GO:0051764

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Name actin crosslink formation
Categary Process
Go Slim No
Go Link GO:0051764
Unique Molecular Interactions 34
Total Molecular Interactions 75
Total Single Events 469
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for actin crosslink formation. They are ordered first by their pain relevance and then by number of times they were reported for actin crosslink formation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT259233 Binding of Oprm1 and Flna 1 0.03 0.25 25.89
2 INT221180 Binding of OPRM1 and Flna 1 0.09 0.22 12.65
3 INT259209 Binding of Glul and Flna 1 0.03 0 4.2
4 INT259230 Negative_regulation of Binding of Oprm1 and Flna 1 0.02 0 4.15
5 INT221181 Binding of GOPC and Flna 1 0.03 0.06 2.08
6 INT221182 Negative_regulation of Binding of OPRM1 and Flna 1 0.07 0 1.57
7 INT259232 Binding of Flna and Positive_regulation of Localization of Oprm1 1 0.03 0 1.39
8 INT259211 Binding of Ppp1r9b and Flna 1 0.06 0 1.33
9 INT259229 Positive_regulation of Binding of Oprm1 and Flna 1 0.02 0 1.23
10 INT113946 Binding of FLNA and OPRM1 1 0.10 0.37 0.9
11 INT333991 Binding of FLNA and SELL 1 0.00 1.69 0.55
12 INT222691 Negative_regulation of Binding of FLNA and TNF 1 0.14 1.92 0.54
13 INT222692 Binding of FLNA and TNF 1 0.12 1.92 0.53
14 INT113950 FLNA Regulation of Oprd1 1 0.00 0.16 0.32
15 INT191619 Binding of App and Flna 1 0.04 0.18 0.24
16 INT130740 Regulation of Binding of Tnnt2 and Mb 1 0.00 0.47 0.19
17 INT130741 Binding of Tnnt2 and Mb 1 0.01 0.47 0.19
18 INT191609 Binding of Drd3 and Flna 1 0.06 0.42 0.17
19 INT191615 Binding of Nf1 and Flna 1 0.08 0.53 0.17
20 INT168856 Binding of Tnnt2 and Fabp3 1 0.05 0.57 0.09
21 INT236531 Binding of Cacna1f and Flna 1 0.08 0 0.07
22 INT250015 Binding of FLNA and Nos3 1 0.05 1.09 0.06
23 INT305383 Binding of NKX2-5 and FLNA 1 0.10 0.7 0.04
24 INT241450 Binding of Rhoa and Dpysl3 1 0.02 0 0.03
25 INT213585 Binding of CFTR and FLNA 1 0.14 0.11 0.03
26 INT338018 Binding of AR and Flna 1 0.11 0.33 0
27 INT255164 Regulation of PM20D2 Regulation of FLNA 1 0.00 0.82 0
28 INT236528 Binding of Cav1 and Flna 1 0.06 0.09 0
29 INT322249 Binding of Hcm and Tnnt2 1 0.11 0.86 0
30 INT255165 PM20D2 Regulation of FLNA 1 0.00 0.76 0
31 INT338021 Binding of Flna and Regulation of Transcription of AR 1 0.14 0.33 0
32 INT255163 Binding of FLNA and PM20D2 1 0.00 0 0
33 INT236529 Binding of Om and Flna 1 0.00 0.09 0
34 INT277310 Binding of Tnnt2 and Mbnl1 1 0.18 1.1 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for actin crosslink formation. They are ordered first by their pain relevance and then by number of times they were reported in actin crosslink formation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT221172 Binding of Flna 32 0.42 1.37 51.59
2 INT221167 Gene_expression of Flna 11 0.60 0.69 11.81
3 INT68373 Negative_regulation of FLNA 59 0.57 60.46 9.55
4 INT221173 Negative_regulation of Binding of Flna 4 0.33 0.13 8.25
5 INT63957 Positive_regulation of Tnnt2 33 0.69 18.56 5.41
