GO:0051495

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Name positive regulation of cytoskeleton organization
Categary Process
Go Slim No
Go Link GO:0051495
Unique Molecular Interactions 69
Total Molecular Interactions 81
Total Single Events 893
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of cytoskeleton organization. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of cytoskeleton organization. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT96906 Plxna3 Regulation of Regulation of Prkaca 1 0.17 0.71 1.08
2 INT96905 Plxna3 Regulation of Regulation of Prkce 1 0.18 0.71 1.07
3 INT151779 Calca Positive_regulation of Transcription of P2rx7 1 0.02 0.54 0.87
4 INT215598 Positive_regulation of P2rx7 Positive_regulation of Localization of TNF 1 0.22 1.44 0.85
5 INT67908 Binding of Cck and Plxna3 1 0.04 0.54 0.84
6 INT281241 Positive_regulation of P2RX7 Negative_regulation of Gene_expression of P2rx3 1 0.03 0.79 0.71
7 INT205706 P2rx7 Regulation of Gene_expression of Il18 1 0.21 1.35 0.7
8 INT246335 Fig4 Regulation of Localization of P2rx7 1 0.01 0 0.67
9 INT205702 P2rx7 Regulation of Gene_expression of Il1 1 0.04 1.38 0.67
10 INT205705 Positive_regulation of P2rx7 Positive_regulation of Gene_expression of Il6 1 0.07 1.42 0.58
11 INT308174 Binding of TNF and P2rx7 1 0.02 0.84 0.56
12 INT282821 TACR1 Regulation of P2RX7 1 0.01 2.06 0.54
13 INT185490 Atp5o Negative_regulation of Gene_expression of P2rx7 1 0.01 0.87 0.53
14 INT216941 P2rx7 Regulation of Ryr1 1 0.01 0.55 0.52
15 INT278122 Negative_regulation of P2rx7 Negative_regulation of Binding of P2RX7 1 0.03 0 0.51
16 INT278105 Negative_regulation of TP63 Negative_regulation of Binding of P2RX7 1 0.00 0 0.51
17 INT146276 Binding of P2RX4 and P2RX7 1 0.38 0.38 0.43
18 INT169859 P2rx7 Regulation of Gene_expression of Grin1 1 0.17 0 0.43
19 INT322015 Binding of IL1B and P2RX7 1 0.07 1 0.37
20 INT205704 P2rx7 Regulation of Localization of Il18 1 0.09 0.67 0.35
21 INT191128 Positive_regulation of P2RX7 Positive_regulation of Localization of Il1b 1 0.02 0.71 0.34
22 INT217041 TNF Positive_regulation of Gene_expression of P2RX7 1 0.50 0.81 0.34
23 INT205713 Positive_regulation of P2rx7 Positive_regulation of Gene_expression of IL8 1 0.03 0.77 0.33
24 INT217025 P2rx7 Regulation of Gene_expression of Ik 1 0.00 0.25 0.33
25 INT217024 Regulation of P2rx7 Regulation of Gene_expression of Ik 1 0.00 0.25 0.33
26 INT205703 P2rx7 Regulation of Positive_regulation of Casp1 1 0.11 0.66 0.33
27 INT205711 P2rx7 Regulation of Localization of IL8 1 0.02 0.92 0.33
28 INT145682 Binding of P2rx4 and P2rx7 2 0.25 0.36 0.31
29 INT215789 Fig4 Positive_regulation of Localization of P2rx7 1 0.03 0.53 0.29
30 INT158733 Esr1 Regulation of Plxna3 1 0.03 0.27 0.29
31 INT205701 P2rx7 Positive_regulation of Il1 1 0.04 0.8 0.25
32 INT185489 Atp5o Negative_regulation of P2rx7 1 0.01 0.29 0.24
33 INT216911 Positive_regulation of P2rx7 Positive_regulation of Localization of Plg 1 0.02 0.13 0.23
34 INT107219 Binding of P2rx7 and Atp5o 1 0.03 0.07 0.21
35 INT216946 P2rx7 Regulation of Il10 1 0.28 0.17 0.21
36 INT107223 APEH Negative_regulation of P2rx7 1 0.00 0.13 0.21
37 INT322011 BSG Regulation of P2RX7 1 0.00 0.48 0.21
38 INT205710 CAMP Positive_regulation of P2rx7 1 0.02 0.47 0.19
39 INT270827 P2rx7 Positive_regulation of Localization of Panx1 1 0.41 0.18 0.13
40 INT216945 Positive_regulation of P2rx7 Positive_regulation of Positive_regulation of Casp1 1 0.14 0.18 0.12
