GO:0051573

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Name negative regulation of histone H3-K9 methylation
Categary Process
Go Slim No
Go Link GO:0051573
Unique Molecular Interactions 49
Total Molecular Interactions 59
Total Single Events 400
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of histone H3-K9 methylation. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of histone H3-K9 methylation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT73116 TYMS Negative_regulation of DNMT3B 1 0.24 0 1.6
2 INT73115 TYMS Negative_regulation of Positive_regulation of DNMT3B 1 0.24 0 1.6
3 INT254768 DNMT1 Positive_regulation of Gene_expression of Apoe 1 0.02 0.05 0.49
4 INT150793 ZNF398 Negative_regulation of Gene_expression of DNMT1 1 0.07 0.46 0.48
5 INT353454 Binding of BRCA1 and IL17A 1 0.00 2.55 0.36
6 INT353452 Binding of AGRP and BRCA1 1 0.00 3.89 0.34
7 INT285718 Binding of DNMT3B and Lbp 1 0.08 0.33 0.33
8 INT353448 BRCA1 Positive_regulation of CCL2 1 0.01 1.37 0.26
9 INT353449 BRCA1 Positive_regulation of IL4 1 0.00 1.37 0.26
10 INT353455 BRCA1 Positive_regulation of IL13 1 0.00 1.37 0.26
11 INT228611 Binding of DNMT3B and LEP 1 0.04 0 0.25
12 INT254772 DNMT1 Positive_regulation of Apoe 1 0.02 0 0.25
13 INT254774 DNMT1 Positive_regulation of Localization of Apoe 1 0.01 0.31 0.23
14 INT254770 Regulation of Binding of DNMT1 and Igh-Dex 1 0.00 0 0.22
15 INT254771 Binding of DNMT1 and Igh-Dex 1 0.00 0 0.19
16 INT353451 Binding of BRCA1 and CRP 1 0.01 1.18 0.14
17 INT353453 Binding of BRCA1 and IL4 1 0.00 1.18 0.14
18 INT353450 Binding of BRCA1 and VEGFA 1 0.01 0.82 0.05
19 INT228610 Binding of DNMT3B and ASPRV1 1 0.02 0 0.05
20 INT347165 Binding of NOTCH1 and PAX5 1 0.05 0.86 0.03
21 INT221262 Binding of BRCA1 and CD4 1 0.22 0.81 0.03
22 INT234178 Binding of BRCA1 and BRCA2 2 0.40 1.52 0
23 INT241268 DNMT3B Positive_regulation of Gene_expression of DNMT1 1 0.19 0.67 0
24 INT234180 Binding of BRCA1 and BRIP1 1 0.33 1.37 0
25 INT314743 Binding of RAD51 and Brca1 1 0.06 1.06 0
26 INT314740 Binding of ESR1 and Brca1 1 0.16 0.69 0
27 INT284918 RUNX1T1 Regulation of DNMT1 1 0.21 1.09 0
28 INT241266 DNMT3B Positive_regulation of Gene_expression of GOPC 1 0.05 0.68 0
29 INT232595 Binding of BRCA1 and HEPACAM 1 0.02 0.89 0
30 INT183413 Dnmt3a Positive_regulation of Gene_expression of Dnmt3b 1 0.10 0.28 0
31 INT241264 DNMT1 Positive_regulation of Gene_expression of DNMT3B 1 0.19 0.67 0
32 INT241257 DNMT3B Positive_regulation of OPCML 1 0.35 0.68 0
33 INT241259 DNMT3B Positive_regulation of GOPC 1 0.05 0.68 0
34 INT183415 Dnmt3b Positive_regulation of Gene_expression of Dnmt3a 1 0.10 0.28 0
35 INT253331 Binding of DNMT3B and SP140 1 0.04 0.17 0
36 INT259091 Binding of BRCA1 and LMO4 1 0.24 0.74 0
37 INT314745 Binding of TP53 and Brca1 1 0.18 1.17 0
38 INT183410 Dnmt3b Positive_regulation of Tbx15 1 0.05 0.27 0
39 INT241265 DNMT1 Positive_regulation of OPCML 1 0.31 0.68 0
40 INT296162 Mcph1 Regulation of Brca1 1 0.26 0.19 0
41 INT241269 DNMT1 Positive_regulation of Gene_expression of GOPC 1 0.04 0.68 0
42 INT191135 Binding of DNMT3A and DNMT3B 1 0.09 0 0
43 INT241254 DNMT1 Positive_regulation of GOPC 1 0.04 0.68 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of histone H3-K9 methylation. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of histone H3-K9 methylation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT73117 Positive_regulation of DNMT3B 20 0.47 10.31 5.31
2 INT119063 Gene_expression of BRCA1 24 0.67 30.04 4.17
3 INT103350 Gene_expression of DNMT1 15 0.67 9.77 3.83
4 INT136106 Gene_expression of DNMT3B 30 0.58 8.43 3.7
5 INT121531 Negative_regulation of DNMT3B 13 0.36 3.46 3.05
6 INT133038 Binding of DNMT3B 26 0.40 5.97 2.83
7 INT221269 Binding of BRCA1 14 0.40 31.77 2.7
8 INT221422 Positive_regulation of BRCA1 5 0.23 12.63 1.53
9 INT157500 Localization of DNMT3B 12 0.73 2.21 1.38
10 INT119062 Negative_regulation of BRCA1 12 0.49 13.7 1.36
11 INT46336 Regulation of DNMT3B 12 0.53 4.91 1.25
12 INT322088 Regulation of Regulation of DNMT3B 1 0.03 2.74 1.12
13 INT285716 Negative_regulation of Gene_expression of DNMT3B 1 0.21 0.96 0.96
14 INT41590 Positive_regulation of PAX5 10 0.42 3.1 0.91
15 INT201859 Positive_regulation of Gene_expression of DNMT1 4 0.60 6.43 0.75
16 INT241287 Positive_regulation of Gene_expression of DNMT3B 3 0.40 1.21 0.57
17 INT221420 Positive_regulation of Gene_expression of BRCA1 2 0.24 2.17 0.55
18 INT146400 Positive_regulation of DNMT1 4 0.45 0.91 0.43
19 INT306690 Negative_regulation of Dnmt3b 1 0.00 0.56 0.39
20 INT353457 Positive_regulation of Binding of BRCA1 1 0.09 1.69 0.34
21 INT221419 Regulation of BRCA1 5 0.35 6.18 0.31
22 INT254763 Localization of DNMT1 1 0.05 0.2 0.29
23 INT284938 Regulation of DNMT1 2 0.22 1.17 0.24
24 INT221268 Localization of BRCA1 7 0.63 4.83 0.18
25 INT119061 Negative_regulation of Gene_expression of BRCA1 4 0.51 0.85 0.18
26 INT89689 Binding of Brca1 2 0.37 2.55 0.18
27 INT211055 Binding of PAX5 2 0.33 0.85 0.18
28 INT191163 Transcription of DNMT3B 4 0.50 0.46 0.13
29 INT210578 Gene_expression of PAX5 5 0.44 3.46 0.12
30 INT258077 Negative_regulation of Gene_expression of DNMT1 2 0.30 1.27 0.12
31 INT187590 Gene_expression of Brca1 12 0.65 4.94 0.11
32 INT258063 Negative_regulation of DNMT1 3 0.28 1.36 0.11
33 INT208914 Regulation of Brca1 1 0.10 0.79 0.11
34 INT132718 Regulation of PAX5 3 0.16 1.36 0.09
35 INT254762 Positive_regulation of Positive_regulation of DNMT1 1 0.04 0 0.09
36 INT192687 Negative_regulation of PAX5 9 0.40 1.42 0.08
37 INT174155 Negative_regulation of Brca1 4 0.36 1.77 0.07
38 INT292609 Negative_regulation of Positive_regulation of DNMT3B 1 0.22 1.3 0.07
39 INT211048 Negative_regulation of Binding of PAX5 1 0.29 0.1 0.05
40 INT211050 Positive_regulation of Binding of PAX5 1 0.34 0.1 0.05
41 INT132717 Localization of PAX5 3 0.50 1.27 0.03
42 INT187589 Positive_regulation of Gene_expression of Brca1 2 0.55 1.93 0.03
43 INT344009 Negative_regulation of Localization of BRCA1 1 0.30 0.18 0.03
44 INT284977 Binding of DNMT1 3 0.17 0.86 0
45 INT259116 Transcription of BRCA1 3 0.44 3.77 0
46 INT284945 Protein_catabolism of DNMT1 2 0.32 0.47 0
47 INT212457 Phosphorylation of Brca1 2 0.51 0.96 0
48 INT210577 Negative_regulation of Gene_expression of PAX5 1 0.11 0.49 0
49 INT187580 Positive_regulation of Brca1 1 0.10 1.17 0
50 INT191157 Negative_regulation of Transcription of DNMT3B 1 0.19 0.06 0
51 INT119064 Regulation of Gene_expression of BRCA1 1 0.53 0.05 0
52 INT314706 Transcription of Brca1 1 0.43 0.53 0
53 INT185991 Regulation of Gene_expression of DNMT3B 1 0.37 0 0
54 INT284993 Positive_regulation of Protein_catabolism of DNMT1 1 0.22 0.26 0
55 INT221271 Negative_regulation of Binding of BRCA1 1 0.28 0.93 0
56 INT334189 Regulation of Binding of BRCA1 1 0.13 0.8 0
57 INT183391 Positive_regulation of Gene_expression of Dnmt3b 1 0.20 0.59 0
58 INT234188 Positive_regulation of Localization of BRCA1 1 0.42 0.68 0
59 INT183398 Gene_expression of Dnmt3b 1 0.27 0.59 0
60 INT210576 Regulation of Gene_expression of PAX5 1 0.11 0.34 0
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