GO:0050965

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Name detection of temperature stimulus involved in sensory perception of pain
Categary Process
Go Slim No
Go Link GO:0050965
Unique Molecular Interactions 926
Total Molecular Interactions 1415
Total Single Events 21756
Pain Genes Associated 17

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for detection of temperature stimulus involved in sensory perception of pain. They are ordered first by their pain relevance and then by number of times they were reported for detection of temperature stimulus involved in sensory perception of pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT69886 Ngf Positive_regulation of Calca 8 0.76 2.98 12.77
2 INT166591 Binding of CALCA and DCLK3 4 0.30 0.69 12.18
3 INT77646 Binding of Ngf and Ntrk1 23 0.40 7.85 9.26
4 INT180785 Gdnf Positive_regulation of Calca 1 0.23 1.96 8.04
5 INT142177 Calca Positive_regulation of Gene_expression of Igf1 8 0.78 3.57 5.71
6 INT88279 Ngf Positive_regulation of Ntrk1 5 0.76 3.06 5.23
7 INT69888 Ngf Positive_regulation of Localization of Calca 4 0.52 0.51 4.95
8 INT102122 Binding of Calca and RT1-M4 7 0.29 5.83 4.94
9 INT11599 Calca Positive_regulation of Npr1 5 0.19 0.3 4.8
10 INT24742 Binding of Calca and Vip 1 0.37 0.18 4.68
11 INT128998 Cxcl1 Positive_regulation of Localization of Calca 1 0.66 2.96 4.15
12 INT13969 Binding of Calca and Sst 3 0.32 0.6 4.02
13 INT82023 Binding of Ntrk1 and Ngf 5 0.53 3.48 3.92
14 INT13966 Calca Positive_regulation of Localization of Sst 5 0.49 0.75 3.91
15 INT85541 Ngf Positive_regulation of Gene_expression of Calca 2 0.55 1.84 3.71
16 INT87491 CALCA Positive_regulation of Gene_expression of IL8 1 0.72 0.92 3.52
17 INT24710 Binding of Calca and SUB1P1 1 0.01 2.09 3.48
18 INT108471 Binding of CALCA and PNOC 1 0.29 0.64 3.25
19 INT354207 Igfbp7 Positive_regulation of Accn3 1 0.52 6.55 3.24
20 INT74159 Ngf Regulation of Gene_expression of Calca 2 0.60 1.66 3.22
21 INT29657 Binding of Calca and Calcb 1 0.26 0 3.16
22 INT106837 Binding of Oprm1 and Arrb2 3 0.32 0.83 3.01
23 INT37162 Binding of Calca and Cckar 1 0.04 0.55 3.01
24 INT100835 Binding of Calca and Akap12 1 0.07 0.41 2.92
25 INT166592 Binding of CALCA and RAMP1 2 0.35 0.33 2.91
26 INT73821 CALCA Positive_regulation of Localization of IL8 1 0.25 2.37 2.91
27 INT221746 Ngf Positive_regulation of Ntrk1 1 0.02 0.92 2.88
28 INT194409 Binding of CALCA and IGKV1D-8 1 0.15 0 2.84
29 INT169134 Binding of Calca and Trpa1 1 0.37 3.37 2.79
30 INT180779 Bdnf Regulation of Calca 1 0.09 0.23 2.71
31 INT92738 Binding of Ephb1 and Tcas1 1 0.00 0.43 2.67
32 INT53648 Acot1 Positive_regulation of Localization of Calca 2 0.23 0 2.61
33 INT121742 Prkcg Positive_regulation of Ephb1 3 0.49 0.99 2.6
34 INT128044 Bdnf Positive_regulation of Ephb1 2 0.31 1.89 2.57
35 INT57624 Calca Regulation of Positive_regulation of Trh 1 0.50 0 2.53
36 INT48526 Binding of Calca and Penk 1 0.24 1.03 2.51
37 INT136129 Calca Positive_regulation of ATP8A2 1 0.38 0.89 2.4
38 INT121746 Prkaca Positive_regulation of Ephb1 2 0.23 0.92 2.35
39 INT13967 Calca Positive_regulation of Sst 1 0.45 0 2.3
40 INT152900 TRPV1 Regulation of Gene_expression of CALCA 1 0.69 0.73 2.29
41 INT152901 TRPV1 Regulation of Localization of CALCA 1 0.44 0.73 2.29
42 INT156623 Umod Regulation of Phosphorylation of Ephb1 1 0.05 0.33 2.27
43 INT69887 Ngf Regulation of Calca 2 0.49 0.1 2.19
44 INT134583 Arrb2 Regulation of Oprm1 1 0.41 1.23 2.15
45 INT79470 Mgat4a Regulation of Localization of Calca 1 0.08 1.72 2.1
46 INT89733 Binding of Calca and Nrm 1 0.31 0.71 2.09
47 INT63873 SRPX Positive_regulation of Localization of Calca 1 0.02 0.49 2.04
48 INT115042 Gdnf Regulation of Calca 1 0.53 0.25 2.03
49 INT26221 Calca Regulation of Gt(pU21)50Imeg 1 0.01 0 2.02
50 INT128996 Ccl2 Positive_regulation of Localization of Calca 1 0.68 1.43 2
51 INT213968 Binding of Calca and Mthfd1 1 0.05 0.16 1.99
52 INT153533 NMS Regulation of Gene_expression of Ephb1 1 0.48 3.96 1.93
53 INT120723 Positive_regulation of Trpv1 Positive_regulation of Localization of Calca 3 0.51 0.48 1.92
54 INT83418 Binding of OPRL1 and Ntrk1 1 0.02 0 1.91
55 INT95405 Trib3 Positive_regulation of Phosphorylation of Ephb1 3 0.08 1.33 1.89
56 INT24942 Calca Regulation of TAC1 1 0.13 0.7 1.89
57 INT271408 NGF Positive_regulation of Gene_expression of CALCA 1 0.09 4.89 1.88
58 INT112517 Binding of Ephb1 and Prkaca 3 0.18 0.58 1.85
59 INT168723 Positive_regulation of Trpv1 Positive_regulation of Gene_expression of Calca 1 0.48 1.1 1.84
60 INT163514 Ngf Positive_regulation of Gene_expression of Calca 1 0.30 2.21 1.82
61 INT121218 Arrb2 Regulation of Negative_regulation of Prkca 1 0.17 0.23 1.8
62 INT162992 Binding of Ephb1 and Ppm1e 1 0.03 0.25 1.77
63 INT24934 Calca Regulation of Nka1 3 0.05 0.43 1.73
64 INT148090 Binding of CALCA and NCOR2 1 0.00 0.65 1.71
65 INT94617 KNG1 Positive_regulation of Localization of Calca 1 0.00 0.75 1.7
66 INT56134 CALCA Positive_regulation of POMC 2 0.71 0.72 1.68
67 INT102447 Binding of CALCA and CALCRL 2 0.26 0.33 1.67
68 INT108385 Binding of Crygs and Ntrk1 1 0.01 0 1.67
69 INT145826 Calca Positive_regulation of Gene_expression of Igf1 3 0.75 3.05 1.66
70 INT249483 Binding of Ephb1 and Efnb2 1 0.02 2.35 1.66
71 INT94618 KNG1 Positive_regulation of Calca 1 0.00 0.75 1.66
72 INT144213 Nppa Positive_regulation of Localization of Calca 1 0.71 2.8 1.65
73 INT23889 Calca Positive_regulation of Localization of Tacr1 1 0.11 0.45 1.65
74 INT24157 Binding of CALCA and SFTPA1 2 0.07 0.96 1.64
75 INT354210 Binding of Igfbp7 and Accn3 1 0.27 3.91 1.64
76 INT122286 Prkaca Negative_regulation of Negative_regulation of Calca 1 0.12 0.54 1.63
77 INT160578 Binding of CALCA and TAC1 1 0.07 0.91 1.61
78 INT131575 Grin1 Negative_regulation of Positive_regulation of Ephb1 1 0.28 0.31 1.58
79 INT131574 Negative_regulation of Ephb1 Negative_regulation of Gene_expression of Creb1 1 0.41 0.33 1.58
80 INT148935 Ramp1 Regulation of Calca 1 0.27 0.69 1.56
81 INT13968 Calca Negative_regulation of Positive_regulation of Sst 1 0.34 0 1.55
82 INT13970 Positive_regulation of Calca Positive_regulation of Sst 1 0.37 0 1.53
83 INT13965 Calca Positive_regulation of Positive_regulation of Sst 1 0.37 0 1.53
84 INT158778 Ptges3l1 Regulation of Ephb1 1 0.06 0.09 1.53
85 INT158775 Regulation of Tnf Regulation of Ephb1 1 0.18 0.09 1.52
86 INT158777 Tnf Regulation of Ephb1 1 0.18 0.09 1.51
87 INT125845 Positive_regulation of Pag1 Positive_regulation of Gene_expression of Arrb2 1 0.09 0.46 1.48
88 INT96784 Binding of CALCA and Calca 3 0.23 0.27 1.47
89 INT180791 Negative_regulation of Gdnf Regulation of Calca 1 0.17 0 1.47
90 INT158776 Il1b Regulation of Ephb1 1 0.15 0.09 1.46
91 INT83416 Binding of OPRK1 and Ntrk1 1 0.02 0 1.45
92 INT180767 Bdnf Positive_regulation of Gene_expression of Calca 1 0.17 0 1.45
93 INT276681 Calca Regulation of Nav1 1 0.07 0.74 1.45
94 INT276686 Calca Regulation of Nav1 1 0.26 0.74 1.45
