GO:0051707

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Name response to other organism
Categary Process
Go Slim No
Go Link GO:0051707
Unique Molecular Interactions 83
Total Molecular Interactions 125
Total Single Events 1141
Pain Genes Associated 8

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for response to other organism. They are ordered first by their pain relevance and then by number of times they were reported for response to other organism. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT102284 Binding of Grin1 and Grin2a 5 0.27 1.79 3.01
2 INT249498 Src Positive_regulation of Phosphorylation of Grin2b 1 0.22 1.11 1.54
3 INT293200 Positive_regulation of Grin1 Positive_regulation of Phosphorylation of Grin2b 1 0.24 0.4 1.39
4 INT98908 Binding of NTRK1 and PKLR 1 0.41 1.95 1.18
5 INT98906 Positive_regulation of Binding of NTRK1 and PKLR 1 0.56 1.95 1.18
6 INT122267 Prkcg Positive_regulation of Grin2b 1 0.26 0.61 1.14
7 INT132683 Bdnf Positive_regulation of Phosphorylation of Grin2a 1 0.00 0.93 1.11
8 INT122268 Binding of Grin2b and Grm5 1 0.40 0.52 1.1
9 INT269189 Binding of Grin2a and Grin3a 2 0.25 1.05 1.09
10 INT269193 Prkcg Regulation of Phosphorylation of Grin2a 1 0.02 0.63 1.06
11 INT269192 Ephb1 Regulation of Phosphorylation of Grin2a 1 0.02 0.63 1.06
12 INT269198 Prkaca Regulation of Phosphorylation of Grin2a 1 0.02 0.63 1.06
13 INT353690 Binding of Grin2b and Ca2 1 0.14 1.17 1.01
14 INT122269 Src Negative_regulation of Positive_regulation of Grin2b 1 0.27 0.44 0.92
15 INT199392 Pklr Positive_regulation of Prok2 1 0.34 1.3 0.91
16 INT122266 Src Negative_regulation of Grin2b 1 0.27 0.43 0.91
17 INT199391 Pklr Positive_regulation of Prokr1 1 0.31 1.28 0.87
18 INT166634 Binding of Bcl2 and Becn1 1 0.20 0.5 0.86
19 INT212290 Binding of Grin2a and Grin2b 2 0.20 1.36 0.82
20 INT186160 Negative_regulation of Grin2b Negative_regulation of Grin1 1 0.37 0.5 0.72
21 INT249485 Trib3 Negative_regulation of Phosphorylation of Grin2b 1 0.02 0.64 0.68
22 INT199390 Pklr Regulation of Positive_regulation of Prokr1 1 0.18 0.89 0.68
23 INT250084 Negative_regulation of Grin2b Negative_regulation of Positive_regulation of Ltp 1 0.18 0.07 0.66
24 INT249489 Src Negative_regulation of Phosphorylation of Grin2b 1 0.20 0.63 0.66
25 INT250078 Negative_regulation of Grin2b Negative_regulation of Ltp 1 0.18 0.07 0.66
26 INT302441 Binding of GRIN1 and Grin2b 1 0.10 1.27 0.63
27 INT186159 Grin2d Negative_regulation of Grin2b 1 0.21 0.82 0.62
28 INT249484 Trib3 Positive_regulation of Phosphorylation of Grin2b 1 0.01 0.57 0.61
29 INT134532 Grin2a Regulation of Ngfr 1 0.02 0 0.57
30 INT249497 Efnb2 Positive_regulation of Phosphorylation of Grin2b 1 0.02 0.51 0.54
31 INT249479 Binding of Ephb1 and Grin2b 1 0.29 0.37 0.54
32 INT250080 Grin2b Positive_regulation of Ltp 1 0.22 0.19 0.49
33 INT250081 Grin2a Positive_regulation of Ltp 1 0.20 0.14 0.48
34 INT249486 Positive_regulation of Ephb1 Positive_regulation of Phosphorylation of Grin2b 1 0.33 0.4 0.46
35 INT127394 Negative_regulation of Ephb1 Negative_regulation of Gene_expression of Grin2a 1 0.01 0.71 0.45
36 INT127396 Negative_regulation of Mdk Negative_regulation of Gene_expression of Grin2a 1 0.00 0.71 0.45
37 INT105733 Grin2b Negative_regulation of Gene_expression of Grin2a 1 0.22 0.09 0.41
38 INT279620 Negative_regulation of Binding of Grin2a and Grin2b 1 0.18 0.99 0.4
