GO:0051045

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Name negative regulation of membrane protein ectodomain proteolysis
Categary Process
Go Slim No
Go Link GO:0051045
Unique Molecular Interactions 433
Total Molecular Interactions 544
Total Single Events 5690
Pain Genes Associated 9

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of membrane protein ectodomain proteolysis. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of membrane protein ectodomain proteolysis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT150889 Il1a Regulation of Il10 1 0.22 3.49 2.95
2 INT70043 IL6 Regulation of IL10 3 0.18 3.59 2.01
3 INT243043 Binding of Mmp9 and Timp1 1 0.05 0.25 1.86
4 INT61134 IL10 Negative_regulation of Gene_expression of IL1B 3 0.46 2.13 1.63
5 INT151849 IL10 Negative_regulation of Gene_expression of IL8 4 0.14 3.26 1.54
6 INT150885 Il6 Regulation of Il10 1 0.22 1.74 1.47
7 INT150887 Il1b Regulation of Il10 1 0.04 1.74 1.47
8 INT178986 Binding of MMP9 and TIMP1 4 0.47 2.58 1.33
9 INT194513 Timp1 Negative_regulation of Cpox 1 0.00 0.9 1.31
10 INT70037 TNF Regulation of IL10 2 0.09 2.11 1.26
11 INT172141 IL10 Negative_regulation of Gene_expression of HLA-DRA 2 0.14 0.89 1.23
12 INT70036 LTA Regulation of Negative_regulation of IL10 1 0.03 1.42 1.21
13 INT70046 IL12A Regulation of IL10 1 0.07 1.42 1.21
14 INT70039 IL1B Regulation of Negative_regulation of IL10 1 0.07 1.42 1.21
15 INT70040 TNF Regulation of Negative_regulation of IL10 1 0.09 1.42 1.21
16 INT70030 IL1B Regulation of IL10 1 0.07 1.42 1.21
17 INT70041 LTA Regulation of IL10 1 0.03 1.42 1.21
18 INT70034 IL12A Regulation of Negative_regulation of IL10 1 0.07 1.42 1.21
19 INT70029 IL6 Regulation of Negative_regulation of IL10 1 0.05 1.42 1.21
20 INT330379 Gene_expression of IL10 Negative_regulation of Positive_regulation of MAPK14 1 0.00 1.95 1.18
21 INT203103 ACAN Negative_regulation of Gene_expression of IL10 1 0.02 1.31 1.12
22 INT267588 IL10 Negative_regulation of Gene_expression of IL6 1 0.01 2.25 1.11
23 INT267597 IL10 Negative_regulation of Gene_expression of TNF 1 0.03 2.24 1.1
24 INT76396 Il10 Negative_regulation of Il1b 2 0.65 1.89 1.08
25 INT139227 Icam1 Negative_regulation of Timp1 1 0.37 1.13 1.06
26 INT292531 Il10 Negative_regulation of Positive_regulation of Mapk14 1 0.15 1.13 1.06
27 INT139231 Calca Negative_regulation of Timp1 1 0.36 1.11 1.05
28 INT228498 Il10 Negative_regulation of Hand1 1 0.03 1.4 0.99
29 INT129215 RYBP Positive_regulation of Il10 1 0.01 1.24 0.98
30 INT292530 Il10 Negative_regulation of Localization of Il1a 1 0.06 1.09 0.97
31 INT129213 RYBP Positive_regulation of Gene_expression of Il10 1 0.01 1.04 0.94
32 INT196523 Binding of MMP2 and TIMP1 3 0.43 1.94 0.85
33 INT226337 Binding of IL10 and IL10RA 2 0.24 2.51 0.85
34 INT113237 Il10 Negative_regulation of Gene_expression of Tacr1 1 0.35 0.81 0.84
35 INT221034 IL10 Positive_regulation of Localization of CCL18 1 0.19 1.3 0.84
36 INT282129 Il10 Positive_regulation of Icam1 1 0.56 3.12 0.82
37 INT187232 Vip Positive_regulation of Gene_expression of Il10 1 0.16 0.95 0.81
38 INT113239 Il10 Regulation of Transcription of Tacr1 1 0.45 0.79 0.81
39 INT228054 Fpr3 Positive_regulation of Il10 1 0.05 0.9 0.79
