GO:0050919

From wiki-pain
Jump to: navigation, search
Name negative chemotaxis
Categary Process
Go Slim No
Go Link GO:0050919
Unique Molecular Interactions 166
Total Molecular Interactions 209
Total Single Events 951
Pain Genes Associated 13

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative chemotaxis. They are ordered first by their pain relevance and then by number of times they were reported for negative chemotaxis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT334532 Sema3a Negative_regulation of Gene_expression of Nrp1 1 0.19 7.58 2
2 INT271602 Binding of Pdgfa and Pdgfrl 1 0.02 0.86 1.25
3 INT260833 Binding of NRP2 and Flt1 1 0.00 3.61 1.22
4 INT96906 Plxna3 Regulation of Regulation of Prkaca 1 0.17 0.71 1.08
5 INT96905 Plxna3 Regulation of Regulation of Prkce 1 0.18 0.71 1.07
6 INT137441 Ngf Negative_regulation of Sema3a 1 0.46 2.07 1.01
7 INT334537 Sema3a Negative_regulation of Gene_expression of Plxna1 1 0.08 3.76 1
8 INT271601 Pdgfa Positive_regulation of Pdgfrl 1 0.03 0.83 0.91
9 INT260842 Binding of NRP2 and Kdr 1 0.00 2.28 0.85
10 INT67908 Binding of Cck and Plxna3 1 0.04 0.54 0.84
11 INT260832 Binding of NRP2 and Nrp1 1 0.00 2.32 0.7
12 INT260821 NRP2 Positive_regulation of Gene_expression of TNF 1 0.01 1.48 0.56
13 INT334526 Trpv1 Positive_regulation of Gene_expression of Sema3a 1 0.31 0.92 0.55
14 INT97949 Negative_regulation of NRP2 Negative_regulation of Positive_regulation of CDC42 1 0.06 0.72 0.51
15 INT97952 Negative_regulation of NRP2 Negative_regulation of Positive_regulation of AKT1 1 0.03 0.72 0.51
16 INT97950 Negative_regulation of NRP2 Negative_regulation of Positive_regulation of ST3GAL3 1 0.02 0.72 0.5
17 INT147444 PDGFA Positive_regulation of Gene_expression of Ros1 2 0.00 0.95 0.46
18 INT36340 Binding of NRP2 and Penk 1 0.04 0.07 0.39
19 INT137438 Ntf3 Regulation of Sema3a 1 0.06 0.82 0.35
20 INT137437 Nrtn Regulation of Sema3a 1 0.36 0.82 0.35
21 INT137439 Ntf3 Negative_regulation of Sema3a 1 0.02 0.77 0.34
22 INT137442 Nrtn Regulation of Sema3a 1 0.04 0.81 0.34
23 INT137440 Nrtn Negative_regulation of Sema3a 1 0.34 0.77 0.34
24 INT304339 Negative_regulation of CD79A Positive_regulation of NRP2 1 0.06 0.86 0.33
25 INT304338 CD79A Positive_regulation of NRP2 1 0.08 0.84 0.32
26 INT333398 CFD Negative_regulation of Gene_expression of Pdgfa 1 0.02 0.64 0.3
27 INT260841 Il6 Positive_regulation of Localization of NRP2 1 0.00 0.7 0.29
28 INT158733 Esr1 Regulation of Plxna3 1 0.03 0.27 0.29
29 INT347531 Binding of Nrp2 and Sema3b 1 0.04 0.99 0.28
30 INT260837 NRP2 Negative_regulation of Negative_regulation of Bcl2 1 0.00 0.9 0.28
31 INT162599 Wnt5a Regulation of Gene_expression of IL4I1 1 0.00 0.1 0.28
32 INT224457 TNF Positive_regulation of Pdgfa 1 0.34 1.22 0.27
33 INT332242 Binding of Egf and Pdgfa 1 0.07 0.97 0.25