95 INT84434 Calca Negative_regulation of Negative_regulation of Hrh1 1 0.06 0.19 1.44
96 INT95325 HTR1B Negative_regulation of Calca 1 0.47 0.69 1.43
97 INT256299 Binding of Efnb1 and Ephb1 1 0.02 1.22 1.42
98 INT134760 Ghrl Regulation of Transcription of Calca 1 0.24 2.71 1.42
99 INT144122 Binding of Calca and P2rx6 1 0.10 0 1.4
100 INT169163 Binding of Calca and Ctbs 1 0.00 0.51 1.4
101 INT249494 Binding of Ephb1 and Efnb1 1 0.01 1.34 1.4
102 INT51213 Vip Regulation of Localization of Calca 1 0.38 0 1.39
103 INT8719 Npy Negative_regulation of Localization of Calca 1 0.06 0.26 1.39
104 INT168724 Creb1 Negative_regulation of Gene_expression of Calca 1 0.46 1.09 1.38
105 INT168721 Positive_regulation of Creb1 Positive_regulation of Calca 1 0.53 1.07 1.37
106 INT261483 Binding of Ephb1 and Trpv1 1 0.39 1.37 1.37
107 INT279165 Calca Regulation of Gene_expression of Fdft1 1 0.02 0.41 1.37
108 INT82025 Negative_regulation of Binding of Ntrk1 and Ngf 1 0.47 0.64 1.37
109 INT180810 Gopc Positive_regulation of Calca 1 0.02 0.28 1.36
110 INT83197 Binding of Ntrk1 and Gdnf 1 0.01 1.05 1.36
111 INT168722 Creb1 Positive_regulation of Calca 1 0.73 1.05 1.35
112 INT151771 Binding of P2RX3 and Calca 1 0.04 0.89 1.34
113 INT298455 Calca Positive_regulation of Gene_expression of Ceacam3 1 0.17 0.47 1.34
114 INT106839 Arrb2 Regulation of Oprm1 2 0.21 0.44 1.33
115 INT180786 Calca Regulation of Positive_regulation of Ngf 1 0.40 0 1.32
116 INT136603 Calca Positive_regulation of Localization of Il6 1 0.67 0.78 1.32
117 INT180764 Calca Regulation of Positive_regulation of Gdnf 1 0.21 0 1.32
118 INT180807 Calca Regulation of Sorbs1 1 0.02 0 1.32
119 INT180771 Calca Regulation of Positive_regulation of Bdnf 1 0.18 0 1.32
120 INT121096 Binding of Calca and Trpv1 3 0.37 1.23 1.29
121 INT95406 Trib3 Positive_regulation of Ephb1 2 0.08 0.96 1.29
122 INT148775 Binding of Calca and Usf1 1 0.43 0.85 1.29
123 INT194408 Regulation of Binding of CALCA and DCLK3 1 0.15 0 1.29
124 INT138210 Mzb1 Regulation of Calca 1 0.25 0.41 1.29
125 INT22501 Binding of Calca and Pth 1 0.21 0.07 1.28
126 INT352269 Binding of Jund and Adora1 1 0.15 1.2 1.25
127 INT88635 Ptger3 Positive_regulation of Localization of Calca 2 0.05 0 1.24
128 INT92800 Arrb2 Negative_regulation of Oprm1 1 0.37 0.33 1.24
129 INT249487 Binding of Ephb1 and Src 1 0.17 0.74 1.23
130 INT147033 Positive_regulation of Binding of Sds and Accn3 1 0.13 0.73 1.23
131 INT103031 Calca Positive_regulation of Ptgs1 2 0.46 0.98 1.22
132 INT121729 Negative_regulation of Ngf Positive_regulation of Ephb1 1 0.24 0.69 1.22
133 INT256298 Binding of Creb1 and Ephb1 1 0.16 1.27 1.22
134 INT151454 Binding of Calca and Insrr 1 0.02 0.31 1.22
135 INT147032 Binding of Sds and Accn3 1 0.09 0.73 1.22
136 INT87586 RPL7AP5 Negative_regulation of Gene_expression of Calca 1 0.00 0.05 1.21
137 INT79471 Mgat4a Regulation of Calca 1 0.06 1.09 1.21
138 INT87585 RPL7AP5 Negative_regulation of Calca 1 0.00 0.05 1.21
139 INT121724 Ngf Positive_regulation of Ephb1 1 0.40 0.68 1.21
140 INT124874 Gnat3 Positive_regulation of Localization of Calca 2 0.08 0.75 1.2
141 INT334351 Bdnf Regulation of Positive_regulation of Ephb1 1 0.18 1.27 1.2
142 INT116730 Rac1 Regulation of Localization of Calca 1 0.13 1.32 1.19
143 INT351373 Ngf Positive_regulation of Gene_expression of Ntrk1 1 0.35 0.41 1.18
144 INT194403 Negative_regulation of Binding of CALCA and DCLK3 1 0.22 0 1.18
145 INT351378 Gene_expression of Ngf Positive_regulation of Ntrk1 1 0.35 0.41 1.18
