GO:0051385

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Name response to mineralocorticoid stimulus
Categary Process
Go Slim No
Go Link GO:0051385
Unique Molecular Interactions 60
Total Molecular Interactions 68
Total Single Events 666
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for response to mineralocorticoid stimulus. They are ordered first by their pain relevance and then by number of times they were reported for response to mineralocorticoid stimulus. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT253895 Binding of Htr1b and Htr1d 1 0.40 0.52 1.74
2 INT249498 Src Positive_regulation of Phosphorylation of Grin2b 1 0.22 1.11 1.54
3 INT95325 HTR1B Negative_regulation of Calca 1 0.47 0.69 1.43
4 INT249487 Binding of Ephb1 and Src 1 0.17 0.74 1.23
5 INT249488 Positive_regulation of Binding of Ephb1 and Src 1 0.23 0.68 1.12
6 INT121743 Negative_regulation of Src Negative_regulation of Ephb1 1 0.27 0 1.02
7 INT121744 Src Positive_regulation of Positive_regulation of Ephb1 1 0.35 0 0.96
8 INT122269 Src Negative_regulation of Positive_regulation of Grin2b 1 0.27 0.44 0.92
9 INT122266 Src Negative_regulation of Grin2b 1 0.27 0.43 0.91
10 INT249491 Efnb2 Positive_regulation of Phosphorylation of Src 1 0.01 0.5 0.87
11 INT26231 Binding of GSR and HTR1B 1 0.12 0.15 0.66
12 INT249489 Src Negative_regulation of Phosphorylation of Grin2b 1 0.20 0.63 0.66
13 INT100225 Binding of Egf and Src 1 0.01 0.67 0.58
14 INT70468 Binding of HTR1B and MTG1 1 0.40 0 0.56
15 INT160203 Prkcc Positive_regulation of Src 1 0.02 0 0.51
16 INT98737 Src Negative_regulation of Tk1 1 0.22 0.15 0.5
17 INT98735 Src Negative_regulation of Egf 1 0.26 0.15 0.5
18 INT67983 Positive_regulation of HTR1B Positive_regulation of Localization of GHRH 1 0.42 0 0.47
19 INT155881 Binding of CDX2 and KRAS 1 0.40 1.51 0.47
20 INT138384 Binding of Htr1b and ADHD1 2 0.07 1.46 0.42
21 INT91545 Binding of HTR1B and CALCRL 1 0.01 0.09 0.41
22 INT156122 Phosphorylation of Src Positive_regulation of Adrbk1 1 0.01 0 0.37
23 INT263380 Binding of Src and Abl1 1 0.21 0 0.37
24 INT263434 Src Regulation of Abl1 1 0.02 0.29 0.35
25 INT263382 Src Regulation of Trib3 1 0.00 0.29 0.35
26 INT80205 HTR1B Positive_regulation of Positive_regulation of HTR2A 1 0.54 0 0.33
27 INT249490 Phosphorylation of Ephb2 Positive_regulation of Src 1 0.17 0.15 0.33
28 INT249480 Positive_regulation of Ephb1 Positive_regulation of Phosphorylation of Src 1 0.22 0.23 0.31
29 INT163903 Binding of EFNB1 and Src 1 0.03 0.56 0.29
30 INT249493 Binding of Grin2b and Src 1 0.17 0.15 0.26
31 INT128432 HTR1B Regulation of S100A4 1 0.49 0.28 0.24
32 INT153457 Tgfb1 Positive_regulation of Gene_expression of Ctgf 1 0.13 1.15 0.19
33 INT153460 Inhba Positive_regulation of Gene_expression of Ctgf 1 0.77 1.14 0.19
34 INT153461 Tnf Positive_regulation of Gene_expression of Ctgf 1 0.48 1.13 0.19
35 INT300305 Mapk14 Positive_regulation of Gene_expression of Ctgf 1 0.19 1.25 0.17
36 INT294109 Binding of DNASE1L3 and HTR1B 1 0.01 0 0.15
37 INT153458 Ctgf Positive_regulation of Gene_expression of Il6 1 0.34 1.03 0.15
38 INT294448 KLK4 Negative_regulation of CTGF 1 0.01 0 0.1
39 INT70467 Negative_regulation of Binding of HTR1B and MTG1 1 0.46 0 0.09
40 INT257342 Mapk4 Positive_regulation of Gene_expression of Ctgf 1 0.01 0.39 0.08
41 INT257221 Negative_regulation of Binding of Src and Pde5a 1 0.03 0 0.08
42 INT257219 Binding of Src and Pde5a 1 0.02 0 0.08
43 INT76195 Binding of HTR1A and HTR1B 1 0.40 0 0.04
44 INT263377 Abl1 Regulation of Src 1 0.15 0 0.04
45 INT263381 Trib3 Regulation of Src 1 0.01 0 0.04
