GO:0051131

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Name chaperone-mediated protein complex assembly
Categary Process
Go Slim No
Go Link GO:0051131
Unique Molecular Interactions 50
Total Molecular Interactions 62
Total Single Events 451
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for chaperone-mediated protein complex assembly. They are ordered first by their pain relevance and then by number of times they were reported for chaperone-mediated protein complex assembly. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT258798 Binding of NR3C1 and HSP90AA1 1 0.01 1.09 0.78
2 INT27871 Binding of FCGR1B and HSPD1 1 0.01 1.93 0.56
3 INT27872 Positive_regulation of Binding of FCGR1B and HSPD1 1 0.01 1.93 0.56
4 INT299766 APCS Positive_regulation of Gene_expression of Cd80 1 0.04 0.86 0.5
5 INT299767 APCS Positive_regulation of Gene_expression of Cd86 1 0.07 0.86 0.5
6 INT299764 APCS Positive_regulation of Cd86 1 0.02 0.86 0.5
7 INT299765 APCS Positive_regulation of Cd80 1 0.04 0.85 0.49
8 INT85037 Binding of Cct2 and Chrna3 1 0.00 0.15 0.38
9 INT188521 Binding of Hsp90aa1 and Ptges3 1 0.02 0.61 0.33
10 INT111909 Binding of HSPD1 and CCT4 1 0.29 0.48 0.25
11 INT126227 Hsp90aa1 Positive_regulation of Nos1 1 0.03 0.73 0.25
12 INT111908 Binding of HSPD1 and AP4B1 1 0.03 0.48 0.25
13 INT289955 Binding of APCS and KLF1 1 0.00 0.21 0.23
14 INT324822 Binding of Cd24a and Hsp90aa1 1 0.10 0.71 0.19
15 INT231763 Binding of HSPD1 and TLR2 1 0.12 2 0.19
16 INT251492 Binding of HSPD1 and SOD1 1 0.02 1.45 0.18
17 INT231765 Binding of HSPD1 and TLR4 1 0.13 1.94 0.16
18 INT192358 CRP Regulation of Positive_regulation of HSPD1 1 0.15 2.46 0.1
19 INT192352 CRP Regulation of HSPD1 1 0.15 2.46 0.1
20 INT230857 Negative_regulation of Binding of HSP90AA1 and NOS1 1 0.05 1.18 0.09
21 INT230856 Binding of HSP90AA1 and NOS1 1 0.04 1.17 0.09
22 INT289957 Binding of APCS and CD58 1 0.04 0.35 0.08
23 INT293494 Sfpi1 Regulation of Negative_regulation of Hsp90aa1 1 0.04 0.23 0.05
24 INT329015 Binding of APCS and SRGN 1 0.08 1.14 0.04
25 INT334107 Binding of APC and APCS 1 0.16 1.52 0.04
26 INT350434 Negative_regulation of HSP90AA1 Positive_regulation of Gene_expression of ATF3 1 0.32 2.44 0.04
27 INT234196 ERBB2 Positive_regulation of Negative_regulation of HSP90AA1 1 0.19 0.79 0.03
28 INT299368 Mkks Positive_regulation of Mapk8 1 0.41 0.17 0.03
29 INT234195 HSP90AA1 Regulation of AKT1 1 0.14 0.65 0.03
30 INT192354 Binding of CRP and HSPD1 1 0.12 1.28 0
31 INT350432 HSP90AA1 Positive_regulation of Gene_expression of ATF3 1 0.32 1.27 0
32 INT292679 GOPC Positive_regulation of HSP90AA1 1 0.01 0.1 0
33 INT293492 Hsp90aa1 Regulation of Gene_expression of Sfpi1 1 0.04 0.1 0
34 INT340914 Binding of Hsp90aa1 and Fkbp6 1 0.12 0.26 0
35 INT350430 Negative_regulation of HSP90AA1 Positive_regulation of ATF3 1 0.32 3.11 0
