GO:0051247

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Name positive regulation of protein metabolic process
Categary Process
Go Slim No
Go Link GO:0051247
Unique Molecular Interactions 34
Total Molecular Interactions 44
Total Single Events 272
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of protein metabolic process. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of protein metabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT106346 Mtpn Regulation of Chat 1 0.06 0 0.52
2 INT297352 KLF2 Regulation of PPARA 1 0.12 1.31 0.35
3 INT228446 PMAIP1 Regulation of Transcription of Mtpn 1 0.00 0 0.34
4 INT137418 MAPK7 Negative_regulation of Gene_expression of TNF 1 0.01 0.63 0.28
5 INT250853 Binding of Fgf1 and Mtpn 1 0.00 0.28 0.21
6 INT256706 Binding of Hsp90b1 and Wfs1 1 0.43 5.02 0.2
7 INT137417 MAPK7 Regulation of Gene_expression of NOS3 1 0.00 0.5 0.19
8 INT186098 EGF Positive_regulation of MAP2K5 1 0.01 0.19 0.18
9 INT193553 Mtpn Positive_regulation of Ephb1 1 0.04 0.34 0.13
10 INT193551 Mtpn Positive_regulation of Gene_expression of Gdnf 1 0.02 0.34 0.13
11 INT193552 Gdnf Positive_regulation of Gene_expression of Mtpn 1 0.02 0.34 0.13
12 INT224040 Mtpn Positive_regulation of P2RY1 1 0.00 0.85 0.12
13 INT354194 Mtpn Negative_regulation of MIR524 1 0.00 0.08 0.11
14 INT156836 ETS1 Positive_regulation of Phosphorylation of MAPK7 1 0.14 0 0.1
15 INT156838 MAPK7 Positive_regulation of Phosphorylation of ETS1 1 0.13 0 0.1
16 INT156832 MAPK7 Positive_regulation of Transcription of CYP24A1 1 0.35 0 0.1
17 INT140048 Mapk7 Positive_regulation of Nfkb1 1 0.53 0.38 0.08
18 INT351983 Mtpn Positive_regulation of Gene_expression of Ifng 1 0.01 0.41 0.05
19 INT351979 Mtpn Positive_regulation of Gene_expression of Tnf 1 0.02 0.41 0.05
20 INT206619 Mtpn Positive_regulation of Igf1 1 0.04 0.17 0.05
21 INT233855 Binding of Ppara and Mapk7 1 0.09 0.9 0.05
22 INT351981 Mtpn Positive_regulation of Gene_expression of Agt 1 0.04 0.41 0.05
23 INT256707 Eif2ak3 Regulation of Gene_expression of Wfs1 1 0.10 0.78 0.03
24 INT139004 Mtpn Regulation of NFKB1 1 0.33 0.55 0
25 INT256703 Negative_regulation of Hsp90b1 Positive_regulation of Wfs1 1 0.42 0.24 0
26 INT256700 Negative_regulation of Binding of Hsp90b1 and Wfs1 1 0.52 0 0
27 INT175767 IL1B Regulation of Mtpn 1 0.00 0.06 0
28 INT337408 Binding of TCF4 and KLF4 1 0.09 0 0
29 INT225001 Binding of Mtpn and Trib3 1 0.00 0.15 0
30 INT234378 MAPK7 Positive_regulation of PPARA 1 0.21 0.05 0
31 INT256705 Binding of Wfs1 and Xbp1 1 0.19 0.39 0
32 INT256704 Xbp1 Positive_regulation of Positive_regulation of Wfs1 1 0.26 0.4 0
33 INT256702 Binding of Wfs1 and Tmed4 1 0.01 0.61 0
34 INT225020 Binding of PDGFB and Mtpn 1 0.01 0.15 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of protein metabolic process. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of protein metabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT26795 Gene_expression of Mtpn 44 0.62 27.66 8.62
2 INT50295 Regulation of Mtpn 13 0.26 7.54 3.77
3 INT133144 Localization of Mtpn 18 0.24 7.88 2.77
4 INT143841 Positive_regulation of Mtpn 17 0.17 5.46 2.68
5 INT105598 Negative_regulation of Mtpn 15 0.16 11.83 2.65
