GO:0051436

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Name negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
Categary Process
Go Slim No
Go Link GO:0051436
Unique Molecular Interactions 32
Total Molecular Interactions 41
Total Single Events 443
Pain Genes Associated 16

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT79602 Binding of PSMA5 and Oprd1 2 0.19 1.05 1.01
2 INT144286 ACP1 Negative_regulation of Phosphorylation of PSMC6 1 0.45 0.39 0.78
3 INT177794 BUB1B Positive_regulation of Gene_expression of ASNS 1 0.11 0.77 0.46
4 INT177781 BUB1B Positive_regulation of ATF4 1 0.07 0.76 0.46
5 INT177780 BUB1B Positive_regulation of ASNS 1 0.05 0.76 0.46
6 INT177787 BUB1B Positive_regulation of MTHFD2 1 0.15 0.76 0.46
7 INT13879 Binding of PSMB9 and KCNAB2 1 0.03 0.19 0.41
8 INT303995 Lep Positive_regulation of PSME1 1 0.09 0.32 0.29
9 INT35178 Binding of STT3A and PSME3 1 0.01 0.38 0.25
10 INT180503 Binding of SARS and PSMD6 1 0.22 2.44 0.16
11 INT57014 PSMB1 Regulation of SCN5A 1 0.02 0 0.1
12 INT298351 PSMD1 Regulation of Gene_expression of HLA-DRA 1 0.01 0.42 0.08
13 INT298356 PSMD1 Regulation of Gene_expression of Cd14 1 0.04 0.42 0.08
14 INT166784 Binding of PSMD1 and Nkx6-2 1 0.21 0.5 0.08
15 INT231605 Binding of PSMD1 and SGCG 1 0.02 0.34 0.04
16 INT261728 PSMB6 Negative_regulation of Transcription of F2R 1 0.01 0.17 0.03
17 INT261731 PSMB6 Regulation of COL5A2 1 0.00 0.21 0.03
18 INT287479 PSMB10 Positive_regulation of TBK1 1 0.00 0.59 0.03
19 INT318081 Binding of RPL5 and UBC 1 0.02 0.52 0
20 INT209454 Binding of PSMD1 and PSMD2 1 0.15 0 0
21 INT165318 Binding of PSMD1 and CHPT1 1 0.23 0.57 0
22 INT276607 Binding of DBT and PSMD1 1 0.00 0.08 0
23 INT209452 Binding of PSMD2 and PSMD3 1 0.07 0.2 0
24 INT318103 Binding of UBC and Hprt 1 0.10 0.52 0
25 INT299698 Binding of CFB and PSMC2 1 0.00 0.14 0
26 INT209453 Binding of PSMD1 and PSMD3 1 0.08 0.2 0
27 INT175194 Binding of UBC and NUP62 1 0.01 0.05 0
28 INT299708 Binding of C3 and PSMC2 1 0.00 0.14 0
29 INT252909 FZR1 Positive_regulation of APC 1 0.06 0.08 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT69592 Positive_regulation of PSMD1 27 0.70 17.83 18.98
2 INT151747 Positive_regulation of PSMD2 26 0.68 17.48 17.89
3 INT141151 Regulation of PSMD1 16 0.40 8.19 5.86
4 INT151748 Positive_regulation of Positive_regulation of PSMD2 4 0.49 4.45 5.35
5 INT17110 Gene_expression of PSMD1 60 0.65 19.57 4.69
6 INT69591 Positive_regulation of Positive_regulation of PSMD1 2 0.50 3.06 3.99
7 INT69593 Negative_regulation of PSMD1 11 0.57 4.06 3.33
8 INT51993 Gene_expression of PSMA5 5 0.75 2.59 2.92
9 INT140547 Negative_regulation of PSMB10 3 0.02 2.33 2.92
10 INT24443 Gene_expression of PSMD2 20 0.54 7.29 2.77
11 INT60440 Localization of PSMD1 10 0.74 3.94 2.57
12 INT106616 Gene_expression of PSMB9 35 0.72 28.4 2.29
13 INT69027 Binding of PSMA5 4 0.47 1.08 1.93
14 INT148721 Binding of PSMD1 13 0.31 4.78 1.76
15 INT159185 Positive_regulation of Gene_expression of PSMD2 3 0.40 1.4 1.63
16 INT164152 Negative_regulation of PSMD2 9 0.37 3.41 1.56
17 INT69513 Regulation of PSMA5 2 0.60 1.04 1.43
18 INT108587 Negative_regulation of PSMA5 1 0.57 1.73 1.42
19 INT6018 Positive_regulation of PSMB9 7 0.60 4.36 1.33
20 INT79660 Phosphorylation of PSMC6 3 0.80 0.45 1.28
21 INT67638 Positive_regulation of PSMA5 1 0.21 1.15 1.05
22 INT13882 Binding of PSMB9 3 0.15 2.84 1
23 INT78322 Positive_regulation of PSME1 2 0.44 1.8 0.95
24 INT144289 Negative_regulation of Positive_regulation of PSMC6 1 0.41 0.56 0.92
25 INT144287 Positive_regulation of PSMC6 1 0.49 0.56 0.92
26 INT78323 Negative_regulation of PSME1 1 0.37 0.5 0.78
27 INT108590 Negative_regulation of Negative_regulation of PSMA5 1 0.57 0.92 0.75
28 INT108586 Positive_regulation of Negative_regulation of PSMA5 1 0.49 0.82 0.67
29 INT17109 Regulation of Gene_expression of PSMD1 3 0.44 0.86 0.58
30 INT16681 Positive_regulation of PSMC2 1 0.07 0 0.54
31 INT177869 Gene_expression of BUB1B 2 0.65 2.11 0.45
32 INT177866 Negative_regulation of BUB1B 1 0.32 1.23 0.45
