GO:0051023

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Name regulation of immunoglobulin secretion
Categary Process
Go Slim No
Go Link GO:0051023
Unique Molecular Interactions 1180
Total Molecular Interactions 1710
Total Single Events 17140
Pain Genes Associated 13

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for regulation of immunoglobulin secretion. They are ordered first by their pain relevance and then by number of times they were reported for regulation of immunoglobulin secretion. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT188692 Binding of Cd40 and Cd40lg 32 0.34 22.95 6.62
2 INT140935 Binding of Cd40lg and Cd40 1 0.30 6.34 5.61
3 INT139706 Tnf Positive_regulation of Ltp 1 0.03 2.61 4.63
4 INT101942 Binding of CD40 and CD40LG 16 0.23 15.24 4.01
5 INT61359 TNF Positive_regulation of NFKB1 11 0.63 6.66 3.89
6 INT146412 Tnf Positive_regulation of Gene_expression of Trpv1 2 0.66 5.22 3.22
7 INT140024 Tnf Positive_regulation of Gene_expression of Il1b 2 0.49 2.75 2.61
8 INT152501 Binding of Tnf and Tnfrsf1a 4 0.31 3 2.58
9 INT151826 Tnf Positive_regulation of TNF 1 0.04 3.38 2.51
10 INT117532 SETBP1 Positive_regulation of Gene_expression of TNF 1 0.54 0.85 2.44
11 INT122163 Binding of TNF and TNFRSF1B 6 0.44 6.06 2.41
12 INT61733 Tlr4 Positive_regulation of Gene_expression of Tnf 3 0.26 1.99 2.36
13 INT139705 Negative_regulation of Tnf Positive_regulation of Ltp 1 0.03 1.19 2.3
14 INT279361 Binding of TNF and KLF1 4 0.00 3.72 2.19
15 INT94491 Il1b Positive_regulation of Gene_expression of Tnf 1 0.25 3.81 2.19
16 INT94504 Il6 Positive_regulation of Gene_expression of Tnf 1 0.30 3.8 2.19
17 INT86179 TNF Positive_regulation of Localization of IL6 5 0.35 1.66 2.17
18 INT83425 Binding of CD40LG and IGHG3 11 0.21 4.56 2.09
19 INT148704 Binding of TNF and TNFRSF1A 5 0.44 3.3 2.09
20 INT196586 Negative_regulation of Mapk14 Negative_regulation of TNF 2 0.04 2.02 2.08
21 INT140032 Tnf Positive_regulation of Gene_expression of Ifng 2 0.43 2.23 2
22 INT140026 Il1b Positive_regulation of Gene_expression of Tnf 2 0.49 2.23 2
23 INT217042 IRF6 Positive_regulation of TNF 4 0.27 3.03 1.95
24 INT129212 RYBP Positive_regulation of Tnf 2 0.03 1.9 1.95
25 INT279359 Binding of ADA and TNF 1 0.20 2.61 1.91
26 INT199287 TNF Positive_regulation of Transcription of Oprm1 2 0.02 1.86 1.8
27 INT224432 TNF Positive_regulation of Gene_expression of VEGFA 1 0.13 5.83 1.8
28 INT137207 Tnf Positive_regulation of Nfkb1 3 0.23 2.69 1.71
29 INT167427 Mapk8 Regulation of Regulation of Tnf 1 0.26 2.83 1.7
30 INT89379 TNF Positive_regulation of Gene_expression of IL6 5 0.50 4.37 1.69
31 INT79778 Tlr4 Positive_regulation of Localization of TNF 4 0.08 4.21 1.61
32 INT167202 TNF Regulation of Gene_expression of Ngf 1 0.10 1.47 1.6
33 INT209853 TNF Regulation of Gene_expression of CD36 1 0.61 3.41 1.59
34 INT266767 SFTPA1 Positive_regulation of Gene_expression of TNF 1 0.01 1.69 1.59
35 INT198653 TNF Positive_regulation of MIF 1 0.15 3.81 1.55
36 INT252633 Binding of TNF and Tnfrsf1b 4 0.05 3.66 1.54
37 INT167201 Gtf3a Regulation of TNF 1 0.01 1.39 1.52
38 INT158775 Regulation of Tnf Regulation of Ephb1 1 0.18 0.09 1.52
39 INT158777 Tnf Regulation of Ephb1 1 0.18 0.09 1.51
40 INT140029 Ifng Positive_regulation of Gene_expression of Tnf 1 0.43 1.69 1.5
41 INT285569 TNF Negative_regulation of Gene_expression of Il6 1 0.03 2.83 1.46
42 INT72755 Tap1 Negative_regulation of TNF 1 0.43 2.45 1.46
43 INT236365 Binding of CD40LG and IL6 3 0.20 4.16 1.42
