GO:0051799

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Name negative regulation of hair follicle development
Categary Process
Go Slim No
Go Link GO:0051799
Unique Molecular Interactions 80
Total Molecular Interactions 128
Total Single Events 636
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of hair follicle development. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of hair follicle development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT73539 Binding of Ngf and Ngfr 5 0.45 3.99 4
2 INT222335 Binding of Bdnf and Ngfr 3 0.05 2.66 1.48
3 INT280480 Binding of Bdnf and Ngfr 5 0.25 3.14 1.27
4 INT256041 Binding of Ngfr and Ntrk1 3 0.14 0.9 1.13
5 INT82024 Binding of Ngfr and Ngf 2 0.33 1.48 1.05
6 INT76001 Ngf Positive_regulation of Ngfr 1 0.16 0.93 1.05
7 INT242642 Binding of BDNF and Ngfr 2 0.21 1.38 1.01
8 INT127672 Binding of NGFR and NTRK1 1 0.17 2.28 0.97
9 INT73538 Ngf Positive_regulation of Ngfr 2 0.41 1.05 0.85
10 INT213726 Binding of Ngfr and Ntrk1 1 0.14 0.96 0.72
11 INT289333 Binding of Ngfr and Rtn4r 1 0.03 2.35 0.72
12 INT289332 Binding of Ngfr and Lingo1 1 0.04 2.36 0.72
13 INT82021 Negative_regulation of Binding of Ngfr and Ngf 1 0.29 0.32 0.69
14 INT289357 Ngfr Positive_regulation of Akt1 1 0.03 3.1 0.66
15 INT297340 Apoe Regulation of Binding of Smo 1 0.10 1.1 0.6
16 INT134532 Grin2a Regulation of Ngfr 1 0.02 0 0.57
17 INT134528 Grin1 Regulation of Ngfr 1 0.03 0 0.57
18 INT134531 Gria1 Regulation of Ngfr 1 0.01 0 0.57
19 INT76002 Ngf Positive_regulation of Ngfr 1 0.05 0.48 0.53
20 INT245558 Runx3 Regulation of Ngfr 1 0.06 1 0.53
21 INT127677 NGF Regulation of Gene_expression of NGFR 1 0.20 1.11 0.5
22 INT161227 Binding of Ngfr and Tnf 1 0.06 0.41 0.49
23 INT120295 Ngf Positive_regulation of Positive_regulation of Ngfr 1 0.47 0.22 0.43
24 INT73537 Ntf3 Positive_regulation of Ngfr 1 0.21 0.1 0.38
25 INT73536 Ngf Regulation of Ngfr 1 0.22 0.08 0.37
26 INT112283 Bdnf Regulation of Gene_expression of Ngfr 1 0.14 0.28 0.34
27 INT297342 Binding of Gnb5 and Smo 1 0.02 1.67 0.34
28 INT241451 Mag Positive_regulation of Ngfr 1 0.09 0.1 0.21
29 INT308654 Binding of Ngfr and Nts 1 0.06 0.39 0.21
30 INT280486 Binding of Ngfr and Ntrk2 2 0.18 1.21 0.17
31 INT160539 Binding of NGF and NGFR 1 0.06 0.46 0.17
32 INT160542 Binding of BDNF and NGFR 1 0.08 0.46 0.17
33 INT241462 Binding of OMG and Ngfr 1 0.11 0.15 0.15
34 INT241457 Binding of Mag and Ngfr 1 0.09 0.15 0.15
35 INT241453 Binding of Ngfr and Rtn4r 1 0.03 0.15 0.15
36 INT345343 PTCH1 Regulation of Negative_regulation of SMO 1 0.09 2.3 0.13
37 INT349858 Binding of Ngfr and Ntrk2 1 0.09 0.32 0.11
38 INT280493 Ngfr Regulation of Protein_catabolism of BDNF 1 0.09 0.14 0.1
39 INT262751 Binding of PTCH1 and SMO 1 0.25 1.29 0.1
40 INT164675 Binding of NGF and Ngfr 1 0.00 0.5 0.08
41 INT270464 Binding of Shh and Smo 1 0.07 1.3 0.08
42 INT164676 Negative_regulation of Binding of NGF and Ngfr 1 0.00 0.5 0.08
43 INT262757 SMO Positive_regulation of Regulation of GLI1 1 0.34 0.6 0.04
44 INT201766 Binding of RIPK2 and Ngfr 1 0.02 0.41 0.04
45 INT270458 Binding of Gli1 and Smo 1 0.00 0.65 0.04
46 INT241449 Mag Positive_regulation of Protein_catabolism of Ngfr 1 0.09 0 0.03
47 INT201732 Ngfr Positive_regulation of Nfkb1 1 0.01 0.43 0.03
48 INT200063 Binding of MAGED1 and Ngfr 1 0.44 0.45 0
49 INT205975 Binding of PTCH1 and Smo 1 0.02 0.72 0
50 INT338013 Binding of Ngfrap1 and Ngfr 1 0.06 1.3 0
51 INT200062 Binding of Ngfr and Bbs4 1 0.30 0.3 0
52 INT205974 Smo Positive_regulation of GLI1 1 0.04 0.66 0
53 INT352525 SLC25A16 Negative_regulation of SMO 1 0.00 1.1 0
54 INT200053 Binding of Nuc and Ngfr 1 0.10 0.3 0
55 INT200057 Binding of Ndn and Ngfr 1 0.43 1.96 0
56 INT320346 Binding of Ngfr and Np4 1 0.01 0 0
57 INT349543 Tnfsf10 Positive_regulation of NGFR 1 0.01 0.43 0