33 INT177845 Negative_regulation of Gene_expression of BUB1B 1 0.23 0.75 0.45
34 INT350879 Negative_regulation of Localization of PSMD1 1 0.05 0.43 0.43
35 INT202762 Gene_expression of PSMD3 8 0.47 1.44 0.42
36 INT280564 Negative_regulation of Gene_expression of PSMB9 5 0.54 5.99 0.41
37 INT78324 Regulation of PSME1 1 0.61 0.49 0.41
38 INT280560 Positive_regulation of Gene_expression of PSMB9 7 0.64 6.44 0.36
39 INT335718 Regulation of Gene_expression of PSMD2 1 0.09 0.07 0.35
40 INT11689 Binding of PSMD2 16 0.36 2.77 0.34
41 INT57019 Gene_expression of PSMB1 1 0.38 0 0.34
42 INT11688 Binding of PSMD3 5 0.36 1.17 0.28
43 INT131823 Negative_regulation of PSMB6 2 0.01 0.09 0.24
44 INT322282 Localization of PSMD2 2 0.20 1.42 0.22
45 INT209076 Negative_regulation of PSME3 2 0.34 0.86 0.21
46 INT165973 Phosphorylation of PSMA5 1 0.79 0.07 0.2
47 INT165972 Positive_regulation of Phosphorylation of PSMA5 1 0.49 0.07 0.2
48 INT280553 Regulation of PSMB9 2 0.57 1.46 0.19
49 INT209077 Positive_regulation of Negative_regulation of PSME3 1 0.37 0.13 0.19
50 INT57020 Transcription of PSMB1 1 0.26 0 0.16
51 INT90493 Negative_regulation of PSMB9 3 0.54 0.88 0.15
52 INT15564 Regulation of PSMD2 1 0.00 0 0.12
53 INT165320 Protein_catabolism of PSMD1 1 0.61 1.37 0.11
54 INT165319 Regulation of Protein_catabolism of PSMD1 1 0.31 1.37 0.11
55 INT334958 Positive_regulation of Localization of PSMD1 1 0.10 0.87 0.1
56 INT280554 Negative_regulation of Positive_regulation of PSMB9 1 0.40 0.9 0.09
57 INT189116 Gene_expression of PSMB10 1 0.18 0.3 0.08
58 INT285256 Positive_regulation of Negative_regulation of PSMD2 1 0.04 0 0.08
59 INT337665 Positive_regulation of PSME3 1 0.45 2.51 0.07
60 INT166204 Gene_expression of PSME1 3 0.32 1.94 0.05
61 INT202765 Positive_regulation of PSMD3 1 0.12 0.51 0.05
62 INT263801 Localization of PSME1 2 0.07 1.72 0.04
63 INT318095 Gene_expression of UBC 1 0.16 1.24 0.04
64 INT337650 Positive_regulation of Positive_regulation of PSME3 1 0.32 1.33 0.04
65 INT337661 Positive_regulation of Positive_regulation of PSME1 1 0.05 1.31 0.04
66 INT337662 Localization of PSME3 1 0.52 1.26 0.04
67 INT186663 Protein_catabolism of PSMB9 2 0.60 0.39 0.03
68 INT214219 Regulation of PSMD6 1 0.01 0.05 0.03
69 INT214220 Gene_expression of PSMD6 3 0.65 0.83 0
70 INT227884 Positive_regulation of Gene_expression of PSMD1 2 0.06 0.4 0
71 INT87528 Negative_regulation of PSMC6 2 0.41 0 0
72 INT155591 Binding of PSME1 2 0.07 0.49 0
73 INT230109 Positive_regulation of Gene_expression of BUB1B 1 0.42 0.65 0
74 INT248587 Positive_regulation of Gene_expression of PSMD3 1 0.04 0.16 0
75 INT166205 Negative_regulation of Gene_expression of PSME1 1 0.18 0.28 0
76 INT222070 Localization of PSMD3 1 0.04 0.09 0
77 INT302263 Regulation of Phosphorylation of PSMD6 1 0.09 0.84 0
78 INT209457 Negative_regulation of Gene_expression of PSMD1 1 0.27 0.2 0
79 INT175213 Negative_regulation of Binding of UBC 1 0.02 0.13 0
80 INT157670 Regulation of PSMC6 1 0.44 0.58 0
81 INT245611 Positive_regulation of Binding of PSMD2 1 0.43 0.1 0
82 INT156902 Positive_regulation of UBC 1 0.49 0 0
83 INT302249 Positive_regulation of Phosphorylation of PSMD6 1 0.10 0.84 0
84 INT186659 Regulation of Protein_catabolism of PSMB9 1 0.15 0.17 0
85 INT177818 Positive_regulation of PSMB6 1 0.19 0.25 0
86 INT214218 Negative_regulation of PSMD6 1 0.01 0 0
87 INT302251 Phosphorylation of PSMD6 1 0.17 0.84 0
88 INT155592 Positive_regulation of Binding of PSME1 1 0.09 0.1 0
89 INT280550 Regulation of Gene_expression of PSMB9 1 0.57 0.37 0
90 INT343564 Regulation of Gene_expression of PSMD6 1 0.44 0.35 0
91 INT287280 Positive_regulation of Negative_regulation of PSMD1 1 0.10 0 0
92 INT166206 Regulation of Gene_expression of PSME1 1 0.19 0.28 0
93 INT175222 Binding of UBC 1 0.02 0.54 0
94 INT209458 Negative_regulation of Gene_expression of PSMD2 1 0.23 0.2 0
95 INT261736 Gene_expression of PSMB6 1 0.01 0 0
96 INT186626 Protein_catabolism of PSMB6 1 0.16 0.17 0
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