GO:0051434

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Name BH3 domain binding
Categary Function
Go Slim No
Go Link GO:0051434
Unique Molecular Interactions 486
Total Molecular Interactions 624
Total Single Events 6590
Pain Genes Associated 11

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for BH3 domain binding. They are ordered first by their pain relevance and then by number of times they were reported for BH3 domain binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT156008 Bcl2 Regulation of Localization of Aifm1 1 0.17 1.92 1.47
2 INT145930 ecs Positive_regulation of Gene_expression of Bcl2 1 0.01 2.06 1.34
3 INT73597 Positive_regulation of BAX Positive_regulation of Casp1 1 0.06 0.69 1.28
4 INT73598 BAX Positive_regulation of Casp1 1 0.06 0.63 1.27
5 INT142202 FL Positive_regulation of Bcl2 1 0.05 0.39 0.99
6 INT112765 Binding of Nfkb1 and Bcl2 1 0.00 1.37 0.91
7 INT166634 Binding of Bcl2 and Becn1 1 0.20 0.5 0.86
8 INT150864 RYBP Positive_regulation of Positive_regulation of Bcl2 1 0.01 0.66 0.86
9 INT97057 Bcl2l1 Regulation of Gene_expression of Trp53 1 0.36 0.51 0.83
10 INT97056 Cpz Regulation of Gene_expression of Bcl2l1 1 0.22 0.57 0.83
11 INT218935 Cyp3a23/3a1 Regulation of Bcl2 1 0.00 1.08 0.74
12 INT320633 Positive_regulation of MAPK1 Regulation of BCL2 1 0.04 1.21 0.7
13 INT296793 Akt1 Positive_regulation of Gene_expression of Bax 1 0.11 0.75 0.65
14 INT296790 Tlr9 Regulation of Bax 1 0.14 0.76 0.65
15 INT296791 Positive_regulation of Akt1 Positive_regulation of Gene_expression of Bax 1 0.11 0.8 0.65
16 INT296785 Tlr9 Regulation of Bcl2 1 0.19 0.76 0.65
17 INT83800 Aap Regulation of Gene_expression of Bcl2l1 1 0.28 0.58 0.64
18 INT112699 Bid Regulation of Bax 1 0.25 0.51 0.61
19 INT302839 MIR15A Negative_regulation of Bcl2 1 0.15 1.41 0.47
20 INT238639 Cd86 Negative_regulation of Negative_regulation of Bcl2 1 0.01 0.97 0.46
21 INT112772 Binding of Bcl2 and SGSM3 1 0.02 0.69 0.45
22 INT238638 Gopc Negative_regulation of Gene_expression of Bax 1 0.04 0.85 0.45
23 INT116613 Lnpep Negative_regulation of Gene_expression of BAX 1 0.42 0.62 0.43
24 INT116609 Lnpep Negative_regulation of Bcl2 1 0.05 0.62 0.43
25 INT116606 Lnpep Regulation of Gene_expression of Bcl2 1 0.07 0.62 0.43
26 INT116607 Lnpep Negative_regulation of Gene_expression of Bcl2 1 0.10 0.62 0.43
27 INT116612 Lnpep Negative_regulation of BAX 1 0.42 0.62 0.42
28 INT309143 Dlat Positive_regulation of Bcl2 1 0.06 1.04 0.42
29 INT309152 Dlat Positive_regulation of Gene_expression of Bcl2 1 0.04 1.05 0.42
30 INT235878 Creb1 Positive_regulation of Gene_expression of Bcl2 1 0.05 0.17 0.38
31 INT155062 Csf2 Positive_regulation of Transcription of Bcl2 1 0.31 2.91 0.36
32 INT172213 Binding of BAX and BCL2L1 3 0.22 4.02 0.35
33 INT264555 IL15 Positive_regulation of Gene_expression of BCL2 1 0.02 0.92 0.35
34 INT155061 Stat3 Negative_regulation of Bax 1 0.22 3.71 0.34
35 INT269962 Bcl2 Negative_regulation of Bcl2l11 1 0.15 2.14 0.34
36 INT155060 Stat3 Negative_regulation of Bcl2 1 0.21 3.7 0.33
37 INT242398 Cyp19a1 Positive_regulation of Bcl2 1 0.00 1.28 0.3
38 INT163762 MDM2 Positive_regulation of Gene_expression of BAX 1 0.27 0.86 0.3
39 INT218928 Cyp3a23/3a1 Regulation of Transcription of Bcl2 1 0.00 0.56 0.28
40 INT260837 NRP2 Negative_regulation of Negative_regulation of Bcl2 1 0.00 0.9 0.28
41 INT172905 Binding of Bad and Bcl2 3 0.08 6.46 0.27
42 INT172901 Binding of Bad and Bcl2l1 3 0.13 6.51 0.27