58 INT201742 Binding of Ngfr and Gtf3a 1 0.00 0.77 0
59 INT200061 Binding of Ngfr and Fez1 1 0.31 0.3 0
60 INT205965 Binding of Ptch1 and Smo 1 0.03 0.72 0
61 INT290372 Binding of Ngfr and Scarb1 1 0.01 0.48 0
62 INT201741 Binding of Rhoa and Ngfr 1 0.01 1 0
63 INT200055 Binding of Ngfr and Mageh1 1 0.33 0.45 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of hair follicle development. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of hair follicle development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT55908 Gene_expression of Ngfr 74 0.78 34.46 28.8
2 INT46016 Gene_expression of Ngfr 69 0.77 41.22 19.8
3 INT66038 Positive_regulation of Ngfr 32 0.69 26.07 11.75
4 INT75921 Negative_regulation of Ngfr 13 0.59 8.58 8.35
5 INT48310 Binding of Ngfr 25 0.48 9.72 8.16
6 INT61542 Positive_regulation of Ngfr 15 0.70 6.35 7.34
7 INT78713 Negative_regulation of Ngfr 9 0.54 7.07 6.73
8 INT96492 Gene_expression of NGFR 24 0.00 12.3 4.59
9 INT64711 Regulation of Ngfr 10 0.45 3.12 4.33
10 INT121170 Positive_regulation of Gene_expression of Ngfr 10 0.64 9.32 3.94
11 INT121171 Negative_regulation of Gene_expression of Ngfr 6 0.58 3.46 3.89
12 INT55907 Binding of Ngfr 13 0.47 5.79 3.75
13 INT12385 Localization of NGFR 6 0.81 3.05 3.47
14 INT61540 Negative_regulation of Gene_expression of Ngfr 11 0.59 6.36 3.43
15 INT61541 Positive_regulation of Gene_expression of Ngfr 7 0.53 2.87 2.75
16 INT75225 Transcription of Ngfr 4 0.60 1.95 2.44
17 INT64712 Localization of Ngfr 4 0.78 1.19 1.91
18 INT140247 Negative_regulation of Negative_regulation of Ngfr 3 0.33 3.15 1.59
19 INT163594 Regulation of Ngfr 5 0.43 2.55 1.53
20 INT127679 Positive_regulation of Gene_expression of NGFR 7 0.67 4.98 1.43
21 INT64713 Regulation of Gene_expression of Ngfr 4 0.50 2.04 1.36
22 INT138939 Positive_regulation of Transcription of Ngfr 3 0.43 0.89 1.31
23 INT137811 Negative_regulation of NGFR 4 0.50 2.22 1.28
24 INT56127 Positive_regulation of NGFR 8 0.49 5.3 1.27
25 INT164372 Positive_regulation of Positive_regulation of Ngfr 6 0.62 4.1 1.22
26 INT12386 Binding of NGFR 6 0.48 2.15 1.22
27 INT183068 Gene_expression of SMO 2 0.17 0.27 1.2
28 INT110392 Transcription of Ngfr 3 0.52 2.48 1.19
29 INT163595 Positive_regulation of Regulation of Ngfr 1 0.46 0.57 1.04
30 INT270447 Binding of Smo 2 0.07 2.61 0.78
31 INT143427 Regulation of NGFR 1 0.26 1.65 0.73
32 INT317733 Positive_regulation of Binding of Ngfr 1 0.18 0.51 0.71
33 INT133018 Regulation of Gene_expression of Ngfr 2 0.43 1.47 0.7
34 INT205957 Negative_regulation of Smo 4 0.08 2.57 0.6
35 INT139929 Phosphorylation of Ngfr 3 0.58 1.67 0.57
36 INT118729 Regulation of Transcription of Ngfr 1 0.36 0.45 0.57
37 INT110393 Positive_regulation of Transcription of Ngfr 1 0.46 1 0.54
38 INT165518 Positive_regulation of Regulation of Ngfr 2 0.47 0.47 0.37
39 INT127678 Transcription of NGFR 1 0.29 0.9 0.33
40 INT356400 Transcription of Smo 1 0.02 0.05 0.3
41 INT277474 Positive_regulation of Gene_expression of SMO 1 0.11 0 0.29
42 INT216120 Negative_regulation of SMO 2 0.49 3.05 0.27
43 INT297460 Regulation of Regulation of Ngfr 1 0.33 0.32 0.21
44 INT297459 Protein_catabolism of Ngfr 1 0.21 0.5 0.1
45 INT345344 Regulation of SMO 1 0.23 1.07 0.06
46 INT285151 Regulation of Localization of NGFR 1 0.02 0.24 0.05
47 INT262772 Binding of SMO 1 0.27 0.59 0.05
48 INT262777 Localization of SMO 1 0.59 0.6 0.04
49 INT241405 Localization of Ngfr 2 0.56 0.4 0.03
50 INT241402 Protein_catabolism of Ngfr 1 0.39 0 0.03
51 INT143428 Negative_regulation of Gene_expression of NGFR 1 0.57 0 0
52 INT252242 Gene_expression of Smo 1 0.01 0.23 0
53 INT193880 Regulation of Phosphorylation of Ngfr 1 0.02 0.25 0
54 INT201629 Negative_regulation of Positive_regulation of Ngfr 1 0.07 0.37 0
55 INT205956 Localization of Smo 1 0.06 0.71 0
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