GO:0050904

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Name diapedesis
Categary Process
Go Slim No
Go Link GO:0050904
Unique Molecular Interactions 85
Total Molecular Interactions 142
Total Single Events 1548
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for diapedesis. They are ordered first by their pain relevance and then by number of times they were reported for diapedesis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT181455 Binding of Ccr5 and Ccl5 11 0.39 12.13 3.66
2 INT189488 Binding of Ccr1 and Ccl5 8 0.40 9.26 3.27
3 INT182635 Binding of CCR5 and CCL5 2 0.09 4.19 3
4 INT318996 Binding of CCR3 and CCL5 1 0.07 3.39 2.9
5 INT319003 Binding of CCR1 and CCL5 1 0.08 3.38 2.89
6 INT189490 Binding of Ccr3 and Ccl5 1 0.33 8.54 2.6
7 INT149494 PNOC Negative_regulation of Gene_expression of CCL5 1 0.19 0.52 2.46
8 INT149557 Tgfb1 Positive_regulation of Gene_expression of Ccl5 1 0.00 0 0.82
9 INT87490 CALCA Positive_regulation of Gene_expression of CCL5 1 0.30 0.14 0.81
10 INT182814 Binding of ICAM1 and PECAM1 2 0.02 3.32 0.77
11 INT149493 PNOC Negative_regulation of CCL5 1 0.14 0.16 0.77
12 INT170127 Binding of ITGAL and PECAM1 2 0.01 2.71 0.75
13 INT176473 IL10 Positive_regulation of Gene_expression of PECAM1 1 0.05 1.1 0.75
14 INT258644 Binding of CCL2 and CCL5 1 0.36 1.6 0.74
15 INT258643 Positive_regulation of Binding of CCL2 and CCL5 1 0.49 1.61 0.74
16 INT297313 Negative_regulation of Binding of Ccr1 and Ccl5 1 0.28 0.74 0.67
17 INT245299 Ccl5 Positive_regulation of Localization of IL8 1 0.11 2.87 0.66
18 INT182819 Binding of CD63 and PECAM1 1 0.00 1.63 0.61
19 INT316831 CCL5 Positive_regulation of Gene_expression of MMP2 1 0.02 0.51 0.59
20 INT254637 Bdkrb2 Regulation of Gene_expression of Ccl5 1 0.17 1.22 0.56
21 INT171278 TNFSF12 Positive_regulation of CCL5 1 0.02 0.93 0.48
22 INT147279 Binding of Calca and Pecam1 1 0.33 0.4 0.47
23 INT181444 Ccl5 Positive_regulation of Csf2 1 0.07 1.88 0.45
24 INT343853 IRF6 Positive_regulation of PECAM1 1 0.00 0.53 0.43
25 INT147280 Binding of Pecam1 and Th 1 0.29 0.41 0.41
26 INT186758 Il13 Regulation of Ccl5 2 0.17 0.17 0.39
27 INT316830 TNF Regulation of CCL5 1 0.02 1.02 0.39
28 INT189491 Icam1 Positive_regulation of Transcription of Ccl5 1 0.19 0.64 0.36
29 INT140474 Tnfrsf1a Positive_regulation of PECAM1 1 0.00 1.18 0.3
30 INT181432 Csf2 Positive_regulation of Ccl5 1 0.03 0.81 0.29
31 INT170258 Pecam1 Positive_regulation of Icam1 1 0.02 0.79 0.27
32 INT103279 PGR Negative_regulation of Gene_expression of CCL5 1 0.32 0.31 0.27
33 INT237088 Binding of Cxcl9 and Ccl5 1 0.29 1.51 0.26
34 INT246438 Ccl5 Positive_regulation of Gene_expression of Cd79a 1 0.13 0.83 0.26
35 INT266802 Dlst Positive_regulation of CCL5 1 0.00 0.95 0.25
36 INT252815 Binding of CCL5 and TNF 1 0.02 0.75 0.25
37 INT76224 Ptgs1 Regulation of Gene_expression of PECAM1 1 0.00 0.25 0.25
38 INT80286 IFNG Positive_regulation of Gene_expression of CCL5 1 0.24 0.37 0.23
39 INT80287 IL4 Positive_regulation of Gene_expression of CCL5 1 0.21 0.37 0.23
40 INT196635 CFTR Positive_regulation of Gene_expression of CCL5 1 0.07 0.44 0.21
41 INT295713 PTGER2 Positive_regulation of Regulation of CCL5 1 0.01 0.82 0.21
42 INT170995 Binding of IFNA1 and Positive_regulation of Localization of CCL5 1 0.03 0.34 0.19
43 INT338898 Binding of PECAM1 and PTPN11 1 0.04 0.38 0.19
