GO:0050920

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Name regulation of chemotaxis
Categary Process
Go Slim No
Go Link GO:0050920
Unique Molecular Interactions 135
Total Molecular Interactions 262
Total Single Events 1212
Pain Genes Associated 9

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for regulation of chemotaxis. They are ordered first by their pain relevance and then by number of times they were reported for regulation of chemotaxis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT254001 Binding of Cxcr4 and Mif 1 0.52 14.17 7.18
2 INT121651 Binding of CXCL12 and CXCR4 13 0.48 17.61 3.52
3 INT166134 Binding of Cxcl12 and Cxcr4 3 0.49 5.69 3.17
4 INT249483 Binding of Ephb1 and Efnb2 1 0.02 2.35 1.66
5 INT249481 Positive_regulation of Binding of Ephb1 and Efnb2 1 0.03 1.36 1.12
6 INT346835 Gene_expression of Efnb2 Positive_regulation of Phosphorylation of Grin2b 1 0.27 1.07 1.03
7 INT275409 Binding of ITIH4 and Cxcr4 1 0.09 2.87 0.97
8 INT275386 Binding of Cxcr4 and Htatsf1 1 0.01 3.25 0.97
9 INT182190 Binding of IL8 and CXCR4 1 0.26 1.25 0.95
10 INT182210 Binding of CXCR4 and CXCL13 1 0.32 1.25 0.95
11 INT182205 Binding of CXCL5 and CXCR4 1 0.29 1.24 0.94
12 INT182195 Binding of CXCL1 and CXCR4 1 0.13 1.25 0.94
13 INT166135 Regulation of Binding of Cxcl12 and Cxcr4 1 0.30 0.9 0.91
14 INT249491 Efnb2 Positive_regulation of Phosphorylation of Src 1 0.01 0.5 0.87
15 INT254004 Cxcl12 Positive_regulation of Cxcr4 1 0.47 1.29 0.86
16 INT149558 Tgfb1 Positive_regulation of Gene_expression of Cxcr4 1 0.00 0 0.82
17 INT182201 Binding of CXCR5 and CXCR4 1 0.36 1.15 0.72
18 INT182202 Binding of CXCR2 and CXCR4 1 0.31 1.15 0.72
19 INT239538 Binding of CXCR4 and CALCRL 1 0.00 0.35 0.71
20 INT254352 Binding of CXCR4 and Positive_regulation of Gene_expression of CXCL12 1 0.14 1.8 0.66
21 INT344387 Efnb2 Positive_regulation of Phosphorylation of Tyr 1 0.01 1.05 0.66
22 INT249497 Efnb2 Positive_regulation of Phosphorylation of Grin2b 1 0.02 0.51 0.54
23 INT249499 Ephb1 Positive_regulation of Efnb2 1 0.04 0.95 0.54
24 INT275388 Binding of Lamp1 and Cxcr4 1 0.01 1.45 0.52
25 INT275403 Binding of Cxcr4 and GOLPH3 1 0.00 1.45 0.52
26 INT249536 Binding of EPHA1 and Efnb2 1 0.02 0.28 0.52
27 INT275399 Binding of ERVW-1 and Cxcr4 1 0.00 1.73 0.46
28 INT281126 Binding of Ccr2 and Cxcr4 1 0.30 0.32 0.44
29 INT253996 Binding of Cxcr2 and Cxcr4 1 0.18 0.81 0.44
30 INT281154 ITIH4 Positive_regulation of Cxcr4 1 0.09 0.71 0.37
31 INT117184 GOLPH3 Regulation of CXCR4 1 0.30 0.29 0.37
32 INT281123 Binding of Cd4 and Cxcr4 1 0.24 0.92 0.37
33 INT281128 Cd4 Positive_regulation of Cxcr4 1 0.25 0.71 0.37
34 INT117182 GOLPH3 Regulation of Binding of CXCR4 1 0.50 0.29 0.37
35 INT353362 amd Negative_regulation of Cxcr4 1 0.04 0.52 0.33
36 INT226716 Binding of Cxcr4 and Sdf2l1 2 0.30 1.42 0.32
37 INT337085 Binding of Cxcr4 and Mif 1 0.21 1.89 0.3
38 INT281127 Tcf21 Positive_regulation of Gene_expression of Cxcr4 1 0.08 0.42 0.3
39 INT333246 Binding of Cxcr4 and Cxcl12 3 0.34 0.99 0.27
40 INT254000 Regulation of Binding of Cxcr4 and Mif 1 0.29 0.56 0.27
41 INT245072 PPARA Regulation of Gene_expression of CXCR4 1 0.07 0.68 0.26
42 INT281133 Binding of Ccl2 and Cxcr4 1 0.06 0.63 0.24
43 INT88310 ITIH4 Positive_regulation of CXCR4 2 0.27 1.98 0.23
44 INT253991 Negative_regulation of Binding of Cxcl12 and Cxcr4 1 0.43 0.41 0.21
45 INT280270 Tgfb1 Positive_regulation of Gene_expression of Cxcr4 1 0.08 1.81 0.19
46 INT193787 Positive_regulation of CXCR4 Positive_regulation of Positive_regulation of TP53 1 0.03 0.71 0.19
47 INT280267 Tgfb1 Positive_regulation of Cxcr4 1 0.11 2.45 0.19
48 INT226759 Serpinf1 Negative_regulation of Cxcr4 1 0.01 0.58 0.17
49 INT353361 Positive_regulation of Binding of Cxcr4 and Cxcl12 1 0.46 0 0.17
50 INT117183 Binding of CXCR4 and GOLPH3 1 0.53 0.27 0.16
51 INT117191 Binding of CXCR4 and Coro1a 1 0.39 0.28 0.16
52 INT193779 Positive_regulation of ITIH4 Positive_regulation of CXCR4 1 0.19 0.83 0.15
53 INT350713 MIR219-1 Negative_regulation of Pdgfra 1 0.00 0.4 0.15
54 INT226712 Sdf2l1 Positive_regulation of Negative_regulation of Cxcr4 1 0.02 1.34 0.13
55 INT291349 CXCR4 Positive_regulation of EPHB2 1 0.42 1.87 0.13
56 INT182477 Binding of Akt1 and Cxcr4 1 0.10 0.12 0.13
57 INT326380 Binding of Cxcr4 and Podxl 1 0.05 0.36 0.12
58 INT284218 Binding of Cxcr4 and Avpr1b 1 0.00 0.46 0.12
59 INT249495 Binding of Grin2b and Efnb2 1 0.02 0.05 0.11
60 INT294441 KLK4 Negative_regulation of CXCR4 1 0.01 0 0.1
61 INT182644 Binding of CXCR4 and Cxcr4 1 0.10 0.66 0.09
62 INT273655 Binding of FUT1 and Cxcr4 1 0.07 0.41 0.09
63 INT249968 Cxcr4 Positive_regulation of Cxcl12 1 0.17 0.55 0.08
64 INT226746 Cxcr4 Regulation of Protein_catabolism of Vps28 1 0.08 0.35 0.07
65 INT226729 Cxcr4 Regulation of Vps28 1 0.08 0.35 0.07
66 INT226763 Binding of Cxcr4 and Vps28 1 0.07 0.35 0.07
67 INT273653 Cxcr4 Negative_regulation of Binding of FUT1 1 0.08 0.21 0.06
68 INT320402 Binding of Usp14 and Psmb10 1 0.00 0 0.05
69 INT332795 Negative_regulation of Vhl Positive_regulation of Positive_regulation of Cxcr4 1 0.02 1.64 0.05
70 INT241752 ITIH4 Negative_regulation of Binding of CXCR4 1 0.08 0.71 0.04
71 INT263431 Trib3 Regulation of Pdgfra 1 0.00 0 0.04
72 INT263428 Abl1 Regulation of Pdgfra 1 0.00 0 0.04
73 INT245076 CXCR4 Regulation of Gene_expression of VEGFA 1 0.16 1.05 0.03
