INT16412 Nppa Negative_regulation of Localization of LH 2 0.41 0.29 0.62
90 INT25957 Gabrg1 Regulation of Localization of AVP 1 0.01 0 0.62
91 INT250247 FCGR3A Negative_regulation of AQP4 1 0.01 0.87 0.62
92 INT32747 Avp Positive_regulation of Localization of Pomc 4 0.16 1.92 0.61
93 INT27067 Crh Positive_regulation of Localization of Avp 3 0.18 0.46 0.61
94 INT37555 FDX1 Positive_regulation of Regulation of Avp 1 0.04 0 0.61
95 INT42269 POMC Negative_regulation of Localization of AVP 1 0.09 0 0.61
96 INT147049 CB Positive_regulation of Nppa 1 0.02 1.01 0.6
97 INT352496 AVP Regulation of Gene_expression of CRS 1 0.27 2.47 0.59
98 INT29847 INS Regulation of Localization of AVP 1 0.23 0.24 0.59
99 INT109803 Binding of Avp and Oprl1 1 0.07 0.1 0.59
100 INT64036 Binding of AVP and HTR1A 1 0.40 0.36 0.57
101 INT94506 Tnf Positive_regulation of Gene_expression of Avp 1 0.31 0.98 0.57
102 INT94507 Tnf Positive_regulation of Gene_expression of AVP 1 0.39 0.98 0.57
103 INT101216 Pnoc Positive_regulation of Localization of Nppa 1 0.68 0.09 0.57
104 INT149473 Avp Positive_regulation of Localization of Pomc 4 0.48 2.64 0.56
105 INT169648 IGHG3 Regulation of AQP4 3 0.02 4.63 0.55
106 INT147040 Hmbs Negative_regulation of Nppa 1 0.07 0.95 0.55
107 INT107814 Nppa Positive_regulation of Positive_regulation of Sst 1 0.42 0.16 0.55
108 INT16643 Nppa Regulation of Rabep2 1 0.13 0.07 0.55
109 INT255463 Binding of Avp and Avpr1a 1 0.06 0.67 0.54
110 INT75129 Pnoc Negative_regulation of Avp 1 0.13 0 0.54
111 INT129869 SERPINA6 Regulation of AVP 1 0.25 2.33 0.54
112 INT235975 Binding of AQP4 and IgG 2 0.04 4.11 0.53
113 INT235956 Binding of Aqp4 and NMO-IgG 1 0.04 4.53 0.5
114 INT19296 AGT Positive_regulation of Localization of AVP 1 0.38 0 0.5
115 INT55553 Avp Regulation of Serpina6 1 0.02 0 0.49
116 INT161166 Binding of Aqp4 and Igh-6 1 0.03 2.58 0.49
117 INT47141 Creg2-ps1 Positive_regulation of Avp 1 0.01 0 0.48
118 INT47142 Negative_regulation of Creg2-ps1 Positive_regulation of Avp 1 0.01 0 0.48
119 INT66801 Oxt Regulation of Localization of Avp 1 0.08 0 0.48
120 INT61848 Npff Regulation of Localization of Avp 1 0.26 0.3 0.48
121 INT280826 Il6 Positive_regulation of Localization of Avp 1 0.01 0.64 0.47
122 INT59546 Avp Positive_regulation of Localization of Crh 1 0.05 0.08 0.47
123 INT16677 Binding of Avp and Oprd1 1 0.02 0.8 0.47
124 INT59548 Negative_regulation of Avp Positive_regulation of Crh 1 0.04 0.08 0.47
125 INT19297 ANG Positive_regulation of AVP 1 0.28 0 0.46
126 INT175788 Il2 Positive_regulation of Localization of Avp 1 0.03 0.41 0.46
127 INT27065 Kndc1 Positive_regulation of Localization of Avp 1 0.00 0 0.46
128 INT16413 Nppa Regulation of Localization of LH 1 0.43 0.76 0.45
129 INT43453 Pomc Negative_regulation of Localization of Avp 1 0.38 0.82 0.45
130 INT157343 Binding of AQP4 and HLA-DPB1 1 0.30 0.89 0.43
131 INT36459 Binding of Agt and Positive_regulation of Localization of Avp 1 0.38 0.19 0.43
132 INT25430 Gtf3a Regulation of Nppa 1 0.24 0.57 0.43
133 INT69173 Avp Positive_regulation of Oxt 1 0.18 0 0.42
134 INT126979 Penk Negative_regulation of Localization of AVP 1 0.00 0 0.41