43 INT237927 BCL2 Positive_regulation of BAX 2 0.24 2.22 0.26
44 INT237928 BCL2 Positive_regulation of FAS 1 0.02 1.41 0.26
45 INT272157 Gh1 Negative_regulation of Bcl2 1 0.23 1.2 0.26
46 INT272158 Gh1 Regulation of Bcl2 1 0.15 1.2 0.26
47 INT237919 BAX Positive_regulation of Protein_catabolism of PARP1 1 0.03 1.41 0.26
48 INT237925 BCL2 Positive_regulation of Protein_catabolism of PARP1 1 0.02 1.42 0.26
49 INT260840 NRP2 Positive_regulation of Gene_expression of Bcl2 1 0.00 0.85 0.24
50 INT302170 PTGER2 Positive_regulation of Gene_expression of BCL2 1 0.04 3.76 0.23
51 INT279965 STAT3 Regulation of Transcription of BCL2L1 1 0.10 2.31 0.19
52 INT155063 Csf2 Negative_regulation of Gene_expression of Bax 1 0.27 1.46 0.18
53 INT176133 AKT1 Regulation of BCL2 2 0.12 1.84 0.17
54 INT285026 Bak1 Regulation of Bcl2 1 0.09 0.71 0.17
55 INT285022 Regulation of Bak1 Regulation of Bcl2 1 0.09 0.71 0.17
56 INT155066 Csf2 Negative_regulation of Bax 1 0.12 1.89 0.17
57 INT349475 Regulation of Bax Regulation of Bcl2 1 0.07 1.35 0.17
58 INT155233 TXNIP Regulation of BCL2 1 0.23 0.15 0.17
59 INT285024 Bcl2 Regulation of Bak1 1 0.09 0.71 0.17
60 INT229203 Binding of Bcl2 and Cyp2c11 1 0.36 1.2 0.17
61 INT155068 Csf2 Negative_regulation of Bcl2 1 0.12 1.88 0.17
62 INT155232 TXNIP Regulation of BAX 1 0.23 0.15 0.17
63 INT347445 CD99 Positive_regulation of BCL2 1 0.17 0.95 0.16
64 INT336891 Epo Negative_regulation of Transcription of Bax 1 0.10 0.68 0.16
65 INT333255 Cxcl12 Regulation of Mcl1 1 0.12 1.12 0.15
66 INT292750 Akt1 Positive_regulation of Bcl2 1 0.01 1.67 0.15
67 INT349476 Bax Regulation of Bcl2 1 0.07 1.33 0.15
68 INT130918 HMHA1 Positive_regulation of BAX 1 0.04 1.37 0.14
69 INT311666 Binding of BCL2 and TP53 1 0.19 1.26 0.14
70 INT95104 TGFBR2 Positive_regulation of BCL2 1 0.08 0.61 0.14
71 INT273040 Vip Regulation of Bax 1 0.23 1.69 0.13
72 INT309139 Edc4 Positive_regulation of Bcl2 1 0.03 0.12 0.13
73 INT148594 Binding of BCL2 and CD34 1 0.39 1.17 0.13
74 INT309142 Edc4 Regulation of Bcl2 1 0.02 0.12 0.13
75 INT246016 Negative_regulation of Timp1 Negative_regulation of Gene_expression of Bcl2 1 0.03 1.07 0.13
76 INT333396 CFD Positive_regulation of Bcl2l1 1 0.05 0.98 0.13
77 INT273041 Adcyap1 Regulation of Bax 1 0.21 1.69 0.13
78 INT342311 Binding of Tp53 and Positive_regulation of Gene_expression of BCL2 1 0.08 1.25 0.13
79 INT348542 BCL2 Negative_regulation of NLRP1 1 0.07 2.02 0.13
80 INT246017 Timp1 Negative_regulation of Gene_expression of Bcl2 1 0.03 1.07 0.13
81 INT172899 Binding of Bcl2 and Bcl2l1 3 0.02 5.54 0.12
82 INT226192 Protein_catabolism of Bax Positive_regulation of Gtf3a 1 0.00 0.53 0.12
83 INT178101 EDN1 Negative_regulation of Phosphorylation of BCL2 1 0.03 1 0.12
84 INT305194 Bcl2 Positive_regulation of Epo 1 0.06 0.29 0.12
85 INT273063 Negative_regulation of Fas Negative_regulation of Positive_regulation of Bcl2 1 0.01 0.72 0.11
86 INT285030 Binding of Bax and Slc25a4 1 0.03 0.84 0.11
87 INT221684 Binding of Bcl2 and FRTS 1 0.01 1.19 0.11
88 INT265888 BCL2 Regulation of Gene_expression of BAD 1 0.04 1.08 0.1
89 INT265890 BCL2 Regulation of Gene_expression of BAX 1 0.04 1.08 0.1
90 INT265889 BAX Regulation of Gene_expression of BAD 1 0.06 1.08 0.1
91 INT310743 TP53 Regulation of BAX 1 0.09 1.11 0.1
92 INT279962 Binding of A1BG and BCL2L1 1 0.13 1.11 0.1
93 INT239643 Binding of BCL2 and BCL2L11 3 0.16 2.26 0.09
94 INT282094 Apoa2 Negative_regulation of BCL2 1 0.06 1.15 0.09
95 INT275184 Bad Positive_regulation of Positive_regulation of Bcl2l1 1 0.12 0.62 0.09
96 INT275183 Bad Positive_regulation of Gene_expression of Bcl2 1 0.08 0.63 0.09
97 INT265887 IGF1 Negative_regulation of BCL2 1 0.09 1.02 0.09
98 INT294637 Bcl2a1a Positive_regulation of Gene_expression of Bcl2 1 0.15 0.97 0.09
99 INT204300 Bcl2 Negative_regulation of Positive_regulation of Bak1 1 0.02 1.13 0.09
100 INT350908 Binding of Bcl2 and Twist1 1 0.04 1.9 0.08
101 INT201456 Hmox1 Positive_regulation of Gene_expression of Bcl2 1 0.06 0.74 0.08
102 INT204299 Bcl2 Negative_regulation of Localization of Aifm1 1 0.06 1.22 0.07
103 INT285032 Bnip3 Positive_regulation of Bax 1 0.28 0.77 0.07
104 INT242482 Ciapin1 Positive_regulation of Gene_expression of Bcl2l1 1 0.31 1.05 0.07
105 INT340401 Positive_regulation of Bax Positive_regulation of Binding of Hrk 1 0.01 0.79 0.07
106 INT297733 Cbr1 Regulation of Gene_expression of Bcl2 1 0.05 0.94 0.07
107 INT340395 Binding of Bax and Tg(CAG-EGFP)D4Nagy 1 0.02 0.43 0.07
108 INT302177 PTGER2 Positive_regulation of BCL2 1 0.04 2.08 0.06
109 INT302175 BAX Regulation of Positive_regulation of CASP9 1 0.02 0.7 0.06
110 INT302129 BAX Regulation of Positive_regulation of CASP3 1 0.02 0.69 0.06
111 INT352299 Regulation of Binding of BCL2 and VIM 1 0.10 1.07 0.06
112 INT352298 Binding of BCL2 and VIM 1 0.09 1.06 0.06
113 INT224696 TNF Positive_regulation of Gene_expression of Mcl1 1 0.01 1.07 0.05
114 INT304172 Il5 Positive_regulation of Bcl2l1 1 0.02 0.91 0.05
115 INT341375 Sod2 Regulation of Bcl2 1 0.08 1.96 0.05
116 INT348523 BCL2L1 Negative_regulation of NLRP1 1 0.01 0.63 0.05
117 INT190824 Binding of Cl and Bcl2 1 0.02 1.4 0.05
118 INT333252 Positive_regulation of Binding of Bcl2 and Mcl1 1 0.03 0.88 0.04
119 INT234379 BAX Positive_regulation of CASP3 1 0.04 1.16 0.04
120 INT268665 Ptger2 Positive_regulation of Gene_expression of Mcl1 1 0.03 0.9 0.04
121 INT268664 Ptger2 Positive_regulation of Bcl2 1 0.02 0.9 0.04
122 INT172214 BAX Positive_regulation of TP53 1 0.09 0.37 0.04
123 INT333245 Binding of Bcl2 and Bcl2l11 1 0.03 0.87 0.04
124 INT268666 Ptger2 Positive_regulation of Gene_expression of Bcl2 1 0.02 0.9 0.04
125 INT340394 Binding of Bax and Bbc3 1 0.01 0.36 0.04
126 INT333254 Binding of Mcl1 and Cxcl12 1 0.10 0.88 0.04
127 INT350905 Binding of Bcl2 and Pcsk4 1 0.03 0.96 0.04
128 INT333253 Binding of Bcl2 and Mcl1 1 0.02 2.14 0.04
129 INT333244 Positive_regulation of Binding of Mcl1 and Cxcl12 1 0.13 0.88 0.04
130 INT250025 Map3k1 Positive_regulation of Regulation of Bcl2 1 0.01 1.1 0.04
131 INT106486 Gene_expression of CD177 Negative_regulation of Gene_expression of Bcl2l1 1 0.01 1.87 0.04
132 INT172902 Binding of Bax and Bcl2 5 0.30 3.19 0.03
133 INT192164 Binding of BAK1 and BCL2 3 0.04 2.8 0.03
134 INT192167 Negative_regulation of Binding of BAK1 and BCL2 2 0.05 1.89 0.03
135 INT192165 Binding of BAK1 and BCL2L1 2 0.06 1.35 0.03
136 INT288538 Il2 Positive_regulation of Gene_expression of Bcl2 1 0.04 1.96 0.03
137 INT192166 Negative_regulation of Binding of BAK1 and BCL2L1 1 0.05 1.06 0.03
138 INT297737 Cbr1 Positive_regulation of Bax 1 0.06 0.53 0.03
139 INT172892 Negative_regulation of Lox Negative_regulation of Gene_expression of Mcl1 1 0.06 1.13 0.03
140 INT224682 Mcl1 Regulation of Bak1 1 0.01 1.09 0.03
141 INT217148 MIR21 Regulation of BCL2 1 0.32 0.98 0.03
142 INT238395 BAX Regulation of CDKN1A 1 0.03 0.31 0.03
143 INT101159 Gene_expression of Bcl2 Positive_regulation of Gene_expression of CHAT 1 0.31 0.96 0.03
144 INT298633 STAT3 Regulation of MCL1 1 0.04 0.85 0.03
145 INT172896 Lox Negative_regulation of Gene_expression of Mcl1 1 0.05 1.13 0.03
146 INT229204 Olr1254 Negative_regulation of Gene_expression of Bcl2 1 0.02 0.18 0.03
147 INT333259 Bcl2 Regulation of Bax 1 0.03 0.32 0.03
148 INT172894 Negative_regulation of Lox Negative_regulation of Gene_expression of Bcl2 1 0.03 1.12 0.03
149 INT220445 Bcl2 Negative_regulation of Positive_regulation of Casp9 1 0.01 1.37 0.03
150 INT224689 Binding of Bak1 and Mcl1 1 0.01 1.09 0.03
151 INT224676 Binding of Bax and Mcl1 1 0.01 1.09 0.03
152 INT224690 Mcl1 Regulation of Bax 1 0.00 1.09 0.03
153 INT308750 Binding of BCL2L1 and MIR184 1 0.13 0.11 0.03
154 INT333262 Bcl2 Regulation of Bak1 1 0.04 0.31 0.03
155 INT341376 Sod2 Regulation of Bax 1 0.09 0.99 0.03
156 INT282995 Binding of Bcl2 and Becn1 21 0.03 9.8 0
157 INT185856 Binding of BAD and BCL2L1 4 0.39 2.73 0
158 INT283013 Binding of Bak1 and Bcl2 4 0.06 1.03 0
159 INT185852 Binding of BAK1 and BAX 3 0.29 2.5 0
160 INT178861 Binding of BAX and BCL2 3 0.27 3.07 0
161 INT172906 Binding of Bax and Bcl2l1 2 0.16 2.03 0
162 INT198011 Binding of BAX and MCL1 2 0.20 3.04 0
163 INT292454 Binding of BAD and BCL2 2 0.03 1.73 0
164 INT144032 STAT3 Regulation of BCL2 2 0.07 0.86 0
165 INT217150 MIR16-2 Regulation of BCL2 2 0.09 1.89 0
166 INT217137 MIR15B Regulation of BCL2 2 0.15 1.88 0
167 INT295047 Binding of Bcl2 and Nr4a1 1 0.04 0.96 0
168 INT254089 EPO Regulation of Gene_expression of Bcl2 1 0.03 0.63 0
169 INT285031 Binding of Bcl2 and Bcl2l1 1 0.27 0.1 0
170 INT346522 Binding of MCL1 and PTH 1 0.00 0 0
171 INT295920 Mir761 Positive_regulation of Transcription of Bcl2l1 1 0.00 1.43 0
172 INT321406 VEGFA Regulation of BCL2 1 0.01 0.75 0
173 INT325284 Binding of COMP and MCL1 1 0.01 1.69 0
174 INT217145 Gene_expression of MIR26B Negative_regulation of Gene_expression of MCL1 1 0.10 1 0
175 INT198022 AKT1 Regulation of Gene_expression of MCL1 1 0.15 2.25 0
176 INT292447 Negative_regulation of Binding of BAD and BCL2L1 1 0.02 0.81 0
177 INT217143 MIR29A Regulation of Gene_expression of MCL1 1 0.24 1 0
178 INT198014 Binding of MCL1 and BCL2L11 1 0.11 0.82 0
179 INT295046 Bcl2 Regulation of Gene_expression of Nr4a1 1 0.02 0.92 0
180 INT292503 Mlph Regulation of Gene_expression of BCL2 1 0.00 0.4 0
181 INT185849 Binding of BCL2L1 and BIK 1 0.29 0.59 0
182 INT253474 Positive_regulation of Prkaca Positive_regulation of Gene_expression of Bcl2 1 0.04 1.27 0
183 INT285029 Binding of Bax and Bcl2l1 1 0.25 0.1 0
184 INT330047 Binding of Bax and Bcl2l11 1 0.13 0.62 0
185 INT191058 Binding of Bcl2 and Positive_regulation of Gene_expression of Bax 1 0.21 0.49 0
186 INT333688 Trp53 Positive_regulation of Bcl2 1 0.45 2.51 0
187 INT327971 PNLIP Positive_regulation of Gene_expression of BAX 1 0.43 1.95 0
188 INT292500 Mlph Regulation of Gene_expression of BAX 1 0.00 0.4 0
189 INT333261 Binding of Bcl2l1 and Mcl1 1 0.02 1.25 0
190 INT106380 ARSA Regulation of Gene_expression of BAX 1 0.06 0.12 0
191 INT284919 XRCC6 Negative_regulation of BAX 1 0.01 0.64 0
192 INT321400 VEGFA Negative_regulation of Gene_expression of BAX 1 0.03 0.75 0
193 INT348531 Binding of BCL2 and BECN1 1 0.06 0.43 0
194 INT221240 Akt1 Positive_regulation of Phosphorylation of Bcl2 1 0.00 0.89 0
195 INT191062 Esr1 Regulation of Gene_expression of Bcl2 1 0.12 0.73 0
196 INT242483 Negative_regulation of Ciapin1 Negative_regulation of Positive_regulation of Bax 1 0.17 1.76 0