36 INT293493 Hsp90aa1 Regulation of Gene_expression of Erbb2 1 0.38 0.1 0
37 INT234214 Binding of HSP90AA1 and Tpt1 1 0.04 0.42 0
38 INT256701 Binding of Hsp90aa1 and Hsp90b1 1 0.12 0.34 0
39 INT282743 Hsp90aa1 Positive_regulation of Kit 1 0.22 0.54 0
40 INT340913 Fkbp6 Negative_regulation of Binding of Hsp90aa1 1 0.14 0.26 0
41 INT317307 Binding of Hsp90aa1 and Pink1 1 0.12 0.56 0
42 INT350503 Binding of HSP90AA1 and JAK2 1 0.06 1.39 0
43 INT100265 Hsp90aa1 Regulation of Positive_regulation of Esrrb 1 0.10 0.1 0
44 INT340915 Binding of Hsp90aa1 and Ptplad1 1 0.12 0.17 0
45 INT265383 Hsp90aa1 Negative_regulation of HDAC9 1 0.06 0.7 0
46 INT277808 Binding of APCS and CD80 1 0.11 0.07 0
47 INT311064 HSP90AA1 Positive_regulation of Positive_regulation of HSF1 1 0.20 0.17 0
48 INT350431 HSP90AA1 Positive_regulation of ATF3 1 0.47 1.55 0
49 INT311061 HSP90AA1 Positive_regulation of HSF1 1 0.20 0.17 0
50 INT350505 Negative_regulation of Binding of HSP90AA1 and JAK2 1 0.07 1.5 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for chaperone-mediated protein complex assembly. They are ordered first by their pain relevance and then by number of times they were reported in chaperone-mediated protein complex assembly. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT111335 Gene_expression of HSPD1 57 0.75 55.51 10.38
2 INT37168 Positive_regulation of APCS 22 0.67 9.61 4.59
3 INT68675 Regulation of APCS 10 0.62 7.61 3.01
4 INT102729 Gene_expression of APCS 20 0.65 8.86 2.52
5 INT18853 Negative_regulation of APCS 13 0.57 4.51 2.3
6 INT27880 Positive_regulation of HSPD1 17 0.65 18.16 2.23
7 INT152436 Positive_regulation of Gene_expression of HSPD1 12 0.67 10.06 2.16
8 INT77656 Gene_expression of Hsp90aa1 12 0.78 24.27 1.81
9 INT27881 Binding of HSPD1 10 0.31 9.2 1.78
10 INT125320 Negative_regulation of HSP90AA1 20 0.45 23.93 1.42
11 INT88855 Negative_regulation of Hsp90aa1 4 0.54 2.16 1.34
12 INT112891 Regulation of Gene_expression of HSPD1 2 0.43 3.98 1.17
13 INT133898 Binding of HSP90AA1 17 0.30 8.83 1.12
14 INT100612 Positive_regulation of Hsp90aa1 4 0.64 5.3 1.01
15 INT215363 Regulation of HSPD1 4 0.51 2.74 0.99
16 INT37170 Binding of APCS 6 0.36 4.79 0.97
17 INT88861 Positive_regulation of Gene_expression of Hsp90aa1 4 0.64 7.43 0.9
18 INT90203 Negative_regulation of Cct2 2 0.35 0.34 0.65
19 INT192235 Binding of Hsp90aa1 6 0.19 1.46 0.6
20 INT88859 Transcription of Hsp90aa1 1 0.58 1.51 0.6
21 INT166086 Binding of Hsp90aa1 1 0.28 0.08 0.6
22 INT88857 Negative_regulation of Transcription of Hsp90aa1 1 0.36 1.52 0.6
23 INT165846 Regulation of HSP90AA1 4 0.27 2.19 0.58
24 INT37169 Positive_regulation of Binding of APCS 2 0.45 2.4 0.57
25 INT127480 Negative_regulation of Hsp90aa1 20 0.57 10.67 0.56
26 INT73976 Gene_expression of Hsp90aa1 18 0.75 7.92 0.45
27 INT88856 Negative_regulation of Gene_expression of Hsp90aa1 2 0.39 2.31 0.45