44 INT131156 Binding of RUNX1 and TNF 2 0.03 3.44 1.42
45 INT161513 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Tnf 1 0.33 0.27 1.35
46 INT160588 TNF Positive_regulation of Gene_expression of OPRM1 1 0.20 0.54 1.35
47 INT56087 TNF Regulation of Gene_expression of SERPINE1 1 0.43 1.67 1.33
48 INT186393 Binding of TNF and Tnfrsf1a 9 0.37 8.55 1.29
49 INT130333 FUT3 Negative_regulation of Positive_regulation of Tnf 1 0.01 0.36 1.29
50 INT70037 TNF Regulation of IL10 2 0.09 2.11 1.26
51 INT296796 Tbrs1 Positive_regulation of Gene_expression of TNF 1 0.00 1.58 1.26
52 INT197092 TNF Regulation of VEGFA 4 0.21 2.78 1.22
53 INT131807 Bpifa2 Positive_regulation of Localization of Tnf 1 0.32 2.09 1.22
54 INT70035 TNF Regulation of Negative_regulation of PRF1 1 0.05 1.42 1.21
55 INT70032 TNF Regulation of PRF1 1 0.05 1.42 1.21
56 INT70040 TNF Regulation of Negative_regulation of IL10 1 0.09 1.42 1.21
57 INT328743 TNF Positive_regulation of Mapk14 1 0.04 1.4 1.21
58 INT194619 Il15 Positive_regulation of Gene_expression of TNF 1 0.24 2.23 1.2
59 INT133046 TNF Positive_regulation of Positive_regulation of NFKB1 5 0.54 3.23 1.19
60 INT113242 TNF Regulation of Transcription of OPRM1 2 0.45 1.53 1.19
61 INT314196 Ngf Positive_regulation of Tnf 1 0.50 1.98 1.18
62 INT231769 TNF Negative_regulation of Gene_expression of HMOX1 1 0.26 4.75 1.15
63 INT72754 Adamts7 Negative_regulation of TNF 1 0.28 1.64 1.13
64 INT89938 Tlr4 Positive_regulation of Gene_expression of TNF 6 0.25 1.3 1.12
65 INT107264 Binding of TNF and NCR3 1 0.30 1.42 1.1
66 INT139704 Tnf Positive_regulation of Mapk14 1 0.22 0.73 1.1
67 INT107266 Binding of HLA-DRB1 and TNF 1 0.29 1.41 1.1
68 INT267597 IL10 Negative_regulation of Gene_expression of TNF 1 0.03 2.24 1.1
69 INT107267 Binding of HLA-A and TNF 1 0.34 1.41 1.1
70 INT94495 Tnf Positive_regulation of Gene_expression of Il6 1 0.30 1.9 1.09
71 INT151825 Tnf Positive_regulation of Mapk14 1 0.22 1.72 1.09
72 INT94500 Tnf Positive_regulation of Gene_expression of Il1b 1 0.25 1.9 1.09
73 INT139703 Tnf Positive_regulation of Mapk8 1 0.32 0.73 1.08
74 INT152502 Tnf Negative_regulation of Binding of Tnfrsf1a 1 0.37 0.6 1.08
75 INT119108 Binding of LTBR and TNF 2 0.15 1.47 1.07
76 INT114364 Hmgb1 Positive_regulation of Gene_expression of TNF 2 0.05 1.85 1.06
77 INT120312 Ghrh Regulation of Tnf 1 0.26 0.95 1.05
78 INT131853 CD40 Negative_regulation of Gene_expression of CD40LG 1 0.09 1.54 1.05
79 INT120314 Ghrh Regulation of Positive_regulation of Tnf 1 0.43 0.95 1.05
80 INT152504 Binding of CR1 and Tnf 1 0.00 0.49 1.04
81 INT133650 Epo Negative_regulation of TNF 1 0.35 2.7 1.04
82 INT156245 NFKB1 Positive_regulation of Regulation of TNF 1 0.45 0.76 1.03
83 INT81545 Tnf Positive_regulation of Gtf3a 2 0.03 1.41 1.02
84 INT308804 Pld1 Positive_regulation of TNF 1 0.05 2.42 0.99
85 INT274895 Positive_regulation of Cbr2 Negative_regulation of Gene_expression of TNF 1 0.06 1.21 0.99
86 INT129216 Negative_regulation of RYBP Positive_regulation of Tnf 1 0.01 1.24 0.98
87 INT140936 Binding of Cd40lg and Ean5 1 0.07 1.03 0.98
88 INT140934 Binding of Cd40 and Ean5 1 0.09 1.03 0.98
89 INT182022 TNF Positive_regulation of Gene_expression of Tnfrsf11b 1 0.06 1.56 0.98
90 INT209852 TNF Negative_regulation of Gene_expression of CD36 1 0.43 0.61 0.98
91 INT154255 Tnf Positive_regulation of IL1B 1 0.54 0.94 0.97
92 INT154254 Tnf Positive_regulation of Il6 1 0.36 0.94 0.97
93 INT114320 TNF Positive_regulation of Gene_expression of Il6 1 0.07 1.73 0.97