197 INT267255 Bcl2 Positive_regulation of Gene_expression of Ptprj 1 0.04 0.63 0
198 INT345485 Binding of MCL1 and BBC3 1 0.01 0.79 0
199 INT136914 Mapk8 Positive_regulation of Localization of Bax 1 0.51 0.12 0
200 INT191061 Akt1 Positive_regulation of Bcl2 1 0.41 0.33 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for BH3 domain binding. They are ordered first by their pain relevance and then by number of times they were reported in BH3 domain binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT82650 Gene_expression of Bcl2 312 0.78 211.71 55.03
2 INT77307 Gene_expression of Bcl2 399 0.77 319.77 38
3 INT65960 Gene_expression of BCL2 352 0.78 312.03 30.73
4 INT100423 Gene_expression of Bax 141 0.75 98.43 24.48
5 INT83797 Gene_expression of Bcl2l1 124 0.77 94.55 22.39
6 INT73593 Gene_expression of BAX 173 0.76 147.81 20.94
7 INT93734 Positive_regulation of Gene_expression of Bcl2 76 0.70 61.95 18.46
8 INT86673 Positive_regulation of Bcl2 77 0.70 57.74 17.37
9 INT109511 Gene_expression of Bax 133 0.78 113.22 14.36
10 INT80222 Negative_regulation of Bcl2 82 0.58 69.16 13.18
11 INT81640 Positive_regulation of Gene_expression of Bcl2 106 0.69 84.58 11.63
12 INT99505 Gene_expression of Bcl2l1 42 0.77 33.12 10.15
13 INT102110 Positive_regulation of Gene_expression of Bax 42 0.67 35.77 9.51
14 INT102106 Positive_regulation of Bax 48 0.67 30.62 9.28
15 INT73596 Positive_regulation of Gene_expression of BAX 43 0.67 40.97 9.22
16 INT70017 Positive_regulation of BCL2 87 0.67 66.62 8.68
17 INT86672 Negative_regulation of Bcl2 50 0.53 34.16 8.37
18 INT65959 Positive_regulation of Gene_expression of BCL2 75 0.70 77.3 8.27
19 INT80220 Positive_regulation of Bcl2 71 0.58 57.73 7.86
20 INT73595 Positive_regulation of BAX 61 0.61 56.97 7.82
21 INT77306 Negative_regulation of Gene_expression of Bcl2 46 0.58 38.05 7.71
22 INT91445 Regulation of Bcl2 50 0.56 38.8 7.41
23 INT102107 Negative_regulation of Gene_expression of Bax 30 0.57 29.48 7.33
24 INT93101 Regulation of Gene_expression of Bcl2 26 0.62 18.45 6.71
25 INT84685 Regulation of BCL2 67 0.60 72.96 6.65
26 INT98837 Positive_regulation of Bax 72 0.61 63.14 6.41
27 INT99506 Negative_regulation of Bcl2l1 25 0.58 15.7 6.09
28 INT100422 Negative_regulation of Gene_expression of Bcl2 46 0.58 28.86 5.7
29 INT164587 Gene_expression of MCL1 94 0.75 124.05 5.39
30 INT145929 Regulation of Bax 20 0.60 18.12 5.35
31 INT87420 Gene_expression of BCL2L1 56 0.75 48.84 5.32
32 INT70613 Negative_regulation of Gene_expression of BCL2 48 0.59 38.91 5.22
33 INT73262 Negative_regulation of BCL2 67 0.57 61.01 5.07
34 INT109513 Positive_regulation of Gene_expression of Bax 37 0.67 29.52 5.06
35 INT99507 Positive_regulation of Bcl2l1 17 0.69 9.23 4.97
36 INT116614 Positive_regulation of Gene_expression of Bcl2l1 12 0.67 11.39 4.68
37 INT99504 Negative_regulation of Bax 19 0.56 8.89 4.44
38 INT101957 Transcription of Bcl2 30 0.69 16.57 4.3
39 INT83794 Positive_regulation of Gene_expression of Bcl2l1 26 0.69 16.89 4.28
40 INT83798 Negative_regulation of Gene_expression of Bcl2l1 28 0.58 20.26 4.21
41 INT101858 Negative_regulation of BAX 25 0.57 23.77 4.16
42 INT84686 Regulation of BAX 26 0.49 28.54 4.13
43 INT83796 Regulation of Gene_expression of Bcl2l1 10 0.61 7.85 4.05
44 INT123752 Regulation of Bax 19 0.60 16.45 4
45 INT112692 Localization of Bax 31 0.80 20.97 3.98
46 INT101857 Negative_regulation of BCL2L1 22 0.57 23.56 3.95
