GO:0051259

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Name protein oligomerization
Categary Process
Go Slim No
Go Link GO:0051259
Unique Molecular Interactions 385
Total Molecular Interactions 483
Total Single Events 4790
Pain Genes Associated 52

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for protein oligomerization. They are ordered first by their pain relevance and then by number of times they were reported for protein oligomerization. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT73597 Positive_regulation of BAX Positive_regulation of Casp1 1 0.06 0.69 1.28
2 INT73598 BAX Positive_regulation of Casp1 1 0.06 0.63 1.27
3 INT169768 Binding of Slc6a4 and Mir16-1 1 0.33 0 1.25
4 INT277192 SUGT1 Positive_regulation of Gene_expression of SLC6A4 1 0.01 0.86 1.04
5 INT144108 Binding of SLC6A3 and SLC6A4 1 0.12 0.64 1.03
6 INT65631 Ufm1 Positive_regulation of Kcna5 1 0.02 0 0.99
7 INT333303 Zic2 Regulation of Gene_expression of Slc6a4 1 0.60 0.47 0.91
8 INT151779 Calca Positive_regulation of Transcription of P2rx7 1 0.02 0.54 0.87
9 INT215598 Positive_regulation of P2rx7 Positive_regulation of Localization of TNF 1 0.22 1.44 0.85
10 INT243024 Binding of Dcpp1 and Slc6a4 1 0.08 0.42 0.76
11 INT243025 Dcpp1 Regulation of Slc6a4 1 0.10 0.43 0.76
12 INT169769 Mir16-1 Regulation of Slc6a4 1 0.24 0 0.74
13 INT333296 Gtf3a Regulation of Gene_expression of Slc6a4 1 0.01 0 0.74
14 INT15221 RRM1 Regulation of Localization of VIP 1 0.12 0.08 0.74
15 INT15222 RRM1 Regulation of VIP 1 0.12 0.08 0.74
16 INT128404 Mapk1 Positive_regulation of Phosphorylation of Gja1 1 0.65 0.73 0.73
17 INT205706 P2rx7 Regulation of Gene_expression of Il18 1 0.21 1.35 0.7
18 INT129919 IFNA2 Positive_regulation of Gene_expression of SLC6A4 1 0.02 0.38 0.69
19 INT74727 Binding of Slc6a4 and Hpic1 1 0.00 0.49 0.68
20 INT74728 Binding of Slc6a4 and Ptprj 1 0.01 0.48 0.68
21 INT129921 IL4 Positive_regulation of Gene_expression of SLC6A4 1 0.01 0.38 0.68
22 INT246335 Fig4 Regulation of Localization of P2rx7 1 0.01 0 0.67
23 INT205702 P2rx7 Regulation of Gene_expression of Il1 1 0.04 1.38 0.67
24 INT333305 Zic2 Positive_regulation of Transcription of Slc6a4 1 0.68 0 0.66
25 INT296793 Akt1 Positive_regulation of Gene_expression of Bax 1 0.11 0.75 0.65
26 INT296790 Tlr9 Regulation of Bax 1 0.14 0.76 0.65
27 INT296791 Positive_regulation of Akt1 Positive_regulation of Gene_expression of Bax 1 0.11 0.8 0.65
28 INT144107 Binding of SLC6A2 and SLC6A4 1 0.00 0.18 0.62
29 INT112699 Bid Regulation of Bax 1 0.25 0.51 0.61
30 INT168416 MIR146A Regulation of Irak1 1 0.24 0.99 0.59
31 INT205705 Positive_regulation of P2rx7 Positive_regulation of Gene_expression of Il6 1 0.07 1.42 0.58
32 INT333302 Zic2 Positive_regulation of Slc6a4 1 0.68 0.11 0.57
33 INT162789 Binding of TLR2 and NOD2 1 0.37 0.51 0.57
34 INT162790 Binding of TLR4 and NOD2 1 0.36 0.51 0.57
35 INT308174 Binding of TNF and P2rx7 1 0.02 0.84 0.56
36 INT144129 Prkce Positive_regulation of Phosphorylation of Gja1 1 0.42 0.48 0.55
37 INT202157 Binding of CSF1R and SLC6A4 1 0.08 0.9 0.54
38 INT185490 Atp5o Negative_regulation of Gene_expression of P2rx7 1 0.01 0.87 0.53
39 INT128431 SLC6A4 Regulation of S100A4 1 0.48 0.65 0.53
40 INT144128 Binding of Gja1 and Prkce 1 0.40 0.5 0.52
41 INT216941 P2rx7 Regulation of Ryr1 1 0.01 0.55 0.52
42 INT144130 Binding of Gja1 and Prkcg 1 0.48 0.5 0.52
