GO:0051091

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Name positive regulation of sequence-specific DNA binding transcription factor activity
Categary Process
Go Slim No
Go Link GO:0051091
Unique Molecular Interactions 4893
Total Molecular Interactions 7068
Total Single Events 54319
Pain Genes Associated 100

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of sequence-specific DNA binding transcription factor activity. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of sequence-specific DNA binding transcription factor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT69886 Ngf Positive_regulation of Calca 8 0.76 2.98 12.77
2 INT145775 Ngf Positive_regulation of Trpv1 11 0.72 7.71 11.25
3 INT77646 Binding of Ngf and Ntrk1 23 0.40 7.85 9.26
4 INT132225 Negative_regulation of Binding of Akt1 and Sh2d6 1 0.10 3.92 7.2
5 INT69229 Ngf Positive_regulation of Gene_expression of Bdnf 6 0.76 8.19 6.66
6 INT84921 Binding of NGF and NTRK1 13 0.50 6.39 6.1
7 INT122779 Ngf Positive_regulation of Gene_expression of Trpv1 8 0.74 4.31 6.1
8 INT179502 Binding of Cd14 and Tlr4 29 0.39 13.77 5.73
9 INT79759 Ngf Regulation of Il6 1 0.60 4.62 5.62
10 INT95068 Tlr4 Positive_regulation of IL1B 1 0.03 4.54 5.6
11 INT88279 Ngf Positive_regulation of Ntrk1 5 0.76 3.06 5.23
12 INT69888 Ngf Positive_regulation of Localization of Calca 4 0.52 0.51 4.95
13 INT139706 Tnf Positive_regulation of Ltp 1 0.03 2.61 4.63
14 INT128296 Negative_regulation of IL1B Positive_regulation of Insr 1 0.10 1.36 4.52
15 INT128295 IL1B Positive_regulation of Insr 1 0.11 1.36 4.5
16 INT64718 IL1B Positive_regulation of Gene_expression of IL6 15 0.59 9.37 4.48
17 INT240653 Ngf Positive_regulation of Positive_regulation of Bdnf 1 0.55 2.97 4.23
18 INT73539 Binding of Ngf and Ngfr 5 0.45 3.99 4
19 INT82023 Binding of Ntrk1 and Ngf 5 0.53 3.48 3.92
20 INT61359 TNF Positive_regulation of NFKB1 11 0.63 6.66 3.89
21 INT122349 Ngf Regulation of Trpv1 3 0.64 1.55 3.79
22 INT180813 Ngf Positive_regulation of Sorbs1 1 0.04 2.09 3.79
23 INT141254 Ngf Regulation of Transcription of Trpv1 1 0.53 1.37 3.74
24 INT85541 Ngf Positive_regulation of Gene_expression of Calca 2 0.55 1.84 3.71
25 INT132862 Ngf Positive_regulation of Bdnf 4 0.46 4.05 3.65
26 INT132231 Negative_regulation of Binding of Akt1 and Pik3cg 1 0.34 1.96 3.6
27 INT57985 Il1b Positive_regulation of Il6 5 0.59 1.66 3.53
28 INT74159 Ngf Regulation of Gene_expression of Calca 2 0.60 1.66 3.22
29 INT146412 Tnf Positive_regulation of Gene_expression of Trpv1 2 0.66 5.22 3.22
30 INT91271 Mtr Regulation of Gene_expression of Il6 1 0.20 0 3.17
31 INT64719 IL1B Positive_regulation of IL6 7 0.41 6.84 3.14
32 INT317522 Akt1 Positive_regulation of Phosphorylation of Nos1 1 0.43 0.4 3.13
33 INT171974 Binding of Tnfrsf11a and Tnfsf11 14 0.35 13.11 3.11
34 INT122780 Ngf Regulation of Gene_expression of Trpv1 4 0.65 3.74 3.11
35 INT150889 Il1a Regulation of Il10 1 0.22 3.49 2.95
36 INT150886 Il1a Regulation of Il1b 1 0.02 3.46 2.93
37 INT150888 Il1a Regulation of Il6 1 0.10 3.47 2.93
38 INT221746 Ngf Positive_regulation of Ntrk1 1 0.02 0.92 2.88
39 INT130721 Binding of IL1B and IL1RN 6 0.05 5.29 2.85
40 INT86180 SFTPA1 Positive_regulation of Localization of IL6 2 0.06 2.01 2.85
41 INT220062 Binding of NGF and TNFRSF1B 1 0.10 2.21 2.81
42 INT222522 Il1a Positive_regulation of Gene_expression of Il6 2 0.06 1.79 2.79
43 INT168758 Hist1h1t Positive_regulation of Phosphorylation of Akt1 2 0.02 0.44 2.79
44 INT317551 Binding of Akt1 and Oprm1 1 0.19 0.21 2.74
45 INT154187 Il6 Positive_regulation of Gene_expression of Cd2 1 0.08 3.07 2.71
46 INT154188 Il6 Positive_regulation of Gene_expression of Atf3 1 0.76 3.07 2.71
47 INT147107 TGFB1 Positive_regulation of Gene_expression of NGF 1 0.49 0.67 2.69
48 INT152113 Binding of NTSR1 and Ngf 3 0.33 2.09 2.62
49 INT140024 Tnf Positive_regulation of Gene_expression of Il1b 2 0.49 2.75 2.61
50 INT152501 Binding of Tnf and Tnfrsf1a 4 0.31 3 2.58
51 INT67905 Binding of Spn and Fosl1 1 0.24 2.1 2.54
52 INT151826 Tnf Positive_regulation of TNF 1 0.04 3.38 2.51
53 INT294909 Pax3 Positive_regulation of Gene_expression of Il6 1 0.09 5.43 2.51
54 INT170037 Ngf Regulation of Gene_expression of DRGX 1 0.01 1.37 2.46
55 INT103330 Ngf Positive_regulation of Gdnf 2 0.28 1.27 2.45
56 INT117532 SETBP1 Positive_regulation of Gene_expression of TNF 1 0.54 0.85 2.44
57 INT122163 Binding of TNF and TNFRSF1B 6 0.44 6.06 2.41
58 INT103332 Ngf Regulation of Gene_expression of TRPV1 3 0.09 2.6 2.4
59 INT115367 Binding of IL6 and IL6R 12 0.07 8.16 2.36
60 INT61733 Tlr4 Positive_regulation of Gene_expression of Tnf 3 0.26 1.99 2.36
61 INT121726 Ngf Positive_regulation of Phosphorylation of Akt1 1 0.37 1.4 2.34
62 INT108987 Ngf Regulation of Gene_expression of Sit1 1 0.00 1.46 2.32
63 INT314205 Ngf Positive_regulation of Phosphorylation of Mapk14 1 0.43 1.24 2.3
64 INT139705 Negative_regulation of Tnf Positive_regulation of Ltp 1 0.03 1.19 2.3
65 INT228454 Ngf Positive_regulation of Phosphorylation of Trpv1 1 0.39 2.97 2.26
66 INT124121 IL6 Positive_regulation of CCL2 1 0.26 1.84 2.25
67 INT126717 Binding of Il6 and Il6st 3 0.21 3.35 2.22
68 INT124120 IL6 Regulation of CCL2 1 0.15 1.8 2.22
69 INT114432 Oprl1 Positive_regulation of Akt1 1 0.18 0.08 2.2
70 INT279361 Binding of TNF and KLF1 4 0.00 3.72 2.19
71 INT69887 Ngf Regulation of Calca 2 0.49 0.1 2.19
72 INT94492 Il6 Positive_regulation of Gene_expression of Il1b 1 0.27 3.81 2.19
73 INT94491 Il1b Positive_regulation of Gene_expression of Tnf 1 0.25 3.81 2.19
74 INT94504 Il6 Positive_regulation of Gene_expression of Tnf 1 0.30 3.8 2.19
75 INT94494 Il1b Positive_regulation of Gene_expression of Il6 1 0.27 3.81 2.19
76 INT113451 Ngf Regulation of Gene_expression of ASIC3 1 0.07 1.35 2.18
77 INT12140 Ngf Regulation of Chat 1 0.44 1.67 2.18
78 INT86179 TNF Positive_regulation of Localization of IL6 5 0.35 1.66 2.17
79 INT209924 IL1B Negative_regulation of PPARA 1 0.20 4.38 2.17
80 INT212301 NGF Regulation of Gene_expression of TRPV1 1 0.23 2.37 2.13
81 INT351380 Ngf Regulation of TPM1 1 0.44 2.17 2.11
82 INT120319 Ghrh Regulation of Ngf 1 0.25 1.89 2.11
83 INT148704 Binding of TNF and TNFRSF1A 5 0.44 3.3 2.09
84 INT196586 Negative_regulation of Mapk14 Negative_regulation of TNF 2 0.04 2.02 2.08
85 INT113452 Ngf Positive_regulation of Gene_expression of ASIC3 1 0.19 1.34 2.08
86 INT126400 ITIH4 Positive_regulation of Gene_expression of Il6 1 0.00 2.11 2.08
87 INT70043 IL6 Regulation of IL10 3 0.18 3.59 2.01
88 INT140032 Tnf Positive_regulation of Gene_expression of Ifng 2 0.43 2.23 2
89 INT140030 Il1b Positive_regulation of Gene_expression of Ifng 2 0.48 2.23 2
90 INT140026 Il1b Positive_regulation of Gene_expression of Tnf 2 0.49 2.23 2
91 INT164784 Il6 Positive_regulation of Gene_expression of Cx3cr1 1 0.47 2.37 1.98