6 INT113948 Gene_expression of FLNA 32 0.73 36.06 4.81
7 INT39948 Binding of FLNA 45 0.42 58.05 4.27
8 INT221168 Localization of Flna 1 0.58 0.05 4.05
9 INT63880 Positive_regulation of FLNA 29 0.59 13.88 3.97
10 INT221171 Positive_regulation of Localization of Flna 1 0.39 0.05 2.9
11 INT99550 Regulation of FLNA 51 0.54 27.88 2.58
12 INT46646 Localization of FLNA 19 0.73 18.83 2.53
13 INT259224 Negative_regulation of Flna 1 0.23 0.15 2.51
14 INT168097 Transcription of Tnnt2 1 0.07 2.12 2.47
15 INT81247 Gene_expression of Tnnt2 9 0.31 2.06 2.37
16 INT221177 Negative_regulation of Gene_expression of Flna 2 0.33 0 2.22
17 INT118896 Regulation of Tnnt2 4 0.44 2.94 2.09
18 INT221179 Regulation of Flna 1 0.24 0.13 2.04
19 INT221166 Positive_regulation of Flna 2 0.39 0.09 1.7
20 INT259219 Negative_regulation of Negative_regulation of Flna 1 0.23 0 1.47
21 INT72458 Positive_regulation of Tnnt2 5 0.69 5.59 1.38
22 INT47434 Gene_expression of Tnnt2 14 0.60 10.4 1.37
23 INT96117 Negative_regulation of Tnnt2 3 0.13 1.61 1.1
24 INT142423 Negative_regulation of Positive_regulation of FLNA 2 0.05 0.99 0.89
25 INT63958 Regulation of Tnnt2 7 0.45 5.36 0.7
26 INT64536 Binding of Tnnt2 4 0.32 2.47 0.64
27 INT113949 Positive_regulation of Gene_expression of FLNA 2 0.44 0.34 0.39
28 INT221178 Positive_regulation of Gene_expression of Flna 1 0.39 0 0.38
29 INT64537 Localization of Tnnt2 5 0.76 1.57 0.37
30 INT214618 Transcription of FLNA 4 0.51 8.06 0.37
31 INT73898 Positive_regulation of Regulation of Tnnt2 1 0.44 0.83 0.37
32 INT134059 Negative_regulation of Negative_regulation of FLNA 1 0.02 0.38 0.18
33 INT287862 Phosphorylation of Tnnt2 1 0.42 0.07 0.12
34 INT304610 Positive_regulation of Localization of FLNA 1 0.09 0.98 0.12
35 INT311275 Regulation of Gene_expression of Tnnt2 2 0.34 1.33 0.1
36 INT121284 Positive_regulation of Gene_expression of Tnnt2 2 0.46 0.89 0.1
37 INT121285 Regulation of Positive_regulation of Tnnt2 2 0.45 0.84 0.09
38 INT168853 Binding of Tnnt2 2 0.19 0.4 0.08
39 INT305385 Negative_regulation of Localization of FLNA 1 0.16 0.79 0.08
40 INT178278 Regulation of Positive_regulation of FLNA 1 0.04 0.4 0.05
41 INT104302 Localization of Tnnt2 2 0.70 0.52 0.04
42 INT183436 Positive_regulation of Localization of Tnnt2 1 0.30 0.45 0.04
43 INT236523 Binding of Flna 3 0.30 0.45 0.03
44 INT276544 Gene_expression of Flna 3 0.63 1.97 0
45 INT276523 Negative_regulation of Gene_expression of Flna 2 0.48 0.8 0
46 INT255134 Positive_regulation of Localization of Tnnt2 1 0.44 0.15 0
47 INT287846 Positive_regulation of Phosphorylation of Tnnt2 1 0.25 0 0
48 INT255171 Negative_regulation of Binding of FLNA 1 0.14 0.39 0
49 INT255106 Positive_regulation of Binding of Tnnt2 1 0.44 0.17 0
50 INT214620 Regulation of Localization of FLNA 1 0.02 0.46 0
51 INT214621 Regulation of Gene_expression of FLNA 1 0.02 1.09 0
52 INT337958 Localization of Flna 1 0.61 0.43 0
53 INT241408 Binding of Dpysl3 1 0.05 0 0
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