34 INT260840 NRP2 Positive_regulation of Gene_expression of Bcl2 1 0.00 0.85 0.24
35 INT260835 NRP2 Positive_regulation of Eif2ak3 1 0.00 0.73 0.23
36 INT260844 NRP2 Positive_regulation of Akt1 1 0.00 0.73 0.22
37 INT193035 Positive_regulation of PDGFA Positive_regulation of EGF 1 0.05 0.53 0.21
38 INT193025 PDGFA Positive_regulation of EGF 1 0.05 0.53 0.21
39 INT193036 EGF Positive_regulation of PDGFA 1 0.05 0.53 0.21
40 INT193032 Positive_regulation of EGF Positive_regulation of PDGFA 1 0.05 0.53 0.21
41 INT332245 Pdgfa Positive_regulation of Stat6 1 0.07 1.22 0.19
42 INT192333 PDGFA Positive_regulation of Gene_expression of FN1 2 0.11 1.26 0.18
43 INT189563 Binding of SLIT2 and ROBO4 1 0.03 0.71 0.18
44 INT213561 Ngf Negative_regulation of Regulation of Sema3a 1 0.24 0.08 0.17
45 INT298717 Fgf2 Positive_regulation of Gene_expression of PDGFA 1 0.01 0.23 0.15
46 INT298716 Ngf Positive_regulation of Gene_expression of PDGFA 1 0.01 0.22 0.15
47 INT238331 PDGFA Regulation of Gene_expression of GOPC 1 0.04 0 0.14
48 INT238330 Binding of PDGFA and Regulation of Gene_expression of GOPC 1 0.06 0 0.14
49 INT332254 Pdgfa Positive_regulation of Stat3 1 0.02 0.52 0.14
50 INT213555 Bdnf Negative_regulation of Gene_expression of Sema3a 1 0.31 0.09 0.14
51 INT334527 Sema3a Negative_regulation of Gene_expression of Il4 1 0.15 0.48 0.14
52 INT238333 Binding of PDGFA and Regulation of Gene_expression of ADAMTS1 1 0.06 0 0.14
53 INT286900 Binding of HBM and PDGFA 1 0.04 1.08 0.14
54 INT155687 PDGFA Positive_regulation of Phosphorylation of FBRS 1 0.01 0.43 0.14
55 INT332256 Pdgfa Positive_regulation of SOAT1 1 0.01 0.51 0.14
56 INT332243 Pdgfa Positive_regulation of Stat1 1 0.06 0.52 0.14
57 INT334534 Nrp1 Negative_regulation of Gene_expression of Sema3a 1 0.17 0.48 0.14
58 INT238336 PDGFA Regulation of Negative_regulation of ADAMTS5 1 0.04 0 0.14
59 INT298715 Igf1 Positive_regulation of Gene_expression of PDGFA 1 0.00 0.22 0.14
60 INT223084 Binding of Pdgfa and Pdgfb 2 0.17 0.83 0.13
61 INT334530 Sema3a Regulation of Il18 1 0.18 1.61 0.13
62 INT334528 Nrp1 Negative_regulation of Sema3a 1 0.17 0.47 0.13
63 INT287884 WNT5A Positive_regulation of THEMIS 1 0.00 0.08 0.13
64 INT334524 Sema3a Regulation of Foxq1 1 0.04 1.61 0.13
65 INT261789 PDGFA Positive_regulation of Slc12a5 1 0.07 0.15 0.12
66 INT332250 Stat6 Positive_regulation of Gene_expression of Pdgfa 1 0.05 1.33 0.12
67 INT221628 Sema3a Regulation of Gh 1 0.01 0.39 0.12
68 INT224455 Pdgfa Regulation of VEGFA 1 0.07 0.22 0.11
69 INT221625 Fer Regulation of Localization of Sema3a 1 0.24 0.29 0.1
70 INT233510 Wnt5a Positive_regulation of Gene_expression of Il12a 1 0.03 0.33 0.1
71 INT146997 Binding of PLXNA3 and RLS 1 0.36 0.47 0.1
72 INT224026 P2RY6 Positive_regulation of NRP2 1 0.10 0.98 0.1
73 INT221668 Sema3a Positive_regulation of NPAT 1 0.36 0.47 0.09