6 INT228445 Transcription of Mtpn 1 0.03 0.35 1.72
7 INT87157 Regulation of Gene_expression of Mtpn 4 0.49 0.78 1.24
8 INT139261 Positive_regulation of Gene_expression of Mtpn 8 0.05 5.95 1.22
9 INT228437 Regulation of Transcription of Mtpn 1 0.03 0.08 1.02
10 INT303716 Negative_regulation of Positive_regulation of MAPK7 1 0.14 0.86 0.66
11 INT303715 Positive_regulation of MAPK7 3 0.52 5.52 0.62
12 INT192086 Positive_regulation of Positive_regulation of Mtpn 4 0.06 0.53 0.59
13 INT172066 Binding of Mtpn 3 0.02 1.51 0.52
14 INT256860 Negative_regulation of Negative_regulation of Mtpn 2 0.16 1.31 0.5
15 INT165828 Regulation of Mapk7 2 0.24 0.19 0.39
16 INT256681 Regulation of Wfs1 8 0.43 4.72 0.36
17 INT297364 Positive_regulation of KLF2 1 0.18 1.24 0.34
18 INT137420 Gene_expression of MAPK7 4 0.59 3.22 0.33
19 INT126524 Positive_regulation of Mapk7 3 0.45 2.14 0.32
20 INT228440 Positive_regulation of Transcription of Mtpn 1 0.03 0 0.32
21 INT256682 Gene_expression of Wfs1 1 0.74 6.63 0.25
22 INT185514 Negative_regulation of Positive_regulation of Mtpn 2 0.03 0.18 0.23
23 INT210951 Positive_regulation of Localization of Mtpn 3 0.02 1.75 0.17
24 INT256696 Positive_regulation of Wfs1 1 0.66 9.14 0.17
25 INT256684 Positive_regulation of Gene_expression of Wfs1 1 0.66 3.62 0.16
26 INT225012 Regulation of Localization of Mtpn 2 0.01 0.14 0.13
27 INT140045 Positive_regulation of Positive_regulation of Mapk7 1 0.45 0.45 0.1
28 INT156851 Positive_regulation of Phosphorylation of MAPK7 1 0.32 0 0.1
29 INT156856 Phosphorylation of MAPK7 1 0.52 0 0.1
30 INT282593 Gene_expression of KLF4 8 0.61 1.09 0.09
31 INT156853 Negative_regulation of MAPK7 2 0.32 0.75 0.09
32 INT156843 Negative_regulation of Gene_expression of MAPK7 1 0.27 0 0.09
33 INT140046 Gene_expression of Mapk7 1 0.60 0.4 0.09
34 INT256675 Regulation of Gene_expression of Wfs1 1 0.43 2.33 0.09
35 INT256687 Positive_regulation of Transcription of Wfs1 1 0.44 1.95 0.09
36 INT140047 Negative_regulation of Mapk7 1 0.38 0.4 0.09
37 INT256693 Transcription of Wfs1 1 0.68 2.44 0.08
38 INT233836 Binding of Mapk7 2 0.17 0.9 0.05
39 INT282606 Positive_regulation of Gene_expression of KLF4 2 0.54 0.8 0.04
40 INT282592 Regulation of KLF4 1 0.26 0.14 0.03
41 INT294852 Negative_regulation of KLF4 2 0.20 0.49 0
42 INT201779 Phosphorylation of Mtpn 2 0.01 0.91 0
43 INT294855 Negative_regulation of Gene_expression of KLF4 1 0.13 0.49 0
44 INT256676 Regulation of Binding of Wfs1 1 0.43 0.35 0
45 INT320535 Positive_regulation of Gene_expression of MAPK7 1 0.52 2.06 0
46 INT256692 Negative_regulation of Wfs1 1 0.41 0 0
47 INT256671 Regulation of Positive_regulation of Wfs1 1 0.59 1.77 0
48 INT337469 Binding of KLF4 1 0.17 0 0
49 INT256686 Binding of Wfs1 1 0.46 0.91 0
50 INT294846 Positive_regulation of Negative_regulation of KLF4 1 0.15 0.49 0
51 INT339596 Localization of KLF4 1 0.26 0 0
52 INT256677 Regulation of Transcription of Wfs1 1 0.59 0.5 0
53 INT246769 Positive_regulation of Phosphorylation of Mtpn 1 0.01 0 0
54 INT256672 Positive_regulation of Positive_regulation of Wfs1 1 0.44 0.24 0
55 INT294861 Positive_regulation of KLF4 1 0.15 0.49 0
56 INT221828 Binding of MAPK7 1 0.11 0.7 0
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