GO:0051087

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Name chaperone binding
Categary Function
Go Slim No
Go Link GO:0051087
Unique Molecular Interactions 1239
Total Molecular Interactions 1632
Total Single Events 19116
Pain Genes Associated 57

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for chaperone binding. They are ordered first by their pain relevance and then by number of times they were reported for chaperone binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT206768 TP53 Positive_regulation of Ltp 2 0.01 5.83 10.21
2 INT30423 Penk Regulation of Localization of Ins1 4 0.26 0.77 4.42
3 INT95730 Binding of CP and SPINK1 2 0.19 5.65 4.02
4 INT202959 Binding of BAG3 and MCRS1 1 0.11 7.46 3.14
5 INT202965 Binding of STC2 and BAG3 1 0.02 7.86 2.96
6 INT202974 Binding of BAG3 and CPP 1 0.25 6.22 2.73
7 INT67663 Ins1 Positive_regulation of Ntrk2 1 0.00 0.19 2.59
8 INT130284 Ins1 Negative_regulation of Gene_expression of Npy 1 0.32 0.1 2.47
9 INT312690 CP Positive_regulation of CCL20 1 0.11 8.23 2.2
10 INT66157 Binding of ALB and BDP1 1 0.11 0 2.13
11 INT275851 PES1 Negative_regulation of CP 1 0.01 1.96 1.83
12 INT19496 Pomc Regulation of Localization of Ins1 1 0.55 0.33 1.82
13 INT18520 Adra2c Positive_regulation of Localization of Ins1 3 0.41 0.63 1.66
14 INT326509 Binding of ACE and VWF 1 0.05 2.07 1.59
15 INT26985 Cpe Negative_regulation of Localization of Ins1 1 0.02 0 1.57
16 INT158762 Binding of Vwf and Mthfr 1 0.05 1.85 1.37
17 INT39950 Binding of ALB and PDYN 1 0.31 0 1.32
18 INT42579 SOD1 Negative_regulation of POMC 1 0.16 0.43 1.27
19 INT19819 Penk Regulation of Gene_expression of Ins1 1 0.05 0 1.27
20 INT142431 Cp Positive_regulation of Crh 1 0.31 1.49 1.26
21 INT116628 St13 Regulation of Positive_regulation of P9Ehs1 1 0.00 0 1.25
22 INT18324 Sst Negative_regulation of Localization of Ins1 2 0.46 1.09 1.24
23 INT147446 ADCYAP1 Regulation of Localization of CP 1 0.02 1.12 1.16
24 INT19535 Binding of ADRA1D and ALB 3 0.42 0.8 1.15
25 INT121362 Trpv1 Regulation of Localization of Ins1 1 0.51 0.17 1.12
26 INT161011 Binding of Cpe and St13 2 0.03 0.61 1.07
27 INT175553 Binding of CASR and CP 1 0.11 1.65 1.03
28 INT19494 Pomc Positive_regulation of Localization of Ins1 2 0.62 0.38 1.02
29 INT12138 Ins1 Negative_regulation of Chat 1 0.27 0.71 1.01
30 INT54853 Negative_regulation of Adra1a Positive_regulation of Positive_regulation of Ins1 1 0.18 0.23 1
31 INT54852 Negative_regulation of Adra1a Positive_regulation of Ins1 1 0.18 0.23 0.99
32 INT73681 Regulation of KNG1 Positive_regulation of ALB 1 0.30 0.38 0.99
33 INT130232 Binding of Cat and Sod1 1 0.35 0.3 0.98
34 INT73680 KNG1 Positive_regulation of ALB 1 0.51 0.38 0.98
35 INT130231 Positive_regulation of Binding of Cat and Sod1 1 0.46 0.3 0.98
36 INT37308 Ins1 Regulation of Localization of Gast 1 0.20 0 0.97
37 INT73461 PTPLA Positive_regulation of Transcription of TP53 1 0.06 0.99 0.96
38 INT330629 TP53 Negative_regulation of Gene_expression of Fos 1 0.30 1.76 0.94
39 INT256897 IGKV1D-39 Regulation of BAG3 1 0.04 1.77 0.94
40 INT115656 Glp1r Positive_regulation of Localization of Ins1 2 0.42 5.23 0.91
41 INT54854 Sorbs1 Regulation of Ins1 1 0.34 0.23 0.9
42 INT12766 Ins1 Positive_regulation of Prkcg 3 0.53 0.07 0.89
