GO:0050982

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Name detection of mechanical stimulus
Categary Process
Go Slim No
Go Link GO:0050982
Unique Molecular Interactions 81
Total Molecular Interactions 115
Total Single Events 408
Pain Genes Associated 8

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for detection of mechanical stimulus. They are ordered first by their pain relevance and then by number of times they were reported for detection of mechanical stimulus. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT148327 Binding of Pkd1 and Trpv1 1 0.52 2.23 1.01
2 INT241247 Binding of Pkd2 and Trpv4 1 0.54 1.22 0.52
3 INT126942 Binding of PKD2 and ZACN 1 0.00 1.38 0.28
4 INT234992 Car2 Positive_regulation of Jup 1 0.02 0.27 0.2
5 INT126944 Binding of PKD2 and Pkd1 2 0.08 2.09 0.19
6 INT241250 Binding of Pkd2 and Trpc1 1 0.23 0.3 0.17
7 INT126943 Binding of Pkd1 and ZACN 1 0.00 0.69 0.14
8 INT201762 JUP Regulation of Gene_expression of Ccnd1 1 0.03 0.8 0.13
9 INT201791 JUP Regulation of Gene_expression of Myc 1 0.49 0.8 0.13
10 INT148329 Pkd1 Positive_regulation of Trpv1 1 0.55 0.39 0.13
11 INT241248 Binding of Pkd1 and Pkd2 3 0.22 1.52 0.1
12 INT352751 Pkd2 Regulation of Localization of Vegfa 1 0.11 0.47 0.1
13 INT241252 Binding of Pkd1 and Tbpl1 1 0.02 0.79 0.1
14 INT352750 Pkd2 Positive_regulation of Vegfa 1 0.20 0.47 0.1
15 INT286568 Car2 Positive_regulation of Positive_regulation of Pkd1 1 0.03 0.16 0.09
16 INT241249 Pkd2 Regulation of Trpc1 1 0.21 0.14 0.09
17 INT286565 Pkd2 Positive_regulation of Positive_regulation of Pkd1 1 0.21 0.11 0.09
18 INT131130 Binding of PKD1 and Krt16 1 0.01 1 0.08
19 INT339111 Binding of ERBB2 and JUP 1 0.38 0.62 0.07
20 INT241246 Pkd2 Negative_regulation of Gene_expression of Trpv4 1 0.48 0.47 0.07
21 INT339108 Binding of ESR1 and JUP 1 0.38 0.62 0.07
22 INT349914 Binding of Cdh1 and Jup 1 0.11 0.47 0.07
23 INT286592 Binding of PKD1 and P1Ehs1 1 0.00 0.16 0.06
24 INT286591 Binding of PKD1 and Id2 1 0.07 0.17 0.06
25 INT234968 IgG Negative_regulation of Jup 1 0.02 1.09 0.06
26 INT241253 Gene_expression of Trpv4 Positive_regulation of Gene_expression of Pkd2 1 0.52 0.29 0.03
27 INT241251 Pkd2 Negative_regulation of Gene_expression of Gopc 1 0.12 0.24 0.03
28 INT192044 Binding of DSP and Jup 2 0.24 2.39 0
29 INT234995 Binding of CDH16 and Jup 1 0.00 0.27 0
30 INT245158 AD5 Regulation of PKD1 1 0.00 0.44 0
31 INT286562 Gene_expression of Pkd1 Positive_regulation of Ctnnb1 1 0.02 0.52 0
32 INT234969 Jup Regulation of Gene_expression of Dsp 1 0.01 0.54 0
33 INT235007 Binding of DSG1 and Jup 1 0.08 0.36 0
34 INT235005 Positive_regulation of Binding of DSG1 and Jup 1 0.08 0.36 0
35 INT286571 Binding of Prkd1 and Pkd1 1 0.05 0.76 0
36 INT303342 Binding of NPAT and TCAP 1 0.40 0 0
37 INT261883 PKD2 Positive_regulation of Localization of Ca2 1 0.02 0.67 0
38 INT272015 Pkd1 Positive_regulation of Localization of TSC1 1 0.18 0.65 0
39 INT234983 IgG Positive_regulation of Protein_catabolism of Jup 1 0.03 0.61 0
40 INT303404 Binding of TCAP and Jag1 1 0.39 0 0
41 INT192045 Jup Positive_regulation of RYR2 1 0.11 0.29 0
42 INT234970 Binding of Jup and Lat 1 0.01 0 0
43 INT266555 Mapk8 Regulation of JUP 1 0.08 0.1 0
44 INT286574 Gene_expression of Pkd1 Negative_regulation of Cdk2 1 0.10 0.09 0
45 INT286570 Pkd2 Positive_regulation of Binding of Pkd1 1 0.21 0.73 0
46 INT214919 Pkd1 Positive_regulation of CDKN1A 1 0.51 2.6 0
47 INT286501 Binding of PKD1 and LILRB1 1 0.01 1.07 0
48 INT234987 Binding of Jup and Dsp 1 0.01 0.18 0
49 INT286593 Binding of Pkd1 and GOPC 1 0.02 1.13 0
50 INT286589 Binding of PKHD1 and Pkd2 1 0.09 0.52 0
51 INT214917 Pkd1 Positive_regulation of Negative_regulation of CDKN1A 1 0.37 1.46 0
52 INT286573 Pkd2 Regulation of Pkd1 1 0.12 0.25 0
53 INT286564 Pkd1 Regulation of Mtor 1 0.00 0.51 0
54 INT286569 Binding of Pkd1 and Tsc2 1 0.06 1.01 0
55 INT286590 Binding of ID2 and Pkd2 1 0.13 0.13 0
56 INT192042 Binding of Jup and Ryr2 1 0.17 1.09 0
57 INT234982 Binding of Jup and Pkp1 1 0.00 0 0
58 INT286572 Binding of Ctnnb1 and Pkd1 1 0.02 0.96 0
59 INT286594 Binding of LILRB1 and Pkd1 1 0.01 1.07 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for detection of mechanical stimulus. They are ordered first by their pain relevance and then by number of times they were reported in detection of mechanical stimulus. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT148326 Gene_expression of Pkd1 7 0.76 5.38 1.85
2 INT148321 Positive_regulation of Gene_expression of Pkd1 5 0.68 2.93 1.21
3 INT152404 Regulation of PKD1 2 0.45 2.02 1.04
4 INT242171 Protein_catabolism of JUP 4 0.96 0.91 1.01
5 INT129174 Gene_expression of PKD1 24 0.67 14.91 0.74
6 INT137850 Gene_expression of PKD2 9 0.65 6.68 0.63
7 INT39728 Regulation of TCAP 1 0.00 0 0.61
8 INT241235 Binding of Pkd2 11 0.48 2.43 0.55
9 INT241243 Gene_expression of Pkd2 30 0.77 9.05 0.53
10 INT266535 Phosphorylation of JUP 3 0.79 0.63 0.49
11 INT242168 Transcription of JUP 4 0.67 1.17 0.46
12 INT148322 Localization of Pkd1 1 0.79 1.07 0.41
13 INT241236 Negative_regulation of Pkd2 11 0.43 1.82 0.39
14 INT150826 Positive_regulation of Pkd1 9 0.37 3.65 0.35
15 INT242169 Positive_regulation of Protein_catabolism of JUP 1 0.49 0.23 0.34
16 INT185886 Gene_expression of JUP 20 0.75 15.41 0.32
17 INT241240 Gene_expression of Pkd1 18 0.54 12.2 0.27
18 INT221860 Negative_regulation of Jup 9 0.15 6.82 0.26
19 INT241238 Positive_regulation of Pkd2 5 0.46 1.44 0.24
20 INT241244 Localization of Pkd2 1 0.74 0.35 0.24
21 INT234903 Gene_expression of Jup 1 0.23 7.1 0.2
22 INT208476 Binding of Pkd1 13 0.39 7.23 0.17
23 INT199521 Protein_catabolism of PKD1 2 0.96 0.39 0.15
24 INT148323 Binding of Pkd1 1 0.37 0.5 0.15
25 INT354535 Regulation of Negative_regulation of Pkd2 1 0.15 1.03 0.14
26 INT148324 Phosphorylation of Pkd1 1 0.81 0.52 0.14
27 INT205083 Positive_regulation of JUP 6 0.49 5.51 0.13
28 INT307335 Positive_regulation of Binding of Pkd1 1 0.35 0.23 0.12
29 INT242173 Positive_regulation of Gene_expression of JUP 2 0.49 2.37 0.09
30 INT309877 Localization of JUP 2 0.73 1.38 0.08
31 INT339206 Negative_regulation of Localization of JUP 1 0.41 1.1 0.08
32 INT234894 Negative_regulation of Protein_catabolism of Jup 1 0.17 2.87 0.08
33 INT234866 Regulation of Jup 2 0.08 0.58 0.06
34 INT234899 Positive_regulation of Protein_catabolism of Jup 1 0.21 0.88 0.06
35 INT329585 Regulation of Negative_regulation of Jup 1 0.01 0.23 0.06
36 INT286583 Localization of PKD2 1 0.35 0.17 0.06
37 INT234931 Protein_catabolism of Jup 1 0.29 2.23 0.06
38 INT234915 Positive_regulation of Gene_expression of Jup 1 0.15 2.7 0.06
39 INT354537 Positive_regulation of Positive_regulation of Pkd1 1 0.29 1.7 0.06
40 INT211006 Binding of PKD1 6 0.22 2.69 0.05
41 INT261879 Binding of PKD2 3 0.13 2.59 0.05
42 INT286543 Localization of Pkd1 5 0.52 3.74 0.04
43 INT241241 Positive_regulation of Gene_expression of Pkd2 3 0.50 1.3 0.03
44 INT234890 Phosphorylation of Jup 1 0.24 1.56 0.03
45 INT234867 Localization of Jup 1 0.24 2.84 0.03
46 INT271915 Negative_regulation of Pkd1 8 0.36 6.44 0
47 INT150827 Regulation of Pkd1 4 0.32 2.18 0
48 INT241239 Regulation of Pkd2 2 0.27 0.55 0
49 INT266537 Positive_regulation of Phosphorylation of JUP 2 0.49 0.29 0
50 INT175892 Negative_regulation of PKD1 2 0.42 1.03 0
51 INT241245 Negative_regulation of PKD2 2 0.42 2.35 0
52 INT266534 Negative_regulation of Phosphorylation of JUP 2 0.41 0.15 0
53 INT242174 Negative_regulation of Gene_expression of JUP 2 0.41 2.58 0
54 INT221864 Binding of JUP 2 0.36 1.05 0
55 INT221859 Binding of Jup 2 0.14 2.21 0
56 INT286546 Negative_regulation of Gene_expression of Pkd2 2 0.27 0.57 0
57 INT352724 Regulation of Gene_expression of Pkd2 1 0.10 0 0
58 INT309874 Positive_regulation of Binding of JUP 1 0.49 0.32 0
59 INT352716 Negative_regulation of Regulation of Pkd2 1 0.15 0.08 0
60 INT234877 Positive_regulation of Binding of Jup 1 0.21 0.24 0
61 INT242170 Negative_regulation of JUP 1 0.42 0.85 0
62 INT286545 Positive_regulation of Gene_expression of Pkd1 1 0.42 1.55 0
63 INT232493 Negative_regulation of Positive_regulation of PKD2 1 0.23 0.61 0
64 INT175898 Positive_regulation of PKD1 1 0.50 1.24 0
65 INT261880 Negative_regulation of Binding of PKD1 1 0.16 0.6 0
66 INT261878 Negative_regulation of Binding of PKD2 1 0.14 0.6 0
67 INT232491 Positive_regulation of PKD2 1 0.27 0.56 0
68 INT303380 Protein_catabolism of TCAP 1 0.64 0 0
69 INT286554 Negative_regulation of Gene_expression of Pkd1 1 0.35 1.77 0
70 INT175896 Transcription of PKD1 1 0.53 1.22 0
71 INT175890 Negative_regulation of Gene_expression of PKD1 1 0.42 0.11 0
72 INT309876 Regulation of JUP 1 0.60 0.67 0
73 INT234918 Positive_regulation of Jup 1 0.15 1.08 0
74 INT309875 Regulation of Gene_expression of JUP 1 0.44 0.39 0
75 INT214908 Positive_regulation of Gene_expression of PKD1 1 0.35 0.86 0
76 INT234896 Negative_regulation of Gene_expression of Jup 1 0.13 0.54 0
77 INT355092 Positive_regulation of Transcription of JUP 1 0.49 0.05 0
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