146 INT351377 Gene_expression of Ngf Positive_regulation of Gene_expression of Ntrk1 1 0.35 0.41 1.18
147 INT215648 Binding of Adora1 and Gabrd 1 0.03 0.06 1.16
148 INT338053 F2r Positive_regulation of Localization of Calca 1 0.06 0.47 1.15
149 INT91394 Negative_regulation of MMP2 Positive_regulation of CALCA 1 0.25 0.15 1.15
150 INT256041 Binding of Ngfr and Ntrk1 3 0.14 0.9 1.13
151 INT141979 Calca Negative_regulation of Gene_expression of Il1b 1 0.40 0.62 1.13
152 INT249481 Positive_regulation of Binding of Ephb1 and Efnb2 1 0.03 1.36 1.12
153 INT249488 Positive_regulation of Binding of Ephb1 and Src 1 0.23 0.68 1.12
154 INT269190 Positive_regulation of Ephb1 Positive_regulation of Ceacam3 1 0.03 0.66 1.12
155 INT22176 Calca Regulation of Localization of Prl 4 0.69 0.39 1.11
156 INT4752 Gal Negative_regulation of Localization of Calca 1 0.41 0.06 1.11
157 INT282065 Binding of Calca and Ngf 1 0.14 0.85 1.11
158 INT4753 Sst Negative_regulation of Localization of Calca 1 0.39 0.06 1.1
159 INT70495 CALCA Positive_regulation of CALCB 2 0.40 0 1.08
160 INT352453 Calca Positive_regulation of Trib3 1 0.00 0.8 1.08
161 INT69889 Ngf Regulation of Localization of Calca 1 0.49 0.1 1.08
162 INT352468 Calca Positive_regulation of Prkaca 1 0.11 0.8 1.08
163 INT256294 Binding of Grin2b and Ephb1 1 0.28 1.11 1.08
164 INT91395 MMP2 Positive_regulation of CALCA 1 0.36 0.17 1.07
165 INT79372 Calca Regulation of Pnoc 1 0.34 0 1.07
166 INT156462 Creb1 Regulation of Ephb1 1 0.29 0 1.07
167 INT10238 Binding of EDN1 and Calca 1 0.00 1.07 1.06
168 INT269192 Ephb1 Regulation of Phosphorylation of Grin2a 1 0.02 0.63 1.06
169 INT139225 Calca Negative_regulation of Icam1 1 0.44 1.13 1.06
170 INT121727 Pik3cb Positive_regulation of Ephb1 1 0.49 0.6 1.06
171 INT139229 Calca Negative_regulation of Cmklr1 1 0.19 1.12 1.06
172 INT93614 Ngf Positive_regulation of Ntrk1 2 0.52 0.85 1.05
173 INT139231 Calca Negative_regulation of Timp1 1 0.36 1.11 1.05
174 INT139226 Icam1 Negative_regulation of Calca 1 0.44 1.12 1.05
175 INT146097 Positive_regulation of Binding of Rgs9 and Arrb2 1 0.28 0 1.04
176 INT48260 Binding of Adcyap1 and Calca 1 0.35 0 1.04
177 INT130167 Trpv1 Regulation of Localization of Calca 2 0.38 0.69 1.03
178 INT86073 Med15 Regulation of Calca 1 0.49 0.2 1.03
179 INT114555 Binding of Calca and St3gal3 1 0.01 0.44 1.03
180 INT146098 Binding of Rgs9 and Arrb2 1 0.19 0 1.03
181 INT114552 Binding of Calca and Col4a4 1 0.01 0.44 1.02
182 INT121743 Negative_regulation of Src Negative_regulation of Ephb1 1 0.27 0 1.02
183 INT51260 Calca Negative_regulation of Nts 1 0.10 0.08 1.01
184 INT240455 Ephb1 Positive_regulation of Positive_regulation of Prkaca 1 0.22 0.63 1.01
185 INT51261 Calca Negative_regulation of Sst 1 0.20 0.08 1.01
186 INT298298 Calca Negative_regulation of Gene_expression of Runx1 1 0.19 0.33 1
187 INT143916 Arrb2 Regulation of Rbm39 1 0.04 0.18 1
188 INT112163 Calca Positive_regulation of Mpo 1 0.49 1.23 1
189 INT298274 Gene_expression of Runx1 Negative_regulation of Calca 1 0.19 0.33 1
190 INT162299 Negative_regulation of Adarb1 Negative_regulation of Gene_expression of Calca 1 0.01 0.93 1
191 INT94989 Arrb2 Regulation of Regulation of Oprm1 1 0.24 0 0.98
192 INT49163 Binding of Pax3 and Calca 1 0.03 0.37 0.98
193 INT24395 Binding of CALCA and CLPP 1 0.03 0.17 0.96
194 INT121744 Src Positive_regulation of Positive_regulation of Ephb1 1 0.35 0 0.96
195 INT111632 Arrb2 Negative_regulation of Regulation of Rbm39 1 0.03 0 0.96