94 INT103133 TNF Positive_regulation of Gene_expression of IL8 2 0.48 1.26 0.96
95 INT133652 Epo Negative_regulation of Gene_expression of TNF 1 0.35 2.64 0.96
96 INT171264 TNF Positive_regulation of MMP1 2 0.10 2.05 0.95
97 INT188805 TNF Positive_regulation of Gene_expression of Crp 1 0.15 2.96 0.95
98 INT100018 TNF Positive_regulation of MAPK1 3 0.24 1.56 0.94
99 INT133050 TNF Positive_regulation of Gene_expression of ICAM1 3 0.67 1.91 0.94
100 INT182024 TNF Positive_regulation of Gene_expression of Il6 1 0.05 1.58 0.94
101 INT129211 RYBP Positive_regulation of Gene_expression of Tnf 1 0.01 1.04 0.94
102 INT155259 RUNX1 Negative_regulation of Tnf 1 0.00 1.48 0.93
103 INT165280 Tnf Positive_regulation of Gene_expression of Nos2 1 0.24 1.02 0.91
104 INT254242 TNF Positive_regulation of Gene_expression of DKK1 1 0.14 1.24 0.91
105 INT256646 Tnf Positive_regulation of Positive_regulation of Nfkb1 1 0.22 1.83 0.9
106 INT222988 TNF Positive_regulation of Protein_catabolism of COL1A1 1 0.01 1.66 0.9
107 INT211128 Binding of P4HB and TNF 1 0.09 0.97 0.9
108 INT211129 Negative_regulation of Binding of P4HB and TNF 1 0.10 0.97 0.9
109 INT120147 Tlr4 Positive_regulation of Tnf 3 0.39 2.14 0.89
110 INT80132 Binding of HLA-B and TNF 1 0.04 1.15 0.89
111 INT142278 Slc8a1 Regulation of Tnf 1 0.14 0.07 0.89
112 INT167466 Ccdc80 Negative_regulation of Tnf 1 0.01 0.76 0.88
113 INT134311 Tnf Positive_regulation of Protein_catabolism of Nfkbia 1 0.18 0.57 0.88
114 INT116556 Olr1627 Negative_regulation of Regulation of Tnf 1 0.01 1.52 0.87
115 INT97795 IRF6 Positive_regulation of Localization of TNF 3 0.09 1.57 0.86
116 INT160413 Tat Positive_regulation of Gene_expression of Cd40lg 1 0.50 0.98 0.86
117 INT152868 Tnf Regulation of Gene_expression of Trpv1 1 0.27 0.25 0.86
118 INT125234 Positive_regulation of Binding of BCR and CD40LG 1 0.31 0.76 0.86
119 INT110315 Negative_regulation of ALOX5 Negative_regulation of Gene_expression of TNF 1 0.47 0.74 0.85
120 INT125233 Binding of BCR and CD40LG 1 0.23 0.75 0.85
121 INT215598 Positive_regulation of P2rx7 Positive_regulation of Localization of TNF 1 0.22 1.44 0.85
122 INT196638 TNF Positive_regulation of F2RL1 2 0.09 1.52 0.84
123 INT146919 Tnf Positive_regulation of Gene_expression of Ccl2 1 0.16 1.44 0.84
124 INT238641 Binding of TNF and Ifx 1 0.07 0.86 0.84
125 INT238642 Binding of TNF and Ada 1 0.03 0.86 0.84
126 INT105435 TNF Positive_regulation of IL6 5 0.25 4.45 0.83
127 INT149626 Il1b Regulation of Gene_expression of Tnf 1 0.41 0.83 0.83
128 INT102201 Tnf Regulation of Il1b 3 0.39 2.57 0.82
129 INT162071 Gene_expression of MC1R Negative_regulation of Gene_expression of TNF 1 0.41 0.34 0.82
130 INT66206 Negative_regulation of TNF Positive_regulation of NFKB1 2 0.53 1.71 0.81
131 INT126555 Binding of Ighg1 and Tnf 1 0.35 2.2 0.8
132 INT147755 Binding of GNRH1 and TNF 1 0.32 2.37 0.79
133 INT110518 Tnf Positive_regulation of Prkce 1 0.26 1.43 0.78
134 INT188531 Binding of TNF and PDXK 1 0.03 1.99 0.78
135 INT102163 Binding of TNF and Mmp9 1 0.12 0.88 0.78
136 INT306259 HDAC9 Negative_regulation of Gene_expression of TNF 1 0.21 0.89 0.78
137 INT102161 Binding of TNF and Mmp2 1 0.10 0.88 0.78
138 INT306258 HDAC4 Negative_regulation of Gene_expression of TNF 1 0.09 0.89 0.78
139 INT130138 TNF Negative_regulation of Gene_expression of S100A10 1 0.06 1.32 0.78
140 INT102162 Binding of TNF and Adam17 1 0.14 0.88 0.78
141 INT296797 Tlr9 Regulation of Positive_regulation of TNF 1 0.03 1.37 0.77