40 INT130286 MC1R Positive_regulation of Localization of IL10 1 0.24 0.07 0.79
41 INT223753 Tlr4 Positive_regulation of Gene_expression of Il10 4 0.32 1.93 0.78
42 INT184116 Il10 Positive_regulation of Stat3 2 0.18 1.15 0.77
43 INT221415 IRF6 Positive_regulation of Gene_expression of IL10 2 0.05 1.73 0.75
44 INT176473 IL10 Positive_regulation of Gene_expression of PECAM1 1 0.05 1.1 0.75
45 INT150997 Sfpq Positive_regulation of Gene_expression of Il10 1 0.09 0.71 0.74
46 INT176479 IL17A Positive_regulation of Gene_expression of TIMP1 1 0.02 1.33 0.74
47 INT209045 Il10 Positive_regulation of Csf2 1 0.03 0.37 0.72
48 INT209050 Il10 Positive_regulation of Elf1 1 0.10 0.37 0.72
49 INT209041 Il10 Positive_regulation of Ccr1 1 0.01 0.37 0.72
50 INT266765 IL2 Positive_regulation of Localization of IL10 1 0.01 1.03 0.72
51 INT209042 Il10 Positive_regulation of Cxcl1 1 0.07 0.37 0.72
52 INT209044 Il10 Positive_regulation of Il17a 1 0.05 0.37 0.72
53 INT196526 Binding of TIMP1 and TIMP2 1 0.45 1.49 0.71
54 INT187115 Binding of TIMP1 and TNF 2 0.30 1.07 0.7
55 INT194685 MAPK1 Regulation of Gene_expression of IL10 1 0.06 1.18 0.7
56 INT104835 IRF6 Positive_regulation of IL10 4 0.32 0.91 0.69
57 INT172146 IL10 Positive_regulation of Protein_catabolism of TNF 2 0.15 1.69 0.69
58 INT186123 Binding of GIF and IL10 1 0.23 1.17 0.69
59 INT172142 IL10 Positive_regulation of Protein_catabolism of IL1B 2 0.03 1.69 0.68
60 INT231349 Il10 Negative_regulation of Gene_expression of TNF 2 0.23 1.82 0.67
61 INT299282 PTPN3 Negative_regulation of Positive_regulation of RPTOR 1 0.07 0.48 0.67
62 INT214595 Binding of FOXC1 and TIMP1 1 0.02 0.96 0.66
63 INT183387 Il6 Positive_regulation of Gene_expression of Il10 2 0.19 1.8 0.63
64 INT254199 Il10 Positive_regulation of Gene_expression of Socs3 2 0.06 0.75 0.63
65 INT95545 Ptgir Regulation of Gene_expression of Il10 1 0.04 0.97 0.63
66 INT239488 Spna1 Negative_regulation of Gene_expression of Timp1 1 0.00 0.94 0.62
67 INT154530 Positive_regulation of Ifng Negative_regulation of Il10 1 0.33 0.63 0.61
68 INT276598 Il10 Positive_regulation of Gene_expression of Paf 1 0.29 0.49 0.6
69 INT327334 Il10 Negative_regulation of TNF 1 0.02 1.46 0.6
70 INT276597 Paf Positive_regulation of Il10 1 0.27 0.48 0.6
71 INT154531 Ifng Negative_regulation of Il10 1 0.30 0.61 0.6
72 INT276603 Il10 Positive_regulation of Gene_expression of Tlr4 1 0.12 0.49 0.6
73 INT172145 IL10 Negative_regulation of Gene_expression of CSF2 1 0.04 0.69 0.59
74 INT130287 POMC Regulation of Localization of IL10 1 0.12 0.1 0.59
75 INT140890 Il10 Regulation of Il6 1 0.35 0.73 0.58
76 INT181471 Binding of Il10 and Ptbp1 1 0.05 2.14 0.58
77 INT327323 Il10 Positive_regulation of Gene_expression of Ttpa 1 0.02 1.43 0.58
78 INT335995 Il10 Negative_regulation of Tgfb1 1 0.06 0.83 0.57
79 INT239489 Spna1 Negative_regulation of Timp1 1 0.00 0.89 0.57
80 INT175626 TIMP1 Positive_regulation of Gene_expression of MMP9 1 0.03 0.72 0.57
81 INT203105 MMP3 Negative_regulation of Gene_expression of IL10 1 0.06 0.69 0.56
82 INT175627 TIMP1 Positive_regulation of MMP2 1 0.03 0.71 0.56
83 INT173555 TIMP1 Negative_regulation of MMP7 1 0.01 0 0.56
84 INT237205 LGALS4 Positive_regulation of Localization of Il10 1 0.05 0.65 0.56