39 INT233513 Pklr Negative_regulation of Localization of Il10 1 0.04 1.12 0.39
40 INT250076 Grin2a Regulation of Positive_regulation of Ltp 1 0.10 0.06 0.35
41 INT249492 Trib3 Regulation of Phosphorylation of Grin2b 1 0.01 0.23 0.35
42 INT236006 HTR1A Regulation of Grin2b 1 0.00 0 0.33
43 INT165580 Binding of Akt1 and Grin2b 1 0.02 0.2 0.32
44 INT250079 Grin2b Regulation of Ltp 1 0.18 0.31 0.29
45 INT212289 Vsnl1 Negative_regulation of Grin2a 1 0.04 0.38 0.28
46 INT233515 Pklr Positive_regulation of Gene_expression of Tnf 1 0.05 1.12 0.27
47 INT249493 Binding of Grin2b and Src 1 0.17 0.15 0.26
48 INT250075 Binding of Hpcal4 and Negative_regulation of Gene_expression of Grin2a 1 0.03 0 0.24
49 INT250074 Grin2b Positive_regulation of Gene_expression of Hpcal4 1 0.04 0.3 0.2
50 INT249495 Binding of Grin2b and Efnb2 1 0.02 0.05 0.11
51 INT190246 TARBP2 Positive_regulation of PKLR 1 0.01 0.41 0.1
52 INT233521 Binding of Pklr and Prokr1 1 0.17 0.44 0.07
53 INT145622 Binding of PKLR and UGT1A3 1 0.01 0 0.06
54 INT145623 Binding of PKLR and UGT2B4 1 0.02 0 0.06
55 INT145626 Binding of PKLR and UGT1A1 1 0.02 0 0.06
56 INT145621 Binding of PKLR and UGT2B7 1 0.02 0 0.06
57 INT145624 Binding of PKLR and UGT1A9 1 0.02 0 0.06
58 INT145625 Binding of PKLR and UGT2B17 1 0.01 0 0.06
59 INT331227 Binding of Becn1 and Pink1 1 0.03 1.13 0.05
60 INT250073 Grin2a Regulation of Grin2b 1 0.39 0.9 0.05
61 INT190247 TARBP2 Negative_regulation of PKLR 1 0.01 0.2 0.05
62 INT232900 Binding of ABR and Krt8 1 0.03 0.49 0.03
63 INT282995 Binding of Bcl2 and Becn1 21 0.03 9.8 0
64 INT283001 Binding of Becn1 and Om 1 0.00 0.1 0
65 INT331226 Binding of Becn1 and Pik3c3 1 0.02 0.47 0
66 INT313271 Binding of GRIN1 and GRIN2B 1 0.24 0.06 0
67 INT169858 Grin1 Regulation of Gene_expression of Grin2b 1 0.42 0 0
68 INT283000 Negative_regulation of Binding of Bcl2 and Becn1 1 0.03 0.71 0
69 INT331230 Binding of Mapk8 and Becn1 1 0.02 0.77 0
70 INT283010 Regulation of Binding of Bcl2 and Becn1 1 0.03 1.45 0
71 INT232898 Binding of KRT1 and Krt8 1 0.27 1.22 0
72 INT283004 Binding of Becn1 and Pdss2 1 0.00 0.57 0
73 INT232896 Krt8 Negative_regulation of Binding of ABR 1 0.04 0.68 0
74 INT283008 Igkv1-131 Regulation of Binding of Becn1 1 0.01 0 0
75 INT232892 Krt18 Positive_regulation of Gene_expression of Krt8 1 0.30 0.09 0
76 INT283014 Becn1 Regulation of Bcl2 1 0.03 0.88 0
77 INT232889 Binding of Krt18 and Krt8 1 0.22 1.09 0
78 INT169856 Grin1 Positive_regulation of Grin2b 1 0.46 0 0
79 INT301639 Positive_regulation of Mlxipl Positive_regulation of Gene_expression of Pklr 1 0.03 0.52 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for response to other organism. They are ordered first by their pain relevance and then by number of times they were reported in response to other organism. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT104000 Phosphorylation of Grin2b 73 0.82 48.34 93.48
2 INT79506 Gene_expression of Grin2b 122 0.78 43.71 73.42
3 INT51627 Gene_expression of Grin2a 82 0.76 25.09 47.6
4 INT82054 Positive_regulation of Grin2b 56 0.70 17.45 37.14
5 INT103998 Positive_regulation of Phosphorylation of Grin2b 33 0.69 19.08 36.08
6 INT93033 Negative_regulation of Grin2b 48 0.58 20.94 28.54
7 INT102281 Positive_regulation of Gene_expression of Grin2b 27 0.70 10.38 20.84
8 INT90612 Positive_regulation of Grin2a 33 0.65 15.11 18.84
9 INT93037 Regulation of Grin2b 26 0.57 11.9 16.92
10 INT103996 Negative_regulation of Phosphorylation of Grin2b 11 0.58 7.81 12.85
11 INT103997 Phosphorylation of Grin2a 17 0.64 10.75 12.67
12 INT122117 Negative_regulation of Gene_expression of Grin2b 20 0.59 11.3 12.55
13 INT51625 Regulation of Gene_expression of Grin2a 12 0.60 3.28 11.6
14 INT51626 Transcription of Grin2a 16 0.68 1.65 10.5
15 INT93036 Negative_regulation of Grin2a 23 0.50 7.1 10.32
16 INT80006 Regulation of Gene_expression of Grin2b 8 0.57 3.75 9.62
17 INT95342 Gene_expression of GRIN2B 21 0.75 4.99 9.32
18 INT78769 Regulation of Grin2a 16 0.58 5.22 9.28
19 INT100926 Positive_regulation of Gene_expression of Grin2a 11 0.63 3.24 6.41
20 INT100658 Negative_regulation of Positive_regulation of Grin2b 7 0.41 1.39 6.17
21 INT74593 Transcription of Grin2b 10 0.66 1.21 5.98
22 INT67693 Binding of Grin2a 9 0.38 1.74 5.68
23 INT127353 Regulation of Phosphorylation of Grin2b 5 0.45 1.6 5.29
24 INT92541 Localization of Grin2b 11 0.75 2.85 5.14
25 INT79505 Binding of Grin2b 9 0.36 1.43 4.61
26 INT103999 Positive_regulation of Phosphorylation of Grin2a 5 0.38 3.12 3.94
27 INT90611 Positive_regulation of Positive_regulation of Grin2a 4 0.63 1.89 3
28 INT105730 Localization of Grin2a 7 0.67 0.64 2.56
29 INT101055 Regulation of GRIN2B 4 0.61 1.39 2.5
30 INT151942 Regulation of Negative_regulation of Grin2b 2 0.41 0.41 1.92
31 INT74595 Regulation of Transcription of Grin2a 2 0.42 0.66 1.92
32 INT103624 Negative_regulation of Gene_expression of Grin2a 5 0.56 1.58 1.9
33 INT151174 Negative_regulation of Transcription of Grin2a 3 0.40 0 1.8
34 INT74594 Regulation of Transcription of Grin2b 1 0.42 0.17 1.8
35 INT130440 Phosphorylation of GRIN2B 2 0.79 2.93 1.79
36 INT107379 Localization of GRIN2B 2 0.73 0.86 1.48
37 INT105729 Negative_regulation of Localization of Grin2a 3 0.38 0.08 1.29
38 INT166628 Positive_regulation of Gene_expression of Becn1 2 0.67 1.03 1.23
39 INT166632 Gene_expression of Becn1 2 0.75 1.02 1.22
40 INT249527 Positive_regulation of Positive_regulation of Grin2b 2 0.37 1.12 1.22
41 INT95347 Negative_regulation of GRIN2B 1 0.57 0 1.19
42 INT199308 Gene_expression of Krt8 37 0.75 23.17 1.06
43 INT60286 Gene_expression of PKLR 5 0.65 2.14 1.04
44 INT120408 Localization of PKLR 1 0.01 0.8 0.99
45 INT101056 Positive_regulation of GRIN2B 1 0.23 0.32 0.9
46 INT166630 Negative_regulation of Localization of Becn1 1 0.41 0.51 0.88
47 INT166626 Localization of Becn1 1 0.76 0.5 0.87
48 INT171406 Gene_expression of Pklr 3 0.65 2.75 0.86
49 INT166633 Binding of Becn1 1 0.45 0.5 0.86
50 INT166629 Negative_regulation of Binding of Becn1 1 0.41 0.5 0.86
51 INT186168 Negative_regulation of Negative_regulation of Grin2b 2 0.35 0.54 0.85
52 INT166631 Positive_regulation of Becn1 1 0.41 0.52 0.84
53 INT92862 Positive_regulation of Pklr 1 0.02 0.06 0.83
54 INT165578 Regulation of Positive_regulation of Grin2b 3 0.41 1.07 0.74
55 INT114524 Binding of GRIN2B 3 0.36 0.44 0.74
56 INT157073 Positive_regulation of PKLR 6 0.36 5.48 0.69
57 INT139895 Positive_regulation of Gene_expression of GRIN2B 2 0.49 0.9 0.65
58 INT122116 Negative_regulation of Transcription of Grin2b 1 0.43 0.34 0.62
59 INT271625 Protein_catabolism of Grin2b 1 0.38 0.26 0.57
60 INT60289 Negative_regulation of PKLR 5 0.21 1.75 0.53
61 INT120399 Positive_regulation of Phosphorylation of PKLR 1 0.01 0.44 0.53
62 INT156379 Regulation of Binding of Grin2a 1 0.36 0.17 0.52
63 INT156378 Regulation of Binding of Grin2b 1 0.28 0.17 0.52
64 INT120389 Phosphorylation of PKLR 2 0.11 1.81 0.51
65 INT163895 Positive_regulation of Phosphorylation of GRIN2B 1 0.09 0.99 0.48
66 INT271628 Negative_regulation of Regulation of Grin2a 2 0.28 1.05 0.47
67 INT271632 Negative_regulation of Regulation of Grin2b 2 0.28 1.06 0.47
68 INT250065 Positive_regulation of Localization of Grin2b 1 0.45 0 0.47
69 INT250060 Positive_regulation of Localization of Grin2a 1 0.42 0 0.47
70 INT232840 Positive_regulation of Gene_expression of Krt8 1 0.44 4.51 0.42
71 INT232825 Positive_regulation of Krt8 1 0.44 6.83 0.42
72 INT271627 Regulation of Positive_regulation of Grin2a 1 0.30 0.23 0.4
73 INT111822 Binding of Krt8 6 0.34 4.61 0.39
74 INT271630 Negative_regulation of Localization of Grin2b 1 0.25 0 0.37
75 INT60287 Regulation of PKLR 1 0.15 0.32 0.35
76 INT250062 Positive_regulation of Transcription of Grin2b 1 0.39 0.47 0.34
77 INT249529 Regulation of Phosphorylation of Grin2a 1 0.21 0.16 0.34
78 INT140349 Positive_regulation of Localization of Pklr 1 0.01 0.38 0.33
79 INT140352 Localization of Pklr 1 0.02 0.38 0.33
80 INT237038 Gene_expression of Becn1 18 0.36 13.68 0.31
81 INT345368 Negative_regulation of Krt8 1 0.00 7.25 0.31
82 INT60288 Regulation of Gene_expression of PKLR 1 0.15 0.32 0.28
83 INT163897 Negative_regulation of Phosphorylation of GRIN2B 1 0.08 0.39 0.28
84 INT271629 Positive_regulation of Protein_catabolism of Grin2b 1 0.27 0.13 0.28
85 INT212295 Regulation of Negative_regulation of Grin2a 1 0.39 0.28 0.24
86 INT108279 Positive_regulation of Binding of Grin2a 1 0.41 0 0.23
87 INT125877 Binding of PKLR 2 0.04 0.26 0.22
88 INT232824 Regulation of Krt8 1 0.29 1.64 0.21
89 INT232822 Negative_regulation of Gene_expression of Krt8 5 0.36 2.3 0.08
90 INT282981 Positive_regulation of Gene_expression of Becn1 8 0.13 6.2 0.06
91 INT232850 Phosphorylation of Krt8 7 0.52 3.8 0.05
92 INT282985 Negative_regulation of Becn1 11 0.20 7.72 0.04
93 INT282977 Regulation of Becn1 4 0.25 2.29 0.04
94 INT282974 Binding of Becn1 24 0.07 7.43 0
95 INT282990 Negative_regulation of Binding of Becn1 6 0.08 1.44 0
96 INT282967 Negative_regulation of Gene_expression of Becn1 3 0.08 2.04 0
97 INT331187 Positive_regulation of Becn1 2 0.09 1.01 0
98 INT82996 Transcription of PKLR 2 0.51 0.6 0
99 INT282988 Regulation of Binding of Becn1 2 0.05 0 0
100 INT282978 Positive_regulation of Binding of Becn1 1 0.04 0 0
101 INT232832 Localization of Krt8 1 0.48 0.84 0
102 INT232847 Negative_regulation of Protein_catabolism of Krt8 1 0.33 0.13 0
103 INT330341 Positive_regulation of Gene_expression of PKLR 1 0.08 1.13 0
104 INT232820 Protein_catabolism of Krt8 1 0.55 0.13 0
105 INT232849 Negative_regulation of Phosphorylation of Krt8 1 0.27 0.24 0
106 INT232836 Regulation of Gene_expression of Krt8 1 0.29 1.57 0
107 INT325712 Regulation of Gene_expression of Becn1 1 0.03 0.35 0
108 INT319097 Negative_regulation of Transcription of PKLR 1 0.05 0.24 0
109 INT301550 Positive_regulation of Gene_expression of Pklr 1 0.13 0.51 0
110 INT319098 Protein_catabolism of PKLR 1 0.13 0.49 0
111 INT232846 Regulation of Positive_regulation of Krt8 1 0.29 0.71 0
112 INT282969 Protein_catabolism of Becn1 1 0.08 0 0
113 INT232851 Positive_regulation of Phosphorylation of Krt8 1 0.32 0.47 0
114 INT330349 Negative_regulation of Gene_expression of PKLR 1 0.07 1.23 0
115 INT155518 Negative_regulation of Phosphorylation of Grin2a 1 0.31 0.05 0
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