GO:0050901

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Name leukocyte tethering or rolling
Categary Process
Go Slim No
Go Link GO:0050901
Unique Molecular Interactions 1414
Total Molecular Interactions 1975
Total Single Events 20866
Pain Genes Associated 19

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for leukocyte tethering or rolling. They are ordered first by their pain relevance and then by number of times they were reported for leukocyte tethering or rolling. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT139706 Tnf Positive_regulation of Ltp 1 0.03 2.61 4.63
2 INT61359 TNF Positive_regulation of NFKB1 11 0.63 6.66 3.89
3 INT146412 Tnf Positive_regulation of Gene_expression of Trpv1 2 0.66 5.22 3.22
4 INT130085 Crp Positive_regulation of Gene_expression of Vcam1 1 0.23 4.34 2.84
5 INT83169 Binding of Cck and Lep 7 0.42 1.58 2.78
6 INT278948 LEP Positive_regulation of Gene_expression of PTGER2 1 0.09 4.04 2.69
7 INT140024 Tnf Positive_regulation of Gene_expression of Il1b 2 0.49 2.75 2.61
8 INT152501 Binding of Tnf and Tnfrsf1a 4 0.31 3 2.58
9 INT151826 Tnf Positive_regulation of TNF 1 0.04 3.38 2.51
10 INT117532 SETBP1 Positive_regulation of Gene_expression of TNF 1 0.54 0.85 2.44
11 INT122163 Binding of TNF and TNFRSF1B 6 0.44 6.06 2.41
12 INT61733 Tlr4 Positive_regulation of Gene_expression of Tnf 3 0.26 1.99 2.36
13 INT139705 Negative_regulation of Tnf Positive_regulation of Ltp 1 0.03 1.19 2.3
14 INT279361 Binding of TNF and KLF1 4 0.00 3.72 2.19
15 INT94491 Il1b Positive_regulation of Gene_expression of Tnf 1 0.25 3.81 2.19
16 INT94504 Il6 Positive_regulation of Gene_expression of Tnf 1 0.30 3.8 2.19
17 INT86179 TNF Positive_regulation of Localization of IL6 5 0.35 1.66 2.17
18 INT148704 Binding of TNF and TNFRSF1A 5 0.44 3.3 2.09
19 INT196586 Negative_regulation of Mapk14 Negative_regulation of TNF 2 0.04 2.02 2.08
20 INT140032 Tnf Positive_regulation of Gene_expression of Ifng 2 0.43 2.23 2
21 INT140026 Il1b Positive_regulation of Gene_expression of Tnf 2 0.49 2.23 2
22 INT278937 LEP Positive_regulation of Gene_expression of IL6 1 0.32 3.42 1.97
23 INT83170 Lep Regulation of Cck 5 0.43 0.68 1.96
24 INT217042 IRF6 Positive_regulation of TNF 4 0.27 3.03 1.95
25 INT129212 RYBP Positive_regulation of Tnf 2 0.03 1.9 1.95
26 INT279359 Binding of ADA and TNF 1 0.20 2.61 1.91
27 INT267133 Binding of ICAM1 and VCAM1 25 0.32 25.43 1.83
28 INT199287 TNF Positive_regulation of Transcription of Oprm1 2 0.02 1.86 1.8
29 INT224432 TNF Positive_regulation of Gene_expression of VEGFA 1 0.13 5.83 1.8
30 INT100771 Binding of Itga1 and Vcam1 3 0.11 3.91 1.79
31 INT137207 Tnf Positive_regulation of Nfkb1 3 0.23 2.69 1.71
32 INT167427 Mapk8 Regulation of Regulation of Tnf 1 0.26 2.83 1.7
33 INT89379 TNF Positive_regulation of Gene_expression of IL6 5 0.50 4.37 1.69
34 INT79778 Tlr4 Positive_regulation of Localization of TNF 4 0.08 4.21 1.61
35 INT167202 TNF Regulation of Gene_expression of Ngf 1 0.10 1.47 1.6
36 INT209853 TNF Regulation of Gene_expression of CD36 1 0.61 3.41 1.59
37 INT266767 SFTPA1 Positive_regulation of Gene_expression of TNF 1 0.01 1.69 1.59
38 INT89011 Lep Positive_regulation of Insr 1 0.19 2.41 1.57
39 INT198653 TNF Positive_regulation of MIF 1 0.15 3.81 1.55
40 INT252633 Binding of TNF and Tnfrsf1b 4 0.05 3.66 1.54
41 INT167201 Gtf3a Regulation of TNF 1 0.01 1.39 1.52
42 INT158775 Regulation of Tnf Regulation of Ephb1 1 0.18 0.09 1.52
43 INT158777 Tnf Regulation of Ephb1 1 0.18 0.09 1.51