85 INT173556 TIMP1 Negative_regulation of MMP9 1 0.02 0 0.56
86 INT175623 TIMP1 Positive_regulation of MMP9 1 0.03 0.71 0.56
87 INT173557 TIMP1 Negative_regulation of MMP3 1 0.02 0 0.56
88 INT112025 Binding of Hand1 and Il10 2 0.15 0.56 0.55
89 INT173554 TIMP1 Negative_regulation of MMP1 1 0.03 0 0.55
90 INT173553 TIMP1 Negative_regulation of MMP2 1 0.05 0 0.55
91 INT286349 IRF6 Positive_regulation of Localization of IL10 1 0.03 1.22 0.55
92 INT285758 RETNLB Positive_regulation of Gene_expression of TIMP1 1 0.01 1.79 0.55
93 INT316736 Il1 Positive_regulation of Timp1 1 0.04 0.63 0.54
94 INT351332 Positive_regulation of Il4 Positive_regulation of Gene_expression of Il10 1 0.09 1.78 0.53
95 INT270044 Il10 Positive_regulation of Positive_regulation of Hmox1 1 0.20 1.59 0.53
96 INT196522 Binding of MMP1 and TIMP1 1 0.39 0.29 0.53
97 INT329722 Binding of Il10rb and Il10 1 0.00 0.79 0.51
98 INT329721 Positive_regulation of Binding of Il10rb and Il10 1 0.00 0.79 0.51
99 INT93951 Nfkb1 Regulation of Gene_expression of Timp1 1 0.00 0.26 0.51
100 INT187108 TIMP1 Negative_regulation of ABCA1 1 0.02 0.28 0.51
101 INT271874 IL10 Negative_regulation of TNF 1 0.07 0.78 0.5
102 INT335851 Snrpc Positive_regulation of Il10 1 0.01 1.17 0.5
103 INT116862 Apoe Positive_regulation of Il10 1 0.30 0.69 0.5
104 INT127430 VEGFA Negative_regulation of Gene_expression of TIMP1 1 0.43 0.6 0.5
105 INT194676 Negative_regulation of MAPK1 Negative_regulation of Gene_expression of IL10 1 0.05 0.34 0.5
106 INT285344 Il10 Negative_regulation of Gene_expression of Tnf 1 0.15 1.91 0.49
107 INT185074 Bpifa2 Positive_regulation of Il10 1 0.20 0.84 0.48
108 INT271873 IL10 Regulation of Gene_expression of IK 1 0.00 0.81 0.47
109 INT271872 IL10 Regulation of IK 1 0.00 0.81 0.47
110 INT72088 IL10 Positive_regulation of POMC 1 0.15 0 0.46
111 INT323903 CNDP1 Positive_regulation of IL10 1 0.00 0.9 0.46
112 INT275549 Il10 Positive_regulation of Localization of Hand2 1 0.01 1.3 0.46
113 INT277064 CRP Positive_regulation of Gene_expression of TIMP1 1 0.15 1.47 0.45
114 INT323906 ACCS Positive_regulation of IL10 1 0.05 0.9 0.45
115 INT253075 Prok2 Negative_regulation of Gene_expression of Il10 1 0.24 0.24 0.45
116 INT297694 Positive_regulation of Binding of Il10 and Il13ra1 1 0.01 1.12 0.44
117 INT297696 Binding of Il10 and Il13ra1 1 0.00 1.12 0.43
118 INT352986 IL10 Negative_regulation of Gene_expression of Il6 1 0.01 1 0.43
119 INT316121 IL10 Regulation of Gene_expression of HLA-DRA 1 0.09 0.46 0.42
120 INT181995 TIMP1 Negative_regulation of Mmp9 1 0.01 1.38 0.4
121 INT294780 IL6 Positive_regulation of IL10 2 0.10 1.26 0.39
122 INT321860 Timp1 Negative_regulation of Icam1 1 0.22 1.13 0.39
123 INT303444 Timp1 Regulation of Fig4 1 0.15 0.43 0.39
124 INT233513 Pklr Negative_regulation of Localization of Il10 1 0.04 1.12 0.39
125 INT237415 Il1rn Regulation of Il10 1 0.03 0.96 0.39
126 INT301138 Nsa2 Positive_regulation of Il10 1 0.03 1.22 0.39
127 INT227906 IL10 Regulation of Gene_expression of IL1B 1 0.07 0.57 0.38
128 INT227909 IL10 Regulation of Gene_expression of TNF 1 0.21 0.57 0.38
129 INT335994 Timp1 Regulation of Col7a1 1 0.01 0.36 0.37
130 INT179201 NLRP1 Regulation of Gene_expression of IL10 1 0.06 0.77 0.36
