GO:0051480

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Name cytosolic calcium ion homeostasis
Categary Process
Go Slim No
Go Link GO:0051480
Unique Molecular Interactions 568
Total Molecular Interactions 896
Total Single Events 11526
Pain Genes Associated 24

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cytosolic calcium ion homeostasis. They are ordered first by their pain relevance and then by number of times they were reported for cytosolic calcium ion homeostasis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT69886 Ngf Positive_regulation of Calca 8 0.76 2.98 12.77
2 INT166591 Binding of CALCA and DCLK3 4 0.30 0.69 12.18
3 INT180785 Gdnf Positive_regulation of Calca 1 0.23 1.96 8.04
4 INT142177 Calca Positive_regulation of Gene_expression of Igf1 8 0.78 3.57 5.71
5 INT69888 Ngf Positive_regulation of Localization of Calca 4 0.52 0.51 4.95
6 INT102122 Binding of Calca and RT1-M4 7 0.29 5.83 4.94
7 INT11599 Calca Positive_regulation of Npr1 5 0.19 0.3 4.8
8 INT24742 Binding of Calca and Vip 1 0.37 0.18 4.68
9 INT128998 Cxcl1 Positive_regulation of Localization of Calca 1 0.66 2.96 4.15
10 INT13969 Binding of Calca and Sst 3 0.32 0.6 4.02
11 INT13966 Calca Positive_regulation of Localization of Sst 5 0.49 0.75 3.91
12 INT85541 Ngf Positive_regulation of Gene_expression of Calca 2 0.55 1.84 3.71
13 INT87491 CALCA Positive_regulation of Gene_expression of IL8 1 0.72 0.92 3.52
14 INT24710 Binding of Calca and SUB1P1 1 0.01 2.09 3.48
15 INT108471 Binding of CALCA and PNOC 1 0.29 0.64 3.25
16 INT74159 Ngf Regulation of Gene_expression of Calca 2 0.60 1.66 3.22
17 INT29657 Binding of Calca and Calcb 1 0.26 0 3.16
18 INT37162 Binding of Calca and Cckar 1 0.04 0.55 3.01
19 INT100835 Binding of Calca and Akap12 1 0.07 0.41 2.92
20 INT166592 Binding of CALCA and RAMP1 2 0.35 0.33 2.91
21 INT73821 CALCA Positive_regulation of Localization of IL8 1 0.25 2.37 2.91
22 INT194409 Binding of CALCA and IGKV1D-8 1 0.15 0 2.84
23 INT169134 Binding of Calca and Trpa1 1 0.37 3.37 2.79
24 INT180779 Bdnf Regulation of Calca 1 0.09 0.23 2.71
25 INT53648 Acot1 Positive_regulation of Localization of Calca 2 0.23 0 2.61
26 INT57624 Calca Regulation of Positive_regulation of Trh 1 0.50 0 2.53
27 INT48526 Binding of Calca and Penk 1 0.24 1.03 2.51
28 INT136129 Calca Positive_regulation of ATP8A2 1 0.38 0.89 2.4
29 INT13967 Calca Positive_regulation of Sst 1 0.45 0 2.3
30 INT152900 TRPV1 Regulation of Gene_expression of CALCA 1 0.69 0.73 2.29
31 INT152901 TRPV1 Regulation of Localization of CALCA 1 0.44 0.73 2.29
32 INT69887 Ngf Regulation of Calca 2 0.49 0.1 2.19
33 INT79470 Mgat4a Regulation of Localization of Calca 1 0.08 1.72 2.1
34 INT89733 Binding of Calca and Nrm 1 0.31 0.71 2.09
35 INT63873 SRPX Positive_regulation of Localization of Calca 1 0.02 0.49 2.04
36 INT115042 Gdnf Regulation of Calca 1 0.53 0.25 2.03
37 INT26221 Calca Regulation of Gt(pU21)50Imeg 1 0.01 0 2.02
38 INT128996 Ccl2 Positive_regulation of Localization of Calca 1 0.68 1.43 2
39 INT213968 Binding of Calca and Mthfd1 1 0.05 0.16 1.99
40 INT120723 Positive_regulation of Trpv1 Positive_regulation of Localization of Calca 3 0.51 0.48 1.92
41 INT24942 Calca Regulation of TAC1 1 0.13 0.7 1.89
42 INT271408 NGF Positive_regulation of Gene_expression of CALCA 1 0.09 4.89 1.88
43 INT168723 Positive_regulation of Trpv1 Positive_regulation of Gene_expression of Calca 1 0.48 1.1 1.84