74 INT221614 Binding of Sema3a and Fer 1 0.30 0.61 0.09
75 INT347302 PDGFA Positive_regulation of ITK 1 0.04 1.4 0.09
76 INT211960 Wnt5a Positive_regulation of Car2 1 0.13 0.38 0.08
77 INT287879 Binding of WNT5A and FZD5 1 0.06 1.16 0.08
78 INT251777 Negative_regulation of TXK Positive_regulation of PDGFA 1 0.04 1 0.08
79 INT251773 TXK Positive_regulation of PDGFA 1 0.04 1 0.08
80 INT179346 Pdgfa Positive_regulation of Positive_regulation of Mapk3 1 0.05 0.71 0.07
81 INT88411 Positive_regulation of PDGFA Positive_regulation of CDK2 1 0.11 0 0.07
82 INT231440 PDGFA Positive_regulation of Gene_expression of HGF 1 0.16 0.83 0.07
83 INT231434 FN1 Positive_regulation of Gene_expression of PDGFA 1 0.04 0.83 0.07
84 INT246539 EGF Negative_regulation of Gene_expression of PDGFA 1 0.06 0.38 0.07
85 INT88408 PDGFA Positive_regulation of CDK2 1 0.11 0 0.07
86 INT246538 PDGFA Negative_regulation of Gene_expression of EGF 1 0.06 0.38 0.07
87 INT179345 Pdgfa Positive_regulation of Mapk3 1 0.05 0.71 0.07
88 INT231441 PDGFA Positive_regulation of Gene_expression of VEGFA 1 0.17 0.83 0.07
89 INT279280 Binding of PDGFA and PDGFB 1 0.06 0.9 0.06
90 INT279291 PDGFA Positive_regulation of PDGFRB 1 0.16 1.02 0.06
91 INT279275 PDGFA Positive_regulation of TXK 1 0.05 1.02 0.06
92 INT279276 PDGFA Positive_regulation of NCOR2 1 0.00 1.02 0.06
93 INT221619 Binding of Ngf and Sema3a 1 0.17 0.54 0.06
94 INT244641 PDGFA Regulation of MTOR 1 0.07 2.55 0.06
95 INT221658 Sema3a Positive_regulation of Phosphorylation of Crmp1 1 0.12 0.4 0.05
96 INT221657 Sema3a Positive_regulation of Binding of Plxna1 1 0.01 0.39 0.05
97 INT173053 Binding of VEGFA and NRP2 3 0.12 1.36 0.04
98 INT173056 Binding of NRP2 and NRP1 2 0.24 0.61 0.04
99 INT311925 Binding of NRP2 and SEMA3A 1 0.26 0.06 0.04
100 INT311926 Binding of NRP1 and SEMA3A 1 0.26 0.48 0.04
101 INT315912 VEGFA Regulation of NRP2 1 0.04 0.32 0.04
102 INT179348 Pdgfa Positive_regulation of Binding of Pscs 1 0.04 0.38 0.03
103 INT302051 AAVS1 Positive_regulation of Gene_expression of Nrp2 1 0.02 0.33 0.03
104 INT179347 Pdgfa Positive_regulation of Pscs 1 0.04 0.38 0.03
105 INT221661 Sema3a Positive_regulation of Phosphorylation of Cdk5 1 0.19 0.28 0.03
106 INT288134 Pdgfa Regulation of Ifi35 1 0.01 0.78 0.03
107 INT221640 Sema3a Positive_regulation of Phosphorylation of Fyn 1 0.16 0.29 0.03
108 INT221626 Gopc Regulation of Sema3a 1 0.06 0.13 0.03
109 INT179344 Pdgfa Positive_regulation of Binding of Jun 1 0.00 0.38 0.03
110 INT354835 Binding of VEGFA and Pdgfa 1 0.00 1.5 0.03
111 INT311927 AASDH Positive_regulation of NRP2 1 0.02 0.1 0.03
112 INT347533 Tmem131 Negative_regulation of Gene_expression of Nrp2 1 0.04 0 0
113 INT353192 Stat5a Positive_regulation of Plxna3 1 0.01 0 0
114 INT347304 PDGFA Positive_regulation of Gene_expression of AKT1 1 0.19 0.6 0