28 INT306291 Localization of HSPD1 1 0.31 0.81 0.36
29 INT170282 Negative_regulation of Gene_expression of APCS 2 0.11 0.6 0.34
30 INT293480 Protein_catabolism of Hsp90aa1 2 0.65 0.82 0.32
31 INT77654 Regulation of Gene_expression of Hsp90aa1 4 0.62 2.41 0.28
32 INT321641 Negative_regulation of Binding of APCS 1 0.23 2.26 0.26
33 INT321170 Positive_regulation of Protein_catabolism of Hsp90aa1 1 0.29 0.2 0.25
34 INT304603 Positive_regulation of HSP90AA1 1 0.26 7.01 0.24
35 INT166356 Negative_regulation of HSPD1 4 0.55 3 0.23
36 INT73178 Positive_regulation of Hsp90aa1 4 0.45 0.7 0.21
37 INT235538 Positive_regulation of Binding of HSPD1 1 0.08 1.15 0.19
38 INT163230 Gene_expression of Mkks 1 0.48 0.09 0.13
39 INT102355 Gene_expression of HSP90AA1 8 0.51 5.2 0.12
40 INT192360 Positive_regulation of Positive_regulation of HSPD1 1 0.29 0.77 0.11
41 INT243715 Gene_expression of Cct2 2 0.27 1.2 0.1
42 INT215368 Regulation of Positive_regulation of HSPD1 1 0.38 0.51 0.09
43 INT192236 Positive_regulation of Binding of Hsp90aa1 2 0.24 0.59 0.08
44 INT321640 Protein_catabolism of APCS 1 0.55 0.24 0.08
45 INT170283 Localization of APCS 2 0.29 0.73 0.07
46 INT234206 Localization of HSP90AA1 4 0.68 2.89 0.06
47 INT234211 Regulation of Negative_regulation of HSP90AA1 2 0.27 1.13 0.06
48 INT234207 Negative_regulation of Binding of HSP90AA1 2 0.26 0.84 0.05
49 INT302546 Regulation of Gene_expression of Hsp90aa1 1 0.21 0.88 0.04
50 INT328544 Localization of Hsp90aa1 1 0.10 0.17 0.03
51 INT234208 Negative_regulation of Localization of HSP90AA1 1 0.26 0.59 0.03
52 INT222086 Positive_regulation of Gene_expression of Hsp90aa1 1 0.24 0 0.03
53 INT234209 Protein_catabolism of HSP90AA1 5 0.54 2.67 0
54 INT234212 Positive_regulation of Gene_expression of HSP90AA1 3 0.41 1.36 0
55 INT73983 Transcription of Hsp90aa1 2 0.43 0.08 0
56 INT234213 Regulation of Binding of HSP90AA1 1 0.27 0.21 0
57 INT350514 Positive_regulation of Phosphorylation of HSP90AA1 1 0.10 0.74 0
58 INT222091 Regulation of Transcription of Hsp90aa1 1 0.09 0 0
59 INT311072 Positive_regulation of Localization of HSP90AA1 1 0.22 0.53 0
60 INT293485 Regulation of Hsp90aa1 1 0.33 0.37 0
61 INT350518 Phosphorylation of HSP90AA1 1 0.16 0.72 0
62 INT293483 Positive_regulation of Regulation of Hsp90aa1 1 0.37 0.37 0
63 INT152878 Positive_regulation of Positive_regulation of APCS 1 0.61 0 0
64 INT293488 Positive_regulation of Negative_regulation of Hsp90aa1 1 0.37 0.21 0
65 INT234205 Negative_regulation of Negative_regulation of HSP90AA1 1 0.26 0.28 0
66 INT293486 Negative_regulation of Protein_catabolism of Hsp90aa1 1 0.31 0.41 0
67 INT350445 Positive_regulation of Negative_regulation of HSP90AA1 1 0.30 3.25 0
68 INT293490 Negative_regulation of Gene_expression of Hsp90aa1 1 0.31 0.15 0
69 INT222079 Positive_regulation of Transcription of Hsp90aa1 1 0.16 0 0
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