GO:0051020

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Name GTPase binding
Categary Function
Go Slim No
Go Link GO:0051020
Unique Molecular Interactions 40
Total Molecular Interactions 41
Total Single Events 225
Pain Genes Associated 15

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for GTPase binding. They are ordered first by their pain relevance and then by number of times they were reported for GTPase binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT151630 Il1rn Negative_regulation of Dock9 1 0.03 1.33 0.88
2 INT113611 Binding of Pick1 and Grip2 1 0.31 0.6 0.63
3 INT164973 Binding of RASA1 and Rgs7 1 0.00 0 0.54
4 INT164972 Binding of RASA1 and Rgs8 1 0.00 0 0.53
5 INT106114 Binding of ASIC2 and Pick1 1 0.14 0.1 0.4
6 INT106116 Binding of ASIC1 and Pick1 1 0.04 0.1 0.4
7 INT106115 Pick1 Positive_regulation of Phosphorylation of ASIC2 1 0.13 0.07 0.39
8 INT106117 Pick1 Positive_regulation of ASIC2 1 0.14 0.09 0.39
9 INT148397 Adra2c Regulation of Gnb3 1 0.12 0.08 0.19
10 INT234801 RAB3GAP1 Regulation of RAB3A 1 0.08 1.64 0.15
11 INT293697 Dock2 Positive_regulation of Akt1 1 0.14 0.08 0.13
12 INT304824 Binding of Rasa1 and Tnnc1 1 0.01 0 0.13
13 INT137632 Rasa1 Regulation of Ednrb 1 0.05 0 0.08
14 INT285025 Bnip3 Positive_regulation of Bak1 1 0.11 0.78 0.07
15 INT285032 Bnip3 Positive_regulation of Bax 1 0.28 0.77 0.07
16 INT297121 Binding of GNB3 and Eps8l3 1 0.00 0.81 0.05
17 INT247819 Cxadr Regulation of Gene_expression of Rasa1 1 0.06 1.04 0.04
18 INT191613 Binding of Nf1 and Rasa1 1 0.06 0.88 0.03
19 INT270938 Binding of Pick1 and Wnt2 1 0.00 0.18 0.03
20 INT225892 Binding of GAB1 and RASA1 1 0.01 0.06 0
21 INT331235 RASA1 Positive_regulation of Mtor 1 0.00 0.32 0
22 INT215243 Binding of Rab3a and Noc2l 1 0.00 0.26 0
23 INT271966 Phosphorylation of Rasa1 Positive_regulation of Tsc2 1 0.01 0.31 0
24 INT286422 Binding of Cdc42ep5 and Dock4 1 0.01 0.84 0
25 INT215241 Binding of Rab3a and Rph3a 1 0.00 0.26 0
26 INT225891 DOCK1 Positive_regulation of RAC1 1 0.01 0 0
27 INT293795 Binding of RASA1 and ras 1 0.00 0.08 0
28 INT225893 Binding of CRKL and DOCK1 1 0.01 0 0
29 INT331229 Rasa1 Positive_regulation of Mtor 1 0.00 0.32 0
30 INT331233 Binding of Mtor and Rasa1 1 0.00 0.32 0
31 INT215238 Binding of Rab3a and Sytl4 1 0.01 0.26 0
32 INT331236 Binding of RASA1 and Mtor 1 0.00 0.32 0
33 INT313074 Binding of Bnip3 and Map1lc3a 1 0.01 0.26 0
34 INT225899 Binding of DOCK1 and RAC1 1 0.01 0 0
35 INT225907 Binding of CRK and DOCK1 1 0.01 0 0
36 INT237354 Binding of DNM2 and Bin1 1 0.40 1.22 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for GTPase binding. They are ordered first by their pain relevance and then by number of times they were reported in GTPase binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT109833 Binding of GNB3 7 0.48 8.83 2.84
2 INT17993 Negative_regulation of RASA1 8 0.41 7.34 2.62
3 INT43900 Gene_expression of RASA1 13 0.58 12 2.03
4 INT230668 Gene_expression of Rasa1 9 0.68 3.25 1.74
5 INT106534 Gene_expression of Dock9 3 0.65 1.62 1.63
6 INT14916 Binding of RASA1 15 0.37 13.64 1.44
7 INT142623 Regulation of Gnb3 2 0.42 0.56 1.4
8 INT113607 Positive_regulation of Pick1 1 0.48 0.82 1.13
9 INT211723 Binding of Rasa1 3 0.07 0.85 1.03
10 INT116659 Regulation of Pick1 3 0.41 0.86 1.01