46 INT229006 MIA3 Positive_regulation of Phosphorylation of Src 1 0.02 0.44 0.03
47 INT232057 Binding of KRAS and RNPC3 1 0.00 0.31 0
48 INT215698 Lamtor1 Negative_regulation of Kras 1 0.00 0 0
49 INT268517 MYC Regulation of CTGF 1 0.03 0.92 0
50 INT350426 Binding of BRAF and KRAS 1 0.05 1.78 0
51 INT180666 Fn1 Regulation of Transcription of Kras 1 0.31 0 0
52 INT232051 Binding of FOXM1 and KRAS 1 0.00 0.63 0
53 INT180669 Fn1 Regulation of Kras 1 0.18 0 0
54 INT215696 Cdkn2a Negative_regulation of Kras 1 0.00 0 0
55 INT215702 Stmn1 Negative_regulation of Kras 1 0.00 0 0
56 INT319319 Binding of EGFR and KRAS 1 0.22 0.27 0
57 INT215688 Cdkn2b Negative_regulation of Kras 1 0.00 0 0
58 INT350433 KRAS Regulation of Gene_expression of BRAF 1 0.08 1.77 0
59 INT215703 Binding of Kras and Cdk6 1 0.01 0 0
60 INT265547 Positive_regulation of Tp53 Positive_regulation of Gene_expression of Kras 1 0.01 0.93 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for response to mineralocorticoid stimulus. They are ordered first by their pain relevance and then by number of times they were reported in response to mineralocorticoid stimulus. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT9282 Gene_expression of HTR1B 48 0.75 12.15 22.94
2 INT9782 Binding of HTR1B 43 0.47 12.08 19.83
3 INT9358 Positive_regulation of HTR1B 26 0.67 11 17.51
4 INT89842 Phosphorylation of Src 34 0.69 9.57 13.08
5 INT89845 Positive_regulation of Src 19 0.44 7.5 9.01
6 INT56580 Positive_regulation of Htr1b 16 0.67 2.95 7.97
7 INT13041 Binding of Htr1b 14 0.47 4.92 7.95
8 INT6892 Regulation of Htr1b 9 0.60 1.32 7.24
9 INT25772 Regulation of HTR1B 15 0.60 3.8 7.17
10 INT15553 Negative_regulation of Htr1b 13 0.41 2.61 7.16
11 INT79822 Gene_expression of Htr1b 10 0.65 2.92 6.27
12 INT96510 Localization of Htr1b 6 0.78 2.31 5.51
13 INT100222 Binding of Src 9 0.26 5.41 5.37
14 INT66305 Negative_regulation of HTR1B 9 0.57 1.7 5.15
15 INT89844 Positive_regulation of Phosphorylation of Src 10 0.43 4.71 4.95
16 INT100220 Negative_regulation of Src 13 0.41 6.37 4.93
17 INT116220 Localization of HTR1B 5 0.78 1.86 3.75
18 INT122327 Regulation of Src 6 0.59 0.59 3.6
19 INT53706 Positive_regulation of Kras 13 0.67 9.26 3.57
20 INT59706 Transcription of HTR1B 5 0.69 0.4 3.4
21 INT156148 Gene_expression of CTGF 16 0.78 9.98 2.87
22 INT9357 Positive_regulation of Positive_regulation of HTR1B 5 0.49 0.88 2.47
23 INT168658 Regulation of Gene_expression of HTR1B 2 0.44 2.11 2.44
24 INT140091 Gene_expression of Ctgf 26 0.78 14.21 2.39
25 INT111039 Gene_expression of Kras 20 0.60 15.42 2.39
26 INT29402 Gene_expression of Src 16 0.74 4.57 2.29
27 INT96403 Transcription of Htr1b 2 0.67 0.81 2.14
28 INT249530 Positive_regulation of Positive_regulation of Src 3 0.28 1.32 1.9
29 INT253894 Regulation of Localization of Htr1b 1 0.44 0.61 1.82
30 INT92383 Gene_expression of KRAS 38 0.65 32.94 1.32
31 INT60060 Positive_regulation of KRAS 17 0.67 11.68 1.21
32 INT66306 Negative_regulation of Transcription of HTR1B 1 0.42 0.14 1.15
33 INT249522 Positive_regulation of Binding of Src 1 0.22 0.68 1.12
34 INT124167 Regulation of Positive_regulation of Src 2 0.13 0.47 1.1
35 INT204058 Regulation of Gene_expression of Kras 4 0.24 7.54 1.01
36 INT111035 Positive_regulation of Gene_expression of Kras 5 0.31 3.31 0.99
37 INT100221 Negative_regulation of Phosphorylation of Src 2 0.24 0.74 0.93
38 INT164079 Regulation of Gene_expression of CTGF 4 0.44 2 0.9
39 INT249506 Regulation of Phosphorylation of Src 1 0.13 0.48 0.77
40 INT92382 Positive_regulation of Gene_expression of KRAS 7 0.49 4.82 0.71
