GO:0050913

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Name sensory perception of bitter taste
Categary Process
Go Slim No
Go Link GO:0050913
Unique Molecular Interactions 97
Total Molecular Interactions 151
Total Single Events 709
Pain Genes Associated 4

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for sensory perception of bitter taste. They are ordered first by their pain relevance and then by number of times they were reported for sensory perception of bitter taste. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT297488 Itpr3 Regulation of Positive_regulation of Ltp 1 0.02 0.47 1.87
2 INT124874 Gnat3 Positive_regulation of Localization of Calca 2 0.08 0.75 1.2
3 INT124878 Gnat3 Negative_regulation of Gene_expression of FOS 1 0.09 0.16 0.85
4 INT124877 Gnat3 Negative_regulation of FOS 1 0.09 0.15 0.82
5 INT124876 Gnat3 Negative_regulation of Positive_regulation of FOS 1 0.09 0.15 0.82
6 INT261834 Itpr3 Positive_regulation of Prkca 2 0.01 0.33 0.78
7 INT297490 Itpr3 Regulation of Ltp 1 0.02 0 0.7
8 INT34006 Binding of ITPR3 and YY1 1 0.22 0.33 0.48
9 INT237810 Itpr3 Positive_regulation of Localization of Car2 2 0.08 0.68 0.45
10 INT337326 PIK3CD Positive_regulation of Localization of ITPR3 1 0.02 0 0.43
11 INT337324 PIK3CD Positive_regulation of Gene_expression of ITPR3 1 0.02 0 0.43
12 INT251430 Gnat3 Positive_regulation of Gucy1b2 1 0.04 0.48 0.42
13 INT33713 Binding of ITPR3 and Trh 1 0.00 0.86 0.39
14 INT251426 Gnat3 Negative_regulation of Aldh2 1 0.22 0 0.35
15 INT251420 Aldh3a1 Regulation of Gene_expression of Gnat3 1 0.09 0.08 0.28
16 INT189200 Binding of CA2 and ITPR3 3 0.03 1.9 0.27
17 INT247475 P2RY6 Positive_regulation of ITPR3 1 0.01 0.45 0.23
18 INT33714 Positive_regulation of Binding of ITPR3 and Trh 1 0.00 0.46 0.21
19 INT308645 Binding of Esr1 and Itpr3 1 0.00 0 0.2
20 INT199192 Gnat3 Positive_regulation of Hmox1 1 0.27 0.23 0.19
21 INT291788 ALDOA Positive_regulation of Gnat3 2 0.02 0.52 0.18
22 INT216601 Itpr3 Positive_regulation of Localization of Ca2 1 0.00 0.05 0.15
23 INT251435 Gnat3 Positive_regulation of NPR1 1 0.22 0.2 0.15
24 INT34451 Binding of Itpr3 and Ptprg 1 0.03 0 0.15
25 INT335459 ABCA1 Positive_regulation of ITPR3 1 0.00 0 0.15
26 INT251424 Positive_regulation of Gnat3 Positive_regulation of Gucy1b2 1 0.02 0.2 0.15
27 INT199195 Gnat3 Regulation of Transcription of Hmox1 1 0.24 0.12 0.14
28 INT251431 Negative_regulation of Gnat3 Positive_regulation of Gucy1b2 1 0.02 0.1 0.14
29 INT350735 PRKDC Negative_regulation of ITPR3 1 0.01 0.16 0.11
30 INT292383 Binding of Itpr3 and Mrvi1 1 0.18 0 0.11
31 INT327188 Gnat3 Regulation of PAEP 1 0.25 1.38 0.11
32 INT33712 Trh Positive_regulation of Localization of ITPR3 1 0.00 0.8 0.1
33 INT201747 Itpr3 Positive_regulation of Localization of Esr1 2 0.03 1.19 0.09
