GO:0051393

From wiki-pain
Jump to: navigation, search
Name alpha-actinin binding
Categary Function
Go Slim No
Go Link GO:0051393
Unique Molecular Interactions 29
Total Molecular Interactions 48
Total Single Events 268
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for alpha-actinin binding. They are ordered first by their pain relevance and then by number of times they were reported for alpha-actinin binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT168609 Binding of Itgb1 and Mmp9 1 0.02 0.41 1.58
2 INT189671 DAG1 Positive_regulation of PRKCA 3 0.12 0.71 0.82
3 INT263236 DAG1 Positive_regulation of Prkcg 2 0.01 0.31 0.7
4 INT189670 CHKB Negative_regulation of Gene_expression of DAG1 1 0.11 0 0.24
5 INT335464 Binding of DAG1 and PRKCA 1 0.03 0 0.22
6 INT210795 Ihh Negative_regulation of Itgb1 1 0.30 0 0.17
7 INT327879 Binding of Itgb1 and Postn 1 0.02 1.05 0.14
8 INT327877 Itgb1 Negative_regulation of Gene_expression of Dlk1 1 0.02 0.99 0.13
9 INT352763 Sms Regulation of Gene_expression of DAG1 1 0.08 0.64 0.11
10 INT243996 Binding of Dag1 and Dmd 1 0.04 0.08 0.11
11 INT271525 ITGB1 Positive_regulation of Gopc 1 0.02 0.57 0.11
12 INT257665 Binding of Nphs1 and Pard3 1 0.39 0.67 0.09
13 INT244027 Binding of Dag1 and Helt 1 0.00 0.05 0.08
14 INT283126 Dag1 Positive_regulation of Localization of Aqp4 1 0.47 0.2 0.07
15 INT352766 DAG1 Positive_regulation of Prkd1 1 0.15 0.38 0.07
16 INT317416 Binding of FN1 and ITGB1 1 0.47 0.69 0.05
17 INT352762 DAG1 Regulation of Sms 1 0.03 0.37 0.05
18 INT352764 DAG1 Positive_regulation of Sms 1 0.06 0.11 0.03
19 INT321402 Binding of NPHS1 and PIK3CD 1 0.02 0.73 0.03
20 INT257662 Binding of Mbp and Nphs1 1 0.11 0 0
21 INT238575 Binding of Cask and Magi1 1 0.04 0.17 0
22 INT257663 Binding of Nck1 and Nphs1 1 0.09 0 0
23 INT230762 Binding of DAG1 and Tbx15 1 0.00 0.21 0
24 INT297688 Binding of Fut1 and Nphs1 1 0.03 0 0
25 INT238570 Regulation of Binding of Cask and Magi1 1 0.03 0.17 0
26 INT283122 Binding of Dag1 and Sptbn1 1 0.00 0.07 0
27 INT257664 Regulation of Binding of Nphs1 and Pard3 1 0.36 0 0
28 INT276587 Binding of Iqgap1 and Nphs1 1 0.08 0.33 0
29 INT352765 DAG1 Regulation of Localization of Prkd1 1 0.09 0.09 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for alpha-actinin binding. They are ordered first by their pain relevance and then by number of times they were reported in alpha-actinin binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT94453 Gene_expression of ITGB1 50 0.75 18.41 4.72
2 INT44784 Gene_expression of NPHS1 8 0.64 9.75 1.74
3 INT168602 Negative_regulation of Itgb1 3 0.21 1.29 1.73
4 INT57973 Positive_regulation of ITGB1 5 0.67 1.23 1.44
5 INT173328 Positive_regulation of DAG1 6 0.31 1.74 1.36
6 INT202817 Gene_expression of Dag1 16 0.75 7.82 1.3
7 INT189771 Gene_expression of DAG1 5 0.27 4.14 1.12
8 INT227925 Negative_regulation of Gene_expression of ITGB1 1 0.02 2.19 1.12
9 INT211095 Negative_regulation of Dag1 14 0.57 7.18 1.07
