GO:0051048

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Name negative regulation of secretion
Categary Process
Go Slim No
Go Link GO:0051048
Unique Molecular Interactions 264
Total Molecular Interactions 373
Total Single Events 1783
Pain Genes Associated 9

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of secretion. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of secretion. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT356289 Binding of Egfr and Egf 1 0.13 3.02 2.52
2 INT220751 EGF Regulation of GOPC 1 0.08 0 1.18
3 INT220752 Negative_regulation of EGF Regulation of NAV1 1 0.26 0 1.18
4 INT220753 Negative_regulation of EGF Regulation of GOPC 1 0.08 0 1.18
5 INT220748 EGF Regulation of NAV1 1 0.28 0 1.17
6 INT136989 EGF Negative_regulation of Positive_regulation of KCNJ2 1 0.04 1.09 1.1
7 INT87222 Nrg1 Regulation of Oprd1 1 0.00 0 1.07
8 INT136988 EGF Negative_regulation of KCNJ2 1 0.04 1.09 1.04
9 INT72386 Egf Positive_regulation of Phosphorylation of Shc1 1 0.09 0.18 0.93
10 INT118288 EGF Positive_regulation of Phosphorylation of EGFR 9 0.54 3.85 0.9
11 INT220744 EGF Positive_regulation of Gene_expression of KRT20 1 0.01 1.26 0.9
12 INT134454 EGF Positive_regulation of EGFR 3 0.56 1.32 0.88
13 INT134453 Negative_regulation of EGF Positive_regulation of EGFR 1 0.35 0.35 0.88
14 INT220739 EGF Positive_regulation of Transcription of NAV1 1 0.31 0.16 0.83
15 INT84039 EGF Positive_regulation of Gene_expression of CPOX 2 0.11 1.88 0.8
16 INT84040 EGF Positive_regulation of CPOX 2 0.07 1.91 0.8
17 INT220747 Binding of PCa and EGF 1 0.05 1.42 0.8
18 INT42797 Egf Regulation of Gene_expression of Penk 1 0.21 0.07 0.8
19 INT108331 EGF Positive_regulation of Phosphorylation of BAD 1 0.49 6.72 0.8
20 INT231031 Egf Positive_regulation of Sec22b 1 0.03 0.05 0.76
21 INT220746 EGF Positive_regulation of Gene_expression of GOPC 1 0.13 0 0.72
22 INT220738 EGF Regulation of Gene_expression of EGFR 1 0.09 0.6 0.67
23 INT169287 EGF Positive_regulation of Localization of IL8 1 0.15 0.13 0.61
24 INT169294 EGF Positive_regulation of Localization of IL6 1 0.18 0.13 0.61
25 INT100225 Binding of Egf and Src 1 0.01 0.67 0.58
26 INT199976 EGF Regulation of ITGB3BP 1 0.02 0.77 0.57
27 INT121994 EGF Positive_regulation of Positive_regulation of MAPK1 1 0.25 0 0.55
28 INT121993 Binding of EGF and SGCG 1 0.40 0 0.55
29 INT220745 EGF Positive_regulation of Positive_regulation of PCa 1 0.05 0.79 0.52
30 INT98735 Src Negative_regulation of Egf 1 0.26 0.15 0.5
31 INT98734 Egf Negative_regulation of Tk1 1 0.13 0.15 0.49
32 INT295708 Binding of EGF and CCL2 1 0.01 0.79 0.49
33 INT108329 EGF Positive_regulation of Phosphorylation of EPHB2 4 0.48 3.96 0.48
34 INT108332 EGF Positive_regulation of Phosphorylation of MAPK1 5 0.48 1.85 0.45
35 INT295406 Egf Regulation of Gene_expression of Oprk1 1 0.01 0.72 0.43