196 INT83415 Binding of Oprm1 and Ntrk1 1 0.01 0 0.96
197 INT206857 Binding of Calca and Calcrl 4 0.37 1.9 0.95
198 INT148772 Usf1 Regulation of Calca 1 0.40 0.69 0.95
199 INT354224 Bdnf Positive_regulation of Transcription of Accn3 1 0.09 1.04 0.95
200 INT180787 Calca Regulation of Gdnf 1 0.18 0.28 0.95

Single Events

The table below shows the top 100 pain related interactions that have been reported for detection of temperature stimulus involved in sensory perception of pain. They are ordered first by their pain relevance and then by number of times they were reported in detection of temperature stimulus involved in sensory perception of pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT2542 Localization of Calca 2008 0.81 518.3 1408.65
2 INT1912 Gene_expression of Calca 1152 0.78 453.25 739.84
3 INT2543 Positive_regulation of Calca 787 0.70 331.13 592.08
4 INT4758 Positive_regulation of Localization of Calca 557 0.70 138.55 411.04
5 INT2540 Negative_regulation of Calca 538 0.59 172.11 384.38
6 INT2649 Regulation of Calca 433 0.62 146.05 330.95
7 INT63932 Positive_regulation of Ephb1 537 0.70 259.67 296.14
8 INT4759 Negative_regulation of Localization of Calca 294 0.59 82.62 226.45
9 INT626 Localization of CALCA 289 0.81 125.39 221.15
10 INT63934 Phosphorylation of Ephb1 377 0.82 150.52 188.66
11 INT5050 Regulation of Localization of Calca 149 0.62 41.25 148.57
12 INT3300 Positive_regulation of Gene_expression of Calca 179 0.70 77.76 144.2
13 INT2867 Gene_expression of CALCA 247 0.78 78.78 138.47
14 INT2541 Binding of Calca 200 0.48 67.14 134.62
15 INT5008 Localization of Calca 204 0.81 80.35 125.16
16 INT5010 Gene_expression of Calca 197 0.78 85.76 118.75
17 INT48923 Gene_expression of Ephb1 211 0.77 106.23 109.9
18 INT4860 Positive_regulation of CALCA 148 0.00 73.35 97.61
19 INT5780 Regulation of Gene_expression of Calca 90 0.62 59.52 85.03
20 INT63936 Positive_regulation of Phosphorylation of Ephb1 131 0.70 49.38 73.16
21 INT50971 Gene_expression of Ntrk1 180 0.75 73.52 62.28
22 INT6761 Binding of CALCA 100 0.48 26.71 62.05
23 INT4760 Negative_regulation of Gene_expression of Calca 93 0.59 34.19 60.3
24 INT4241 Regulation of CALCA 87 0.62 28.19 55.29
25 INT84495 Positive_regulation of Positive_regulation of Ephb1 85 0.70 46.12 54.11
26 INT4891 Transcription of Calca 81 0.72 35.27 53.75
27 INT8700 Positive_regulation of Positive_regulation of Calca 56 0.67 21.69 53.66
28 INT97674 Positive_regulation of Localization of Calca 70 0.69 27.71 51.79
29 INT8490 Negative_regulation of CALCA 87 0.59 29.73 51.34
30 INT48920 Negative_regulation of Ephb1 107 0.57 43.6 51.02
31 INT11406 Positive_regulation of Localization of CALCA 49 0.70 20.64 42.8
32 INT48929 Regulation of Ephb1 71 0.62 24.42 42.11
33 INT28265 Positive_regulation of Calca 62 0.70 29.1 41.17
34 INT8784 Negative_regulation of Positive_regulation of Calca 40 0.59 14.67 33.49
35 INT8746 Negative_regulation of Calca 50 0.59 21.22 33.45
36 INT63933 Negative_regulation of Positive_regulation of Ephb1 53 0.58 22.83 33.43
37 INT63935 Positive_regulation of Gene_expression of Ephb1 52 0.61 24.3 33.05
38 INT40160 Positive_regulation of Adora1 74 0.70 26.36 33.03
39 INT23463 Positive_regulation of Gene_expression of CALCA 47 0.70 18.14 28.76
40 INT84494 Negative_regulation of Phosphorylation of Ephb1 44 0.59 22.34 28.68
41 INT98522 Gene_expression of Accn3 68 0.78 26.95 28.6
42 INT22499 Regulation of Calca 42 0.62 17.32 28.02