74 INT183769 Csf2 Negative_regulation of Transcription of CXCR4 1 0.48 0.92 0.03
75 INT183757 INCENP Negative_regulation of Transcription of CXCR4 1 0.01 0.93 0.03
76 INT291357 CXCR4 Positive_regulation of AKT1 1 0.08 1.27 0.03
77 INT121650 Negative_regulation of Binding of CXCL12 and CXCR4 2 0.47 1.61 0
78 INT226728 Tnip1 Regulation of Cxcr4 1 0.04 0.66 0
79 INT245078 FGF2 Positive_regulation of CXCR4 1 0.07 1.36 0
80 INT280262 Binding of Tgfb1 and Positive_regulation of Cxcr4 1 0.07 1.27 0
81 INT226722 Cxcr4 Positive_regulation of Protein_catabolism of Sdf2l1 1 0.02 0.3 0
82 INT245073 VEGFA Positive_regulation of CXCR4 1 0.27 5.09 0
83 INT245074 Gene_expression of VHL Negative_regulation of Gene_expression of CXCR4 1 0.31 1.84 0
84 INT273652 Cxcr4 Regulation of Binding of FUT1 1 0.08 0.22 0
85 INT226739 Tsg101 Regulation of Negative_regulation of Cxcr4 1 0.13 0.69 0
86 INT226762 Gene_expression of Hivan1 Positive_regulation of Cxcr4 1 0.01 0.25 0
87 INT280265 Binding of Cxcr4 and Tgfb1 1 0.06 0.89 0
88 INT226743 Binding of Cxcr4 and Hivan1 1 0.01 1.03 0
89 INT226710 Binding of Cxcr4 and Mela 1 0.02 1.03 0
90 INT226747 Mela Positive_regulation of Gene_expression of Cxcr4 1 0.03 1.01 0
91 INT253993 Positive_regulation of Binding of Cxcr4 and Mif 1 0.50 0 0
92 INT280272 VEGFA Regulation of Cxcr4 1 0.05 0.87 0
93 INT226755 Cxcr4 Negative_regulation of Cd4 1 0.15 0.38 0
94 INT280269 Tgfb1 Regulation of Cxcr4 1 0.04 0.88 0
95 INT226753 Hivan1 Positive_regulation of Negative_regulation of Cxcr4 1 0.01 0.81 0
96 INT226718 Sdf2l1 Negative_regulation of Cxcr4 1 0.02 0.62 0
97 INT226723 Sdf2l1 Positive_regulation of Protein_catabolism of Cxcr4 1 0.03 1.93 0
98 INT280264 Negative_regulation of Binding of Cxcr4 and Tgfb1 1 0.07 0.89 0
99 INT226754 Mela Regulation of Cxcr4 1 0.02 0.66 0
100 INT226730 Tnip1 Positive_regulation of Negative_regulation of Cxcr4 1 0.06 0.81 0
101 INT139619 Binding of Usp14 and Gm16381 1 0.04 1.01 0
102 INT214885 Binding of PDGFRA and Atcay 1 0.08 4.05 0
103 INT336169 Binding of HIVEP1 and CXCR4 1 0.01 0.44 0
104 INT353129 Binding of CD4 and CXCR4 1 0.13 1.08 0
105 INT347957 Binding of PTPRC and Cxcr4 1 0.39 0.37 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for regulation of chemotaxis. They are ordered first by their pain relevance and then by number of times they were reported in regulation of chemotaxis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT88318 Gene_expression of CXCR4 208 0.77 189.67 31.72
2 INT96741 Gene_expression of Cxcr4 62 0.78 32.3 22.14
3 INT256282 Gene_expression of Efnb2 3 0.76 17.61 16.41
4 INT149069 Positive_regulation of Cxcr4 24 0.68 12.21 9.54