44 INT140029 Ifng Positive_regulation of Gene_expression of Tnf 1 0.43 1.69 1.5
45 INT285569 TNF Negative_regulation of Gene_expression of Il6 1 0.03 2.83 1.46
46 INT72755 Tap1 Negative_regulation of TNF 1 0.43 2.45 1.46
47 INT131156 Binding of RUNX1 and TNF 2 0.03 3.44 1.42
48 INT161513 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Tnf 1 0.33 0.27 1.35
49 INT160588 TNF Positive_regulation of Gene_expression of OPRM1 1 0.20 0.54 1.35
50 INT56087 TNF Regulation of Gene_expression of SERPINE1 1 0.43 1.67 1.33
51 INT186393 Binding of TNF and Tnfrsf1a 9 0.37 8.55 1.29
52 INT130333 FUT3 Negative_regulation of Positive_regulation of Tnf 1 0.01 0.36 1.29
53 INT177232 ICAM1 Regulation of Gene_expression of Vcam1 1 0.03 5.52 1.28
54 INT70037 TNF Regulation of IL10 2 0.09 2.11 1.26
55 INT296796 Tbrs1 Positive_regulation of Gene_expression of TNF 1 0.00 1.58 1.26
56 INT151657 Vcam1 Regulation of Gene_expression of ICAM1 1 0.00 2.86 1.24
57 INT197092 TNF Regulation of VEGFA 4 0.21 2.78 1.22
58 INT131807 Bpifa2 Positive_regulation of Localization of Tnf 1 0.32 2.09 1.22
59 INT70035 TNF Regulation of Negative_regulation of PRF1 1 0.05 1.42 1.21
60 INT70032 TNF Regulation of PRF1 1 0.05 1.42 1.21
61 INT70040 TNF Regulation of Negative_regulation of IL10 1 0.09 1.42 1.21
62 INT328743 TNF Positive_regulation of Mapk14 1 0.04 1.4 1.21
63 INT194619 Il15 Positive_regulation of Gene_expression of TNF 1 0.24 2.23 1.2
64 INT133046 TNF Positive_regulation of Positive_regulation of NFKB1 5 0.54 3.23 1.19
65 INT113242 TNF Regulation of Transcription of OPRM1 2 0.45 1.53 1.19
66 INT314196 Ngf Positive_regulation of Tnf 1 0.50 1.98 1.18
67 INT231769 TNF Negative_regulation of Gene_expression of HMOX1 1 0.26 4.75 1.15
68 INT72754 Adamts7 Negative_regulation of TNF 1 0.28 1.64 1.13
69 INT89938 Tlr4 Positive_regulation of Gene_expression of TNF 6 0.25 1.3 1.12
70 INT107264 Binding of TNF and NCR3 1 0.30 1.42 1.1
71 INT139704 Tnf Positive_regulation of Mapk14 1 0.22 0.73 1.1
72 INT107266 Binding of HLA-DRB1 and TNF 1 0.29 1.41 1.1
73 INT267597 IL10 Negative_regulation of Gene_expression of TNF 1 0.03 2.24 1.1
74 INT107267 Binding of HLA-A and TNF 1 0.34 1.41 1.1
75 INT94495 Tnf Positive_regulation of Gene_expression of Il6 1 0.30 1.9 1.09
76 INT151825 Tnf Positive_regulation of Mapk14 1 0.22 1.72 1.09
77 INT94500 Tnf Positive_regulation of Gene_expression of Il1b 1 0.25 1.9 1.09
78 INT139703 Tnf Positive_regulation of Mapk8 1 0.32 0.73 1.08
79 INT152502 Tnf Negative_regulation of Binding of Tnfrsf1a 1 0.37 0.6 1.08
80 INT119108 Binding of LTBR and TNF 2 0.15 1.47 1.07
81 INT114364 Hmgb1 Positive_regulation of Gene_expression of TNF 2 0.05 1.85 1.06
82 INT120312 Ghrh Regulation of Tnf 1 0.26 0.95 1.05
83 INT120314 Ghrh Regulation of Positive_regulation of Tnf 1 0.43 0.95 1.05
84 INT152504 Binding of CR1 and Tnf 1 0.00 0.49 1.04
85 INT133650 Epo Negative_regulation of TNF 1 0.35 2.7 1.04
86 INT156245 NFKB1 Positive_regulation of Regulation of TNF 1 0.45 0.76 1.03
87 INT81545 Tnf Positive_regulation of Gtf3a 2 0.03 1.41 1.02
88 INT101317 Binding of Selplg and Selp 1 0.02 3.72 1.01
89 INT117311 HP Positive_regulation of Lep 1 0.00 1.78 1.01
90 INT278962 LEP Positive_regulation of CPOX 1 0.05 1.33 1
91 INT308804 Pld1 Positive_regulation of TNF 1 0.05 2.42 0.99
92 INT274895 Positive_regulation of Cbr2 Negative_regulation of Gene_expression of TNF 1 0.06 1.21 0.99
93 INT103796 IL1B Positive_regulation of Gene_expression of SELE 2 0.08 1 0.98
94 INT129216 Negative_regulation of RYBP Positive_regulation of Tnf 1 0.01 1.24 0.98