135 INT79486 Nppa Negative_regulation of NA 1 0.03 1.83 0.41
136 INT126975 Penk Negative_regulation of Localization of Avp 1 0.00 0 0.41
137 INT36460 Binding of Agt and Avp 1 0.28 0.16 0.4
138 INT131356 Binding of Nppa and Npr1 1 0.27 1.73 0.4
139 INT7634 RFC1 Negative_regulation of Localization of AVP 1 0.46 0 0.39
140 INT250250 Gene_expression of AQP4 Positive_regulation of Gene_expression of SLC1A2 1 0.37 1.1 0.39
141 INT40395 Ins1 Positive_regulation of Localization of Avp 1 0.16 0.09 0.38
142 INT354062 Avp Regulation of Lyz2 1 0.00 0.12 0.38
143 INT84602 Binding of Adrb1 and Avp 1 0.00 0 0.36
144 INT241780 Binding of AVP and TRGV9 1 0.12 2.41 0.35
145 INT250242 Binding of AQP4 and GOPC 1 0.06 0.39 0.35
146 INT32698 Nppa Regulation of Oxt 1 0.57 0.35 0.35
147 INT32699 Nppa Regulation of Avp 1 0.28 0.35 0.35
148 INT84600 Binding of Avp and Aqp2 1 0.17 0 0.35
149 INT37552 Crh Regulation of Avp 1 0.22 0 0.34
150 INT37551 Positive_regulation of Crh Regulation of Avp 1 0.38 0 0.34
151 INT37554 Avp Regulation of FDX1 1 0.01 0 0.34
152 INT241776 Binding of AVP and Positive_regulation of ADCY1 1 0.06 0.54 0.32
153 INT308701 Binding of AQP4 and DDX41 1 0.15 3.53 0.32
154 INT115597 Avp Positive_regulation of Crh 1 0.56 0.79 0.31
155 INT66908 Il1b Positive_regulation of Localization of Avp 1 0.36 0.49 0.31
156 INT31275 Avp Negative_regulation of Cpe 1 0.00 0 0.31
157 INT147041 Hmbs Negative_regulation of Negative_regulation of Nppa 1 0.05 0.51 0.3
158 INT12390 AVP Regulation of Localization of POMC 1 0.29 0.27 0.3
159 INT15263 Gal Regulation of Localization of Avp 1 0.67 0 0.3
160 INT30706 Nppa Positive_regulation of Localization of AVP 1 0.78 0.45 0.3
161 INT139778 Binding of AQP1 and GBE1 1 0.00 0.22 0.3
162 INT235958 Binding of Ighg1 and Aqp4 1 0.14 1.32 0.3
163 INT235977 Binding of AQP4 and Ighg1 1 0.03 1.31 0.3
164 INT89909 AVP Positive_regulation of Localization of POMC 1 0.44 0 0.29
165 INT89906 AVP Positive_regulation of Localization of GH1 1 0.14 0 0.29
166 INT89903 AVP Positive_regulation of Localization of PRL 1 0.40 0 0.29
167 INT45543 Ncapg2 Regulation of Localization of Avp 1 0.00 0 0.28
168 INT83410 Oxt Positive_regulation of Avp 1 0.20 0.35 0.28
169 INT280827 Positive_regulation of Fos Positive_regulation of Avp 1 0.02 0.08 0.28
170 INT280825 Mapk1 Positive_regulation of Avp 1 0.01 0.08 0.28
171 INT102923 Ptgds Regulation of Avp 1 0.02 0 0.27
172 INT72820 EDN3 Positive_regulation of Avp 1 0.31 0.64 0.27
173 INT136245 Gucy1a2 Positive_regulation of Nppa 1 0.06 0.22 0.27
174 INT293118 Avp Regulation of Aqp2 1 0.04 0.7 0.27
175 INT280805 Positive_regulation of Prkcg Positive_regulation of Avp 1 0.01 0.16 0.26
176 INT308708 DDX41 Regulation of AQP4 1 0.10 2.79 0.26
177 INT235959 Nqo1 Positive_regulation of Localization of Aqp4 1 0.02 1.39 0.26
178 INT136246 Gucy1a2 Negative_regulation of Nppa 1 0.05 0.22 0.26
179 INT20587 Nppa Positive_regulation of Gfra1 1 0.02 0.32 0.26
180 INT74118 Adcyap1 Positive_regulation of Localization of Avp 1 0.33 0 0.26
181 INT32636 Slc12a3 Regulation of Localization of Nppa 1 0.00 0.41 0.23
182 INT58305 AQP1 Regulation of Localization of TNF 1 0.10 0.16 0.22