34 INT249183 Binding of ITPR3 and GOPC 2 0.01 0.26 0.09
35 INT113362 Gnat3 Positive_regulation of Serpina3c 1 0.17 0.25 0.09
36 INT350220 Positive_regulation of HSPG2 Positive_regulation of Localization of ITPR3 1 0.05 0.09 0.09
37 INT350216 ITPR3 Regulation of Localization of TNIP3 1 0.01 0.08 0.09
38 INT350217 Positive_regulation of HSPG2 Positive_regulation of ITPR3 1 0.05 0.09 0.09
39 INT174070 Htr2c Positive_regulation of Itpr3 1 0.00 0 0.09
40 INT237820 Binding of Itpr3 and soc 1 0.02 0 0.09
41 INT208979 Binding of Itpr3 and Trpc3 1 0.00 0.33 0.09
42 INT199193 Gnat3 Positive_regulation of Gene_expression of Ros1 1 0.08 0.18 0.08
43 INT237814 Itpr3 Positive_regulation of Localization of Tmie 1 0.01 0.68 0.08
44 INT350218 Positive_regulation of HSPG2 Positive_regulation of Gene_expression of ITPR3 1 0.04 0.09 0.08
45 INT237815 Binding of Itpr3 and Stim1 1 0.04 0 0.07
46 INT327189 Gnat3 Regulation of Positive_regulation of PAEP 1 0.25 0.72 0.07
47 INT350219 ITPR3 Positive_regulation of CA2 1 0.22 0 0.05
48 INT251427 Gnat3 Positive_regulation of Aldh2 1 0.26 0 0.05
49 INT34447 Ptprg Positive_regulation of Itpr3 1 0.04 0 0.05
50 INT208988 Binding of CALM1 and Itpr3 1 0.01 0.15 0.05
51 INT208982 Negative_regulation of Binding of Itpr3 and Trpc3 1 0.00 0.17 0.04
52 INT291782 Binding of ALDH2 and Gnat3 1 0.12 0 0.04
53 INT251425 Aldh2 Negative_regulation of Negative_regulation of Gnat3 1 0.19 0 0.04
54 INT291781 Regulation of Binding of ALDH2 and Gnat3 1 0.11 0 0.04
55 INT291792 Regulation of Binding of ALDOA and Gnat3 1 0.02 0 0.04
56 INT291789 Binding of ALDOA and Gnat3 1 0.01 0 0.04
57 INT199196 Gnat3 Positive_regulation of Aldh2 2 0.26 1.06 0.03
58 INT291786 GOPC Negative_regulation of Gene_expression of Gnat3 1 0.01 0 0.03
59 INT318073 Itpr3 Regulation of Ca2 1 0.01 0 0.03
60 INT249159 HSPG2 Positive_regulation of Gene_expression of ITPR3 2 0.01 0.06 0
61 INT251419 Positive_regulation of Aldh2 Positive_regulation of Gnat3 1 0.20 0 0
62 INT279704 Binding of CIB1 and Positive_regulation of ITPR3 1 0.06 0.17 0
63 INT291783 ALDOA Regulation of Gnat3 1 0.01 0 0
64 INT331237 Negative_regulation of IMPA1 Negative_regulation of Itpr3 1 0.00 0.52 0
65 INT291787 Gnat3 Negative_regulation of ALDH2 1 0.11 0 0
66 INT251423 Gnat3 Regulation of Binding of Aldh3a1 1 0.09 0 0
67 INT292384 Itpr3 Regulation of Car2 1 0.07 0 0
68 INT31765 Positive_regulation of Binding of Itpr3 and Ca2 1 0.21 0 0
69 INT330428 Gnat3 Negative_regulation of Aldh2 1 0.11 0.44 0
70 INT292387 Lrmp Regulation of Itpr3 1 0.45 0.31 0
71 INT251418 Gnat3 Regulation of Aldh2 1 0.12 0 0
72 INT292386 Binding of Itpr3 and Lrmp 1 0.41 0.67 0
73 INT249176 Binding of ITPR3 and TRPC1 1 0.02 0 0
74 INT249163 Binding of CISH and ITPR3 1 0.00 0.5 0
75 INT251429 Aldh2 Positive_regulation of Gnat3 1 0.20 0 0
76 INT291791 ALDH2 Negative_regulation of Gnat3 1 0.15 0.06 0
77 INT159977 Binding of Mgst1 and Gnat3 1 0.03 0 0
78 INT65902 GSTK1 Regulation of Positive_regulation of Gnat3 1 0.02 0 0
79 INT251421 Binding of Gnat3 and Positive_regulation of Gene_expression of Aldh2 1 0.20 0 0
80 INT291784 Binding of SERPINE2 and Gnat3 1 0.00 0.3 0
81 INT251428 Aldh2 Negative_regulation of Gnat3 1 0.19 0 0
82 INT251422 Binding of Aldh2 and Gnat3 1 0.19 0 0
83 INT31766 Binding of Itpr3 and Ca2 1 0.16 0 0
84 INT291785 ALDH2 Regulation of Localization of Gnat3 1 0.11 0 0
85 INT291790 Negative_regulation of Binding of ALDH2 and Gnat3 1 0.11 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for sensory perception of bitter taste. They are ordered first by their pain relevance and then by number of times they were reported in sensory perception of bitter taste. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT31761 Positive_regulation of Itpr3 32 0.58 5.95 8.22
2 INT36040 Localization of Itpr3 21 0.70 4.87 7.77
3 INT26919 Gene_expression of ITPR3 47 0.42 5.86 5.79
4 INT34742 Gene_expression of Gnat3 44 0.67 6.83 5.65
5 INT26334 Localization of ITPR3 39 0.49 2.53 5.07
6 INT31762 Gene_expression of Itpr3 22 0.74 1.6 4.15
7 INT34829 Positive_regulation of Gnat3 27 0.46 5.24 4.14
8 INT26191 Positive_regulation of ITPR3 24 0.44 1.9 3.74
9 INT25136 Localization of Gnat3 23 0.75 5.01 3.65
10 INT37180 Negative_regulation of Itpr3 6 0.51 1.43 3.27
11 INT54999 Regulation of Itpr3 6 0.24 0.18 3.11
12 INT36039 Gene_expression of Itpr3 19 0.72 3.75 2.93
13 INT11196 Negative_regulation of Gnat3 26 0.37 3.14 2.69
14 INT26918 Positive_regulation of Gene_expression of ITPR3 14 0.27 2.31 2.41
15 INT37347 Positive_regulation of Itpr3 6 0.34 1.3 2.31
16 INT31763 Positive_regulation of Gene_expression of Itpr3 10 0.30 0.83 2.28
17 INT26335 Binding of ITPR3 22 0.18 3.3 2.27
18 INT63081 Localization of Itpr3 13 0.67 1.08 2.12
19 INT55000 Positive_regulation of Regulation of Itpr3 1 0.41 0 2.08
20 INT37181 Negative_regulation of Localization of Itpr3 3 0.37 0.83 1.97
21 INT120505 Negative_regulation of ITPR3 6 0.27 1.46 1.68
22 INT31760 Negative_regulation of Itpr3 5 0.23 0.84 1.61
23 INT37346 Positive_regulation of Localization of Itpr3 3 0.47 0.45 1.59
24 INT235401 Negative_regulation of Gene_expression of ITPR3 4 0.20 1.69 1.24
25 INT37241 Negative_regulation of Localization of ITPR3 7 0.13 1.22 1.05
26 INT116829 Regulation of Itpr3 2 0.39 0 1.02
27 INT55243 Positive_regulation of Positive_regulation of Itpr3 4 0.58 0.89 0.95
28 INT116830 Binding of Itpr3 10 0.45 0.29 0.78
29 INT31764 Negative_regulation of Positive_regulation of Itpr3 4 0.25 0 0.77
30 INT62887 Regulation of Gene_expression of ITPR3 3 0.14 0.95 0.76
31 INT129797 Negative_regulation of Binding of ITPR3 3 0.14 0.58 0.75
32 INT26333 Positive_regulation of Localization of ITPR3 6 0.43 0.17 0.68
33 INT26336 Regulation of Localization of ITPR3 2 0.13 0.37 0.61
34 INT59819 Phosphorylation of ITPR3 2 0.06 0 0.54
35 INT64935 Negative_regulation of Regulation of Itpr3 1 0.26 0 0.49
36 INT146402 Regulation of Gnat3 6 0.31 1.52 0.44
37 INT63082 Binding of Itpr3 12 0.12 0.54 0.39
38 INT58439 Negative_regulation of Gene_expression of Gnat3 4 0.42 0.88 0.39
39 INT55577 Negative_regulation of Gene_expression of Itpr3 1 0.06 0 0.39
40 INT77274 Protein_catabolism of Gnat3 1 0.83 0 0.34
41 INT240951 Positive_regulation of Positive_regulation of Itpr3 1 0.03 0.06 0.33
42 INT33706 Regulation of ITPR3 6 0.28 0.46 0.3
43 INT137334 Binding of Gnat3 8 0.41 0.61 0.28
44 INT55240 Regulation of Positive_regulation of Itpr3 1 0.52 0.48 0.28
45 INT149738 Regulation of Gene_expression of Itpr3 1 0.22 0.09 0.27
46 INT251390 Regulation of Gene_expression of Gnat3 2 0.28 0.52 0.26
47 INT113951 Positive_regulation of Gene_expression of Gnat3 2 0.13 0.26 0.25
48 INT216609 Protein_catabolism of Itpr3 2 0.24 0.42 0.14
49 INT25137 Positive_regulation of Localization of Gnat3 1 0.40 0.21 0.14
50 INT11197 Positive_regulation of Negative_regulation of Gnat3 1 0.06 0.2 0.14
51 INT237797 Positive_regulation of Gene_expression of Itpr3 3 0.05 1.08 0.11
52 INT199180 Transcription of Gnat3 1 0.47 0 0.09
53 INT281233 Positive_regulation of Protein_catabolism of Itpr3 1 0.11 0.16 0.08
54 INT272152 Positive_regulation of Positive_regulation of ITPR3 1 0.06 0 0.08
55 INT120506 Negative_regulation of Negative_regulation of ITPR3 1 0.01 0.08 0.08
56 INT281239 Negative_regulation of Protein_catabolism of Itpr3 1 0.10 0.16 0.07
57 INT216802 Positive_regulation of Localization of Itpr3 1 0.07 0 0.06
58 INT63083 Positive_regulation of Binding of Itpr3 2 0.11 0.16 0.04
59 INT181632 Regulation of Binding of Gnat3 1 0.06 0.27 0.04
60 INT33707 Positive_regulation of Transcription of ITPR3 1 0.01 0.27 0.04
61 INT33705 Transcription of ITPR3 1 0.02 0.27 0.04
62 INT249279 Regulation of Binding of ITPR3 1 0.03 0.44 0.04
63 INT249235 Positive_regulation of Binding of ITPR3 3 0.17 0.2 0.03
64 INT292373 Regulation of Gene_expression of Itpr3 1 0.57 0.14 0
65 INT251391 Negative_regulation of Negative_regulation of Gnat3 1 0.18 0 0
66 INT291748 Negative_regulation of Positive_regulation of Gnat3 1 0.10 0 0
67 INT292378 Regulation of Binding of Itpr3 1 0.25 0 0
68 INT292377 Regulation of Localization of Itpr3 1 0.37 0 0
69 INT291747 Regulation of Negative_regulation of Gnat3 1 0.12 0 0
70 INT281234 Negative_regulation of Binding of Itpr3 1 0.14 0 0
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