95 INT182022 TNF Positive_regulation of Gene_expression of Tnfrsf11b 1 0.06 1.56 0.98
96 INT209852 TNF Negative_regulation of Gene_expression of CD36 1 0.43 0.61 0.98
97 INT154255 Tnf Positive_regulation of IL1B 1 0.54 0.94 0.97
98 INT154254 Tnf Positive_regulation of Il6 1 0.36 0.94 0.97
99 INT114320 TNF Positive_regulation of Gene_expression of Il6 1 0.07 1.73 0.97
100 INT103133 TNF Positive_regulation of Gene_expression of IL8 2 0.48 1.26 0.96
101 INT278940 LEP Positive_regulation of Gene_expression of IL8 1 0.34 1.68 0.96
102 INT133652 Epo Negative_regulation of Gene_expression of TNF 1 0.35 2.64 0.96
103 INT171264 TNF Positive_regulation of MMP1 2 0.10 2.05 0.95
104 INT188805 TNF Positive_regulation of Gene_expression of Crp 1 0.15 2.96 0.95
105 INT100018 TNF Positive_regulation of MAPK1 3 0.24 1.56 0.94
106 INT133050 TNF Positive_regulation of Gene_expression of ICAM1 3 0.67 1.91 0.94
107 INT182024 TNF Positive_regulation of Gene_expression of Il6 1 0.05 1.58 0.94
108 INT129211 RYBP Positive_regulation of Gene_expression of Tnf 1 0.01 1.04 0.94
109 INT155259 RUNX1 Negative_regulation of Tnf 1 0.00 1.48 0.93
110 INT165280 Tnf Positive_regulation of Gene_expression of Nos2 1 0.24 1.02 0.91
111 INT254242 TNF Positive_regulation of Gene_expression of DKK1 1 0.14 1.24 0.91
112 INT256646 Tnf Positive_regulation of Positive_regulation of Nfkb1 1 0.22 1.83 0.9
113 INT222988 TNF Positive_regulation of Protein_catabolism of COL1A1 1 0.01 1.66 0.9
114 INT211128 Binding of P4HB and TNF 1 0.09 0.97 0.9
115 INT211129 Negative_regulation of Binding of P4HB and TNF 1 0.10 0.97 0.9
116 INT120147 Tlr4 Positive_regulation of Tnf 3 0.39 2.14 0.89
117 INT80132 Binding of HLA-B and TNF 1 0.04 1.15 0.89
118 INT142278 Slc8a1 Regulation of Tnf 1 0.14 0.07 0.89
119 INT167466 Ccdc80 Negative_regulation of Tnf 1 0.01 0.76 0.88
120 INT134311 Tnf Positive_regulation of Protein_catabolism of Nfkbia 1 0.18 0.57 0.88
121 INT116556 Olr1627 Negative_regulation of Regulation of Tnf 1 0.01 1.52 0.87
122 INT97795 IRF6 Positive_regulation of Localization of TNF 3 0.09 1.57 0.86
123 INT152868 Tnf Regulation of Gene_expression of Trpv1 1 0.27 0.25 0.86
124 INT110315 Negative_regulation of ALOX5 Negative_regulation of Gene_expression of TNF 1 0.47 0.74 0.85
125 INT215598 Positive_regulation of P2rx7 Positive_regulation of Localization of TNF 1 0.22 1.44 0.85
126 INT196638 TNF Positive_regulation of F2RL1 2 0.09 1.52 0.84
127 INT146919 Tnf Positive_regulation of Gene_expression of Ccl2 1 0.16 1.44 0.84
128 INT238641 Binding of TNF and Ifx 1 0.07 0.86 0.84
129 INT238642 Binding of TNF and Ada 1 0.03 0.86 0.84
130 INT105435 TNF Positive_regulation of IL6 5 0.25 4.45 0.83
131 INT149626 Il1b Regulation of Gene_expression of Tnf 1 0.41 0.83 0.83
132 INT102201 Tnf Regulation of Il1b 3 0.39 2.57 0.82
133 INT162071 Gene_expression of MC1R Negative_regulation of Gene_expression of TNF 1 0.41 0.34 0.82
134 INT66206 Negative_regulation of TNF Positive_regulation of NFKB1 2 0.53 1.71 0.81
135 INT126555 Binding of Ighg1 and Tnf 1 0.35 2.2 0.8
136 INT147755 Binding of GNRH1 and TNF 1 0.32 2.37 0.79
137 INT110518 Tnf Positive_regulation of Prkce 1 0.26 1.43 0.78
138 INT188531 Binding of TNF and PDXK 1 0.03 1.99 0.78
139 INT102163 Binding of TNF and Mmp9 1 0.12 0.88 0.78
140 INT306259 HDAC9 Negative_regulation of Gene_expression of TNF 1 0.21 0.89 0.78
141 INT102161 Binding of TNF and Mmp2 1 0.10 0.88 0.78
142 INT306258 HDAC4 Negative_regulation of Gene_expression of TNF 1 0.09 0.89 0.78