41 INT322037 Binding of P2RX7 and Myh1 1 0.06 0 0.12
42 INT74504 Binding of P2rx7 and Rp2 1 0.02 0.19 0.11
43 INT146997 Binding of PLXNA3 and RLS 1 0.36 0.47 0.1
44 INT205708 Binding of Icam1 and P2rx7 1 0.08 1.03 0.09
45 INT217036 IRF6 Positive_regulation of Gene_expression of P2rx7 1 0.02 0 0.09
46 INT270824 Binding of P2rx7 and Panx1 1 0.34 0.15 0.09
47 INT304464 Binding of P2rx7 and P2rx6 1 0.05 0 0.09
48 INT243156 Positive_regulation of P2rx7 Positive_regulation of NOS1 1 0.00 0.08 0.08
49 INT270829 P2rx7 Positive_regulation of Panx1 1 0.66 0.08 0.08
50 INT340420 Hmmr Regulation of P2rx7 1 0.01 1.12 0.08
51 INT270835 Positive_regulation of P2rx7 Positive_regulation of Localization of DPEP1 1 0.04 0.08 0.07
52 INT340427 Positive_regulation of P2rx7 Positive_regulation of Regulation of Pkhd1 1 0.01 1 0.05
53 INT270825 P2rx7 Positive_regulation of Slc37a4 1 0.01 0 0.04
54 INT353192 Stat5a Positive_regulation of Plxna3 1 0.01 0 0
55 INT353189 Plxna3 Negative_regulation of Cyp4a8 1 0.01 0.35 0
56 INT276285 Binding of SEPHS1 and PLXNA3 1 0.00 0.41 0
57 INT217031 Binding of P2rx7 and Positive_regulation of Casp1 1 0.02 0 0
58 INT311948 Binding of NRP1 and Plxna3 1 0.05 0.26 0
59 INT311947 Binding of SEMA3A and Plxna3 1 0.07 0.26 0
60 INT217032 Binding of P2rx7 and Positive_regulation of Il1 1 0.02 0 0
61 INT216942 Positive_regulation of P2rx7 Positive_regulation of Casp1 1 0.14 0 0
62 INT307460 P2rx7 Positive_regulation of Phosphorylation of Gsk3a 1 0.02 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of cytoskeleton organization. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of cytoskeleton organization. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT49519 Gene_expression of P2rx7 84 0.76 36.88 34.69
2 INT88327 Gene_expression of P2rx7 109 0.77 48.86 22.41
3 INT23787 Positive_regulation of P2rx7 36 0.68 23.54 19.45
4 INT127046 Gene_expression of P2RX7 65 0.78 34.28 14.76
5 INT121241 Positive_regulation of P2rx7 65 0.69 40.94 13.59
6 INT137980 Positive_regulation of P2RX7 30 0.67 22.49 10
7 INT73427 Localization of P2rx7 24 0.79 8.65 9.87
8 INT48257 Negative_regulation of P2rx7 18 0.41 7.82 8.42
9 INT88326 Negative_regulation of P2rx7 16 0.58 8.77 6.25
10 INT94608 Regulation of P2rx7 19 0.23 8.06 6.19
11 INT68882 Binding of P2rx7 16 0.23 4.33 6.17
12 INT145680 Regulation of P2rx7 22 0.61 11.92 5.42
13 INT32256 Gene_expression of PLXNA3 11 0.75 7.8 4.92
14 INT185484 Positive_regulation of Gene_expression of P2rx7 8 0.31 7.44 4.28
15 INT127047 Negative_regulation of P2RX7 10 0.39 7.17 4.01
16 INT144830 Positive_regulation of Gene_expression of P2rx7 22 0.68 9.78 3.92
17 INT129441 Regulation of Gene_expression of P2rx7 8 0.24 4.29 3.32
18 INT21156 Binding of PLXNA3 21 0.36 7.95 3.3
19 INT144828 Binding of P2rx7 19 0.47 7.84 3.16
20 INT191120 Regulation of P2RX7 8 0.41 5.29 2.96
21 INT137978 Localization of P2RX7 6 0.73 5.04 2.84
22 INT107216 Negative_regulation of Gene_expression of P2rx7 10 0.56 3.39 2.61
23 INT82347 Regulation of PLXNA3 5 0.60 4.59 2.45
24 INT137972 Binding of P2RX7 12 0.36 8.01 2.18
25 INT144829 Localization of P2rx7 12 0.79 2.92 2.12
26 INT64609 Negative_regulation of PLXNA3 5 0.57 3.64 1.94
27 INT216936 Negative_regulation of Gene_expression of P2rx7 5 0.42 2.59 1.84
28 INT141385 Positive_regulation of Gene_expression of P2RX7 7 0.62 3.95 1.73
29 INT16622 Positive_regulation of PLXNA3 6 0.67 5.2 1.69