36 INT311590 EGF Regulation of Gene_expression of CXCL10 1 0.23 0.51 0.43
37 INT311589 EGF Regulation of Gene_expression of VEGFA 1 0.18 0.51 0.43
38 INT311591 CXCL10 Regulation of Gene_expression of EGF 1 0.23 0.51 0.43
39 INT13281 Egf Regulation of Ngf 1 0.66 0.12 0.42
40 INT13279 Ngf Regulation of Egf 1 0.49 0.12 0.42
41 INT13283 Egf Regulation of Fgf2 1 0.49 0.11 0.41
42 INT13284 Fgf2 Regulation of Egf 1 0.49 0.11 0.41
43 INT90807 EGF Positive_regulation of Oprd1 1 0.00 0.39 0.39
44 INT283840 Binding of Egf and hb 1 0.21 1.34 0.38
45 INT356274 Egf Positive_regulation of Localization of Stat3 1 0.13 0.22 0.36
46 INT295407 Egf Positive_regulation of Localization of Oprk1 1 0.02 0.67 0.36
47 INT94875 Binding of Calca and Egf 1 0.25 0 0.35
48 INT188193 Negative_regulation of EGF Positive_regulation of MAPK1 1 0.28 0.54 0.34
49 INT156831 EGF Positive_regulation of MAPK1 2 0.45 0.27 0.33
50 INT220740 EGF Positive_regulation of Regulation of NAV1 1 0.31 0.61 0.32
51 INT220749 EGF Positive_regulation of Positive_regulation of KRT20 1 0.01 0.61 0.32
52 INT299549 Binding of TGFB1 and Egf 1 0.02 0.32 0.32
53 INT75769 Egf Positive_regulation of Cpox 1 0.26 0.76 0.31
54 INT170496 Egf Positive_regulation of Mapk1 3 0.21 0.5 0.3
55 INT356288 Egf Positive_regulation of Trib3 1 0.00 0.17 0.3
56 INT303440 Egf Positive_regulation of Gene_expression of Col7a1 1 0.07 0.92 0.28
57 INT193027 EGF Positive_regulation of Positive_regulation of MRGPRX1 1 0.02 0 0.27
58 INT285243 EGF Positive_regulation of Egf 1 0.00 1.55 0.27
59 INT285238 EGF Positive_regulation of VEGFA 1 0.01 1.55 0.27
60 INT144255 EGF Regulation of Positive_regulation of NFKB1 1 0.41 0.66 0.27
61 INT195898 Negative_regulation of Egf Negative_regulation of Gene_expression of Cpox 1 0.03 0.3 0.26
62 INT171384 Egf Negative_regulation of Positive_regulation of Mapk1 1 0.16 0.24 0.26
63 INT141634 Binding of Alb and Nrg1 1 0.00 0.3 0.26
64 INT134522 Nrg1 Regulation of Gene_expression of Mpz 1 0.60 0.29 0.25
65 INT332242 Binding of Egf and Pdgfa 1 0.07 0.97 0.25
66 INT134523 Nrg1 Positive_regulation of Gene_expression of Mpz 1 0.49 0.32 0.23
67 INT9720 Binding of TGFB1 and Egf 1 0.01 0 0.23
68 INT220750 EGF Positive_regulation of PCa 1 0.05 0.45 0.23
69 INT173294 LPA Positive_regulation of EGF 1 0.01 0.07 0.23
70 INT173292 F2 Positive_regulation of EGF 1 0.00 0.07 0.23
71 INT9717 Binding of Egf and Fgfr1 1 0.15 0 0.22
72 INT9716 Binding of Egf and Pdgfc 1 0.20 0 0.22
73 INT193033 Binding of CHRM1 and EGF 1 0.01 1.96 0.22
74 INT9718 Binding of Egf and Ngf 1 0.30 0 0.21
75 INT193035 Positive_regulation of PDGFA Positive_regulation of EGF 1 0.05 0.53 0.21
76 INT188203 EGF Positive_regulation of Protein_catabolism of OSM 1 0.30 0.17 0.21
77 INT9715 Binding of Egf and Tgfa 1 0.18 0 0.21
78 INT112136 Egf Positive_regulation of Gene_expression of Ptgs2 1 0.21 0.19 0.21
79 INT78263 Npy Positive_regulation of Npy2r 1 0.04 0 0.21
80 INT193025 PDGFA Positive_regulation of EGF 1 0.05 0.53 0.21
81 INT193036 EGF Positive_regulation of PDGFA 1 0.05 0.53 0.21
82 INT193032 Positive_regulation of EGF Positive_regulation of PDGFA 1 0.05 0.53 0.21
83 INT326575 Nrg1 Positive_regulation of Gene_expression of JUN 1 0.38 0.86 0.2
84 INT145152 Binding of EGF and EGFR 4 0.15 2.45 0.19
85 INT14869 Binding of EGF and TGFB3 1 0.14 0.69 0.19
86 INT23655 Binding of POMC and Egf 1 0.04 0 0.19
87 INT332247 Egf Positive_regulation of Stat6 1 0.13 1.23 0.19
88 INT186098 EGF Positive_regulation of MAP2K5 1 0.01 0.19 0.18
89 INT274168 Egf Positive_regulation of Gene_expression of Muc5ac 1 0.01 2.11 0.17
90 INT261477 Egf Positive_regulation of Positive_regulation of Ephb1 1 0.37 0.21 0.17
91 INT24668 Binding of COL7A1 and EGF 1 0.14 0.25 0.16
92 INT117137 Gene_expression of ROS1 Positive_regulation of Protein_catabolism of Egf 1 0.00 0 0.16
93 INT231274 Nrg1 Regulation of Gene_expression of Akt1 1 0.19 0 0.14
94 INT238329 EGF Regulation of Negative_regulation of ADAMTS5 1 0.03 0 0.14
95 INT238338 Binding of EGF and Regulation of Gene_expression of GOPC 1 0.05 0 0.14
96 INT238337 EGF Regulation of Gene_expression of GOPC 1 0.03 0 0.14
97 INT238342 Binding of EGF and Regulation of Gene_expression of ADAMTS1 1 0.05 0 0.14
98 INT356285 Binding of Stat3 and Egf 1 0.09 0.4 0.13
99 INT73924 EGF Positive_regulation of Localization of COL7A1 1 0.31 0.33 0.13
100 INT253015 Egf Regulation of PTTG1 1 0.02 0.44 0.13
101 INT108330 EGF Negative_regulation of EPHB2 1 0.41 1.15 0.13
102 INT299547 Negative_regulation of Binding of TGFB1 and Egf 1 0.02 0.1 0.13
103 INT279799 ATP6V0A2 Regulation of ERBB3 1 0.00 1.77 0.12
104 INT195896 Egf Positive_regulation of Nos1 1 0.10 0.57 0.12
105 INT356276 Egf Positive_regulation of Positive_regulation of Mapk1 1 0.05 0.52 0.12
106 INT211996 Erbb3 Positive_regulation of Nrg1 2 0.03 0.67 0.11
107 INT299551 Regulation of Binding of TGFB1 and Egf 1 0.03 0.21 0.11
108 INT146937 Egf Regulation of Trpm6 1 0.03 0.27 0.11
109 INT287267 EGF Positive_regulation of CDC42 1 0.12 0.16 0.11
110 INT156829 EGF Positive_regulation of MAPK3 2 0.08 0.87 0.1
111 INT356272 Egf Negative_regulation of Gene_expression of Egfr 1 0.15 0.2 0.1
112 INT222553 Binding of Sdc1 and Egf 1 0.02 0 0.1
113 INT286963 EGF Positive_regulation of Gene_expression of STAT3 1 0.03 0.57 0.1
114 INT231273 Binding of Egfr and Nrg1 1 0.12 0 0.09
115 INT341008 Nrg1 Regulation of Binding of Erbb4 1 0.04 0 0.09
116 INT54096 NRG1 Regulation of Protein_catabolism of Fgg 1 0.01 0 0.09
117 INT250661 Binding of EGF and ERBB2 2 0.11 0.82 0.08
118 INT27109 Egf Regulation of Gast 1 0.42 0 0.08
119 INT110856 TXK Negative_regulation of Egf 1 0.02 1.2 0.08
120 INT309903 Binding of EGF and TXK 1 0.03 0.23 0.08
121 INT110855 Pkia Negative_regulation of Egf 1 0.15 1.2 0.08
122 INT222139 Binding of Egf and Fgf2 1 0.12 0 0.07
123 INT188210 EGF Positive_regulation of OSM 1 0.28 0 0.07
124 INT188208 EGF Regulation of STAT3 1 0.46 0 0.07
125 INT299535 Binding of Egf and Lif 1 0.07 0 0.07
126 INT246539 EGF Negative_regulation of Gene_expression of PDGFA 1 0.06 0.38 0.07
127 INT246538 PDGFA Negative_regulation of Gene_expression of EGF 1 0.06 0.38 0.07
128 INT24666 Binding of EGF and FGF2 1 0.35 0 0.06
129 INT225262 Egf Regulation of Gene_expression of S100a7a 1 0.04 3.31 0.06
130 INT317245 Binding of Npy2r and Pyy 1 0.09 0 0.05
131 INT338019 Egf Positive_regulation of AR 1 0.07 1.02 0.05
132 INT27738 CBS Positive_regulation of EGF 1 0.33 0.85 0.05
133 INT225261 S100a7a Positive_regulation of Egf 1 0.07 1.13 0.05
134 INT27737 CBS Positive_regulation of Positive_regulation of EGF 1 0.36 0.85 0.05
135 INT317246 Binding of Npy2r and Npy 1 0.08 0 0.05
136 INT295337 Egf Positive_regulation of Ptpn11 1 0.15 0.08 0.05
137 INT186097 EGF Positive_regulation of Positive_regulation of EGFR 1 0.20 0.38 0.04
138 INT295358 Egf Positive_regulation of Ddr1 1 0.03 0.1 0.04
139 INT341009 Nrg1 Positive_regulation of Gene_expression of Fabp7 1 0.10 0.49 0.04
140 INT231276 Erbb4 Positive_regulation of Nrg1 2 0.35 0.06 0.03
141 INT316057 Binding of Erbb4 and Nrg1 2 0.03 0.38 0.03
142 INT295352 Egf Positive_regulation of Grb7 1 0.42 0.06 0.03
143 INT316061 Positive_regulation of Binding of Erbb4 and Nrg1 1 0.03 0.38 0.03
144 INT295351 Egf Positive_regulation of Fig4 1 0.12 0.06 0.03
145 INT356277 Egf Positive_regulation of Phosphorylation of Mapk1 1 0.07 0.33 0.03
146 INT231275 Erbb4 Positive_regulation of Gene_expression of Nrg1 1 0.35 0 0.03
147 INT346331 Binding of Epo and Egf 1 0.19 0.1 0.03
148 INT334869 Nrg1 Positive_regulation of Phosphorylation of C3 1 0.08 0 0.03
149 INT213559 Binding of Egf and Shh 1 0.17 0.07 0.03
150 INT295343 Negative_regulation of Egf Positive_regulation of Grb7 1 0.38 0.06 0.03
151 INT287268 Binding of ERBB2 and ERBB3 5 0.16 2.74 0
152 INT295412 Egf Regulation of Transcription of Oprk1 1 0.01 0 0
153 INT285071 EGF Positive_regulation of CCL16 1 0.03 0.77 0
154 INT225258 Egf Positive_regulation of Gene_expression of S100a7a 1 0.07 1.7 0
155 INT226732 Egf Negative_regulation of Egfr 1 0.01 0.15 0
156 INT314772 Binding of Egf and Gast 1 0.02 0.62 0
157 INT353544 Egf Regulation of Gene_expression of ONECUT1 1 0.00 0.08 0
158 INT353540 Egf Positive_regulation of Hgf 1 0.23 0.08 0
159 INT279802 ATP6V0A2 Negative_regulation of ERBB3 1 0.00 1.96 0
160 INT341005 Binding of Vim and Nrg1 1 0.05 0.14 0
161 INT299554 CLTCL1 Regulation of Gene_expression of Egf 1 0.00 0.16 0
162 INT293801 EGF Positive_regulation of EPHB2 1 0.11 0 0
163 INT186096 EGF Regulation of Positive_regulation of CASP3 1 0.01 0.28 0
164 INT327101 Binding of AREG and EGF 1 0.05 0.35 0
165 INT227670 EGF Positive_regulation of Gene_expression of ISYNA1 1 0.01 2.92 0
166 INT265604 Egf Positive_regulation of Gene_expression of Hgf 1 0.14 0.46 0
167 INT335215 RDH5 Positive_regulation of Negative_regulation of ERBB3 1 0.03 0.98 0
168 INT327878 Binding of Egf and Postn 1 0.18 0.37 0
169 INT277664 Negative_regulation of Binding of EGF and EGFR 1 0.18 0.5 0
170 INT170497 Positive_regulation of Egf Positive_regulation of Mapk1 1 0.21 0.08 0
171 INT226726 Egf Positive_regulation of Egfr 1 0.01 0.49 0
172 INT304185 Mapk1 Positive_regulation of Positive_regulation of Egf 1 0.09 0.71 0
173 INT160861 Erbb2 Regulation of EGF 1 0.49 0.73 0
174 INT177945 EGF Regulation of ras 1 0.02 0.84 0
175 INT265605 Egf Positive_regulation of Hgf 1 0.14 0.46 0
176 INT341013 Binding of Erbb3 and Nrg1 1 0.04 0.14 0
177 INT295350 Egf Positive_regulation of Binding of Grb7 1 0.42 0 0
178 INT177915 EGF Positive_regulation of Phosphorylation of AKT1 1 0.03 0.51 0
179 INT295346 Egf Positive_regulation of Phosphorylation of Grb7 1 0.42 0 0
180 INT287269 Binding of ERBB3 and PIK3CG 1 0.11 0.74 0
181 INT208019 Gbp1 Positive_regulation of Gene_expression of Egf 1 0.09 0.56 0
182 INT225263 S100a7a Regulation of Phosphorylation of Egf 1 0.04 0.84 0
183 INT309906 Binding of EGF and SRC 1 0.11 0.64 0
184 INT295403 Egf Positive_regulation of Oprk1 1 0.02 0 0
185 INT341023 PIK3CB Positive_regulation of Nrg1 1 0.03 0.06 0
186 INT327100 Binding of BTC and EGF 1 0.04 0.35 0
187 INT295347 Egf Regulation of Fig4 1 0.11 0 0
188 INT295356 Egf Regulation of Localization of Hua 1 0.17 0 0
189 INT177917 Positive_regulation of EGF Positive_regulation of Phosphorylation of MAPK3 1 0.04 0.4 0
190 INT185272 Binding of Egf and Sox1 1 0.21 0 0
191 INT210494 Binding of EGF and TEP1 1 0.02 0.19 0
192 INT185267 Egf Negative_regulation of Gene_expression of Dlx2 1 0.12 0.15 0
193 INT294087 Negative_regulation of Binding of ERBB2 and ERBB3 1 0.08 0.6 0
194 INT277897 EGF Positive_regulation of CALCRL 1 0.00 0.77 0
195 INT285072 EGF Positive_regulation of ITK 1 0.03 0.77 0
196 INT180851 EGF Positive_regulation of Transcription of MT1L 1 0.27 1.06 0
197 INT327099 Binding of EGF and EREG 1 0.05 0.35 0
198 INT277896 EGF Positive_regulation of TKT 1 0.02 0.76 0
199 INT185266 Egf Regulation of Gene_expression of Dlx2 1 0.12 0.07 0
200 INT341010 Nrg1 Positive_regulation of Regulation of Vim 1 0.07 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of secretion. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of secretion. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT8097 Gene_expression of EGF 122 0.77 75.94 28.47
2 INT11157 Binding of EGF 88 0.48 53.73 21.25
3 INT27739 Positive_regulation of EGF 49 0.70 28.31 13.68
4 INT13823 Gene_expression of Egf 97 0.78 39.99 12.99
5 INT2036 Localization of EGF 42 0.77 21.5 9.74
6 INT24328 Gene_expression of Egf 97 0.75 59.65 9.42
7 INT22771 Positive_regulation of Egf 44 0.70 16.45 8.64
8 INT2037 Negative_regulation of EGF 30 0.59 15.05 6.81
9 INT13822 Localization of Egf 30 0.81 13.79 6.4
10 INT37227 Regulation of EGF 19 0.45 11.16 5.17
11 INT21901 Negative_regulation of Egf 25 0.58 10.46 4.99
12 INT65926 Positive_regulation of Gene_expression of Egf 26 0.70 12.91 4.18
13 INT23653 Binding of Egf 22 0.36 11.34 4.12
14 INT15771 Gene_expression of Nrg1 34 0.67 3.16 4.11
15 INT31758 Positive_regulation of Egf 32 0.66 19.42 3.64
16 INT18920 Binding of Egf 24 0.48 9.43 3.57
17 INT8096 Positive_regulation of Gene_expression of EGF 21 0.69 13.43 3.47
18 INT31757 Negative_regulation of Egf 18 0.41 9.7 2.94
19 INT78253 Gene_expression of Npy2r 7 0.77 1.49 2.89
20 INT117785 Regulation of Gene_expression of EGF 7 0.44 4.22 2.87
21 INT8095 Gene_expression of ERBB3 47 0.77 24.85 2.82
22 INT28878 Negative_regulation of Localization of Egf 6 0.49 10.34 2.57
23 INT77636 Phosphorylation of Egf 11 0.61 1.69 2.56
24 INT57664 Gene_expression of Npy2r 4 0.19 1.41 2.26
25 INT82226 Negative_regulation of Gene_expression of EGF 11 0.58 6.36 2.13
26 INT108335 Phosphorylation of EGF 17 0.80 7.3 2.09
27 INT168983 Negative_regulation of Nrg1 11 0.43 3.4 2.03
28 INT172961 Localization of Egf 26 0.71 16.74 1.81
29 INT73721 Negative_regulation of Gene_expression of Egf 5 0.43 2.28 1.8
30 INT90800 Negative_regulation of Positive_regulation of EGF 5 0.40 2.78 1.77
31 INT19747 Regulation of Egf 14 0.46 4.67 1.68
32 INT105784 Binding of Nrg1 7 0.37 1.29 1.52
33 INT114525 Negative_regulation of Positive_regulation of Egf 4 0.35 2.93 1.5
34 INT86382 Negative_regulation of Localization of EGF 5 0.43 1.75 1.44
35 INT66527 Positive_regulation of Npy2r 2 0.31 0.47 1.44
36 INT158056 Localization of Nrg1 13 0.79 3.11 1.28
37 INT27108 Positive_regulation of Localization of Egf 5 0.50 2.91 1.21
38 INT58311 Regulation of Localization of EGF 3 0.54 1.06 1.16
39 INT162124 Positive_regulation of Phosphorylation of Egf 3 0.45 0.77 1.14
40 INT30851 Gene_expression of NRG1 8 0.67 4.64 1.12
41 INT22770 Regulation of Gene_expression of Egf 5 0.44 2.56 1.12
42 INT37207 Positive_regulation of Positive_regulation of Egf 4 0.50 0.76 1.07
43 INT13817 Protein_catabolism of EGF 3 1.00 1.44 1.06
44 INT101994 Positive_regulation of Nrg1 10 0.50 1.24 1.05
45 INT105860 Positive_regulation of Positive_regulation of EGF 6 0.64 2.37 1.05
46 INT184240 Positive_regulation of Localization of Egf 2 0.27 3.58 0.99
47 INT19084 Negative_regulation of NRG1 5 0.42 4.9 0.96
48 INT66526 Regulation of Positive_regulation of Npy2r 1 0.20 0 0.96
49 INT80315 Binding of Npy2r 2 0.48 0.53 0.95
50 INT118290 Regulation of Phosphorylation of EGF 1 0.32 0.72 0.87
51 INT171372 Positive_regulation of Gene_expression of Egf 16 0.66 9.82 0.84
52 INT80316 Positive_regulation of Npy2r 3 0.31 0.28 0.78
53 INT31759 Negative_regulation of Gene_expression of Egf 6 0.53 5.33 0.77
54 INT159982 Negative_regulation of ERBB3 11 0.26 8.44 0.75
55 INT139846 Protein_catabolism of Nrg1 5 0.60 1.78 0.74
56 INT126736 Positive_regulation of Gene_expression of Nrg1 3 0.50 0.42 0.71
57 INT22772 Positive_regulation of Negative_regulation of Egf 1 0.50 1.48 0.71
58 INT70652 Negative_regulation of Binding of EGF 7 0.43 4.23 0.7
59 INT110854 Phosphorylation of Egf 8 0.75 5.62 0.67
60 INT228279 Regulation of Gene_expression of Egf 7 0.43 6.64 0.65
61 INT128728 Localization of Npy2r 3 0.80 0 0.65
62 INT78255 Transcription of Npy2r 1 0.12 0.59 0.62
63 INT290081 Regulation of NRG1 7 0.26 5.24 0.59
64 INT260422 Positive_regulation of Localization of EGF 3 0.10 1.58 0.56
65 INT80317 Positive_regulation of Binding of Npy2r 1 0.16 0.34 0.56
66 INT115532 Negative_regulation of Positive_regulation of Egf 3 0.28 1.38 0.52
67 INT15770 Negative_regulation of Gene_expression of Nrg1 3 0.43 1.27 0.5
68 INT19083 Positive_regulation of NRG1 3 0.20 0.65 0.48
69 INT290096 Regulation of Gene_expression of NRG1 2 0.06 2.21 0.35
70 INT82763 Regulation of Positive_regulation of Egf 1 0.26 0.68 0.35
71 INT102597 Regulation of Localization of Egf 2 0.62 0.1 0.34
72 INT225248 Positive_regulation of Phosphorylation of Egf 2 0.32 2.02 0.34
73 INT334851 Positive_regulation of Localization of Nrg1 1 0.30 0.68 0.34
74 INT13824 Transcription of Egf 6 0.56 0.94 0.33
75 INT72107 Positive_regulation of Protein_catabolism of Egf 2 0.16 0.34 0.32
76 INT72106 Protein_catabolism of Egf 2 0.31 0.34 0.32
77 INT178301 Regulation of Egf 9 0.58 4.96 0.31
78 INT142132 Positive_regulation of Erbb3 3 0.27 0.82 0.3
79 INT21789 Positive_regulation of ERBB3 7 0.47 4.26 0.29
80 INT13818 Negative_regulation of Protein_catabolism of EGF 1 0.59 0.37 0.27
81 INT203557 Transcription of NRG1 2 0.31 0.7 0.24
82 INT64107 Negative_regulation of Npy2r 1 0.12 0 0.2
83 INT111291 Transcription of EGF 2 0.52 0.35 0.17
84 INT54093 Protein_catabolism of NRG1 1 0.26 0 0.16
85 INT231264 Gene_expression of Erbb3 9 0.35 1.45 0.15
86 INT231261 Regulation of Nrg1 3 0.31 1.32 0.15
87 INT185256 Positive_regulation of Binding of Egf 3 0.32 2.17 0.15
88 INT78262 Transcription of Npy2r 1 0.07 0 0.15
89 INT220571 Positive_regulation of Protein_catabolism of Nrg1 1 0.30 0.08 0.15
90 INT250408 Positive_regulation of Gene_expression of Npy2r 1 0.08 0.09 0.12
91 INT111294 Negative_regulation of Transcription of EGF 1 0.32 0.09 0.12
92 INT203559 Positive_regulation of Transcription of NRG1 1 0.22 0 0.11
93 INT8098 Positive_regulation of Gene_expression of ERBB3 7 0.69 3.79 0.1
94 INT220434 Negative_regulation of Gene_expression of ERBB3 1 0.03 0.4 0.1
95 INT184509 Regulation of Negative_regulation of ERBB3 1 0.01 0.47 0.1
96 INT54092 Regulation of Protein_catabolism of NRG1 1 0.13 0 0.09
97 INT70651 Positive_regulation of Binding of EGF 1 0.50 0.98 0.09
98 INT8099 Binding of ERBB3 7 0.36 3.09 0.08
99 INT329735 Negative_regulation of Protein_catabolism of Nrg1 1 0.36 0.49 0.08
100 INT54094 Positive_regulation of Protein_catabolism of NRG1 1 0.14 0 0.07
101 INT185035 Regulation of ERBB3 3 0.42 6.5 0.06
102 INT283831 Regulation of Regulation of Egf 2 0.29 1.5 0.06
103 INT334840 Positive_regulation of Phosphorylation of Nrg1 1 0.30 0 0.06
104 INT290102 Localization of NRG1 1 0.15 0.76 0.06
105 INT220593 Negative_regulation of Localization of Nrg1 1 0.26 0.07 0.04
106 INT334841 Negative_regulation of Phosphorylation of Nrg1 1 0.26 0 0.03
107 INT340964 Positive_regulation of Negative_regulation of Nrg1 1 0.28 0.12 0.03
108 INT334845 Phosphorylation of Nrg1 1 0.49 0 0.03
109 INT266932 Transcription of ERBB3 4 0.43 1.7 0
110 INT118289 Negative_regulation of Phosphorylation of EGF 3 0.40 0.47 0
111 INT279809 Localization of ERBB3 3 0.01 2.08 0
112 INT282444 Regulation of Gene_expression of Erbb3 1 0.11 0.84 0
113 INT304183 Positive_regulation of Positive_regulation of Egf 1 0.27 1.52 0
114 INT340965 Negative_regulation of Binding of Nrg1 1 0.24 0 0
115 INT220588 Transcription of Nrg1 1 0.41 0.64 0
116 INT282449 Regulation of Positive_regulation of Erbb3 1 0.11 0.91 0
117 INT171658 Binding of NRG1 1 0.05 0.17 0
118 INT76871 Regulation of Npy2r 1 0.19 0 0
119 INT340961 Positive_regulation of Gene_expression of Erbb3 1 0.09 0 0
120 INT340957 Binding of Erbb3 1 0.07 0.13 0
121 INT286986 Phosphorylation of ERBB3 1 0.28 0.83 0
122 INT340950 Negative_regulation of Erbb3 1 0.08 0 0
123 INT340972 Negative_regulation of Gene_expression of Erbb3 1 0.08 0 0
124 INT340944 Positive_regulation of Phosphorylation of Erbb3 1 0.09 0.13 0
125 INT340958 Negative_regulation of Binding of Erbb3 1 0.08 0 0
126 INT313602 Negative_regulation of Binding of ERBB3 1 0.18 0.58 0
127 INT340954 Positive_regulation of Positive_regulation of Nrg1 1 0.28 0 0
128 INT234187 Positive_regulation of Gene_expression of NRG1 1 0.02 0.32 0
129 INT172967 Negative_regulation of Phosphorylation of Egf 1 0.17 0.95 0
130 INT71715 Positive_regulation of Negative_regulation of Egf 1 0.06 0.07 0
131 INT340945 Phosphorylation of Erbb3 1 0.12 0.13 0
132 INT340974 Negative_regulation of Negative_regulation of Nrg1 1 0.24 0 0
133 INT295399 Negative_regulation of Transcription of Egf 1 0.35 0 0
134 INT340968 Positive_regulation of Binding of Erbb3 1 0.09 0.13 0
135 INT231271 Regulation of Localization of Nrg1 1 0.45 0 0
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