131 INT336339 Glp2r Positive_regulation of Timp1 1 0.16 1.82 0.36
132 INT209047 Slc11a1 Positive_regulation of Localization of Il10 1 0.10 0.52 0.36
133 INT104836 IGKV2OR2-1 Negative_regulation of Gene_expression of IL10 1 0.01 0 0.36
134 INT194641 Binding of IL10 and TNF 2 0.14 1.09 0.35
135 INT198969 GAPDH Negative_regulation of TIMP1 1 0.47 0 0.35
136 INT179845 Il11 Positive_regulation of Negative_regulation of Timp1 1 0.14 0 0.35
137 INT187818 Gene_expression of Il10 Positive_regulation of Gene_expression of Il4 1 0.09 0.69 0.35
138 INT144049 IL10 Negative_regulation of Gene_expression of PTGES 1 0.35 0.47 0.35
139 INT140183 Il4 Positive_regulation of Gene_expression of Il10 1 0.12 0.73 0.34
140 INT97328 Ptger2 Regulation of Transcription of Timp1 1 0.00 0.48 0.34
141 INT336336 Il10 Regulation of Il13 1 0.04 0.67 0.34
142 INT224701 Timp3 Negative_regulation of TNF 1 0.01 0.65 0.34
143 INT184095 Il10 Positive_regulation of Socs3 1 0.21 0.49 0.34
144 INT140181 Gene_expression of Il4 Positive_regulation of Gene_expression of Il10 1 0.17 0.73 0.34
145 INT97357 IL1A Positive_regulation of Transcription of Timp1 1 0.06 0.47 0.34
146 INT112021 Binding of Il10 and IgG2a 1 0.07 0.31 0.33
147 INT112023 Binding of Ifng and Il10 1 0.03 0.31 0.33
148 INT266806 Hand2 Regulation of Gene_expression of IL10 1 0.00 1.23 0.32
149 INT254218 Binding of Il10 and Il10rb 1 0.00 0.87 0.32
150 INT254226 Binding of Il10 and Il10ra 1 0.00 0.87 0.32
151 INT316488 Il22 Positive_regulation of Il10 1 0.29 0.63 0.32
152 INT204792 Tnbs1 Positive_regulation of Transcription of Il10 1 0.09 1.2 0.32
153 INT307019 MT1JP Positive_regulation of Gene_expression of IL10 1 0.03 0.58 0.32
154 INT303446 Timp1 Negative_regulation of Mmp2 1 0.19 0.33 0.31
155 INT97327 Ptger2 Positive_regulation of Gene_expression of Timp1 1 0.00 0.46 0.31
156 INT97358 IL1A Regulation of Timp1 1 0.04 0.51 0.31
157 INT316483 Il22ra1 Positive_regulation of Il10 1 0.27 0.62 0.31
158 INT97326 Ptger2 Positive_regulation of Transcription of Timp1 1 0.00 0.49 0.31
159 INT76397 Il10 Negative_regulation of Ngf 1 0.44 0.45 0.3
160 INT76395 Il10 Negative_regulation of Gene_expression of Ngf 1 0.45 0.45 0.3
161 INT254206 Il10 Negative_regulation of Chuk 1 0.05 0.59 0.29
162 INT271350 MPO Positive_regulation of TIMP1 1 0.05 1.66 0.29
163 INT335307 SLC15A4 Regulation of TIMP1 1 0.01 0.69 0.29
164 INT227910 TNF Positive_regulation of Gene_expression of IL10 1 0.22 0.68 0.29
165 INT302467 TIMP1 Positive_regulation of Negative_regulation of COL5A2 1 0.00 1.1 0.29
166 INT319753 Mpo Positive_regulation of Timp1 1 0.14 2.13 0.29
167 INT254208 Il10 Negative_regulation of Regulation of Chuk 1 0.05 0.59 0.29
168 INT55682 IL1B Positive_regulation of TIMP1 2 0.46 0.17 0.28
169 INT218709 Mmp1a Negative_regulation of TIMP1 1 0.00 1.84 0.28
170 INT178102 EDNRA Positive_regulation of Localization of TIMP1 1 0.06 0.97 0.28
171 INT178088 EDNRA Positive_regulation of Transcription of TIMP1 1 0.06 0.97 0.28
172 INT275548 Il10 Regulation of Mmp9 1 0.00 0.86 0.28
173 INT55683 IL1B Positive_regulation of Gene_expression of TIMP1 1 0.64 0.17 0.28
174 INT55681 IL1B Regulation of Gene_expression of TIMP1 1 0.56 0.18 0.28
175 INT275556 Il10 Positive_regulation of Gene_expression of TIMP1 1 0.00 0.85 0.28