43 INT47745 Binding of Slc6a4 and Htr2a 1 0.33 0.09 0.52
44 INT278122 Negative_regulation of P2rx7 Negative_regulation of Binding of P2RX7 1 0.03 0 0.51
45 INT271191 Bdnf Regulation of Slc6a4 1 0.03 0.29 0.51
46 INT235870 Bdnf Regulation of Gene_expression of Slc6a4 1 0.09 0.77 0.5
47 INT235885 Prkca Negative_regulation of Slc6a4 1 0.05 0.14 0.49
48 INT254348 Binding of ANGPT1 and TEK 1 0.04 1.72 0.48
49 INT96282 Cav2 Regulation of Positive_regulation of Gabrg1 1 0.25 0 0.48
50 INT95404 Map3k1 Positive_regulation of Phosphorylation of Ephb1 1 0.12 0.16 0.46
51 INT95408 Map3k1 Positive_regulation of Ephb1 1 0.12 0.16 0.46
52 INT238638 Gopc Negative_regulation of Gene_expression of Bax 1 0.04 0.85 0.45
53 INT113248 Olr1259 Negative_regulation of Slc6a4 1 0.00 0.23 0.44
54 INT116613 Lnpep Negative_regulation of Gene_expression of BAX 1 0.42 0.62 0.43
55 INT36743 NLRP3 Regulation of Mbp 1 0.01 0 0.43
56 INT169859 P2rx7 Regulation of Gene_expression of Grin1 1 0.17 0 0.43
57 INT116612 Lnpep Negative_regulation of BAX 1 0.42 0.62 0.42
58 INT354704 Binding of MAP3K1 and Pick1 1 0.00 0.76 0.41
59 INT339493 Binding of Irak1 and Irak3 1 0.02 0.17 0.41
60 INT191493 Binding of AGTR1 and NLRP3 2 0.03 2.35 0.39
61 INT339504 Binding of Irak1 and Tlr4 1 0.08 0.12 0.38
62 INT273617 Gene_expression of Slc6a4 Positive_regulation of Pah 1 0.02 0.93 0.38
63 INT339506 Binding of Irak1 and Traf6 1 0.03 0.12 0.37
64 INT154782 Binding of SLC6A4 and Ndst2 1 0.01 0 0.37
65 INT172213 Binding of BAX and BCL2L1 3 0.22 4.02 0.35
66 INT334632 Binding of Kcna2 and Eae1 1 0.17 0.87 0.35
67 INT205704 P2rx7 Regulation of Localization of Il18 1 0.09 0.67 0.35
68 INT155061 Stat3 Negative_regulation of Bax 1 0.22 3.71 0.34
69 INT140667 IFNG Regulation of Gene_expression of SLC6A4 1 0.40 0.41 0.34
70 INT140666 TNF Regulation of Gene_expression of SLC6A4 1 0.40 0.41 0.34
71 INT205713 Positive_regulation of P2rx7 Positive_regulation of Gene_expression of IL8 1 0.03 0.77 0.33
72 INT217025 P2rx7 Regulation of Gene_expression of Ik 1 0.00 0.25 0.33
73 INT181896 TNF Regulation of TEK 1 0.03 1.21 0.33
74 INT217024 Regulation of P2rx7 Regulation of Gene_expression of Ik 1 0.00 0.25 0.33
75 INT205703 P2rx7 Regulation of Positive_regulation of Casp1 1 0.11 0.66 0.33
76 INT205711 P2rx7 Regulation of Localization of IL8 1 0.02 0.92 0.33
77 INT263978 Binding of ADRB2 and TNFAIP3 1 0.01 0.5 0.32
78 INT255934 Tauph Positive_regulation of Map3k1 1 0.00 0.1 0.32
79 INT255946 MAPK14 Positive_regulation of Map3k1 1 0.04 0.1 0.32
80 INT145682 Binding of P2rx4 and P2rx7 2 0.25 0.36 0.31
81 INT235869 Binding of Slc6a4 and Ppp2ca 1 0.04 0.21 0.31
82 INT235877 Prkaca Regulation of Transcription of Slc6a4 1 0.06 0.13 0.31
83 INT191499 CMA1 Positive_regulation of NLRP3 1 0.02 0.42 0.3
84 INT191502 Binding of CMA1 and NLRP3 1 0.01 0.42 0.3
85 INT341777 SLC6A4 Regulation of EPHB1 1 0.02 0.96 0.3
86 INT163762 MDM2 Positive_regulation of Gene_expression of BAX 1 0.27 0.86 0.3
87 INT215789 Fig4 Positive_regulation of Localization of P2rx7 1 0.03 0.53 0.29
88 INT191501 NLRP3 Positive_regulation of ECE1 1 0.01 1.09 0.28
89 INT191505 NLRP3 Positive_regulation of Protein_catabolism of EDN1 1 0.00 1.1 0.28
90 INT324801 Positive_regulation of Binding of Chuk and Irak1 1 0.03 0.86 0.28
91 INT235874 Camk2a Positive_regulation of Slc6a4 1 0.11 0.14 0.28
92 INT324810 Binding of Chuk and Irak1 1 0.02 0.85 0.28
93 INT279265 Binding of MEFV and NLRP3 1 0.07 2.79 0.28
94 INT274932 Binding of Insrr and Map3k1 1 0.00 0 0.28
95 INT191495 NLRP3 Positive_regulation of Protein_catabolism of ECE1 1 0.01 1.09 0.28
96 INT141870 Binding of Slc2a4 and Cav1 1 0.36 0.38 0.28
97 INT274947 Binding of Map3k1 and Grip1 1 0.00 0 0.27
98 INT219156 NLRP3 Positive_regulation of IL1B 1 0.01 1.03 0.27
99 INT191497 Binding of REN and NLRP3 1 0.02 0.55 0.27
100 INT191504 CPN2 Positive_regulation of NLRP3 1 0.00 0.37 0.27
101 INT237927 BCL2 Positive_regulation of BAX 2 0.24 2.22 0.26
102 INT237919 BAX Positive_regulation of Protein_catabolism of PARP1 1 0.03 1.41 0.26
103 INT219193 Nlrp3 Positive_regulation of Positive_regulation of NLRP3 1 0.24 1.03 0.26
104 INT205701 P2rx7 Positive_regulation of Il1 1 0.04 0.8 0.25
105 INT191498 Binding of CTSG and NLRP3 1 0.07 0.37 0.25
106 INT191496 CTSG Positive_regulation of NLRP3 1 0.09 0.37 0.25
107 INT185489 Atp5o Negative_regulation of P2rx7 1 0.01 0.29 0.24
108 INT191536 Klk1c2 Positive_regulation of NLRP3 1 0.02 0.36 0.24
109 INT191537 Binding of Klk1c2 and NLRP3 1 0.02 0.36 0.24
110 INT191492 Binding of AGT and NLRP3 1 0.01 0.35 0.23
111 INT290378 NOD2 Negative_regulation of TLR2 1 0.27 0.83 0.23
112 INT290377 NOD2 Negative_regulation of Positive_regulation of TLR2 1 0.24 0.95 0.23
113 INT216911 Positive_regulation of P2rx7 Positive_regulation of Localization of Plg 1 0.02 0.13 0.23
114 INT254351 Binding of ANGPT2 and TEK 1 0.04 0.87 0.22
115 INT303029 Binding of TEK and Angpt1 1 0.26 1.82 0.22
116 INT288582 Binding of Cav1 and Kcnma1 1 0.11 0 0.22
117 INT220528 Ugt1a6b Positive_regulation of Cav1 1 0.01 1.31 0.22
118 INT329530 Malt1 Positive_regulation of Positive_regulation of Nfkb1 1 0.06 0.48 0.22
119 INT107219 Binding of P2rx7 and Atp5o 1 0.03 0.07 0.21
120 INT311613 Binding of Slc6a4 and Pten 1 0.24 0.32 0.21
121 INT216946 P2rx7 Regulation of Il10 1 0.28 0.17 0.21
122 INT107223 APEH Negative_regulation of P2rx7 1 0.00 0.13 0.21
123 INT131963 Binding of CAV2 and ATXN2 1 0.04 1.39 0.21
124 INT116469 VEGFA Positive_regulation of Amfr 1 0.01 1.39 0.21
125 INT116466 Vegfa Positive_regulation of Amfr 1 0.07 1.41 0.21
126 INT333298 Zic2 Regulation of Transcription of Slc6a4 1 0.44 0.09 0.2
127 INT121807 CACNA1A Regulation of CAV2 1 0.01 0.25 0.2
128 INT121806 PHF21A Regulation of CAV2 1 0.00 0.24 0.2
129 INT205710 CAMP Positive_regulation of P2rx7 1 0.02 0.47 0.19
130 INT343644 Grm5 Positive_regulation of Cav2 1 0.05 0 0.19
131 INT155063 Csf2 Negative_regulation of Gene_expression of Bax 1 0.27 1.46 0.18
132 INT155066 Csf2 Negative_regulation of Bax 1 0.12 1.89 0.17
133 INT349475 Regulation of Bax Regulation of Bcl2 1 0.07 1.35 0.17
134 INT220520 Ugt1a6b Positive_regulation of Gene_expression of Cav1 1 0.01 0.81 0.17
135 INT233904 NLRP3 Positive_regulation of AGT 1 0.06 0.81 0.17
136 INT155232 TXNIP Regulation of BAX 1 0.23 0.15 0.17
137 INT23165 Binding of NLRP3 and BDNF-AS 1 0.01 0.83 0.16
138 INT204791 Binding of Spg7 and Nod2 1 0.03 0.5 0.16
139 INT23164 Negative_regulation of Binding of NLRP3 and BDNF-AS 1 0.01 0.83 0.16
140 INT336891 Epo Negative_regulation of Transcription of Bax 1 0.10 0.68 0.16
141 INT204789 Binding of Tlr2 and Nod2 1 0.23 0.44 0.16
142 INT354968 Shank3 Positive_regulation of Gene_expression of Gria2 1 0.05 0 0.15
143 INT235883 Ppp2ca Regulation of Slc6a4 1 0.03 0 0.15
144 INT318305 Binding of NOD2 and NLRP3 1 0.08 1.76 0.15
145 INT349476 Bax Regulation of Bcl2 1 0.07 1.33 0.15
146 INT318306 Binding of DPEP1 and NLRP3 1 0.03 1.77 0.15
147 INT235879 Regulation of Ppp2ca Regulation of Slc6a4 1 0.03 0 0.15
148 INT130918 HMHA1 Positive_regulation of BAX 1 0.04 1.37 0.14
149 INT315030 Binding of Cav1 and Tmie 1 0.03 0.25 0.14
150 INT344710 Lipc Positive_regulation of Positive_regulation of Hdl1 1 0.04 0.87 0.14
151 INT34431 NLRP3 Positive_regulation of Localization of POMC 1 0.41 0.31 0.14
152 INT177916 PRKG1 Positive_regulation of Positive_regulation of MAP3K1 1 0.05 1.07 0.14
153 INT144027 Binding of Slc6a4 and Pdgfrb 1 0.23 0.25 0.14
154 INT315032 Binding of Cav1 and Ryr1 1 0.27 0.2 0.14
155 INT273040 Vip Regulation of Bax 1 0.23 1.69 0.13
156 INT273041 Adcyap1 Regulation of Bax 1 0.21 1.69 0.13
157 INT270827 P2rx7 Positive_regulation of Localization of Panx1 1 0.41 0.18 0.13
158 INT226192 Protein_catabolism of Bax Positive_regulation of Gtf3a 1 0.00 0.53 0.12
159 INT334257 Binding of Irak1 and Irak4 1 0.33 0.49 0.12
160 INT182481 Binding of Cav1 and Ighg2b 1 0.10 0 0.12
161 INT216945 Positive_regulation of P2rx7 Positive_regulation of Positive_regulation of Casp1 1 0.14 0.18 0.12
162 INT182482 Binding of Cav1 and Cxcl16 1 0.07 0 0.12
163 INT280488 Bdnf Positive_regulation of Gene_expression of Map3k1 1 0.01 1.49 0.11
164 INT311871 Cav1 Regulation of Mch 1 0.01 0.24 0.11
165 INT285030 Binding of Bax and Slc25a4 1 0.03 0.84 0.11
166 INT74504 Binding of P2rx7 and Rp2 1 0.02 0.19 0.11
167 INT219152 NLRP3 Positive_regulation of Positive_regulation of CASP1 1 0.02 0.83 0.1
168 INT265890 BCL2 Regulation of Gene_expression of BAX 1 0.04 1.08 0.1
169 INT265889 BAX Regulation of Gene_expression of BAD 1 0.06 1.08 0.1
170 INT220517 Negative_regulation of Ugt1a6b Positive_regulation of Cav1 1 0.01 0.35 0.1
171 INT310743 TP53 Regulation of BAX 1 0.09 1.11 0.1
172 INT339498 Binding of Il1rap and Positive_regulation of Irak1 1 0.01 0 0.1
173 INT334266 Binding of Irak1 and Myd88 2 0.35 0.16 0.09
174 INT205708 Binding of Icam1 and P2rx7 1 0.08 1.03 0.09
175 INT92389 ALK Positive_regulation of Gene_expression of Map3k1 1 0.01 1.14 0.09
176 INT334268 Irak4 Positive_regulation of Irak1 1 0.47 0.37 0.09
177 INT302977 Binding of Cav1 and Smpd2 1 0.08 0.71 0.09
178 INT252421 Gja1 Regulation of P2ry1 1 0.00 0.28 0.09
179 INT232559 Map3k1 Positive_regulation of Esr1 1 0.19 0.26 0.09
180 INT217036 IRF6 Positive_regulation of Gene_expression of P2rx7 1 0.02 0 0.09
181 INT270824 Binding of P2rx7 and Panx1 1 0.34 0.15 0.09
182 INT180443 Rhoa Regulation of Negative_regulation of Mlc1 1 0.04 0 0.09
183 INT220511 Cav1 Negative_regulation of Transcription of Ccnd1 1 0.03 0.83 0.09
184 INT335771 MIR155 Regulation of IRAK1 1 0.04 0.29 0.09
185 INT334255 Irak4 Positive_regulation of Phosphorylation of Irak1 1 0.32 0.38 0.09
186 INT304464 Binding of P2rx7 and P2rx6 1 0.05 0 0.09
187 INT233907 Positive_regulation of Binding of AGTR2 and NLRP3 1 0.01 1.09 0.08
188 INT354962 Gene_expression of Shank3 Positive_regulation of Gusb 1 0.10 0.45 0.08
189 INT307666 Binding of Pmp22 and Gjb1 1 0.31 0.38 0.08
190 INT233906 Binding of AGTR2 and NLRP3 1 0.01 1.09 0.08
191 INT243156 Positive_regulation of P2rx7 Positive_regulation of NOS1 1 0.00 0.08 0.08
192 INT309159 Binding of Cav1 and Positive_regulation of Localization of Esr1 1 0.04 0 0.08
193 INT188007 NLRP3 Regulation of Binding of TP53BP1 1 0.28 0.62 0.08
194 INT249465 Positive_regulation of Slc6a4 Positive_regulation of Gene_expression of Bdnf 1 0.31 0.3 0.08
195 INT270829 P2rx7 Positive_regulation of Panx1 1 0.66 0.08 0.08
196 INT340420 Hmmr Regulation of P2rx7 1 0.01 1.12 0.08
197 INT249466 Slc6a4 Positive_regulation of Phosphorylation of Creb1 1 0.09 0.36 0.07
198 INT285032 Bnip3 Positive_regulation of Bax 1 0.28 0.77 0.07
199 INT340401 Positive_regulation of Bax Positive_regulation of Binding of Hrk 1 0.01 0.79 0.07
200 INT270835 Positive_regulation of P2rx7 Positive_regulation of Localization of DPEP1 1 0.04 0.08 0.07

Single Events

The table below shows the top 100 pain related interactions that have been reported for protein oligomerization. They are ordered first by their pain relevance and then by number of times they were reported in protein oligomerization. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT15091 Gene_expression of SLC6A4 101 0.78 29.91 53.64
2 INT49519 Gene_expression of P2rx7 84 0.76 36.88 34.69
3 INT91775 Gene_expression of Slc6a4 102 0.78 26.45 28.23
4 INT74726 Negative_regulation of Slc6a4 61 0.59 21.01 27.84
5 INT15089 Regulation of SLC6A4 48 0.62 17.87 25.6
6 INT76743 Gene_expression of Slc6a4 55 0.76 13.53 24.9
7 INT100423 Gene_expression of Bax 141 0.75 98.43 24.48
8 INT88327 Gene_expression of P2rx7 109 0.77 48.86 22.41
9 INT73593 Gene_expression of BAX 173 0.76 147.81 20.94
10 INT23787 Positive_regulation of P2rx7 36 0.68 23.54 19.45
11 INT97984 Negative_regulation of SLC6A4 45 0.59 15.43 18.09
12 INT48540 Gene_expression of Kcna5 37 0.77 14.04 16.07
13 INT57734 Binding of SLC6A4 36 0.48 11.94 15.42
14 INT109511 Gene_expression of Bax 133 0.78 113.22 14.36
15 INT121241 Positive_regulation of P2rx7 65 0.69 40.94 13.59
16 INT100096 Regulation of Slc6a4 24 0.62 7.25 12.28
17 INT47743 Negative_regulation of Slc6a4 22 0.59 6.23 12.23
18 INT86698 Gene_expression of Cav1 38 0.78 16.37 11.75
19 INT65627 Negative_regulation of Kcna5 19 0.59 7.82 10.79
20 INT66303 Regulation of Slc6a4 10 0.45 4.82 10.55
21 INT15888 Positive_regulation of Nbr1 42 0.69 35.76 10.48
22 INT73427 Localization of P2rx7 24 0.79 8.65 9.87
23 INT102110 Positive_regulation of Gene_expression of Bax 42 0.67 35.77 9.51
24 INT47744 Binding of Slc6a4 21 0.48 5.52 9.45
25 INT102106 Positive_regulation of Bax 48 0.67 30.62 9.28
26 INT73596 Positive_regulation of Gene_expression of BAX 43 0.67 40.97 9.22
27 INT48257 Negative_regulation of P2rx7 18 0.41 7.82 8.42
28 INT73595 Positive_regulation of BAX 61 0.61 56.97 7.82
29 INT103909 Gene_expression of NOD2 37 0.77 21.9 7.36
30 INT15887 Gene_expression of Nbr1 39 0.77 23.91 7.34
31 INT102107 Negative_regulation of Gene_expression of Bax 30 0.57 29.48 7.33
32 INT65630 Regulation of Kcna5 11 0.62 6.61 7.22
33 INT119651 Binding of Slc6a4 12 0.32 4.65 7.07
34 INT15092 Positive_regulation of SLC6A4 17 0.67 7.32 6.7
35 INT87775 Phosphorylation of Gja1 13 0.82 2.75 6.56
36 INT23174 Gene_expression of NLRP3 51 0.72 35.49 6.47
37 INT98837 Positive_regulation of Bax 72 0.61 63.14 6.41
38 INT48541 Positive_regulation of Kcna5 12 0.69 5.51 6.35
39 INT88326 Negative_regulation of P2rx7 16 0.58 8.77 6.25
40 INT94608 Regulation of P2rx7 19 0.23 8.06 6.19
41 INT109714 Transcription of SLC6A4 7 0.72 3.8 6.19
42 INT68882 Binding of P2rx7 16 0.23 4.33 6.17
43 INT145680 Regulation of P2rx7 22 0.61 11.92 5.42
44 INT145929 Regulation of Bax 20 0.60 18.12 5.35
45 INT137593 Regulation of Gene_expression of SLC6A4 7 0.60 2.59 5.23
46 INT119711 Positive_regulation of Slc6a4 16 0.69 4.44 5.21
47 INT109513 Positive_regulation of Gene_expression of Bax 37 0.67 29.52 5.06
48 INT122675 Negative_regulation of Gene_expression of Slc6a4 14 0.59 6.4 4.69
49 INT99504 Negative_regulation of Bax 19 0.56 8.89 4.44
50 INT185484 Positive_regulation of Gene_expression of P2rx7 8 0.31 7.44 4.28
51 INT87780 Gene_expression of Gja1 22 0.77 5.84 4.24
52 INT101858 Negative_regulation of BAX 25 0.57 23.77 4.16
53 INT84686 Regulation of BAX 26 0.49 28.54 4.13
54 INT79343 Positive_regulation of Slc6a4 10 0.50 1.77 4.05
55 INT141443 Phosphorylation of Cav1 6 0.82 4.39 4.03
56 INT123752 Regulation of Bax 19 0.60 16.45 4
57 INT112692 Localization of Bax 31 0.80 20.97 3.98
58 INT144830 Positive_regulation of Gene_expression of P2rx7 22 0.68 9.78 3.92
59 INT32553 Regulation of Pfkm 7 0.62 0.64 3.89
60 INT140670 Negative_regulation of Gene_expression of SLC6A4 4 0.51 2.7 3.88
61 INT103021 Transcription of Slc6a4 16 0.70 3.93 3.77
62 INT15982 Positive_regulation of NLRP3 25 0.65 23.19 3.57
63 INT124579 Localization of BAX 35 0.78 30.31 3.43
64 INT129441 Regulation of Gene_expression of P2rx7 8 0.24 4.29 3.32
65 INT99291 Transcription of Slc6a4 7 0.46 1.16 3.28
66 INT127455 Positive_regulation of Gene_expression of Slc6a4 9 0.59 5.62 3.2
67 INT144828 Binding of P2rx7 19 0.47 7.84 3.16
68 INT100190 Regulation of Gene_expression of Slc6a4 5 0.39 1.8 3.14
69 INT11202 Positive_regulation of Pfkm 8 0.57 1.74 3.06
70 INT65628 Regulation of Gene_expression of Kcna5 4 0.61 1.66 2.98
71 INT124438 Regulation of Gene_expression of Slc6a4 9 0.62 3.5 2.97
72 INT103910 Binding of NOD2 19 0.47 12.24 2.93
73 INT292058 Positive_regulation of Cav2 7 0.67 3.43 2.89
74 INT77339 Positive_regulation of RRM2 5 0.41 1.36 2.88
75 INT53707 Negative_regulation of RRM1 4 0.59 0.44 2.87
76 INT65629 Positive_regulation of Gene_expression of Kcna5 5 0.69 2.48 2.76
77 INT149314 Negative_regulation of CAV2 5 0.42 1.21 2.76
78 INT116215 Transcription of Kcna5 6 0.53 3.62 2.75
79 INT86703 Positive_regulation of Gene_expression of Cav1 7 0.70 3.58 2.73
80 INT282270 Gene_expression of Cav2 11 0.57 3.53 2.72
81 INT162792 Gene_expression of NOD1 19 0.71 6.11 2.71
82 INT116216 Negative_regulation of Gene_expression of Kcna5 4 0.43 3.11 2.64
83 INT107216 Negative_regulation of Gene_expression of P2rx7 10 0.56 3.39 2.61
84 INT159121 Positive_regulation of Map3k1 10 0.45 8.79 2.6
85 INT35465 Negative_regulation of Pfkm 8 0.57 3.84 2.6
86 INT80320 Negative_regulation of Gene_expression of Slc6a4 4 0.42 0.85 2.6
87 INT99800 Binding of Kcna5 4 0.47 0.96 2.55
88 INT102146 Phosphorylation of Bax 4 0.66 3.48 2.35
89 INT120726 Positive_regulation of Gene_expression of Slc6a4 4 0.68 0.51 2.34
90 INT11201 Gene_expression of Pfkm 3 0.18 0.43 2.33
91 INT31994 Negative_regulation of Nbr1 7 0.41 5.54 2.29
92 INT10612 Localization of NLRP3 13 0.78 8.91 2.27
93 INT136614 Positive_regulation of Cav1 5 0.46 2.28 2.23
94 INT176088 Gene_expression of Tek 39 0.65 14.25 2.19
95 INT152554 Regulation of Transcription of SLC6A4 3 0.62 1.52 2.18
96 INT151878 Gene_expression of CAV2 18 0.66 9.26 2.17
97 INT103966 Negative_regulation of Gene_expression of BAX 9 0.56 7.95 2.14
98 INT87778 Positive_regulation of Gene_expression of Gja1 6 0.69 1.46 2.14
99 INT77627 Regulation of Gene_expression of BAX 14 0.44 15.09 2.12
100 INT144829 Localization of P2rx7 12 0.79 2.92 2.12
101 INT154970 Localization of Bax 15 0.74 11.12 2.11
102 INT287525 Localization of CAV2 5 0.47 5.32 2
103 INT195430 Regulation of Positive_regulation of SLC6A4 1 0.42 1.01 1.98
104 INT112089 Gene_expression of Cav1 73 0.75 23.8 1.97
105 INT125974 Localization of Slc6a4 5 0.66 2.27 1.97
106 INT98836 Transcription of Bax 6 0.69 5.04 1.96
107 INT87779 Positive_regulation of Gja1 4 0.53 0.9 1.95
108 INT24453 Binding of NLRP3 18 0.48 13.7 1.93
109 INT95400 Negative_regulation of Map3k1 3 0.15 0.78 1.92
110 INT134442 Transcription of Bax 14 0.67 7.6 1.9
111 INT292051 Negative_regulation of Cav2 6 0.41 2.52 1.9
112 INT135540 Negative_regulation of Bax 16 0.48 11.8 1.89
113 INT243017 Negative_regulation of Binding of Slc6a4 1 0.25 0.22 1.89
114 INT128030 Gene_expression of GJA1 23 0.75 7.81 1.88
115 INT153719 Gene_expression of TEK 10 0.49 9.82 1.88
116 INT208890 Gene_expression of Irak1 7 0.65 2.42 1.87
117 INT87776 Positive_regulation of Phosphorylation of Gja1 3 0.62 0.71 1.86
118 INT134443 Binding of Bax 10 0.47 5.62 1.84
119 INT216936 Negative_regulation of Gene_expression of P2rx7 5 0.42 2.59 1.84
120 INT117221 Positive_regulation of Gene_expression of NOD2 7 0.65 4.39 1.83
121 INT141937 Negative_regulation of Regulation of SLC6A4 1 0.41 0.27 1.8
122 INT162793 Regulation of NOD2 6 0.45 7.61 1.78
123 INT104883 Positive_regulation of Positive_regulation of Bax 4 0.45 4.05 1.74
124 INT131751 Localization of Kcna5 1 0.71 0 1.7
125 INT141444 Positive_regulation of Phosphorylation of Cav1 1 0.70 1.76 1.69
126 INT71788 Gene_expression of MAP3K1 13 0.70 4.9 1.66
127 INT135955 Positive_regulation of Cav1 17 0.48 7.73 1.61
128 INT23786 Positive_regulation of Positive_regulation of P2rx7 5 0.44 2.21 1.58
129 INT125735 Transcription of P2rx7 3 0.62 1.34 1.58
130 INT147808 Positive_regulation of Gene_expression of SLC6A4 4 0.50 1.03 1.57
131 INT37005 Regulation of Nbr1 6 0.24 6.33 1.56
132 INT104015 Regulation of Gene_expression of Pfkm 1 0.01 0 1.54
133 INT23171 Negative_regulation of NLRP3 7 0.37 4.15 1.53
134 INT146785 Positive_regulation of Localization of Bax 7 0.69 6.16 1.47
135 INT215757 Transcription of P2rx7 3 0.21 1.84 1.45
136 INT109512 Negative_regulation of Gene_expression of Bax 12 0.42 8.04 1.44
137 INT205691 Regulation of Gene_expression of P2rx7 5 0.44 3.25 1.42
138 INT50785 Gene_expression of Map3k1 6 0.44 4.22 1.32
139 INT117219 Positive_regulation of NOD2 9 0.69 4.66 1.31
140 INT205690 Positive_regulation of Positive_regulation of P2rx7 14 0.68 6.26 1.3
141 INT204766 Gene_expression of Nod2 4 0.75 4.14 1.3
142 INT112695 Negative_regulation of Protein_catabolism of Bax 3 0.36 1.72 1.3
143 INT136574 Regulation of TNFAIP3 2 0.11 1.33 1.3
144 INT154969 Positive_regulation of Localization of Bax 4 0.64 3.42 1.27
145 INT141862 Binding of Cav1 11 0.36 1.32 1.25
146 INT314186 Gene_expression of Npm1 1 0.01 1.78 1.22
147 INT112693 Protein_catabolism of Bax 5 0.74 3.17 1.2
148 INT191527 Positive_regulation of Gene_expression of NLRP3 6 0.50 8.65 1.15
149 INT88568 Positive_regulation of RRM1 4 0.41 1.81 1.14
150 INT47839 Localization of Slc6a4 4 0.79 0.96 1.14
151 INT141189 Negative_regulation of Transcription of Bax 1 0.41 1.42 1.14
152 INT147286 Negative_regulation of Regulation of Slc6a4 1 0.21 0 1.13
153 INT281849 Binding of RRM2 5 0.17 0.43 1.07
154 INT128444 Phosphorylation of SLC6A4 2 0.61 0.49 1.02
155 INT134822 Gene_expression of Gja1 18 0.72 4.2 1
156 INT216661 Regulation of Positive_regulation of P2rx7 1 0.07 0 1
157 INT154227 Regulation of Gene_expression of NOD2 3 0.44 3.38 0.99
158 INT129674 Regulation of Negative_regulation of Slc6a4 1 0.38 0.46 0.98
159 INT43145 Regulation of Regulation of Pfkm 1 0.45 0 0.97
160 INT136613 Negative_regulation of Cav1 2 0.57 2.28 0.96
161 INT113887 Positive_regulation of Negative_regulation of P2rx7 1 0.22 1.02 0.96
162 INT175507 Regulation of Gene_expression of Bax 13 0.50 10.91 0.95
163 INT22456 Localization of Nbr1 4 0.70 2.71 0.95
164 INT98134 Binding of BAX 17 0.39 11.45 0.93
165 INT22455 Binding of Nbr1 8 0.21 10.57 0.93
166 INT156976 Gene_expression of TNFAIP3 4 0.65 5.25 0.93
167 INT292059 Positive_regulation of Gene_expression of Cav2 3 0.42 0.88 0.92
168 INT131649 Positive_regulation of Negative_regulation of Slc6a4 2 0.44 0.32 0.91
169 INT286694 Positive_regulation of Localization of Slc6a4 1 0.26 0 0.9
170 INT99801 Regulation of Binding of Kcna5 1 0.26 0.14 0.9
171 INT152101 Regulation of Transcription of Slc6a4 1 0.14 0 0.89
172 INT254188 Positive_regulation of Irak1 7 0.44 3.46 0.87
173 INT303636 Gene_expression of OAS1 6 0.56 2.29 0.87
174 INT141442 Negative_regulation of Phosphorylation of Cav1 1 0.59 0.94 0.87
175 INT151776 Positive_regulation of Transcription of P2rx7 1 0.03 0.53 0.86
176 INT137512 Positive_regulation of Positive_regulation of BAX 5 0.49 4.91 0.85
177 INT347182 Negative_regulation of TNFAIP3 3 0.23 5.6 0.84
178 INT71784 Positive_regulation of Gene_expression of MAP3K1 4 0.34 4.8 0.82
179 INT144697 Regulation of Gene_expression of Bax 8 0.37 9.5 0.81
180 INT87777 Regulation of Gja1 1 0.62 0.76 0.81
181 INT82896 Transcription of BAX 3 0.67 4.61 0.8
182 INT50784 Positive_regulation of Gene_expression of Map3k1 2 0.06 0.94 0.8
183 INT112090 Negative_regulation of Gene_expression of Cav1 8 0.57 3.5 0.78
184 INT271589 Regulation of Transcription of P2rx7 1 0.05 0.5 0.78
185 INT148984 Positive_regulation of Localization of BAX 6 0.48 5.29 0.77
186 INT177933 Positive_regulation of MAP3K1 6 0.42 4.13 0.76
187 INT143306 Positive_regulation of Gja1 3 0.50 0.42 0.75
188 INT243015 Regulation of Binding of Slc6a4 1 0.16 0.43 0.75
189 INT178116 Phosphorylation of GJA1 7 0.80 4.09 0.74
190 INT147809 Localization of SLC6A4 5 0.71 1.69 0.74
191 INT152326 Regulation of Gene_expression of CAV2 2 0.36 0.44 0.74
192 INT112088 Regulation of Cav1 2 0.44 0.51 0.73
193 INT128402 Negative_regulation of Phosphorylation of Gja1 1 0.58 0.73 0.73
194 INT151877 Positive_regulation of Gene_expression of CAV2 2 0.40 0.39 0.72
195 INT152909 Regulation of Gene_expression of Gja1 1 0.61 0.46 0.69
196 INT168411 Binding of Irak1 1 0.18 1.08 0.68
197 INT87781 Regulation of Phosphorylation of Gja1 1 0.27 0 0.67
198 INT125734 Negative_regulation of Transcription of P2rx7 1 0.38 0.81 0.67
199 INT246207 Positive_regulation of GJA1 3 0.67 0.91 0.65
200 INT264003 Positive_regulation of Transcription of TNFAIP3 1 0.38 1.01 0.65
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