5 INT117186 Positive_regulation of CXCR4 29 0.69 24.19 6.84
6 INT126481 Gene_expression of Cxcr4 69 0.77 34.99 6
7 INT253974 Binding of Cxcr4 22 0.47 12.26 5.95
8 INT117189 Binding of CXCR4 34 0.37 24.27 5.81
9 INT96744 Positive_regulation of Gene_expression of Cxcr4 14 0.68 7.92 5.75
10 INT113112 Negative_regulation of CXCR4 39 0.58 28.28 5.36
11 INT346828 Regulation of Efnb2 1 0.61 8.57 3.81
12 INT346826 Positive_regulation of Gene_expression of Efnb2 1 0.46 3.88 3.71
13 INT96740 Transcription of Cxcr4 6 0.68 2.96 3.12
14 INT103674 Positive_regulation of Gene_expression of CXCR4 32 0.69 37.1 3.08
15 INT346829 Negative_regulation of Efnb2 1 0.42 5.08 2.94
16 INT145187 Gene_expression of Efnb2 4 0.22 3.43 2.92
17 INT248177 Localization of Cxcr4 17 0.79 4.87 2.82
18 INT232510 Negative_regulation of Gene_expression of CXCR4 18 0.58 20.27 2.54
19 INT193319 Positive_regulation of Efnb2 2 0.49 2.1 2.47
20 INT346831 Regulation of Gene_expression of Efnb2 1 0.44 2.83 2.47
21 INT149068 Regulation of Cxcr4 3 0.44 3.77 2.46
22 INT110231 Regulation of Gene_expression of Cxcr4 7 0.44 3.18 2.44
23 INT346834 Phosphorylation of Efnb2 1 0.62 1.54 2.19
24 INT126060 Negative_regulation of Gene_expression of Cxcr4 9 0.42 3.14 1.99
25 INT226637 Negative_regulation of Cxcr4 41 0.48 24.42 1.91
26 INT126476 Positive_regulation of Cxcr4 25 0.69 19.01 1.72
27 INT145184 Positive_regulation of Gene_expression of Efnb2 3 0.20 1.94 1.69
28 INT182629 Binding of Cxcr4 12 0.36 5.24 1.47
29 INT113111 Regulation of CXCR4 14 0.61 12.81 1.39
30 INT145183 Negative_regulation of Gene_expression of Efnb2 2 0.17 1.51 1.31
31 INT193815 Regulation of Gene_expression of CXCR4 17 0.61 20.27 1.15
32 INT346832 Negative_regulation of Gene_expression of Efnb2 1 0.42 0.75 1.09
33 INT149553 Negative_regulation of Transcription of Cxcr4 2 0.36 0.29 1.06
34 INT253976 Positive_regulation of Positive_regulation of Cxcr4 1 0.46 1.19 0.96
35 INT182211 Transcription of CXCR4 5 0.69 3.8 0.95
36 INT346827 Binding of Efnb2 1 0.37 1.56 0.91
37 INT226691 Positive_regulation of Gene_expression of Cxcr4 14 0.57 7.9 0.9
38 INT149552 Negative_regulation of Positive_regulation of Cxcr4 1 0.09 0 0.88
39 INT249508 Phosphorylation of Efnb2 1 0.04 0.5 0.84
40 INT119102 Gene_expression of PDGFRA 13 0.75 11.99 0.81
41 INT167677 Localization of Cxcr4 8 0.58 6.61 0.76
42 INT249518 Binding of Efnb2 1 0.02 0.59 0.63
43 INT193811 Localization of CXCR4 6 0.75 7.68 0.58
44 INT346830 Localization of Efnb2 1 0.69 0.47 0.53
45 INT249517 Positive_regulation of Phosphorylation of Efnb2 1 0.03 0.31 0.5
46 INT281150 Regulation of Binding of Cxcr4 1 0.38 0.86 0.46
47 INT346833 Negative_regulation of Binding of Efnb2 1 0.42 0.6 0.45