43 INT26991 Pomc Negative_regulation of Localization of Ins1 1 0.38 0 0.89
44 INT18325 Grem2 Positive_regulation of Ins1 1 0.02 0.9 0.88
45 INT26987 Pomc Regulation of Ins1 1 0.40 0 0.87
46 INT26984 Cpe Regulation of Ins1 1 0.02 0 0.87
47 INT343847 IRF6 Positive_regulation of TBCE 1 0.01 1.11 0.87
48 INT330630 Binding of TP53 and Car1 1 0.23 1.56 0.86
49 INT114546 Ins1 Positive_regulation of Positive_regulation of Trpv1 1 0.39 0.19 0.86
50 INT30422 Penk Regulation of Ins1 1 0.06 0 0.85
51 INT222985 CP Positive_regulation of Positive_regulation of TGFB1 1 0.00 1.57 0.85
52 INT343829 TLR1 Positive_regulation of TBCE 1 0.03 0.96 0.85
53 INT115655 Glp1r Positive_regulation of Ins1 1 0.42 0 0.84
54 INT151409 Binding of Cp and Cd8b 1 0.16 0 0.84
55 INT12142 Ins1 Regulation of Chat 1 0.24 0.69 0.84
56 INT97057 Bcl2l1 Regulation of Gene_expression of Trp53 1 0.36 0.51 0.83
57 INT97058 Cpz Regulation of Gene_expression of Trp53 1 0.27 0.57 0.83
58 INT309001 Ins1 Positive_regulation of Mmp9 1 0.20 1.96 0.83
59 INT120149 Positive_regulation of Pomc Positive_regulation of Localization of Ins1 1 0.03 0.09 0.82
60 INT41108 Adarb1 Positive_regulation of Localization of Ins1 1 0.03 0 0.81
61 INT218037 Binding of ALB and Penk 1 0.13 0 0.81
62 INT110726 Binding of ALB and LTF 1 0.01 0 0.81
63 INT34241 Dlst Positive_regulation of Positive_regulation of LH 1 0.28 0 0.77
64 INT114547 Ins1 Positive_regulation of Trpv1 1 0.36 0.19 0.77
65 INT164996 Ins1 Regulation of Gria2 1 0.05 0.05 0.76
66 INT250959 Binding of HLA-B and SOD1 1 0.05 0.75 0.75
67 INT139893 Binding of Alb and Alms1 1 0.04 0.48 0.75
68 INT26983 Cpe Regulation of Localization of Ins1 1 0.02 0 0.75
69 INT19818 Penk Positive_regulation of Gene_expression of Ins1 1 0.32 0 0.74
70 INT316673 Binding of CALR and LRP1 1 0.39 1.89 0.74
71 INT45822 Pah Positive_regulation of Localization of Ins1 1 0.01 0.3 0.73
72 INT101442 Penk Positive_regulation of Localization of Ins1 1 0.29 0.9 0.73
73 INT296097 Acsm3 Negative_regulation of SOD1 1 0.01 1.3 0.72
74 INT64117 Binding of Edn1 and Ins1 1 0.06 0.85 0.71
75 INT81735 Binding of Ins1 and Pomc 1 0.20 2.24 0.71
76 INT31417 Cocia8 Positive_regulation of Ins1 1 0.01 0 0.7
77 INT31415 Regulation of Cocia8 Positive_regulation of Ins1 1 0.00 0 0.7
78 INT27690 Ins1 Negative_regulation of GYPA 1 0.00 0.73 0.69
79 INT94241 Binding of Cp and Slc2a2 1 0.13 0.81 0.67
80 INT101986 TP53 Positive_regulation of Gene_expression of GDF15 1 0.52 2.45 0.67
81 INT28975 Ins1 Positive_regulation of Positive_regulation of Dbh 1 0.21 0 0.66
82 INT312694 PCA Regulation of Localization of CP 1 0.05 2.65 0.66
83 INT296793 Akt1 Positive_regulation of Gene_expression of Bax 1 0.11 0.75 0.65
84 INT78663 Dlst Regulation of Nos1 1 0.19 0.91 0.65
85 INT296790 Tlr9 Regulation of Bax 1 0.14 0.76 0.65
86 INT296791 Positive_regulation of Akt1 Positive_regulation of Gene_expression of Bax 1 0.11 0.8 0.65
87 INT137099 Dlst Regulation of Sec22b 1 0.05 0 0.64
88 INT267888 St13 Positive_regulation of Insrr 1 0.00 0.07 0.64
89 INT92045 Binding of ALB and SERPINA1 1 0.30 1.37 0.64
90 INT137100 Dlst Regulation of Htr1a 1 0.18 0 0.64
91 INT318981 Binding of CALR and GOPC 1 0.03 0.77 0.64
92 INT253137 Ptpn1 Negative_regulation of Ins1 1 0.19 4.11 0.63
93 INT142432 Regulation of Cp Positive_regulation of Crh 1 0.18 0.75 0.63
94 INT142430 Cp Positive_regulation of Gal 1 0.30 0.74 0.62
95 INT202962 CPP Negative_regulation of Positive_regulation of BAG3 1 0.26 1.34 0.61
96 INT166402 CDKN1A Regulation of Gene_expression of TP53 1 0.27 0.83 0.61
97 INT112699 Bid Regulation of Bax 1 0.25 0.51 0.61
98 INT139901 Ins1 Positive_regulation of Akt1 9 0.31 4.58 0.6
99 INT317638 Ins1 Positive_regulation of Gene_expression of Drd1a 1 0.14 0.86 0.59
100 INT317634 Ins1 Positive_regulation of Drd1a 1 0.14 0.86 0.59
101 INT321300 Ins1 Negative_regulation of Pck1 1 0.09 0.52 0.59
102 INT202971 Binding of BAG3 and CAP1 1 0.04 1.26 0.59
103 INT321285 Ins1 Negative_regulation of G6pc 1 0.07 0.52 0.59
104 INT94240 Binding of Cp and Ins1 1 0.02 0.7 0.58
105 INT267887 St13 Positive_regulation of Localization of Insrr 1 0.00 0 0.58
106 INT34239 Dlst Regulation of Positive_regulation of LH 1 0.27 0 0.57
107 INT50883 Binding of AGTR2 and ALB 1 0.37 0.19 0.56
108 INT27871 Binding of FCGR1B and HSPD1 1 0.01 1.93 0.56
109 INT27872 Positive_regulation of Binding of FCGR1B and HSPD1 1 0.01 1.93 0.56
110 INT544 Binding of ALB and GC 1 0.13 0 0.55
111 INT34242 Dlst Regulation of Localization of LH 1 0.43 0 0.55
112 INT114029 Binding of ALB and Mmp3 1 0.01 0.31 0.55
113 INT351581 Binding of ALB and GOPC 1 0.11 0 0.55
114 INT114028 Negative_regulation of Binding of ALB and Mmp3 1 0.01 0.31 0.55
115 INT77508 ST13 Negative_regulation of Gene_expression of CD9 1 0.09 0.5 0.54
116 INT267889 St13 Regulation of Insrr 1 0.00 0.43 0.54
117 INT240808 Arc Regulation of Ins1 1 0.09 1.41 0.54
118 INT80833 Oxt Regulation of Ins1 1 0.04 0 0.53
119 INT10079 Cp Regulation of Trh 1 0.01 0.59 0.53
120 INT80835 Oxt Positive_regulation of Regulation of Ins1 1 0.04 0 0.53
121 INT254200 Mif Regulation of Trp53 1 0.02 0.96 0.52
122 INT3218 Adrb2 Positive_regulation of Localization of Ins1 1 0.10 0 0.52
123 INT30028 Ins1 Regulation of Odc1 2 0.11 0 0.51
124 INT343859 Binding of IRF6 and TBCE 1 0.01 1.1 0.51
125 INT343860 Binding of CD14 and TBCE 1 0.03 1.1 0.51
126 INT27730 Binding of ALB and Shbg 2 0.01 0.44 0.5
127 INT352521 Cnn1 Positive_regulation of Cp 1 0.00 1.45 0.5
128 INT274625 OPN1MW Positive_regulation of SOD1 1 0.19 0.29 0.5
129 INT324816 Hspd1 Positive_regulation of Gene_expression of Ik 1 0.00 1.59 0.5
130 INT31712 Ptger2 Positive_regulation of Localization of Ins1 1 0.13 0.06 0.49
131 INT229128 Binding of CP and PRSS1 1 0.14 0.77 0.47
132 INT41174 Bak1 Regulation of Localization of Prl 1 0.02 0 0.46
133 INT340291 Ea1 Regulation of Gene_expression of Ins1 1 0.03 0.62 0.46
134 INT17774 Alb Negative_regulation of Dnase1 1 0.02 0 0.46
135 INT238638 Gopc Negative_regulation of Gene_expression of Bax 1 0.04 0.85 0.45
136 INT258636 Binding of Alb and Is(HSR;1)1Icg 1 0.05 0 0.44
137 INT241914 SOD1 Positive_regulation of Ros1 1 0.00 0.76 0.44
138 INT148378 CP Positive_regulation of NOTCH1 1 0.11 0.64 0.44
139 INT148380 PDP1 Positive_regulation of Positive_regulation of CP 1 0.12 0.64 0.44
140 INT348784 Ins1 Positive_regulation of Irs1 1 0.09 3.47 0.44
141 INT340292 Ea1 Positive_regulation of Ins1 1 0.04 0.6 0.43
142 INT323484 Ghsr Positive_regulation of Localization of Ins1 1 0.27 0.87 0.43
143 INT302829 Mapkapk5 Positive_regulation of Trp53 1 0.07 0.81 0.43
144 INT51167 Defb35 Regulation of Localization of Ins1 1 0.02 0.08 0.42
145 INT12139 Ins1 Regulation of Gad1 1 0.15 0.33 0.42
146 INT348785 Ins1 Positive_regulation of Phosphorylation of Akt1 1 0.17 3.5 0.42
147 INT231303 Binding of Prnp and Helt 1 0.02 3.23 0.41
148 INT231304 Prnp Negative_regulation of Grin2d 2 0.38 0.5 0.4
149 INT276216 Binding of Akt1 and Ins1 2 0.03 2.61 0.4
150 INT120894 Binding of Gp1ba and Vwf 1 0.00 1.38 0.4
151 INT100598 PRNP Positive_regulation of Gene_expression of IL6 1 0.40 0.23 0.4
152 INT64640 Ins1 Regulation of LH 1 0.13 0.38 0.4
153 INT46225 Binding of ALB and POMC 1 0.36 0 0.4
154 INT323491 Olfr781 Positive_regulation of Localization of Ins1 1 0.01 0.87 0.4
155 INT153422 Ins1 Regulation of Transcription of Qrfp 1 0.08 0.23 0.4
156 INT288700 Binding of Cp and Tfrc 1 0.40 0 0.39
157 INT64642 Ins1 Positive_regulation of Localization of Gnrh1 1 0.06 0.44 0.39
158 INT12767 Ins1 Positive_regulation of Phosphorylation of Prkcg 1 0.36 0 0.38
159 INT40395 Ins1 Positive_regulation of Localization of Avp 1 0.16 0.09 0.38
160 INT64641 Ins1 Positive_regulation of Gnrh1 1 0.06 0.44 0.38
161 INT43956 GCG Regulation of ALB 1 0.16 0.15 0.38
162 INT250956 Positive_regulation of Binding of HLA-B and SOD1 1 0.07 0.38 0.38
163 INT146611 Ins1 Positive_regulation of Phosphorylation of Akt1 9 0.23 4.34 0.37
164 INT161005 Binding of Gfap and St13 1 0.15 0.52 0.37
165 INT161010 Gfap Regulation of St13 1 0.05 0.52 0.37
166 INT151698 Binding of RNF130 and Vwf 1 0.04 0.29 0.37
167 INT316675 Binding of CALR and SFTPD 1 0.35 0.96 0.37
168 INT67031 Ins1 Regulation of Etf1 1 0.01 0.69 0.37
169 INT161002 Binding of Itgam and St13 1 0.11 0.52 0.37
170 INT161008 Itgam Regulation of St13 1 0.08 0.52 0.37
171 INT134427 Alb Regulation of GGT1 1 0.05 0.7 0.35
172 INT31713 Adra2c Regulation of Localization of Ins1 1 0.22 0.31 0.35
173 INT309003 Ins1 Positive_regulation of TNF 1 0.05 1.74 0.35
174 INT253944 Positive_regulation of Prkca Positive_regulation of Gene_expression of Ins1 1 0.01 1.53 0.35
175 INT155061 Stat3 Negative_regulation of Bax 1 0.22 3.71 0.34
176 INT24530 Gal Negative_regulation of Localization of Ins1 1 0.16 0.18 0.34
177 INT67000 Dnajc3 Negative_regulation of Negative_regulation of Penk 1 0.00 0.54 0.34
178 INT173478 Th Regulation of Localization of Ins1 1 0.13 0 0.34
179 INT323352 Binding of F8 and VWF 5 0.08 2.22 0.33
180 INT333993 Binding of Vcam1 and Vwf 1 0.00 1.32 0.33
181 INT37311 Ins1 Regulation of Gast 1 0.05 0 0.33
182 INT323502 Ghrl Positive_regulation of Localization of Ins1 1 0.15 1.58 0.33
183 INT39594 TPO Positive_regulation of CALR 1 0.30 0.91 0.32
184 INT91814 Binding of TNF and TP53 1 0.14 2.2 0.32
185 INT282420 Spp1 Positive_regulation of Ins1 1 0.20 1.25 0.32
186 INT166394 CDKN1B Regulation of Gene_expression of TP53 1 0.28 0.41 0.31
187 INT105873 Ins1 Negative_regulation of Positive_regulation of Lep 1 0.27 0.67 0.31
188 INT231306 Prnp Regulation of Grin1 1 0.60 0.35 0.31
189 INT318323 Binding of GRB2 and HSPA5 1 0.34 0.28 0.31
190 INT227339 Binding of TNF and Ins1 1 0.28 4.08 0.31
191 INT282421 Mapk8 Negative_regulation of Ins1 1 0.06 2.48 0.31
192 INT166396 IFI27 Regulation of Gene_expression of TP53 1 0.19 0.41 0.31
193 INT220521 Ugt1a6b Positive_regulation of Cdkn1b 1 0.01 2.38 0.31
194 INT178910 Ins1 Negative_regulation of Gene_expression of Pck1 1 0.04 0.34 0.31
195 INT105874 Lep Negative_regulation of Positive_regulation of Ins1 1 0.27 0.67 0.31
196 INT17929 Vip Regulation of Localization of Ins1 1 0.07 0 0.3
197 INT35963 Binding of ALB and MPG 1 0.40 0 0.3
198 INT26737 Alox5 Regulation of Localization of Ins1 1 0.06 0.09 0.3
199 INT118300 Vwf Positive_regulation of Crp 1 0.00 0.87 0.3
200 INT324830 Hspd1 Positive_regulation of IFNA1 1 0.04 0.46 0.3

Single Events

The table below shows the top 100 pain related interactions that have been reported for chaperone binding. They are ordered first by their pain relevance and then by number of times they were reported in chaperone binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT1114 Localization of Ins1 748 0.80 192.95 165.48
2 INT1472 Positive_regulation of Ins1 349 0.69 146.2 86.36
3 INT3214 Localization of Ins1 527 0.80 196.9 79.26
4 INT3657 Gene_expression of Ins1 514 0.78 321.69 75.76
5 INT1988 Positive_regulation of Localization of Ins1 254 0.69 59.25 68.37
6 INT546 Binding of ALB 311 0.48 85.98 60.14
7 INT1200 Negative_regulation of Ins1 274 0.58 155.17 56.14
8 INT2276 Regulation of Ins1 234 0.61 103.78 54.05
9 INT3213 Gene_expression of Ins1 511 0.76 357.59 53.32
10 INT2275 Negative_regulation of Localization of Ins1 183 0.59 51.02 44.94
11 INT1474 Regulation of Localization of Ins1 132 0.61 25.96 43.07
12 INT613 Gene_expression of Alb 268 0.78 149.84 42.78
13 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75
14 INT3971 Positive_regulation of Alb 175 0.70 98.46 36.45
15 INT3216 Positive_regulation of Localization of Ins1 170 0.69 56.78 35.63
16 INT8747 Positive_regulation of Ins1 221 0.69 154.28 35.15
17 INT234 Binding of Alb 151 0.48 52.34 32.97
18 INT724 Negative_regulation of Alb 151 0.59 93.57 29.65
19 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8
20 INT3217 Regulation of Ins1 154 0.62 87.11 27.29
21 INT3760 Positive_regulation of ALB 142 0.70 87.46 26.7
22 INT100423 Gene_expression of Bax 141 0.75 98.43 24.48
23 INT18323 Negative_regulation of Localization of Ins1 122 0.58 45.74 23.04
24 INT18322 Negative_regulation of Ins1 132 0.58 88.49 22.59
25 INT102112 Gene_expression of Prnp 440 0.78 209.32 22.5
26 INT7678 Localization of Alb 142 0.81 80.93 22.49
27 INT3952 Negative_regulation of ALB 116 0.59 72.18 18.35
28 INT9900 Positive_regulation of Vwf 80 0.69 51.85 18.13
29 INT3656 Positive_regulation of Gene_expression of Ins1 74 0.54 44.94 17.36
30 INT65856 Positive_regulation of TP53 138 0.67 112.65 16.71
31 INT2432 Positive_regulation of Cp 41 0.67 31.1 16.68
32 INT93361 Gene_expression of Trp53 208 0.78 175.35 16.65
33 INT8742 Regulation of Localization of Ins1 65 0.61 14.98 16.43
34 INT6110 Negative_regulation of Gene_expression of Ins1 83 0.56 60.59 16.07
35 INT80972 Gene_expression of Tp53 104 0.78 102.74 16.02
36 INT2383 Positive_regulation of CP 33 0.67 25.41 15.38
37 INT615 Regulation of Alb 66 0.62 33.43 15.33
38 INT116465 Gene_expression of Birc5 241 0.78 192.31 15.32
39 INT109511 Gene_expression of Bax 133 0.78 113.22 14.36
40 INT18773 Localization of ALB 117 0.80 69.18 13.8
41 INT69569 Positive_regulation of Prnp 175 0.70 96.31 13.34
42 INT2578 Binding of Ins1 74 0.48 33.57 12.92
43 INT31990 Positive_regulation of SOD1 124 0.69 67.79 12.52
44 INT14510 Gene_expression of SOD1 208 0.76 88.56 12.4
45 INT39587 Gene_expression of CP 42 0.65 31.48 11.87
46 INT105754 Regulation of St13 8 0.28 0.75 11.41
47 INT27687 Regulation of Cp 20 0.53 9.75 10.8
48 INT111335 Gene_expression of HSPD1 57 0.75 55.51 10.38
49 INT169997 Positive_regulation of Gene_expression of Tp53 37 0.70 47.3 9.85
50 INT102110 Positive_regulation of Gene_expression of Bax 42 0.67 35.77 9.51
51 INT129585 Gene_expression of St13 17 0.59 4.46 9.3
52 INT102106 Positive_regulation of Bax 48 0.67 30.62 9.28
53 INT46273 Gene_expression of PRNP 103 0.78 110.34 9.25
54 INT9899 Gene_expression of Vwf 91 0.74 45.06 9.13
55 INT80037 Gene_expression of BAK1 58 0.75 39.49 9.08
56 INT860 Regulation of ALB 48 0.60 25.11 8.95
57 INT15805 Gene_expression of TFRC 35 0.75 17.44 8.52
58 INT2512 Negative_regulation of Cp 27 0.51 10.15 8.37
59 INT12762 Negative_regulation of Positive_regulation of Ins1 24 0.59 8.51 8.28
60 INT18583 Positive_regulation of Gene_expression of Ins1 67 0.50 49.72 8.26
61 INT60034 Positive_regulation of VWF 40 0.68 30.42 8.15
62 INT67037 Gene_expression of Sod1 121 0.78 59.32 7.99
63 INT53487 Gene_expression of TSC1 81 0.58 77.71 7.94
64 INT12010 Gene_expression of Cp 38 0.65 20.55 7.84
65 INT57748 Positive_regulation of Gene_expression of TP53 85 0.69 79.55 7.49
66 INT102107 Negative_regulation of Gene_expression of Bax 30 0.57 29.48 7.33
67 INT97055 Positive_regulation of Gene_expression of Trp53 51 0.70 45.7 7.25
68 INT162253 Gene_expression of BAG3 30 0.59 20.16 7.18
69 INT55957 Positive_regulation of PRNP 57 0.67 37.87 7.11
70 INT47540 Binding of Cp 20 0.41 15.54 7.01
71 INT14903 Negative_regulation of SOD1 81 0.57 42.02 6.91
72 INT3757 Positive_regulation of Gene_expression of ALB 45 0.69 23.73 6.85
73 INT11150 Positive_regulation of Dlst 31 0.51 9.01 6.63
74 INT3309 Binding of CP 25 0.47 17.87 6.62
75 INT39516 Gene_expression of Alb 81 0.75 30.08 6.59
76 INT98837 Positive_regulation of Bax 72 0.61 63.14 6.41
77 INT2217 Positive_regulation of Positive_regulation of Ins1 21 0.69 7.66 6.32
78 INT11814 Positive_regulation of Alb 43 0.63 31.71 6.28
79 INT93359 Positive_regulation of Trp53 90 0.70 69.77 6.24
80 INT4422 Positive_regulation of Gene_expression of Alb 30 0.50 18.56 6.12
81 INT91217 Positive_regulation of BAG3 22 0.48 16.57 6.06
82 INT117621 Positive_regulation of HSPA5 17 0.59 13.26 6.06
83 INT27591 Negative_regulation of Gene_expression of Alb 30 0.58 17.03 5.99
84 INT112545 Phosphorylation of TP53 28 0.80 14.13 5.93
85 INT17425 Regulation of Gene_expression of Ins1 23 0.45 18.99 5.61
86 INT32458 Gene_expression of VWF 57 0.78 28.97 5.56
87 INT28088 Binding of Alb 34 0.47 11.06 5.48
88 INT69572 Localization of Prnp 96 0.81 38.11 5.45
89 INT91754 Gene_expression of Cp 42 0.77 21.97 5.38
90 INT74250 Negative_regulation of Gene_expression of Ins1 47 0.40 39.27 5.37
91 INT145929 Regulation of Bax 20 0.60 18.12 5.35
92 INT60585 Regulation of TP53 59 0.59 54.55 5.21
93 INT10888 Binding of Vwf 32 0.46 22.87 5.21
94 INT2579 Protein_catabolism of Ins1 43 0.99 9.91 5.14
95 INT109513 Positive_regulation of Gene_expression of Bax 37 0.67 29.52 5.06
96 INT30738 Negative_regulation of Gene_expression of ALB 32 0.59 19.01 5.04
97 INT116464 Negative_regulation of Birc5 53 0.59 45.4 4.91
98 INT28176 Localization of Cp 17 0.73 14.3 4.86
99 INT3215 Regulation of Gene_expression of Ins1 32 0.52 19.83 4.85
100 INT102254 Positive_regulation of Gene_expression of Prnp 72 0.70 38.11 4.81
101 INT162254 Regulation of BAG3 28 0.41 18.12 4.75
102 INT137332 Positive_regulation of Gene_expression of Sod1 41 0.70 19.8 4.69
103 INT109972 Phosphorylation of Trp53 13 0.80 6.15 4.68
104 INT74447 Gene_expression of Vwf 39 0.76 21.96 4.66
105 INT62684 Negative_regulation of TP53 66 0.58 66.09 4.62
106 INT76884 Positive_regulation of Cp 22 0.69 12.84 4.6
107 INT230810 Phosphorylation of Ins1 59 0.69 41.15 4.51
108 INT57749 Negative_regulation of Gene_expression of TP53 39 0.56 36.79 4.45
109 INT99504 Negative_regulation of Bax 19 0.56 8.89 4.44
110 INT69570 Binding of Prnp 75 0.48 44.26 4.37
111 INT57642 Gene_expression of PCSK1 26 0.76 5.09 4.28
112 INT168479 Binding of BAG3 13 0.36 10.68 4.21
113 INT103345 Positive_regulation of Gene_expression of BAK1 10 0.57 6.4 4.19
114 INT19847 Positive_regulation of Localization of Alb 21 0.70 13.89 4.16
115 INT20230 Negative_regulation of Positive_regulation of Alb 15 0.56 12.44 4.11
116 INT182311 Positive_regulation of Birc5 26 0.67 25.32 4.08
117 INT123752 Regulation of Bax 19 0.60 16.45 4
118 INT112692 Localization of Bax 31 0.80 20.97 3.98
119 INT95877 Gene_expression of St13 24 0.49 11.18 3.95
120 INT5408 Localization of Alb 30 0.73 12.1 3.84
121 INT75661 Regulation of CP 12 0.39 5.17 3.75
122 INT129746 Positive_regulation of Gene_expression of Tfrc 4 0.18 2.15 3.74
123 INT73981 Gene_expression of Hspd1 18 0.75 5.69 3.72
124 INT160994 Negative_regulation of St13 9 0.20 4.83 3.71
125 INT10146 Negative_regulation of Vwf 27 0.40 17.11 3.69
126 INT71602 Negative_regulation of Trp53 84 0.59 67.77 3.68
127 INT18192 Regulation of Gene_expression of Alb 16 0.44 9.38 3.57
128 INT73463 Positive_regulation of Gene_expression of TSC1 20 0.38 14.59 3.53
129 INT130351 Positive_regulation of Vwf 18 0.59 5.99 3.48
130 INT10594 Gene_expression of Dlst 33 0.57 6 3.38
131 INT15801 Positive_regulation of TFRC 11 0.33 6.35 3.3
132 INT102255 Regulation of Prnp 35 0.62 18.97 3.25
133 INT68846 Gene_expression of Tfrc 22 0.32 10.1 3.06
134 INT55409 Localization of VWF 17 0.80 8.99 3.06
135 INT143763 Binding of St13 2 0.36 0.72 3.01
136 INT21606 Positive_regulation of Regulation of Ins1 8 0.41 3.9 2.97
137 INT8103 Binding of TP53 46 0.44 40.2 2.96
138 INT15557 Regulation of Localization of Alb 13 0.50 5.71 2.91
139 INT10893 Binding of VWF 27 0.47 25.02 2.82
140 INT31412 Negative_regulation of Positive_regulation of Ins1 10 0.40 7.14 2.82
141 INT130700 Gene_expression of HSPA5 16 0.75 11.55 2.81
142 INT10516 Localization of Vwf 30 0.79 7.54 2.77
143 INT116463 Negative_regulation of Gene_expression of Birc5 40 0.59 33.99 2.74
144 INT74293 Positive_regulation of BAK1 13 0.60 14.13 2.73
145 INT4329 Regulation of Regulation of Ins1 10 0.61 3.17 2.72
146 INT39469 Negative_regulation of Alb 21 0.41 13.33 2.68
147 INT130702 Positive_regulation of Gene_expression of HSPA5 7 0.59 7.53 2.68
148 INT109969 Positive_regulation of Phosphorylation of Trp53 1 0.45 2.18 2.66
149 INT91899 Binding of Sod1 17 0.47 11.56 2.63
150 INT10267 Regulation of Positive_regulation of Ins1 11 0.24 2.74 2.63
151 INT102253 Negative_regulation of Prnp 75 0.59 24.23 2.62
152 INT51753 Negative_regulation of Tfrc 7 0.41 3.47 2.62
153 INT129589 Positive_regulation of St13 6 0.38 3 2.61
154 INT123970 Negative_regulation of BAG3 11 0.38 5.29 2.6
155 INT31989 Binding of SOD1 43 0.47 19.38 2.55
156 INT109968 Positive_regulation of Positive_regulation of Trp53 6 0.47 3.57 2.51
157 INT94010 Positive_regulation of Localization of VWF 9 0.70 4.23 2.5
158 INT205187 Localization of TBCE 3 0.14 4.11 2.47
159 INT135040 Regulation of Gene_expression of Prnp 30 0.62 10.52 2.45
160 INT54555 Negative_regulation of CALR 10 0.41 4.41 2.4
161 INT31134 Regulation of Binding of ALB 13 0.62 2.51 2.37
162 INT55952 Transcription of TP53 16 0.61 12.14 2.36
163 INT21726 Gene_expression of Tfrc 10 0.74 7.38 2.36
164 INT68087 Regulation of Vwf 9 0.39 8.06 2.36
165 INT139896 Phosphorylation of Ins1 29 0.77 24.03 2.35
166 INT102146 Phosphorylation of Bax 4 0.66 3.48 2.35
167 INT182312 Positive_regulation of Gene_expression of Birc5 26 0.69 25.3 2.32
168 INT130230 Positive_regulation of Sod1 3 0.67 1.63 2.3
169 INT182318 Regulation of Birc5 25 0.60 23.58 2.29
170 INT19537 Negative_regulation of Binding of ALB 6 0.43 3.32 2.26
171 INT142626 Negative_regulation of Localization of ALB 9 0.55 6.63 2.24
172 INT46100 Negative_regulation of TBCE 7 0.50 1.96 2.24
173 INT27880 Positive_regulation of HSPD1 17 0.65 18.16 2.23
174 INT111038 Gene_expression of Cdkn1b 23 0.75 25.35 2.22
175 INT121543 Positive_regulation of Gene_expression of PCSK1 4 0.29 1.63 2.21
176 INT152436 Positive_regulation of Gene_expression of HSPD1 12 0.67 10.06 2.16
177 INT28739 Binding of Ins1 35 0.37 22.43 2.14
178 INT154970 Localization of Bax 15 0.74 11.12 2.11
179 INT58108 Positive_regulation of Positive_regulation of ALB 4 0.70 1.02 2.11
180 INT2581 Regulation of Binding of Ins1 7 0.61 2.05 2.08
181 INT36616 Positive_regulation of Binding of ALB 8 0.67 3 2.07
182 INT53668 Regulation of Pcsk1 6 0.53 2.52 2.07
183 INT82543 Negative_regulation of Gene_expression of TFRC 4 0.57 1.27 2.03
184 INT96764 Positive_regulation of Gene_expression of SOD1 36 0.61 16.55 1.99
185 INT24464 Binding of Dlst 8 0.29 0.52 1.99
186 INT83332 Regulation of Gene_expression of TFRC 5 0.22 3.03 1.99
187 INT125080 Positive_regulation of Positive_regulation of TP53 21 0.58 16.16 1.98
188 INT191674 Gene_expression of Bag1 8 0.51 5.91 1.98
189 INT70526 Binding of CALR 11 0.35 7.09 1.97
190 INT21941 Regulation of CALR 7 0.53 3.88 1.96
191 INT98836 Transcription of Bax 6 0.69 5.04 1.96
192 INT146793 Positive_regulation of Tp53 30 0.70 32.93 1.94
193 INT98782 Gene_expression of Cdkn1b 70 0.75 36.43 1.9
194 INT134442 Transcription of Bax 14 0.67 7.6 1.9
195 INT15506 Localization of Cp 11 0.80 4.26 1.9
196 INT35370 Negative_regulation of Dlst 6 0.32 2.58 1.9
197 INT65855 Localization of TP53 18 0.76 17.08 1.89
198 INT135540 Negative_regulation of Bax 16 0.48 11.8 1.89
199 INT71807 Negative_regulation of Cp 18 0.58 8.9 1.88
200 INT56925 Negative_regulation of TSC1 54 0.52 63.39 1.87
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