GO:0051219

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Name phosphoprotein binding
Categary Function
Go Slim No
Go Link GO:0051219
Unique Molecular Interactions 384
Total Molecular Interactions 488
Total Single Events 3103
Pain Genes Associated 46

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for phosphoprotein binding. They are ordered first by their pain relevance and then by number of times they were reported for phosphoprotein binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT275850 Binding of NDUFAB1 and SNCA 1 0.00 3.78 3.16
2 INT185143 Elane Positive_regulation of Pik3r1 1 0.01 0 1.72
3 INT54601 Binding of Mtor and Ache 1 0.20 0.8 1.58
4 INT112033 Gabrb3 Positive_regulation of Plcg1 1 0.05 0.18 1.49
5 INT112034 Gabrb3 Positive_regulation of Pik3r1 1 0.08 0.18 1.48
6 INT96262 Positive_regulation of Pik3cd Positive_regulation of Plcg1 1 0.03 0 1.39
7 INT168459 Sult1a1 Negative_regulation of Gene_expression of Arr3 1 0.05 2.98 1.23
8 INT228681 Fkbp4 Negative_regulation of Trib3 1 0.00 0.57 1.2
9 INT317564 Pik3r1 Regulation of Negative_regulation of Oprm1 1 0.13 0.07 1
10 INT265649 TBK1 Negative_regulation of COMT 1 0.01 0.61 0.94
11 INT72386 Egf Positive_regulation of Phosphorylation of Shc1 1 0.09 0.18 0.93
12 INT114883 Akt1 Regulation of Pik3r1 2 0.16 0.65 0.92
13 INT149386 Binding of Lyn and TRPV4 1 0.40 1.14 0.91
14 INT262564 Ngf Positive_regulation of Pik3r1 1 0.08 0.36 0.8
15 INT266102 Binding of PITX2 and RS1 1 0.00 0.64 0.8
16 INT85686 Binding of Arrb1 and Arrb2 1 0.14 0.09 0.79
17 INT168456 Arr3 Positive_regulation of Nos2 1 0.21 1.98 0.79
18 INT317573 Binding of Oprm1 and Pik3r1 1 0.12 0.33 0.71
19 INT317560 Binding of Pdpk1 and Pik3r1 1 0.13 0 0.65
20 INT309664 Binding of Pik3r1 and Cia1 1 0.02 1.32 0.64
21 INT116752 Ngf Regulation of Pik3r1 1 0.56 0.29 0.63
22 INT54942 Rb1 Regulation of Gab1 1 0.02 0.39 0.59
23 INT263975 NR4A3 Negative_regulation of Positive_regulation of TBK1 1 0.02 1.2 0.57
24 INT72387 Trim13 Regulation of Phosphorylation of Shc1 1 0.32 0.09 0.54
25 INT109307 Pik3r1 Positive_regulation of Phosphorylation of Akt1 1 0.29 0.4 0.53
26 INT292075 FSCN1 Positive_regulation of Gene_expression of Csnk1a1 1 0.03 0.57 0.52
27 INT317565 Oprm1 Positive_regulation of Pik3r1 1 0.14 0.05 0.52
28 INT308656 Pik3r1 Positive_regulation of Nos3 1 0.02 1.8 0.5
29 INT96282 Cav2 Regulation of Positive_regulation of Gabrg1 1 0.25 0 0.48
30 INT129551 Sag Negative_regulation of Gene_expression of Ptgs1 1 0.08 0.88 0.48
31 INT187100 Binding of Cd4 and Cd44 1 0.02 1.09 0.47
32 INT341211 Gopc Regulation of Shc1 1 0.02 0.68 0.45
33 INT304281 IL8 Positive_regulation of TBK1 1 0.01 2.35 0.44
34 INT148548 Cd44 Positive_regulation of Regulation of NPEPPS 1 0.00 0.29 0.42
35 INT273111 Bdnf Positive_regulation of Positive_regulation of Mtor 1 0.44 0.07 0.42
36 INT326303 Binding of CRP and FKBP4 1 0.15 1.22 0.41
37 INT261790 SHC1 Positive_regulation of Slc12a5 1 0.02 0.06 0.41
38 INT148547 Cd44 Positive_regulation of NPEPPS 1 0.00 0.29 0.41
39 INT348031 Binding of Irf3 and Tbk1 1 0.17 2.82 0.4
40 INT166157 Ccr9 Positive_regulation of Pik3r1 1 0.55 2.14 0.39
41 INT353391 Binding of DRD4 and GRB2 1 0.37 0.62 0.37
42 INT277353 VEGFA Regulation of Mtor 1 0.02 1.11 0.37
43 INT277354 Gene_expression of VEGFA Regulation of Mtor 1 0.02 1.1 0.37
44 INT85782 Rb1 Regulation of PRKG1 1 0.00 0.38 0.37
45 INT85778 Rb1 Regulation of Prkaca 1 0.00 0.38 0.36
46 INT85779 Rb1 Regulation of Prkcg 1 0.01 0.38 0.36
47 INT183784 INS Negative_regulation of Binding of TBK1 1 0.01 1.81 0.34
48 INT183783 INS Negative_regulation of TBK1 1 0.01 1.81 0.34
49 INT257746 SHC1 Positive_regulation of Positive_regulation of PIK3CA 1 0.26 1.04 0.34
50 INT183782 INS Negative_regulation of Gene_expression of TBK1 1 0.01 1.81 0.34
51 INT204080 HP Negative_regulation of Phosphorylation of Rb1 1 0.00 3.53 0.34
52 INT288200 Tlr2 Positive_regulation of Pik3r1 1 0.05 0.24 0.33
53 INT168779 Binding of Pik3r1 and Tnf 1 0.01 0.73 0.33
54 INT273118 Bdnf Positive_regulation of Mtor 1 0.66 0 0.33
55 INT255740 Pik3r1 Positive_regulation of Akt1 5 0.24 2.42 0.31
56 INT257743 Binding of PIK3CA and SHC1 1 0.21 1.03 0.31
57 INT318323 Binding of GRB2 and HSPA5 1 0.34 0.28 0.31
58 INT54943 Gab1 Regulation of Rb1 1 0.02 0.2 0.31
59 INT150050 Mtor Positive_regulation of Rps6kb1 3 0.49 1.44 0.3
60 INT328407 Nlrp1a Negative_regulation of Gene_expression of Snca 1 0.07 0.31 0.29
61 INT191692 Binding of Bag1 and gr 1 0.07 0.76 0.29
62 INT328410 Nlrp1a Negative_regulation of Snca 1 0.07 0.31 0.29
63 INT185141 Pik3r1 Positive_regulation of Snrpd1 1 0.00 0.16 0.29
64 INT49904 Gtf3a Regulation of Dpys 1 0.02 0.06 0.28
65 INT257744 Binding of PIK3R2 and SHC1 1 0.08 0.96 0.28
66 INT296794 Positive_regulation of Tlr2 Positive_regulation of Pik3r1 1 0.10 1.02 0.26
67 INT131963 Binding of CAV2 and ATXN2 1 0.04 1.39 0.21
68 INT139454 Binding of IGF2R and Icam1 1 0.00 0.4 0.21
69 INT191685 Bag1 Regulation of gr 1 0.08 1.1 0.21
70 INT121807 CACNA1A Regulation of CAV2 1 0.01 0.25 0.2
71 INT348014 Binding of Tbk1 and Gramd3 1 0.00 1.33 0.2
72 INT121806 PHF21A Regulation of CAV2 1 0.00 0.24 0.2
73 INT291348 IL8 Positive_regulation of Phosphorylation of SHC1 1 0.11 1.16 0.2
74 INT348013 Negative_regulation of Binding of Irf3 and Tbk1 1 0.21 1.41 0.2
75 INT262224 Sfn Negative_regulation of Transcription of CYP3A4 1 0.06 0.58 0.2
76 INT343644 Grm5 Positive_regulation of Cav2 1 0.05 0 0.19
77 INT149096 PITX2 Positive_regulation of Gene_expression of Egr1 1 0.01 1.23 0.19
78 INT314038 THL Negative_regulation of Pik3r1 1 0.14 0.78 0.18
79 INT24475 Dpys Regulation of Brs3 1 0.18 0 0.18
80 INT135973 Dpys Negative_regulation of Gene_expression of Nos2 1 0.06 0.26 0.17
81 INT317322 Snca Regulation of Positive_regulation of Th 1 0.01 0.23 0.17
82 INT119264 Binding of RB1 and PPM1E 1 0.00 0.46 0.17
83 INT135970 Dpys Negative_regulation of Nos2 1 0.05 0.25 0.17
84 INT191688 Igh-Dex Regulation of Gene_expression of Bag1 1 0.04 1.21 0.16
85 INT349560 Olr779 Negative_regulation of Mtor 1 0.02 0.5 0.16
86 INT191355 HDAC4 Positive_regulation of Gene_expression of Shc1 1 0.02 1.07 0.16
87 INT221899 Rb1 Positive_regulation of Transcription of Ccl20 1 0.01 0.62 0.16
88 INT221908 Rb1 Positive_regulation of Transcription of TNIP2 1 0.01 0.62 0.16
89 INT341818 Binding of PITX2 and Aia1 1 0.00 0.53 0.16
90 INT191354 Negative_regulation of HDAC4 Positive_regulation of Gene_expression of Shc1 1 0.02 1.07 0.16
91 INT149095 PITX2 Positive_regulation of Casp3 1 0.00 1.51 0.15
92 INT149092 PITX2 Positive_regulation of RFFL 1 0.00 1.51 0.15
93 INT255258 Binding of Rb1 and Tsp1 1 0.38 0.95 0.15
94 INT310263 Rb1 Negative_regulation of Gene_expression of Tnf 1 0.07 0.97 0.15
95 INT350081 Pik3r1 Positive_regulation of Hmox1 1 0.07 0.2 0.15
96 INT273902 Mtor Positive_regulation of Eif4ebp1 1 0.50 0.56 0.15
97 INT349559 Mtor Regulation of Pdpk1 1 0.03 0.42 0.14
98 INT262231 Sfn Negative_regulation of Gene_expression of CYP3A4 1 0.06 0.26 0.14
99 INT273901 Mtor Positive_regulation of Eif4e 1 0.50 0.54 0.14
100 INT262193 Binding of Nr1i2 and Sfn 1 0.15 0.26 0.13
101 INT129094 Binding of GRP and Pik3r1 1 0.00 0.49 0.12
102 INT129091 Binding of PIK3CG and Lyn 1 0.00 0.47 0.12
103 INT129075 Binding of Pik3r1 and Lyn 1 0.00 0.47 0.12
104 INT166153 Pik3r1 Regulation of Gene_expression of Ccr9 1 0.36 0.78 0.12
105 INT262206 Sfn Negative_regulation of Nr1i2 1 0.17 0.28 0.12
106 INT129093 Binding of Lyn and TCHP 1 0.00 0.49 0.12
107 INT129092 Binding of GRP and Lyn 1 0.00 0.48 0.12
108 INT317888 Binding of Eef1a1 and Pik3r1 1 0.01 1.04 0.11
109 INT273103 Binding of Mtor and Rps6kb1 1 0.44 0 0.11
110 INT317887 Binding of Mtf1 and Pik3r1 1 0.25 1.04 0.11
111 INT158141 Binding of HOXD13 and SNCA 1 0.54 0.41 0.11
112 INT268943 Binding of Crmp1 and Positive_regulation of Regulation of Ros1 1 0.00 0.2 0.11
113 INT273112 Positive_regulation of Binding of Mtor and Rps6kb1 1 0.46 0.05 0.11
114 INT191184 Binding of EGFR and GRB2 7 0.35 1.06 0.1
115 INT313482 Binding of MTOR and SST 1 0.01 0 0.1
116 INT328413 Binding of Snca and Nlrp1a 1 0.06 0.75 0.1
117 INT291351 Binding of EGFR and SHC1 1 0.05 0.57 0.1
118 INT347647 Inpp5d Negative_regulation of Pik3r1 1 0.31 0.37 0.1
119 INT263449 Binding of NFKBIA and TBK1 1 0.07 0.2 0.1
120 INT204899 Tlr4 Positive_regulation of Cd44 1 0.23 0.09 0.09
121 INT204885 Tlr4 Negative_regulation of Positive_regulation of Cd44 1 0.21 0.09 0.09
122 INT213051 Hdl1 Positive_regulation of Pik3r1 1 0.13 1.93 0.09
123 INT83270 Snca Regulation of Napepld 1 0.14 0 0.09
124 INT204889 Tlr4 Negative_regulation of Cd44 1 0.10 0.09 0.09
125 INT238392 RB1 Regulation of E2F2 1 0.01 0.36 0.08
126 INT255256 Positive_regulation of Binding of Rb1 and Tsp1 1 0.50 0.48 0.08
127 INT249126 Binding of Ephb1 and Mtor 1 0.02 0 0.08
128 INT207310 Pik3r1 Positive_regulation of Prnp 1 0.36 0.65 0.08
129 INT273104 Mtor Negative_regulation of Gene_expression of Gria1 1 0.46 0.15 0.08
130 INT191757 ROS1 Positive_regulation of TBK1 1 0.00 0.6 0.08
131 INT331796 Akt1 Negative_regulation of Negative_regulation of Pik3r1 1 0.04 0.88 0.08
132 INT340553 Pik3r1 Regulation of Gene_expression of Fbxo32 1 0.04 0.52 0.07
133 INT340317 Binding of Shc1 and Positive_regulation of Frs2 1 0.19 0 0.07
134 INT273107 Bdnf Regulation of Positive_regulation of Mtor 1 0.26 0.09 0.07
135 INT340320 Binding of Shc1 and Positive_regulation of Pik3r1 1 0.23 0 0.07
136 INT120569 Binding of Egfr and Pik3r1 1 0.40 1.22 0.06
137 INT346452 TLR3 Positive_regulation of TBK1 1 0.03 0.45 0.06
138 INT120570 Positive_regulation of Binding of Egfr and Pik3r1 1 0.55 1.22 0.06
139 INT339099 ERBB2 Positive_regulation of IGF2R 1 0.33 0.67 0.06
140 INT346449 TICAM1 Positive_regulation of TBK1 1 0.01 0.45 0.06
141 INT76862 Dynll1 Positive_regulation of Rb1 1 0.37 0.1 0.06
142 INT257867 Negative_regulation of Eif4e Positive_regulation of Rb1 1 0.05 0.54 0.06
143 INT197617 Binding of S100a6 and Rb1 1 0.03 0 0.06
144 INT273098 Binding of Bdnf and Positive_regulation of Mtor 1 0.47 0 0.06
145 INT244641 PDGFA Regulation of MTOR 1 0.07 2.55 0.06
146 INT221658 Sema3a Positive_regulation of Phosphorylation of Crmp1 1 0.12 0.4 0.05
147 INT298806 Binding of Hdac3 and Rb1 1 0.02 0.77 0.05
148 INT73194 GRB2 Positive_regulation of Positive_regulation of PLCG2 1 0.19 0.81 0.05
149 INT273096 Mtor Positive_regulation of Gene_expression of Grip2 1 0.05 0.07 0.05
150 INT213016 Regulation of Hdl1 Positive_regulation of Pik3r1 1 0.09 0.97 0.05
151 INT329216 Prkag1 Regulation of Mtor 1 0.01 0.35 0.04
152 INT253376 Lep Regulation of Mtor 1 0.17 0.08 0.04
153 INT352612 Trp53 Negative_regulation of Cd44 1 0.24 1.01 0.04
154 INT199106 Negative_regulation of Pik3r1 Negative_regulation of Gene_expression of Ros1 1 0.03 0.08 0.04
155 INT257874 Agt Positive_regulation of Mtor 1 0.04 0.37 0.04
156 INT213031 Positive_regulation of Pik3r1 Positive_regulation of Gene_expression of Nos3 1 0.10 0.8 0.04
157 INT169962 Binding of Rb1 and E2f4 1 0.25 0.56 0.04
158 INT200645 Binding of AKT1 and TBK1 1 0.02 0.43 0.04
159 INT221654 Fes Positive_regulation of Phosphorylation of Crmp1 1 0.18 0.37 0.04
160 INT257881 Ins1 Positive_regulation of Mtor 1 0.05 0.37 0.04
161 INT333559 TBK1 Regulation of Phosphorylation of IRF3 1 0.17 0.35 0.04
162 INT333848 Binding of Ccna1 and Rb1 1 0.04 0.48 0.04
163 INT234991 Binding of Dsg3 and Positive_regulation of Pik3r1 1 0.05 0.32 0.03
164 INT253573 Binding of Jak2 and Pik3r1 1 0.06 0 0.03
165 INT257866 Phosphorylation of Rraga Positive_regulation of Pik3cg 1 0.03 0.63 0.03
166 INT263453 Binding of GRP and TBK1 1 0.00 0.07 0.03
167 INT332286 PIK3CD Positive_regulation of MTOR 1 0.14 0.73 0.03
168 INT255756 Ptch1 Positive_regulation of Phosphorylation of Pik3r1 1 0.16 1.08 0.03
169 INT257876 Rraga Positive_regulation of Pik3cg 1 0.03 0.63 0.03
170 INT298878 Binding of MTOR and RAB7A 1 0.07 0.35 0.03
171 INT255733 Ptch1 Positive_regulation of Pik3r1 1 0.16 1.08 0.03
172 INT197587 Ppt1 Positive_regulation of Rb1 1 0.18 0 0.03
173 INT256549 Binding of Pten and Mtor 1 0.00 1.02 0.03
174 INT333878 Shc1 Positive_regulation of EPHB2 1 0.08 0.3 0.03
175 INT257880 Ins1 Positive_regulation of Phosphorylation of Rraga 1 0.01 0.68 0.03
176 INT197593 Dlat Positive_regulation of Rb1 1 0.04 0 0.03
177 INT94157 CDCP1 Negative_regulation of RB1 1 0.02 0.92 0.03
178 INT200814 Epo Positive_regulation of Lyn 1 0.36 1.42 0.03
179 INT241450 Binding of Rhoa and Dpysl3 1 0.02 0 0.03
180 INT287479 PSMB10 Positive_regulation of TBK1 1 0.00 0.59 0.03
181 INT94159 Positive_regulation of CDK1 Negative_regulation of RB1 1 0.45 0.93 0.03
182 INT262150 Binding of Rare1 and Sfn 1 0.01 0.33 0.03
183 INT313485 MTOR Positive_regulation of Gene_expression of P2RX1 1 0.16 0 0.03
184 INT273105 Mtor Regulation of Gria1 1 0.29 0.07 0.03
185 INT94158 CDK1 Negative_regulation of RB1 1 0.41 0.92 0.03
186 INT287480 Protein_catabolism of NFKBIB Positive_regulation of TBK1 1 0.01 0.6 0.03
187 INT268942 Binding of Crmp1 and Fig4 1 0.01 0.28 0.03
188 INT238393 Binding of E2F2 and RB1 3 0.04 0.24 0
189 INT176543 Binding of Cd44 and Spp1 2 0.31 0.57 0
190 INT306646 Mapk1 Regulation of Pik3r1 1 0.03 0.39 0
191 INT198009 MTOR Regulation of HCC 1 0.09 1.1 0
192 INT319686 Positive_regulation of Sfn Positive_regulation of Nfe2l2 1 0.18 0 0
193 INT225610 Ncoa6 Regulation of Rb1 1 0.03 0.21 0
194 INT253359 Positive_regulation of Prkaa2 Negative_regulation of Mtor 1 0.26 0.27 0
195 INT339047 Binding of PITX2 and SNRNP70 1 0.00 0.52 0
196 INT313597 Binding of BRCA2 and TOX3 1 0.11 0.7 0
197 INT191097 Neu1 Positive_regulation of Shc1 1 0.04 1.96 0
198 INT325945 Binding of Cd44 and Ezr 1 0.25 0.39 0
199 INT287676 Negative_regulation of Sphk1 Negative_regulation of Pik3r1 1 0.14 0.42 0
200 INT225909 Binding of GRB2 and SOS1 1 0.01 0.11 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for phosphoprotein binding. They are ordered first by their pain relevance and then by number of times they were reported in phosphoprotein binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT112029 Positive_regulation of Pik3r1 90 0.67 38.76 20.95
2 INT292049 Gene_expression of Csnk1a1 1 0.59 28.22 19.53
3 INT112027 Gene_expression of Pik3r1 58 0.75 30.9 15.95
4 INT123593 Gene_expression of Snca 58 0.78 35.76 12.87
5 INT114420 Negative_regulation of Pik3r1 67 0.54 34.86 12.82
6 INT96259 Positive_regulation of Plcg1 11 0.49 3.01 11.15
7 INT15305 Positive_regulation of Mtor 51 0.67 8.28 11
8 INT20166 Negative_regulation of Mtor 32 0.56 10.64 10.25
9 INT127123 Positive_regulation of Snca 35 0.70 14.76 10.1
10 INT15307 Regulation of Mtor 27 0.48 4.7 9.34
11 INT110004 Gene_expression of Plcg1 7 0.41 2.61 7.87
12 INT49464 Positive_regulation of Dpys 7 0.47 0.5 6.96
13 INT292062 Negative_regulation of Csnk1a1 1 0.44 7.57 6.52
14 INT97145 Positive_regulation of TBK1 14 0.12 15.32 5.43
15 INT183467 Negative_regulation of TBK1 6 0.12 9.89 5.41
16 INT292072 Positive_regulation of Gene_expression of Csnk1a1 1 0.53 9.76 5.39
17 INT24080 Negative_regulation of Mtor 64 0.37 41.56 5.19
18 INT23611 Gene_expression of Mtor 23 0.66 3.57 5.02
19 INT116744 Binding of Pik3r1 22 0.36 12.77 5.01
20 INT116748 Positive_regulation of Gene_expression of Pik3r1 18 0.49 9.83 4.63
21 INT123594 Negative_regulation of Snca 19 0.59 4.43 4.59
22 INT292060 Positive_regulation of Csnk1a1 1 0.53 6.03 4.57
23 INT127122 Positive_regulation of Gene_expression of Snca 11 0.69 15.36 4.56
24 INT67144 Gene_expression of Cd44 17 0.76 8.94 4.48
25 INT116747 Regulation of Pik3r1 18 0.60 9.33 4.34
26 INT292057 Regulation of Csnk1a1 1 0.34 3.52 4.33
27 INT48411 Gene_expression of Cd44 35 0.77 27.05 4.29
28 INT72385 Phosphorylation of Shc1 11 0.52 1.62 4.1
29 INT146946 Gene_expression of Lyn 16 0.76 8.9 3.75
30 INT119412 Gene_expression of Snca 15 0.66 11.27 3.39
31 INT110245 Gene_expression of SNCA 11 0.77 8.29 3.36
32 INT94164 Phosphorylation of RB1 83 0.80 48.84 3.21
33 INT165911 Localization of Pik3r1 15 0.51 7.94 3.2
34 INT292056 Localization of Csnk1a1 1 0.57 3.99 3.17
35 INT29929 Gene_expression of Rb1 20 0.69 5.81 3.1
36 INT123595 Regulation of Snca 7 0.62 4.3 3.06
37 INT92335 Gene_expression of TBK1 11 0.28 8.98 3
38 INT72384 Positive_regulation of Phosphorylation of Shc1 1 0.32 0.48 2.9
39 INT108793 Gene_expression of PITX2 12 0.75 3.91 2.89
40 INT292058 Positive_regulation of Cav2 7 0.67 3.43 2.89
41 INT41721 Negative_regulation of MTOR 40 0.58 32.49 2.83
42 INT228678 Phosphorylation of Mtor 15 0.78 3.18 2.76
43 INT149314 Negative_regulation of CAV2 5 0.42 1.21 2.76
44 INT97132 Negative_regulation of Positive_regulation of TBK1 5 0.08 6.54 2.76
45 INT282270 Gene_expression of Cav2 11 0.57 3.53 2.72
46 INT54938 Regulation of Rb1 6 0.44 4.41 2.69
47 INT176531 Gene_expression of SHC1 3 0.67 9.5 2.62
48 INT237655 Binding of Sfn 1 0.42 3.62 2.55
49 INT136681 Gene_expression of Shc1 13 0.77 9.67 2.52
50 INT292070 Binding of Csnk1a1 1 0.28 3.18 2.5
51 INT49896 Regulation of Dpys 5 0.58 0.16 2.41
52 INT57970 Positive_regulation of Rb1 17 0.67 7.03 2.36
53 INT183468 Localization of TBK1 6 0.32 4.35 2.36
54 INT109305 Phosphorylation of Pik3r1 13 0.53 5.69 2.32
55 INT73266 Gene_expression of RB1 50 0.70 29.09 2.31
56 INT228675 Binding of Fkbp4 1 0.01 1.14 2.28
57 INT237653 Gene_expression of Sfn 6 0.59 5.54 2.26
58 INT146945 Positive_regulation of Lyn 6 0.49 2.81 2.25
59 INT151878 Gene_expression of CAV2 18 0.66 9.26 2.17
60 INT114421 Positive_regulation of Positive_regulation of Pik3r1 9 0.49 4.07 2.13
61 INT55470 Regulation of Mtor 16 0.24 12.51 2.07
62 INT36293 Gene_expression of Mtor 24 0.25 14.5 2.04
63 INT127124 Regulation of Gene_expression of Snca 2 0.62 0.17 2.03
64 INT287525 Localization of CAV2 5 0.47 5.32 2
65 INT191674 Gene_expression of Bag1 8 0.51 5.91 1.98
66 INT110003 Phosphorylation of Plcg1 2 0.37 0.91 1.96
67 INT122534 Binding of Shc1 6 0.48 3.59 1.94
68 INT292051 Negative_regulation of Cav2 6 0.41 2.52 1.9
69 INT127125 Localization of Snca 6 0.81 8.24 1.88
70 INT257755 Positive_regulation of SHC1 1 0.60 4.97 1.87
71 INT148266 Positive_regulation of SNCA 5 0.67 3.17 1.74
72 INT257820 Positive_regulation of PAFAH1B1 1 0.68 11.09 1.69
73 INT57971 Regulation of Rb1 5 0.41 2.36 1.66
74 INT292052 Regulation of Gene_expression of Csnk1a1 1 0.47 2.5 1.62
75 INT94169 Negative_regulation of Phosphorylation of RB1 16 0.41 8.87 1.57
76 INT136680 Negative_regulation of Gene_expression of Shc1 4 0.43 3.36 1.57
77 INT173716 Positive_regulation of Cd44 7 0.44 4.65 1.45
78 INT201271 Phosphorylation of Snca 3 0.82 4.22 1.45
79 INT41719 Gene_expression of MTOR 27 0.77 19.43 1.44
80 INT258048 Regulation of TBK1 4 0.05 3.81 1.44
81 INT136678 Positive_regulation of Gene_expression of Shc1 4 0.50 2.93 1.42
82 INT166764 Localization of Mtor 2 0.75 1.28 1.42
83 INT124247 Negative_regulation of Gene_expression of Snca 12 0.59 3.87 1.39
84 INT109301 Positive_regulation of Phosphorylation of Pik3r1 5 0.42 1.45 1.38
85 INT9888 Gene_expression of Arr3 2 0.51 3.34 1.38
86 INT169907 Gene_expression of Rb1 25 0.60 21.95 1.32
87 INT63905 Regulation of RB1 13 0.62 12.67 1.28
88 INT22815 Positive_regulation of RB1 20 0.49 14.58 1.26
89 INT123924 Positive_regulation of Gene_expression of Cd44 2 0.46 1.11 1.25
90 INT210399 Gene_expression of IGF2R 22 0.65 17.1 1.23
91 INT41124 Negative_regulation of Rb1 11 0.44 3.17 1.22
92 INT110001 Binding of Plcg1 2 0.36 0.44 1.21
93 INT228671 Negative_regulation of Phosphorylation of Mtor 8 0.50 1.77 1.2
94 INT110244 Positive_regulation of Gene_expression of SNCA 5 0.69 4.66 1.19
95 INT183790 Binding of TBK1 2 0.04 2.97 1.16
96 INT100154 Regulation of PITX2 5 0.60 0.48 1.15
97 INT151753 Transcription of Snca 6 0.69 1.99 1.11
98 INT135390 Binding of Cd44 3 0.45 1.91 1.09
99 INT292071 Regulation of Negative_regulation of Csnk1a1 1 0.34 0.64 1.07
100 INT292945 Positive_regulation of Positive_regulation of Snca 4 0.69 2.42 1.05
101 INT274898 Positive_regulation of Positive_regulation of Lyn 1 0.35 1.51 1.05
102 INT257750 Positive_regulation of Gene_expression of SHC1 1 0.60 3.1 1.04
103 INT286344 Positive_regulation of Gene_expression of Snca 1 0.41 2.84 1.03
104 INT110000 Positive_regulation of Phosphorylation of Plcg1 1 0.23 0.49 1.02
105 INT151774 Positive_regulation of Mtor 38 0.45 20.15 1.01
106 INT24809 Positive_regulation of Fkbp4 3 0.40 1.57 1
107 INT257824 Localization of PAFAH1B1 1 0.74 6.58 1
108 INT77639 Phosphorylation of Plcg1 5 0.68 0.47 0.97
109 INT108795 Transcription of PITX2 1 0.69 0.46 0.96
110 INT146939 Negative_regulation of Lyn 3 0.53 2.97 0.95
111 INT292066 Negative_regulation of Gene_expression of Csnk1a1 1 0.32 2.01 0.95
112 INT174188 Positive_regulation of Gene_expression of RB1 9 0.45 6.22 0.94
113 INT135392 Localization of Cd44 1 0.75 1.74 0.93
114 INT292059 Positive_regulation of Gene_expression of Cav2 3 0.42 0.88 0.92
115 INT151752 Positive_regulation of Transcription of Snca 2 0.50 0.99 0.92
116 INT22991 Gene_expression of Dpys 3 0.73 0.08 0.91
117 INT149383 Binding of Lyn 1 0.36 1.14 0.91
118 INT124246 Binding of Snca 10 0.37 6.53 0.9
119 INT108520 Negative_regulation of Dpys 2 0.12 0.21 0.9
120 INT292067 Negative_regulation of Negative_regulation of Csnk1a1 1 0.32 0.56 0.9
121 INT292063 Positive_regulation of Positive_regulation of Csnk1a1 1 0.38 1.46 0.9
122 INT138980 Binding of PITX2 15 0.47 10.34 0.88
123 INT139449 Negative_regulation of IGF2R 5 0.15 2.58 0.87
124 INT292048 Transcription of Csnk1a1 1 0.52 1.44 0.82
125 INT288191 Positive_regulation of Localization of Pik3r1 4 0.15 1.27 0.81
126 INT263481 Regulation of Positive_regulation of TBK1 1 0.07 1.28 0.81
127 INT169911 Phosphorylation of Rb1 35 0.73 18.58 0.79
128 INT271917 Phosphorylation of Mtor 11 0.13 6.76 0.78
129 INT352771 Positive_regulation of Localization of TBK1 1 0.05 0.98 0.78
130 INT85678 Binding of Arrb1 1 0.20 0.09 0.78
131 INT72380 Positive_regulation of Shc1 10 0.69 6.87 0.77
132 INT204842 Positive_regulation of Cd44 9 0.49 6.6 0.77
133 INT180752 Gene_expression of PAFAH1B1 3 0.66 9.89 0.75
134 INT152326 Regulation of Gene_expression of CAV2 2 0.36 0.44 0.74
135 INT49903 Transcription of Dpys 1 0.67 0.25 0.74
136 INT41123 Positive_regulation of Rb1 12 0.44 3.03 0.73
137 INT151877 Positive_regulation of Gene_expression of CAV2 2 0.40 0.39 0.72
138 INT213923 Positive_regulation of MTOR 16 0.65 9.28 0.7
139 INT187096 Negative_regulation of Cd44 6 0.30 5.92 0.7
140 INT257817 Regulation of PAFAH1B1 1 0.60 4.93 0.7
141 INT314571 Binding of Tbk1 3 0.24 2.88 0.69
142 INT333595 Negative_regulation of Gene_expression of TBK1 2 0.12 0.91 0.67
143 INT187087 Binding of Cd44 5 0.47 2.79 0.66
144 INT15303 Transcription of Mtor 1 0.47 0.17 0.66
145 INT15302 Regulation of Transcription of Mtor 1 0.31 0.17 0.66
146 INT169931 Localization of Rb1 6 0.70 4.79 0.65
147 INT166456 Negative_regulation of Gene_expression of Pik3r1 4 0.41 1.72 0.64
148 INT191347 Regulation of Shc1 6 0.27 3.6 0.6
149 INT135666 Negative_regulation of Negative_regulation of Pik3r1 2 0.29 0.3 0.6
150 INT288158 Negative_regulation of Gene_expression of Cd44 5 0.30 5.73 0.59
151 INT110002 Regulation of Positive_regulation of Plcg1 1 0.11 0.4 0.59
152 INT121810 Positive_regulation of CAV2 2 0.28 0.55 0.57
153 INT117091 Positive_regulation of Lyn 1 0.49 0.41 0.56
154 INT62266 Phosphorylation of Rb1 4 0.71 2.68 0.54
155 INT315028 Regulation of Cav2 2 0.43 0.86 0.54
156 INT139743 Binding of Sag 2 0.16 2.33 0.54
157 INT190864 Positive_regulation of Phosphorylation of Tbk1 1 0.08 0.68 0.53
158 INT190859 Phosphorylation of Tbk1 1 0.12 0.68 0.52
159 INT94165 Negative_regulation of RB1 30 0.52 27.29 0.51
160 INT136679 Negative_regulation of Shc1 3 0.59 2.5 0.51
161 INT161248 Positive_regulation of Gene_expression of Mtor 2 0.06 6.47 0.51
162 INT223599 Regulation of MTOR 14 0.42 8.52 0.49
163 INT72379 Localization of Shc1 4 0.74 0.89 0.49
164 INT237651 Negative_regulation of Sfn 3 0.51 1.7 0.49
165 INT200677 Transcription of TBK1 2 0.14 0.74 0.49
166 INT257816 Negative_regulation of PAFAH1B1 1 0.58 3.66 0.49
167 INT279363 Binding of FKBP4 1 0.05 0.22 0.49
168 INT49465 Binding of Dpys 1 0.26 0.1 0.49
169 INT298539 Binding of CAV2 2 0.39 0.95 0.48
170 INT93397 Negative_regulation of Phosphorylation of Rb1 1 0.51 0.32 0.48
171 INT253391 Positive_regulation of Positive_regulation of Mtor 7 0.48 0.39 0.46
172 INT263479 Positive_regulation of Transcription of TBK1 1 0.12 0.32 0.46
173 INT183470 Positive_regulation of Negative_regulation of TBK1 1 0.08 0.46 0.46
174 INT342920 Localization of Dpys 1 0.73 1.41 0.44
175 INT148264 Transcription of SNCA 1 0.40 0.25 0.42
176 INT257756 Regulation of Gene_expression of SHC1 1 0.39 1.13 0.41
177 INT194993 Binding of RB1 15 0.37 10.96 0.4
178 INT196916 Negative_regulation of Rb1 13 0.42 14.29 0.4
179 INT221544 Phosphorylation of Crmp1 1 0.29 1.33 0.4
180 INT343628 Regulation of Positive_regulation of Cav2 1 0.19 0 0.4
181 INT41125 Positive_regulation of Localization of Rb1 2 0.38 0.78 0.39
182 INT41126 Localization of Rb1 2 0.61 0.78 0.39
183 INT343972 Negative_regulation of Binding of SNCA 1 0.36 0.2 0.39
184 INT136180 Binding of MTOR 9 0.35 5.01 0.38
185 INT156120 Localization of Arrb1 1 0.00 0 0.38
186 INT292053 Regulation of Localization of Csnk1a1 1 0.34 0.51 0.38
187 INT228668 Positive_regulation of Localization of Mtor 1 0.39 0.62 0.38
188 INT156119 Positive_regulation of Localization of Arrb1 1 0.00 0 0.38
189 INT114740 Binding of GRB2 8 0.36 2.24 0.37
190 INT156201 Negative_regulation of Gene_expression of MTOR 6 0.58 7.7 0.36
191 INT169628 Binding of SNCA 4 0.47 3.53 0.36
192 INT139450 Binding of IGF2R 3 0.19 1.75 0.36
193 INT168766 Positive_regulation of Binding of Pik3r1 3 0.21 1.54 0.35
194 INT105934 Gene_expression of APTX 1 0.00 0 0.35
195 INT196925 Positive_regulation of Gene_expression of Rb1 4 0.45 3.16 0.33
196 INT169918 Negative_regulation of Phosphorylation of Rb1 8 0.37 6.64 0.32
197 INT191211 Gene_expression of GRB2 5 0.62 0.96 0.32
198 INT249123 Binding of Mtor 9 0.36 0.57 0.3
199 INT197599 Transcription of Rb1 4 0.63 0.87 0.3
200 INT212985 Negative_regulation of Positive_regulation of Pik3r1 3 0.19 3.28 0.3
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