48 INT253984 Phosphorylation of Cxcr4 2 0.80 0.65 0.43
49 INT193814 Positive_regulation of Positive_regulation of CXCR4 2 0.38 3.08 0.39
50 INT287286 Positive_regulation of Binding of CXCR4 2 0.53 0.78 0.39
51 INT281143 Positive_regulation of Phosphorylation of Cxcr4 1 0.42 0.49 0.36
52 INT126479 Regulation of Cxcr4 11 0.58 10.75 0.34
53 INT226649 Positive_regulation of Positive_regulation of Cxcr4 4 0.39 3.83 0.32
54 INT145190 Positive_regulation of Efnb2 2 0.20 0.18 0.32
55 INT226647 Negative_regulation of Gene_expression of Cxcr4 4 0.40 3.31 0.31
56 INT156411 Gene_expression of Pdgfra 8 0.75 5.5 0.3
57 INT249515 Regulation of Phosphorylation of Efnb2 1 0.01 0.2 0.29
58 INT156410 Positive_regulation of Pdgfra 3 0.08 1.51 0.25
59 INT253973 Positive_regulation of Binding of Cxcr4 1 0.49 0.83 0.24
60 INT245085 Positive_regulation of Negative_regulation of CXCR4 1 0.47 1.7 0.23
61 INT159231 Positive_regulation of PDGFRA 3 0.47 2.39 0.18
62 INT253978 Negative_regulation of Cxcr4 2 0.42 0.61 0.18
63 INT151741 Regulation of PDGFRA 2 0.44 0.78 0.16
64 INT273642 Negative_regulation of Binding of Cxcr4 2 0.35 0.35 0.13
65 INT226668 Positive_regulation of Negative_regulation of Cxcr4 1 0.29 2.77 0.13
66 INT253971 Protein_catabolism of Cxcr4 1 0.98 0.62 0.12
67 INT226639 Phosphorylation of Cxcr4 1 0.47 0.64 0.1
68 INT136182 Negative_regulation of PDGFRA 3 0.43 2.43 0.08
69 INT226634 Protein_catabolism of Cxcr4 1 0.57 6.83 0.08
70 INT232713 Binding of PDGFRA 1 0.35 1.43 0.08
71 INT139614 Gene_expression of Usp14 1 0.78 2.29 0.06
72 INT253985 Regulation of Localization of Cxcr4 1 0.44 0.26 0.06
73 INT320416 Binding of Usp14 1 0.23 0 0.05
74 INT183764 Negative_regulation of Transcription of CXCR4 1 0.41 0.91 0.03
75 INT245080 Regulation of Negative_regulation of CXCR4 1 0.45 0.78 0.03
76 INT165212 Regulation of Gene_expression of Cxcr4 4 0.48 1.33 0
77 INT226677 Regulation of Negative_regulation of Cxcr4 3 0.25 2.54 0
78 INT226654 Negative_regulation of Negative_regulation of Cxcr4 1 0.34 3.39 0
79 INT280237 Negative_regulation of Positive_regulation of Cxcr4 1 0.33 0.75 0
80 INT347956 Negative_regulation of Regulation of Cxcr4 1 0.40 1.25 0
81 INT352608 Binding of Pdgfra 1 0.27 0.7 0
82 INT295427 Localization of PDGFRA 1 0.40 1.04 0
83 INT226662 Negative_regulation of Protein_catabolism of Cxcr4 1 0.25 0.37 0
84 INT226701 Transcription of Cxcr4 1 0.40 0 0
85 INT352609 Positive_regulation of Gene_expression of Pdgfra 1 0.58 1.18 0
86 INT139615 Binding of Usp14 1 0.48 0.99 0
87 INT226686 Regulation of Positive_regulation of Cxcr4 1 0.26 0.46 0
88 INT200836 Transcription of Pdgfra 1 0.30 0.26 0
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