115 INT352995 IPMK Regulation of PDGFA 1 0.00 0.66 0
116 INT353189 Plxna3 Negative_regulation of Cyp4a8 1 0.01 0.35 0
117 INT221644 Binding of Nptx1 and Sema3a 1 0.12 0.19 0
118 INT276285 Binding of SEPHS1 and PLXNA3 1 0.00 0.41 0
119 INT315868 Vhl Positive_regulation of Transcription of PDGFA 1 0.00 1.39 0
120 INT335884 Akt1 Regulation of Positive_regulation of Wnt5a 1 0.03 0.15 0
121 INT192328 UBR7 Regulation of Phosphorylation of PDGFA 1 0.00 0 0
122 INT311948 Binding of NRP1 and Plxna3 1 0.05 0.26 0
123 INT311947 Binding of SEMA3A and Plxna3 1 0.07 0.26 0
124 INT315856 FLT3 Positive_regulation of Gene_expression of PDGFA 1 0.01 1.15 0
125 INT335883 Binding of Lrp6 and Wnt5a 1 0.27 0.08 0
126 INT194362 PDGFA Regulation of EGFR 1 0.23 1.56 0
127 INT347296 PDGFA Positive_regulation of CCL16 1 0.06 0.6 0
128 INT196185 Binding of SEMA3A and Nrp1 1 0.01 0.05 0
129 INT286902 Binding of PDGFA and VEGFA 1 0.24 1.1 0
130 INT198002 KDR Negative_regulation of PDGFA 1 0.09 0.94 0
131 INT193307 Binding of PDGFA and PRNP 1 0.01 0 0
132 INT221638 Binding of Nrp1 and Sema3a 1 0.05 0.38 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative chemotaxis. They are ordered first by their pain relevance and then by number of times they were reported in negative chemotaxis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT96775 Gene_expression of Pdgfa 42 0.54 29.78 15.46
2 INT95117 Gene_expression of PDGFA 71 0.71 51.17 6.9
3 INT96778 Positive_regulation of Pdgfa 22 0.46 12.7 5.31
4 INT32256 Gene_expression of PLXNA3 11 0.75 7.8 4.92
5 INT153189 Gene_expression of Sema3a 19 0.75 14.37 4.21
6 INT96776 Positive_regulation of Gene_expression of Pdgfa 8 0.40 7.79 3.93
7 INT52184 Gene_expression of Sema3a 8 0.55 3.97 3.72
8 INT96777 Localization of Pdgfa 12 0.79 5.86 3.52
9 INT21156 Binding of PLXNA3 21 0.36 7.95 3.3
10 INT22375 Localization of PDGFA 21 0.75 15.46 3.25
11 INT271599 Phosphorylation of Pdgfa 1 0.11 2.55 2.81
12 INT172963 Negative_regulation of Pdgfa 11 0.21 12.94 2.64
13 INT15540 Positive_regulation of PDGFA 24 0.47 19.01 2.5
14 INT82347 Regulation of PLXNA3 5 0.60 4.59 2.45
15 INT223080 Binding of Pdgfa 8 0.18 7.21 2.44
16 INT36338 Gene_expression of NRP2 29 0.67 6.47 2.4
17 INT196176 Gene_expression of SEMA3A 3 0.75 4.75 2.17
18 INT64609 Negative_regulation of PLXNA3 5 0.57 3.64 1.94
19 INT153190 Negative_regulation of Sema3a 7 0.56 7.94 1.76
20 INT196158 Binding of NRP2 16 0.06 7.03 1.73
21 INT16622 Positive_regulation of PLXNA3 6 0.67 5.2 1.69
22 INT153762 Positive_regulation of Gene_expression of Sema3a 6 0.49 4.56 1.65
23 INT174107 Binding of Plxna3 4 0.21 2.95 1.62
24 INT146511 Gene_expression of Nrp2 25 0.78 8.67 1.55
25 INT72647 Positive_regulation of Gene_expression of Sema3a 3 0.40 1.98 1.52
26 INT95116 Negative_regulation of PDGFA 24 0.57 19.56 1.29
