GO:0051090

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Name regulation of sequence-specific DNA binding transcription factor activity
Categary Process
Go Slim No
Go Link GO:0051090
Unique Molecular Interactions 907
Total Molecular Interactions 1108
Total Single Events 9710
Pain Genes Associated 40

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for regulation of sequence-specific DNA binding transcription factor activity. They are ordered first by their pain relevance and then by number of times they were reported for regulation of sequence-specific DNA binding transcription factor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT190167 Binding of JUN and MMP12 1 0.26 0.82 2.76
2 INT223866 Ltp Positive_regulation of Positive_regulation of Mapk1 2 0.46 0.75 2.61
3 INT238914 Positive_regulation of CNR1 Positive_regulation of Phosphorylation of MAPK1 1 0.19 3.22 2.35
4 INT139723 PROC Positive_regulation of MAPK8 1 0.01 2.98 2.33
5 INT281084 Prkaca Positive_regulation of Mapk1 2 0.25 0 2.06
6 INT94203 SP5 Positive_regulation of FOS 1 0.25 1.41 1.72
7 INT105112 Plat Positive_regulation of JUN 1 0.01 1.55 1.58
8 INT144280 ACP1 Negative_regulation of Phosphorylation of MAPK1 1 0.37 0.78 1.56
9 INT169800 Negative_regulation of Adrbk1 Positive_regulation of Positive_regulation of Mapk1 1 0.39 1.04 1.45
10 INT261831 Mapk1 Negative_regulation of Hspg2 1 0.00 1.26 1.42
11 INT148450 Gene_expression of Inhbe Positive_regulation of Mapk1 1 0.07 1.35 1.41
12 INT161670 H2-M3 Positive_regulation of Positive_regulation of Mapk1 1 0.14 0.73 1.41
13 INT134679 FSCN1 Positive_regulation of MAPK8 1 0.01 0.56 1.39
14 INT106071 Positive_regulation of Oprl1 Positive_regulation of MAPK3 1 0.12 0.16 1.34
15 INT192080 Foxm1 Positive_regulation of Cnr1 2 0.14 0.72 1.3
16 INT70181 PRCP Positive_regulation of FOS 1 0.58 0.36 1.26
17 INT139724 PROC Positive_regulation of MAPK14 1 0.00 1.57 1.25
18 INT166388 Binding of Gnb2l1 and Mapk1 1 0.49 0.49 1.21
19 INT139736 Htr1a Positive_regulation of Mapk3 1 0.54 0.13 1.19
20 INT330379 Gene_expression of IL10 Negative_regulation of Positive_regulation of MAPK14 1 0.00 1.95 1.18
21 INT121191 KCNMA1 Positive_regulation of Phosphorylation of MAPK1 1 0.06 0.61 1.18
22 INT169557 Cacna1h Positive_regulation of Mapk1 1 0.07 0.91 1.17
23 INT238916 CNR1 Positive_regulation of Phosphorylation of MAPK1 1 0.19 1.61 1.17
24 INT150191 CEACAM3 Positive_regulation of Gene_expression of FOS 1 0.34 0.14 1.16
25 INT111221 MMEL1 Negative_regulation of HMOX1 1 0.01 1 1.16
26 INT161510 Tlr4 Positive_regulation of Mapk1 1 0.14 0.3 1.16
27 INT231769 TNF Negative_regulation of Gene_expression of HMOX1 1 0.26 4.75 1.15
28 INT164378 MAPK3 Positive_regulation of Transcription of PDYN 1 0.50 0.2 1.09
29 INT164382 MAPK3 Positive_regulation of Gene_expression of Fos 1 0.75 0.2 1.08
30 INT164383 Positive_regulation of MAPK3 Positive_regulation of Gene_expression of Fos 1 0.54 0.2 1.08
31 INT105109 Cxcl12 Positive_regulation of JUN 1 0.01 1.07 1.05
32 INT307047 Foxm1 Positive_regulation of Casp3 1 0.11 0.06 1.03
33 INT101067 MAP3K15 Positive_regulation of MAPK1 1 0.21 0.47 1.03
34 INT101065 MAP3K15 Positive_regulation of JUN 1 0.43 0.46 1.02
35 INT229914 Egr1 Positive_regulation of Phosphorylation of Mapk3 1 0.46 1.03 1.02
36 INT113453 Ngf Positive_regulation of JUN 1 0.27 0.6 1.01
37 INT140652 IGF1 Positive_regulation of Phosphorylation of MAPK1 1 0.26 0.63 0.98
38 INT94206 SP5 Regulation of Gene_expression of FOS 1 0.22 0.7 0.98
39 INT100018 TNF Positive_regulation of MAPK1 3 0.24 1.56 0.94
40 INT152390 Negative_regulation of Binding of JUN and OPRM1 1 0.13 0.14 0.94
41 INT152387 Binding of JUN and OPRM1 1 0.15 0.14 0.94
42 INT144281 ACP1 Negative_regulation of Positive_regulation of MAPK1 1 0.27 0.58 0.94
43 INT149390 Foxm1 Positive_regulation of Trpa1 1 0.28 0.31 0.94
44 INT144285 ACP1 Negative_regulation of MAPK1 1 0.37 0.58 0.93
45 INT223871 Ltp Positive_regulation of Gene_expression of Mapk1 1 0.33 0 0.93
46 INT302828 Mapkapk5 Positive_regulation of Mapk1 1 0.07 1.38 0.91
47 INT135446 Map2k1 Positive_regulation of Mapk3 1 0.54 0.25 0.91
48 INT343918 IgG Positive_regulation of Phosphorylation of MAPK1 1 0.01 3.57 0.91
49 INT147474 Nfe2l2 Positive_regulation of Hmox1 1 0.43 0.38 0.9
50 INT249347 Binding of FOS and JUN 4 0.19 6.15 0.89
51 INT209928 IL1B Positive_regulation of MAPK14 2 0.15 1.69 0.87
52 INT188196 LIF Regulation of MAPK1 1 0.21 2.26 0.87
53 INT97738 Mdk Positive_regulation of Mapk3 1 0.08 0.66 0.87
54 INT188214 OSM Regulation of MAPK1 1 0.20 2.27 0.87
55 INT97735 Trib3 Positive_regulation of Mapk3 1 0.05 0.66 0.87
56 INT161308 POMC Negative_regulation of Positive_regulation of JUN 1 0.12 0.27 0.86
57 INT124878 Gnat3 Negative_regulation of Gene_expression of FOS 1 0.09 0.16 0.85
58 INT190183 MAPK1 Regulation of CDCP1 1 0.00 1.19 0.85
59 INT161307 JUN Positive_regulation of IL2 1 0.14 0.25 0.84
60 INT124877 Gnat3 Negative_regulation of FOS 1 0.09 0.15 0.82
61 INT124876 Gnat3 Negative_regulation of Positive_regulation of FOS 1 0.09 0.15 0.82
62 INT262572 Ngf Positive_regulation of Mapk1 2 0.04 0.52 0.81
63 INT341367 CRX Positive_regulation of Positive_regulation of FOS 1 0.04 0.83 0.8
64 INT190182 JUN Positive_regulation of MMP12 1 0.34 0.08 0.8
65 INT161520 H2-M3 Regulation of Positive_regulation of Mapk1 1 0.09 0.47 0.79
66 INT132977 Tac1 Positive_regulation of Mapk1 1 0.06 0.17 0.79
67 INT117909 Mastl Positive_regulation of Mapk1 1 0.04 0 0.79
68 INT158684 MAPK8 Positive_regulation of Gene_expression of BCL2L11 1 0.51 0.44 0.78
69 INT346234 MAP2K6 Positive_regulation of MAPK14 1 0.44 1.65 0.77
70 INT163830 ERBB2 Positive_regulation of MAPK1 1 0.06 1.63 0.76
71 INT155096 Stat3 Regulation of Mapk3 1 0.36 0.45 0.76
72 INT81299 Ifng Positive_regulation of Gene_expression of Hmox1 1 0.52 0.75 0.76
73 INT151809 JUN Positive_regulation of Positive_regulation of OPRM1 1 0.32 0 0.74
74 INT190169 Regulation of JUN Positive_regulation of Localization of MMP12 1 0.30 0.07 0.74
75 INT186445 Creb1 Regulation of Transcription of FOS 1 0.49 0.44 0.73
76 INT186443 Phosphorylation of Creb1 Regulation of Transcription of FOS 1 0.49 0.44 0.73
77 INT186444 Creb1 Regulation of FOS 1 0.49 0.43 0.72
78 INT186442 Phosphorylation of Creb1 Regulation of FOS 1 0.49 0.43 0.72
79 INT168911 Grm5 Regulation of Mapk3 1 0.17 0.78 0.71
80 INT166386 Mapk1 Regulation of Gene_expression of Gnb2l1 1 0.46 0.25 0.7
81 INT320633 Positive_regulation of MAPK1 Regulation of BCL2 1 0.04 1.21 0.7
82 INT194685 MAPK1 Regulation of Gene_expression of IL10 1 0.06 1.18 0.7
83 INT320634 Positive_regulation of MAPK1 Regulation of PBX2 1 0.03 1.21 0.7
84 INT66581 Binding of JUN and Rare2 1 0.00 0.07 0.69
85 INT66582 Binding of FOS and Rare2 1 0.00 0.07 0.69
86 INT223868 Mapk1 Positive_regulation of Creb1 2 0.17 0.34 0.68
87 INT99743 Olr1742 Regulation of Gene_expression of Hmox1 1 0.00 0 0.68
88 INT223876 Mapk1 Positive_regulation of Atf6b 1 0.10 0 0.68
89 INT214595 Binding of FOXC1 and TIMP1 1 0.02 0.96 0.66
90 INT211915 Fig4 Positive_regulation of Mapk3 1 0.12 0.25 0.66
91 INT86519 Binding of Hmox1 and Hmox2 1 0.08 0.1 0.66
92 INT62059 Positive_regulation of SCN5A Positive_regulation of Gene_expression of FOS 1 0.01 0.42 0.66
93 INT191332 AMPH Positive_regulation of Mapk1 1 0.76 0 0.66
94 INT124477 MAP2K1 Positive_regulation of Positive_regulation of MAPK1 1 0.12 1.35 0.65
95 INT103868 IFNG Positive_regulation of Hmox1 1 0.09 0.83 0.65
96 INT148173 Positive_regulation of Grm5 Positive_regulation of Phosphorylation of Mapk1 1 0.01 0.45 0.65
97 INT99744 Calca Positive_regulation of Positive_regulation of Hmox1 1 0.48 0 0.64
98 INT103870 IRF6 Positive_regulation of Hmox1 1 0.14 0.83 0.64
99 INT158685 ROS1 Regulation of Positive_regulation of MAPK8 1 0.21 0.39 0.64
100 INT169296 PTPLA Positive_regulation of MAPK3 1 0.10 0.15 0.63
101 INT169295 PTPLA Positive_regulation of MAPK8 1 0.10 0.15 0.63
102 INT281092 Adcy1 Positive_regulation of Mapk1 1 0.21 0 0.63
103 INT281090 Prkacb Positive_regulation of Mapk1 1 0.06 0 0.62
104 INT177979 Binding of STAT3 and FOXI2 1 0.00 1.83 0.61
105 INT81916 HSF1 Positive_regulation of FOS 1 0.76 0.66 0.59
106 INT223158 Mapk3 Regulation of Gene_expression of Mapk14 1 0.48 1.33 0.59
107 INT81918 HSF1 Negative_regulation of FOS 1 0.64 0.66 0.59
108 INT291262 Positive_regulation of INS Positive_regulation of Mapk1 1 0.03 1.78 0.58
109 INT291258 INS Positive_regulation of Mapk1 1 0.04 1.77 0.58
110 INT115146 MAPK1 Positive_regulation of EGR1 3 0.13 2.43 0.57
111 INT148172 Mapk1 Positive_regulation of Phosphorylation of Kcnd2 1 0.49 0.55 0.57
112 INT81303 Tlr4 Positive_regulation of Gene_expression of Hmox1 1 0.03 0.55 0.56
113 INT278694 TNF Positive_regulation of MAPK14 1 0.03 0.79 0.56
114 INT278689 TNF Positive_regulation of MAPK8 1 0.04 0.79 0.56
115 INT201949 CXCL10 Positive_regulation of Phosphorylation of MAPK1 1 0.15 0.79 0.55
116 INT121994 EGF Positive_regulation of Positive_regulation of MAPK1 1 0.25 0 0.55
117 INT99486 OPRM1 Positive_regulation of MAPK3 1 0.22 0 0.55
118 INT343913 Binding of FOS and Smad3 1 0.19 0.92 0.54
119 INT323146 PRKCA Positive_regulation of MAPK1 1 0.02 0 0.54
120 INT85125 IL3 Positive_regulation of MAPK1 1 0.30 0.81 0.53
121 INT270044 Il10 Positive_regulation of Positive_regulation of Hmox1 1 0.20 1.59 0.53
122 INT85121 CSF2 Positive_regulation of MAPK1 1 0.07 0.8 0.53
123 INT85115 IL5 Positive_regulation of MAPK1 1 0.14 0.81 0.53
124 INT106394 MAPK3 Positive_regulation of ADRBK1 1 0.48 0.06 0.53
125 INT171909 MAPK8 Positive_regulation of Gene_expression of MAPK1 1 0.08 1.55 0.52
126 INT171910 MAPK1 Positive_regulation of MAPK9 1 0.10 1.55 0.52
127 INT201939 CXCL10 Positive_regulation of MAPK1 1 0.11 0.72 0.52
128 INT171906 MAPK1 Positive_regulation of Gene_expression of MAPK14 1 0.08 1.55 0.52
129 INT171914 MAPK8IP3 Positive_regulation of Gene_expression of MAPK1 1 0.06 1.55 0.52
130 INT122872 SEMA6A Positive_regulation of MAPK1 1 0.56 0 0.52
131 INT131368 MAPK1 Positive_regulation of Bcar3 1 0.00 0.37 0.51
132 INT138353 Foxm1 Positive_regulation of Phosphorylation of Trpv1 1 0.10 0.31 0.51
133 INT131371 MAPK3 Positive_regulation of Il4 1 0.02 0.37 0.51
134 INT131367 MAPK3 Positive_regulation of Bcar3 1 0.00 0.37 0.51
135 INT138352 Foxm1 Positive_regulation of Trpa1 1 0.05 0.33 0.51
136 INT131370 MAPK3 Positive_regulation of Gene_expression of Il4 1 0.02 0.37 0.51
137 INT131369 MAPK1 Positive_regulation of Il4 1 0.01 0.37 0.51
138 INT350076 Positive_regulation of Hmox1 Negative_regulation of Gene_expression of Ptger2 1 0.02 1.29 0.5
139 INT206010 Foxm1 Positive_regulation of Gene_expression of Il18 1 0.03 0.72 0.5
140 INT194676 Negative_regulation of MAPK1 Negative_regulation of Gene_expression of IL10 1 0.05 0.34 0.5
141 INT86088 Foxm1 Positive_regulation of Binding of Crygs 1 0.04 0 0.49
142 INT115184 Regulation of CASP1 Positive_regulation of MAPK9 1 0.09 0 0.49
143 INT86089 Foxm1 Regulation of Binding of Crygs 1 0.02 0 0.49
144 INT145435 Binding of CPOX and HMOX1 1 0.01 0.42 0.49
145 INT115183 CASP1 Positive_regulation of Positive_regulation of MAPK9 1 0.16 0 0.48
146 INT102553 HGF Positive_regulation of Phosphorylation of MAPK1 1 0.40 0.49 0.48
147 INT115185 CASP1 Positive_regulation of MAPK9 1 0.15 0 0.48
148 INT116932 PTK2 Negative_regulation of Positive_regulation of MAPK8 1 0.35 0.17 0.48
149 INT145434 Binding of HMOX1 and PTGS2 1 0.02 0.41 0.47
150 INT102552 HGF Positive_regulation of MAPK3 1 0.38 0.47 0.47
151 INT148466 Ccl4 Positive_regulation of Hmox1 1 0.28 0.06 0.47
152 INT185917 Binding of AR and MAPK1 1 0.07 0.5 0.47
153 INT102555 HGF Positive_regulation of MAPK1 1 0.38 0.47 0.47
154 INT117703 OPRK1 Positive_regulation of Positive_regulation of JUN 1 0.01 0.08 0.47
155 INT265646 Binding of Mapk1 and Mapk14 1 0.01 1.53 0.46
156 INT254198 Mapk1 Positive_regulation of Mapk8 1 0.01 0.87 0.46
157 INT254216 Mapk14 Positive_regulation of Mapk1 1 0.02 0.87 0.46
158 INT116928 PTK2 Positive_regulation of JUN 1 0.20 0.15 0.46
159 INT116933 SRC Positive_regulation of JUN 1 0.33 0.15 0.46
160 INT116929 OPRK1 Positive_regulation of JUN 1 0.28 0.15 0.46
161 INT254222 Mapk1 Positive_regulation of Mapk14 1 0.02 0.86 0.46
162 INT108332 EGF Positive_regulation of Phosphorylation of MAPK1 5 0.48 1.85 0.45
163 INT242402 Negative_regulation of Bdkrb1 Positive_regulation of Hmox1 1 0.17 1.44 0.45
164 INT103871 Negative_regulation of IRF6 Positive_regulation of Hmox1 1 0.12 0.61 0.45
165 INT190870 BDNF Positive_regulation of Phosphorylation of Mapk1 1 0.12 0.54 0.44
166 INT165677 NFE2L2 Negative_regulation of Positive_regulation of HMOX1 1 0.40 0.32 0.44
167 INT343846 MAPK1 Positive_regulation of FOS 1 0.04 1.29 0.44
168 INT104016 RPGR Positive_regulation of Gene_expression of FOS 1 0.16 0 0.43
169 INT223863 Positive_regulation of Mapk1 Positive_regulation of Positive_regulation of Ltp 1 0.31 0 0.43
170 INT103132 Positive_regulation of DCSTAMP Positive_regulation of JUN 1 0.03 0.73 0.43
171 INT189197 RASGRP1 Positive_regulation of JUN 1 0.07 1.26 0.43
172 INT278950 MAPK8 Negative_regulation of Localization of EPHB2 1 0.25 0.47 0.43
173 INT188211 IL6 Regulation of MAPK1 1 0.16 1.13 0.43
174 INT265647 Binding of Ephb1 and Mapk1 1 0.00 1.48 0.43
175 INT278964 MAPK14 Negative_regulation of Localization of EPHB2 1 0.15 0.47 0.43
176 INT116931 OPRK1 Regulation of MAPK8 1 0.31 0.07 0.43
177 INT165678 NFE2L2 Negative_regulation of HMOX1 1 0.40 0.31 0.43
178 INT103129 DCSTAMP Positive_regulation of JUN 1 0.03 0.72 0.43
179 INT106396 DYT10 Positive_regulation of MAPK3 1 0.50 0 0.42
180 INT238913 MAPK3 Regulation of Positive_regulation of MAPK1 1 0.11 0.39 0.42
181 INT161521 Negative_regulation of H2-M3 Positive_regulation of Mapk1 1 0.14 0.41 0.42
182 INT194722 Negative_regulation of MAPK1 Negative_regulation of Gene_expression of CRP 1 0.09 1.49 0.41
183 INT116938 Positive_regulation of GLI2 Positive_regulation of MAPK8 1 0.10 0.07 0.41
184 INT274864 Negative_regulation of Mapk1 Negative_regulation of Gene_expression of TNF 1 0.05 1.15 0.41
185 INT161522 H2-M3 Positive_regulation of Mapk1 1 0.15 0.41 0.41
186 INT274867 Negative_regulation of Mapk1 Negative_regulation of TNF 1 0.03 1.15 0.41
187 INT261652 Binding of MAPK1 and PSEN1 1 0.22 1.25 0.41
188 INT124260 Plat Positive_regulation of Mapk1 1 0.14 0.81 0.41
189 INT116936 Positive_regulation of GLI2 Positive_regulation of JUN 1 0.12 0.07 0.41
190 INT162041 F2 Positive_regulation of Positive_regulation of FOS 1 0.13 1.14 0.41
191 INT194705 Negative_regulation of MAPK1 Negative_regulation of Positive_regulation of IK 1 0.00 1.46 0.41
192 INT87605 Binding of FOS and Penk 1 0.07 0.78 0.4
193 INT108197 AKT1 Regulation of JUN 1 0.29 0.25 0.4
194 INT113474 MAPK1 Negative_regulation of TNF 1 0.13 0.23 0.4
195 INT216881 Binding of Apoc4 and Hmox1 1 0.01 1.78 0.4
196 INT87604 FOS Regulation of Penk 1 0.09 0.76 0.39
197 INT152237 Mapk1 Positive_regulation of Localization of Tlr4 1 0.33 0.13 0.39
198 INT87603 Binding of FOS and Jund 1 0.03 0.77 0.39
199 INT147473 Nfe2l2 Positive_regulation of Gene_expression of Hmox1 1 0.74 0.49 0.39
200 INT152239 Mapk1 Positive_regulation of Localization of Nfkb1 1 0.29 0.13 0.39

Single Events

The table below shows the top 100 pain related interactions that have been reported for regulation of sequence-specific DNA binding transcription factor activity. They are ordered first by their pain relevance and then by number of times they were reported in regulation of sequence-specific DNA binding transcription factor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT95787 Positive_regulation of Mapk1 568 0.70 226.51 220.94
2 INT6665 Gene_expression of FOS 520 0.77 165.31 217.66
3 INT17459 Positive_regulation of Gene_expression of FOS 182 0.67 53.45 96.38
4 INT71789 Positive_regulation of MAPK1 396 0.70 234.44 89.27
5 INT92434 Phosphorylation of Mapk1 287 0.82 91.65 83.46
6 INT5356 Positive_regulation of FOS 153 0.69 54.21 56.74
7 INT17458 Negative_regulation of Gene_expression of FOS 98 0.57 36.77 55.69
8 INT71786 Phosphorylation of MAPK1 256 0.82 110.09 46.17
9 INT92437 Positive_regulation of Phosphorylation of Mapk1 113 0.70 32.19 40.29
10 INT114751 Gene_expression of Mapk1 137 0.76 60.14 39.98
11 INT102611 Negative_regulation of Positive_regulation of Mapk1 74 0.58 35.57 39.37
12 INT48933 Gene_expression of Mapk3 93 0.75 44.39 37.92
13 INT80690 Positive_regulation of MAPK8 223 0.68 125.63 36.75
14 INT48924 Positive_regulation of Mapk3 107 0.67 50.53 34.05
15 INT73982 Gene_expression of Hmox1 141 0.78 119.43 32.17
16 INT86780 Positive_regulation of Hmox1 145 0.70 117.09 31.18
17 INT117112 Negative_regulation of Mapk1 87 0.56 40.34 31.18
18 INT72375 Phosphorylation of Mapk3 87 0.80 43.66 30.27
19 INT83708 Negative_regulation of MAPK1 156 0.57 84.93 27.85
20 INT17331 Positive_regulation of JUN 132 0.69 60.4 27.03
21 INT48979 Regulation of Gene_expression of FOS 52 0.61 14.4 25.95
22 INT95788 Positive_regulation of Positive_regulation of Mapk1 83 0.69 24.75 25.84
23 INT12124 Gene_expression of MAPK1 141 0.75 82.4 25.58
24 INT71781 Phosphorylation of MAPK3 62 0.80 27.73 23.73
25 INT86534 Positive_regulation of MAPK14 81 0.62 57.81 23.62
26 INT69322 Negative_regulation of MAPK14 70 0.54 42.92 22.71
27 INT171924 Gene_expression of MAPK14 60 0.65 54.38 21.68
28 INT91462 Positive_regulation of Phosphorylation of MAPK1 99 0.67 40.28 18.99
29 INT71787 Positive_regulation of MAPK3 37 0.67 17.5 17.88
30 INT80223 Positive_regulation of Hmox1 128 0.68 77.71 17.64
31 INT116950 Negative_regulation of MAPK8 103 0.57 44.48 17.53
32 INT76406 Gene_expression of Hmox1 140 0.78 85.86 17.15
33 INT109929 Phosphorylation of MAPK8 102 0.81 39.98 16.54
34 INT95790 Regulation of Mapk1 55 0.61 21.17 16.31
35 INT111462 Negative_regulation of Phosphorylation of Mapk1 45 0.57 19.49 15.59
36 INT75531 Regulation of MAPK1 70 0.61 34.39 15.42
37 INT60197 Gene_expression of JUN 90 0.78 42.32 14.61
38 INT80688 Positive_regulation of Positive_regulation of MAPK1 72 0.69 39.35 14.11
39 INT80228 Positive_regulation of Gene_expression of Hmox1 68 0.70 62.88 14.01
40 INT111529 Phosphorylation of Mapk3 41 0.80 21.14 13.72
41 INT80685 Gene_expression of MAPK8 90 0.72 51.91 13.36
42 INT15246 Regulation of FOS 32 0.60 15.34 12.94
43 INT48927 Regulation of Mapk3 25 0.60 14.06 12.82
44 INT116528 Gene_expression of HMOX1 106 0.78 86.13 12.8
45 INT150676 Positive_regulation of Gene_expression of Mapk1 30 0.45 10.06 12.37
46 INT119396 Regulation of Positive_regulation of Mapk1 22 0.61 7.88 12.25
47 INT75525 Negative_regulation of Positive_regulation of MAPK1 40 0.59 25.15 11.15
48 INT111223 Positive_regulation of HMOX1 47 0.70 39.14 10.92
49 INT87451 Positive_regulation of Mapk3 34 0.67 12.82 10.38
50 INT110178 Phosphorylation of MAPK14 40 0.68 19.38 10.37
51 INT60198 Binding of JUN 54 0.48 11.56 10.27
52 INT94196 Negative_regulation of Phosphorylation of MAPK1 60 0.59 31.64 9.16
53 INT48978 Negative_regulation of FOS 41 0.57 11.94 9.14
54 INT111133 Negative_regulation of Mapk3 31 0.57 10.89 8.9
55 INT17333 Positive_regulation of Positive_regulation of FOS 17 0.67 6.06 8.4
56 INT71785 Gene_expression of MAPK3 22 0.75 11.35 8.21
57 INT82450 Negative_regulation of Hmox1 33 0.55 19.07 8.12
58 INT82762 Positive_regulation of Positive_regulation of Mapk3 23 0.67 7.72 7.91
59 INT72372 Positive_regulation of Phosphorylation of Mapk3 30 0.67 13.6 7.69
60 INT91618 Positive_regulation of Phosphorylation of MAPK3 21 0.67 7.99 7.65
61 INT80686 Positive_regulation of Positive_regulation of MAPK8 42 0.68 26.95 7.63
62 INT47848 Negative_regulation of Positive_regulation of FOS 14 0.57 3.78 7.63
63 INT81293 Positive_regulation of Gene_expression of Hmox1 53 0.70 41.54 7.25
64 INT75497 Regulation of JUN 28 0.61 11.04 7.09
65 INT60196 Binding of FOS 33 0.47 13.11 6.95
66 INT68653 Negative_regulation of JUN 34 0.58 14.27 6.56
67 INT50337 Negative_regulation of Foxm1 24 0.43 11.12 6.48
68 INT5847 Transcription of FOS 31 0.69 11.11 6.41
69 INT94197 Negative_regulation of Phosphorylation of MAPK3 13 0.57 5.51 6.18
70 INT48926 Positive_regulation of Gene_expression of Mapk3 12 0.46 6.02 6.13
71 INT130111 Regulation of Positive_regulation of MAPK1 14 0.36 11.01 5.9
72 INT82451 Negative_regulation of HMOX1 18 0.51 13.29 5.74
73 INT55513 Binding of Foxm1 19 0.37 2.37 5.54
74 INT71779 Positive_regulation of Gene_expression of MAPK1 27 0.47 21.41 5.39
75 INT99487 Negative_regulation of MAPK3 15 0.57 7.13 5.39
76 INT109928 Negative_regulation of Positive_regulation of MAPK8 19 0.42 10.42 5.23
77 INT83735 Gene_expression of Foxm1 41 0.77 22.9 5.07
78 INT116527 Positive_regulation of Gene_expression of HMOX1 29 0.70 25.79 4.87
79 INT54911 Localization of FOS 20 0.78 3.27 4.56
80 INT117920 Regulation of MAPK14 14 0.38 8.75 4.31
81 INT111535 Negative_regulation of Phosphorylation of Mapk3 9 0.57 6.39 4.31
82 INT75523 Regulation of MAPK8 21 0.33 11.18 4.28
83 INT64338 Negative_regulation of Hmox1 16 0.56 12.72 4.2
84 INT109935 Positive_regulation of Phosphorylation of MAPK8 35 0.68 13.13 4.18
85 INT158416 Localization of Mapk1 19 0.67 5.32 4.18
86 INT117921 Positive_regulation of Positive_regulation of MAPK14 9 0.44 9.93 4.18
87 INT67936 Transcription of JUN 18 0.52 9.52 4.13
88 INT110181 Negative_regulation of Phosphorylation of MAPK8 20 0.57 9.43 4.06
89 INT112782 Localization of Mapk3 8 0.78 1.87 3.98
90 INT132103 Positive_regulation of Gene_expression of MAPK8 26 0.46 16.54 3.94
91 INT97096 Regulation of Hmox1 18 0.61 6.42 3.9
92 INT113924 Binding of Mapk1 27 0.38 8.64 3.84
93 INT110180 Phosphorylation of JUN 23 0.80 11.21 3.83
94 INT123827 Positive_regulation of Phosphorylation of Mapk3 10 0.67 5.22 3.82
95 INT94291 Regulation of Gene_expression of Mapk3 4 0.40 3.05 3.8
96 INT80224 Regulation of Hmox1 19 0.32 10.53 3.52
97 INT23220 Positive_regulation of FOXG1 10 0.43 2.86 3.49
98 INT129751 Regulation of Phosphorylation of Mapk3 11 0.55 3.91 3.35
99 INT135773 Negative_regulation of Gene_expression of HMOX1 31 0.53 28.31 3.32
100 INT102634 Transcription of Hmox1 22 0.62 4.5 3.3
101 INT97737 Negative_regulation of Phosphorylation of Mapk3 9 0.57 5.64 3.3
102 INT109914 Positive_regulation of MAPK9 16 0.56 7.64 3.27
103 INT81453 Positive_regulation of Gene_expression of JUN 18 0.50 9.39 3.23
104 INT171368 Regulation of Phosphorylation of Mapk1 14 0.61 4.77 3.14
105 INT71783 Positive_regulation of Gene_expression of MAPK3 9 0.59 4.59 3.05
106 INT68651 Negative_regulation of Positive_regulation of JUN 11 0.58 4.28 3.04
107 INT87288 Positive_regulation of Positive_regulation of MAPK3 5 0.67 1.62 3.04
108 INT173179 Binding of MAPK14 13 0.29 4.51 2.92
109 INT9242 Negative_regulation of FOXG1 13 0.40 1.43 2.86
110 INT50335 Positive_regulation of Foxm1 20 0.69 5.11 2.81
111 INT127904 Negative_regulation of Gene_expression of Hmox1 11 0.42 9.54 2.8
112 INT108358 Phosphorylation of FOS 12 0.80 6.33 2.79
113 INT145821 Negative_regulation of Gene_expression of Mapk1 16 0.41 8.05 2.77
114 INT81291 Regulation of Gene_expression of Hmox1 11 0.60 8.78 2.46
115 INT110179 Negative_regulation of Phosphorylation of MAPK14 11 0.36 5.25 2.38
116 INT123682 Localization of JUN 8 0.50 4.15 2.38
117 INT87284 Negative_regulation of Positive_regulation of MAPK3 7 0.41 2.65 2.38
118 INT113203 Regulation of Foxm1 8 0.34 7.5 2.36
119 INT48980 Positive_regulation of Transcription of FOS 10 0.67 3.07 2.34
120 INT23219 Regulation of FOXG1 8 0.22 1.32 2.34
121 INT60199 Positive_regulation of Binding of JUN 5 0.49 1.3 2.34
122 INT186116 Regulation of Gene_expression of MAPK1 9 0.44 5.85 2.32
123 INT109908 Localization of MAPK8 10 0.73 3.86 2.14
124 INT173647 Positive_regulation of Gene_expression of MAPK14 15 0.39 7.54 2.05
125 INT109906 Localization of MAPK1 12 0.54 1.68 2.01
126 INT83709 Negative_regulation of Gene_expression of MAPK1 12 0.41 6.57 2.01
127 INT110925 Positive_regulation of Positive_regulation of JUN 14 0.49 6.22 1.98
128 INT121781 Regulation of Mapk3 5 0.44 1.96 1.98
129 INT130208 Positive_regulation of Phosphorylation of JUN 4 0.38 3.07 1.92
130 INT118683 Regulation of Phosphorylation of MAPK3 3 0.44 2.92 1.82
131 INT109921 Phosphorylation of MAPK9 9 0.67 5.07 1.81
132 INT90026 Gene_expression of FOXI2 5 0.03 0.98 1.79
133 INT82760 Negative_regulation of Positive_regulation of Mapk3 7 0.57 3.18 1.78
134 INT99742 Negative_regulation of Gene_expression of Hmox1 12 0.58 9.94 1.77
135 INT87282 Regulation of MAPK3 9 0.60 7.61 1.65
136 INT173173 Regulation of Positive_regulation of MAPK14 6 0.38 2.59 1.64
137 INT149994 Gene_expression of Mapk3 16 0.65 3.45 1.62
138 INT80227 Regulation of Gene_expression of Hmox1 12 0.44 11.04 1.61
139 INT169461 Regulation of Gene_expression of Mapk1 7 0.44 1.64 1.61
140 INT91232 Regulation of Positive_regulation of Hmox1 5 0.45 2.43 1.55
141 INT182297 Positive_regulation of Phosphorylation of MAPK14 7 0.42 3.36 1.53
142 INT82761 Regulation of Positive_regulation of Mapk3 3 0.40 1.34 1.52
143 INT130019 Regulation of Phosphorylation of MAPK1 6 0.49 3.6 1.5
144 INT103305 Positive_regulation of Positive_regulation of Hmox1 8 0.49 4.81 1.49
145 INT132886 Negative_regulation of Positive_regulation of Mapk3 2 0.30 1.27 1.49
146 INT100420 Regulation of HMOX1 10 0.35 6.68 1.48
147 INT171029 Positive_regulation of Transcription of JUN 4 0.14 2.87 1.48
148 INT157362 Negative_regulation of MAPK9 7 0.35 4.27 1.44
149 INT173654 Localization of MAPK14 12 0.62 3.16 1.43
150 INT190646 Regulation of Regulation of Mapk1 1 0.30 1.16 1.43
151 INT165680 Transcription of HMOX1 7 0.71 11.2 1.41
152 INT104027 Negative_regulation of Negative_regulation of MAPK1 6 0.56 2.87 1.35
153 INT127283 Regulation of Gene_expression of HMOX1 14 0.61 11.8 1.28
154 INT91320 Localization of Hmox1 8 0.81 4.06 1.28
155 INT68652 Regulation of Positive_regulation of JUN 4 0.54 4.95 1.26
156 INT125079 Negative_regulation of Gene_expression of MAPK8 9 0.39 4.87 1.25
157 INT130207 Phosphorylation of ATF2 5 0.60 1.34 1.25
158 INT120764 Negative_regulation of Binding of JUN 7 0.25 2.65 1.23
159 INT112823 Negative_regulation of Positive_regulation of MAPK14 5 0.36 1.49 1.22
160 INT84130 Gene_expression of Foxo1 1 0.26 0.97 1.22
161 INT39711 Negative_regulation of FOXC1 4 0.41 4.29 1.2
162 INT81311 Gene_expression of FOXC1 9 0.44 3.46 1.18
163 INT239028 Negative_regulation of Foxo4 1 0.42 2.75 1.16
164 INT157364 Positive_regulation of Phosphorylation of MAPK9 3 0.56 2.33 1.15
165 INT115831 Transcription of Hmox1 16 0.66 5.31 1.14
166 INT238919 Regulation of Gene_expression of MAPK3 3 0.16 1.6 1.13
167 INT17332 Regulation of Positive_regulation of FOS 6 0.44 0.78 1.11
168 INT75503 Regulation of Gene_expression of JUN 6 0.21 2.87 1.11
169 INT69394 Positive_regulation of Binding of FOS 6 0.49 3.54 1.11
170 INT199187 Localization of Hmox1 2 0.78 3.36 1.11
171 INT48982 Positive_regulation of Regulation of FOS 2 0.45 0.15 1.11
172 INT156427 Localization of FOXC1 2 0.73 1.36 1.07
173 INT138349 Phosphorylation of Foxm1 1 0.10 0.9 1.05
174 INT116529 Binding of HMOX1 10 0.47 15.38 1.04
175 INT130209 Positive_regulation of Phosphorylation of ATF2 3 0.36 1.15 1.03
176 INT164381 Regulation of Positive_regulation of MAPK3 2 0.60 1.49 1.03
177 INT9243 Gene_expression of FOXG1 14 0.53 7.52 1.02
178 INT214609 Positive_regulation of Gene_expression of FOXC1 1 0.08 1.78 1
179 INT46334 Binding of FOXC1 2 0.36 2.66 0.99
180 INT105445 Localization of HMOX1 5 0.71 3.11 0.98
181 INT43131 Regulation of FOXC1 3 0.36 1.09 0.98
182 INT151946 Positive_regulation of Regulation of Mapk3 1 0.16 1.31 0.96
183 INT281594 Phosphorylation of Foxo3 3 0.67 21.16 0.95
184 INT201454 Positive_regulation of Positive_regulation of Hmox1 6 0.35 5.2 0.94
185 INT148461 Positive_regulation of Transcription of Hmox1 6 0.33 1.83 0.93
186 INT194875 Regulation of Negative_regulation of MAPK14 1 0.04 2.39 0.91
187 INT69913 Binding of ATF2 6 0.13 0.83 0.84
188 INT72710 Negative_regulation of Negative_regulation of Foxm1 3 0.10 0.55 0.84
189 INT17330 Binding of FOXG1 3 0.33 0.23 0.83
190 INT95786 Positive_regulation of Positive_regulation of Mapk3 2 0.40 1.27 0.8
191 INT82568 Protein_catabolism of Hmox1 5 0.86 1.03 0.79
192 INT88179 Negative_regulation of Transcription of FOS 3 0.41 0.96 0.78
193 INT182293 Binding of MAPK8 11 0.34 4.6 0.77
194 INT194780 Regulation of Negative_regulation of MAPK1 3 0.32 3.42 0.76
195 INT167081 Binding of Mapk3 2 0.29 0.27 0.76
196 INT69922 Positive_regulation of ATF2 3 0.05 1.28 0.74
197 INT177940 Gene_expression of MAPK9 5 0.56 2.77 0.73
198 INT145932 Gene_expression of Hck 5 0.77 2.69 0.73
199 INT237709 Negative_regulation of Negative_regulation of MAPK8 6 0.25 2.09 0.72
200 INT226179 Phosphorylation of Foxo1 15 0.68 3.14 0.7
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