44 INT303937 Positive_regulation of Binding of GLI2 and CCL5 1 0.01 0 0.18
45 INT303940 Regulation of Binding of GLI2 and CCL5 1 0.01 0 0.18
46 INT226344 Gene_expression of IL9 Positive_regulation of CCL5 1 0.07 1.03 0.18
47 INT303938 Binding of GLI2 and CCL5 1 0.01 0 0.18
48 INT246437 Ccl5 Positive_regulation of Regulation of Hand1 1 0.19 0.76 0.17
49 INT329795 IL6 Positive_regulation of Transcription of CCL5 1 0.02 0.59 0.17
50 INT267138 Binding of CDH5 and PECAM1 2 0.16 2.69 0.16
51 INT171945 PECAM1 Positive_regulation of Gene_expression of ICAM1 1 0.06 1.66 0.16
52 INT141759 Nfkb1 Regulation of PECAM1 1 0.01 1.18 0.16
53 INT171544 PECAM1 Positive_regulation of ICAM1 1 0.01 0.47 0.16
54 INT171944 ICAM1 Positive_regulation of Gene_expression of PECAM1 1 0.06 1.66 0.16
55 INT141762 Nfkb1 Regulation of Positive_regulation of PECAM1 1 0.01 1.21 0.16
56 INT246440 Ccl5 Positive_regulation of Positive_regulation of Xcl1 1 0.27 1.28 0.16
57 INT171295 CXCL10 Positive_regulation of CCL5 1 0.04 0.06 0.12
58 INT234060 Nes Positive_regulation of Pecam1 1 0.34 0.08 0.11
59 INT118052 Binding of Pecam1 and Cd34 1 0.22 0.51 0.1
60 INT338901 Binding of PECAM1 and PTPN6 1 0.03 0.18 0.1
61 INT186767 Ccl11 Regulation of Ccl5 1 0.01 0 0.07
62 INT171297 TNF Positive_regulation of Localization of CCL5 1 0.17 0.66 0.07
63 INT291837 Binding of Pecam1 and Vegfa 1 0.09 1.1 0.07
64 INT186766 Il5 Regulation of Ccl5 1 0.01 0 0.07
65 INT246441 Ccl5 Positive_regulation of Gene_expression of Aif1 1 0.03 0.71 0.06
66 INT171847 Binding of PECAM1 and VCAM1 1 0.01 1 0.06
67 INT246436 Ccl5 Regulation of Aif1 1 0.01 0.67 0.06
68 INT156143 MLL Positive_regulation of PECAM1 1 0.00 0.47 0.06
69 INT122216 IL1B Positive_regulation of CCL5 3 0.67 0.53 0.04
70 INT247774 Binding of Ccl5 and Ccrl2 1 0.14 0.29 0.04
71 INT171279 IL6 Positive_regulation of CCL5 1 0.04 0.38 0.04
72 INT171301 TNF Positive_regulation of CCL5 1 0.16 0.38 0.04
73 INT247766 Binding of Ccl2 and Ccl5 1 0.14 0.28 0.04
74 INT122217 IL1B Positive_regulation of Gene_expression of CCL5 2 0.52 0.08 0
75 INT213746 Binding of Pecam1 and Epc1 1 0.09 0 0
76 INT170119 PECAM1 Regulation of Positive_regulation of ITGAL 1 0.01 1.07 0
77 INT170120 PECAM1 Regulation of ITGAM 1 0.00 1.07 0
78 INT170118 PECAM1 Regulation of CD44 1 0.01 1.07 0
79 INT170123 ITGAL Regulation of Positive_regulation of PECAM1 1 0.01 1.07 0
80 INT127690 TNF Positive_regulation of Regulation of CCL5 1 0.33 0.17 0
81 INT171282 TNFSF12 Positive_regulation of Gene_expression of CCL5 1 0.01 0 0
82 INT170125 ITGAM Regulation of Positive_regulation of PECAM1 1 0.01 1.07 0
83 INT170126 PECAM1 Regulation of ITGB2 1 0.01 1.07 0
84 INT296210 Binding of Pecam1 and Tg(CAG-EGFP)D4Nagy 1 0.01 0.13 0
85 INT170115 PECAM1 Regulation of ITGAL 1 0.00 1.07 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for diapedesis. They are ordered first by their pain relevance and then by number of times they were reported in diapedesis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT78899 Gene_expression of CCL5 155 0.77 84.02 55.09
2 INT63349 Gene_expression of PECAM1 199 0.75 166.03 36.76
3 INT130186 Gene_expression of Ccl5 101 0.74 79.96 25.01
4 INT78901 Localization of CCL5 67 0.78 40.79 20.59
5 INT89594 Gene_expression of Ccl5 44 0.54 24.08 18.62
6 INT85964 Gene_expression of Pecam1 109 0.78 69.73 15.21
7 INT82684 Positive_regulation of Pecam1 27 0.49 25.67 11.47
8 INT168409 Positive_regulation of Ccl5 47 0.64 45.84 10.83
9 INT4240 Positive_regulation of CCL5 32 0.58 20.55 10.65
10 INT78895 Regulation of CCL5 30 0.46 20.45 10.18
11 INT87495 Positive_regulation of Gene_expression of CCL5 26 0.69 13.85 9.46
12 INT82685 Gene_expression of Pecam1 36 0.76 27.95 9.01
13 INT102351 Regulation of Pecam1 7 0.61 22.45 7.58
14 INT85968 Positive_regulation of Pecam1 19 0.69 29.04 7.5
15 INT89589 Negative_regulation of Ccl5 9 0.40 4.62 7.39
16 INT181348 Localization of Ccl5 24 0.65 19.55 6.8
17 INT92470 Negative_regulation of Gene_expression of CCL5 15 0.50 5.46 5.86
18 INT63351 Negative_regulation of Gene_expression of PECAM1 19 0.52 16.06 5.73
19 INT181363 Regulation of Ccl5 16 0.46 13.65 5.09
20 INT181362 Negative_regulation of Ccl5 21 0.40 15.63 4.96
21 INT82887 Positive_regulation of Ccl5 10 0.40 3.4 4.91
22 INT176614 Positive_regulation of Gene_expression of Ccl5 20 0.59 16.2 4.81
23 INT82354 Positive_regulation of PECAM1 25 0.34 22.93 4.69
24 INT89590 Negative_regulation of Gene_expression of Ccl5 8 0.36 3.97 4.67
25 INT87632 Positive_regulation of Gene_expression of PECAM1 32 0.45 29.47 4.66
26 INT181042 Binding of Ccl5 18 0.41 9.34 4.51
27 INT4239 Negative_regulation of CCL5 15 0.40 10.92 4.26
28 INT51898 Binding of PECAM1 26 0.36 18.87 4.22
29 INT124655 Negative_regulation of PECAM1 13 0.23 10.32 3.78
30 INT103281 Transcription of CCL5 10 0.67 5.95 3.7
31 INT89592 Localization of Ccl5 10 0.61 7.65 3.62
32 INT181378 Negative_regulation of Gene_expression of Ccl5 12 0.46 9.64 3.59
33 INT124123 Positive_regulation of Localization of CCL5 12 0.67 7 3.37
34 INT181418 Regulation of Gene_expression of Ccl5 11 0.52 9.86 3.37
35 INT82879 Regulation of Ccl5 9 0.30 6.19 3.17
36 INT78898 Regulation of Gene_expression of CCL5 9 0.42 5.7 3.11
37 INT115617 Binding of Ccl5 5 0.33 0.58 3.11
38 INT194661 Binding of CCL5 9 0.46 6.07 2.73
39 INT76713 Regulation of Gene_expression of PECAM1 16 0.40 14.52 2.51
40 INT84881 Positive_regulation of Gene_expression of Pecam1 5 0.46 5.79 2.35
41 INT102979 Negative_regulation of Gene_expression of Pecam1 5 0.40 4.95 2.21
42 INT115616 Positive_regulation of Binding of Ccl5 3 0.25 0.59 2.04
43 INT103061 Positive_regulation of Gene_expression of Ccl5 4 0.35 1.67 1.9
44 INT51896 Localization of PECAM1 11 0.47 9.8 1.78
45 INT194660 Positive_regulation of Binding of CCL5 1 0.42 2.74 1.72
46 INT78896 Negative_regulation of Localization of CCL5 8 0.57 2.43 1.59
47 INT67708 Binding of Pecam1 9 0.32 3.12 1.58
48 INT171015 Positive_regulation of Positive_regulation of CCL5 3 0.42 3.63 1.51
49 INT85967 Positive_regulation of Gene_expression of Pecam1 6 0.50 6.22 1.39
50 INT115895 Phosphorylation of Ccl5 1 0.55 0 1.31
51 INT269185 Regulation of Gene_expression of Pecam1 2 0.45 3.75 1.24
52 INT151513 Negative_regulation of Gene_expression of Pecam1 8 0.37 4.73 1.22
53 INT349026 Positive_regulation of Regulation of Pecam1 1 0.46 3.9 1.17
54 INT149554 Transcription of Ccl5 2 0.59 0.55 1.14
55 INT115893 Negative_regulation of Binding of Ccl5 1 0.37 0 1.14
56 INT102978 Negative_regulation of Pecam1 2 0.48 2.24 1.01
57 INT208244 Regulation of Gene_expression of Ccl5 1 0.26 1.92 1.01
58 INT63348 Regulation of PECAM1 14 0.40 16.05 0.97
59 INT181351 Transcription of Ccl5 5 0.64 2.19 0.9
60 INT103285 Regulation of Localization of CCL5 3 0.44 1.11 0.89
61 INT149555 Negative_regulation of Positive_regulation of Ccl5 1 0.15 0 0.88
62 INT83948 Transcription of PECAM1 2 0.09 2.97 0.87
63 INT181390 Negative_regulation of Positive_regulation of Ccl5 2 0.31 2.31 0.77
64 INT320992 Positive_regulation of Positive_regulation of Pecam1 5 0.50 4.23 0.73
65 INT115897 Positive_regulation of Phosphorylation of Ccl5 1 0.41 0 0.66
66 INT181349 Positive_regulation of Localization of Ccl5 2 0.37 0.89 0.62
67 INT145537 Regulation of Localization of PECAM1 3 0.18 4.86 0.59
68 INT194225 Positive_regulation of Positive_regulation of Ccl5 1 0.07 1.13 0.55
69 INT349025 Regulation of Regulation of Pecam1 1 0.27 1.51 0.52
70 INT114831 Localization of Pecam1 3 0.65 3.85 0.47
71 INT187466 Localization of Pecam1 6 0.47 1.65 0.46
72 INT144101 Negative_regulation of Negative_regulation of Pecam1 1 0.43 1.96 0.46
73 INT194658 Positive_regulation of Transcription of CCL5 1 0.45 0.68 0.44
74 INT267606 Protein_catabolism of CCL5 2 0.48 1.39 0.43
75 INT91152 Regulation of Pecam1 4 0.30 4.14 0.42
76 INT144100 Negative_regulation of Pecam1 4 0.59 3.65 0.42
77 INT140465 Negative_regulation of Positive_regulation of PECAM1 2 0.01 2.11 0.39
78 INT268760 Positive_regulation of Binding of Ccl5 1 0.13 0.91 0.39
79 INT322698 Protein_catabolism of Ccl5 1 0.49 0.33 0.38
80 INT195733 Phosphorylation of CCL5 2 0.10 1.04 0.33
81 INT267141 Regulation of Binding of PECAM1 2 0.18 3.2 0.32
82 INT253290 Negative_regulation of Binding of Pecam1 1 0.31 2.86 0.32
83 INT267142 Phosphorylation of PECAM1 2 0.61 2.35 0.27
84 INT159362 Binding of Pecam1 2 0.23 0.89 0.27
85 INT267148 Positive_regulation of Phosphorylation of PECAM1 2 0.37 2.36 0.27
86 INT103283 Negative_regulation of Transcription of CCL5 1 0.50 0.28 0.27
87 INT322710 Positive_regulation of Transcription of Ccl5 1 0.43 0.56 0.26
88 INT349024 Protein_catabolism of Pecam1 1 0.88 0.35 0.25
89 INT282377 Regulation of Positive_regulation of CCL5 1 0.05 1.12 0.22
90 INT141758 Positive_regulation of Positive_regulation of PECAM1 1 0.01 1.21 0.16
91 INT89593 Negative_regulation of Localization of Ccl5 1 0.03 0.46 0.15
92 INT233838 Regulation of Binding of Ccl5 1 0.21 1 0.15
93 INT195730 Negative_regulation of Binding of CCL5 1 0.05 0.51 0.13
94 INT114832 Positive_regulation of Localization of Pecam1 1 0.40 1.6 0.11
95 INT246434 Negative_regulation of Negative_regulation of Ccl5 1 0.40 1.72 0.09
96 INT325664 Regulation of Positive_regulation of Pecam1 1 0.27 0.57 0.04
97 INT325667 Regulation of Binding of Pecam1 1 0.27 0.62 0.03
98 INT102977 Negative_regulation of Positive_regulation of Pecam1 1 0.35 0 0
99 INT179114 Positive_regulation of Phosphorylation of Pecam1 1 0.14 0.45 0
100 INT325668 Positive_regulation of Phosphorylation of Pecam1 1 0.30 0.41 0
101 INT170139 Negative_regulation of Regulation of PECAM1 1 0.02 0.19 0
102 INT179108 Phosphorylation of Pecam1 1 0.19 0.45 0
103 INT123315 Transcription of Pecam1 1 0.13 0 0
104 INT123316 Transcription of Pecam1 1 0.14 0 0
105 INT104463 Regulation of Gene_expression of Pecam1 1 0.44 0.19 0
106 INT189478 Regulation of Transcription of Ccl5 1 0.38 0.63 0
107 INT172188 Positive_regulation of Transcription of PECAM1 1 0.08 1.21 0
108 INT325671 Phosphorylation of Pecam1 1 0.48 0.41 0
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