183 INT58303 AQP1 Regulation of Gene_expression of IL1B 1 0.10 0.16 0.22
184 INT354544 Avp Positive_regulation of ADCY1 1 0.24 2.23 0.22
185 INT32565 Nppa Regulation of Localization of CGA 1 0.00 0.07 0.22
186 INT87061 Binding of AVP and IL6 1 0.26 1.04 0.22
187 INT131354 Npr1 Regulation of Nppa 1 0.40 0.88 0.22
188 INT149468 Avp Positive_regulation of Localization of Mc2r 1 0.07 0.26 0.21
189 INT52629 Binding of AVP and NMS 1 0.04 1.04 0.21
190 INT64334 Avp Regulation of POMC 1 0.06 0.14 0.21
191 INT25720 Npy Negative_regulation of Avp 1 0.48 0.1 0.21
192 INT25721 Negative_regulation of Npy Negative_regulation of Avp 1 0.48 0.1 0.21
193 INT33559 Binding of POMC and Avp 1 0.11 0.22 0.2
194 INT3592 INS Positive_regulation of AVP 1 0.05 0.28 0.2
195 INT3591 Negative_regulation of INS Positive_regulation of AVP 1 0.04 0.28 0.2
196 INT45424 Avp Positive_regulation of Regulation of Prl 1 0.34 0 0.19
197 INT25951 Ins1 Regulation of Avp 1 0.16 0.15 0.19
198 INT21171 Nppa Regulation of Ren 1 0.35 0.35 0.19
199 INT139358 Tac1 Regulation of Avp 1 0.41 0.08 0.19
200 INT25495 AVP Positive_regulation of CRH 1 0.14 0 0.19

Single Events

The table below shows the top 100 pain related interactions that have been reported for multicellular organismal water homeostasis. They are ordered first by their pain relevance and then by number of times they were reported in multicellular organismal water homeostasis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT477 Localization of Avp 813 0.81 131.58 300.4
2 INT2451 Positive_regulation of Avp 355 0.70 102.66 147.69
3 INT1273 Gene_expression of Avp 356 0.78 90.56 138.7
4 INT4207 Regulation of Avp 267 0.62 63.72 115.33
5 INT5940 Negative_regulation of Avp 236 0.59 67.86 101.2
6 INT214 Localization of AVP 370 0.81 208.51 91.09
7 INT5617 Localization of Nppa 266 0.81 83.51 83.89
8 INT4358 Positive_regulation of Localization of Avp 195 0.70 30.79 77.58
9 INT7886 Regulation of Localization of Avp 146 0.62 14.53 72.99
10 INT480 Negative_regulation of Localization of Avp 151 0.59 27.64 63.72
11 INT5623 Positive_regulation of Nppa 174 0.70 69.96 52.33
12 INT683 Positive_regulation of AVP 173 0.70 74.55 46.41
13 INT685 Regulation of AVP 124 0.62 34.9 39.91
14 INT5620 Positive_regulation of Localization of Nppa 105 0.70 30.23 36.45
15 INT3679 Gene_expression of AVP 171 0.78 72.9 35.23
16 INT6196 Regulation of Nppa 83 0.62 30.31 30.18
17 INT130837 Gene_expression of Aqp4 205 0.78 151.23 29.63
18 INT894 Binding of Avp 84 0.48 29.16 29.63
19 INT8205 Negative_regulation of Nppa 77 0.59 26.43 25.72
20 INT140413 Gene_expression of AQP4 113 0.78 139.25 25.53
21 INT5622 Gene_expression of Nppa 101 0.78 49.46 25.31
22 INT682 Negative_regulation of AVP 97 0.59 50.67 23.91
23 INT11303 Gene_expression of Avp 116 0.78 39.23 23.88
24 INT6127 Regulation of Localization of AVP 60 0.62 15.12 20.84
25 INT7470 Positive_regulation of Gene_expression of Avp 37 0.70 19.55 19.96
26 INT5499 Transcription of Avp 52 0.72 7.98 19.87
27 INT5618 Regulation of Localization of Nppa 36 0.62 13.42 17.46
28 INT213 Negative_regulation of Localization of AVP 46 0.59 19.78 16.79
29 INT6129 Positive_regulation of Localization of AVP 63 0.70 30.44 16.64
30 INT14764 Negative_regulation of Localization of Nppa 28 0.59 11.29 12.82
31 INT11141 Negative_regulation of Gene_expression of Avp 23 0.59 3.85 12.19
32 INT13743 Regulation of Gene_expression of Avp 30 0.62 6.9 11.66
33 INT15262 Negative_regulation of Positive_regulation of Avp 22 0.58 3.28 10.81
34 INT250282 Negative_regulation of AQP4 32 0.54 32.96 9.07
35 INT684 Binding of AVP 38 0.48 13.9 8.85
36 INT10879 Positive_regulation of Avp 39 0.65 14.01 8.76
37 INT44550 Positive_regulation of Gene_expression of AVP 38 0.70 22.27 8.62
38 INT13739 Positive_regulation of Positive_regulation of Avp 18 0.70 4.78 8.2
39 INT157959 Binding of AQP4 32 0.48 43.44 7.44
40 INT136304 Negative_regulation of Aqp4 54 0.59 48.42 7.4
41 INT6210 Binding of Nppa 39 0.47 14.35 7.21
42 INT19806 Regulation of Avp 29 0.53 14.17 6.94
43 INT6565 Positive_regulation of Positive_regulation of Nppa 14 0.70 4.04 6.76
44 INT66811 Positive_regulation of Transcription of Avp 11 0.70 2.1 6.46
45 INT40962 Localization of Avp 40 0.80 20.5 6.38
46 INT7138 Regulation of Regulation of Avp 10 0.36 1.99 6.37
47 INT19805 Negative_regulation of Avp 18 0.59 4.57 5.87
48 INT21380 Regulation of Transcription of Avp 10 0.62 2.6 5.46
49 INT5624 Transcription of Nppa 19 0.69 8.52 4.72
50 INT79902 Gene_expression of AQP1 33 0.78 24.72 4.55
51 INT5619 Positive_regulation of Gene_expression of Nppa 21 0.70 11.95 4.41
52 INT143337 Binding of Aqp4 30 0.40 23.73 4.24
53 INT19301 Regulation of Regulation of AVP 9 0.45 3.15 4.09
54 INT169748 Positive_regulation of Gene_expression of Aqp4 38 0.69 34.29 3.79
55 INT98624 Regulation of Aqp4 27 0.62 30.76 3.77
56 INT225965 Localization of Aqp4 26 0.81 18.85 3.75
57 INT130836 Transcription of Aqp4 6 0.72 5.93 3.52
58 INT18838 Positive_regulation of Regulation of Avp 3 0.47 0.48 3.32
59 INT30131 Positive_regulation of Negative_regulation of Avp 5 0.50 1.94 3.3
60 INT130835 Positive_regulation of Transcription of Aqp4 3 0.68 4.5 3.28
61 INT165821 Positive_regulation of Aqp4 27 0.70 24.37 3.22
62 INT157960 Regulation of AQP4 11 0.48 21.36 3.06
63 INT19553 Negative_regulation of Regulation of Avp 5 0.43 1.74 3.06
64 INT6193 Regulation of Gene_expression of Nppa 6 0.45 2.02 2.93
65 INT169747 Localization of AQP4 17 0.75 16.64 2.79
66 INT58166 Regulation of Gene_expression of Avp 13 0.57 2.63 2.76
67 INT10848 Negative_regulation of Gene_expression of AVP 13 0.59 6.76 2.71
68 INT11300 Positive_regulation of Gene_expression of Avp 24 0.50 10.18 2.69
69 INT53780 Binding of Avp 19 0.48 6.16 2.55
70 INT140414 Positive_regulation of AQP4 25 0.64 23.43 2.47
71 INT46159 Positive_regulation of Positive_regulation of AVP 4 0.50 1.24 2.45
72 INT20498 Negative_regulation of Positive_regulation of Nppa 9 0.59 4.5 2.43
73 INT225966 Regulation of Gene_expression of Aqp4 18 0.62 20.39 2.3
74 INT2611 Negative_regulation of AQP1 17 0.39 10.04 2.15
75 INT46160 Regulation of Positive_regulation of AVP 4 0.53 0.99 2.14
76 INT7375 Negative_regulation of Positive_regulation of AVP 6 0.43 0.37 1.97
77 INT25461 Negative_regulation of Regulation of Nppa 2 0.43 0.22 1.97
78 INT895 Negative_regulation of Binding of Avp 7 0.55 2.45 1.9