43 INT123035 Gene_expression of Ephb1 38 0.78 28.84 27.32
44 INT100124 Gene_expression of Accn3 38 0.78 30.02 23.63
45 INT50970 Positive_regulation of Ntrk1 51 0.57 29.38 22.83
46 INT8358 Negative_regulation of Localization of CALCA 25 0.59 11.79 21.51
47 INT56769 Gene_expression of Ntrk1 36 0.77 15.79 20.75
48 INT109379 Regulation of Phosphorylation of Ephb1 22 0.59 12.58 18.84
49 INT92733 Negative_regulation of Ephb1 19 0.51 8.56 17.72
50 INT50972 Negative_regulation of Ntrk1 39 0.51 32.22 17.29
51 INT35998 Positive_regulation of Gene_expression of Calca 31 0.70 16.16 16.98
52 INT6150 Positive_regulation of Negative_regulation of Calca 20 0.68 4.06 16.26
53 INT25872 Positive_regulation of Adora1 19 0.69 4.9 15.01
54 INT128921 Negative_regulation of Gene_expression of Ephb1 18 0.49 9.54 14.93
55 INT115071 Positive_regulation of Accn3 14 0.70 16.56 14.24
56 INT84496 Regulation of Positive_regulation of Ephb1 18 0.61 10.16 13.92
57 INT65109 Negative_regulation of Transcription of Calca 16 0.59 8.63 12.84
58 INT26217 Binding of Calca 22 0.48 5.22 12.57
59 INT11244 Transcription of CALCA 21 0.69 3.61 12.27
60 INT15136 Regulation of Positive_regulation of Calca 12 0.62 3.02 12.16
61 INT6151 Negative_regulation of Negative_regulation of Calca 14 0.58 4.86 11.81
62 INT135909 Positive_regulation of Ephb1 11 0.70 8.94 11.78
63 INT94981 Gene_expression of Arrb2 12 0.70 2.11 11.75
64 INT5779 Positive_regulation of Transcription of Calca 15 0.62 5.61 10.86
65 INT19155 Binding of Adora1 25 0.47 6.41 10.72
66 INT101203 Negative_regulation of Gene_expression of Calca 12 0.59 7.06 10.72
67 INT109578 Positive_regulation of Accn3 16 0.70 9.09 10.05
68 INT114406 Gene_expression of Adora1 28 0.72 6.83 9.13
69 INT108384 Binding of Ntrk1 28 0.39 10.73 9.09
70 INT103251 Negative_regulation of Localization of Calca 13 0.43 9.36 8.86
71 INT8761 Negative_regulation of Binding of Calca 12 0.43 3.59 8.32
72 INT127853 Localization of Ephb1 20 0.74 5.47 7.96
73 INT9350 Regulation of ADORA1 9 0.12 1.53 7.79
74 INT101699 Regulation of Adora1 14 0.61 3.7 7.59
75 INT147715 Regulation of Gene_expression of Ephb1 6 0.62 5.26 7.49
76 INT50973 Negative_regulation of Gene_expression of Ntrk1 22 0.56 11.12 7.38
77 INT25220 Positive_regulation of Binding of Calca 7 0.69 3.78 7.34
78 INT124264 Regulation of Localization of Calca 10 0.33 1.39 7.14
79 INT40159 Negative_regulation of Adora1 13 0.51 3.51 7.13
80 INT92734 Binding of Ephb1 5 0.37 3.86 7.02
81 INT76197 Positive_regulation of ADORA1 7 0.59 5.06 7
82 INT9167 Binding of Adora1 6 0.40 0.53 6.9
83 INT76255 Gene_expression of ADORA1 11 0.78 2.51 6.85
84 INT100079 Positive_regulation of Gene_expression of Arrb2 7 0.63 2.26 6.77
85 INT154773 Regulation of Accn3 7 0.62 7.09 6.63
86 INT136496 Regulation of Accn3 5 0.45 3.72 6.53
87 INT48922 Regulation of Gene_expression of Ephb1 14 0.50 5.73 6.47
88 INT94979 Regulation of Arrb2 6 0.54 0.51 6.45
89 INT129020 Phosphorylation of Ntrk1 17 0.80 5.97 6.37
90 INT79737 Positive_regulation of Ntrk1 12 0.49 3.98 6.24
91 INT94986 Positive_regulation of Arrb2 5 0.61 1.3 6.24
92 INT52813 Regulation of Localization of CALCA 8 0.62 3.16 5.89
93 INT181053 Regulation of Ephb1 6 0.45 6.17 5.77
94 INT109577 Positive_regulation of Gene_expression of Accn3 9 0.67 4.77 5.76
95 INT86982 Transcription of Calca 9 0.69 2.98 5.74
96 INT5778 Regulation of Transcription of Calca 4 0.45 2.47 5.37
97 INT14715 Negative_regulation of Positive_regulation of CALCA 5 0.43 2.22 5.2
98 INT126847 Binding of Ephb1 15 0.46 6.47 5.17
99 INT85685 Gene_expression of Arrb2 5 0.74 0.66 5.13
100 INT27261 Regulation of Regulation of Calca 7 0.45 2.8 5.08
101 INT140799 Positive_regulation of Gene_expression of Accn3 6 0.68 5.44 5.06
102 INT37148 Negative_regulation of Gene_expression of CALCA 7 0.43 1.91 4.98
103 INT85681 Negative_regulation of Arrb2 5 0.47 0.79 4.71
104 INT52251 Negative_regulation of Binding of CALCA 3 0.41 0.57 4.71
105 INT54987 Regulation of Gene_expression of Calca 6 0.62 3.44 4.59
106 INT78981 Regulation of Ntrk1 6 0.44 3.89 4.52
107 INT108935 Transcription of Arrb2 5 0.59 0.5 4.38
108 INT81750 Regulation of Ntrk1 13 0.52 6.03 4.37
109 INT100125 Negative_regulation of Accn3 11 0.59 5.85 4.32
110 INT92797 Regulation of Arrb2 4 0.44 0.81 4.28
111 INT94985 Regulation of Gene_expression of Arrb2 2 0.40 0.43 4.2
112 INT79736 Negative_regulation of Ntrk1 11 0.57 2.31 4.14
113 INT24677 Regulation of Negative_regulation of Calca 6 0.44 0.73 3.9
114 INT56768 Positive_regulation of Gene_expression of Ntrk1 5 0.67 3.91 3.83
115 INT85679 Binding of Arrb2 4 0.39 0.79 3.82
116 INT83411 Binding of Ntrk1 6 0.19 3.7 3.74
117 INT65527 Positive_regulation of Positive_regulation of Adora1 4 0.46 0.67 3.71
118 INT215604 Localization of Adora1 10 0.78 1.47 3.49
119 INT94983 Negative_regulation of Arrb2 2 0.52 0.26 3.47
120 INT72256 Binding of Accn3 6 0.47 2.01 3.2
121 INT51151 Positive_regulation of Regulation of Calca 8 0.50 1.77 3.08
122 INT101477 Binding of ADORA1 8 0.31 0.42 3.07
123 INT85682 Positive_regulation of Arrb2 4 0.46 0.22 3.05
124 INT165084 Transcription of Accn3 3 0.70 3.4 3.01
125 INT276842 Positive_regulation of Transcription of Accn3 2 0.49 3.32 2.93
126 INT27146 Negative_regulation of Regulation of Calca 4 0.43 1.18 2.9
127 INT156189 Positive_regulation of Gene_expression of Ntrk1 11 0.49 2.81 2.89
128 INT54178 Regulation of Adora1 5 0.39 0.29 2.85
129 INT60672 Regulation of Gene_expression of CALCA 3 0.61 1.76 2.85
130 INT95720 Phosphorylation of Calca 2 0.80 2.04 2.8
131 INT57354 Positive_regulation of Positive_regulation of Calca 3 0.60 1.42 2.78
132 INT256286 Negative_regulation of Gene_expression of Ephb1 1 0.43 3.36 2.78
133 INT100126 Localization of Accn3 7 0.77 2.73 2.76
134 INT8840 Positive_regulation of Positive_regulation of CALCA 8 0.50 1.8 2.74
135 INT215608 Negative_regulation of Binding of Adora1 5 0.41 1.35 2.73
136 INT115070 Binding of Accn3 4 0.47 3.8 2.7
137 INT62610 Phosphorylation of Ntrk1 5 0.56 1.64 2.68
138 INT215601 Regulation of Positive_regulation of Adora1 9 0.60 1.74 2.66
139 INT215599 Positive_regulation of Positive_regulation of Adora1 7 0.47 2.29 2.58
140 INT114020 Gene_expression of Adora1 2 0.33 4.24 2.55
141 INT19292 Protein_catabolism of CALCA 7 0.76 0.8 2.53
142 INT108937 Negative_regulation of Transcription of Arrb2 1 0.38 0.31 2.31
143 INT215611 Negative_regulation of Positive_regulation of Adora1 6 0.43 1.18 2.16
144 INT108939 Regulation of Transcription of Arrb2 1 0.24 0.19 2.1
145 INT58752 Positive_regulation of Binding of CALCA 3 0.49 0.73 2.09
146 INT152902 Positive_regulation of Transcription of CALCA 5 0.66 0.99 2.07
147 INT129155 Negative_regulation of Accn3 4 0.46 1.36 2.07
148 INT54986 Negative_regulation of Positive_regulation of Calca 2 0.43 0.93 2.02
149 INT126988 Transcription of Accn3 5 0.61 0.88 2
150 INT24291 Positive_regulation of Negative_regulation of CALCA 3 0.61 0.67 1.91
151 INT32558 Negative_regulation of ADORA1 5 0.12 2.77 1.86
152 INT107477 Positive_regulation of Phosphorylation of Ntrk1 3 0.30 0.88 1.86
153 INT223447 Regulation of Gene_expression of Ntrk1 7 0.34 1.29 1.82
154 INT124556 Negative_regulation of Positive_regulation of Adora1 3 0.51 1.2 1.81
155 INT168519 Positive_regulation of Gene_expression of Adora1 4 0.61 0.75 1.75
156 INT125844 Positive_regulation of Gene_expression of Arrb2 2 0.48 0.45 1.66
157 INT98788 Negative_regulation of EPHB1 11 0.37 3.65 1.64
158 INT29763 Negative_regulation of Adora1 3 0.42 0 1.64
159 INT158773 Positive_regulation of Localization of Ephb1 1 0.34 0.08 1.64
160 INT241566 Negative_regulation of Negative_regulation of Calca 1 0.03 0.72 1.63
161 INT117717 Negative_regulation of Regulation of Ephb1 3 0.41 0.61 1.61
162 INT77314 Gene_expression of Lxn 3 0.76 5.67 1.55
163 INT147713 Localization of Ephb1 1 0.70 0 1.54
164 INT135907 Negative_regulation of Positive_regulation of Ephb1 1 0.38 0.42 1.51
165 INT48300 Regulation of Binding of Calca 2 0.39 0.73 1.49
166 INT135908 Regulation of Negative_regulation of Ephb1 1 0.24 0.4 1.49
167 INT135906 Positive_regulation of Positive_regulation of Ephb1 1 0.44 0.38 1.45
168 INT165085 Positive_regulation of Positive_regulation of Accn3 1 0.48 2.65 1.43
169 INT52250 Positive_regulation of Regulation of CALCA 1 0.48 0.08 1.43
170 INT212466 Regulation of EPHB1 7 0.37 5.72 1.42
171 INT129017 Negative_regulation of Phosphorylation of Ntrk1 3 0.41 1.5 1.42
172 INT241721 Positive_regulation of Transcription of Adora1 3 0.50 1.39 1.41
173 INT108936 Positive_regulation of Positive_regulation of Arrb2 1 0.41 0.25 1.4
174 INT78097 Negative_regulation of Regulation of CALCA 2 0.42 2.02 1.37
175 INT245532 Negative_regulation of Positive_regulation of Ntrk1 2 0.34 1.56 1.34
176 INT241737 Transcription of Adora1 3 0.72 0.89 1.32
177 INT36588 Protein_catabolism of Calca 7 0.87 1.98 1.31
178 INT158848 Negative_regulation of Gene_expression of Accn3 3 0.37 0.6 1.31
179 INT93612 Transcription of Ntrk1 2 0.52 1.31 1.26
180 INT117719 Transcription of Ephb1 2 0.44 0.06 1.25
181 INT166274 Gene_expression of EPHB1 14 0.55 8.2 1.19
182 INT141743 Positive_regulation of Positive_regulation of Accn3 2 0.39 1.11 1.19
183 INT302068 Phosphorylation of Arrb2 1 0.01 0.27 1.19
184 INT142309 Regulation of Gene_expression of Accn3 2 0.50 1.34 1.16
185 INT93610 Negative_regulation of Gene_expression of Ntrk1 2 0.41 0.84 1.15
186 INT76254 Positive_regulation of Positive_regulation of ADORA1 2 0.43 1.27 1.14
187 INT124069 Localization of Ntrk1 9 0.59 3.32 1.13
188 INT276839 Regulation of Transcription of Accn3 1 0.29 1.22 1.06
189 INT95719 Negative_regulation of Phosphorylation of Calca 1 0.41 0.09 1.02
190 INT95718 Positive_regulation of Phosphorylation of Calca 1 0.49 0.09 1.01
191 INT108943 Positive_regulation of Negative_regulation of Arrb2 1 0.61 0.06 0.97
192 INT240461 Regulation of Negative_regulation of Ephb1 4 0.37 1.66 0.96
193 INT129850 Binding of Lxn 1 0.37 0 0.89
194 INT215606 Positive_regulation of Localization of Adora1 3 0.49 0.44 0.87
195 INT54985 Positive_regulation of Regulation of Calca 2 0.47 0.33 0.86
196 INT201635 Positive_regulation of Positive_regulation of Ntrk1 3 0.40 1.15 0.85
197 INT92880 Localization of ADORA1 2 0.80 0.09 0.84
198 INT147716 Negative_regulation of Localization of Ephb1 1 0.51 0 0.84
199 INT97673 Protein_catabolism of Calca 1 0.50 0.15 0.82
200 INT97782 Protein_catabolism of Ephb1 5 0.86 1.27 0.76
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