142 INT296798 Gopc Regulation of Positive_regulation of TNF 1 0.01 1.37 0.77
143 INT152869 Tnf Positive_regulation of Gene_expression of Trpv1 1 0.46 0.48 0.77
144 INT209883 TNF Positive_regulation of Gene_expression of TNFRSF11A 1 0.20 1.83 0.77
145 INT194644 Tlr4 Positive_regulation of TNF 6 0.58 2.42 0.76
146 INT149192 TNF Positive_regulation of Gene_expression of VCAM1 3 0.57 1.4 0.76
147 INT26497 TNF Positive_regulation of Gene_expression of MMP2 1 0.44 1.5 0.75
148 INT113472 TNF Positive_regulation of Localization of MMP14 1 0.47 0.45 0.75
149 INT308176 TNF Regulation of Tnfrsf1a 1 0.05 1.19 0.75
150 INT354455 Il11 Negative_regulation of Gene_expression of Tnf 1 0.31 1.21 0.74
151 INT301141 Nsa2 Positive_regulation of TNF 1 0.01 0.6 0.74
152 INT301142 Negative_regulation of Nsa2 Positive_regulation of TNF 1 0.01 0.6 0.74
153 INT4875 TNF Regulation of MME 1 0.51 0.71 0.74
154 INT86657 TNF Regulation of H2-Ab1 1 0.02 0.84 0.74
155 INT190174 TNF Positive_regulation of MMP12 1 0.27 0.08 0.74
156 INT96301 Olr1742 Negative_regulation of Gene_expression of Tnf 1 0.14 0 0.74
157 INT211127 Regulation of Binding of MTX1 and TNF 1 0.22 0.71 0.74
158 INT211130 Binding of MTX1 and TNF 1 0.18 0.7 0.73
159 INT172147 Binding of IL15 and TNF 2 0.05 1.19 0.72
160 INT150992 Sfpq Negative_regulation of Gene_expression of Tnf 1 0.03 0.69 0.72
161 INT51006 PDYN Positive_regulation of TNF 1 0.11 0.84 0.72
162 INT236364 CD40LG Positive_regulation of Gene_expression of IL6 1 0.25 1.37 0.72
163 INT117535 SND1 Positive_regulation of Gene_expression of TNF 1 0.06 0.29 0.71
164 INT113499 TNF Positive_regulation of Gene_expression of BHLHE23 1 0.25 0.1 0.71
165 INT159963 Tnf Positive_regulation of Localization of Il6 1 0.12 2.32 0.71
166 INT187115 Binding of TIMP1 and TNF 2 0.30 1.07 0.7
167 INT171901 Binding of TNF and Il1 2 0.18 1.07 0.7
168 INT117534 TNF Positive_regulation of Positive_regulation of SND1 1 0.06 0.29 0.7
169 INT117533 TNF Positive_regulation of Positive_regulation of SETBP1 1 0.34 0.29 0.7
170 INT83628 TNF Positive_regulation of Gene_expression of Cd59 1 0.06 1.09 0.7
171 INT172143 IL4 Positive_regulation of Protein_catabolism of TNF 2 0.11 1.7 0.69
172 INT172146 IL10 Positive_regulation of Protein_catabolism of TNF 2 0.15 1.69 0.69
173 INT83625 Tnf Positive_regulation of Gene_expression of Cd59 1 0.15 1.08 0.69
174 INT334395 IL1B Positive_regulation of Tnf 1 0.11 2.83 0.69
175 INT113959 TNF Positive_regulation of Gene_expression of IK 1 0.02 0.66 0.69
176 INT190527 TNF Positive_regulation of Gene_expression of Ros1 1 0.01 1.02 0.68
177 INT119107 Negative_regulation of Binding of LTBR and TNF 1 0.17 1.16 0.68
178 INT203758 Binding of IL6 and TNF 3 0.26 2.03 0.67
179 INT231349 Il10 Negative_regulation of Gene_expression of TNF 2 0.23 1.82 0.67
180 INT119105 Binding of FCGR1A and TNF 1 0.03 1.16 0.67
181 INT119106 Negative_regulation of Binding of FCGR1A and TNF 1 0.03 1.16 0.67
182 INT264338 Binding of IL-17 and Positive_regulation of Localization of TNF 1 0.04 1.71 0.67
183 INT314199 Mapk14 Regulation of Tnf 1 0.26 0.71 0.67
184 INT148139 Phosphorylation of Mapk14 Positive_regulation of Positive_regulation of Tnf 1 0.46 0.98 0.66
185 INT137142 Binding of ITIH4 and Positive_regulation of Localization of TNF 1 0.40 0.71 0.66
186 INT148138 Mapk14 Positive_regulation of Positive_regulation of Tnf 1 0.64 0.98 0.66
187 INT252293 Binding of TNF and Positive_regulation of Gene_expression of Ccl20 1 0.04 0.54 0.66
188 INT120144 Negative_regulation of Tlr4 Positive_regulation of Tnf 1 0.18 0.91 0.66
189 INT120146 seb Positive_regulation of Gene_expression of Tnf 1 0.40 0.86 0.66
190 INT120145 seb Positive_regulation of Tnf 1 0.40 0.85 0.65
191 INT254230 Ik Negative_regulation of Gene_expression of TNF 1 0.00 1.29 0.65
192 INT132689 Tnf Regulation of Dnajc13 1 0.01 1.27 0.65
193 INT295705 Binding of IK and TNF 1 0.00 0.27 0.64
194 INT292893 TNF Regulation of IL8 2 0.27 1.3 0.63
195 INT165047 Mapk14 Positive_regulation of Gene_expression of Tnf 1 0.73 0.8 0.63
196 INT176476 TNF Positive_regulation of Gene_expression of SELE 1 0.04 0.57 0.63
197 INT220117 Il6 Positive_regulation of TNF 1 0.01 2.45 0.63
198 INT165048 Trib3 Positive_regulation of Gene_expression of Tnf 1 0.08 0.8 0.63
199 INT148137 Tnf Positive_regulation of Positive_regulation of Mapk14 1 0.46 1 0.63
200 INT100030 TNF Positive_regulation of Mapk8 1 0.12 1.57 0.63

Single Events

The table below shows the top 100 pain related interactions that have been reported for regulation of immunoglobulin secretion. They are ordered first by their pain relevance and then by number of times they were reported in regulation of immunoglobulin secretion. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82
2 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98
3 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81
4 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68
5 INT6852 Localization of TNF 883 0.81 705.95 270.84
6 INT6481 Binding of TNF 624 0.48 510.2 214.82
7 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210
8 INT6488 Gene_expression of Tnf 484 0.78 339.61 191.58
9 INT13353 Positive_regulation of Tnf 332 0.70 248.75 148.1
10 INT9660 Regulation of TNF 363 0.62 312.94 139.99
11 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61
12 INT10166 Localization of Tnf 237 0.81 153.95 88.64
13 INT9236 Regulation of Gene_expression of TNF 204 0.62 162.66 72.99
14 INT58400 Negative_regulation of Tnf 182 0.59 129.97 71
15 INT49995 Positive_regulation of Gene_expression of Tnf 187 0.70 125.07 70.54
16 INT6489 Positive_regulation of Gene_expression of Tnf 140 0.70 92.31 67.85
17 INT6486 Positive_regulation of Tnf 168 0.70 123.47 66.05
18 INT52800 Negative_regulation of Gene_expression of Tnf 142 0.59 92.27 55.47
19 INT22112 Positive_regulation of Localization of TNF 164 0.70 115.66 52.18
20 INT66029 Negative_regulation of Tnf 100 0.59 84.28 48.16
21 INT55670 Negative_regulation of Gene_expression of Tnf 83 0.59 57.16 46.33
22 INT4216 Gene_expression of CD40LG 328 0.78 256.02 44.23
23 INT5307 Regulation of Tnf 87 0.62 78.71 43.4
24 INT13354 Transcription of TNF 108 0.72 85.81 42.32
25 INT53577 Negative_regulation of Localization of TNF 110 0.59 59.28 35.23
26 INT35406 Localization of Tnf 94 0.81 64.63 31.65
27 INT52801 Regulation of Gene_expression of Tnf 55 0.62 48.74 26.59
28 INT66753 Negative_regulation of Positive_regulation of Tnf 45 0.59 35.28 22.33
29 INT8483 Positive_regulation of Positive_regulation of TNF 73 0.67 60.35 22.03
30 INT96156 Gene_expression of Cd40 144 0.77 56.95 21.7
31 INT53575 Regulation of Gene_expression of Tnf 46 0.62 34.35 20.63
32 INT53574 Regulation of Tnf 45 0.62 40.68 19.71
33 INT66751 Negative_regulation of Localization of Tnf 48 0.59 26 19.36
34 INT66755 Transcription of Tnf 45 0.72 37.1 19.11
35 INT18010 Positive_regulation of CD40LG 122 0.70 100.8 18.46
36 INT80755 Gene_expression of CD40 88 0.75 53.68 17.86
37 INT10169 Positive_regulation of Localization of Tnf 44 0.70 27.71 16.75
38 INT19929 Negative_regulation of Positive_regulation of TNF 52 0.59 38.16 16.51