143 INT130138 TNF Negative_regulation of Gene_expression of S100A10 1 0.06 1.32 0.78
144 INT130948 Amt Regulation of Gene_expression of LEP 1 0.00 1.04 0.78
145 INT102162 Binding of TNF and Adam17 1 0.14 0.88 0.78
146 INT130949 Amt Regulation of LEP 1 0.00 1.04 0.77
147 INT296797 Tlr9 Regulation of Positive_regulation of TNF 1 0.03 1.37 0.77
148 INT296798 Gopc Regulation of Positive_regulation of TNF 1 0.01 1.37 0.77
149 INT152869 Tnf Positive_regulation of Gene_expression of Trpv1 1 0.46 0.48 0.77
150 INT209883 TNF Positive_regulation of Gene_expression of TNFRSF11A 1 0.20 1.83 0.77
151 INT194644 Tlr4 Positive_regulation of TNF 6 0.58 2.42 0.76
152 INT149192 TNF Positive_regulation of Gene_expression of VCAM1 3 0.57 1.4 0.76
153 INT173112 IL1B Positive_regulation of Gene_expression of VCAM1 2 0.43 1.34 0.76
154 INT26497 TNF Positive_regulation of Gene_expression of MMP2 1 0.44 1.5 0.75
155 INT113472 TNF Positive_regulation of Localization of MMP14 1 0.47 0.45 0.75
156 INT308176 TNF Regulation of Tnfrsf1a 1 0.05 1.19 0.75
157 INT278958 LEP Positive_regulation of IL1B 1 0.33 1.91 0.74
158 INT354455 Il11 Negative_regulation of Gene_expression of Tnf 1 0.31 1.21 0.74
159 INT301141 Nsa2 Positive_regulation of TNF 1 0.01 0.6 0.74
160 INT301142 Negative_regulation of Nsa2 Positive_regulation of TNF 1 0.01 0.6 0.74
161 INT4875 TNF Regulation of MME 1 0.51 0.71 0.74
162 INT86657 TNF Regulation of H2-Ab1 1 0.02 0.84 0.74
163 INT190174 TNF Positive_regulation of MMP12 1 0.27 0.08 0.74
164 INT214163 Binding of Lep and Nts 1 0.04 0.21 0.74
165 INT96301 Olr1742 Negative_regulation of Gene_expression of Tnf 1 0.14 0 0.74
166 INT211127 Regulation of Binding of MTX1 and TNF 1 0.22 0.71 0.74
167 INT211130 Binding of MTX1 and TNF 1 0.18 0.7 0.73
168 INT172147 Binding of IL15 and TNF 2 0.05 1.19 0.72
169 INT150992 Sfpq Negative_regulation of Gene_expression of Tnf 1 0.03 0.69 0.72
170 INT51006 PDYN Positive_regulation of TNF 1 0.11 0.84 0.72
171 INT117535 SND1 Positive_regulation of Gene_expression of TNF 1 0.06 0.29 0.71
172 INT113499 TNF Positive_regulation of Gene_expression of BHLHE23 1 0.25 0.1 0.71
173 INT159963 Tnf Positive_regulation of Localization of Il6 1 0.12 2.32 0.71
174 INT187115 Binding of TIMP1 and TNF 2 0.30 1.07 0.7
175 INT171901 Binding of TNF and Il1 2 0.18 1.07 0.7
176 INT117534 TNF Positive_regulation of Positive_regulation of SND1 1 0.06 0.29 0.7
177 INT117533 TNF Positive_regulation of Positive_regulation of SETBP1 1 0.34 0.29 0.7
178 INT83628 TNF Positive_regulation of Gene_expression of Cd59 1 0.06 1.09 0.7
179 INT172143 IL4 Positive_regulation of Protein_catabolism of TNF 2 0.11 1.7 0.69
180 INT89009 Lep Positive_regulation of Cck 2 0.67 0.43 0.69
181 INT172146 IL10 Positive_regulation of Protein_catabolism of TNF 2 0.15 1.69 0.69
182 INT278956 LEP Regulation of Gene_expression of IL8 1 0.30 1.11 0.69
183 INT278968 LEP Regulation of Gene_expression of IL6 1 0.29 1.11 0.69
184 INT83625 Tnf Positive_regulation of Gene_expression of Cd59 1 0.15 1.08 0.69
185 INT73823 TFF2 Positive_regulation of Gene_expression of VCAM1 1 0.04 0.59 0.69
186 INT334395 IL1B Positive_regulation of Tnf 1 0.11 2.83 0.69
187 INT278951 LEP Regulation of Gene_expression of PTGER2 1 0.07 1.11 0.69
188 INT113959 TNF Positive_regulation of Gene_expression of IK 1 0.02 0.66 0.69
189 INT190527 TNF Positive_regulation of Gene_expression of Ros1 1 0.01 1.02 0.68
190 INT119107 Negative_regulation of Binding of LTBR and TNF 1 0.17 1.16 0.68
191 INT79937 TAC1 Positive_regulation of Gene_expression of VCAM1 1 0.20 0.15 0.68
192 INT203758 Binding of IL6 and TNF 3 0.26 2.03 0.67
193 INT231349 Il10 Negative_regulation of Gene_expression of TNF 2 0.23 1.82 0.67
194 INT119105 Binding of FCGR1A and TNF 1 0.03 1.16 0.67
195 INT119106 Negative_regulation of Binding of FCGR1A and TNF 1 0.03 1.16 0.67
196 INT264338 Binding of IL-17 and Positive_regulation of Localization of TNF 1 0.04 1.71 0.67
197 INT314199 Mapk14 Regulation of Tnf 1 0.26 0.71 0.67
198 INT278965 LEP Positive_regulation of Gene_expression of NOS2 2 0.29 2.12 0.66
199 INT148139 Phosphorylation of Mapk14 Positive_regulation of Positive_regulation of Tnf 1 0.46 0.98 0.66
200 INT137142 Binding of ITIH4 and Positive_regulation of Localization of TNF 1 0.40 0.71 0.66

Single Events

The table below shows the top 100 pain related interactions that have been reported for leukocyte tethering or rolling. They are ordered first by their pain relevance and then by number of times they were reported in leukocyte tethering or rolling. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82
2 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98
3 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81
4 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68
5 INT6852 Localization of TNF 883 0.81 705.95 270.84
6 INT6481 Binding of TNF 624 0.48 510.2 214.82
7 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210
8 INT6488 Gene_expression of Tnf 484 0.78 339.61 191.58
9 INT13353 Positive_regulation of Tnf 332 0.70 248.75 148.1
10 INT9660 Regulation of TNF 363 0.62 312.94 139.99
11 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61
12 INT10166 Localization of Tnf 237 0.81 153.95 88.64
13 INT9236 Regulation of Gene_expression of TNF 204 0.62 162.66 72.99
14 INT58400 Negative_regulation of Tnf 182 0.59 129.97 71
15 INT49995 Positive_regulation of Gene_expression of Tnf 187 0.70 125.07 70.54
16 INT6489 Positive_regulation of Gene_expression of Tnf 140 0.70 92.31 67.85
17 INT6486 Positive_regulation of Tnf 168 0.70 123.47 66.05
18 INT52800 Negative_regulation of Gene_expression of Tnf 142 0.59 92.27 55.47
19 INT22112 Positive_regulation of Localization of TNF 164 0.70 115.66 52.18
20 INT17881 Gene_expression of LEP 278 0.78 221.61 48.31
21 INT66029 Negative_regulation of Tnf 100 0.59 84.28 48.16
22 INT55670 Negative_regulation of Gene_expression of Tnf 83 0.59 57.16 46.33
23 INT5307 Regulation of Tnf 87 0.62 78.71 43.4
24 INT49105 Gene_expression of Vcam1 157 0.78 157.27 43.01
25 INT13354 Transcription of TNF 108 0.72 85.81 42.32
26 INT47939 Gene_expression of Selp 171 0.76 87.54 39.03
27 INT53577 Negative_regulation of Localization of TNF 110 0.59 59.28 35.23
28 INT62830 Gene_expression of VCAM1 149 0.78 125.23 32.4
29 INT35406 Localization of Tnf 94 0.81 64.63 31.65
30 INT52801 Regulation of Gene_expression of Tnf 55 0.62 48.74 26.59
31 INT101483 Gene_expression of Lep 159 0.78 104.77 25.12
32 INT49141 Gene_expression of Selp 157 0.78 85.22 24.78
33 INT49196 Gene_expression of SELE 105 0.78 107.29 22.92
34 INT76123 Gene_expression of Lep 193 0.78 94.17 22.76
35 INT66753 Negative_regulation of Positive_regulation of Tnf 45 0.59 35.28 22.33
36 INT8483 Positive_regulation of Positive_regulation of TNF 73 0.67 60.35 22.03
37 INT53575 Regulation of Gene_expression of Tnf 46 0.62 34.35 20.63
38 INT82434 Positive_regulation of LEP 117 0.70 95.45 20.22
39 INT49103 Positive_regulation of Vcam1 71 0.69 59.52 19.85
40 INT53574 Regulation of Tnf 45 0.62 40.68 19.71
41 INT49487 Gene_expression of Sele 65 0.76 68.11 19.41
42 INT66751 Negative_regulation of Localization of Tnf 48 0.59 26 19.36
43 INT66755 Transcription of Tnf 45 0.72 37.1 19.11
44 INT61257 Gene_expression of Sele 79 0.77 70.97 17.78
45 INT10169 Positive_regulation of Localization of Tnf 44 0.70 27.71 16.75
46 INT19929 Negative_regulation of Positive_regulation of TNF 52 0.59 38.16 16.51
47 INT49986 Transcription of Tnf 25 0.72 18.3 16.22
48 INT62681 Negative_regulation of LEP 93 0.59 66.97 15.77
49 INT75908 Regulation of LEP 77 0.60 60.16 15.19
50 INT12087 Regulation of Localization of TNF 44 0.62 28.71 15.17
51 INT10173 Binding of Tnf 45 0.48 35.6 14.32
52 INT64048 Positive_regulation of Positive_regulation of Tnf 32 0.70 21.24 13.74
53 INT6478 Negative_regulation of Binding of TNF 36 0.58 30.42 13.31
54 INT71510 Positive_regulation of Selp 47 0.68 30.43 12.8
55 INT89404 Regulation of Negative_regulation of TNF 30 0.45 24.47 12.71
56 INT73641 Regulation of Lep 45 0.62 26.2 12.59
57 INT73829 Positive_regulation of Gene_expression of VCAM1 41 0.61 35.96 11.92
58 INT49142 Gene_expression of SELP 94 0.75 54.61 11.64
59 INT126743 Positive_regulation of Gene_expression of LEP 61 0.66 50.02 11.17
60 INT82079 Positive_regulation of Lep 79 0.70 40 11.07
61 INT51265 Phosphorylation of TNF 32 0.81 25.33 10.75
62 INT60434 Negative_regulation of Positive_regulation of Tnf 20 0.46 10.01 10.64
63 INT101481 Positive_regulation of Lep 81 0.69 62.59 9.95
64 INT76573 Negative_regulation of Vcam1 26 0.58 24.36 9.84
65 INT80110 Regulation of Positive_regulation of TNF 34 0.44 25.79 9.78
66 INT82078 Negative_regulation of Lep 54 0.59 20.47 9.38
67 INT62829 Positive_regulation of VCAM1 39 0.70 38.42 9.15
68 INT48860 Regulation of Localization of Tnf 25 0.61 20.68 8.78
69 INT82082 Localization of Lep 63 0.81 26.41 8.56
70 INT53573 Negative_regulation of Localization of Tnf 19 0.59 11.57 8.54
71 INT75907 Binding of LEP 53 0.46 46.65 8.44
72 INT51458 Negative_regulation of Gene_expression of Selp 29 0.57 12.64 8.1
73 INT67424 Positive_regulation of Gene_expression of Selp 36 0.68 17.08 7.95
74 INT86411 Negative_regulation of Negative_regulation of TNF 24 0.42 17.6 7.89
75 INT81399 Regulation of Vcam1 24 0.46 23.53 7.68
76 INT49104 Positive_regulation of Gene_expression of Vcam1 30 0.69 36.52 7.64
77 INT49490 Positive_regulation of Transcription of TNF 19 0.70 14.76 7.58
78 INT68299 Binding of Tnf 17 0.39 12.55 7.49
79 INT66752 Positive_regulation of Transcription of Tnf 15 0.68 10.86 7.26
80 INT63169 Positive_regulation of Gene_expression of Selp 35 0.69 21.95 7.16
81 INT81880 Positive_regulation of Gene_expression of Sele 30 0.48 27.54 7.05
82 INT69985 Positive_regulation of Negative_regulation of TNF 21 0.50 13.26 6.31
83 INT63170 Positive_regulation of Selp 27 0.68 24.1 6.3
84 INT172084 Positive_regulation of Binding of TNF 21 0.50 15.31 6.06
85 INT67060 Negative_regulation of Transcription of TNF 17 0.59 12.94 5.88
86 INT74109 Positive_regulation of Sele 26 0.48 22.32 5.84
87 INT123563 Negative_regulation of Rock1 7 0.55 16.56 5.78
88 INT146594 Negative_regulation of Gene_expression of LEP 25 0.42 18.88 5.71
89 INT120550 Negative_regulation of Rock1 27 0.42 18.38 5.66
90 INT101482 Negative_regulation of Lep 53 0.54 33.59 5.65
91 INT6487 Positive_regulation of Positive_regulation of Tnf 21 0.56 16.06 5.64
92 INT58145 Positive_regulation of Localization of Tnf 20 0.67 13.33 5.44
93 INT65356 Localization of LEP 46 0.79 41.17 5.43
94 INT91338 Binding of Lep 31 0.48 26.86 5.39
95 INT62525 Positive_regulation of SELE 38 0.70 46 5.25
96 INT49801 Positive_regulation of SELP 21 0.48 21.34 5.25
97 INT102935 Regulation of Lep 31 0.60 18.47 5.24
98 INT62832 Negative_regulation of Gene_expression of SELE 16 0.49 10.6 5.12
99 INT92054 Positive_regulation of Transcription of Tnf 8 0.50 4.93 5.05
100 INT62822 Positive_regulation of Gene_expression of SELE 22 0.66 28.04 4.97
101 INT99001 Negative_regulation of Selp 23 0.59 16.68 4.74
102 INT55698 Regulation of Binding of TNF 13 0.44 8.98 4.74
103 INT97391 Binding of Lep 18 0.48 8.97 4.47
104 INT61036 Negative_regulation of Selp 12 0.50 7.45 4.46
105 INT62821 Negative_regulation of Gene_expression of VCAM1 21 0.54 12.24 4.41
106 INT130083 Positive_regulation of Positive_regulation of Vcam1 8 0.36 5.81 4.31
107 INT117551 Regulation of Gene_expression of Selp 15 0.44 7.32 4.2
108 INT62526 Negative_regulation of SELE 17 0.51 15.24 4.19
109 INT63977 Positive_regulation of Sele 28 0.68 18.49 4.17
110 INT163581 Localization of Lep 27 0.79 18.99 4.08
111 INT66754 Negative_regulation of Transcription of Tnf 11 0.43 8.43 3.93
112 INT23088 Phosphorylation of Tnf 15 0.79 9.85 3.82
113 INT172173 Protein_catabolism of TNF 16 0.96 9.95 3.79
114 INT119606 Regulation of Gene_expression of LEP 17 0.45 17.96 3.75
115 INT174054 Positive_regulation of Gene_expression of Lep 25 0.69 21.3 3.72
116 INT63979 Regulation of Sele 13 0.54 10.64 3.7
117 INT67423 Regulation of Gene_expression of Selp 16 0.60 7.4 3.68
118 INT9256 Gene_expression of SELPLG 30 0.75 16.44 3.66
119 INT61253 Negative_regulation of Sele 13 0.57 11.68 3.56
120 INT106264 Negative_regulation of Gene_expression of Vcam1 13 0.53 10.47 3.55
121 INT73802 Regulation of Selp 17 0.60 8.72 3.51
122 INT82077 Positive_regulation of Gene_expression of Lep 32 0.70 17.9 3.5
123 INT63425 Positive_regulation of Gene_expression of SELP 23 0.67 15.34 3.48
124 INT130557 Negative_regulation of Gene_expression of Selp 17 0.54 6.56 3.45
125 INT76501 Binding of Selp 16 0.41 8.51 3.4
126 INT65427 Regulation of Positive_regulation of Tnf 7 0.60 3.49 3.22
127 INT77604 Positive_regulation of Binding of VCAM1 4 0.47 6.54 3.06
128 INT59719 Localization of SELP 12 0.78 8.4 2.95
129 INT51460 Negative_regulation of Gene_expression of Sele 8 0.52 10.18 2.89
130 INT77602 Binding of VCAM1 8 0.41 8.66 2.86
131 INT95049 Negative_regulation of Regulation of Tnf 4 0.42 1.64 2.84
132 INT28891 Localization of Selp 13 0.60 8.23 2.83
133 INT81411 Negative_regulation of Sele 8 0.38 7 2.7
134 INT156579 Localization of Selp 14 0.73 6.53 2.69
135 INT75736 Regulation of Localization of Tnf 6 0.62 4.61 2.67
136 INT97443 Positive_regulation of Positive_regulation of LEP 13 0.50 11.91 2.65
137 INT79938 Regulation of Gene_expression of VCAM1 12 0.61 11.22 2.64
138 INT98607 Regulation of Regulation of TNF 8 0.44 6.95 2.56
139 INT73671 Regulation of Gene_expression of Sele 8 0.45 7.01 2.39
140 INT103487 Positive_regulation of Positive_regulation of Lep 9 0.67 4.08 2.38
141 INT122290 Regulation of Gene_expression of Vcam1 9 0.42 7.15 2.26
142 INT66804 Negative_regulation of Negative_regulation of Tnf 4 0.56 2.79 2.26
143 INT114898 Regulation of Transcription of TNF 4 0.35 2.69 2.18
144 INT96084 Binding of Selp 12 0.48 8.41 2.16
145 INT82081 Regulation of Gene_expression of Lep 11 0.53 7.78 2.12
146 INT83392 Transcription of Lep 6 0.54 5.07 2.04
147 INT122649 Positive_regulation of Regulation of Tnf 2 0.49 2.78 1.96
148 INT173116 Regulation of VCAM1 14 0.33 11.85 1.92
149 INT66794 Binding of Vcam1 14 0.48 7.84 1.87
150 INT77801 Negative_regulation of Binding of Tnf 5 0.42 3.93 1.77
151 INT82083 Negative_regulation of Gene_expression of Lep 12 0.56 8.07 1.75
152 INT101314 Gene_expression of Selplg 10 0.75 5.63 1.71
153 INT93004 Positive_regulation of Positive_regulation of VCAM1 3 0.47 2.93 1.66
154 INT159957 Positive_regulation of Phosphorylation of Tnf 3 0.49 2.63 1.65
155 INT99150 Localization of VCAM1 7 0.79 6.2 1.6
156 INT61256 Negative_regulation of Transcription of Sele 2 0.43 1.24 1.6
157 INT61261 Transcription of Sele 2 0.53 1.24 1.58
158 INT183791 Positive_regulation of Phosphorylation of TNF 6 0.49 4.72 1.56
159 INT61967 Positive_regulation of Negative_regulation of Tnf 3 0.50 2.46 1.49
160 INT100549 Negative_regulation of SELP 6 0.43 4.17 1.46
161 INT112562 Binding of SELP 11 0.34 6.25 1.44
162 INT214115 Regulation of Gene_expression of Lep 9 0.61 7.37 1.44
163 INT83659 Negative_regulation of Binding of Tnf 3 0.37 1.57 1.42
164 INT28892 Positive_regulation of Localization of Selp 3 0.35 1.04 1.4
165 INT61263 Negative_regulation of Gene_expression of Sele 6 0.43 5.65 1.31
166 INT63978 Regulation of Gene_expression of Sele 5 0.18 4.59 1.24
167 INT168720 Regulation of Negative_regulation of Rock1 1 0.43 1.31 1.23
168 INT167270 Negative_regulation of Gene_expression of Lep 13 0.55 5.48 1.19
169 INT100548 Regulation of SELP 8 0.29 8.56 1.17
170 INT9257 Positive_regulation of SELPLG 5 0.45 3.57 1.16
171 INT213465 Transcription of Lep 4 0.68 2.11 1.15
172 INT180095 Gene_expression of Rock1 22 0.55 4.9 1.14
173 INT72864 Positive_regulation of Gene_expression of Sele 9 0.68 7.46 1.14
174 INT126534 Negative_regulation of ROCK1 18 0.49 14.32 1.13
175 INT253813 Regulation of Negative_regulation of Lep 2 0.45 1.01 1.12
176 INT82084 Positive_regulation of Localization of Lep 11 0.70 4.65 1.11
177 INT146198 Positive_regulation of Rock1 16 0.49 5.86 1.1
178 INT263403 Positive_regulation of Rock1 3 0.38 4.68 1.09
179 INT111858 Regulation of Rock1 1 0.41 0.75 1.09
180 INT62823 Negative_regulation of Positive_regulation of VCAM1 2 0.43 0.48 1.08
181 INT129587 Protein_catabolism of Tnf 2 0.86 1.41 1.08
182 INT83465 Positive_regulation of Localization of Sele 1 0.09 2.81 1.08
183 INT83463 Localization of Sele 1 0.14 2.81 1.08
184 INT168276 Negative_regulation of Phosphorylation of Tnf 1 0.19 1.3 1.08
185 INT135027 Regulation of Positive_regulation of Tnf 3 0.38 2.84 1.05
186 INT78050 Positive_regulation of Positive_regulation of Selp 3 0.43 3.63 1.02
187 INT272918 Positive_regulation of Positive_regulation of SELE 2 0.03 2.24 0.96
188 INT183471 Positive_regulation of Localization of VCAM1 1 0.34 1.5 0.95
189 INT115471 Binding of Sele 5 0.36 4.06 0.94
190 INT99149 Negative_regulation of VCAM1 4 0.36 3.29 0.93
191 INT134307 Negative_regulation of Protein_catabolism of Tnf 1 0.41 0.57 0.88
192 INT112783 Regulation of Gene_expression of SELE 6 0.40 6.82 0.87
193 INT115822 Regulation of Transcription of Tnf 3 0.35 1.96 0.87
194 INT134310 Positive_regulation of Protein_catabolism of Tnf 1 0.49 0.57 0.87
195 INT117308 Negative_regulation of Localization of Lep 3 0.59 2.16 0.86
196 INT98994 Regulation of Selp 10 0.45 3.91 0.83
197 INT333883 Positive_regulation of Positive_regulation of Lep 2 0.46 1.06 0.83
198 INT116866 Regulation of Sele 6 0.45 4.07 0.82
199 INT146199 Negative_regulation of Negative_regulation of Rock1 1 0.22 0.7 0.8
200 INT136690 Regulation of Negative_regulation of Tnf 5 0.45 3.58 0.78
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