27 INT150074 Gene_expression of WNT5A 8 0.75 6.3 1.17
28 INT210392 Regulation of PDGFA 10 0.36 11.41 1.12
29 INT96774 Positive_regulation of Localization of Pdgfa 3 0.69 1.21 0.95
30 INT104079 Gene_expression of Plxna3 4 0.65 0.86 0.94
31 INT188317 Positive_regulation of Gene_expression of PDGFA 15 0.46 12.7 0.91
32 INT271598 Negative_regulation of Phosphorylation of Pdgfa 1 0.05 0.77 0.88
33 INT271597 Regulation of Gene_expression of Pdgfa 1 0.05 0.81 0.87
34 INT196182 Localization of NRP2 9 0.46 3.61 0.8
35 INT62760 Localization of PLXNA3 3 0.78 2.06 0.8
36 INT171096 Transcription of PDGFA 5 0.47 4.42 0.79
37 INT95118 Negative_regulation of Gene_expression of PDGFA 4 0.54 5.03 0.76
38 INT104078 Localization of Plxna3 1 0.78 0.36 0.64
39 INT210390 Binding of PDGFA 12 0.36 6.78 0.63
40 INT116175 Negative_regulation of Gene_expression of Sema3a 1 0.30 0.67 0.63
41 INT89067 Regulation of Gene_expression of Sema3a 2 0.31 0.84 0.61
42 INT150075 Positive_regulation of Gene_expression of WNT5A 2 0.67 2.53 0.59
43 INT134304 Positive_regulation of Sema3a 1 0.50 1.23 0.59
44 INT72648 Localization of Sema3a 1 0.28 0.38 0.58
45 INT158486 Negative_regulation of Gene_expression of Sema3a 4 0.41 2.49 0.57
46 INT311943 Negative_regulation of Gene_expression of SEMA3A 1 0.56 0.66 0.55
47 INT72646 Binding of Sema3a 2 0.15 0.52 0.54
48 INT221545 Binding of Sema3a 2 0.33 1.4 0.53
49 INT11847 Regulation of Plxna3 3 0.44 0.45 0.52
50 INT198048 Protein_catabolism of PDGFA 2 0.28 2.05 0.5
51 INT224442 Negative_regulation of Gene_expression of Pdgfa 2 0.30 2.48 0.5
52 INT97962 Negative_regulation of NRP2 2 0.08 0.91 0.5
53 INT343801 Negative_regulation of Transcription of PDGFA 1 0.29 0.37 0.5
54 INT112379 Positive_regulation of Gene_expression of NRP2 3 0.50 0.18 0.46
55 INT135986 Negative_regulation of Sema3a 3 0.58 0.3 0.46
56 INT135987 Regulation of Sema3a 2 0.60 0.57 0.43
57 INT213530 Regulation of Sema3a 3 0.29 0.84 0.42
58 INT46873 Positive_regulation of Plxna3 1 0.49 0 0.38
59 INT213538 Localization of Sema3a 2 0.56 1.12 0.32
60 INT104082 Negative_regulation of Plxna3 1 0.41 0.19 0.32
61 INT104084 Negative_regulation of Localization of Plxna3 1 0.57 0.19 0.32
62 INT221527 Positive_regulation of Sema3a 1 0.37 1.03 0.32
63 INT104080 Regulation of Localization of Plxna3 1 0.60 0.17 0.32
64 INT104083 Negative_regulation of Gene_expression of Plxna3 1 0.42 0.19 0.32
65 INT332231 Positive_regulation of Positive_regulation of Pdgfa 1 0.16 0.83 0.31
66 INT221579 Phosphorylation of Sema3a 1 0.46 0.82 0.3
67 INT192346 Positive_regulation of Localization of PDGFA 5 0.37 1.52 0.29
68 INT158730 Gene_expression of Plxna3 4 0.65 1.82 0.29
69 INT158728 Regulation of Gene_expression of Plxna3 1 0.44 0.28 0.29
70 INT158731 Positive_regulation of Gene_expression of Plxna3 1 0.49 0.28 0.29
