GO:0051345

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Name positive regulation of hydrolase activity
Categary Process
Go Slim No
Go Link GO:0051345
Unique Molecular Interactions 49
Total Molecular Interactions 79
Total Single Events 441
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of hydrolase activity. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of hydrolase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT307781 Apoa1 Positive_regulation of LCAT 1 0.76 1.19 0.45
2 INT213027 Binding of Apoa1 and Scarb1 6 0.09 7.52 0.43
3 INT307780 Apoa1 Positive_regulation of Soat1 1 0.04 1.14 0.42
4 INT214658 Fabp1 Regulation of Gene_expression of Il6 1 0.02 0.59 0.27
5 INT213029 Positive_regulation of Binding of Apoa1 and Scarb1 1 0.09 3.38 0.27
6 INT305798 Binding of APOA1 and OxP-11D 1 0.02 0.45 0.23
7 INT189321 Binding of Apoa1 and Hdlcl1 1 0.00 0.68 0.2
8 INT300193 Binding of APOA1 and INSL4 1 0.01 2.17 0.18
9 INT213042 Apoa1 Positive_regulation of Nos3 1 0.10 2.17 0.11
10 INT328370 Binding of CD36 and Fabp1 1 0.01 0.64 0.11
11 INT305780 Binding of APOA1 and LRCH2 1 0.00 0.19 0.1
12 INT300192 Gene_expression of APOA1 Positive_regulation of HSD11B1 1 0.16 1.08 0.08
13 INT279652 PPARA Positive_regulation of Gene_expression of Apoa1 1 0.00 0.75 0.07
14 INT301632 Binding of Dbi and Fabp1 1 0.13 0.49 0.07
15 INT326067 APOA1 Positive_regulation of Localization of APOE 1 0.61 4.22 0.07
16 INT335047 PPARA Positive_regulation of Gene_expression of APOA1 1 0.20 0.42 0.05
17 INT239348 Binding of Apoa1 and Hdl1 1 0.03 3.34 0.05
18 INT296023 Positive_regulation of Apoa2 Negative_regulation of APOA1 1 0.50 0.35 0.05
19 INT296025 Apoa2 Negative_regulation of APOA1 1 0.47 0.35 0.05
20 INT236722 Ppara Positive_regulation of Binding of Apoa1 1 0.10 0.18 0.04
21 INT301627 Binding of Fabp1 and Ppara 1 0.21 0.49 0.04
22 INT288908 Apoa1 Positive_regulation of Gene_expression of HSD11B1 1 0.03 0.53 0.04
23 INT247439 Binding of APOA1 and HSD11B1 3 0.32 5.01 0.03
24 INT229811 Fos Positive_regulation of Fabp1 1 0.57 0.2 0.03
25 INT239345 Apoa1 Positive_regulation of RCT 1 0.02 1.15 0.03
26 INT165191 Fabp1 Positive_regulation of Havcr1 1 0.03 0.21 0
27 INT239332 Hdl1 Positive_regulation of Gene_expression of Apoa1 1 0.04 0.84 0
28 INT165198 Positive_regulation of Binding of IL18 and Fabp1 1 0.01 0.55 0
29 INT247444 Binding of APOA1 and APOC3 1 0.28 0.39 0
30 INT213017 Apoa1 Negative_regulation of Positive_regulation of Gtf3a 1 0.00 1.16 0
31 INT247436 Binding of APOA1 and SACM1L 1 0.27 0.39 0
32 INT290193 Binding of APOA1 and Hdl1 1 0.01 1 0
33 INT301635 Ppara Positive_regulation of Gene_expression of Fabp1 1 0.26 0.29 0
34 INT239353 CETP Regulation of Apoa1 1 0.16 0.65 0
35 INT239342 Lcat Regulation of Apoa1 1 0.16 0.65 0
36 INT326060 Binding of ABCA1 and APOA1 1 0.39 1.5 0
37 INT326058 Negative_regulation of PRKCA Negative_regulation of APOA1 1 0.15 0.32 0
38 INT326059 APOA1 Positive_regulation of Gene_expression of APOE 1 0.61 0.38 0
39 INT326064 APOA1 Positive_regulation of HMGCR 1 0.16 0.19 0
40 INT213043 Regulation of Binding of Apoa1 and Scarb1 1 0.05 1.12 0
41 INT239321 Binding of Abca1 and Apoa1 1 0.11 1.61 0
42 INT239319 Pltp Regulation of Apoa1 1 0.22 0.65 0
43 INT165196 Binding of IL18 and Fabp1 1 0.01 0.55 0
44 INT326057 APOA1 Regulation of Localization of APOE 1 0.54 1.36 0
45 INT300197 Binding of APOA1 and C1S 1 0.39 3.56 0
46 INT239350 Eef1a2 Positive_regulation of Apoa1 1 0.22 0.86 0
47 INT247440 Binding of APOA1 and APOB 1 0.28 1.02 0
48 INT304270 Binding of Apoa1 and Scarb1 1 0.00 0.39 0
49 INT326066 APOA1 Positive_regulation of Positive_regulation of HMGCR 1 0.17 0.19 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of hydrolase activity. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of hydrolase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT8579 Gene_expression of Apoa1 13 0.76 35.89 7.21
2 INT74614 Positive_regulation of Apoa1 16 0.68 23.95 5.04