44 INT163514 Ngf Positive_regulation of Gene_expression of Calca 1 0.30 2.21 1.82
45 INT24934 Calca Regulation of Nka1 3 0.05 0.43 1.73
46 INT148090 Binding of CALCA and NCOR2 1 0.00 0.65 1.71
47 INT94617 KNG1 Positive_regulation of Localization of Calca 1 0.00 0.75 1.7
48 INT56134 CALCA Positive_regulation of POMC 2 0.71 0.72 1.68
49 INT102447 Binding of CALCA and CALCRL 2 0.26 0.33 1.67
50 INT145826 Calca Positive_regulation of Gene_expression of Igf1 3 0.75 3.05 1.66
51 INT94618 KNG1 Positive_regulation of Calca 1 0.00 0.75 1.66
52 INT144213 Nppa Positive_regulation of Localization of Calca 1 0.71 2.8 1.65
53 INT23889 Calca Positive_regulation of Localization of Tacr1 1 0.11 0.45 1.65
54 INT24157 Binding of CALCA and SFTPA1 2 0.07 0.96 1.64
55 INT297489 Ryr2 Regulation of Positive_regulation of Ltp 1 0.05 0.16 1.64
56 INT122286 Prkaca Negative_regulation of Negative_regulation of Calca 1 0.12 0.54 1.63
57 INT160578 Binding of CALCA and TAC1 1 0.07 0.91 1.61
58 INT148935 Ramp1 Regulation of Calca 1 0.27 0.69 1.56
59 INT13968 Calca Negative_regulation of Positive_regulation of Sst 1 0.34 0 1.55
60 INT13970 Positive_regulation of Calca Positive_regulation of Sst 1 0.37 0 1.53
61 INT13965 Calca Positive_regulation of Positive_regulation of Sst 1 0.37 0 1.53
62 INT96784 Binding of CALCA and Calca 3 0.23 0.27 1.47
63 INT180791 Negative_regulation of Gdnf Regulation of Calca 1 0.17 0 1.47
64 INT180767 Bdnf Positive_regulation of Gene_expression of Calca 1 0.17 0 1.45
65 INT276681 Calca Regulation of Nav1 1 0.07 0.74 1.45
66 INT276686 Calca Regulation of Nav1 1 0.26 0.74 1.45
67 INT84434 Calca Negative_regulation of Negative_regulation of Hrh1 1 0.06 0.19 1.44
68 INT95325 HTR1B Negative_regulation of Calca 1 0.47 0.69 1.43
69 INT134760 Ghrl Regulation of Transcription of Calca 1 0.24 2.71 1.42
70 INT144122 Binding of Calca and P2rx6 1 0.10 0 1.4
71 INT169163 Binding of Calca and Ctbs 1 0.00 0.51 1.4
72 INT51213 Vip Regulation of Localization of Calca 1 0.38 0 1.39
73 INT8719 Npy Negative_regulation of Localization of Calca 1 0.06 0.26 1.39
74 INT168724 Creb1 Negative_regulation of Gene_expression of Calca 1 0.46 1.09 1.38
75 INT168721 Positive_regulation of Creb1 Positive_regulation of Calca 1 0.53 1.07 1.37
76 INT279165 Calca Regulation of Gene_expression of Fdft1 1 0.02 0.41 1.37
77 INT180810 Gopc Positive_regulation of Calca 1 0.02 0.28 1.36
78 INT168722 Creb1 Positive_regulation of Calca 1 0.73 1.05 1.35
79 INT151771 Binding of P2RX3 and Calca 1 0.04 0.89 1.34
80 INT298455 Calca Positive_regulation of Gene_expression of Ceacam3 1 0.17 0.47 1.34
81 INT180786 Calca Regulation of Positive_regulation of Ngf 1 0.40 0 1.32
82 INT136603 Calca Positive_regulation of Localization of Il6 1 0.67 0.78 1.32
83 INT180764 Calca Regulation of Positive_regulation of Gdnf 1 0.21 0 1.32
84 INT180807 Calca Regulation of Sorbs1 1 0.02 0 1.32
85 INT180771 Calca Regulation of Positive_regulation of Bdnf 1 0.18 0 1.32
86 INT121096 Binding of Calca and Trpv1 3 0.37 1.23 1.29
87 INT148775 Binding of Calca and Usf1 1 0.43 0.85 1.29
88 INT194408 Regulation of Binding of CALCA and DCLK3 1 0.15 0 1.29
89 INT138210 Mzb1 Regulation of Calca 1 0.25 0.41 1.29
90 INT168866 Binding of RYR1 and Cd38 1 0.02 0.17 1.28
91 INT22501 Binding of Calca and Pth 1 0.21 0.07 1.28
92 INT128776 Cntn1 Positive_regulation of Gene_expression of Pde6b 1 0.02 0.55 1.26
93 INT88635 Ptger3 Positive_regulation of Localization of Calca 2 0.05 0 1.24
