GO:0051149

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Name positive regulation of muscle cell differentiation
Categary Process
Go Slim No
Go Link GO:0051149
Unique Molecular Interactions 85
Total Molecular Interactions 98
Total Single Events 740
Pain Genes Associated 12

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of muscle cell differentiation. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of muscle cell differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT264950 Binding of FPR1 and BOC 1 0.11 0.67 1.55
2 INT139724 PROC Positive_regulation of MAPK14 1 0.00 1.57 1.25
3 INT330379 Gene_expression of IL10 Negative_regulation of Positive_regulation of MAPK14 1 0.00 1.95 1.18
4 INT264944 Binding of POMC and BOC 1 0.07 0.44 0.89
5 INT209928 IL1B Positive_regulation of MAPK14 2 0.15 1.69 0.87
6 INT346234 MAP2K6 Positive_regulation of MAPK14 1 0.44 1.65 0.77
7 INT12238 CCK Positive_regulation of CDH2 1 0.02 0 0.7
8 INT264943 Negative_regulation of Binding of FPR1 and BOC 1 0.13 0.22 0.64
9 INT264952 Binding of GOPC and BOC 1 0.05 0.22 0.64
10 INT278694 TNF Positive_regulation of MAPK14 1 0.03 0.79 0.56
11 INT171906 MAPK1 Positive_regulation of Gene_expression of MAPK14 1 0.08 1.55 0.52
12 INT97949 Negative_regulation of NRP2 Negative_regulation of Positive_regulation of CDC42 1 0.06 0.72 0.51
13 INT97953 ST3GAL3 Positive_regulation of CDC42 1 0.09 0.7 0.5
14 INT264948 BOC Negative_regulation of FPR1 1 0.13 0.18 0.48
15 INT264949 BOC Negative_regulation of Localization of FPR1 1 0.13 0.18 0.48
16 INT264975 BOC Negative_regulation of Localization of Oprd1 1 0.01 0.17 0.48
17 INT346237 MAP2K6 Positive_regulation of MAP2K3 1 0.49 1 0.44
18 INT278964 MAPK14 Negative_regulation of Localization of EPHB2 1 0.15 0.47 0.43
19 INT278970 MAPK14 Positive_regulation of Gene_expression of IL8 1 0.11 0.66 0.37
20 INT278938 MAPK14 Positive_regulation of Gene_expression of PRKCA 1 0.05 0.65 0.37
21 INT278966 MAPK14 Positive_regulation of Gene_expression of LEP 1 0.16 0.62 0.36
22 INT346228 MAP2K6 Positive_regulation of Positive_regulation of MAPK14 1 0.44 0.68 0.34
23 INT346229 PREP Positive_regulation of MAPK14 1 0.13 0.63 0.34
24 INT346236 Binding of MAPK14 and MAP2K6 1 0.32 0.65 0.33
25 INT346231 Binding of MAPK14 and MAP2K3 1 0.33 0.65 0.33
26 INT297972 MAPK14 Negative_regulation of ING5 1 0.21 1.67 0.33
27 INT255944 MAPK14 Positive_regulation of Tauph 1 0.00 0.1 0.32
28 INT259639 MAPK14 Regulation of Gene_expression of IL8 1 0.02 1.2 0.32
29 INT255945 MAPK14 Positive_regulation of Rps6ka5 1 0.06 0.1 0.32
30 INT255946 MAPK14 Positive_regulation of Map3k1 1 0.04 0.1 0.32
31 INT346235 IL1B Positive_regulation of Gene_expression of MAPK14 1 0.15 0.64 0.32
32 INT112799 Positive_regulation of CASP1 Positive_regulation of MAPK14 1 0.02 0.16 0.3
33 INT123663 F2R Positive_regulation of MAPK14 1 0.12 0.42 0.26
34 INT123662 Negative_regulation of F2R Positive_regulation of MAPK14 1 0.08 0.42 0.26
35 INT171907 MAPK8 Positive_regulation of Gene_expression of MAPK14 1 0.06 0.77 0.26
36 INT123661 COL7A1 Positive_regulation of MAPK14 1 0.08 0.42 0.26
37 INT171911 MAPK8IP3 Positive_regulation of Gene_expression of MAPK14 1 0.05 0.77 0.26
38 INT179230 Binding of MAPK14 and GSR 1 0.03 0.5 0.23