11 INT304823 Negative_regulation of Rasa1 6 0.10 0.39 0.76
12 INT84910 Gene_expression of GNB3 4 0.67 2.74 0.71
13 INT106106 Gene_expression of Pick1 3 0.70 0.66 0.68
14 INT106533 Positive_regulation of Gene_expression of Dock9 1 0.49 0.33 0.65
15 INT90416 Positive_regulation of RASA1 3 0.67 1.58 0.56
16 INT7248 Localization of RASA1 4 0.61 2.52 0.47
17 INT55893 Gene_expression of Rasa1 5 0.52 1.04 0.44
18 INT247798 Negative_regulation of Rasa1 3 0.09 1.05 0.44
19 INT230653 Phosphorylation of Rasa1 3 0.55 0.6 0.42
20 INT127085 Regulation of Gene_expression of Dock9 1 0.17 0.95 0.41
21 INT106108 Phosphorylation of Pick1 1 0.54 0.07 0.39
22 INT129343 Positive_regulation of Rasa1 2 0.10 1.03 0.37
23 INT234828 Gene_expression of RAB3A 2 0.30 2.05 0.37
24 INT84908 Positive_regulation of GNB3 1 0.49 0.9 0.32
25 INT208776 Positive_regulation of Gene_expression of GNB3 1 0.49 1.02 0.31
26 INT285014 Gene_expression of Bnip3 4 0.61 10.38 0.29
27 INT148395 Gene_expression of Gnb3 2 0.63 0.5 0.28
28 INT55894 Positive_regulation of Gene_expression of Rasa1 1 0.47 0.19 0.28
29 INT273222 Phosphorylation of Bin1 1 0.06 0.62 0.23
30 INT270959 Binding of Pick1 2 0.35 0.2 0.16
31 INT223459 Gene_expression of Dock4 2 0.71 1.5 0.16
32 INT201013 Regulation of Gene_expression of RASA1 1 0.05 0.16 0.16
33 INT223465 Regulation of Dock4 1 0.08 0.13 0.16
34 INT223463 Regulation of Gene_expression of Dock4 1 0.31 0.13 0.16
35 INT285018 Positive_regulation of Bnip3 1 0.34 1.67 0.15
36 INT55892 Negative_regulation of Gene_expression of Rasa1 1 0.29 0.1 0.15
37 INT304822 Regulation of Negative_regulation of Rasa1 1 0.05 0 0.14
38 INT304820 Transcription of Rasa1 1 0.10 0 0.12
39 INT201009 Transcription of RASA1 1 0.07 0.14 0.12
40 INT320585 Negative_regulation of Gene_expression of Pick1 1 0.31 0.1 0.11
41 INT320586 Positive_regulation of Gene_expression of Pick1 1 0.50 0.1 0.11
42 INT349974 Positive_regulation of Rasa1 1 0.04 0.92 0.11
43 INT320584 Negative_regulation of Pick1 1 0.31 0.09 0.08
44 INT285002 Negative_regulation of Gene_expression of Bnip3 1 0.37 0.75 0.07
45 INT285010 Positive_regulation of Positive_regulation of Bnip3 1 0.32 0.77 0.07
46 INT285020 Binding of Bnip3 1 0.22 0.71 0.07
47 INT247808 Negative_regulation of Localization of Rasa1 1 0.06 0.96 0.04
48 INT247815 Localization of Rasa1 1 0.10 1.69 0.04
49 INT237347 Binding of Bin1 1 0.36 0.44 0.03
50 INT225851 Phosphorylation of RASA1 2 0.05 0.14 0
51 INT230655 Regulation of Gene_expression of Rasa1 1 0.54 0.26 0
52 INT225858 Binding of DOCK1 1 0.05 0 0
53 INT286398 Positive_regulation of Transcription of Dock4 1 0.46 0 0
54 INT215230 Gene_expression of Rab3a 1 0.02 0.39 0
55 INT247790 Regulation of Rasa1 1 0.05 1.44 0
56 INT215227 Positive_regulation of Gene_expression of Rab3a 1 0.02 0.39 0
57 INT230656 Positive_regulation of Gene_expression of Rasa1 1 0.61 0.24 0
58 INT291974 Regulation of RASA1 1 0.03 0.29 0
59 INT346853 Binding of Rasa1 1 0.09 1.24 0
60 INT337961 Gene_expression of Bnip3 1 0.51 0.89 0
61 INT215232 Binding of Rab3a 1 0.01 0.25 0
62 INT286408 Transcription of Dock4 1 0.66 0 0
63 INT335031 Positive_regulation of Gene_expression of RASA1 1 0.09 1.49 0
64 INT296001 Positive_regulation of Gene_expression of Bnip3 1 0.55 2.47 0
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