176 INT282128 Gene_expression of Il10 Positive_regulation of Positive_regulation of Icam1 1 0.37 1.12 0.28
177 INT218660 Mmp1a Negative_regulation of Timp1 1 0.02 1.84 0.28
178 INT275509 IL8 Positive_regulation of Gene_expression of TIMP1 1 0.00 0.85 0.28
179 INT194682 Negative_regulation of MAPK1 Positive_regulation of Gene_expression of IL10 1 0.05 0.17 0.27
180 INT262809 Il10 Positive_regulation of Regulation of Slc11a1 1 0.17 1.12 0.27
181 INT251567 Il4 Negative_regulation of Gene_expression of Il10 1 0.01 0.96 0.27
182 INT220870 Timp3 Negative_regulation of Adamts4 1 0.03 0.15 0.27
183 INT172140 CSF2 Positive_regulation of Gene_expression of TIMP1 1 0.07 0.72 0.27
184 INT220871 Timp3 Negative_regulation of Adamts1 1 0.01 0.15 0.27
185 INT262810 Slc11a1 Positive_regulation of Gene_expression of Il10 1 0.20 0.97 0.27
186 INT34231 PTGER2 Positive_regulation of Gene_expression of TIMP1 1 0.13 0.23 0.27
187 INT333763 Il27 Positive_regulation of Gene_expression of Il10 2 0.22 0.8 0.26
188 INT120856 PRL Positive_regulation of Localization of IL10 1 0.29 0.5 0.26
189 INT328064 IL10 Positive_regulation of FAAH 1 0.05 1.48 0.26
190 INT136367 RYBP Negative_regulation of Positive_regulation of Il10 1 0.00 0.37 0.26
191 INT226361 Binding of IL10 and IL22RA1 1 0.00 0.17 0.26
192 INT254283 Il10 Negative_regulation of Nfatc1 1 0.02 0.31 0.25
193 INT203165 Binding of IL10 and PTGER2 1 0.01 0.5 0.25
194 INT178141 EDN1 Positive_regulation of Timp1 1 0.30 0.89 0.24
195 INT260743 Mapk14 Regulation of Gene_expression of Il10 1 0.04 0.99 0.24
196 INT178104 EDN1 Positive_regulation of Localization of TIMP1 1 0.05 0.83 0.24
197 INT277066 MMP1 Positive_regulation of Gene_expression of TIMP1 1 0.16 0.76 0.24
198 INT178142 EDN1 Positive_regulation of Localization of Timp1 1 0.28 0.89 0.24
199 INT186368 Il10 Negative_regulation of Gene_expression of Il12a 1 0.06 0.17 0.24
200 INT113419 IL10 Negative_regulation of Gene_expression of IL18 1 0.31 0.86 0.24

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of membrane protein ectodomain proteolysis. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of membrane protein ectodomain proteolysis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT60694 Gene_expression of Il10 567 0.78 369.48 143.69
2 INT48895 Gene_expression of Il10 333 0.78 221.2 138.52
3 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84
4 INT1759 Gene_expression of TIMP1 267 0.77 133.87 59.29
5 INT48891 Positive_regulation of Il10 143 0.70 101.42 56.72
6 INT63975 Positive_regulation of Il10 175 0.68 134.13 54.69
7 INT73502 Positive_regulation of IL10 154 0.69 124.87 43.5
8 INT60695 Positive_regulation of Gene_expression of Il10 154 0.70 120.28 43.07
9 INT12892 Negative_regulation of TIMP1 136 0.58 83.13 36.54
10 INT48896 Positive_regulation of Gene_expression of Il10 73 0.70 43.14 35.5
11 INT90792 Localization of Il10 144 0.80 87.88 30.03
12 INT59449 Negative_regulation of Timp1 76 0.42 54.86 26.99
13 INT70048 Positive_regulation of Gene_expression of IL10 90 0.55 71.34 25.66
14 INT72370 Gene_expression of Timp1 82 0.65 57.52 24.16
15 INT74423 Localization of IL10 91 0.80 61.6 22.95
16 INT86751 Negative_regulation of Il10 62 0.59 40.1 20.51