47 INT95423 Negative_regulation of Bcl2l1 26 0.41 21.66 3.81
48 INT105882 Phosphorylation of Bcl2 11 0.59 8.15 3.73
49 INT124579 Localization of BAX 35 0.78 30.31 3.43
50 INT109403 Regulation of Gene_expression of BCL2 31 0.60 31.22 3.4
51 INT81642 Regulation of Gene_expression of Bcl2 20 0.44 16.93 3.19
52 INT64234 Regulation of Bcl2 41 0.54 31.88 3.16
53 INT86245 Positive_regulation of Bcl2l1 15 0.46 12.67 3.11
54 INT105884 Binding of Bcl2 19 0.35 15.67 3
55 INT164582 Negative_regulation of MCL1 56 0.56 67.11 2.82
56 INT99508 Regulation of Bcl2l1 12 0.61 10.44 2.71
57 INT156016 Binding of BCL2L1 10 0.36 7.42 2.64
58 INT164588 Regulation of MCL1 12 0.43 14.09 2.63
59 INT102146 Phosphorylation of Bax 4 0.66 3.48 2.35
60 INT147349 Localization of Bcl2 13 0.65 7.83 2.31
61 INT97748 Positive_regulation of BCL2L1 12 0.67 9.83 2.26
62 INT91836 Negative_regulation of Gene_expression of BCL2L1 9 0.49 8.59 2.25
63 INT142677 Negative_regulation of Positive_regulation of Bcl2 4 0.36 3.09 2.24
64 INT101641 Gene_expression of Mcl1 25 0.54 20.3 2.23
65 INT83799 Phosphorylation of Bcl2l1 8 0.82 7.86 2.23
66 INT102752 Positive_regulation of Gene_expression of BCL2L1 14 0.67 13.8 2.19
67 INT103966 Negative_regulation of Gene_expression of BAX 9 0.56 7.95 2.14
68 INT77627 Regulation of Gene_expression of BAX 14 0.44 15.09 2.12
69 INT154970 Localization of Bax 15 0.74 11.12 2.11
70 INT101645 Regulation of Gene_expression of Bcl2l1 8 0.36 5.27 2.05
71 INT86671 Negative_regulation of Positive_regulation of Bcl2 6 0.57 3.83 2.03
72 INT98836 Transcription of Bax 6 0.69 5.04 1.96
73 INT164583 Negative_regulation of Gene_expression of MCL1 19 0.56 22.45 1.94
74 INT134442 Transcription of Bax 14 0.67 7.6 1.9
75 INT135540 Negative_regulation of Bax 16 0.48 11.8 1.89
76 INT101108 Localization of Bcl2 16 0.72 11.68 1.86
77 INT105883 Positive_regulation of Phosphorylation of Bcl2 8 0.32 5.67 1.86
78 INT134443 Binding of Bax 10 0.47 5.62 1.84
79 INT104883 Positive_regulation of Positive_regulation of Bax 4 0.45 4.05 1.74
80 INT97749 Regulation of BCL2L1 10 0.41 9.72 1.65
81 INT101958 Positive_regulation of Transcription of Bcl2 4 0.50 2.22 1.65
82 INT137513 Negative_regulation of Positive_regulation of BCL2 6 0.35 5.3 1.62
83 INT106413 Transcription of Bcl2l1 8 0.53 3.35 1.52
84 INT146785 Positive_regulation of Localization of Bax 7 0.69 6.16 1.47
85 INT166021 Positive_regulation of MCL1 36 0.67 62.97 1.44
86 INT109512 Negative_regulation of Gene_expression of Bax 12 0.42 8.04 1.44
87 INT105881 Phosphorylation of Bcl2l1 3 0.51 1.99 1.31
88 INT112695 Negative_regulation of Protein_catabolism of Bax 3 0.36 1.72 1.3
89 INT101107 Positive_regulation of Localization of Bcl2 3 0.48 3.13 1.28
90 INT154969 Positive_regulation of Localization of Bax 4 0.64 3.42 1.27
91 INT112693 Protein_catabolism of Bax 5 0.74 3.17 1.2
92 INT166016 Protein_catabolism of MCL1 4 0.76 4.05 1.17
93 INT141189 Negative_regulation of Transcription of Bax 1 0.41 1.42 1.14
94 INT143867 Positive_regulation of Mcl1 7 0.58 9.24 1.13
95 INT166022 Positive_regulation of Protein_catabolism of MCL1 1 0.39 1.17 1.12
96 INT198042 Regulation of Gene_expression of MCL1 8 0.26 10.05 1.1
97 INT172855 Binding of Bcl2 37 0.32 23.41 1.09
98 INT70021 Localization of BCL2 23 0.74 21.6 1.09
99 INT135806 Regulation of Bcl2l1 10 0.44 7.21 1.05
100 INT164863 Positive_regulation of Phosphorylation of Bcl2l1 1 0.31 0.57 1.01
101 INT175507 Regulation of Gene_expression of Bax 13 0.50 10.91 0.95
102 INT98134 Binding of BAX 17 0.39 11.45 0.93
103 INT156015 Negative_regulation of Protein_catabolism of BCL2L1 1 0.42 1.23 0.93
104 INT156014 Protein_catabolism of BCL2L1 1 0.64 1.23 0.93
105 INT156017 Positive_regulation of Binding of BCL2L1 1 0.49 1.21 0.91
106 INT151115 Regulation of Regulation of Bcl2 4 0.21 4.12 0.88
107 INT92117 Phosphorylation of BCL2 26 0.80 9.93 0.86
108 INT137512 Positive_regulation of Positive_regulation of BAX 5 0.49 4.91 0.85
109 INT144697 Regulation of Gene_expression of Bax 8 0.37 9.5 0.81
110 INT82896 Transcription of BAX 3 0.67 4.61 0.8
111 INT70019 Binding of BCL2 25 0.47 17.55 0.79
112 INT109404 Transcription of BCL2 6 0.69 4.49 0.77
113 INT148984 Positive_regulation of Localization of BAX 6 0.48 5.29 0.77
114 INT124844 Regulation of Positive_regulation of Bcl2 3 0.43 2.55 0.75
115 INT155392 Negative_regulation of Negative_regulation of Bcl2 3 0.21 1.64 0.74
116 INT134444 Positive_regulation of Binding of Bcl2 3 0.47 2.67 0.72
117 INT131567 Negative_regulation of Positive_regulation of Bcl2l1 1 0.41 0.66 0.7
118 INT166020 Positive_regulation of Regulation of MCL1 1 0.39 0.68 0.69
119 INT131568 Positive_regulation of Positive_regulation of Bcl2l1 1 0.48 0.64 0.68
120 INT166014 Negative_regulation of Negative_regulation of MCL1 1 0.33 0.63 0.61
121 INT70025 Positive_regulation of Positive_regulation of BCL2 3 0.27 0.96 0.58
122 INT101640 Regulation of Gene_expression of Mcl1 2 0.11 1.67 0.58
123 INT86246 Binding of Bcl2l1 8 0.37 6.67 0.57
124 INT178128 Negative_regulation of Phosphorylation of BCL2 7 0.27 3.94 0.56
125 INT158327 Negative_regulation of Mcl1 5 0.42 4.08 0.55
126 INT152057 Negative_regulation of Transcription of Bcl2l1 3 0.43 1 0.55
127 INT158329 Positive_regulation of Gene_expression of Mcl1 9 0.32 7.53 0.54
128 INT155090 Regulation of Positive_regulation of BCL2 3 0.26 1.78 0.54
129 INT176242 Binding of Bax 10 0.42 10.18 0.52
130 INT198027 Localization of MCL1 5 0.72 7.46 0.51
131 INT144696 Regulation of Transcription of Bcl2 5 0.44 2.96 0.51
132 INT152058 Regulation of Transcription of Bcl2l1 2 0.32 0.53 0.5
133 INT134445 Positive_regulation of Positive_regulation of Bcl2 3 0.47 2.43 0.49
134 INT102108 Protein_catabolism of Bax 8 0.64 5.69 0.48
135 INT221676 Protein_catabolism of Bcl2 4 0.24 2.77 0.48
136 INT134446 Positive_regulation of Binding of Bax 1 0.49 0.72 0.48
137 INT198052 Positive_regulation of Gene_expression of MCL1 19 0.48 24.19 0.47
138 INT165799 Negative_regulation of Gene_expression of Bcl2l1 6 0.41 5.12 0.47
139 INT229243 Negative_regulation of Phosphorylation of BAX 1 0.18 2.32 0.47
140 INT106415 Positive_regulation of Transcription of Bcl2l1 1 0.20 0.49 0.46
141 INT204052 Transcription of Bcl2 5 0.51 3.25 0.45
142 INT152056 Negative_regulation of Regulation of Bcl2l1 1 0.58 0.07 0.45
143 INT140295 Protein_catabolism of BCL2 4 0.64 5.7 0.44
144 INT220424 Positive_regulation of Negative_regulation of Bcl2 2 0.14 1.81 0.44
145 INT152059 Regulation of Transcription of Bax 1 0.26 0.07 0.42
146 INT105888 Phosphorylation of BAX 9 0.80 4.78 0.4
147 INT135802 Positive_regulation of Negative_regulation of Bax 2 0.41 0.57 0.4
148 INT158331 Regulation of Mcl1 3 0.15 4.4 0.39
149 INT229233 Positive_regulation of Phosphorylation of BAX 1 0.21 1.94 0.38
150 INT155724 Negative_regulation of Transcription of Bcl2 6 0.53 2.35 0.37
151 INT105885 Binding of Bcl2l1 2 0.05 1.13 0.35
152 INT204069 Negative_regulation of Positive_regulation of Bax 5 0.31 3.08 0.34
