GO:0051233

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Name spindle midzone
Categary Component
Go Slim No
Go Link GO:0051233
Unique Molecular Interactions 219
Total Molecular Interactions 299
Total Single Events 3038
Pain Genes Associated 12

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for spindle midzone. They are ordered first by their pain relevance and then by number of times they were reported for spindle midzone. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT191618 Binding of App and Nf1 1 0.35 3.77 1.65
2 INT266406 Binding of APP and Ager 1 0.00 2.34 1.57
3 INT93781 Racgap1 Positive_regulation of Positive_regulation of Gnptab 1 0.02 0.07 1.49
4 INT93782 Racgap1 Positive_regulation of Rgs9 1 0.55 0.07 1.49
5 INT93783 Racgap1 Positive_regulation of Gnptab 1 0.02 0.07 1.49
6 INT70288 Negative_regulation of Atxn2l Positive_regulation of Racgap1 1 0.02 0.3 1.19
7 INT120205 Binding of App and Ern1 1 0.05 2.55 1.18
8 INT70289 Atxn2l Positive_regulation of Racgap1 1 0.04 0.29 1.15
9 INT168529 APP Regulation of FSIP1 2 0.65 2.26 1.07
10 INT221747 Gtf3a Positive_regulation of Positive_regulation of Racgap1 1 0.00 0.33 1
11 INT65462 Bri3 Negative_regulation of Racgap1 1 0.02 0.39 0.93
12 INT159996 Prkcg Regulation of Gene_expression of App 1 0.42 0.32 0.92
13 INT159993 App Regulation of Gene_expression of Bace1 1 0.46 0.32 0.92
14 INT159994 App Regulation of Gene_expression of Prkcg 1 0.42 0.32 0.92
15 INT167431 Binding of APP and MYO1C 1 0.23 1.38 0.83
16 INT107917 RETNLB Positive_regulation of Gene_expression of App 1 0.01 1.2 0.79
17 INT116803 Phosphorylation of Camk2b Positive_regulation of Camk4 1 0.03 0 0.76
18 INT116805 Phosphorylation of Camk2b Positive_regulation of Camk2a 1 0.07 0 0.76
19 INT99818 IFNG Positive_regulation of Gene_expression of APP 1 0.04 0.82 0.7
20 INT278077 Binding of BPHL and AURKC 1 0.16 4.29 0.69
21 INT2700 Binding of App and Cpe 1 0.00 0 0.63
22 INT333544 CTSB Regulation of Protein_catabolism of APP 1 0.01 0.53 0.62
23 INT118083 Aip Negative_regulation of Phosphorylation of APP 1 0.00 0.75 0.62
24 INT333543 CTSB Regulation of APP 1 0.01 0.53 0.62
25 INT84771 Positive_regulation of Binding of App and Pag1 1 0.17 0.9 0.62
26 INT120203 Binding of App and Il1 1 0.17 1.28 0.59
27 INT120204 Binding of App and Il1f5 1 0.09 1.28 0.59
28 INT84770 Binding of App and Pag1 1 0.13 0.89 0.57
29 INT167618 Rho Regulation of App 1 0.17 0.88 0.55
30 INT167620 Rock2 Regulation of App 1 0.13 0.87 0.55
31 INT118082 APP Positive_regulation of Casp3 1 0.00 0.5 0.54
32 INT204494 Binding of App and Fmr1 1 0.54 4.39 0.54
33 INT97949 Negative_regulation of NRP2 Negative_regulation of Positive_regulation of CDC42 1 0.06 0.72 0.51
34 INT97953 ST3GAL3 Positive_regulation of CDC42 1 0.09 0.7 0.5
35 INT330107 Racgap1 Regulation of Positive_regulation of Nox3 1 0.01 0.87 0.49
36 INT145260 Binding of CLU and App 1 0.00 0.74 0.46
37 INT330108 Racgap1 Positive_regulation of Cybb 1 0.03 0.86 0.46
38 INT177794 BUB1B Positive_regulation of Gene_expression of ASNS 1 0.11 0.77 0.46
39 INT177781 BUB1B Positive_regulation of ATF4 1 0.07 0.76 0.46
40 INT177780 BUB1B Positive_regulation of ASNS 1 0.05 0.76 0.46
41 INT177787 BUB1B Positive_regulation of MTHFD2 1 0.15 0.76 0.46
42 INT167621 Psenen Positive_regulation of App 1 0.02 0.86 0.44
43 INT167617 Bace2 Positive_regulation of App 1 0.06 0.87 0.44
44 INT167619 Protein_catabolism of Ppp2cb Positive_regulation of App 1 0.00 0.88 0.44
45 INT191610 Binding of App and Drd3 1 0.20 0.7 0.42
46 INT247599 Tlr4 Positive_regulation of Gene_expression of App 1 0.17 0.39 0.42
47 INT137834 Binding of CAMK2B and CTS 1 0.05 1.38 0.42
48 INT139873 Negative_regulation of CTSB Negative_regulation of Gene_expression of App 1 0.00 0.8 0.41
49 INT330110 Racgap1 Regulation of Gene_expression of Ros1 1 0.00 1.12 0.41
50 INT139874 CTSB Negative_regulation of Gene_expression of App 1 0.00 0.8 0.41
51 INT79577 APP Negative_regulation of PENK 1 0.12 0.35 0.4
52 INT78121 Positive_regulation of Binding of App and 20S 1 0.23 0.61 0.4
53 INT78122 Binding of App and 20S 1 0.16 0.61 0.4
54 INT323967 Il6 Positive_regulation of Gene_expression of App 1 0.10 0.86 0.38
55 INT78854 APP Positive_regulation of Localization of IL6 1 0.14 0.79 0.37
56 INT71925 Binding of Ptprs and Positive_regulation of Racgap1 1 0.10 0 0.35
57 INT71924 Ptprs Positive_regulation of Racgap1 1 0.10 0 0.35
58 INT330106 Racgap1 Positive_regulation of Positive_regulation of Mapk8 1 0.01 1.32 0.35
59 INT124376 Prodh2 Positive_regulation of App 1 0.00 0.66 0.33
60 INT124379 Prodh2 Positive_regulation of Localization of App 1 0.00 0.66 0.33
61 INT308667 Binding of Chrm1 and Positive_regulation of Binding of App 1 0.04 1.14 0.32
62 INT330109 Binding of Racgap1 and Rac1 1 0.03 1.22 0.32
63 INT147434 Psenen Positive_regulation of APP 1 0.01 0.58 0.32
64 INT285567 Binding of IL1B and Cdc42 1 0.03 0.77 0.31
65 INT68977 App Positive_regulation of Localization of Mmp9 1 0.05 0.38 0.3
66 INT135095 Negative_regulation of CTSB Negative_regulation of APP 1 0.00 0.74 0.3
67 INT319220 FSIP1 Regulation of APP 1 0.29 1.46 0.29
68 INT79592 Binding of APP and Reg1 1 0.01 0.16 0.27
69 INT25946 Regulation of Binding of Penk and App 1 0.18 0.19 0.27
70 INT269490 Binding of Racgap1 and HHIP 1 0.00 0 0.27
71 INT25944 Binding of Penk and App 1 0.15 0.19 0.27
72 INT356094 Binding of App and Tg 1 0.08 0.12 0.26
73 INT139980 Negative_regulation of CTSB Negative_regulation of Gene_expression of APP 1 0.15 0.7 0.26
74 INT139981 CTSB Negative_regulation of Gene_expression of APP 1 0.11 0.7 0.26
75 INT39010 App Negative_regulation of Gene_expression of Gnrh1 1 0.05 0.07 0.26
76 INT114244 Cpox Negative_regulation of Gene_expression of APP 1 0.00 0.7 0.25
77 INT191619 Binding of App and Flna 1 0.04 0.18 0.24
78 INT292565 MAP3K5 Positive_regulation of Positive_regulation of CDC42 1 0.02 0 0.23
79 INT70082 Binding of APP and TGM1 1 0.00 1.22 0.22
80 INT319971 App Regulation of Enpp1 1 0.02 0.72 0.21
81 INT71923 Ptprs Regulation of Racgap1 1 0.09 0 0.21
82 INT146687 Regulation of Binding of App and Aph1a 1 0.16 0.58 0.19
83 INT146686 Binding of App and Aph1a 1 0.14 0.58 0.19
84 INT231836 Pcdh8 Regulation of Positive_regulation of Racgap1 1 0.00 0.58 0.18
85 INT231866 INCENP Regulation of Positive_regulation of Racgap1 1 0.00 0.58 0.18
86 INT25945 Plat Regulation of App 1 0.15 0.25 0.17
87 INT25947 Plat Regulation of Transcription of App 1 0.15 0.25 0.17
88 INT319974 App Negative_regulation of Enpp1 1 0.02 0.58 0.16
89 INT204478 Fmr1 Regulation of Gene_expression of App 1 0.50 1.44 0.16
90 INT201744 Ngf Regulation of Transcription of App 1 0.06 0.39 0.15
91 INT201728 Ntrk1 Regulation of Transcription of App 1 0.03 0.39 0.15
92 INT354823 IFNA1 Positive_regulation of Racgap1 1 0.00 1.4 0.15
93 INT319972 App Negative_regulation of Gene_expression of Enpp1 1 0.02 1.87 0.15
94 INT286476 Binding of App and Itm2b 1 0.47 5.24 0.14
95 INT94763 PSEN2 Regulation of Positive_regulation of App 1 0.11 0.72 0.14
96 INT139849 Binding of App and Bace1 7 0.41 0.85 0.13
97 INT184953 Binding of CDC6 and PCNA 1 0.05 0.19 0.13
98 INT204489 Fmr1 Regulation of App 1 0.50 1.71 0.13
99 INT220622 App Positive_regulation of Rip 2 0.14 0.24 0.12
100 INT269491 Racgap1 Negative_regulation of RAB5A 1 0.01 0 0.12
101 INT308660 Binding of Ager and App 1 0.08 1.22 0.12
102 INT70084 Negative_regulation of Binding of APP and TGM1 1 0.00 0.61 0.11
103 INT70083 TGM1 Positive_regulation of Binding of APP 1 0.00 0.61 0.11
104 INT123101 Binding of APP and Ache 1 0.07 0.32 0.11
105 INT287267 EGF Positive_regulation of CDC42 1 0.12 0.16 0.11
106 INT204477 Binding of App and Scn10a 1 0.17 0.36 0.1
107 INT139847 Binding of App and Bace2 1 0.03 0.16 0.1
108 INT139850 Binding of MBTPS1 and App 1 0.00 0.16 0.1
109 INT193963 App Regulation of Gene_expression of Ps 1 0.06 0.93 0.09
110 INT356112 Binding of App and Apba1 1 0.24 0.29 0.09
111 INT262701 App Positive_regulation of Aplp2 1 0.12 0.25 0.09
112 INT262705 App Positive_regulation of Aplp1 1 0.13 0.25 0.09
113 INT124036 Binding of App and Dnahc8 1 0.03 0.14 0.09
114 INT202407 Binding of Osm and Racgap1 1 0.04 0.13 0.09
115 INT202399 Binding of Mapk14 and Racgap1 1 0.07 0.13 0.09
116 INT205135 Binding of APOE and APP 1 0.05 0.35 0.08
117 INT193959 Psen1 Regulation of App 1 0.40 0.58 0.08
118 INT204487 Positive_regulation of Fmr1 Regulation of Gene_expression of App 1 0.30 0.8 0.08
119 INT193954 Binding of App and Psen1 3 0.38 0.88 0.06
120 INT198934 Binding of App and Lrp1b 2 0.27 1.62 0.05
121 INT221470 Binding of Racgap1 and Camkk2 1 0.00 0.06 0.05
122 INT288099 Binding of APP and App 1 0.01 1.04 0.05
123 INT356086 Negative_regulation of Binding of App and Lrp1b 1 0.30 1.42 0.05
124 INT221469 Binding of Racgap1 and Rrad 1 0.02 0.06 0.05
125 INT356110 Binding of App and Slc5a7 1 0.02 0.25 0.05
126 INT236009 HIST2H2AA3 Positive_regulation of Protein_catabolism of APP 1 0.02 0.19 0.04
127 INT236015 HIST2H2AA3 Positive_regulation of Gene_expression of APP 1 0.02 0.95 0.04
128 INT162753 Binding of APP and Slc30a2 1 0.00 1.25 0.04
129 INT319973 App Regulation of Gene_expression of Mapk12 1 0.02 0.98 0.04
130 INT162754 Negative_regulation of Binding of APP and Slc30a2 1 0.00 1.26 0.04
131 INT215240 Binding of Myo1f and Racgap1 1 0.01 0.77 0.04
132 INT215244 Binding of Racgap1 and Mlph 1 0.04 0.76 0.04
133 INT356101 App Regulation of Negative_regulation of Psen1 1 0.23 0.31 0.04
134 INT198921 Binding of App and Lrp1 3 0.32 2.7 0.03
135 INT356102 Negative_regulation of Binding of App and Lrp1 1 0.32 0.71 0.03
136 INT237090 Binding of App and Bnip3l 1 0.18 1.66 0.03
137 INT181083 Binding of Akt1 and Cdc42 1 0.00 0.79 0.03
138 INT230137 OSBP Regulation of APP 1 0.59 0.15 0.03
139 INT356097 Binding of App and Apba3 1 0.12 0.12 0.03
140 INT270432 Lhb Positive_regulation of APP 1 0.03 0.51 0.03
141 INT241459 Gart Positive_regulation of Racgap1 1 0.01 0 0.03
142 INT356090 Binding of Apba2 and App 1 0.00 0.12 0.03
143 INT270431 Gnrh1 Positive_regulation of APP 1 0.06 0.51 0.03
144 INT183896 Gene_expression of CAV1 Negative_regulation of Positive_regulation of Racgap1 1 0.01 0.64 0.03
145 INT220628 Gene_expression of Gga1 Positive_regulation of App 2 0.22 0 0
146 INT220625 Negative_regulation of Binding of App and Bace1 1 0.44 0.09 0
147 INT295702 PTGER2 Positive_regulation of Racgap1 1 0.05 0.22 0
148 INT295701 Positive_regulation of Binding of RAC1 and Racgap1 1 0.28 0.16 0
149 INT356108 App Positive_regulation of Positive_regulation of Lrp1 1 0.43 0.52 0
150 INT333770 Bace1 Regulation of Gene_expression of App 1 0.57 0 0
151 INT295704 Positive_regulation of Binding of RHOA and Racgap1 1 0.15 0.16 0
152 INT326163 Binding of Racgap1 and RAB12 1 0.00 0.68 0
153 INT183895 CAV1 Regulation of Positive_regulation of Racgap1 1 0.01 0.37 0
154 INT204493 App Negative_regulation of Scn10a 1 0.20 0.74 0
155 INT236013 HIST2H2AA3 Regulation of Gene_expression of APP 1 0.01 0 0
156 INT204499 App Regulation of Fmr1 1 0.50 0.59 0
157 INT204492 Negative_regulation of Binding of App and Fmr1 1 0.42 0.28 0
158 INT356083 Binding of App and Notch1 1 0.02 0.2 0
159 INT271996 Binding of Plk1 and Tsc1 1 0.09 0.32 0
160 INT234996 Ctnnd1 Positive_regulation of CDC42 1 0.01 0.07 0
161 INT356095 Lrp1 Positive_regulation of App 1 0.37 0.53 0
162 INT204502 Binding of App and RNPC3 1 0.01 0.09 0
163 INT356091 Lrp1 Positive_regulation of Positive_regulation of App 1 0.43 0.52 0
164 INT194333 Binding of MFN2 and Racgap1 1 0.01 0.38 0
165 INT204481 App Negative_regulation of Positive_regulation of Scn10a 1 0.20 0.74 0
166 INT356100 Binding of Apbb1 and App 1 0.14 0.43 0
167 INT249148 Binding of Was and Racgap1 1 0.03 0.18 0
168 INT356087 Binding of App and Ncstn 1 0.17 0.07 0
169 INT230140 Gene_expression of OSBP Regulation of Localization of APP 1 0.30 0.06 0
170 INT295700 Binding of RAC1 and Racgap1 1 0.21 0.16 0
171 INT198933 Binding of Apoe and App 1 0.33 0.19 0
172 INT183897 Binding of RHOC and Racgap1 1 0.01 0.2 0
173 INT249149 Binding of Cdc42 and Was 1 0.08 0.18 0
174 INT198927 Lrp1 Regulation of App 1 0.14 0.42 0
175 INT204482 Fmr1 Negative_regulation of App 1 0.42 0.74 0
176 INT334643 Binding of APP and HM13 1 0.02 0 0
177 INT356118 Binding of SORL1 and App 1 0.41 0.43 0
178 INT230146 Binding of APP and SORL1 1 0.20 0.17 0
179 INT356109 Rab6a Regulation of App 1 0.14 0.05 0
180 INT180123 Egfl7 Positive_regulation of App 1 0.02 0.07 0
181 INT356106 Gene_expression of Pld1 Positive_regulation of App 1 0.29 0.21 0
182 INT271997 Binding of Cdk1 and Plk1 1 0.03 0.3 0
183 INT225629 APP Positive_regulation of Positive_regulation of nr 1 0.01 0.08 0
184 INT217396 Binding of Abca1 and App 1 0.26 0.83 0
185 INT262708 Bace1 Positive_regulation of Gene_expression of App 1 0.44 2.82 0
186 INT198915 Binding of App and Lrp8 1 0.24 0.17 0
187 INT230139 OSBP Regulation of Phosphorylation of APP 1 0.50 0 0
188 INT142955 Positive_regulation of Binding of APP and BACE1 1 0.48 0.5 0
189 INT262713 App Regulation of Transcription of Bace1 1 0.45 0.31 0
190 INT198925 Binding of App and Ldlr 1 0.14 0.15 0
191 INT295703 Binding of RHOA and Racgap1 1 0.11 0.16 0
192 INT333773 Bace1 Regulation of App 1 0.25 0 0
193 INT230143 OSBP Regulation of Gene_expression of APP 1 0.50 0.1 0
194 INT142954 Binding of APP and BACE1 1 0.37 0.5 0
195 INT204491 Ass1 Positive_regulation of App 1 0.01 0.43 0
196 INT234221 Negative_regulation of PSEN1 Negative_regulation of Gene_expression of APP 1 0.33 0.32 0
197 INT249822 Foxm1 Positive_regulation of Transcription of Plk1 1 0.50 0.12 0
198 INT50104 Bche Regulation of Localization of App 1 0.43 0.2 0
199 INT356104 Positive_regulation of Binding of App and Lrp1 1 0.40 0.52 0
200 INT230151 OSBP Regulation of Localization of APP 1 0.50 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for spindle midzone. They are ordered first by their pain relevance and then by number of times they were reported in spindle midzone. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT65500 Gene_expression of App 605 0.78 429.94 98.31
2 INT29743 Negative_regulation of App 91 0.59 65.56 31.26
3 INT47712 Positive_regulation of App 135 0.69 101.38 28.94
4 INT89662 Positive_regulation of Gene_expression of App 169 0.70 133.36 25.62
5 INT44954 Gene_expression of APP 191 0.78 105.86 23.9
6 INT11625 Localization of App 98 0.78 55.46 20.86
7 INT16794 Binding of App 103 0.48 64.87 19.79
8 INT65502 Regulation of App 77 0.62 52.05 19.44
9 INT12725 Positive_regulation of Racgap1 66 0.68 32.74 19.29
10 INT23657 Positive_regulation of APP 64 0.70 39.76 16.68
11 INT54052 Gene_expression of App 33 0.78 25.08 14.7
12 INT29745 Binding of APP 47 0.48 26.49 12.4
13 INT107916 Protein_catabolism of App 114 1.00 66.71 12.38
14 INT65501 Regulation of Gene_expression of App 56 0.62 32.51 11.48
15 INT98789 Negative_regulation of Gene_expression of App 54 0.58 40.27 11.15
16 INT41569 Regulation of APP 32 0.62 17.15 9.4
17 INT60285 Negative_regulation of Racgap1 27 0.56 21.71 8.14
18 INT56031 Positive_regulation of App 25 0.69 13.46 7.37
19 INT84932 Negative_regulation of APP 29 0.57 28.45 7.2
20 INT185879 Gene_expression of CDC6 9 0.39 5.18 6.46
21 INT107173 Phosphorylation of App 20 0.82 12.64 5.3
22 INT99823 Positive_regulation of Gene_expression of APP 31 0.70 21.52 5.09
23 INT115816 Protein_catabolism of APP 35 0.99 20.14 5.06
24 INT131692 Negative_regulation of Localization of App 9 0.53 4.69 4.82
25 INT78116 Positive_regulation of Gene_expression of App 12 0.70 10.78 4.52
26 INT58003 Localization of APP 32 0.80 13.75 4.2
27 INT99821 Negative_regulation of Gene_expression of APP 20 0.42 15.21 3.94
28 INT80347 Positive_regulation of Camk2b 2 0.69 0.33 3.67
29 INT11627 Positive_regulation of Localization of App 14 0.62 6.27 3.64
30 INT99819 Negative_regulation of Positive_regulation of APP 6 0.58 4.41 3.64
31 INT70089 Negative_regulation of Binding of APP 7 0.59 6.45 3.44
32 INT80345 Gene_expression of Camk2b 3 0.77 0.5 3.44
33 INT52839 Regulation of Racgap1 14 0.25 9.46 3.37
34 INT108773 Negative_regulation of Binding of App 10 0.42 7.26 2.96
35 INT54055 Regulation of Gene_expression of App 7 0.62 4.04 2.93
36 INT80346 Negative_regulation of Camk2b 3 0.58 0.58 2.81
37 INT178772 Transcription of App 17 0.70 10.79 2.79
38 INT147429 Negative_regulation of Positive_regulation of App 8 0.40 8.73 2.78
39 INT54054 Binding of App 4 0.48 10.89 2.78
40 INT70286 Negative_regulation of Positive_regulation of Racgap1 2 0.43 3.78 2.42
41 INT162513 Regulation of Protein_catabolism of APP 5 0.51 1.79 2.36
42 INT54515 Positive_regulation of Positive_regulation of Racgap1 6 0.12 2.33 2.34
43 INT11626 Regulation of Localization of App 4 0.45 1.51 2.34
44 INT70283 Gene_expression of Racgap1 19 0.44 9.64 2.33
45 INT56030 Regulation of App 8 0.62 4.06 2.32
46 INT65459 Binding of Racgap1 9 0.07 4.57 2.28
47 INT102908 Phosphorylation of Camk2b 2 0.62 0.42 2.17
48 INT124772 Regulation of Binding of App 6 0.45 4.92 2.09
49 INT39008 Localization of App 13 0.77 9.07 2.05
50 INT142774 Regulation of Phosphorylation of App 1 0.59 2.27 1.93
51 INT306836 Negative_regulation of Gene_expression of CDC6 1 0.19 1.28 1.88
52 INT236867 Gene_expression of AURKC 6 0.55 31.96 1.86
53 INT121117 Regulation of Protein_catabolism of App 10 0.62 6.41 1.78
54 INT107915 Regulation of Negative_regulation of App 6 0.45 4.47 1.76
55 INT133863 Positive_regulation of Protein_catabolism of App 12 0.59 7.53 1.52
56 INT306875 Localization of CDC6 1 0.34 1.51 1.52
57 INT58004 Positive_regulation of Localization of APP 5 0.46 2.1 1.5
58 INT236868 Negative_regulation of AURKC 3 0.48 12.2 1.46
59 INT25943 Transcription of App 5 0.53 1.79 1.44
60 INT125796 Regulation of Gene_expression of APP 8 0.59 5.95 1.41
61 INT129700 Regulation of Positive_regulation of App 3 0.43 1.86 1.41
62 INT141529 Regulation of Positive_regulation of APP 3 0.44 0.31 1.34
63 INT219492 Negative_regulation of CDC6 2 0.20 1.74 1.31
64 INT103488 Positive_regulation of Localization of App 5 0.50 3.05 1.28
65 INT97955 Positive_regulation of CDC42 8 0.49 2.47 1.19
66 INT100137 Positive_regulation of Negative_regulation of App 2 0.41 1.26 1.16
67 INT135899 Regulation of Binding of APP 3 0.45 1.22 1.14
68 INT80341 Regulation of Gene_expression of Camk2b 1 0.61 0.08 1.08
69 INT39009 Negative_regulation of App 6 0.38 3.37 1.07
70 INT116801 Negative_regulation of Positive_regulation of Camk2b 1 0.29 0.1 1.02
71 INT306847 Positive_regulation of Gene_expression of CDC6 1 0.23 0.16 0.99
72 INT184992 Positive_regulation of CDC6 2 0.28 0.7 0.96
73 INT306882 Transcription of CDC6 1 0.24 0.57 0.92
74 INT161682 Positive_regulation of Cdc42 8 0.53 4.55 0.9
75 INT167607 Positive_regulation of Binding of App 8 0.50 2.97 0.86
76 INT162514 Positive_regulation of Regulation of APP 1 0.41 0.37 0.86
77 INT99375 Positive_regulation of Binding of APP 3 0.61 1.63 0.83
78 INT236871 Binding of AURKC 2 0.39 8.53 0.83
79 INT118078 Phosphorylation of APP 10 0.79 2.5 0.76
80 INT99820 Negative_regulation of Localization of APP 2 0.37 0.75 0.76
81 INT330076 Regulation of Positive_regulation of Racgap1 1 0.04 1.98 0.73
82 INT112208 Negative_regulation of Gene_expression of App 4 0.59 1.88 0.68
83 INT25942 Regulation of Transcription of App 3 0.27 0.95 0.68
84 INT141528 Regulation of Localization of APP 2 0.52 0.4 0.67
85 INT61147 Protein_catabolism of App 3 0.60 3.76 0.63
86 INT102906 Positive_regulation of Gene_expression of Camk2b 1 0.68 0.43 0.63
87 INT102909 Positive_regulation of Phosphorylation of Camk2b 1 0.46 0.43 0.63
88 INT289327 Regulation of Negative_regulation of Racgap1 2 0.05 2.09 0.62
89 INT118077 Negative_regulation of Phosphorylation of APP 1 0.07 0.74 0.61
90 INT180107 Regulation of Cdc42 3 0.16 0.18 0.6
91 INT142112 Regulation of Regulation of App 3 0.39 2.46 0.59
92 INT200956 Negative_regulation of CAMK2B 1 0.37 0.93 0.56
93 INT225462 Positive_regulation of Positive_regulation of APP 3 0.44 1.41 0.55
94 INT97956 Negative_regulation of CDC42 3 0.27 1.58 0.55
95 INT236865 Positive_regulation of AURKC 3 0.57 18.45 0.54
96 INT78117 Positive_regulation of Positive_regulation of App 4 0.48 2.6 0.51
97 INT177869 Gene_expression of BUB1B 2 0.65 2.11 0.45
98 INT177866 Negative_regulation of BUB1B 1 0.32 1.23 0.45
99 INT177845 Negative_regulation of Gene_expression of BUB1B 1 0.23 0.75 0.45
100 INT167614 Positive_regulation of Protein_catabolism of App 1 0.30 0.88 0.44
101 INT199077 Localization of Racgap1 7 0.73 2.43 0.42
102 INT137835 Binding of CAMK2B 1 0.08 1.38 0.42
103 INT288080 Regulation of Gene_expression of Racgap1 3 0.04 3.42 0.41
104 INT236870 Positive_regulation of Gene_expression of AURKC 3 0.41 10.18 0.35
105 INT330074 Negative_regulation of Binding of Racgap1 1 0.03 1.47 0.35
106 INT330075 Negative_regulation of Transcription of Racgap1 1 0.03 1.05 0.33
107 INT330077 Transcription of Racgap1 1 0.05 1.04 0.33
108 INT54056 Negative_regulation of Binding of App 2 0.37 0.99 0.32
109 INT178773 Positive_regulation of Regulation of App 2 0.49 1.01 0.32
110 INT178774 Positive_regulation of Transcription of App 2 0.49 1.17 0.31
111 INT270418 Negative_regulation of Negative_regulation of Racgap1 1 0.02 0.53 0.31
112 INT184987 Regulation of CDC6 2 0.12 0.27 0.25
113 INT183881 Localization of CDC42 3 0.49 1.92 0.23
114 INT183876 Regulation of CDC42 3 0.30 1.94 0.19
115 INT180104 Positive_regulation of Phosphorylation of App 2 0.54 0.87 0.16
116 INT197290 Gene_expression of Cdc42 9 0.35 2.52 0.15
117 INT286326 Regulation of Transcription of App 3 0.45 0.26 0.15
118 INT200987 Transcription of CAMK2B 2 0.44 0.2 0.14
119 INT200978 Regulation of Transcription of CAMK2B 1 0.29 0.15 0.14
120 INT185019 Binding of CDC6 2 0.21 0.31 0.13
121 INT69045 Negative_regulation of Positive_regulation of App 1 0.05 0.28 0.13
122 INT184998 Negative_regulation of Binding of CDC6 1 0.11 0.19 0.13
123 INT206133 Binding of CDC42 3 0.25 0.8 0.12
124 INT142958 Positive_regulation of Protein_catabolism of APP 3 0.55 2.04 0.1
125 INT236878 Regulation of Gene_expression of AURKC 3 0.15 2.33 0.09
126 INT236874 Regulation of AURKC 3 0.37 2.83 0.09
127 INT197282 Positive_regulation of Gene_expression of Cdc42 3 0.26 0.12 0.08
128 INT39007 Negative_regulation of Localization of App 3 0.10 0.94 0.08
129 INT206169 Gene_expression of CDC42 2 0.26 1.05 0.05
130 INT206167 Positive_regulation of Gene_expression of CDC42 1 0.08 0.05 0.05
131 INT288079 Positive_regulation of Gene_expression of Racgap1 1 0.06 0.74 0.04
132 INT180116 Negative_regulation of Transcription of App 1 0.38 0 0.04
133 INT206049 Negative_regulation of Localization of Racgap1 1 0.01 0.12 0.04
134 INT182830 Negative_regulation of Protein_catabolism of APP 2 0.35 2.09 0.03
135 INT255657 Negative_regulation of Protein_catabolism of App 1 0.20 1.07 0.03
136 INT351386 Negative_regulation of Phosphorylation of App 1 0.42 0.82 0.03
137 INT237226 Gene_expression of Plk1 3 0.59 0.78 0
138 INT50103 Regulation of Localization of App 2 0.26 0.2 0
139 INT234255 Transcription of APP 2 0.49 0.98 0
140 INT236866 Localization of AURKC 2 0.61 2.22 0
141 INT254795 Negative_regulation of Cdc42 2 0.12 1.53 0
142 INT244607 Gene_expression of CAMK2B 2 0.23 0.23 0
143 INT249774 Positive_regulation of Plk1 2 0.41 0.25 0
144 INT270614 Localization of Cdc42 1 0.55 0.95 0
145 INT230109 Positive_regulation of Gene_expression of BUB1B 1 0.42 0.65 0
146 INT286323 Negative_regulation of Protein_catabolism of App 1 0.11 0.54 0
147 INT197294 Regulation of Gene_expression of Cdc42 1 0.13 0 0
148 INT271928 Binding of Plk1 1 0.07 0.29 0
149 INT236873 Positive_regulation of Localization of AURKC 1 0.17 1.43 0
150 INT332370 Regulation of Plk1 1 0.21 0.13 0
151 INT282269 Binding of Cdc42 1 0.08 0.33 0
152 INT332346 Phosphorylation of Plk1 1 0.62 0 0
153 INT249761 Transcription of Plk1 1 0.60 0.12 0
154 INT287281 Positive_regulation of Positive_regulation of CDC42 1 0.26 0 0
155 INT282272 Positive_regulation of Binding of Cdc42 1 0.11 0.33 0
156 INT249770 Positive_regulation of Gene_expression of Plk1 1 0.44 0.12 0
157 INT332343 Positive_regulation of Phosphorylation of Plk1 1 0.38 0 0
158 INT236037 Positive_regulation of Phosphorylation of APP 1 0.48 0.14 0
159 INT271923 Regulation of Binding of Plk1 1 0.09 0.29 0
160 INT237227 Negative_regulation of Gene_expression of Plk1 1 0.08 0.54 0
161 INT278078 Regulation of Positive_regulation of AURKC 1 0.37 2.03 0
162 INT354089 Positive_regulation of Transcription of CAMK2B 1 0.09 0.05 0
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