17 INT51055 Positive_regulation of TIMP1 103 0.69 50.07 19.86
18 INT69304 Negative_regulation of Il10 47 0.59 36.88 19.79
19 INT74286 Regulation of Il10 42 0.44 28.06 19.44
20 INT72564 Localization of Il10 41 0.78 28.62 17.6
21 INT48892 Transcription of Il10 31 0.71 27.26 16.77
22 INT1758 Positive_regulation of Gene_expression of TIMP1 62 0.69 31.72 13.98
23 INT55740 Gene_expression of Timp1 53 0.75 28.63 13.85
24 INT86950 Negative_regulation of Gene_expression of Il10 26 0.42 18.92 12.73
25 INT70050 Negative_regulation of IL10 56 0.58 37.45 12.39
26 INT55687 Localization of TIMP1 47 0.74 30.24 12.31
27 INT79835 Regulation of Il10 28 0.61 21.22 11.29
28 INT71766 Transcription of Il10 31 0.69 24.66 10.78
29 INT71768 Regulation of Gene_expression of Il10 27 0.62 19.17 10.4
30 INT71769 Negative_regulation of Gene_expression of Il10 40 0.57 22.53 10.37
31 INT81929 Negative_regulation of Gene_expression of IL10 41 0.57 27.99 9.87
32 INT73497 Regulation of IL10 33 0.45 22.6 9.19
33 INT111397 Localization of Timp1 17 0.70 11.67 8.76
34 INT97331 Positive_regulation of Timp1 20 0.45 13.32 8.57
35 INT96068 Positive_regulation of Timp1 30 0.58 23.94 8.17
36 INT36678 Binding of TIMP1 33 0.36 14.99 7.87
37 INT103289 Binding of Il10 15 0.35 13.67 7.42
38 INT91906 Regulation of Gene_expression of Il10 13 0.58 8.92 7.06
39 INT21579 Negative_regulation of Gene_expression of TIMP1 25 0.57 12.41 6.94
40 INT60527 Transcription of IL10 16 0.56 13.57 6.42
41 INT34232 Regulation of TIMP1 37 0.61 18.76 6.05
42 INT173974 Positive_regulation of Localization of Il10 25 0.68 16.81 5.87
43 INT109124 Positive_regulation of TIMP3 8 0.61 5.57 5.72
44 INT187133 Protein_catabolism of TIMP1 19 0.73 11.3 5.51
45 INT126751 Regulation of Gene_expression of IL10 16 0.44 10.84 5.22
46 INT245593 Gene_expression of PTPN3 32 0.38 10.68 5.09
47 INT142162 Binding of IL10 30 0.37 21.9 4.84
48 INT21582 Regulation of Gene_expression of TIMP1 20 0.61 12.39 4.77
49 INT130290 Positive_regulation of Localization of IL10 16 0.47 9.38 4.75
50 INT71767 Positive_regulation of Transcription of Il10 10 0.67 5.55 4.66
51 INT97334 Positive_regulation of Gene_expression of Timp1 11 0.49 7.44 4.14
52 INT55741 Negative_regulation of Timp1 15 0.51 8.12 4.09
53 INT189629 Negative_regulation of TIMP3 14 0.48 7.63 3.91
54 INT194846 Positive_regulation of Positive_regulation of Il10 9 0.57 5.07 3.71
55 INT74157 Negative_regulation of Positive_regulation of Il10 5 0.43 5.83 3.56
56 INT89521 Positive_regulation of Localization of Il10 8 0.44 6.45 3.51
57 INT93947 Regulation of Gene_expression of Timp1 5 0.25 5.04 3.42
58 INT194848 Negative_regulation of Localization of Il10 11 0.36 8.29 3.38
59 INT48893 Positive_regulation of Transcription of Il10 3 0.69 4.29 3.29
60 INT55690 Positive_regulation of Localization of TIMP1 8 0.50 4.77 3.28
61 INT230060 Binding of Timp1 7 0.47 5.61 3.2
62 INT130603 Binding of Timp1 9 0.35 8.52 3.04
63 INT55739 Transcription of Timp1 7 0.67 4.72 3
64 INT115579 Positive_regulation of Positive_regulation of Il10 7 0.68 4.82 2.91
65 INT104476 Protein_catabolism of Timp1 6 0.41 5.75 2.61
66 INT175685 Positive_regulation of Gene_expression of Timp1 11 0.57 8.18 2.58
67 INT90791 Regulation of Localization of Il10 6 0.44 2.94 2.5