92 INT278937 LEP Positive_regulation of Gene_expression of IL6 1 0.32 3.42 1.97
93 INT217042 IRF6 Positive_regulation of TNF 4 0.27 3.03 1.95
94 INT129212 RYBP Positive_regulation of Tnf 2 0.03 1.9 1.95
95 INT156509 Il6 Regulation of Positive_regulation of Grin1 1 0.28 1.93 1.93
96 INT102130 Il6 Positive_regulation of Gene_expression of Crp 4 0.05 7.39 1.91
97 INT279359 Binding of ADA and TNF 1 0.20 2.61 1.91
98 INT93293 Ngf Regulation of Trpv1 2 0.28 0.71 1.9
99 INT166945 Ngf Positive_regulation of Trpv1 1 0.01 0.47 1.88
100 INT271408 NGF Positive_regulation of Gene_expression of CALCA 1 0.09 4.89 1.88
101 INT51051 IL1B Positive_regulation of Localization of IL6 7 0.57 3.79 1.87
102 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87
103 INT166947 Ngf Positive_regulation of KNG1 1 0.00 0.47 1.86
104 INT276668 Ngf Regulation of Nav1 1 0.09 0.98 1.85
105 INT81920 Binding of IL1B and NFKB1 1 0.04 1.54 1.85
106 INT185097 NGF Regulation of Gene_expression of NAV1 1 0.61 0.81 1.85
107 INT50993 Il1b Positive_regulation of Fos 2 0.40 0.43 1.84
108 INT314210 Ngf Regulation of Phosphorylation of Mapk14 1 0.34 0.85 1.84
109 INT163514 Ngf Positive_regulation of Gene_expression of Calca 1 0.30 2.21 1.82
110 INT199287 TNF Positive_regulation of Transcription of Oprm1 2 0.02 1.86 1.8
111 INT224432 TNF Positive_regulation of Gene_expression of VEGFA 1 0.13 5.83 1.8
112 INT132229 Binding of Akt1 and Sh2d6 1 0.09 0.98 1.8
113 INT136273 NGF Regulation of Gene_expression of BDNF 2 0.41 1.14 1.78
114 INT86997 Binding of HIVEP1 and NGF 2 0.03 1.75 1.73
115 INT137207 Tnf Positive_regulation of Nfkb1 3 0.23 2.69 1.71
116 INT169464 Akt1 Positive_regulation of Egfr 1 0.28 1.63 1.7
117 INT119413 SEMA6A Positive_regulation of TNFRSF11A 1 0.10 2.48 1.7
118 INT167427 Mapk8 Regulation of Regulation of Tnf 1 0.26 2.83 1.7
119 INT89379 TNF Positive_regulation of Gene_expression of IL6 5 0.50 4.37 1.69
120 INT215100 Binding of Hmgb1 and Tlr4 5 0.29 3.21 1.68
121 INT213071 IL6 Positive_regulation of Gene_expression of CRP 4 0.52 6.58 1.68
122 INT80199 Ngf Regulation of Transcription of Rab38 1 0.01 1.48 1.68
123 INT145098 NGF Positive_regulation of BDNF 1 0.66 1.33 1.67
124 INT108066 Binding of NTRK1 and Ngf 3 0.33 2.56 1.66
125 INT100274 IL1RN Negative_regulation of IL1B 5 0.53 1.79 1.65
126 INT83093 IL1B Positive_regulation of BDKRB1 1 0.51 0.44 1.65
127 INT322412 PPBP Negative_regulation of Phosphorylation of Akt1 1 0.01 0 1.65
128 INT61134 IL10 Negative_regulation of Gene_expression of IL1B 3 0.46 2.13 1.63
129 INT79778 Tlr4 Positive_regulation of Localization of TNF 4 0.08 4.21 1.61
130 INT167200 Gtf3a Regulation of Gene_expression of Ngf 1 0.08 1.47 1.6
131 INT266768 NGF Positive_regulation of Localization of SFTPA1 1 0.01 1.65 1.6
132 INT167202 TNF Regulation of Gene_expression of Ngf 1 0.10 1.47 1.6
133 INT209853 TNF Regulation of Gene_expression of CD36 1 0.61 3.41 1.59
134 INT140341 Ngf Positive_regulation of Gene_expression of Oprm1 1 0.02 0.33 1.59
135 INT266767 SFTPA1 Positive_regulation of Gene_expression of TNF 1 0.01 1.69 1.59
136 INT158774 Mapk14 Regulation of Il6 1 0.11 0.08 1.57
137 INT76651 Cpe Positive_regulation of Gene_expression of Il6 1 0.08 0 1.56
138 INT314214 Mapk14 Positive_regulation of Ngf 1 0.43 1.97 1.56
139 INT74937 IL1B Positive_regulation of CPOX 5 0.18 1.13 1.55
140 INT182097 Binding of Il6 and Il1 4 0.07 4.67 1.55
141 INT198653 TNF Positive_regulation of MIF 1 0.15 3.81 1.55