39 INT49986 Transcription of Tnf 25 0.72 18.3 16.22
40 INT12087 Regulation of Localization of TNF 44 0.62 28.71 15.17
41 INT10173 Binding of Tnf 45 0.48 35.6 14.32
42 INT133156 Binding of Cd40 77 0.48 45.92 13.77
43 INT64048 Positive_regulation of Positive_regulation of Tnf 32 0.70 21.24 13.74
44 INT6478 Negative_regulation of Binding of TNF 36 0.58 30.42 13.31
45 INT89404 Regulation of Negative_regulation of TNF 30 0.45 24.47 12.71
46 INT24816 Binding of CD40LG 68 0.47 45.48 11.56
47 INT51265 Phosphorylation of TNF 32 0.81 25.33 10.75
48 INT60434 Negative_regulation of Positive_regulation of Tnf 20 0.46 10.01 10.64
49 INT80110 Regulation of Positive_regulation of TNF 34 0.44 25.79 9.78
50 INT85966 Gene_expression of Cd40lg 50 0.73 30.9 9.11
51 INT48860 Regulation of Localization of Tnf 25 0.61 20.68 8.78
52 INT53573 Negative_regulation of Localization of Tnf 19 0.59 11.57 8.54
53 INT86411 Negative_regulation of Negative_regulation of TNF 24 0.42 17.6 7.89
54 INT49490 Positive_regulation of Transcription of TNF 19 0.70 14.76 7.58
55 INT68299 Binding of Tnf 17 0.39 12.55 7.49
56 INT66752 Positive_regulation of Transcription of Tnf 15 0.68 10.86 7.26
57 INT93003 Binding of CD40 28 0.47 20.25 7.13
58 INT1124 Negative_regulation of CD40LG 53 0.57 36.26 7
59 INT69985 Positive_regulation of Negative_regulation of TNF 21 0.50 13.26 6.31
60 INT83451 Positive_regulation of Gene_expression of CD40LG 26 0.60 22.81 6.25
61 INT172084 Positive_regulation of Binding of TNF 21 0.50 15.31 6.06
62 INT67060 Negative_regulation of Transcription of TNF 17 0.59 12.94 5.88
63 INT6487 Positive_regulation of Positive_regulation of Tnf 21 0.56 16.06 5.64
64 INT142607 Positive_regulation of Gene_expression of Cd40 41 0.62 13.85 5.51
65 INT58145 Positive_regulation of Localization of Tnf 20 0.67 13.33 5.44
66 INT45753 Localization of CD40LG 45 0.79 32.31 5.28
67 INT92054 Positive_regulation of Transcription of Tnf 8 0.50 4.93 5.05
68 INT55698 Regulation of Binding of TNF 13 0.44 8.98 4.74
69 INT101594 Positive_regulation of Cd40 36 0.69 16.14 4.56
70 INT85965 Binding of Cd40lg 26 0.45 16.76 4.52
71 INT5148 Regulation of CD40LG 25 0.44 21.58 4.05
72 INT66754 Negative_regulation of Transcription of Tnf 11 0.43 8.43 3.93
73 INT23088 Phosphorylation of Tnf 15 0.79 9.85 3.82
74 INT172173 Protein_catabolism of TNF 16 0.96 9.95 3.79
75 INT140932 Binding of Cd40 1 0.44 4.19 3.6
76 INT140933 Binding of Cd40lg 1 0.38 4.2 3.6
77 INT93915 Positive_regulation of Gene_expression of CD40 14 0.44 12.45 3.35
78 INT140931 Gene_expression of Cd40lg 5 0.61 5.2 3.33
79 INT85971 Positive_regulation of Gene_expression of Cd40lg 14 0.66 7.61 3.29
80 INT125237 Negative_regulation of Gene_expression of CD40LG 16 0.54 9.9 3.27
81 INT142606 Regulation of Gene_expression of Cd40 13 0.56 6.15 3.27
82 INT65427 Regulation of Positive_regulation of Tnf 7 0.60 3.49 3.22
83 INT85970 Positive_regulation of Cd40lg 21 0.53 8.51 3.16
84 INT93913 Positive_regulation of CD40 21 0.58 23.47 3.1
85 INT140929 Gene_expression of Cd40 9 0.72 8.76 2.88
86 INT95049 Negative_regulation of Regulation of Tnf 4 0.42 1.64 2.84
87 INT75736 Regulation of Localization of Tnf 6 0.62 4.61 2.67
88 INT96151 Negative_regulation of Gene_expression of Cd40 20 0.58 6.06 2.58
89 INT98607 Regulation of Regulation of TNF 8 0.44 6.95 2.56
90 INT248297 Negative_regulation of Cd40 14 0.58 8.96 2.34
91 INT66804 Negative_regulation of Negative_regulation of Tnf 4 0.56 2.79 2.26
92 INT114898 Regulation of Transcription of TNF 4 0.35 2.69 2.18