68 INT48894 Negative_regulation of Transcription of Il10 5 0.26 2.79 2.22
69 INT127740 Regulation of Localization of Il10 3 0.60 0.65 2.18
70 INT158459 Negative_regulation of Gene_expression of Timp1 8 0.40 4.21 2.16
71 INT173509 Positive_regulation of Localization of Timp1 5 0.41 2.99 2.04
72 INT169352 Negative_regulation of Timp3 10 0.58 6.94 1.92
73 INT160241 Negative_regulation of Positive_regulation of Il10 6 0.39 6.33 1.92
74 INT102825 Regulation of Timp1 10 0.38 5.49 1.79
75 INT223746 Binding of Il10 12 0.36 9.49 1.73
76 INT97333 Regulation of Gene_expression of Timp1 6 0.54 4.8 1.71
77 INT98469 Positive_regulation of Transcription of Timp1 4 0.45 3.2 1.68
78 INT269828 Transcription of Timp1 3 0.38 5.2 1.53
79 INT53131 Transcription of TIMP1 8 0.68 3.89 1.5
80 INT262908 Negative_regulation of Localization of IL10 5 0.43 4 1.5
81 INT194854 Regulation of Positive_regulation of Il10 3 0.37 2.55 1.44
82 INT113268 Positive_regulation of Positive_regulation of Timp1 3 0.15 3.23 1.43
83 INT103755 Positive_regulation of Negative_regulation of Il10 3 0.49 2.64 1.4
84 INT97332 Regulation of Timp1 4 0.44 3.6 1.38
85 INT345377 Positive_regulation of Positive_regulation of TIMP3 1 0.37 0.09 1.29
86 INT245598 Positive_regulation of PTPN3 3 0.34 1.13 1.23
87 INT182847 Regulation of Binding of Il10 2 0.41 1.26 1.15
88 INT107198 Negative_regulation of Transcription of Il10 3 0.38 4.19 1.14
89 INT233286 Positive_regulation of Timp3 1 0.02 1.46 1.1
90 INT159775 Negative_regulation of Gene_expression of Timp1 9 0.37 4.36 1.08
91 INT164533 Positive_regulation of Regulation of Il10 4 0.46 2.09 1.06
92 INT91907 Positive_regulation of Negative_regulation of Il10 2 0.48 1.37 1
93 INT172176 Regulation of Regulation of TIMP1 1 0.20 2.33 0.97
94 INT110739 Negative_regulation of Negative_regulation of TIMP1 4 0.41 3.29 0.95
95 INT103758 Negative_regulation of Negative_regulation of Il10 1 0.41 0 0.95
96 INT74424 Regulation of Localization of IL10 3 0.31 0.91 0.93
97 INT295679 Regulation of Localization of TIMP1 1 0.17 2.7 0.93
98 INT316726 Regulation of Localization of Timp1 1 0.15 0.81 0.92
99 INT171008 Positive_regulation of Transcription of IL10 1 0.15 1.33 0.89
100 INT134753 Gene_expression of TIMP3 19 0.68 15.24 0.88
101 INT178987 Positive_regulation of Positive_regulation of TIMP1 5 0.20 2.81 0.83
102 INT245596 Positive_regulation of Gene_expression of PTPN3 5 0.25 0.92 0.79
103 INT104475 Regulation of Protein_catabolism of Timp1 1 0.00 0.61 0.79
104 INT182059 Positive_regulation of Positive_regulation of IL10 3 0.17 1.86 0.77
105 INT34233 Regulation of Negative_regulation of TIMP1 3 0.27 0.48 0.77
106 INT134752 Negative_regulation of Gene_expression of TIMP3 5 0.37 2.25 0.73
107 INT51053 Negative_regulation of Positive_regulation of TIMP1 6 0.35 1.67 0.69
108 INT55689 Positive_regulation of Transcription of TIMP1 3 0.46 1.02 0.67
109 INT327768 Regulation of Transcription of IL10 1 0.17 0.13 0.61
110 INT153940 Localization of Timp1 3 0.78 0.63 0.55
111 INT213154 Positive_regulation of Binding of TIMP1 2 0.41 1.33 0.55
112 INT276928 Phosphorylation of Il10 4 0.58 1.74 0.49
113 INT303453 Negative_regulation of Binding of Timp1 1 0.41 1.44 0.49
114 INT303455 Regulation of Binding of Timp1 1 0.44 1.21 0.48