94 INT103031 Calca Positive_regulation of Ptgs1 2 0.46 0.98 1.22
95 INT151454 Binding of Calca and Insrr 1 0.02 0.31 1.22
96 INT87586 RPL7AP5 Negative_regulation of Gene_expression of Calca 1 0.00 0.05 1.21
97 INT79471 Mgat4a Regulation of Calca 1 0.06 1.09 1.21
98 INT87585 RPL7AP5 Negative_regulation of Calca 1 0.00 0.05 1.21
99 INT124874 Gnat3 Positive_regulation of Localization of Calca 2 0.08 0.75 1.2
100 INT116730 Rac1 Regulation of Localization of Calca 1 0.13 1.32 1.19
101 INT152428 Ghrh Positive_regulation of Pde6b 1 0.07 0.5 1.18
102 INT194403 Negative_regulation of Binding of CALCA and DCLK3 1 0.22 0 1.18
103 INT207116 F2 Positive_regulation of F2r 5 0.12 2.16 1.16
104 INT338053 F2r Positive_regulation of Localization of Calca 1 0.06 0.47 1.15
105 INT91394 Negative_regulation of MMP2 Positive_regulation of CALCA 1 0.25 0.15 1.15
106 INT141979 Calca Negative_regulation of Gene_expression of Il1b 1 0.40 0.62 1.13
107 INT22176 Calca Regulation of Localization of Prl 4 0.69 0.39 1.11
108 INT4752 Gal Negative_regulation of Localization of Calca 1 0.41 0.06 1.11
109 INT282065 Binding of Calca and Ngf 1 0.14 0.85 1.11
110 INT4753 Sst Negative_regulation of Localization of Calca 1 0.39 0.06 1.1
111 INT70495 CALCA Positive_regulation of CALCB 2 0.40 0 1.08
112 INT352453 Calca Positive_regulation of Trib3 1 0.00 0.8 1.08
113 INT69889 Ngf Regulation of Localization of Calca 1 0.49 0.1 1.08
114 INT352468 Calca Positive_regulation of Prkaca 1 0.11 0.8 1.08
115 INT91395 MMP2 Positive_regulation of CALCA 1 0.36 0.17 1.07
116 INT79372 Calca Regulation of Pnoc 1 0.34 0 1.07
117 INT10238 Binding of EDN1 and Calca 1 0.00 1.07 1.06
118 INT139225 Calca Negative_regulation of Icam1 1 0.44 1.13 1.06
119 INT139229 Calca Negative_regulation of Cmklr1 1 0.19 1.12 1.06
120 INT139231 Calca Negative_regulation of Timp1 1 0.36 1.11 1.05
121 INT139226 Icam1 Negative_regulation of Calca 1 0.44 1.12 1.05
122 INT48260 Binding of Adcyap1 and Calca 1 0.35 0 1.04
123 INT130167 Trpv1 Regulation of Localization of Calca 2 0.38 0.69 1.03
124 INT86073 Med15 Regulation of Calca 1 0.49 0.2 1.03
125 INT114555 Binding of Calca and St3gal3 1 0.01 0.44 1.03
126 INT114552 Binding of Calca and Col4a4 1 0.01 0.44 1.02
127 INT51260 Calca Negative_regulation of Nts 1 0.10 0.08 1.01
128 INT51261 Calca Negative_regulation of Sst 1 0.20 0.08 1.01
129 INT298298 Calca Negative_regulation of Gene_expression of Runx1 1 0.19 0.33 1
130 INT112163 Calca Positive_regulation of Mpo 1 0.49 1.23 1
131 INT298274 Gene_expression of Runx1 Negative_regulation of Calca 1 0.19 0.33 1
132 INT162299 Negative_regulation of Adarb1 Negative_regulation of Gene_expression of Calca 1 0.01 0.93 1
133 INT195668 Binding of F2 and THBD 7 0.08 5.67 0.98
134 INT49163 Binding of Pax3 and Calca 1 0.03 0.37 0.98
135 INT24395 Binding of CALCA and CLPP 1 0.03 0.17 0.96
136 INT206857 Binding of Calca and Calcrl 4 0.37 1.9 0.95
137 INT148772 Usf1 Regulation of Calca 1 0.40 0.69 0.95
138 INT180787 Calca Regulation of Gdnf 1 0.18 0.28 0.95
139 INT352447 Gse1 Negative_regulation of Gene_expression of Calca 1 0.03 0.98 0.94
140 INT24938 TAC1 Regulation of Calca 1 0.22 0.35 0.94
141 INT24939 TAC3 Regulation of Calca 1 0.01 0.35 0.94
142 INT331109 Tpnr1 Regulation of Gene_expression of Calca 1 0.06 0.97 0.94
143 INT248186 Cxcl1 Positive_regulation of Localization of CALCA 1 0.39 0.88 0.93
144 INT107001 F2 Positive_regulation of PAR1 4 0.05 2.15 0.92