39 INT292565 MAP3K5 Positive_regulation of Positive_regulation of CDC42 1 0.02 0 0.23
40 INT112794 CASP1 Positive_regulation of MAPK14 1 0.02 0.16 0.23
41 INT112793 IL4I1 Positive_regulation of Positive_regulation of MAPK14 1 0.04 0 0.22
42 INT341778 DBT Positive_regulation of MAP2K6 1 0.00 0 0.21
43 INT297965 MAPK14 Negative_regulation of GADD45A 1 0.05 1 0.21
44 INT274578 Binding of ABL1 and PSTPIP1 1 0.07 1.55 0.21
45 INT257218 Camk1 Negative_regulation of Nos1 1 0.04 0.09 0.19
46 INT226518 Il1rl1 Positive_regulation of MAPK14 1 0.04 0.2 0.15
47 INT246365 CALM1 Regulation of MAP2K6 1 0.00 0.34 0.15
48 INT226520 Il1rl1 Positive_regulation of Gene_expression of MAPK14 1 0.03 0.2 0.15
49 INT2230 SERPINB1 Positive_regulation of Localization of CDON 1 0.00 0 0.14
50 INT295480 MAPK14 Positive_regulation of Localization of TNF 1 0.08 1.08 0.12
51 INT297967 MAPK14 Negative_regulation of SCUBE3 1 0.01 0.67 0.12
52 INT291260 Map3k8 Regulation of Gene_expression of MAPK14 1 0.07 0.52 0.11
53 INT274583 Binding of ABL1 and PSTPIP2 1 0.06 0.79 0.11
54 INT287267 EGF Positive_regulation of CDC42 1 0.12 0.16 0.11
55 INT182268 Negative_regulation of MAPK14 Negative_regulation of Gene_expression of EDN1 1 0.22 0.31 0.07
56 INT182274 MAPK14 Negative_regulation of Gene_expression of EDN1 1 0.22 0.31 0.07
57 INT140289 ROS1 Positive_regulation of MAPK14 1 0.44 1.27 0.06
58 INT164128 TNFSF10 Positive_regulation of MAPK14 1 0.28 2.09 0.05
59 INT182264 EDN1 Positive_regulation of Positive_regulation of MAPK14 1 0.26 0.1 0.05
60 INT194727 MAP3K4 Positive_regulation of MAP2K6 1 0.06 0 0.04
61 INT194703 MAP2K1 Positive_regulation of MAP2K6 1 0.21 0 0.04
62 INT237682 LDHA Positive_regulation of MAPK14 1 0.02 0.16 0.03
63 INT209927 MAPK14 Positive_regulation of IL1B 1 0.13 0.05 0.03
64 INT298002 Gene_expression of Gadd45b Positive_regulation of MAPK14 1 0.29 0.67 0.03
65 INT297962 MAP3K4 Positive_regulation of MAPK14 1 0.21 0.66 0.03
66 INT126180 Camk1 Positive_regulation of Camkk1 1 0.16 0 0
67 INT292680 Negative_regulation of TXK Negative_regulation of ABL1 1 0.00 0.26 0
68 INT355603 Binding of CTNNA1 and Ctnnb1 1 0.00 1.07 0
69 INT350523 ABL1 Negative_regulation of Pmf1 1 0.01 2.19 0
70 INT355588 Binding of CDH1 and CTNNA1 1 0.00 1.12 0
71 INT175624 Gene_expression of CDH2 Positive_regulation of CDH1 1 0.00 1.12 0
72 INT350429 Negative_regulation of MAPK14 Regulation of Gene_expression of ATF3 1 0.12 0.78 0
73 INT234996 Ctnnd1 Positive_regulation of CDC42 1 0.01 0.07 0
74 INT209925 Binding of MAPK14 and IL1B 1 0.09 0 0
75 INT299628 MSTN Negative_regulation of Gene_expression of MYOD1 1 0.09 0.15 0
76 INT285582 Binding of ABL1 and S100A8 1 0.02 0.2 0
77 INT194675 MAPK14 Positive_regulation of CREB1 1 0.07 0.33 0
78 INT194684 MAPK14 Positive_regulation of Transcription of CREB1 1 0.07 0.33 0
79 INT320554 Mapk14 Positive_regulation of MEF2A 1 0.26 1.31 0
80 INT292726 ABL1 Positive_regulation of Mapk1 1 0.01 0.15 0
81 INT350504 ABL1 Negative_regulation of JAK2 1 0.20 2.18 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of muscle cell differentiation. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of muscle cell differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT86534 Positive_regulation of MAPK14 81 0.62 57.81 23.62
2 INT69322 Negative_regulation of MAPK14 70 0.54 42.92 22.71
3 INT171924 Gene_expression of MAPK14 60 0.65 54.38 21.68
4 INT110178 Phosphorylation of MAPK14 40 0.68 19.38 10.37
5 INT85126 Negative_regulation of MAP2K6 19 0.39 12.12 4.39
6 INT117920 Regulation of MAPK14 14 0.38 8.75 4.31
7 INT117921 Positive_regulation of Positive_regulation of MAPK14 9 0.44 9.93 4.18
8 INT119420 Phosphorylation of MAP2K6 8 0.79 4.89 3.52
9 INT77981 Negative_regulation of BOC 2 0.42 0 3.39
10 INT173179 Binding of MAPK14 13 0.29 4.51 2.92
11 INT102646 Positive_regulation of MAP2K6 3 0.63 4.37 2.44
12 INT110179 Negative_regulation of Phosphorylation of MAPK14 11 0.36 5.25 2.38
13 INT291336 Gene_expression of MAP2K6 4 0.70 7.8 2.13
14 INT173647 Positive_regulation of Gene_expression of MAPK14 15 0.39 7.54 2.05
15 INT119422 Negative_regulation of Phosphorylation of MAP2K6 3 0.38 2.09 1.76
16 INT173173 Regulation of Positive_regulation of MAPK14 6 0.38 2.59 1.64
17 INT182297 Positive_regulation of Phosphorylation of MAPK14 7 0.42 3.36 1.53
18 INT109916 Positive_regulation of Positive_regulation of MAP2K6 2 0.45 2.28 1.45
19 INT173654 Localization of MAPK14 12 0.62 3.16 1.43
20 INT112823 Negative_regulation of Positive_regulation of MAPK14 5 0.36 1.49 1.22
21 INT97955 Positive_regulation of CDC42 8 0.49 2.47 1.19
22 INT123877 Negative_regulation of ABL1 40 0.57 27.94 1.17
23 INT150546 Positive_regulation of Phosphorylation of MAP2K6 3 0.49 1.14 0.93
24 INT194875 Regulation of Negative_regulation of MAPK14 1 0.04 2.39 0.91
25 INT346246 Positive_regulation of Gene_expression of MAP2K6 1 0.45 1.74 0.78
26 INT151468 Regulation of MAP2K6 2 0.11 0.68 0.74
27 INT125331 Gene_expression of BOC 4 0.58 0 0.69
28 INT139840 Positive_regulation of Negative_regulation of MAPK14 2 0.21 1.55 0.67
29 INT220662 Gene_expression of Camk1 3 0.66 3.17 0.58
30 INT111601 Negative_regulation of Gene_expression of CTNNA1 1 0.24 0.58 0.58
31 INT58742 Localization of MAP2K6 1 0.61 0.16 0.58
32 INT111609 Gene_expression of CTNNA1 3 0.46 3.2 0.57
33 INT97956 Negative_regulation of CDC42 3 0.27 1.58 0.55
34 INT146784 Gene_expression of MYOD1 13 0.74 4.41 0.54
35 INT209936 Negative_regulation of Gene_expression of MAPK14 7 0.20 4.95 0.53
36 INT114450 Gene_expression of Camk1 4 0.03 1.17 0.52
37 INT111606 Positive_regulation of CTNNA1 1 0.12 0.47 0.47
38 INT121027 Regulation of Phosphorylation of MAPK14 2 0.38 1.1 0.46
39 INT346258 Negative_regulation of Gene_expression of MAP2K6 1 0.38 1.08 0.45
40 INT346260 Regulation of Gene_expression of MAP2K6 1 0.41 1.09 0.45
41 INT173625 Positive_regulation of Localization of MAPK14 3 0.17 1.05 0.44
42 INT179170 Protein_catabolism of MAPK14 3 0.43 0.88 0.43
43 INT114447 Negative_regulation of Regulation of Camk1 1 0.00 0.72 0.43
44 INT114453 Regulation of Camk1 1 0.01 0.72 0.43
45 INT88005 Binding of MYOD1 6 0.30 2.08 0.42
46 INT255902 Positive_regulation of Binding of MAPK14 1 0.17 0.93 0.42
47 INT117662 Gene_expression of ABL1 21 0.69 18.76 0.39
48 INT73854 Transcription of ABL1 4 0.52 2.26 0.34
49 INT114448 Regulation of Gene_expression of Camk1 1 0.01 0.52 0.3
50 INT255923 Positive_regulation of Regulation of MAPK14 1 0.17 0.41 0.28
51 INT185719 Regulation of Gene_expression of MYOD1 1 0.07 0 0.24
52 INT183881 Localization of CDC42 3 0.49 1.92 0.23
53 INT114452 Regulation of Regulation of Camk1 1 0.00 0.38 0.22
54 INT183876 Regulation of CDC42 3 0.30 1.94 0.19
55 INT239412 Binding of ABL1 8 0.28 5.39 0.18
56 INT173653 Positive_regulation of CDH2 3 0.06 1.77 0.18
57 INT2240 Regulation of CDON 1 0.00 0 0.18
58 INT251938 Positive_regulation of Gene_expression of MEF2A 1 0.12 0.14 0.17
59 INT251939 Gene_expression of MEF2A 1 0.18 0.14 0.16
60 INT267610 Negative_regulation of Negative_regulation of MAPK14 1 0.03 1.08 0.15
61 INT283174 Negative_regulation of Gene_expression of BOC 1 0.04 0 0.15
62 INT163461 Regulation of ABL1 8 0.32 5.98 0.14
63 INT2239 Localization of CDON 1 0.01 0 0.14
64 INT114451 Negative_regulation of Camk1 1 0.00 0.35 0.14
65 INT249108 Regulation of MEF2A 1 0.17 0.28 0.14
66 INT114449 Negative_regulation of Gene_expression of Camk1 1 0.00 0.34 0.13
67 INT206133 Binding of CDC42 3 0.25 0.8 0.12
68 INT219214 Positive_regulation of Gene_expression of MYOD1 1 0.35 0.21 0.12
69 INT346252 Regulation of Gene_expression of MAPK14 1 0.38 0 0.09
70 INT163462 Negative_regulation of Regulation of ABL1 1 0.11 1.17 0.06
71 INT109594 Positive_regulation of ABL1 10 0.49 7.19 0.05
72 INT206169 Gene_expression of CDC42 2 0.26 1.05 0.05
73 INT206167 Positive_regulation of Gene_expression of CDC42 1 0.08 0.05 0.05
74 INT201818 Regulation of CDH2 3 0.09 1.89 0.04
75 INT182288 Negative_regulation of Binding of MAPK14 1 0.21 0.08 0.04
76 INT350897 Negative_regulation of Binding of ABL1 1 0.18 1.19 0.04
77 INT182280 Negative_regulation of Localization of MAPK14 1 0.21 0.39 0.04
78 INT234417 Positive_regulation of Gene_expression of ABL1 4 0.37 3.65 0.03
79 INT175651 Gene_expression of CDH2 5 0.36 2.59 0
80 INT201814 Negative_regulation of CDH2 4 0.20 0.25 0
81 INT292713 Phosphorylation of ABL1 2 0.44 1.04 0
82 INT299630 Negative_regulation of Gene_expression of MYOD1 1 0.16 0.15 0
83 INT173646 Binding of CDH2 1 0.05 0.23 0
84 INT320531 Transcription of MEF2A 1 0.23 1.54 0
85 INT227665 Transcription of MYOD1 1 0.23 0.3 0
86 INT350510 Localization of ABL1 1 0.40 2.51 0
87 INT292711 Regulation of Gene_expression of ABL1 1 0.06 1.02 0
88 INT201811 Negative_regulation of Gene_expression of CDH2 1 0.12 0.09 0
89 INT350521 Negative_regulation of Negative_regulation of ABL1 1 0.23 0.55 0
90 INT287281 Positive_regulation of Positive_regulation of CDC42 1 0.26 0 0
91 INT156466 Regulation of Negative_regulation of ABL1 1 0.44 0.63 0
92 INT350517 Negative_regulation of Gene_expression of ABL1 1 0.23 0.53 0
93 INT165179 Regulation of Positive_regulation of ABL1 1 0.15 0.95 0
94 INT355598 Negative_regulation of CTNNA1 1 0.04 1.06 0
95 INT204718 Localization of MYOD1 1 0.29 0 0
96 INT298752 Negative_regulation of Camk1 1 0.37 0.74 0
97 INT201805 Negative_regulation of Negative_regulation of CDH2 1 0.09 0.25 0
98 INT320540 Positive_regulation of MEF2A 1 0.17 1.32 0
99 INT350512 Positive_regulation of Phosphorylation of ABL1 1 0.27 0.75 0
100 INT175643 Positive_regulation of Gene_expression of CDH2 1 0.04 1.11 0
101 INT351489 Regulation of Transcription of ABL1 1 0.28 0.08 0
102 INT350508 Protein_catabolism of ABL1 1 0.54 0.5 0
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