GO:0051452

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Name intracellular pH reduction
Categary Process
Go Slim No
Go Link GO:0051452
Unique Molecular Interactions 16
Total Molecular Interactions 19
Total Single Events 303
Pain Genes Associated 3

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for intracellular pH reduction. They are ordered first by their pain relevance and then by number of times they were reported for intracellular pH reduction. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT326194 Bdnf Regulation of Slc12a5 1 0.05 0.85 1.35
2 INT247924 Slc12a5 Regulation of Gene_expression of Slc12a2 1 0.25 1.43 1.23
3 INT247926 Slc12a5 Regulation of Cl 1 0.01 1.43 1.23
4 INT169096 Hpcl1 Regulation of Gene_expression of Slc12a5 1 0.02 0.05 0.95
5 INT261783 Bdnf Regulation of Gene_expression of Slc12a5 1 0.09 0 0.87
6 INT215596 Bdnf Positive_regulation of Negative_regulation of Slc12a5 1 0.14 0.76 0.86
7 INT261786 Bdnf Negative_regulation of Slc12a5 1 0.14 0.05 0.85
8 INT139131 Negative_regulation of Ltp Negative_regulation of Slc12a5 1 0.17 0.15 0.7
9 INT139132 Ltp Negative_regulation of Slc12a5 1 0.17 0.15 0.69
10 INT139133 Slc12a5 Negative_regulation of Gene_expression of Ltp 1 0.20 0.11 0.59
11 INT261782 Bdnf Positive_regulation of Gene_expression of Slc12a5 1 0.18 0 0.44
12 INT261790 SHC1 Positive_regulation of Slc12a5 1 0.02 0.06 0.41
13 INT261788 Bdnf Regulation of Slc12a5 1 0.10 0.07 0.38
14 INT261784 Positive_regulation of Bdnf Positive_regulation of Slc12a5 1 0.15 0.77 0.2
15 INT239790 SLC12A5 Regulation of SLC12A2 1 0.11 0.08 0.13
16 INT261789 PDGFA Positive_regulation of Slc12a5 1 0.07 0.15 0.12

Single Events

The table below shows the top 100 pain related interactions that have been reported for intracellular pH reduction. They are ordered first by their pain relevance and then by number of times they were reported in intracellular pH reduction. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT103172 Gene_expression of Slc12a5 81 0.77 39.45 36.22
2 INT103169 Negative_regulation of Slc12a5 38 0.58 27.75 20.81
3 INT103170 Negative_regulation of Gene_expression of Slc12a5 26 0.58 17.25 14.4
4 INT138890 Regulation of Slc12a5 12 0.45 11.61 7.46
5 INT103171 Positive_regulation of Slc12a5 15 0.51 3.6 6.25
6 INT165011 Gene_expression of SLC12A5 11 0.77 4.08 4.95
7 INT121252 Regulation of Gene_expression of Slc12a5 10 0.61 6.47 4.87
8 INT126099 Gene_expression of Slc12a5 9 0.77 5.72 4.36
9 INT139130 Positive_regulation of Gene_expression of Slc12a5 8 0.51 4.43 4.33
10 INT139129 Negative_regulation of Negative_regulation of Slc12a5 4 0.43 5.53 4.29
11 INT165013 Negative_regulation of Gene_expression of SLC12A5 3 0.58 3.55 4.22
12 INT203314 Negative_regulation of Gene_expression of Slc12a5 3 0.31 4.74 4.03
13 INT165590 Negative_regulation of Slc12a5 5 0.43 2.62 2.96
14 INT110333 Positive_regulation of Negative_regulation of Slc12a5 4 0.50 3.18 2.77
15 INT244384 Binding of Slc12a5 2 0.46 2.47 1.71
16 INT326191 Localization of Slc12a5 1 0.14 0.85 1.32
17 INT121251 Transcription of Slc12a5 2 0.66 1.72 1.27
18 INT247922 Phosphorylation of Slc12a5 3 0.79 2.42 1.11
19 INT160020 Transcription of Slc12a5 2 0.53 0.75 0.83
20 INT247920 Positive_regulation of Phosphorylation of Slc12a5 2 0.51 0.9 0.63
21 INT203328 Positive_regulation of Gene_expression of Slc12a5 2 0.50 1.56 0.63
22 INT261776 Positive_regulation of Positive_regulation of Slc12a5 1 0.37 0 0.61
23 INT165012 Negative_regulation of SLC12A5 1 0.43 0.37 0.59
24 INT165014 Regulation of SLC12A5 1 0.45 0.37 0.59
25 INT261771 Negative_regulation of Positive_regulation of Slc12a5 1 0.32 0 0.56
26 INT247919 Regulation of Phosphorylation of Slc12a5 1 0.59 1.54 0.54
27 INT247921 Negative_regulation of Phosphorylation of Slc12a5 1 0.56 1.58 0.49
28 INT165591 Negative_regulation of Negative_regulation of Slc12a5 1 0.43 0.35 0.49
29 INT243938 Regulation of Phosphorylation of Slc12a5 1 0.18 1.1 0.48
30 INT243918 Phosphorylation of Slc12a5 1 0.25 1.1 0.48
31 INT243914 Positive_regulation of Slc12a5 1 0.14 0 0.47
32 INT239795 Localization of SLC12A5 1 0.33 0.14 0.28
33 INT243985 Regulation of Slc12a5 1 0.13 0.55 0.24
34 INT203305 Regulation of Gene_expression of Slc12a5 1 0.32 0.8 0.22
35 INT244390 Negative_regulation of Transcription of Slc12a5 1 0.54 0.4 0.2
36 INT261781 Regulation of Positive_regulation of Slc12a5 1 0.20 0.08 0.09
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