10 INT161882 Negative_regulation of Gene_expression of NPHS1 2 0.41 6.54 0.95
11 INT64044 Localization of DAG1 3 0.59 0.27 0.87
12 INT113672 Positive_regulation of Gene_expression of ITGB1 3 0.49 1.4 0.86
13 INT283119 Regulation of Dag1 4 0.44 1.98 0.65
14 INT283110 Localization of Dag1 5 0.73 3.14 0.61
15 INT145225 Transcription of ITGB1 1 0.10 0.1 0.52
16 INT19581 Regulation of NPHS1 3 0.25 2.38 0.5
17 INT19582 Binding of NPHS1 1 0.02 0.28 0.4
18 INT283120 Regulation of Gene_expression of Dag1 4 0.52 1.32 0.38
19 INT284325 Positive_regulation of Gene_expression of DAG1 3 0.13 1.08 0.36
20 INT119073 Negative_regulation of ITGB1 1 0.01 0.1 0.33
21 INT339443 Negative_regulation of Nphs1 1 0.16 1.24 0.23
22 INT286203 Protein_catabolism of Dag1 2 0.26 1.56 0.22
23 INT316917 Negative_regulation of Protein_catabolism of Dag1 1 0.12 0.44 0.21
24 INT283102 Positive_regulation of Dag1 1 0.49 1.31 0.21
25 INT225973 Binding of Itgb1 2 0.08 1.1 0.2
26 INT245860 Gene_expression of Itgb1 8 0.42 5.37 0.19
27 INT243937 Binding of Dag1 1 0.05 0.13 0.19
28 INT283105 Positive_regulation of Gene_expression of Dag1 1 0.67 1.19 0.17
29 INT222042 Localization of ITGB1 3 0.29 0.72 0.12
30 INT283103 Regulation of Localization of Dag1 1 0.44 0.32 0.09
31 INT238505 Regulation of Gene_expression of NPHS1 1 0.29 2.93 0.06
32 INT341884 Positive_regulation of Localization of DAG1 1 0.03 0.21 0.06
33 INT352747 Regulation of DAG1 1 0.16 0.99 0.05
34 INT257647 Localization of Nphs1 1 0.71 0.34 0.05
35 INT321416 Phosphorylation of NPHS1 1 0.12 1.5 0.05
36 INT257641 Binding of Nphs1 1 0.46 0.33 0.04
37 INT321427 Negative_regulation of Phosphorylation of NPHS1 1 0.07 0.79 0.03
38 INT321418 Negative_regulation of NPHS1 1 0.07 0.79 0.03
39 INT257642 Gene_expression of Nphs1 4 0.66 0.96 0
40 INT268299 Positive_regulation of Gene_expression of Itgb1 2 0.38 1.37 0
41 INT257638 Positive_regulation of Nphs1 1 0.66 0.22 0
42 INT257644 Positive_regulation of Gene_expression of Nphs1 1 0.48 0 0
43 INT225977 Regulation of Binding of Itgb1 1 0.07 0.41 0
44 INT352742 Regulation of Gene_expression of DAG1 1 0.12 0.14 0
45 INT257643 Regulation of Nphs1 1 0.26 0.62 0
46 INT245366 Regulation of Itgb1 1 0.03 0 0
47 INT230759 Binding of DAG1 1 0.03 0.21 0
48 INT355317 Negative_regulation of Gene_expression of Itgb1 1 0.20 0.14 0
49 INT283107 Transcription of Dag1 1 0.61 0.44 0
50 INT257651 Regulation of Binding of Nphs1 1 0.43 0 0
51 INT291604 Binding of ITGB1 1 0.05 0.16 0
52 INT283101 Negative_regulation of Gene_expression of Dag1 1 0.57 0.96 0
53 INT257633 Positive_regulation of Binding of Nphs1 1 0.66 0 0
54 INT238604 Binding of Magi1 1 0.06 0.26 0
55 INT283113 Regulation of Transcription of Dag1 1 0.52 0.44 0
56 INT257637 Negative_regulation of Positive_regulation of Nphs1 1 0.41 0 0
57 INT280923 Localization of Itgb1 1 0.40 0.72 0
58 INT352733 Negative_regulation of Localization of DAG1 1 0.11 0.06 0
59 INT175647 Regulation of Gene_expression of ITGB1 1 0.01 0.4 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox