GO:0051527

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Name NFAT2 protein binding
Categary Function
Go Slim No
Go Link GO:0051527
Unique Molecular Interactions 55
Total Molecular Interactions 67
Total Single Events 483
Pain Genes Associated 2

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for NFAT2 protein binding. They are ordered first by their pain relevance and then by number of times they were reported for NFAT2 protein binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT139724 PROC Positive_regulation of MAPK14 1 0.00 1.57 1.25
2 INT330379 Gene_expression of IL10 Negative_regulation of Positive_regulation of MAPK14 1 0.00 1.95 1.18
3 INT209928 IL1B Positive_regulation of MAPK14 2 0.15 1.69 0.87
4 INT346234 MAP2K6 Positive_regulation of MAPK14 1 0.44 1.65 0.77
5 INT278694 TNF Positive_regulation of MAPK14 1 0.03 0.79 0.56
6 INT171906 MAPK1 Positive_regulation of Gene_expression of MAPK14 1 0.08 1.55 0.52
7 INT278964 MAPK14 Negative_regulation of Localization of EPHB2 1 0.15 0.47 0.43
8 INT278970 MAPK14 Positive_regulation of Gene_expression of IL8 1 0.11 0.66 0.37
9 INT278938 MAPK14 Positive_regulation of Gene_expression of PRKCA 1 0.05 0.65 0.37
10 INT278966 MAPK14 Positive_regulation of Gene_expression of LEP 1 0.16 0.62 0.36
11 INT346228 MAP2K6 Positive_regulation of Positive_regulation of MAPK14 1 0.44 0.68 0.34
12 INT346229 PREP Positive_regulation of MAPK14 1 0.13 0.63 0.34
13 INT346236 Binding of MAPK14 and MAP2K6 1 0.32 0.65 0.33
14 INT346231 Binding of MAPK14 and MAP2K3 1 0.33 0.65 0.33
15 INT297972 MAPK14 Negative_regulation of ING5 1 0.21 1.67 0.33
16 INT255944 MAPK14 Positive_regulation of Tauph 1 0.00 0.1 0.32
17 INT259639 MAPK14 Regulation of Gene_expression of IL8 1 0.02 1.2 0.32
18 INT255945 MAPK14 Positive_regulation of Rps6ka5 1 0.06 0.1 0.32
19 INT255946 MAPK14 Positive_regulation of Map3k1 1 0.04 0.1 0.32
20 INT346235 IL1B Positive_regulation of Gene_expression of MAPK14 1 0.15 0.64 0.32
21 INT112799 Positive_regulation of CASP1 Positive_regulation of MAPK14 1 0.02 0.16 0.3
22 INT242878 INS Negative_regulation of Gene_expression of SPI1 1 0.04 1.81 0.27
23 INT123663 F2R Positive_regulation of MAPK14 1 0.12 0.42 0.26
24 INT123662 Negative_regulation of F2R Positive_regulation of MAPK14 1 0.08 0.42 0.26
25 INT171907 MAPK8 Positive_regulation of Gene_expression of MAPK14 1 0.06 0.77 0.26
26 INT123661 COL7A1 Positive_regulation of MAPK14 1 0.08 0.42 0.26
27 INT171911 MAPK8IP3 Positive_regulation of Gene_expression of MAPK14 1 0.05 0.77 0.26
28 INT179230 Binding of MAPK14 and GSR 1 0.03 0.5 0.23
29 INT112794 CASP1 Positive_regulation of MAPK14 1 0.02 0.16 0.23
30 INT112793 IL4I1 Positive_regulation of Positive_regulation of MAPK14 1 0.04 0 0.22
31 INT297965 MAPK14 Negative_regulation of GADD45A 1 0.05 1 0.21
32 INT226518 Il1rl1 Positive_regulation of MAPK14 1 0.04 0.2 0.15
33 INT226520 Il1rl1 Positive_regulation of Gene_expression of MAPK14 1 0.03 0.2 0.15
34 INT295480 MAPK14 Positive_regulation of Localization of TNF 1 0.08 1.08 0.12
35 INT297967 MAPK14 Negative_regulation of SCUBE3 1 0.01 0.67 0.12
36 INT242881 SPI1 Negative_regulation of Regulation of TLR2 1 0.04 1.13 0.11
37 INT291260 Map3k8 Regulation of Gene_expression of MAPK14 1 0.07 0.52 0.11
38 INT242880 Binding of SPI1 and TLR4 1 0.03 0.24 0.07
39 INT182268 Negative_regulation of MAPK14 Negative_regulation of Gene_expression of EDN1 1 0.22 0.31 0.07
40 INT182274 MAPK14 Negative_regulation of Gene_expression of EDN1 1 0.22 0.31 0.07
41 INT140289 ROS1 Positive_regulation of MAPK14 1 0.44 1.27 0.06
42 INT164128 TNFSF10 Positive_regulation of MAPK14 1 0.28 2.09 0.05
43 INT182264 EDN1 Positive_regulation of Positive_regulation of MAPK14 1 0.26 0.1 0.05
44 INT237682 LDHA Positive_regulation of MAPK14 1 0.02 0.16 0.03
45 INT209927 MAPK14 Positive_regulation of IL1B 1 0.13 0.05 0.03
46 INT298002 Gene_expression of Gadd45b Positive_regulation of MAPK14 1 0.29 0.67 0.03
47 INT297962 MAP3K4 Positive_regulation of MAPK14 1 0.21 0.66 0.03
48 INT242884 INS Regulation of SPI1 1 0.03 0.3 0.03
49 INT242876 Negative_regulation of Binding of SPI1 and TLR4 1 0.04 0.05 0
50 INT350429 Negative_regulation of MAPK14 Regulation of Gene_expression of ATF3 1 0.12 0.78 0
51 INT209925 Binding of MAPK14 and IL1B 1 0.09 0 0
52 INT242879 Positive_regulation of Binding of SPI1 and TLR4 1 0.04 0.05 0
53 INT242885 Binding of POU2F1 and SPI1 1 0.01 0 0
54 INT194675 MAPK14 Positive_regulation of CREB1 1 0.07 0.33 0
55 INT194684 MAPK14 Positive_regulation of Transcription of CREB1 1 0.07 0.33 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for NFAT2 protein binding. They are ordered first by their pain relevance and then by number of times they were reported in NFAT2 protein binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT86534 Positive_regulation of MAPK14 81 0.62 57.81 23.62
2 INT69322 Negative_regulation of MAPK14 70 0.54 42.92 22.71
3 INT171924 Gene_expression of MAPK14 60 0.65 54.38 21.68
4 INT110178 Phosphorylation of MAPK14 40 0.68 19.38 10.37
5 INT117920 Regulation of MAPK14 14 0.38 8.75 4.31
6 INT117921 Positive_regulation of Positive_regulation of MAPK14 9 0.44 9.93 4.18
7 INT173179 Binding of MAPK14 13 0.29 4.51 2.92
8 INT110179 Negative_regulation of Phosphorylation of MAPK14 11 0.36 5.25 2.38
9 INT173647 Positive_regulation of Gene_expression of MAPK14 15 0.39 7.54 2.05
10 INT173173 Regulation of Positive_regulation of MAPK14 6 0.38 2.59 1.64
11 INT182297 Positive_regulation of Phosphorylation of MAPK14 7 0.42 3.36 1.53
12 INT173654 Localization of MAPK14 12 0.62 3.16 1.43
13 INT112823 Negative_regulation of Positive_regulation of MAPK14 5 0.36 1.49 1.22
14 INT194875 Regulation of Negative_regulation of MAPK14 1 0.04 2.39 0.91
15 INT242889 Binding of SPI1 15 0.36 7.37 0.69
16 INT139840 Positive_regulation of Negative_regulation of MAPK14 2 0.21 1.55 0.67
17 INT242903 Gene_expression of SPI1 5 0.13 9.68 0.63
18 INT209936 Negative_regulation of Gene_expression of MAPK14 7 0.20 4.95 0.53
19 INT121027 Regulation of Phosphorylation of MAPK14 2 0.38 1.1 0.46
20 INT173625 Positive_regulation of Localization of MAPK14 3 0.17 1.05 0.44
21 INT179170 Protein_catabolism of MAPK14 3 0.43 0.88 0.43
22 INT255902 Positive_regulation of Binding of MAPK14 1 0.17 0.93 0.42
23 INT80141 Negative_regulation of SPI1 6 0.08 5.44 0.34
24 INT255923 Positive_regulation of Regulation of MAPK14 1 0.17 0.41 0.28
25 INT242900 Regulation of SPI1 3 0.26 1.12 0.23
26 INT267610 Negative_regulation of Negative_regulation of MAPK14 1 0.03 1.08 0.15
27 INT304667 Positive_regulation of SPI1 2 0.13 4.7 0.09
28 INT351182 Positive_regulation of Binding of SPI1 1 0.08 1.25 0.09
29 INT346252 Regulation of Gene_expression of MAPK14 1 0.38 0 0.09
30 INT242888 Negative_regulation of Binding of SPI1 1 0.10 0.41 0.06
31 INT242892 Regulation of Binding of SPI1 1 0.08 0.37 0.06
32 INT182288 Negative_regulation of Binding of MAPK14 1 0.21 0.08 0.04
33 INT182280 Negative_regulation of Localization of MAPK14 1 0.21 0.39 0.04
34 INT322953 Localization of SPI1 2 0.13 2.17 0
35 INT351181 Positive_regulation of Gene_expression of SPI1 1 0.10 1.87 0
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