115 INT173583 Negative_regulation of Binding of TIMP1 1 0.13 0 0.48
116 INT180920 Positive_regulation of Positive_regulation of Timp1 2 0.38 1.59 0.46
117 INT110738 Positive_regulation of Negative_regulation of TIMP1 4 0.44 0.44 0.45
118 INT311099 Positive_regulation of Negative_regulation of TIMP3 2 0.22 0.78 0.45
119 INT323141 Positive_regulation of Negative_regulation of IL10 1 0.37 1.06 0.44
120 INT184444 Binding of Timp3 3 0.47 0.25 0.41
121 INT150095 Regulation of Positive_regulation of TIMP1 2 0.44 0.76 0.41
122 INT181987 Negative_regulation of Negative_regulation of Timp1 1 0.23 1.39 0.41
123 INT352983 Protein_catabolism of IL10 1 0.13 1.04 0.41
124 INT245599 Regulation of Gene_expression of PTPN3 1 0.22 0.57 0.41
125 INT189030 Phosphorylation of PTPN3 3 0.31 1.17 0.39
126 INT279364 Regulation of Negative_regulation of IL10 1 0.04 0.49 0.39
127 INT279367 Negative_regulation of Regulation of IL10 1 0.06 0.49 0.39
128 INT245591 Negative_regulation of Gene_expression of PTPN3 2 0.21 0.44 0.35
129 INT275517 Positive_regulation of Binding of Il10 1 0.08 1.06 0.33
130 INT245595 Localization of PTPN3 1 0.39 0.67 0.29
131 INT245592 Regulation of PTPN3 3 0.22 0.88 0.28
132 INT114603 Negative_regulation of Localization of Il10 1 0.21 0.61 0.28
133 INT299798 Negative_regulation of Transcription of IL10 1 0.07 0.73 0.27
134 INT233398 Localization of TIMP3 2 0.45 1.31 0.26
135 INT156686 Negative_regulation of Localization of TIMP1 2 0.35 1.29 0.22
136 INT341658 Negative_regulation of Regulation of TIMP1 1 0.33 0.91 0.21
137 INT245597 Positive_regulation of Localization of PTPN3 1 0.34 0.07 0.21
138 INT182061 Regulation of Positive_regulation of IL10 1 0.12 1.07 0.18
139 INT189564 Binding of TIMP3 4 0.31 2.45 0.17
140 INT189039 Negative_regulation of PTPN3 3 0.21 1.01 0.16
141 INT231956 Phosphorylation of IL10 1 0.26 0.07 0.16
142 INT310587 Positive_regulation of Negative_regulation of Timp1 1 0.44 0.81 0.14
143 INT104841 Negative_regulation of Positive_regulation of IL10 1 0.27 0 0.14
144 INT245594 Positive_regulation of Positive_regulation of PTPN3 1 0.23 0.42 0.13
145 INT219179 Positive_regulation of Regulation of IL10 1 0.08 0.45 0.13
146 INT248410 Negative_regulation of Regulation of Il10 1 0.27 0.38 0.11
147 INT321857 Phosphorylation of Timp1 1 0.61 0.76 0.1
148 INT321859 Negative_regulation of Phosphorylation of Timp1 1 0.32 0.76 0.1
149 INT351074 Negative_regulation of Binding of Timp1 1 0.04 1.14 0.09
150 INT339391 Regulation of Positive_regulation of Il10 1 0.26 0.31 0.09
151 INT335988 Protein_catabolism of Il10 1 0.61 0.1 0.05
152 INT227010 Regulation of TIMP3 3 0.62 1.72 0.03
153 INT189570 Positive_regulation of Gene_expression of TIMP3 3 0.44 1.57 0
154 INT299355 Binding of PTPN3 2 0.10 0.07 0
155 INT299345 Positive_regulation of Binding of PTPN3 1 0.09 0.07 0
156 INT299135 Regulation of Positive_regulation of Timp1 1 0.26 0.26 0
157 INT189032 Positive_regulation of Phosphorylation of PTPN3 1 0.06 0.36 0
158 INT355686 Regulation of Transcription of Il10 1 0.12 0 0
159 INT347143 Gene_expression of Timp3 1 0.73 0 0
160 INT152258 Regulation of Transcription of Il10 1 0.07 0.11 0
161 INT248345 Regulation of Binding of IL10 1 0.45 0.78 0
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