30 INT174107 Binding of Plxna3 4 0.21 2.95 1.62
31 INT23786 Positive_regulation of Positive_regulation of P2rx7 5 0.44 2.21 1.58
32 INT125735 Transcription of P2rx7 3 0.62 1.34 1.58
33 INT215757 Transcription of P2rx7 3 0.21 1.84 1.45
34 INT205691 Regulation of Gene_expression of P2rx7 5 0.44 3.25 1.42
35 INT205690 Positive_regulation of Positive_regulation of P2rx7 14 0.68 6.26 1.3
36 INT216661 Regulation of Positive_regulation of P2rx7 1 0.07 0 1
37 INT191121 Regulation of Gene_expression of P2RX7 3 0.36 3.69 0.99
38 INT113887 Positive_regulation of Negative_regulation of P2rx7 1 0.22 1.02 0.96
39 INT104079 Gene_expression of Plxna3 4 0.65 0.86 0.94
40 INT215567 Positive_regulation of Positive_regulation of P2RX7 2 0.45 0.07 0.93
41 INT151776 Positive_regulation of Transcription of P2rx7 1 0.03 0.53 0.86
42 INT62760 Localization of PLXNA3 3 0.78 2.06 0.8
43 INT271589 Regulation of Transcription of P2rx7 1 0.05 0.5 0.78
44 INT278119 Positive_regulation of Localization of P2RX7 2 0.45 1.14 0.77
45 INT125734 Negative_regulation of Transcription of P2rx7 1 0.38 0.81 0.67
46 INT104078 Localization of Plxna3 1 0.78 0.36 0.64
47 INT185485 Negative_regulation of Localization of P2rx7 1 0.26 0.95 0.62
48 INT11847 Regulation of Plxna3 3 0.44 0.45 0.52
49 INT153099 Negative_regulation of Positive_regulation of P2rx7 1 0.42 0.25 0.5
50 INT215732 Negative_regulation of Binding of P2rx7 1 0.11 0.74 0.49
51 INT278114 Negative_regulation of Negative_regulation of P2rx7 1 0.21 0 0.45
52 INT215741 Positive_regulation of Transcription of P2rx7 1 0.15 1.15 0.43
53 INT217017 Transcription of P2RX7 1 0.27 0.36 0.39
54 INT46873 Positive_regulation of Plxna3 1 0.49 0 0.38
55 INT121239 Regulation of Positive_regulation of P2rx7 2 0.61 1.32 0.32
56 INT104082 Negative_regulation of Plxna3 1 0.41 0.19 0.32
57 INT104084 Negative_regulation of Localization of Plxna3 1 0.57 0.19 0.32
58 INT104080 Regulation of Localization of Plxna3 1 0.60 0.17 0.32
59 INT104083 Negative_regulation of Gene_expression of Plxna3 1 0.42 0.19 0.32
60 INT158730 Gene_expression of Plxna3 4 0.65 1.82 0.29
61 INT158728 Regulation of Gene_expression of Plxna3 1 0.44 0.28 0.29
62 INT158731 Positive_regulation of Gene_expression of Plxna3 1 0.49 0.28 0.29
63 INT216937 Regulation of Binding of P2rx7 1 0.44 0.08 0.29
64 INT146278 Negative_regulation of Gene_expression of P2RX7 2 0.42 0.21 0.25
65 INT322030 Regulation of Positive_regulation of P2RX7 1 0.41 0.55 0.24
66 INT216938 Negative_regulation of Localization of P2rx7 1 0.37 0.25 0.24
67 INT216940 Negative_regulation of Binding of P2rx7 1 0.37 0.15 0.2
68 INT227947 Regulation of Plxna3 1 0.07 0.2 0.19
69 INT216889 Phosphorylation of P2rx7 1 0.23 0 0.18
70 INT307467 Regulation of Binding of P2rx7 1 0.08 0 0.16
71 INT270813 Positive_regulation of Localization of P2rx7 1 0.46 0.24 0.15
72 INT322025 Positive_regulation of Binding of P2RX7 1 0.45 0 0.1
73 INT307481 Phosphorylation of P2rx7 1 0.15 0.35 0.08
74 INT307480 Positive_regulation of Phosphorylation of P2rx7 1 0.09 0.35 0.08
75 INT351575 Negative_regulation of Positive_regulation of P2RX7 1 0.41 1.81 0.04
76 INT224008 Regulation of Localization of P2RX7 1 0.22 0.74 0.03
77 INT353172 Negative_regulation of Plxna3 1 0.01 0.14 0
78 INT311924 Transcription of Plxna3 1 0.10 0 0
79 INT296201 Binding of Plxna3 1 0.36 0.08 0
80 INT188898 Negative_regulation of Localization of PLXNA3 1 0.09 0.47 0
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