GO:0051797

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Name regulation of hair follicle development
Categary Process
Go Slim No
Go Link GO:0051797
Unique Molecular Interactions 37
Total Molecular Interactions 41
Total Single Events 439
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for regulation of hair follicle development. They are ordered first by their pain relevance and then by number of times they were reported for regulation of hair follicle development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT70946 Penk Positive_regulation of Hpse 1 0.34 0 2.65
2 INT109958 Binding of CRH and HPSE 1 0.10 0.72 1.46
3 INT70947 Penk Regulation of Hpse 1 0.20 0 0.96
4 INT220145 HPSE Negative_regulation of Gene_expression of CRH 1 0.01 0.92 0.64
5 INT352387 Binding of CFP and HPSE 1 0.01 1.25 0.46
6 INT177440 Binding of HPSE and Gnrh1 1 0.00 1.82 0.45
7 INT245640 Nr3c2 Regulation of Positive_regulation of Hpse 1 0.08 0.66 0.26
8 INT319555 gr Positive_regulation of Positive_regulation of Hpse 1 0.09 0.11 0.22
9 INT222499 Il10 Regulation of Positive_regulation of Hpse 1 0.00 0.8 0.19
10 INT222531 Il6 Positive_regulation of Hpse 1 0.00 0.61 0.18
11 INT222414 Tlr4 Positive_regulation of Hpse 1 0.00 0.61 0.18
12 INT333449 Binding of SMAD2 and SMAD4 1 0.23 0 0.17
13 INT245641 Nr3c2 Regulation of Gene_expression of Hpse 1 0.14 2.67 0.17
14 INT222505 Gene_expression of Crh Negative_regulation of Gene_expression of Hpse 1 0.02 0.55 0.17
15 INT222420 Tlr4 Positive_regulation of Positive_regulation of Hpse 1 0.00 0.67 0.15
16 INT222551 Il6 Positive_regulation of Positive_regulation of Hpse 1 0.01 0.5 0.13
17 INT311191 ecs Negative_regulation of HPSE 1 0.00 0.94 0.12
18 INT172976 Mras Regulation of Gene_expression of Smad4 1 0.00 0.83 0.12
19 INT341879 Oxt Negative_regulation of Positive_regulation of Hpse 1 0.01 0.83 0.11
20 INT186539 Crh Regulation of Hpse 1 0.09 0.52 0.1
21 INT186540 Binding of Cort and Hpse 1 0.05 0.92 0.08
22 INT245642 Nr3c1 Regulation of Gene_expression of Hpse 1 0.05 1.33 0.08
23 INT159461 SCN5A Negative_regulation of HPSE 1 0.00 0 0.07
24 INT159463 Ptprn2 Negative_regulation of HPSE 1 0.00 0 0.07
25 INT330487 Binding of MME and HPSE 1 0.35 0 0.06
26 INT311906 Binding of Smad4 and Insrr 1 0.00 0.18 0.06
27 INT353290 Binding of Smad2 and Smad4 1 0.20 0.08 0.04
28 INT353295 Binding of Smad3 and Smad4 1 0.17 0.08 0.04
29 INT280263 Binding of Smad4 and Proc 1 0.00 1.26 0.03
30 INT277927 WIF1 Negative_regulation of SMAD4 1 0.23 0.37 0
31 INT185733 Hpse Positive_regulation of Gene_expression of Tnfrsf11b 1 0.20 0.24 0
32 INT268341 SMAD2 Positive_regulation of SMAD4 1 0.31 0.56 0
33 INT162510 Binding of ITPR1 and HPSE 1 0.02 0.05 0
34 INT317597 Binding of Gnrh1 and Hpse 1 0.08 0 0
35 INT222537 Binding of Nmu and Hpse 1 0.01 0.15 0
36 INT268344 SMAD3 Positive_regulation of SMAD4 1 0.17 0.56 0
37 INT172981 PAN3 Negative_regulation of SMAD4 1 0.01 0.98 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for regulation of hair follicle development. They are ordered first by their pain relevance and then by number of times they were reported in regulation of hair follicle development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT13415 Positive_regulation of Hpse 58 0.70 24.9 25.53
2 INT12575 Regulation of Hpse 33 0.59 17.7 18.45
3 INT49474 Gene_expression of Hpse 24 0.55 20.11 10.03
4 INT65554 Positive_regulation of Hpse 13 0.69 8.16 5.17
5 INT30014 Positive_regulation of HPSE 22 0.70 20.91 4.09
6 INT68978 Regulation of Positive_regulation of Hpse 6 0.45 1.88 4.02
7 INT61734 Regulation of HPSE 16 0.60 13.05 3.5
8 INT13321 Negative_regulation of Hpse 11 0.56 4.64 3.39
9 INT69621 Positive_regulation of Positive_regulation of Hpse 7 0.42 4.1 2.85
10 INT96338 Gene_expression of HPSE 17 0.75 18.71 2.73
11 INT13414 Regulation of Regulation of Hpse 4 0.16 1.71 2.55
12 INT175797 Regulation of Gene_expression of Hpse 6 0.07 6.52 2.49
13 INT107178 Gene_expression of Smad4 12 0.65 9.85 1.92
14 INT74707 Negative_regulation of Hpse 4 0.58 2.29 1.73
15 INT33591 Negative_regulation of Positive_regulation of Hpse 6 0.32 3.42 1.63
16 INT129492 Gene_expression of Hpse 11 0.75 6.56 1.59
17 INT74955 Negative_regulation of HPSE 6 0.57 4.75 1.57
18 INT65553 Regulation of Hpse 6 0.27 3.89 1.37
19 INT148638 Protein_catabolism of Hpse 1 0.48 1.09 1.28
20 INT175794 Negative_regulation of Gene_expression of Hpse 2 0.12 1.82 1.08
21 INT96229 Localization of HPSE 3 0.20 2.76 1.05
22 INT55580 Localization of Hpse 5 0.23 3.51 0.89
23 INT109854 Negative_regulation of Positive_regulation of Hpse 1 0.23 0 0.81
24 INT65552 Binding of Hpse 2 0.30 2.48 0.8
25 INT172960 Negative_regulation of Gene_expression of Smad4 7 0.39 5.88 0.71
26 INT96339 Protein_catabolism of HPSE 5 0.96 2.87 0.63
27 INT317596 Positive_regulation of Gene_expression of Hpse 3 0.14 2.24 0.6
28 INT129493 Protein_catabolism of Hpse 2 0.55 2.81 0.57
29 INT103781 Negative_regulation of Smad4 9 0.42 4.42 0.54
30 INT177436 Binding of HPSE 2 0.47 1.81 0.52
31 INT190590 Localization of Hpse 2 0.28 0.49 0.48
32 INT71019 Negative_regulation of SMAD4 12 0.42 6.88 0.43
33 INT177437 Transcription of HPSE 2 0.23 3.44 0.41
34 INT84900 Positive_regulation of Localization of Hpse 1 0.16 0.16 0.41
35 INT319548 Positive_regulation of Localization of Hpse 1 0.17 0.08 0.38
36 INT117564 Gene_expression of SMAD4 12 0.71 8.7 0.37
37 INT129494 Regulation of Gene_expression of Hpse 2 0.23 1.36 0.36
38 INT129495 Negative_regulation of Gene_expression of Hpse 1 0.36 0.52 0.36
39 INT74954 Positive_regulation of Positive_regulation of HPSE 2 0.40 0.45 0.34
40 INT55582 Positive_regulation of Negative_regulation of Hpse 2 0.13 0.56 0.32
41 INT177439 Negative_regulation of Positive_regulation of HPSE 1 0.21 1.48 0.32
42 INT92100 Binding of Smad4 5 0.31 2.23 0.3
43 INT175796 Binding of Hpse 6 0.35 2.19 0.28
44 INT96337 Positive_regulation of Gene_expression of HPSE 1 0.67 2.28 0.25
45 INT277935 Binding of SMAD4 4 0.28 1.12 0.17
46 INT139977 Regulation of Smad4 1 0.16 1.41 0.15
47 INT145276 Transcription of Hpse 1 0.53 0.65 0.14
48 INT145275 Regulation of Transcription of Hpse 1 0.27 0.65 0.14
49 INT325510 Transcription of Smad4 1 0.67 0.16 0.09
50 INT74953 Positive_regulation of Regulation of HPSE 2 0.49 1.02 0.07
51 INT118191 Regulation of Regulation of HPSE 2 0.26 0.87 0.07
52 INT254790 Localization of Smad4 2 0.37 0.54 0.06
53 INT347453 Negative_regulation of Regulation of Hpse 1 0.12 0.3 0.04
54 INT334291 Positive_regulation of Gene_expression of SMAD4 1 0.18 0 0.04
55 INT268360 Positive_regulation of SMAD4 3 0.55 1.55 0.03
56 INT349102 Positive_regulation of Gene_expression of Hpse 1 0.03 0.21 0.03
57 INT117563 Negative_regulation of Gene_expression of SMAD4 6 0.54 3.87 0
58 INT334327 Regulation of SMAD4 2 0.35 1.73 0
59 INT268368 Transcription of SMAD4 1 0.54 1.7 0
60 INT173000 Negative_regulation of Localization of SMAD4 1 0.22 0.98 0
61 INT173008 Localization of SMAD4 1 0.38 0.97 0
62 INT296566 Regulation of Binding of Hpse 1 0.02 0.84 0
63 INT334289 Regulation of Binding of SMAD4 1 0.16 0 0
64 INT334288 Regulation of Negative_regulation of SMAD4 1 0.16 0 0
65 INT228250 Positive_regulation of Smad4 1 0.45 1.93 0
66 INT335965 Negative_regulation of Localization of HPSE 1 0.11 0.93 0
67 INT228247 Regulation of Positive_regulation of Smad4 1 0.26 0.97 0
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