142 INT254205 Binding of Myd88 and Tlr4 12 0.19 3.17 1.54
143 INT252633 Binding of TNF and Tnfrsf1b 4 0.05 3.66 1.54
144 INT151849 IL10 Negative_regulation of Gene_expression of IL8 4 0.14 3.26 1.54
145 INT170654 Binding of Ntf3 and Ngf 1 0.38 1.66 1.54
146 INT91456 IL1B Positive_regulation of Gene_expression of CPOX 6 0.17 3.36 1.53
147 INT167201 Gtf3a Regulation of TNF 1 0.01 1.39 1.52
148 INT158775 Regulation of Tnf Regulation of Ephb1 1 0.18 0.09 1.52
149 INT135276 Gt(pU21)50Imeg Negative_regulation of Gene_expression of Il6 1 0.02 0.52 1.52
150 INT158777 Tnf Regulation of Ephb1 1 0.18 0.09 1.51
151 INT76656 POMC Positive_regulation of Gene_expression of Il6 1 0.03 0 1.51
152 INT10276 Il1b Regulation of Gene_expression of Penk 1 0.61 0.85 1.5
153 INT140029 Ifng Positive_regulation of Gene_expression of Tnf 1 0.43 1.69 1.5
154 INT140028 Ifng Positive_regulation of Gene_expression of Il1b 1 0.48 1.69 1.5
155 INT126718 Binding of Il6 and Il6r 3 0.09 2.33 1.49
156 INT190772 Il4 Negative_regulation of Gene_expression of Ptger2 1 0.03 1.28 1.49
157 INT159657 Binding of INSRR and NGF 3 0.00 1.65 1.48
158 INT220058 NGF Positive_regulation of Gene_expression of BDNF 1 0.12 1.31 1.48
159 INT220059 NGF Positive_regulation of Positive_regulation of BDNF 1 0.11 1.31 1.48
160 INT150885 Il6 Regulation of Il10 1 0.22 1.74 1.47
161 INT150887 Il1b Regulation of Il10 1 0.04 1.74 1.47
162 INT158776 Il1b Regulation of Ephb1 1 0.15 0.09 1.46
163 INT285569 TNF Negative_regulation of Gene_expression of Il6 1 0.03 2.83 1.46
164 INT72755 Tap1 Negative_regulation of TNF 1 0.43 2.45 1.46
165 INT190773 Il4 Negative_regulation of Gene_expression of Ptgs2 1 0.06 1.26 1.45
166 INT190774 Il4 Negative_regulation of Positive_regulation of Ptgs2 1 0.06 1.26 1.45
167 INT121226 Ngf Regulation of Gene_expression of Trpv1 2 0.62 0.7 1.44
168 INT155371 VIP Positive_regulation of Localization of IL6 1 0.64 3.37 1.44
169 INT180789 Ngf Regulation of Localization of Trpv1 1 0.28 1.22 1.44
170 INT266771 Binding of NGF and GOPC 1 0.05 3.23 1.43
171 INT214372 Ptprq Positive_regulation of Akt1 1 0.04 0.88 1.43
172 INT236365 Binding of CD40LG and IL6 3 0.20 4.16 1.42
173 INT131156 Binding of RUNX1 and TNF 2 0.03 3.44 1.42
174 INT214369 Pik3cb Positive_regulation of Akt1 1 0.56 0.87 1.41
175 INT180809 Ngf Positive_regulation of Positive_regulation of Sorbs1 1 0.03 0.84 1.4
176 INT190775 Gene_expression of Il4 Negative_regulation of Positive_regulation of FOSL1 1 0.39 2.42 1.4
177 INT180808 Ngf Positive_regulation of Gene_expression of Sorbs1 1 0.03 0.84 1.4
178 INT172834 Binding of IL6 and T2dm2 1 0.00 6.4 1.4
179 INT197111 Binding of IL1B and MCF2 1 0.02 2.12 1.4
180 INT220060 Negative_regulation of Binding of NGF and NTRK1 1 0.08 1.11 1.39
181 INT118980 NTRK1 Positive_regulation of NGF 1 0.56 1.45 1.39
182 INT223156 Il6 Regulation of A2m 1 0.11 2.79 1.39
183 INT82025 Negative_regulation of Binding of Ntrk1 and Ngf 1 0.47 0.64 1.37
184 INT218309 Binding of CRP and IL6 3 0.23 4.78 1.36
185 INT161511 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Il1b 1 0.41 0.27 1.36
186 INT177457 Il1 Positive_regulation of Gene_expression of Il6 3 0.16 4.47 1.35
187 INT60992 Ngf Regulation of CRTAC1 1 0.00 0 1.35
188 INT161513 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Tnf 1 0.33 0.27 1.35
189 INT151770 Binding of P2RX3 and Ngf 1 0.18 0.9 1.35
190 INT160586 IL6 Positive_regulation of Gene_expression of OPRM1 1 0.14 0.54 1.35
191 INT160588 TNF Positive_regulation of Gene_expression of OPRM1 1 0.20 0.54 1.35
192 INT160589 IL4 Positive_regulation of Gene_expression of OPRM1 1 0.13 0.54 1.35
193 INT250934 Binding of BDNF and NGF 3 0.39 0.62 1.34
194 INT140531 Ngf Positive_regulation of DYT10 1 0.72 1.83 1.34
195 INT60989 Ngf Regulation of Th 1 0.17 0 1.34
196 INT264327 IL-17 Positive_regulation of Gene_expression of Tnfsf11 1 0.07 3.19 1.33
197 INT56087 TNF Regulation of Gene_expression of SERPINE1 1 0.43 1.67 1.33
198 INT300864 Ngf Positive_regulation of Mapk14 2 0.60 1.38 1.32
199 INT180786 Calca Regulation of Positive_regulation of Ngf 1 0.40 0 1.32
200 INT136603 Calca Positive_regulation of Localization of Il6 1 0.67 0.78 1.32

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of sequence-specific DNA binding transcription factor activity. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of sequence-specific DNA binding transcription factor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82
2 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22
3 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98
4 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81
5 INT5680 Gene_expression of Ngf 530 0.78 264.29 310.56
6 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68
7 INT6852 Localization of TNF 883 0.81 705.95 270.84
8 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57
9 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97
10 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57
11 INT11377 Positive_regulation of Ngf 331 0.70 206.5 238
12 INT6481 Binding of TNF 624 0.48 510.2 214.82
13 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210
14 INT11313 Positive_regulation of Il6 526 0.70 331.27 201.59
15 INT6488 Gene_expression of Tnf 484 0.78 339.61 191.58
16 INT24326 Gene_expression of Ngf 346 0.78 218.67 184.71
17 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38
18 INT13353 Positive_regulation of Tnf 332 0.70 248.75 148.1
19 INT60694 Gene_expression of Il10 567 0.78 369.48 143.69
20 INT9660 Regulation of TNF 363 0.62 312.94 139.99
21 INT48895 Gene_expression of Il10 333 0.78 221.2 138.52
22 INT7533 Gene_expression of Tlr4 720 0.78 343.22 121.57
23 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28
24 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61
25 INT20374 Gene_expression of Il4 515 0.76 306.15 114.12
26 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3
27 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84
28 INT12082 Localization of IL6 365 0.81 241.78 105.78
29 INT10272 Gene_expression of Il1b 194 0.78 121.02 103.03
30 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9
31 INT10166 Localization of Tnf 237 0.81 153.95 88.64
32 INT21793 Positive_regulation of Ngf 154 0.70 94.78 85.27
33 INT16254 Positive_regulation of Gene_expression of Ngf 144 0.70 80.61 82.08
34 INT17546 Negative_regulation of Ngf 135 0.59 60.28 77.19
35 INT62374 Gene_expression of NGF 158 0.78 77.87 76.45
36 INT12001 Regulation of Ngf 97 0.62 54.64 76.25
37 INT15769 Gene_expression of Il1b 146 0.78 114.51 75.35
38 INT10274 Positive_regulation of Il1b 123 0.70 79.76 73.56
39 INT48244 Gene_expression of Il4 172 0.76 132.38 73.42
40 INT9236 Regulation of Gene_expression of TNF 204 0.62 162.66 72.99
41 INT56298 Gene_expression of IL4 306 0.78 182.18 72.92
42 INT3034 Localization of Ngf 126 0.81 50.81 72.84
43 INT11380 Negative_regulation of IL1B 215 0.59 125.62 72.35
44 INT58400 Negative_regulation of Tnf 182 0.59 129.97 71
45 INT49995 Positive_regulation of Gene_expression of Tnf 187 0.70 125.07 70.54
46 INT6849 Localization of IL1B 229 0.81 112.56 69.63
47 INT6489 Positive_regulation of Gene_expression of Tnf 140 0.70 92.31 67.85
48 INT19511 Localization of Il6 212 0.81 118.17 67.67
49 INT6486 Positive_regulation of Tnf 168 0.70 123.47 66.05
50 INT11937 Localization of Il6 228 0.81 139.83 64.39
51 INT9657 Positive_regulation of Gene_expression of Il6 237 0.70 180.45 63.6
52 INT1951 Positive_regulation of Tlr4 345 0.70 176.99 62.42
53 INT10706 Regulation of Il6 150 0.62 93.23 62.34
54 INT103924 Positive_regulation of Akt1 359 0.69 158.94 60.34
55 INT48901 Negative_regulation of IL6 186 0.57 136.33 57.87
56 INT48891 Positive_regulation of Il10 143 0.70 101.42 56.72
57 INT52800 Negative_regulation of Gene_expression of Tnf 142 0.59 92.27 55.47
58 INT63975 Positive_regulation of Il10 175 0.68 134.13 54.69
59 INT117713 Phosphorylation of Akt1 275 0.82 95.82 54.34
60 INT49993 Positive_regulation of Gene_expression of Il6 149 0.70 88.07 53.78
61 INT9234 Negative_regulation of Gene_expression of IL6 171 0.59 101.61 53.15
62 INT22112 Positive_regulation of Localization of TNF 164 0.70 115.66 52.18
63 INT27954 Positive_regulation of Gene_expression of Ngf 87 0.70 57.91 51.96
64 INT6473 Positive_regulation of Gene_expression of IL1B 204 0.70 117.23 50.86
65 INT9210 Regulation of IL6 166 0.62 125.61 49.95
66 INT40777 Positive_regulation of Akt1 163 0.69 59.41 49.43
67 INT66029 Negative_regulation of Tnf 100 0.59 84.28 48.16
68 INT106525 Phosphorylation of Akt1 436 0.82 183.81 47.82
69 INT55670 Negative_regulation of Gene_expression of Tnf 83 0.59 57.16 46.33
70 INT19078 Binding of Ngf 78 0.48 31.03 44.33
71 INT73502 Positive_regulation of IL10 154 0.69 124.87 43.5
72 INT5307 Regulation of Tnf 87 0.62 78.71 43.4
73 INT60695 Positive_regulation of Gene_expression of Il10 154 0.70 120.28 43.07
74 INT50957 Negative_regulation of Il6 134 0.59 79.08 42.67
75 INT13354 Transcription of TNF 108 0.72 85.81 42.32
76 INT9233 Negative_regulation of Gene_expression of IL1B 114 0.59 56.99 41.82
77 INT11939 Negative_regulation of Il6 138 0.59 87.46 41.24
78 INT48075 Positive_regulation of Il1b 71 0.67 48.63 40.48
79 INT5973 Regulation of IL1B 109 0.62 66.6 39.88
80 INT20210 Localization of Ngf 69 0.79 46.22 38.57
81 INT9239 Regulation of Gene_expression of IL6 106 0.61 75.24 36.53
82 INT48896 Positive_regulation of Gene_expression of Il10 73 0.70 43.14 35.5
83 INT53577 Negative_regulation of Localization of TNF 110 0.59 59.28 35.23
84 INT6484 Binding of IL1B 122 0.47 75.84 35.07
85 INT20380 Gene_expression of Il5 172 0.78 104.75 34.78
86 INT67613 Positive_regulation of PPARG 94 0.70 69.15 34.38
87 INT81289 Positive_regulation of Gene_expression of Tlr4 192 0.69 104.5 33.89
88 INT93534 Gene_expression of Tnfsf11 185 0.77 119.26 33.66
89 INT9658 Negative_regulation of Gene_expression of Il6 110 0.59 66.29 32.58
90 INT9655 Regulation of Il6 98 0.62 70.92 31.95
91 INT114881 Gene_expression of Akt1 227 0.78 102.49 31.81
92 INT35406 Localization of Tnf 94 0.81 64.63 31.65
93 INT9347 Localization of Il1b 58 0.81 26.13 31.53
94 INT13186 Positive_regulation of Il4 113 0.68 71.22 31.4
95 INT56809 Binding of Tlr4 184 0.48 106.02 31.18
96 INT8027 Regulation of Gene_expression of Ngf 34 0.62 26.32 31.16
97 INT56290 Negative_regulation of Gene_expression of Il6 79 0.59 47.98 31.07
98 INT54302 Positive_regulation of Gene_expression of Il4 126 0.68 86.18 30.75
99 INT23435 Positive_regulation of NGF 54 0.70 32.41 30.11
100 INT90792 Localization of Il10 144 0.80 87.88 30.03
101 INT50230 Positive_regulation of Localization of IL6 105 0.70 69.21 29.52
102 INT86437 Binding of IL6 154 0.48 121.22 29.3
103 INT57692 Positive_regulation of Gene_expression of Il1b 50 0.67 43.54 28.29
104 INT118734 Gene_expression of Tlr4 70 0.78 55.7 28.19
105 INT112707 Negative_regulation of Akt1 89 0.59 28.85 27.76
106 INT69157 Gene_expression of IL5 127 0.77 102.58 26.81
107 INT52801 Regulation of Gene_expression of Tnf 55 0.62 48.74 26.59
108 INT10273 Positive_regulation of Gene_expression of Il1b 47 0.68 31.15 26.21
109 INT63769 Regulation of Ngf 44 0.62 21.82 25.84
110 INT70048 Positive_regulation of Gene_expression of IL10 90 0.55 71.34 25.66
111 INT122570 Negative_regulation of Akt1 173 0.59 91.44 25.53
112 INT5948 Regulation of Il1b 44 0.60 22.8 25.4
113 INT67610 Positive_regulation of Pparg 53 0.70 31.91 25.2
114 INT5199 Gene_expression of Fosl1 44 0.78 8.66 24.8
115 INT64185 Gene_expression of TNFRSF11A 131 0.76 75.15 24.73
116 INT48240 Binding of Ngf 46 0.46 23.51 24.42
117 INT40776 Gene_expression of Akt1 99 0.77 34.91 24.39
118 INT10349 Negative_regulation of Il1b 48 0.58 25.53 24.24
119 INT117718 Positive_regulation of Phosphorylation of Akt1 112 0.69 39.26 24.09
120 INT51029 Negative_regulation of Il1b 34 0.57 29.34 23.62
121 INT50039 Positive_regulation of Il4 48 0.55 34.8 23.34
122 INT74423 Localization of IL10 91 0.80 61.6 22.95
123 INT91891 Gene_expression of Kit 268 0.78 158.89 22.67
124 INT48081 Localization of Il1b 46 0.80 21.59 22.4
125 INT62373 Negative_regulation of NGF 34 0.59 25.87 22.38
126 INT66753 Negative_regulation of Positive_regulation of Tnf 45 0.59 35.28 22.33
127 INT8483 Positive_regulation of Positive_regulation of TNF 73 0.67 60.35 22.03
128 INT78057 Localization of Tlr4 140 0.77 67.75 21.72
129 INT73625 Gene_expression of PPARG 108 0.78 104.85 21.42
130 INT7535 Negative_regulation of Tlr4 111 0.56 56.84 21.37
131 INT30887 Negative_regulation of Ngf 56 0.59 32.96 20.86
132 INT53575 Regulation of Gene_expression of Tnf 46 0.62 34.35 20.63
133 INT20379 Localization of Il4 85 0.73 51.22 20.55
134 INT51474 Binding of Il6 55 0.48 44.99 20.52
135 INT86751 Negative_regulation of Il10 62 0.59 40.1 20.51
136 INT62042 Positive_regulation of Gene_expression of IL4 67 0.56 42.05 20.39
137 INT9237 Regulation of Gene_expression of IL1B 49 0.62 30.69 20.34
138 INT49985 Transcription of Il6 62 0.72 40.13 20.29
139 INT65907 Negative_regulation of Gene_expression of Ngf 36 0.59 19.5 20.03
140 INT69304 Negative_regulation of Il10 47 0.59 36.88 19.79
141 INT64261 Negative_regulation of Positive_regulation of Ngf 21 0.59 16.28 19.78
142 INT53574 Regulation of Tnf 45 0.62 40.68 19.71
143 INT89396 Phosphorylation of AKT1 225 0.82 111.66 19.61
144 INT67608 Gene_expression of Pparg 41 0.78 25.09 19.53
145 INT86187 Positive_regulation of AKT1 199 0.69 122.13 19.44
146 INT74286 Regulation of Il10 42 0.44 28.06 19.44
147 INT66751 Negative_regulation of Localization of Tnf 48 0.59 26 19.36
148 INT66755 Transcription of Tnf 45 0.72 37.1 19.11
149 INT51054 Negative_regulation of Localization of IL6 45 0.59 24.48 18.97
150 INT56301 Positive_regulation of IL4 68 0.56 54.51 18.65