153 INT279985 Transcription of BCL2L1 5 0.69 3.76 0.34
154 INT169538 Negative_regulation of Localization of Bax 3 0.49 1.41 0.34
155 INT184482 Positive_regulation of Positive_regulation of Bax 5 0.41 4.7 0.33
156 INT221191 Negative_regulation of Localization of Bax 4 0.38 2.85 0.33
157 INT165917 Negative_regulation of Gene_expression of Mcl1 2 0.23 1.35 0.32
158 INT165912 Negative_regulation of Localization of Mcl1 1 0.23 0.77 0.31
159 INT165918 Localization of Mcl1 1 0.41 0.76 0.31
160 INT165913 Positive_regulation of Localization of Mcl1 1 0.28 0.76 0.31
161 INT109530 Negative_regulation of Positive_regulation of BAX 3 0.42 3.01 0.3
162 INT82900 Positive_regulation of Transcription of BAX 2 0.49 1.86 0.29
163 INT178114 Positive_regulation of Phosphorylation of BCL2 11 0.49 4.44 0.28
164 INT149998 Positive_regulation of Positive_regulation of Bcl2l1 1 0.05 1.73 0.28
165 INT102111 Positive_regulation of Protein_catabolism of Bax 2 0.45 1.14 0.27
166 INT158330 Binding of Mcl1 1 0.14 1.32 0.26
167 INT172227 Regulation of Localization of BAX 3 0.26 4.79 0.24
168 INT180186 Localization of BCL2L1 2 0.33 3.86 0.24
169 INT292743 Negative_regulation of Binding of Bcl2 1 0.05 1.97 0.24
170 INT135543 Negative_regulation of Positive_regulation of Bax 5 0.30 6.4 0.23
171 INT285003 Positive_regulation of Regulation of Bcl2 1 0.46 0.68 0.23
172 INT108563 Negative_regulation of Regulation of Bcl2 1 0.32 0.74 0.22
173 INT187553 Regulation of Transcription of BAX 1 0.37 1.21 0.21
174 INT227671 Protein_catabolism of Bcl2l1 2 0.18 0.96 0.19
175 INT356122 Regulation of Phosphorylation of Bcl2l1 1 0.09 0.69 0.19
176 INT220426 Regulation of Negative_regulation of Bcl2 1 0.05 0.81 0.18
177 INT300463 Regulation of Regulation of Bax 1 0.29 1.33 0.18
178 INT238507 Regulation of Regulation of BCL2 3 0.44 5.14 0.16
179 INT101109 Negative_regulation of Localization of Bcl2 1 0.03 0.62 0.16
180 INT229235 Regulation of Localization of BCL2 2 0.29 3.7 0.15
181 INT102109 Protein_catabolism of Bcl2 1 0.65 0.55 0.15
182 INT110957 Positive_regulation of Positive_regulation of Bcl2 3 0.35 2.3 0.13
183 INT285904 Positive_regulation of Transcription of BCL2L1 1 0.05 0.95 0.13
184 INT179038 Positive_regulation of Regulation of Bcl2 1 0.39 3.49 0.12
185 INT158328 Regulation of Positive_regulation of Mcl1 1 0.11 0.8 0.12
186 INT133486 Negative_regulation of Binding of BAX 1 0.15 0.62 0.12
187 INT336888 Negative_regulation of Transcription of Bax 1 0.07 0.68 0.11
188 INT113990 Regulation of Gene_expression of BCL2L1 3 0.32 2.58 0.1
189 INT304137 Regulation of Localization of Bax 2 0.24 1.7 0.09
190 INT303976 Negative_regulation of Protein_catabolism of BAX 1 0.09 0.24 0.07
191 INT303978 Protein_catabolism of BAX 1 0.13 0.24 0.07
192 INT307466 Positive_regulation of Phosphorylation of Bax 1 0.15 0.76 0.07
193 INT268622 Regulation of Negative_regulation of Bax 1 0.12 0.81 0.05
194 INT254082 Positive_regulation of Localization of Bcl2l1 1 0.09 0.16 0.05
195 INT302229 Negative_regulation of Negative_regulation of BCL2 3 0.21 2.69 0.04
196 INT309494 Negative_regulation of Binding of Bax 2 0.38 1.31 0.04
197 INT172226 Positive_regulation of Negative_regulation of BAX 2 0.48 1.51 0.04
198 INT340387 Regulation of Positive_regulation of Bax 1 0.27 0.61 0.04
199 INT310746 Negative_regulation of Regulation of BAX 1 0.35 1.33 0.04
200 INT254081 Localization of Bcl2l1 1 0.13 0 0.04
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