93 INT122649 Positive_regulation of Regulation of Tnf 2 0.49 2.78 1.96
94 INT77801 Negative_regulation of Binding of Tnf 5 0.42 3.93 1.77
95 INT159957 Positive_regulation of Phosphorylation of Tnf 3 0.49 2.63 1.65
96 INT51840 Positive_regulation of Localization of CD40LG 8 0.69 9.59 1.58
97 INT183791 Positive_regulation of Phosphorylation of TNF 6 0.49 4.72 1.56
98 INT61967 Positive_regulation of Negative_regulation of Tnf 3 0.50 2.46 1.49
99 INT93001 Localization of CD40 4 0.78 1.97 1.45
100 INT83659 Negative_regulation of Binding of Tnf 3 0.37 1.57 1.42
101 INT188691 Negative_regulation of Binding of Cd40 3 0.42 2.49 1.31
102 INT190067 Binding of Traf2 5 0.20 3.28 1.27
103 INT298979 Gene_expression of Traf6 5 0.31 1.75 1.21
104 INT189836 Regulation of Cd40 10 0.40 3.02 1.1
105 INT129587 Protein_catabolism of Tnf 2 0.86 1.41 1.08
106 INT168276 Negative_regulation of Phosphorylation of Tnf 1 0.19 1.3 1.08
107 INT188667 Localization of Cd40lg 5 0.57 3.29 1.07
108 INT135027 Regulation of Positive_regulation of Tnf 3 0.38 2.84 1.05
109 INT188664 Negative_regulation of Cd40lg 7 0.33 3.99 1.04
110 INT140928 Negative_regulation of Gene_expression of Cd40lg 1 0.46 1.09 1.01
111 INT140930 Positive_regulation of Gene_expression of Cd40 4 0.64 3.26 0.99
112 INT134307 Negative_regulation of Protein_catabolism of Tnf 1 0.41 0.57 0.88
113 INT115822 Regulation of Transcription of Tnf 3 0.35 1.96 0.87
114 INT134310 Positive_regulation of Protein_catabolism of Tnf 1 0.49 0.57 0.87
115 INT160406 Transcription of Cd40lg 2 0.52 1.52 0.83
116 INT170603 Negative_regulation of Gene_expression of CD40 5 0.32 2.18 0.78
117 INT136690 Regulation of Negative_regulation of Tnf 5 0.45 3.58 0.78
118 INT102199 Regulation of Transcription of Tnf 2 0.45 2.25 0.78
119 INT237158 Negative_regulation of Negative_regulation of Tnf 2 0.13 1.37 0.74
120 INT250281 Positive_regulation of Positive_regulation of CD40LG 3 0.23 3.19 0.73
121 INT5211 Localization of Cd40 6 0.78 1.75 0.71
122 INT85969 Regulation of Gene_expression of Cd40lg 2 0.43 1.96 0.69
123 INT285262 Regulation of Cd40lg 3 0.34 1.48 0.66
124 INT178201 Negative_regulation of Binding of Cd40lg 2 0.33 2.92 0.64
125 INT97130 Negative_regulation of CD40 5 0.35 1.96 0.63
126 INT51263 Regulation of Phosphorylation of TNF 2 0.26 1.06 0.63
127 INT188799 Positive_regulation of Protein_catabolism of Traf6 2 0.19 1.98 0.62
128 INT235079 Negative_regulation of Phosphorylation of TNF 2 0.41 1.16 0.6
129 INT130373 Regulation of Gene_expression of CD40LG 3 0.60 1.87 0.59
130 INT154745 Protein_catabolism of Traf2 1 0.86 1.04 0.59
131 INT154750 Positive_regulation of Protein_catabolism of Traf2 1 0.60 1.05 0.59
132 INT294555 Negative_regulation of Traf2 1 0.06 1.24 0.58
133 INT269970 Positive_regulation of Positive_regulation of Cd40 2 0.50 1.79 0.57
134 INT83435 Negative_regulation of Binding of CD40LG 2 0.39 0.96 0.55
135 INT236370 Positive_regulation of Phosphorylation of CD40LG 1 0.37 0.59 0.55
136 INT188663 Regulation of Binding of Cd40 1 0.41 0.95 0.55
137 INT190074 Positive_regulation of Traf2 1 0.19 0.37 0.52
138 INT83436 Positive_regulation of Binding of CD40LG 3 0.33 0.85 0.49
139 INT311966 Positive_regulation of Cd40 2 0.50 1.46 0.49
140 INT141194 Regulation of Negative_regulation of Tnf 3 0.42 1.57 0.47
141 INT188800 Protein_catabolism of Traf6 2 0.40 1.6 0.45
142 INT238502 Regulation of CD40 6 0.28 3.7 0.44
143 INT138003 Positive_regulation of Negative_regulation of Tnf 2 0.49 2.07 0.43
144 INT216992 Regulation of Binding of CD40 1 0.13 0.06 0.41
145 INT72086 Regulation of Regulation of Tnf 1 0.45 0.3 0.4
146 INT159782 Phosphorylation of Tnf 2 0.79 1.51 0.36
147 INT217464 Binding of Traf6 5 0.29 1.28 0.35
148 INT143535 Protein_catabolism of Tnf 2 0.86 3.43 0.33
149 INT203075 Positive_regulation of Traf6 1 0.16 0.67 0.32
150 INT188680 Positive_regulation of Binding of Cd40 1 0.46 1.33 0.32
151 INT203074 Positive_regulation of Positive_regulation of Traf6 1 0.16 0.67 0.32
152 INT151274 Negative_regulation of Gene_expression of Cd40lg 3 0.32 2.16 0.3
153 INT116034 Negative_regulation of Transcription of Tnf 2 0.41 0.17 0.29
154 INT153836 Phosphorylation of CD40LG 2 0.79 0.47 0.28
155 INT176333 Transcription of Cd40 1 0.52 0.8 0.28
156 INT5213 Regulation of Localization of Cd40 1 0.26 0 0.27
157 INT217002 Positive_regulation of Localization of CD40 1 0.14 0 0.26
158 INT311985 Regulation of Positive_regulation of Cd40 1 0.45 0.64 0.24
159 INT210927 Positive_regulation of Traf6 4 0.32 0.99 0.22
160 INT194643 Positive_regulation of Regulation of TNF 2 0.28 2.4 0.21
161 INT81351 Negative_regulation of Regulation of TNF 1 0.33 0.23 0.21
162 INT254173 Transcription of Traf6 1 0.25 0.26 0.21
163 INT159783 Positive_regulation of Phosphorylation of Tnf 1 0.12 0.39 0.19
164 INT285263 Positive_regulation of Negative_regulation of Cd40lg 1 0.26 0.34 0.19
165 INT76125 Transcription of CD40LG 5 0.55 2.66 0.18
166 INT219192 Positive_regulation of Regulation of CD40LG 2 0.43 2.9 0.17
167 INT154744 Regulation of Protein_catabolism of Traf2 1 0.39 0.18 0.16
168 INT251578 Positive_regulation of Protein_catabolism of TNF 1 0.41 0.26 0.16
169 INT252316 Regulation of Regulation of Cd40 2 0.24 0.71 0.15
170 INT238504 Positive_regulation of Positive_regulation of CD40 2 0.36 3.03 0.15
171 INT188688 Regulation of Traf6 1 0.24 0.15 0.15
172 INT234680 Localization of Cd40 1 0.18 0.16 0.14
173 INT332303 Localization of Cd40lg 1 0.00 0.26 0.14
174 INT285264 Regulation of Localization of Cd40lg 1 0.25 0.42 0.13
175 INT251559 Binding of Traf2 1 0.23 1.68 0.13
176 INT170142 Regulation of Protein_catabolism of Tnf 1 0.44 1.53 0.13
177 INT219164 Regulation of Positive_regulation of CD40LG 1 0.04 1.51 0.13
178 INT257930 Regulation of Binding of Cd40lg 1 0.13 1.14 0.12
179 INT170592 Regulation of Gene_expression of CD40 4 0.17 0 0.11
180 INT240780 Negative_regulation of Localization of CD40LG 2 0.24 0.72 0.1
181 INT252306 Positive_regulation of Binding of Cd40lg 1 0.22 0.55 0.1
182 INT295324 Regulation of Binding of Tnf 2 0.44 1.11 0.09
183 INT251560 Positive_regulation of Traf2 1 0.13 0.47 0.09
184 INT288014 Negative_regulation of Positive_regulation of CD40 1 0.17 0.63 0.09
185 INT311981 Regulation of Protein_catabolism of Cd40 1 0.45 0.31 0.07
186 INT311983 Protein_catabolism of Cd40 1 0.88 0.31 0.07
187 INT275162 Negative_regulation of Gene_expression of Cd40 1 0.14 1.23 0.06
188 INT285261 Regulation of Positive_regulation of Cd40lg 1 0.15 0.11 0.05
189 INT211878 Transcription of CD40 2 0.35 2.01 0.03
190 INT337233 Positive_regulation of Binding of CD40 1 0.26 0.6 0.03
191 INT159591 Positive_regulation of Binding of Tnf 1 0.43 0.06 0
192 INT298986 Positive_regulation of Gene_expression of Traf6 1 0.23 0.4 0
193 INT222849 Gene_expression of Traf2 1 0.12 0.38 0
194 INT298982 Positive_regulation of Positive_regulation of Traf6 1 0.23 0.4 0
195 INT284542 Negative_regulation of Positive_regulation of Cd40 1 0.27 0.28 0
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