41 INT253893 Negative_regulation of Gene_expression of Htr1b 1 0.41 0.08 0.67
42 INT123722 Positive_regulation of Localization of Htr1b 1 0.49 0.19 0.63
43 INT235996 Negative_regulation of Gene_expression of Src 3 0.09 1.29 0.58
44 INT116221 Positive_regulation of Localization of HTR1B 1 0.49 0.07 0.56
45 INT77516 Negative_regulation of Positive_regulation of Htr1b 1 0.41 0.07 0.55
46 INT133526 Regulation of Transcription of HTR1B 1 0.26 0 0.55
47 INT117998 Positive_regulation of Gene_expression of Src 4 0.36 1.45 0.51
48 INT158296 Positive_regulation of Gene_expression of Ctgf 5 0.47 4.82 0.47
49 INT249504 Localization of Src 1 0.36 0.32 0.46
50 INT140090 Negative_regulation of Gene_expression of Ctgf 5 0.58 1.77 0.44
51 INT75982 Positive_regulation of Binding of Htr1b 1 0.49 0 0.43
52 INT98708 Binding of KRAS 13 0.47 7.47 0.39
53 INT268558 Regulation of CTGF 5 0.23 4.7 0.37
54 INT119248 Binding of Ctgf 1 0.35 1.5 0.35
55 INT98203 Negative_regulation of KRAS 5 0.42 2.38 0.34
56 INT153465 Regulation of Gene_expression of Ctgf 3 0.61 2.5 0.33
57 INT249533 Regulation of Localization of Src 1 0.22 0.22 0.32
58 INT80207 Positive_regulation of Gene_expression of HTR1B 1 0.49 0 0.31
59 INT168140 Regulation of Ctgf 2 0.60 2.15 0.29
60 INT219162 Localization of CTGF 1 0.50 2.62 0.29
61 INT294476 Negative_regulation of CTGF 1 0.27 1.86 0.29
62 INT164080 Negative_regulation of Gene_expression of CTGF 1 0.41 0.51 0.29
63 INT29141 Binding of Kras 3 0.15 0.81 0.27
64 INT136840 Positive_regulation of Ctgf 2 0.35 1.34 0.27
65 INT191481 Negative_regulation of Positive_regulation of HTR1B 1 0.41 0.07 0.23
66 INT117439 Negative_regulation of Positive_regulation of Kras 1 0.42 1.31 0.2
67 INT249526 Positive_regulation of Localization of Src 1 0.24 0.1 0.16
68 INT219160 Positive_regulation of CTGF 2 0.29 2.95 0.15
69 INT153463 Localization of Ctgf 1 0.65 0.97 0.13
70 INT127918 Negative_regulation of Kras 2 0.17 0.66 0.08
71 INT331321 Protein_catabolism of KRAS 1 0.07 0.97 0.08
72 INT127916 Localization of Kras 1 0.29 0 0.08
73 INT338740 Transcription of Src 1 0.43 1.24 0.07
74 INT76244 Negative_regulation of Negative_regulation of HTR1B 1 0.41 0 0.07
75 INT142555 Positive_regulation of Positive_regulation of Kras 1 0.35 0.6 0.07
76 INT156147 Positive_regulation of Gene_expression of CTGF 1 0.70 0.14 0.07
77 INT207240 Regulation of Gene_expression of KRAS 2 0.28 1.31 0.06
78 INT294235 Negative_regulation of Binding of KRAS 1 0.05 0 0.05
79 INT271818 Negative_regulation of Ctgf 1 0.21 0.41 0.04
80 INT207233 Transcription of KRAS 3 0.48 1.56 0.03
81 INT348616 Negative_regulation of Gene_expression of KRAS 1 0.31 0.34 0.03
82 INT236621 Regulation of KRAS 7 0.53 6.16 0
83 INT180396 Localization of KRAS 3 0.69 2.89 0
84 INT304076 Regulation of Localization of KRAS 2 0.36 2.39 0
85 INT175421 Positive_regulation of Positive_regulation of KRAS 2 0.34 1.45 0
86 INT338741 Negative_regulation of Binding of Src 1 0.30 0.75 0
87 INT342935 Positive_regulation of Transcription of Ctgf 1 0.33 0 0
88 INT315376 Negative_regulation of Binding of Kras 1 0.04 0.12 0
89 INT178925 Negative_regulation of Gene_expression of Kras 1 0.07 1.34 0
90 INT76243 Regulation of Regulation of HTR1B 1 0.26 0 0
91 INT342929 Transcription of Ctgf 1 0.38 0 0
92 INT180682 Transcription of Kras 1 0.67 0 0
93 INT268556 Regulation of Positive_regulation of CTGF 1 0.23 1.81 0
94 INT102998 Positive_regulation of Binding of HTR1B 1 0.49 0.1 0
95 INT315374 Regulation of Kras 1 0.02 0.24 0
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