3 INT181886 Gene_expression of Apoa1 40 0.64 40.53 4.56
4 INT10830 Regulation of Apoa1 11 0.44 15.1 3.04
5 INT21712 Positive_regulation of APOA1 32 0.67 21.64 2.64
6 INT100544 Positive_regulation of Fabp1 16 0.38 6.81 2.63
7 INT181880 Positive_regulation of Apoa1 19 0.66 21.19 2.43
8 INT214649 Localization of Fabp1 1 0.44 6.06 2.19
9 INT49313 Positive_regulation of Gene_expression of Apoa1 3 0.68 9.55 2.01
10 INT22863 Negative_regulation of Apoa1 10 0.57 10.68 1.86
11 INT72676 Gene_expression of APOA1 34 0.75 34.15 1.67
12 INT168248 Gene_expression of Fabp1 3 0.43 7.42 1.66
13 INT156484 Binding of Apoa1 4 0.47 6.78 1.63
14 INT181881 Positive_regulation of Gene_expression of Apoa1 13 0.48 14.31 1.45
15 INT181882 Localization of Apoa1 8 0.71 7.94 1.37
16 INT181879 Negative_regulation of Apoa1 8 0.55 8.18 1.11
17 INT72672 Positive_regulation of Gene_expression of APOA1 4 0.67 3.81 0.89
18 INT53852 Binding of Fabp1 1 0.02 0.21 0.85
19 INT181885 Binding of Apoa1 7 0.35 5.66 0.84
20 INT163928 Regulation of Fabp1 3 0.34 2.56 0.72
21 INT181888 Regulation of Apoa1 5 0.26 5.07 0.6
22 INT213118 Negative_regulation of Gene_expression of Apoa1 2 0.42 2.86 0.6
23 INT20239 Regulation of APOA1 10 0.60 10.98 0.51
24 INT190882 Regulation of Gene_expression of Apoa1 4 0.23 3.67 0.43
25 INT190691 Negative_regulation of APOA1 12 0.42 15.9 0.39
26 INT181883 Negative_regulation of Negative_regulation of Apoa1 1 0.40 1.24 0.39
27 INT214657 Positive_regulation of Localization of Fabp1 1 0.38 1.18 0.38
28 INT72673 Transcription of APOA1 2 0.52 1.2 0.36
29 INT214650 Positive_regulation of Positive_regulation of Fabp1 1 0.38 0.98 0.35
30 INT261209 Localization of Apoa1 4 0.73 2.61 0.33
31 INT214653 Regulation of Positive_regulation of Fabp1 1 0.34 1.45 0.33
32 INT307779 Positive_regulation of Localization of Apoa1 1 0.49 0.88 0.31
33 INT189968 Binding of APOA1 12 0.47 10.1 0.3
34 INT214656 Negative_regulation of Localization of Fabp1 1 0.24 0.81 0.29
35 INT214655 Positive_regulation of Gene_expression of Fabp1 1 0.28 1.29 0.29
36 INT163929 Negative_regulation of Fabp1 3 0.32 1.69 0.26
37 INT292837 Gene_expression of Fabp1 13 0.71 2.73 0.22
38 INT301533 Positive_regulation of Gene_expression of Fabp1 6 0.37 1.32 0.2
39 INT190874 Negative_regulation of Gene_expression of Apoa1 1 0.15 0.9 0.2
40 INT239275 Regulation of Localization of Apoa1 1 0.19 1.62 0.18
41 INT214654 Positive_regulation of Regulation of Fabp1 1 0.28 0.7 0.17
42 INT297577 Localization of APOA1 12 0.65 4.58 0.15
43 INT252219 Negative_regulation of Binding of Apoa1 1 0.16 0.95 0.15
44 INT190693 Negative_regulation of Regulation of APOA1 1 0.09 1.94 0.11
45 INT214652 Regulation of Localization of Fabp1 1 0.25 0.36 0.11
46 INT301590 Binding of Fabp1 6 0.21 2.12 0.1
47 INT214651 Regulation of Gene_expression of Fabp1 1 0.25 0.43 0.08
48 INT335114 Negative_regulation of Transcription of APOA1 1 0.16 0.46 0.04
49 INT255452 Negative_regulation of Gene_expression of APOA1 1 0.41 2.46 0.03
50 INT301528 Positive_regulation of Fabp1 1 0.20 0.12 0.03
51 INT267959 Negative_regulation of Positive_regulation of APOA1 2 0.41 1.4 0
52 INT301575 Regulation of Fabp1 1 0.12 0.22 0
53 INT326078 Positive_regulation of Negative_regulation of APOA1 1 0.40 0.32 0
54 INT326072 Negative_regulation of Localization of APOA1 1 0.34 0.38 0
55 INT255448 Positive_regulation of Binding of APOA1 1 0.48 2.88 0
56 INT255449 Positive_regulation of Positive_regulation of APOA1 1 0.48 1.44 0
57 INT301521 Positive_regulation of Binding of Fabp1 1 0.22 1 0
58 INT326079 Regulation of Localization of APOA1 1 0.36 0.24 0
59 INT213117 Negative_regulation of Positive_regulation of Apoa1 1 0.07 0.54 0
60 INT326068 Positive_regulation of Localization of APOA1 1 0.40 1.76 0
61 INT288894 Regulation of Localization of Apoa1 1 0.14 0.42 0
62 INT317764 Negative_regulation of Fabp1 1 0.32 0 0
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