79 INT250272 Positive_regulation of Gene_expression of AQP4 11 0.54 9.79 1.85
80 INT106091 Negative_regulation of Transcription of Avp 4 0.59 0.23 1.72
81 INT164480 Negative_regulation of Gene_expression of Aqp4 14 0.58 10.84 1.52
82 INT11057 Protein_catabolism of Nppa 11 0.94 3.34 1.47
83 INT10852 Transcription of AVP 3 0.69 1.75 1.41
84 INT211054 Positive_regulation of AQP1 3 0.33 4.53 1.41
85 INT73553 Gene_expression of Aqp1 23 0.67 4.65 1.34
86 INT131977 Positive_regulation of Localization of Avp 6 0.55 4.9 1.31
87 INT10625 Regulation of Positive_regulation of Avp 4 0.44 1.06 1.04
88 INT25718 Negative_regulation of Negative_regulation of Avp 4 0.58 0.5 1.02
89 INT166889 Positive_regulation of Gene_expression of AQP1 10 0.70 6.43 0.99
90 INT183362 Regulation of AQP1 3 0.23 1.49 0.92
91 INT29759 Negative_regulation of Negative_regulation of Nppa 3 0.58 1.5 0.9
92 INT25539 Regulation of Gene_expression of AVP 9 0.45 2.74 0.89
93 INT51704 Phosphorylation of AVP 2 0.79 0.33 0.86
94 INT51703 Positive_regulation of Phosphorylation of AVP 1 0.49 0.09 0.86
95 INT16587 Regulation of Negative_regulation of Nppa 3 0.53 0.84 0.82
96 INT251679 Negative_regulation of Gene_expression of AQP4 2 0.38 10.37 0.77
97 INT149604 Regulation of Negative_regulation of AVP 2 0.44 0.49 0.77
98 INT235953 Regulation of Binding of Aqp4 4 0.45 4.4 0.76
99 INT16537 Regulation of Positive_regulation of Nppa 2 0.45 1.44 0.76
100 INT235951 Positive_regulation of Positive_regulation of Aqp4 4 0.57 5.13 0.75
101 INT16676 Regulation of Negative_regulation of Avp 2 0.45 1.03 0.75
102 INT5621 Positive_regulation of Transcription of Nppa 5 0.50 4.97 0.74
103 INT58165 Transcription of Avp 12 0.69 0.83 0.66
104 INT327779 Regulation of Gene_expression of AQP4 5 0.48 4.5 0.6
105 INT51718 Positive_regulation of Negative_regulation of Nppa 3 0.47 0.79 0.57
106 INT7293 Negative_regulation of Binding of Nppa 5 0.43 1.4 0.55
107 INT139780 Binding of AQP1 7 0.32 4.62 0.54
108 INT6567 Positive_regulation of Regulation of AVP 2 0.67 0.93 0.51
109 INT5625 Regulation of Transcription of Nppa 2 0.26 0.29 0.46
110 INT19592 Localization of AQP1 4 0.81 1.09 0.44
111 INT327786 Negative_regulation of Gene_expression of AQP1 3 0.29 4.21 0.44
112 INT111869 Protein_catabolism of AVP 3 0.64 0.63 0.42
113 INT6563 Positive_regulation of Regulation of Nppa 1 0.33 0.44 0.41
114 INT72821 Negative_regulation of Gene_expression of Avp 8 0.59 3.63 0.4
115 INT31738 Negative_regulation of Regulation of AVP 3 0.37 1.36 0.4
116 INT32533 Negative_regulation of Gene_expression of Nppa 2 0.32 1.93 0.38
117 INT299223 Negative_regulation of Transcription of Aqp4 3 0.59 1.36 0.35
118 INT235950 Regulation of Regulation of Aqp4 1 0.37 1.96 0.34
119 INT41233 Regulation of Binding of Avp 1 0.24 0.33 0.32
120 INT58161 Positive_regulation of Transcription of Avp 2 0.37 0.58 0.31
121 INT112982 Negative_regulation of Localization of Avp 1 0.07 0.49 0.3
122 INT35611 Positive_regulation of Binding of AVP 1 0.43 0.19 0.28
123 INT17158 Regulation of Protein_catabolism of Nppa 1 0.24 0.1 0.28
124 INT247863 Positive_regulation of Negative_regulation of Aqp4 3 0.45 2.63 0.25
125 INT235946 Positive_regulation of Localization of Aqp4 1 0.41 1.32 0.25
126 INT247870 Negative_regulation of Localization of Aqp4 3 0.43 2 0.24
127 INT327785 Transcription of AQP4 3 0.56 2.19 0.23
128 INT235947 Regulation of Localization of Aqp4 1 0.37 1.25 0.22
129 INT147667 Negative_regulation of Positive_regulation of Avp 2 0.11 0.27 0.21
130 INT250270 Regulation of Localization of AQP4 1 0.41 0.22 0.2
131 INT159640 Negative_regulation of Regulation of Aqp4 1 0.42 0.78 0.18
132 INT327780 Negative_regulation of Negative_regulation of AQP4 1 0.33 1.12 0.18
133 INT84554 Regulation of Regulation of Nppa 1 0.27 0.39 0.18
134 INT215814 Negative_regulation of Gene_expression of Aqp1 2 0.31 0.25 0.17
135 INT39283 Regulation of Positive_regulation of Avp 1 0.27 0.33 0.17
136 INT250280 Positive_regulation of Negative_regulation of AQP4 1 0.37 0.58 0.17
137 INT11058 Positive_regulation of Protein_catabolism of Nppa 1 0.37 0.53 0.17
138 INT98625 Regulation of Aqp1 1 0.27 0.1 0.17
139 INT308436 Protein_catabolism of Avp 2 0.64 1.27 0.15
140 INT200585 Negative_regulation of Binding of AVP 3 0.39 0.61 0.14
141 INT250279 Positive_regulation of Localization of AQP4 1 0.46 0.69 0.13
142 INT332570 Phosphorylation of Aqp4 1 0.59 0.9 0.13
143 INT280773 Phosphorylation of Avp 1 0.09 0.17 0.12
144 INT215820 Negative_regulation of Aqp1 3 0.23 0.83 0.1
145 INT159343 Positive_regulation of Localization of AQP1 1 0.11 0 0.1
146 INT58163 Negative_regulation of Transcription of Avp 2 0.43 0 0.09
147 INT54037 Positive_regulation of Positive_regulation of Avp 1 0.07 1.01 0.09
148 INT58162 Positive_regulation of Negative_regulation of Avp 1 0.37 0 0.09
149 INT265698 Regulation of Transcription of Avp 2 0.45 0.18 0.07
150 INT262510 Regulation of Gene_expression of Aqp1 1 0.33 1.18 0.07
151 INT327778 Positive_regulation of Regulation of AQP4 1 0.37 2.84 0.07
152 INT218755 Positive_regulation of Regulation of Avp 1 0.03 0.74 0.04
153 INT235949 Regulation of Positive_regulation of Aqp4 1 0.37 0 0.03
154 INT262504 Positive_regulation of Aqp1 1 0.25 0.43 0
155 INT286264 Positive_regulation of Negative_regulation of AQP1 1 0.01 0.79 0
156 INT327783 Regulation of Transcription of AQP4 1 0.35 1.03 0
157 INT262513 Negative_regulation of Binding of Aqp1 1 0.23 0.64 0
158 INT247864 Positive_regulation of Protein_catabolism of Aqp4 1 0.45 0.41 0
159 INT54038 Regulation of Localization of Avp 1 0.03 0.33 0
160 INT262514 Binding of Aqp1 1 0.20 0.64 0
161 INT327788 Regulation of Regulation of AQP4 1 0.21 0.75 0
162 INT26142 Positive_regulation of Binding of Avp 1 0.43 0.21 0
163 INT299193 Transcription of Aqp1 1 0.56 0.62 0
164 INT200581 Negative_regulation of Negative_regulation of AVP 1 0.41 0.46 0
165 INT247880 Protein_catabolism of Aqp4 1 0.64 1.35 0
166 INT262511 Positive_regulation of Gene_expression of Aqp1 1 0.37 1.78 0
167 INT331644 Protein_catabolism of Avp 1 0.65 0 0
168 INT327782 Regulation of Gene_expression of AQP1 1 0.36 1.63 0
169 INT331645 Positive_regulation of Protein_catabolism of Avp 1 0.46 0 0
170 INT262512 Localization of Aqp1 1 0.40 0.7 0
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