71 INT333364 Negative_regulation of Positive_regulation of Pdgfa 1 0.03 0.99 0.22
72 INT302039 Negative_regulation of Nrp2 6 0.51 1.65 0.19
73 INT227947 Regulation of Plxna3 1 0.07 0.2 0.19
74 INT347525 Positive_regulation of Nrp2 1 0.50 0.81 0.18
75 INT332238 Regulation of Regulation of Pdgfa 1 0.14 0.94 0.16
76 INT205603 Regulation of Pdgfa 5 0.16 4.84 0.15
77 INT155694 Phosphorylation of PDGFA 2 0.58 0.42 0.13
78 INT210396 Negative_regulation of Binding of PDGFA 1 0.02 1.6 0.13
79 INT278037 Positive_regulation of Transcription of PDGFA 4 0.07 2.39 0.12
80 INT189625 Binding of SLIT2 3 0.33 0.49 0.12
81 INT203612 Positive_regulation of NRP2 2 0.33 0.49 0.12
82 INT89068 Transcription of Sema3a 1 0.14 0.27 0.11
83 INT162574 Gene_expression of Wnt5a 7 0.47 0.92 0.1
84 INT302043 Negative_regulation of Gene_expression of Nrp2 5 0.59 1.53 0.1
85 INT282594 Localization of WNT5A 2 0.18 0.89 0.1
86 INT221552 Positive_regulation of Localization of Sema3a 1 0.32 0.29 0.1
87 INT233483 Regulation of Gene_expression of Wnt5a 1 0.19 0.33 0.1
88 INT162576 Positive_regulation of Wnt5a 3 0.48 0.71 0.08
89 INT196181 Binding of SEMA3A 2 0.36 0.64 0.07
90 INT290078 Regulation of WNT5A 1 0.07 2.3 0.07
91 INT347526 Regulation of Gene_expression of Nrp2 1 0.62 0.65 0.07
92 INT196164 Localization of SEMA3A 5 0.77 1.39 0.06
93 INT311940 Negative_regulation of SEMA3A 1 0.56 0.71 0.06
94 INT286904 Regulation of Binding of PDGFA 1 0.30 0.74 0.04
95 INT302038 Positive_regulation of Gene_expression of Nrp2 3 0.50 1.12 0.03
96 INT196179 Regulation of Gene_expression of SEMA3A 3 0.43 0.45 0
97 INT302040 Transcription of Nrp2 2 0.53 0.05 0
98 INT353172 Negative_regulation of Plxna3 1 0.01 0.14 0
99 INT347529 Negative_regulation of Transcription of Nrp2 1 0.43 0 0
100 INT196157 Regulation of NRP2 1 0.00 0.16 0
101 INT196170 Regulation of Gene_expression of NRP2 1 0.00 0.16 0
102 INT213595 Localization of SLIT2 1 0.67 0.06 0
103 INT292120 Regulation of Regulation of PDGFA 1 0.12 0.93 0
104 INT213593 Gene_expression of SLIT2 1 0.60 0 0
105 INT335880 Regulation of Wnt5a 1 0.32 0.07 0
106 INT311924 Transcription of Plxna3 1 0.10 0 0
107 INT347305 Negative_regulation of Positive_regulation of PDGFA 1 0.17 0.56 0
108 INT311941 Transcription of SEMA3A 1 0.66 0.34 0
109 INT311933 Regulation of SEMA3A 1 0.43 0.33 0
110 INT302037 Regulation of Nrp2 1 0.18 0.26 0
111 INT196167 Positive_regulation of Gene_expression of SEMA3A 1 0.22 0.06 0
112 INT311944 Negative_regulation of Gene_expression of NRP2 1 0.39 0.17 0
113 INT311938 Regulation of Transcription of SEMA3A 1 0.43 0.34 0
114 INT296201 Binding of Plxna3 1 0.36 0.08 0
115 INT162572 Positive_regulation of Gene_expression of Wnt5a 1 0.02 0.3 0
116 INT188898 Negative_regulation of Localization of PLXNA3 1 0.09 0.47 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox