GO:0051088

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Name PMA-inducible membrane protein ectodomain proteolysis
Categary Process
Go Slim No
Go Link GO:0051088
Unique Molecular Interactions 20
Total Molecular Interactions 24
Total Single Events 260
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for PMA-inducible membrane protein ectodomain proteolysis. They are ordered first by their pain relevance and then by number of times they were reported for PMA-inducible membrane protein ectodomain proteolysis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT117341 ADAM17 Positive_regulation of EGFR 1 0.16 3.56 0.82
2 INT102162 Binding of TNF and Adam17 1 0.14 0.88 0.78
3 INT102159 Binding of Adam17 and Mmp2 1 0.18 0.87 0.77
4 INT104301 Adam17 Regulation of Negative_regulation of Sell 1 0.39 0.58 0.69
5 INT235013 Binding of DSG1 and Adam17 1 0.07 1.34 0.26
6 INT234980 Positive_regulation of Egfr Positive_regulation of Adam17 1 0.09 1.33 0.26
7 INT259629 Binding of Adam17 and Timp3 1 0.01 0.19 0.11
8 INT353070 ADAM17 Positive_regulation of TNF 1 0.19 1.66 0.08
9 INT345245 Adam9 Regulation of Adam10 1 0.09 0.18 0.05
10 INT285396 Binding of Adam17 and R3hcc1 1 0.15 0.93 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for PMA-inducible membrane protein ectodomain proteolysis. They are ordered first by their pain relevance and then by number of times they were reported in PMA-inducible membrane protein ectodomain proteolysis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT130875 Gene_expression of ADAM17 13 0.78 15.46 6.41
2 INT104299 Negative_regulation of Adam17 18 0.47 12.03 4.39
3 INT134786 Gene_expression of Adam10 17 0.68 7.61 3.29
4 INT102157 Gene_expression of Adam17 3 0.58 4.17 2.86
5 INT117346 Positive_regulation of ADAM17 5 0.50 6.69 1.86
6 INT130874 Negative_regulation of Gene_expression of ADAM17 3 0.43 5.03 1.76
7 INT130332 Gene_expression of Adam17 14 0.50 4.84 1.56
8 INT78861 Negative_regulation of Transcription of Adam17 2 0.29 1.4 1.32
9 INT78859 Transcription of Adam17 2 0.47 1.39 1.31
10 INT234893 Positive_regulation of Adam17 4 0.38 3.78 1.22
11 INT132435 Negative_regulation of ADAM17 2 0.50 3.75 1.02
12 INT180100 Positive_regulation of Adam10 6 0.33 2 0.84
13 INT134789 Negative_regulation of Gene_expression of Adam10 1 0.30 1.22 0.78
14 INT138678 Transcription of ADAM17 1 0.69 4.9 0.56
15 INT327666 Regulation of Adam10 1 0.20 0 0.55
16 INT228248 Gene_expression of Adam9 4 0.45 1.63 0.51
17 INT138676 Localization of ADAM17 4 0.73 4.91 0.5
18 INT251556 Localization of Adam17 2 0.38 2 0.39
19 INT78862 Negative_regulation of Adam17 3 0.36 1.76 0.32
20 INT246100 Positive_regulation of Gene_expression of Adam10 4 0.61 1.2 0.3
21 INT187284 Positive_regulation of Gene_expression of Adam17 3 0.20 1.32 0.29
22 INT180101 Phosphorylation of Adam17 3 0.37 0.25 0.24
23 INT78865 Localization of Adam17 1 0.43 0.34 0.23
24 INT138679 Regulation of ADAM17 1 0.19 1.13 0.16
25 INT138680 Binding of ADAM17 1 0.36 1.42 0.16
26 INT237404 Regulation of Positive_regulation of Adam10 1 0.30 0.83 0.16
27 INT169349 Regulation of Adam17 1 0.37 0.97 0.13
28 INT138677 Negative_regulation of Transcription of ADAM17 1 0.42 1.18 0.1
29 INT187285 Protein_catabolism of Adam17 1 0.12 0.94 0.09
30 INT356064 Regulation of Negative_regulation of Adam17 1 0.23 0.24 0.08
31 INT356054 Regulation of Phosphorylation of Adam17 1 0.20 0.25 0.08
32 INT180096 Positive_regulation of Phosphorylation of Adam17 1 0.07 0 0.08
33 INT345234 Positive_regulation of Transcription of Adam9 1 0.20 0.19 0.08
34 INT345238 Transcription of Adam9 1 0.23 0.19 0.08
35 INT356058 Negative_regulation of Adam10 1 0.23 0.8 0.07
36 INT345241 Localization of Adam9 1 0.30 0.16 0.07
37 INT180108 Binding of Adam10 1 0.05 0 0.05
38 INT180094 Binding of Adam17 1 0.06 0 0.05
39 INT345239 Positive_regulation of Gene_expression of Adam9 1 0.25 0 0.05
40 INT356055 Localization of Adam10 1 0.40 0.5 0.05
41 INT356076 Negative_regulation of Localization of Adam10 1 0.23 0.51 0.05
42 INT356057 Positive_regulation of Positive_regulation of Adam10 1 0.32 0.25 0.05
43 INT345243 Protein_catabolism of Adam10 1 0.44 0 0
44 INT285394 Binding of Adam17 1 0.31 0.93 0
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