151 INT11938 Positive_regulation of Localization of Il6 61 0.70 35.72 18.25
152 INT61626 Transcription of IL6 73 0.72 42.04 17.86
153 INT9656 Regulation of Gene_expression of Il6 57 0.62 33.3 17.71
154 INT49922 Positive_regulation of Positive_regulation of Ngf 21 0.67 14.46 17.68
155 INT72564 Localization of Il10 41 0.78 28.62 17.6
156 INT36054 Transcription of IL1B 53 0.72 32.64 17.31
157 INT15358 Transcription of Ngf 29 0.72 10.43 16.94
158 INT48892 Transcription of Il10 31 0.71 27.26 16.77
159 INT10169 Positive_regulation of Localization of Tnf 44 0.70 27.71 16.75
160 INT20216 Localization of NGF 40 0.80 18.16 16.61
161 INT19929 Negative_regulation of Positive_regulation of TNF 52 0.59 38.16 16.51
162 INT84924 Positive_regulation of Gene_expression of NGF 29 0.68 17.91 16.46
163 INT48238 Regulation of Gene_expression of Ngf 25 0.62 11.48 16.42
164 INT49986 Transcription of Tnf 25 0.72 18.3 16.22
165 INT50932 Positive_regulation of Positive_regulation of Il6 36 0.69 24.9 16.12
166 INT97245 Gene_expression of AKT1 217 0.77 119.63 15.59
167 INT43906 Regulation of Tlr4 71 0.53 35.18 15.49
168 INT12087 Regulation of Localization of TNF 44 0.62 28.71 15.17
169 INT49532 Regulation of Gene_expression of Il6 43 0.61 25.8 14.99
170 INT49376 Negative_regulation of Localization of Il6 37 0.59 12.66 14.99
171 INT71150 Binding of NGF 22 0.46 13.67 14.81
172 INT69303 Positive_regulation of Gene_expression of Il4 27 0.68 20.01 14.8
173 INT67641 Negative_regulation of Gene_expression of Tlr4 90 0.58 46 14.6
174 INT151120 Negative_regulation of Tlr4 18 0.59 21.09 14.46
175 INT25266 Positive_regulation of Localization of IL1B 38 0.69 15.89 14.35
176 INT10173 Binding of Tnf 45 0.48 35.6 14.32
177 INT64048 Positive_regulation of Positive_regulation of Tnf 32 0.70 21.24 13.74
178 INT29170 Negative_regulation of Gene_expression of Il1b 25 0.59 16.36 13.68
179 INT55256 Negative_regulation of Localization of Il6 38 0.58 16.12 13.67
180 INT19191 Negative_regulation of Localization of IL1B 35 0.58 15.19 13.63
181 INT109304 Positive_regulation of Phosphorylation of Akt1 113 0.69 40.92 13.49
182 INT6478 Negative_regulation of Binding of TNF 36 0.58 30.42 13.31
183 INT67611 Positive_regulation of Pparg 39 0.69 18.33 13.23
184 INT87235 Negative_regulation of Il4 54 0.48 31.51 13.15
185 INT54763 Binding of Il6 82 0.48 63.27 12.89
186 INT55255 Positive_regulation of Localization of Il6 48 0.69 24.88 12.76
187 INT86950 Negative_regulation of Gene_expression of Il10 26 0.42 18.92 12.73
188 INT89404 Regulation of Negative_regulation of TNF 30 0.45 24.47 12.71
189 INT58226 Negative_regulation of Gene_expression of Il1b 24 0.57 18.09 12.68
190 INT89395 Negative_regulation of AKT1 127 0.58 70.27 12.54
191 INT51028 Regulation of Il1b 28 0.60 21.15 12.47
192 INT70050 Negative_regulation of IL10 56 0.58 37.45 12.39
193 INT12084 Regulation of Localization of IL6 36 0.61 20.32 12.34
194 INT13409 Gene_expression of NEUROD1 52 0.75 14.17 12.23
195 INT69158 Localization of IL4 48 0.71 31.3 11.98
196 INT26534 Regulation of Akt1 34 0.61 14.47 11.86
197 INT50933 Transcription of Il6 38 0.72 24.31 11.58
198 INT55886 Negative_regulation of Gene_expression of Il4 47 0.57 26.04 11.42
199 INT7903 Positive_regulation of Fosl1 21 0.70 3.53 11.36
200 INT49396 Negative_regulation of Positive_regulation of Il6 29 0.59 16.39 11.31
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