145 INT138602 Negative_regulation of BCL2L2 Positive_regulation of F2 1 0.00 0.67 0.92
146 INT55564 Binding of Oprk1 and Pde6b 1 0.01 0 0.92
147 INT28656 Calca Negative_regulation of Localization of Gnrhr 1 0.19 0 0.91
148 INT138601 BCL2L2 Positive_regulation of F2 1 0.00 0.66 0.91
149 INT169469 Binding of Egfr and Tgfa 1 0.19 1.87 0.91
150 INT53155 Rac1 Positive_regulation of Gene_expression of Calca 1 0.06 0 0.89
151 INT63943 Il1b Positive_regulation of Localization of Calca 2 0.46 0.98 0.88
152 INT53153 fut10 Positive_regulation of Gene_expression of Calca 1 0.01 0 0.88
153 INT28655 Calca Negative_regulation of Localization of Gh1 1 0.34 0 0.88
154 INT151779 Calca Positive_regulation of Transcription of P2rx7 1 0.02 0.54 0.87
155 INT213976 Calca Negative_regulation of Gene_expression of Il2 1 0.03 0.25 0.86
156 INT113542 Binding of Calca and Adarb1 2 0.00 0.44 0.85
157 INT351323 Nts Regulation of Localization of Calca 1 0.01 0.6 0.85
158 INT28654 Calca Regulation of Localization of Gh1 1 0.36 0 0.84
159 INT342991 HCL1 Positive_regulation of CALCA 1 0.03 0.71 0.84
160 INT111363 TRPV1 Positive_regulation of Localization of Calca 1 0.11 0 0.83
161 INT225691 TRPV1 Positive_regulation of Localization of CALCA 1 0.18 0.7 0.83
162 INT87490 CALCA Positive_regulation of Gene_expression of CCL5 1 0.30 0.14 0.81
163 INT103178 Mastl Positive_regulation of Localization of Calca 1 0.13 0.36 0.81
164 INT87494 CALCA Positive_regulation of IL8 1 0.48 0.15 0.81
165 INT86150 Inhba Positive_regulation of Gene_expression of Calca 1 0.09 0.61 0.81
166 INT87489 CALCA Positive_regulation of Gene_expression of CCL2 1 0.43 0.14 0.81
167 INT87492 CALCA Regulation of IL8 1 0.28 0.15 0.81
168 INT213972 Calca Regulation of Mthfd1 1 0.05 0.19 0.8
169 INT109142 Calca Positive_regulation of Transcription of Creb1 1 0.47 0.13 0.8
170 INT118010 Binding of CALCA and CD177 1 0.06 0.6 0.8
171 INT131646 Ngf Positive_regulation of Localization of Calca 1 0.21 0.35 0.8
172 INT180782 Bdnf Positive_regulation of Calca 1 0.16 0.77 0.8
173 INT86151 Olr1745 Positive_regulation of Gene_expression of Calca 1 0.51 0.6 0.8
174 INT60102 Adora1 Regulation of Localization of Calca 1 0.46 0 0.79
175 INT111361 Cnr1 Negative_regulation of Localization of Calca 1 0.01 0 0.78
176 INT298457 Binding of Calca and Npr1 1 0.01 0.39 0.77
177 INT96783 Positive_regulation of Binding of CALCA and Calca 1 0.29 0.17 0.77
178 INT224283 Bdnf Regulation of Gene_expression of Calca 1 0.19 0.35 0.76
179 INT87493 Binding of CALCA and Positive_regulation of Gene_expression of IL8 1 0.52 0.18 0.76
180 INT109141 Calca Positive_regulation of Creb1 1 0.47 0.13 0.76
181 INT262563 Negative_regulation of Pax3 Regulation of Calca 1 0.01 0.75 0.76
182 INT65593 CALCA Negative_regulation of Positive_regulation of ADCY1 1 0.23 0.07 0.76
183 INT109143 Calca Positive_regulation of Phosphorylation of Creb1 1 0.47 0.13 0.76
184 INT125626 Binding of Calca and Atp8a2 1 0.00 0.4 0.76
185 INT262569 Pax3 Regulation of Calca 1 0.00 0.75 0.76
186 INT147619 Npr1 Positive_regulation of Localization of Calca 1 0.03 0 0.75
187 INT127876 ACE Positive_regulation of Protein_catabolism of CALCA 1 0.28 0.63 0.75
188 INT262578 Prkaca Positive_regulation of Localization of Calca 1 0.03 0.71 0.75
189 INT147620 Gpi Positive_regulation of Localization of Calca 1 0.10 0 0.75
190 INT147278 Negative_regulation of Calca Positive_regulation of Th 1 0.41 0.76 0.74
191 INT147277 Calca Positive_regulation of Th 1 0.48 0.76 0.74
192 INT63874 Calca Positive_regulation of SRPX 1 0.01 0.17 0.74
193 INT142507 Binding of Calca and Ramp1 1 0.31 0.48 0.73
194 INT145592 Vamp1 Positive_regulation of Calca 1 0.01 0.28 0.73
195 INT106999 F2 Positive_regulation of PAR4 3 0.06 1.83 0.72
196 INT106992 F2 Positive_regulation of PARD3 3 0.05 1.83 0.72
197 INT180773 Calca Regulation of Binding of Gdnf 1 0.18 0.15 0.72
198 INT180769 Calca Regulation of Binding of Ngf 1 0.40 0.15 0.72
199 INT180765 Calca Regulation of Binding of Bdnf 1 0.15 0.15 0.72
200 INT68211 Binding of Calca and Chat 1 0.37 0 0.71

Single Events

The table below shows the top 100 pain related interactions that have been reported for cytosolic calcium ion homeostasis. They are ordered first by their pain relevance and then by number of times they were reported in cytosolic calcium ion homeostasis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT2542 Localization of Calca 2008 0.81 518.3 1408.65
2 INT1912 Gene_expression of Calca 1152 0.78 453.25 739.84
3 INT2543 Positive_regulation of Calca 787 0.70 331.13 592.08
4 INT4758 Positive_regulation of Localization of Calca 557 0.70 138.55 411.04
5 INT2540 Negative_regulation of Calca 538 0.59 172.11 384.38
6 INT2649 Regulation of Calca 433 0.62 146.05 330.95
7 INT4759 Negative_regulation of Localization of Calca 294 0.59 82.62 226.45
8 INT626 Localization of CALCA 289 0.81 125.39 221.15
9 INT5050 Regulation of Localization of Calca 149 0.62 41.25 148.57
10 INT3300 Positive_regulation of Gene_expression of Calca 179 0.70 77.76 144.2
11 INT2867 Gene_expression of CALCA 247 0.78 78.78 138.47
12 INT2541 Binding of Calca 200 0.48 67.14 134.62
13 INT5008 Localization of Calca 204 0.81 80.35 125.16
14 INT5010 Gene_expression of Calca 197 0.78 85.76 118.75
15 INT4860 Positive_regulation of CALCA 148 0.00 73.35 97.61
16 INT5780 Regulation of Gene_expression of Calca 90 0.62 59.52 85.03
17 INT6761 Binding of CALCA 100 0.48 26.71 62.05
18 INT4760 Negative_regulation of Gene_expression of Calca 93 0.59 34.19 60.3
19 INT4241 Regulation of CALCA 87 0.62 28.19 55.29
20 INT4891 Transcription of Calca 81 0.72 35.27 53.75
21 INT8700 Positive_regulation of Positive_regulation of Calca 56 0.67 21.69 53.66
22 INT97674 Positive_regulation of Localization of Calca 70 0.69 27.71 51.79
23 INT8490 Negative_regulation of CALCA 87 0.59 29.73 51.34
24 INT11406 Positive_regulation of Localization of CALCA 49 0.70 20.64 42.8
25 INT28265 Positive_regulation of Calca 62 0.70 29.1 41.17
26 INT8784 Negative_regulation of Positive_regulation of Calca 40 0.59 14.67 33.49
27 INT8746 Negative_regulation of Calca 50 0.59 21.22 33.45
28 INT23463 Positive_regulation of Gene_expression of CALCA 47 0.70 18.14 28.76
29 INT22499 Regulation of Calca 42 0.62 17.32 28.02
30 INT8358 Negative_regulation of Localization of CALCA 25 0.59 11.79 21.51
31 INT35998 Positive_regulation of Gene_expression of Calca 31 0.70 16.16 16.98
32 INT6150 Positive_regulation of Negative_regulation of Calca 20 0.68 4.06 16.26
33 INT65109 Negative_regulation of Transcription of Calca 16 0.59 8.63 12.84
34 INT2129 Positive_regulation of F2 83 0.70 58.95 12.63
35 INT26217 Binding of Calca 22 0.48 5.22 12.57
36 INT11244 Transcription of CALCA 21 0.69 3.61 12.27
37 INT15136 Regulation of Positive_regulation of Calca 12 0.62 3.02 12.16
38 INT6151 Negative_regulation of Negative_regulation of Calca 14 0.58 4.86 11.81
39 INT86698 Gene_expression of Cav1 38 0.78 16.37 11.75
40 INT127981 Gene_expression of Trpc1 25 0.77 10.51 11.67
41 INT1190 Positive_regulation of F2 53 0.70 46.41 11.64
42 INT48009 Gene_expression of Pde6b 38 0.68 15.03 11.41
43 INT5779 Positive_regulation of Transcription of Calca 15 0.62 5.61 10.86
44 INT4498 Gene_expression of F2 83 0.65 57.4 10.8
45 INT101203 Negative_regulation of Gene_expression of Calca 12 0.59 7.06 10.72
46 INT103251 Negative_regulation of Localization of Calca 13 0.43 9.36 8.86
47 INT8761 Negative_regulation of Binding of Calca 12 0.43 3.59 8.32
48 INT2271 Gene_expression of F2 51 0.76 30.21 7.97
49 INT17501 Negative_regulation of F2 70 0.58 32.23 7.51
50 INT25220 Positive_regulation of Binding of Calca 7 0.69 3.78 7.34
51 INT124264 Regulation of Localization of Calca 10 0.33 1.39 7.14
52 INT717 Regulation of F2 29 0.61 17.46 6.99
53 INT1038 Negative_regulation of F2 26 0.58 15.12 6.75
54 INT52813 Regulation of Localization of CALCA 8 0.62 3.16 5.89
55 INT86982 Transcription of Calca 9 0.69 2.98 5.74
56 INT22839 Gene_expression of F2 31 0.74 15.53 5.56
57 INT5778 Regulation of Transcription of Calca 4 0.45 2.47 5.37
58 INT14715 Negative_regulation of Positive_regulation of CALCA 5 0.43 2.22 5.2
59 INT20650 Positive_regulation of F2 26 0.69 15.49 5.08
60 INT27261 Regulation of Regulation of Calca 7 0.45 2.8 5.08
61 INT37148 Negative_regulation of Gene_expression of CALCA 7 0.43 1.91 4.98
62 INT59555 Binding of RYR1 39 0.42 8.65 4.92
63 INT52251 Negative_regulation of Binding of CALCA 3 0.41 0.57 4.71
64 INT54987 Regulation of Gene_expression of Calca 6 0.62 3.44 4.59
65 INT9842 Binding of F2 36 0.47 22.79 4.42
66 INT119498 Positive_regulation of Pde6b 11 0.43 18.75 4.22
67 INT48008 Negative_regulation of Pde6b 9 0.15 6.12 4.11
68 INT141443 Phosphorylation of Cav1 6 0.82 4.39 4.03
69 INT153666 Gene_expression of CAV1 156 0.77 120.99 3.9
70 INT24677 Regulation of Negative_regulation of Calca 6 0.44 0.73 3.9
71 INT132700 Positive_regulation of Trpc1 6 0.39 4.33 3.89
72 INT28802 Binding of F2 15 0.47 8.8 3.47
73 INT63506 Localization of F2 21 0.77 7.53 3.41
74 INT15648 Positive_regulation of RYR1 30 0.67 12.03 3.26
75 INT131978 Gene_expression of Trpc1 15 0.71 4.67 3.19
76 INT26273 Negative_regulation of RYR1 18 0.43 7.64 3.11
77 INT51151 Positive_regulation of Regulation of Calca 8 0.50 1.77 3.08
78 INT201152 Regulation of Ryr2 5 0.32 2.8 2.99
79 INT27146 Negative_regulation of Regulation of Calca 4 0.43 1.18 2.9
80 INT60672 Regulation of Gene_expression of CALCA 3 0.61 1.76 2.85
81 INT95720 Phosphorylation of Calca 2 0.80 2.04 2.8
82 INT57354 Positive_regulation of Positive_regulation of Calca 3 0.60 1.42 2.78
83 INT8840 Positive_regulation of Positive_regulation of CALCA 8 0.50 1.8 2.74
84 INT86703 Positive_regulation of Gene_expression of Cav1 7 0.70 3.58 2.73
85 INT14447 Localization of F2 20 0.79 12.77 2.67
86 INT71933 Positive_regulation of Gene_expression of F2 19 0.56 14.24 2.53
87 INT19292 Protein_catabolism of CALCA 7 0.76 0.8 2.53
88 INT128773 Regulation of Gene_expression of Pde6b 4 0.45 1.41 2.5
89 INT86134 Gene_expression of Ptgdr 9 0.46 3.45 2.47
90 INT136614 Positive_regulation of Cav1 5 0.46 2.28 2.23
91 INT63505 Negative_regulation of F2 18 0.57 7.4 2.2
92 INT48007 Regulation of Pde6b 6 0.39 4.4 2.2
93 INT58752 Positive_regulation of Binding of CALCA 3 0.49 0.73 2.09
94 INT152902 Positive_regulation of Transcription of CALCA 5 0.66 0.99 2.07
95 INT6508 Gene_expression of RYR1 34 0.77 11.11 2.04
96 INT54986 Negative_regulation of Positive_regulation of Calca 2 0.43 0.93 2.02
97 INT112089 Gene_expression of Cav1 73 0.75 23.8 1.97
98 INT24291 Positive_regulation of Negative_regulation of CALCA 3 0.61 0.67 1.91
99 INT141444 Positive_regulation of Phosphorylation of Cav1 1 0.70 1.76 1.69
100 INT11713 Localization of RYR1 22 0.76 10.42 1.64
101 INT241566 Negative_regulation of Negative_regulation of Calca 1 0.03 0.72 1.63
102 INT88667 Negative_regulation of Gene_expression of F2 11 0.41 5.53 1.62
103 INT135955 Positive_regulation of Cav1 17 0.48 7.73 1.61
104 INT53273 Positive_regulation of Ptgdr 3 0.14 1.34 1.52
105 INT22836 Regulation of F2 9 0.59 2.3 1.49
106 INT48300 Regulation of Binding of Calca 2 0.39 0.73 1.49
107 INT12035 Regulation of F2 21 0.45 12.66 1.47
108 INT145127 Positive_regulation of Gene_expression of Trpc1 4 0.30 3.56 1.46
109 INT52250 Positive_regulation of Regulation of CALCA 1 0.48 0.08 1.43
110 INT39444 Negative_regulation of Positive_regulation of F2 7 0.59 5.82 1.42
111 INT259086 Binding of Trpc1 3 0.22 1.27 1.37
112 INT78097 Negative_regulation of Regulation of CALCA 2 0.42 2.02 1.37
113 INT55305 Regulation of RYR1 14 0.45 5.27 1.33
114 INT27656 Gene_expression of Tgfa 6 0.74 3.37 1.32
115 INT36337 Localization of Tgfa 4 0.73 0.83 1.32
116 INT36588 Protein_catabolism of Calca 7 0.87 1.98 1.31
117 INT39634 Regulation of Gene_expression of F2 4 0.22 1.72 1.31
118 INT39443 Positive_regulation of Positive_regulation of F2 6 0.70 4.31 1.3
119 INT152486 Positive_regulation of Gene_expression of Trpc1 2 0.41 0.89 1.29
120 INT138085 Regulation of Trpc1 2 0.32 0.53 1.28
121 INT2270 Positive_regulation of Gene_expression of F2 6 0.21 4.23 1.26
122 INT138084 Localization of Trpc1 4 0.79 0.2 1.26
123 INT141862 Binding of Cav1 11 0.36 1.32 1.25
124 INT138343 Positive_regulation of Localization of F2 5 0.41 5.06 1.24
125 INT114568 Negative_regulation of Trpc1 4 0.41 0.56 1.19
126 INT102615 Positive_regulation of Gene_expression of Tgfa 5 0.44 3.93 1.17
127 INT152487 Positive_regulation of Trpc1 2 0.38 0.85 1.17
128 INT139764 Negative_regulation of CAV1 10 0.58 6.57 1.14
129 INT127427 Negative_regulation of Ptgdr 1 0.17 1.66 1.12
130 INT259087 Negative_regulation of Binding of Trpc1 1 0.17 1.04 1.05
131 INT174273 Positive_regulation of Binding of F2 3 0.08 2.99 1.02
132 INT95719 Negative_regulation of Phosphorylation of Calca 1 0.41 0.09 1.02
133 INT95718 Positive_regulation of Phosphorylation of Calca 1 0.49 0.09 1.01
134 INT138467 Gene_expression of Ryr2 5 0.55 2.36 0.98
135 INT136613 Negative_regulation of Cav1 2 0.57 2.28 0.96
136 INT153670 Positive_regulation of Gene_expression of CAV1 26 0.69 44.27 0.92
137 INT141442 Negative_regulation of Phosphorylation of Cav1 1 0.59 0.94 0.87
138 INT24327 Gene_expression of Tgfa 6 0.64 3.61 0.86
139 INT54985 Positive_regulation of Regulation of Calca 2 0.47 0.33 0.86
140 INT196322 Binding of F2 18 0.15 7.74 0.83
141 INT97673 Protein_catabolism of Calca 1 0.50 0.15 0.82
142 INT77295 Positive_regulation of Tgfa 2 0.34 0.05 0.8
143 INT112090 Negative_regulation of Gene_expression of Cav1 8 0.57 3.5 0.78
144 INT130057 Positive_regulation of CAV1 12 0.65 8.96 0.77
145 INT138606 Negative_regulation of Positive_regulation of F2 2 0.12 0.54 0.74
146 INT112088 Regulation of Cav1 2 0.44 0.51 0.73
147 INT201165 Localization of Ryr2 6 0.64 3.54 0.71
148 INT277207 Regulation of Ptgdr 1 0.08 1.17 0.7
149 INT153667 Localization of CAV1 15 0.76 11.92 0.68
150 INT277205 Localization of Ptgdr 2 0.22 1.74 0.65
151 INT168000 Protein_catabolism of F2 6 0.63 2.19 0.63
152 INT72911 Positive_regulation of Negative_regulation of Calca 1 0.43 0.07 0.63
153 INT251632 Positive_regulation of Cdh23 1 0.00 0.27 0.63
154 INT221935 Gene_expression of TRPC1 5 0.45 0.53 0.62
155 INT86700 Regulation of Cav1 7 0.54 0.92 0.61
156 INT131001 Regulation of CAV1 6 0.44 3.77 0.59
157 INT69098 Positive_regulation of Gene_expression of F2 5 0.66 3.79 0.58
158 INT141863 Negative_regulation of Gene_expression of Cav1 4 0.49 1.77 0.58
159 INT98932 Positive_regulation of Negative_regulation of F2 1 0.04 1.06 0.58
160 INT149350 Regulation of Gene_expression of Trpc1 1 0.19 1.13 0.57
161 INT104877 Positive_regulation of Positive_regulation of Ptgdr 1 0.08 0.15 0.56
162 INT126754 Binding of Pde6b 5 0.34 1.34 0.55
163 INT59481 Negative_regulation of Negative_regulation of CALCA 2 0.43 0.08 0.54
164 INT94088 Transcription of Pde6b 2 0.55 0.39 0.53
165 INT180459 Gene_expression of Cdh23 4 0.14 5.11 0.52
166 INT59386 Binding of Tgfa 2 0.06 0.41 0.52
167 INT320172 Negative_regulation of Binding of F2 2 0.41 1.92 0.5
168 INT86702 Localization of Cav1 8 0.69 0.76 0.47
169 INT195092 Protein_catabolism of F2 4 0.26 2.75 0.47
170 INT152425 Positive_regulation of Positive_regulation of Pde6b 2 0.18 1.74 0.46
171 INT153672 Negative_regulation of Negative_regulation of CAV1 1 0.25 0.2 0.46
172 INT53282 Negative_regulation of Atp2b2 4 0.15 2.6 0.45
173 INT67179 Negative_regulation of Binding of F2 3 0.41 2.23 0.45
174 INT15647 Regulation of Positive_regulation of RYR1 1 0.26 0.23 0.45
175 INT192006 Gene_expression of RYR2 5 0.23 7.69 0.44
176 INT220504 Positive_regulation of Gene_expression of Cav1 11 0.39 6.26 0.43
177 INT166240 Regulation of Gene_expression of Cav1 3 0.51 1.03 0.43
178 INT119499 Regulation of Positive_regulation of Pde6b 2 0.11 0.8 0.43
179 INT140496 Positive_regulation of TRPC1 3 0.29 0.43 0.42
180 INT138466 Regulation of Gene_expression of Ryr2 3 0.28 1.62 0.39
181 INT162049 Phosphorylation of F2 3 0.47 0.99 0.39
182 INT69104 Positive_regulation of Localization of F2 2 0.66 0.06 0.39
183 INT165349 Positive_regulation of Positive_regulation of Trpc1 1 0.39 0.74 0.39
184 INT220506 Binding of Cav1 13 0.45 5.46 0.38
185 INT69865 Binding of Ptgdr 2 0.08 1.25 0.38
186 INT69103 Negative_regulation of Localization of F2 2 0.56 0.48 0.37
187 INT135953 Negative_regulation of Positive_regulation of Cav1 2 0.37 1.09 0.37
188 INT161436 Transcription of F2 2 0.69 1.21 0.36
189 INT242545 Regulation of Regulation of Calca 1 0.15 0 0.36
190 INT233109 Regulation of Positive_regulation of CALCA 1 0.30 0.23 0.36
191 INT163277 Negative_regulation of Gene_expression of CAV1 17 0.56 10.77 0.35
192 INT180456 Regulation of Cdh23 3 0.06 2.83 0.32
193 INT138468 Negative_regulation of Gene_expression of Ryr2 1 0.17 0.25 0.32
194 INT162051 Positive_regulation of Phosphorylation of F2 1 0.29 0.99 0.3
195 INT77294 Regulation of Gene_expression of Tgfa 1 0.59 0.27 0.3
196 INT201149 Positive_regulation of Ryr2 7 0.42 5.31 0.29
197 INT141867 Positive_regulation of Transcription of Cav1 2 0.52 0.46 0.29
198 INT141868 Transcription of Cav1 2 0.54 1.48 0.29
199 INT80636 Positive_regulation of Localization of RYR1 2 0.47 0.78 0.29
200 INT105246 Negative_regulation of Tgfa 1 0.07 1.08 0.29
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