GO:0051770

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Name positive regulation of nitric-oxide synthase biosynthetic process
Categary Process
Go Slim No
Go Link GO:0051770
Unique Molecular Interactions 1040
Total Molecular Interactions 1644
Total Single Events 9819
Pain Genes Associated 27

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of nitric-oxide synthase biosynthetic process. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of nitric-oxide synthase biosynthetic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT179502 Binding of Cd14 and Tlr4 29 0.39 13.77 5.73
2 INT95068 Tlr4 Positive_regulation of IL1B 1 0.03 4.54 5.6
3 INT182124 Binding of IRF6 and TLR4 14 0.10 16.11 4.65
4 INT149492 PNOC Negative_regulation of Gene_expression of CCL2 1 0.15 0.68 3.17
5 INT61733 Tlr4 Positive_regulation of Gene_expression of Tnf 3 0.26 1.99 2.36
6 INT124121 IL6 Positive_regulation of CCL2 1 0.26 1.84 2.25
7 INT124120 IL6 Regulation of CCL2 1 0.15 1.8 2.22
8 INT128997 Cxcl1 Positive_regulation of Localization of Ccl2 1 0.72 1.54 2.16
9 INT128996 Ccl2 Positive_regulation of Localization of Calca 1 0.68 1.43 2
10 INT137917 Oprm1 Positive_regulation of Kdr 1 0.43 0 1.98
11 INT264953 Binding of POMC and TLR4 1 0.03 0.89 1.96
12 INT157767 Binding of TLR4 and LY96 8 0.54 4.05 1.95
13 INT264947 Binding of POMC and TLR2 1 0.03 0.89 1.95
14 INT161224 Ccl2 Positive_regulation of Ccr2 1 0.52 2.09 1.88
15 INT215100 Binding of Hmgb1 and Tlr4 5 0.29 3.21 1.68
16 INT215096 Binding of Hmgb1 and Tlr2 9 0.38 11.61 1.61
17 INT79778 Tlr4 Positive_regulation of Localization of TNF 4 0.08 4.21 1.61
18 INT113337 EPO Positive_regulation of JAK2 1 0.76 2.8 1.55
19 INT254205 Binding of Myd88 and Tlr4 12 0.19 3.17 1.54
20 INT294775 IRF6 Positive_regulation of TLR4 6 0.08 2.04 1.32
21 INT181436 Binding of Ccl2 and Eae1 1 0.05 5.14 1.27
22 INT78066 Tlr4 Positive_regulation of Localization of Il6 5 0.03 0.76 1.25
23 INT254210 Binding of Cxcr2 and Ccl2 1 0.08 2.39 1.25
24 INT161507 Tlr4 Positive_regulation of Gene_expression of Il1b 1 0.24 0.19 1.25
25 INT161508 Tlr4 Positive_regulation of Mapk14 2 0.19 0.46 1.24
26 INT151648 TLR4 Regulation of Gene_expression of ICAM1 1 0.00 2.86 1.24
27 INT200455 OPRK1 Positive_regulation of Gene_expression of CCL2 1 0.19 0.07 1.21
28 INT161509 Tlr4 Positive_regulation of Mapk8 1 0.15 0.3 1.16
29 INT161510 Tlr4 Positive_regulation of Mapk1 1 0.14 0.3 1.16
30 INT185321 Tlr4 Positive_regulation of Gene_expression of Il6 5 0.14 1.97 1.15
31 INT89938 Tlr4 Positive_regulation of Gene_expression of TNF 6 0.25 1.3 1.12
32 INT260810 Binding of CXCL10 and CCL2 1 0.10 1.37 1.12
33 INT173059 Binding of KDR and VEGFA 43 0.43 29.63 1.1
34 INT167426 Tlr4 Positive_regulation of Localization of Gpt 1 0.25 1.26 1.1
35 INT130656 Tlr4 Positive_regulation of Cyba 1 0.00 0.05 1.09
36 INT130657 Negative_regulation of Tlr4 Positive_regulation of Cyba 1 0.00 0.05 1.09
37 INT185373 IRF6 Positive_regulation of Gene_expression of TLR2 1 0.08 2.96 1.04
38 INT181434 Binding of Ccr2 and Ccl2 1 0.27 6.06 1.04
39 INT182125 Binding of CD14 and TLR4 7 0.25 3.78 1.03
40 INT167173 Binding of Ccl2 and Ccr2 2 0.30 1.15 0.98
41 INT137920 Binding of Kdr and Oprm1 1 0.23 0 0.97
42 INT135585 CSF2 Regulation of CCL2 1 0.13 2.51 0.95
43 INT145163 Tlr4 Positive_regulation of Localization of Nsfl1c 1 0.02 0.43 0.94
44 INT219154 Binding of HMGB1 and TLR4 2 0.17 4.45 0.93
45 INT336017 Vip Regulation of Tlr4 1 0.22 1.23 0.93
46 INT129003 Ccl2 Positive_regulation of ANTXRL 1 0.00 0.68 0.92
47 INT306327 Binding of Ly96 and Tlr4 1 0.10 1.83 0.91
48 INT343909 IgG Positive_regulation of Gene_expression of TLR4 1 0.04 3.49 0.91
49 INT221386 Tlr4 Positive_regulation of Gene_expression of IL8 6 0.14 3.53 0.9
50 INT276964 Binding of Tlr1 and Tlr2 11 0.24 4.22 0.89
51 INT120147 Tlr4 Positive_regulation of Tnf 3 0.39 2.14 0.89
52 INT168281 Tlr4 Positive_regulation of Phosphorylation of Mapk4 1 0.06 1.05 0.89
53 INT244323 Csf2 Positive_regulation of Gene_expression of Tlr4 1 0.23 1.93 0.85
54 INT196578 Ephb1 Positive_regulation of Phosphorylation of Mapk9 1 0.13 0.5 0.85
55 INT196576 Trib3 Positive_regulation of Phosphorylation of Mapk9 1 0.02 0.5 0.85
56 INT260842 Binding of NRP2 and Kdr 1 0.00 2.28 0.85
57 INT146919 Tnf Positive_regulation of Gene_expression of Ccl2 1 0.16 1.44 0.84
58 INT302379 Crp Positive_regulation of Gene_expression of Ccl2 1 0.10 4.58 0.84
59 INT184114 Tlr4 Positive_regulation of Socs3 2 0.65 1.14 0.83
60 INT287494 CRP Positive_regulation of Gene_expression of CCL2 2 0.30 2.33 0.83
61 INT149561 Tgfb1 Positive_regulation of Gene_expression of CCL2 1 0.00 0 0.83
62 INT149563 Tgfb1 Positive_regulation of CCL2 1 0.00 0 0.83
63 INT152236 Tlr4 Regulation of Gene_expression of Nos2 3 0.19 0.64 0.82
64 INT87489 CALCA Positive_regulation of Gene_expression of CCL2 1 0.43 0.14 0.81
65 INT276988 Binding of Tlr6 and Tlr2 11 0.26 4.89 0.79
66 INT239671 Binding of Ccl2 and Gtf3a 1 0.02 1.34 0.79
67 INT223753 Tlr4 Positive_regulation of Gene_expression of Il10 4 0.32 1.93 0.78
68 INT296787 Tbrs1 Positive_regulation of Gene_expression of Tlr9 1 0.06 1.37 0.78
69 INT152235 Mapk8 Positive_regulation of Localization of Tlr4 1 0.38 0.26 0.78
70 INT149495 PNOC Negative_regulation of CCL2 1 0.11 0.16 0.77
71 INT296797 Tlr9 Regulation of Positive_regulation of TNF 1 0.03 1.37 0.77
72 INT339495 Tlr4 Positive_regulation of Eif2ak2 1 0.21 0.58 0.77
73 INT134049 Jak2 Positive_regulation of Gsk3b 1 0.37 0.22 0.77
74 INT296788 Tlr9 Regulation of Positive_regulation of Il1 1 0.07 1.37 0.77
75 INT194644 Tlr4 Positive_regulation of TNF 6 0.58 2.42 0.76
76 INT134043 Jak2 Positive_regulation of Akt1 1 0.31 0.22 0.76
77 INT134051 Jak2 Positive_regulation of Stat3 1 0.44 0.22 0.76
78 INT296792 Tlr9 Regulation of Gene_expression of Il6 1 0.06 1.36 0.76
79 INT258644 Binding of CCL2 and CCL5 1 0.36 1.6 0.74
80 INT258643 Positive_regulation of Binding of CCL2 and CCL5 1 0.49 1.61 0.74
81 INT284306 Tlr4 Positive_regulation of Adrb3 1 0.00 1.19 0.74
82 INT331599 Tlr9 Positive_regulation of Gene_expression of Il6 1 0.03 1.8 0.73
83 INT222432 Binding of Tlr4 and Cd14 1 0.02 0.74 0.71
84 INT89936 Tlr4 Positive_regulation of Il6 3 0.49 0.95 0.7
85 INT120017 CCL2 Positive_regulation of CCL3 1 0.01 0.99 0.7
86 INT120020 VEGFA Positive_regulation of CCL2 1 0.00 1 0.7
87 INT120035 CCL2 Positive_regulation of Prap1 1 0.00 0.99 0.7
88 INT215098 Tlr4 Positive_regulation of Localization of Il6 3 0.18 1.18 0.69
89 INT280951 Tlr4 Positive_regulation of Localization of S100a8 1 0.01 1.09 0.69
90 INT130717 Binding of OPRM1 and Positive_regulation of Localization of CCL2 1 0.00 0.72 0.68
91 INT215093 Tlr4 Positive_regulation of Localization of Hmgb1 1 0.32 2.9 0.68
92 INT306020 Binding of LBP and Tlr4 1 0.13 0.34 0.66
93 INT120144 Negative_regulation of Tlr4 Positive_regulation of Tnf 1 0.18 0.91 0.66
94 INT343851 Positive_regulation of Binding of IRF6 and TLR4 1 0.07 1.96 0.66
95 INT116441 IL1B Positive_regulation of Gene_expression of CCL2 2 0.04 0.62 0.65
96 INT153750 Binding of CCL2 and Crp 1 0.02 1.8 0.65
97 INT296790 Tlr9 Regulation of Bax 1 0.14 0.76 0.65
98 INT296785 Tlr9 Regulation of Bcl2 1 0.19 0.76 0.65
99 INT153751 Regulation of Binding of CCL2 and Crp 1 0.03 1.8 0.65
100 INT244320 Tlr4 Positive_regulation of Aliq1 3 0.04 4.51 0.64
101 INT281130 Ccl2 Regulation of Gene_expression of Ccr2 1 0.04 1.09 0.64
102 INT264329 Binding of IL-17 and Positive_regulation of Localization of Ccl2 1 0.13 1.65 0.64
103 INT281134 Ccl2 Positive_regulation of Gene_expression of Ccr2 1 0.08 1.09 0.64
104 INT281122 Ccl2 Regulation of Ccr2 1 0.04 1.09 0.63
105 INT174860 VEGFA Positive_regulation of Localization of CCL2 1 0.21 1.68 0.63
106 INT252772 ELANE Regulation of Gene_expression of CCL2 1 0.05 2.16 0.62
107 INT252826 ROS1 Regulation of Gene_expression of CCL2 1 0.20 2.17 0.62
108 INT339393 Tlr4 Positive_regulation of Nfkb1 1 0.24 2.06 0.61
109 INT237907 Tlr4 Positive_regulation of Gene_expression of Tlr2 7 0.40 5.85 0.6
110 INT242883 INS Negative_regulation of Gene_expression of TLR2 1 0.17 2.35 0.6
111 INT276603 Il10 Positive_regulation of Gene_expression of Tlr4 1 0.12 0.49 0.6
112 INT140264 Tlr4 Positive_regulation of Nfkb1 1 0.00 0.23 0.59
113 INT140263 Negative_regulation of Tlr4 Positive_regulation of Nfkb1 1 0.00 0.23 0.59
114 INT275552 Tlr4 Positive_regulation of Gene_expression of Il1 1 0.00 1.28 0.59
115 INT176470 TNF Positive_regulation of Gene_expression of CCL2 1 0.15 0.62 0.58
116 INT212813 Tlr4 Positive_regulation of Nos2 3 0.34 0.89 0.57
117 INT162789 Binding of TLR2 and NOD2 1 0.37 0.51 0.57
118 INT162790 Binding of TLR4 and NOD2 1 0.36 0.51 0.57
119 INT236783 IRF6 Negative_regulation of Gene_expression of TLR4 1 0.01 1.17 0.57
120 INT306330 Cd14 Positive_regulation of Gene_expression of Tlr4 1 0.48 0.54 0.57
121 INT147201 Binding of CCL2 and Hsp70-2os 1 0.00 0.76 0.57
122 INT146871 Tlr4 Positive_regulation of Gene_expression of ROS1 2 0.00 1.16 0.56
123 INT81303 Tlr4 Positive_regulation of Gene_expression of Hmox1 1 0.03 0.55 0.56
124 INT94745 Tlr4 Positive_regulation of Transcription of Il1b 1 0.15 0.48 0.56
125 INT175323 Tlr4 Positive_regulation of Gene_expression of TLR2 1 0.02 0.31 0.56
126 INT120143 Tlr4 Negative_regulation of Gene_expression of Tnf 1 0.18 0.76 0.55
127 INT243056 Binding of LBP and Tlr4 1 0.00 1.11 0.55
128 INT310767 Tlr4 Regulation of Gene_expression of S100a8 1 0.02 0.7 0.54
129 INT210934 Gene_expression of Tlr4 Negative_regulation of Ccl2 1 0.47 0.69 0.54
130 INT354367 Binding of FGFR1 and Tlr4 1 0.01 1.23 0.53
131 INT253767 Binding of Hmgb1 and Tlr9 2 0.12 1.78 0.52
132 INT179503 Cd14 Regulation of Positive_regulation of Tlr4 1 0.38 0.58 0.52
133 INT343838 EDA Positive_regulation of TLR4 1 0.11 0.87 0.51
134 INT285911 Binding of TLR4 and Cd14 1 0.05 1.13 0.51
135 INT324523 Tlr4 Regulation of Gene_expression of PGE 1 0.23 1.98 0.51
136 INT179507 Tlr4 Positive_regulation of Tlr2 2 0.17 1.07 0.49
137 INT306019 Binding of Tlr4 and LY96 1 0.06 0.91 0.49
138 INT254119 Binding of Bcl2a1a and Tlr4 1 0.01 1.34 0.49
139 INT295708 Binding of EGF and CCL2 1 0.01 0.79 0.49
140 INT292814 Binding of VEGFA and Kdr 8 0.18 3.63 0.48
141 INT209046 Slc11a1 Positive_regulation of Regulation of Tlr4 1 0.07 0.09 0.48
142 INT114297 Apc Negative_regulation of Gene_expression of Fcer2a 1 0.03 0.96 0.48
143 INT244319 Csf2 Positive_regulation of Positive_regulation of Tlr4 1 0.23 1.03 0.48
144 INT263977 PROC Negative_regulation of JAK2 1 0.00 0.93 0.47
145 INT322264 Binding of MPZ and TLR4 1 0.18 1.68 0.47
146 INT134048 Jak2 Regulation of Pik3cb 1 0.23 0.13 0.47
147 INT233527 Tlr4 Positive_regulation of ADORA1 1 0.00 0.45 0.47
148 INT134045 Jak2 Regulation of Stat3 1 0.26 0.13 0.47
149 INT134042 Jak2 Regulation of Akt1 1 0.18 0.13 0.47
150 INT233503 Tlr4 Positive_regulation of Adora2b 1 0.06 0.45 0.47
151 INT134046 Jak2 Regulation of Gsk3b 1 0.22 0.13 0.47
152 INT217040 Negative_regulation of IRF6 Positive_regulation of CCL2 1 0.00 1.24 0.47
153 INT284300 Tlr4 Positive_regulation of Gene_expression of Mir155 1 0.18 0.91 0.47
154 INT217039 IRF6 Positive_regulation of CCL2 1 0.00 1.24 0.47
155 INT134050 Positive_regulation of Jak2 Regulation of Stat3 1 0.44 0.13 0.47
156 INT246938 Binding of Tlr4 and Tlr2 3 0.39 2.88 0.46
157 INT207141 Tlr4 Positive_regulation of Positive_regulation of Pawr 1 0.05 0.79 0.46
158 INT146506 Regulation of Gfap Regulation of Gene_expression of Ccl2 1 0.08 0.7 0.46
159 INT233508 Tlr4 Regulation of Gene_expression of Gpr18 1 0.04 0.45 0.46
160 INT310769 Pam Regulation of Tlr4 1 0.01 0.69 0.46
161 INT296795 Binding of Tlr9 and Tlr3 2 0.22 1.29 0.45
162 INT329794 TLR2 Positive_regulation of Positive_regulation of IL12A 1 0.01 1.05 0.44
163 INT69163 Tlr4 Positive_regulation of Ptgs1 1 0.02 0.08 0.44
164 INT230461 Binding of TLR1 and TLR2 3 0.33 2.06 0.43
165 INT112800 CASP1 Positive_regulation of Gene_expression of CCL2 1 0.04 0.48 0.43
166 INT184543 Agt Positive_regulation of Ccl2 1 0.16 3.18 0.43
167 INT254636 Bdkrb2 Regulation of Gene_expression of Ccl2 1 0.15 1.15 0.43
168 INT345288 AGT Positive_regulation of Localization of CCL2 1 0.01 1.5 0.43
169 INT212810 Tlr4 Positive_regulation of Gene_expression of Nos2 1 0.03 0.74 0.43
170 INT345291 AGT Positive_regulation of CCL2 1 0.01 1.39 0.43
171 INT332248 Ccl2 Positive_regulation of Ctgf 1 0.04 1.13 0.42
172 INT247599 Tlr4 Positive_regulation of Gene_expression of App 1 0.17 0.39 0.42
173 INT308696 Binding of Tlr4 and Tlr4 1 0.00 0.34 0.42
174 INT185381 TNF Regulation of TLR2 2 0.31 1.9 0.41
175 INT336926 Mir341 Regulation of Tlr4 1 0.02 1.57 0.41
176 INT329803 TLR2 Positive_regulation of Positive_regulation of IL6 1 0.01 0.94 0.41
177 INT329800 TLR2 Positive_regulation of Positive_regulation of IL8 1 0.01 0.99 0.41
178 INT348790 Binding of MYD88 and Tlr4 1 0.35 1.84 0.4
179 INT238384 Tlr4 Positive_regulation of Prkca 1 0.06 0.81 0.4
180 INT295478 IRF6 Positive_regulation of Positive_regulation of TLR4 2 0.20 0.78 0.39
181 INT222418 Tlr4 Positive_regulation of Gene_expression of Il1a 1 0.00 0.31 0.39
182 INT152238 Mapk14 Positive_regulation of Localization of Tlr4 1 0.29 0.13 0.39
183 INT237414 Binding of Jak2 and Bace1 1 0.20 0.77 0.39
184 INT152237 Mapk1 Positive_regulation of Localization of Tlr4 1 0.33 0.13 0.39
185 INT81300 Tlr4 Positive_regulation of Gene_expression of Nos2 1 0.02 0.38 0.39
186 INT260744 Binding of Ecm1 and Tlr2 1 0.00 0.45 0.39
187 INT310697 Tlr4 Positive_regulation of Gene_expression of Ptger2 2 0.03 1.34 0.38
188 INT339504 Binding of Irak1 and Tlr4 1 0.08 0.12 0.38
189 INT204893 Regulation of Tlr4 Positive_regulation of gr 1 0.11 0.9 0.38
190 INT260746 Binding of TLR4 and Ecm1 1 0.02 0.44 0.38
191 INT147969 Binding of Ly86 and Tlr4 1 0.30 0.37 0.38
192 INT260747 Binding of TLR4 and Tlr2 1 0.05 0.44 0.38
193 INT215275 Tlr4 Positive_regulation of Gene_expression of Ros1 1 0.01 1.37 0.38
194 INT339511 Binding of Tlr4 and Traf6 1 0.05 0.12 0.38
195 INT339512 Negative_regulation of Binding of Tlr4 and Traf6 1 0.05 0.17 0.38
196 INT188560 Negative_regulation of Binding of IRF6 and TLR4 1 0.04 0.58 0.38
197 INT204905 Tlr4 Positive_regulation of gr 1 0.18 0.9 0.38
198 INT328828 Binding of Jak2 and Jak1 1 0.24 0 0.38
199 INT328827 Binding of Jak2 and Il6st 1 0.05 0 0.38
200 INT328820 Binding of Il6 and Jak2 1 0.09 0 0.38

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of nitric-oxide synthase biosynthetic process. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of nitric-oxide synthase biosynthetic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT55879 Gene_expression of CCL2 421 0.78 240.74 166.02
2 INT7533 Gene_expression of Tlr4 720 0.78 343.22 121.57
3 INT82878 Gene_expression of Ccl2 201 0.78 164.95 101.35
4 INT102546 Gene_expression of Ccl2 197 0.78 192.8 67.41
5 INT1951 Positive_regulation of Tlr4 345 0.70 176.99 62.42
6 INT67981 Positive_regulation of CCL2 165 0.70 136.84 61.85
7 INT117223 Gene_expression of TLR4 348 0.78 206.18 54.42
8 INT81498 Positive_regulation of Gene_expression of CCL2 107 0.70 53.89 45.22
9 INT82883 Positive_regulation of Ccl2 105 0.69 84.96 42.27
10 INT133028 Gene_expression of TLR2 209 0.73 131.92 36.17
11 INT81289 Positive_regulation of Gene_expression of Tlr4 192 0.69 104.5 33.89
12 INT65698 Localization of CCL2 118 0.81 77.54 32.69
13 INT84170 Positive_regulation of Gene_expression of Ccl2 58 0.69 48.79 32.43
14 INT56809 Binding of Tlr4 184 0.48 106.02 31.18
15 INT118734 Gene_expression of Tlr4 70 0.78 55.7 28.19
16 INT82882 Localization of Ccl2 61 0.80 41.96 28
17 INT134651 Binding of TLR4 89 0.48 66.96 23.19
18 INT142594 Gene_expression of Tlr2 165 0.78 139.73 22.26
19 INT78057 Localization of Tlr4 140 0.77 67.75 21.72
20 INT7535 Negative_regulation of Tlr4 111 0.56 56.84 21.37
21 INT138696 Positive_regulation of Ccl2 57 0.67 59.57 19.58
22 INT66857 Regulation of CCL2 39 0.53 28.55 18.35
23 INT84171 Negative_regulation of Gene_expression of Ccl2 30 0.58 26.37 18.28
24 INT55880 Negative_regulation of Gene_expression of CCL2 49 0.59 22.37 18.09
25 INT55878 Regulation of Gene_expression of CCL2 34 0.62 15.71 17.97
26 INT113602 Positive_regulation of Gene_expression of Ccl2 48 0.70 48.71 17.85
27 INT117220 Positive_regulation of TLR4 64 0.69 53.61 17.33
28 INT43906 Regulation of Tlr4 71 0.53 35.18 15.49
29 INT67641 Negative_regulation of Gene_expression of Tlr4 90 0.58 46 14.6
30 INT151120 Negative_regulation of Tlr4 18 0.59 21.09 14.46
31 INT142593 Positive_regulation of Tlr2 85 0.70 75.9 13.62
32 INT117222 Positive_regulation of Gene_expression of TLR4 80 0.70 51.6 12.9
33 INT96850 Negative_regulation of CCL2 42 0.59 24.89 12.55
34 INT149985 Gene_expression of Tlr9 32 0.75 29.83 11.86
35 INT118742 Positive_regulation of Tlr4 32 0.69 27.55 11.09
36 INT133030 Positive_regulation of Gene_expression of TLR2 53 0.65 38.15 10.65
37 INT150540 Binding of TLR2 50 0.45 35.86 10.43
38 INT134625 Gene_expression of Kdr 116 0.71 53.13 10.09
39 INT83450 Positive_regulation of Localization of CCL2 28 0.70 22.14 9.83
40 INT106200 Binding of Ccl2 22 0.42 16.7 9.75
41 INT135407 Negative_regulation of Ccl2 33 0.57 32.74 9.45
42 INT140224 Localization of Ccl2 32 0.72 26.91 9.39
43 INT138700 Negative_regulation of Gene_expression of Ccl2 27 0.57 24.1 9.08
44 INT182137 Gene_expression of TLR9 137 0.78 48.48 9.05
45 INT146991 Positive_regulation of Gene_expression of Tlr4 21 0.69 20.76 8.69
46 INT1952 Negative_regulation of Positive_regulation of Tlr4 33 0.51 15.8 7.41
47 INT39417 Gene_expression of Fcer2a 65 0.76 32.1 7.37
48 INT103909 Gene_expression of NOD2 37 0.77 21.9 7.36
49 INT82881 Regulation of Ccl2 19 0.57 15.29 7.19
50 INT1950 Positive_regulation of Positive_regulation of Tlr4 38 0.49 20.17 7.14
51 INT295467 Negative_regulation of Gene_expression of Tlr4 11 0.58 7.94 6.83
52 INT81493 Transcription of CCL2 20 0.65 13.63 6.78
53 INT142596 Positive_regulation of Gene_expression of Tlr2 42 0.69 38.41 6.67
54 INT207892 Binding of Tlr9 35 0.46 26.66 6.61
55 INT120895 Binding of CCL2 22 0.37 15.86 6.55
56 INT137206 Positive_regulation of TLR2 47 0.65 33.36 6.4
57 INT92504 Negative_regulation of Ccl2 17 0.43 8.98 6.29
58 INT97797 Localization of TLR4 18 0.77 13.78 6
59 INT103760 Regulation of Gene_expression of Tlr4 35 0.59 16.26 5.95
60 INT143158 Negative_regulation of Gene_expression of TLR4 31 0.56 20.62 5.69
61 INT83290 Regulation of Gene_expression of Ccl2 8 0.59 9.06 5.56
62 INT168279 Regulation of Tlr4 17 0.54 8.97 5.5
63 INT142595 Negative_regulation of Tlr2 24 0.52 19.17 5.43
64 INT140223 Regulation of Ccl2 15 0.45 13.1 5.41
65 INT213741 Gene_expression of Kdr 60 0.75 44.24 5.35
66 INT174688 Binding of Tlr2 45 0.42 36.65 5.25
67 INT145767 Negative_regulation of TLR4 18 0.43 11.03 5.25
68 INT145756 Gene_expression of Tlr2 23 0.74 20.77 5.18
69 INT157622 Positive_regulation of Localization of Tlr4 34 0.48 22.63 5.09
70 INT161220 Binding of Ccl2 17 0.46 17.63 4.94
71 INT113161 Gene_expression of Jak2 50 0.77 42.52 4.76
72 INT108919 Positive_regulation of Mapk9 9 0.34 3.55 4.74
73 INT185398 Negative_regulation of Gene_expression of TLR2 34 0.55 27.21 4.73
74 INT2725 Positive_regulation of FCER2 23 0.69 23.08 4.7
75 INT103073 Positive_regulation of Positive_regulation of Ccl2 10 0.50 6.74 4.7
76 INT96851 Negative_regulation of Localization of CCL2 14 0.53 5.98 4.57
77 INT188672 Positive_regulation of Tlr9 15 0.67 13.1 4.48
78 INT103155 Gene_expression of KDR 78 0.66 50.53 4.38
79 INT149986 Positive_regulation of Gene_expression of Tlr9 5 0.67 8.18 4.15
80 INT204529 Positive_regulation of TLR9 18 0.62 15.62 3.99
81 INT153410 Negative_regulation of Jak2 5 0.59 10.71 3.98
82 INT186808 Transcription of TLR4 22 0.69 12.77 3.73
83 INT104480 Phosphorylation of Mapk9 8 0.80 6.59 3.62
84 INT117518 Transcription of Ccl2 12 0.68 11.12 3.61
85 INT143159 Regulation of Gene_expression of TLR4 28 0.62 15.08 3.54
86 INT264970 Positive_regulation of Localization of TLR2 1 0.11 4.21 3.37
87 INT181355 Regulation of Gene_expression of Ccl2 12 0.44 10.37 3.21
88 INT178711 Protein_catabolism of Tlr4 15 0.84 6.75 3.19
89 INT135409 Transcription of Ccl2 13 0.62 10.59 3.06
90 INT186805 Transcription of TLR2 12 0.63 9.66 3.04
91 INT145768 Regulation of TLR4 19 0.45 8.31 2.96
92 INT185315 Transcription of Tlr4 24 0.69 8.65 2.93
93 INT103910 Binding of NOD2 19 0.47 12.24 2.93
94 INT50765 Positive_regulation of Fcer2a 23 0.68 10.22 2.92
95 INT260424 Negative_regulation of Tlr9 8 0.41 8.19 2.92
96 INT306949 Gene_expression of NAMPT 27 0.67 24.47 2.86
97 INT204524 Binding of TLR9 17 0.43 11.69 2.76
98 INT133029 Regulation of TLR2 18 0.56 11.31 2.62
99 INT186799 Localization of TLR2 5 0.68 2.51 2.58
100 INT113160 Negative_regulation of Jak2 26 0.58 20.3 2.57
101 INT117519 Positive_regulation of Transcription of Ccl2 5 0.49 6.01 2.54
102 INT32421 Gene_expression of FCER2 19 0.73 17.23 2.53
103 INT100086 Negative_regulation of Localization of Tlr4 15 0.37 5.92 2.47
104 INT113339 Binding of JAK2 6 0.40 5.31 2.4
105 INT184063 Positive_regulation of Jak2 17 0.69 10.97 2.37
106 INT82880 Positive_regulation of Localization of Ccl2 4 0.49 2.65 2.31
107 INT134626 Positive_regulation of Gene_expression of Kdr 20 0.63 14.63 2.29
108 INT72890 Positive_regulation of Gene_expression of Fcer2a 12 0.17 6.81 2.25
109 INT204775 Regulation of Tlr2 21 0.41 13.6 2.18
110 INT113906 Regulation of Positive_regulation of CCL2 4 0.27 3.2 2.17
111 INT118871 Negative_regulation of JAK2 15 0.57 11.4 2.16
112 INT128993 Negative_regulation of Localization of Ccl2 1 0.42 1.5 2.1
113 INT154751 Positive_regulation of Positive_regulation of Ccl2 2 0.48 2.43 2.06
114 INT113907 Regulation of Localization of CCL2 5 0.62 2.46 2.05
115 INT108921 Negative_regulation of Positive_regulation of Mapk9 3 0.25 1.8 1.99
116 INT222609 Binding of Tlr4 8 0.43 4.03 1.98
117 INT107448 Positive_regulation of Jak2 8 0.50 5.33 1.98
118 INT100490 Negative_regulation of Positive_regulation of CCL2 6 0.23 1.48 1.96
119 INT326816 Negative_regulation of Positive_regulation of Tlr4 2 0.59 3.96 1.95
120 INT141002 Negative_regulation of Fcer2a 15 0.12 7.17 1.88
121 INT295469 Localization of Tlr4 3 0.75 2.22 1.88
122 INT136503 Negative_regulation of KDR 46 0.48 43.1 1.86
123 INT67980 Positive_regulation of Positive_regulation of CCL2 7 0.49 5.89 1.85
124 INT117221 Positive_regulation of Gene_expression of NOD2 7 0.65 4.39 1.83
125 INT104478 Positive_regulation of Mapk9 5 0.67 5.56 1.81
126 INT162725 Binding of Kdr 13 0.42 8.86 1.79
127 INT162793 Regulation of NOD2 6 0.45 7.61 1.78
128 INT301954 Regulation of Negative_regulation of Tlr4 1 0.45 2.46 1.77
129 INT191862 Phosphorylation of Tlr4 17 0.79 6.89 1.74
130 INT228195 Negative_regulation of Gene_expression of Tlr2 14 0.40 12.17 1.74
131 INT104479 Negative_regulation of Mapk9 3 0.37 2.83 1.69
132 INT188584 Positive_regulation of Positive_regulation of TLR4 8 0.65 5.98 1.64
133 INT113340 Phosphorylation of JAK2 17 0.78 5.69 1.6
134 INT142678 Positive_regulation of Phosphorylation of Mapk9 4 0.51 2.1 1.6
135 INT53343 Positive_regulation of NAMPT 13 0.60 10.94 1.58
136 INT175307 Regulation of Gene_expression of TLR2 9 0.56 7.08 1.58
137 INT153409 Negative_regulation of Negative_regulation of Jak2 2 0.34 1.01 1.52
138 INT204530 Positive_regulation of Gene_expression of TLR9 14 0.70 6.85 1.48
139 INT142676 Phosphorylation of Mapk9 5 0.61 1.48 1.48
140 INT322712 Negative_regulation of Binding of Ccl2 4 0.32 1.29 1.44
141 INT174683 Transcription of Tlr2 12 0.58 5.95 1.4
142 INT29986 Binding of Fcer2a 9 0.27 4.34 1.38
143 INT159784 Gene_expression of Mapk9 8 0.61 6.28 1.37
144 INT134041 Phosphorylation of Jak2 6 0.75 3.71 1.37
145 INT142679 Negative_regulation of Phosphorylation of Mapk9 1 0.17 0.51 1.37
146 INT199567 Binding of Kdr 18 0.47 13.81 1.34
147 INT90226 Gene_expression of Mapk9 3 0.65 1.94 1.34
148 INT117219 Positive_regulation of NOD2 9 0.69 4.66 1.31
149 INT204766 Gene_expression of Nod2 4 0.75 4.14 1.3
150 INT221131 Localization of Tlr2 17 0.80 13.82 1.28
151 INT179497 Positive_regulation of Binding of Tlr4 12 0.50 6.49 1.27
152 INT151567 Gene_expression of Tlr9 6 0.72 3.63 1.26
153 INT81497 Positive_regulation of Transcription of CCL2 4 0.63 2 1.25
154 INT146914 Negative_regulation of TLR2 12 0.53 7.41 1.23
155 INT114294 Negative_regulation of Gene_expression of Fcer2a 7 0.14 4.09 1.23
156 INT228772 Positive_regulation of Localization of Ccl2 3 0.48 4.23 1.21
157 INT105270 Positive_regulation of KDR 25 0.49 11.49 1.2
158 INT190804 Positive_regulation of Tlr2 6 0.66 3.7 1.16
159 INT152225 Regulation of Positive_regulation of Tlr4 8 0.53 2.5 1.12
160 INT294735 Positive_regulation of Binding of Ccl2 2 0.34 0.69 1.11
161 INT140054 Negative_regulation of Mapk9 3 0.25 1.9 1.05
162 INT205912 Negative_regulation of Gene_expression of Jak2 8 0.42 5.1 1.04
163 INT29985 Positive_regulation of Binding of Fcer2a 1 0.00 0 1.04
164 INT200556 Regulation of Kdr 8 0.28 6.04 1.01
165 INT118738 Transcription of Tlr4 4 0.70 1.39 1
166 INT260471 Positive_regulation of Gene_expression of Kdr 9 0.61 8.37 0.99
167 INT154227 Regulation of Gene_expression of NOD2 3 0.44 3.38 0.99
168 INT198049 Positive_regulation of JAK2 16 0.58 5.35 0.96
169 INT288493 Positive_regulation of Gene_expression of Tlr2 4 0.66 4.38 0.94
170 INT275510 Negative_regulation of Binding of Ccl2 3 0.32 1.47 0.93
171 INT169336 Binding of Jak2 2 0.42 1.31 0.93
172 INT134040 Regulation of Jak2 3 0.41 1.07 0.92
173 INT145760 Binding of Tlr2 5 0.46 3.59 0.89
174 INT295466 Positive_regulation of Regulation of Tlr4 2 0.44 1.33 0.89
175 INT168278 Positive_regulation of Phosphorylation of Tlr4 1 0.48 1.05 0.88
176 INT188575 Positive_regulation of Transcription of TLR2 1 0.30 1.37 0.88
177 INT168277 Phosphorylation of Tlr4 1 0.78 1.05 0.88
178 INT184027 Phosphorylation of Jak2 6 0.82 2.58 0.87
179 INT208243 Positive_regulation of Phosphorylation of Tlr4 5 0.31 3.74 0.86
180 INT134037 Positive_regulation of Phosphorylation of Jak2 1 0.46 0.25 0.86
181 INT196583 Regulation of Phosphorylation of Mapk9 1 0.37 0.5 0.85
182 INT104482 Positive_regulation of Phosphorylation of Mapk9 2 0.49 1.55 0.84
183 INT146567 Negative_regulation of Negative_regulation of Ccl2 1 0.43 1.72 0.83
184 INT173100 Binding of KDR 39 0.39 22.48 0.81
185 INT238201 Gene_expression of JAK2 9 0.70 7.09 0.81
186 INT67797 Localization of Fcer2a 2 0.51 0.06 0.81
187 INT117552 Regulation of Regulation of CCL2 1 0.13 0.57 0.8
188 INT297469 Regulation of Binding of Kdr 1 0.54 2.01 0.8
189 INT237408 Positive_regulation of Positive_regulation of Jak2 1 0.28 1.56 0.79
190 INT200855 Positive_regulation of Kdr 14 0.45 11.14 0.77
191 INT188582 Positive_regulation of Transcription of TLR4 2 0.50 4.07 0.77
192 INT295465 Regulation of Positive_regulation of Tlr4 2 0.39 1.28 0.75
193 INT151128 Positive_regulation of Negative_regulation of Tlr4 2 0.46 1 0.75
194 INT294787 Localization of TLR9 2 0.67 2.35 0.75
195 INT306954 Binding of NAMPT 8 0.36 7.98 0.74
196 INT224630 Positive_regulation of Positive_regulation of Tlr2 6 0.46 4.14 0.73
197 INT113342 Positive_regulation of Phosphorylation of JAK2 2 0.66 2.58 0.72
198 INT104488 Negative_regulation of Phosphorylation of Mapk9 1 0.41 1.03 0.72
199 INT306951 Positive_regulation of Gene_expression of NAMPT 1 0.60 6.08 0.72
200 INT120010 Negative_regulation of Transcription of CCL2 1 0.02 0.99 0.72
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