GO:0051865

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Name protein autoubiquitination
Categary Process
Go Slim No
Go Link GO:0051865
Unique Molecular Interactions 121
Total Molecular Interactions 141
Total Single Events 539
Pain Genes Associated 19

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for protein autoubiquitination. They are ordered first by their pain relevance and then by number of times they were reported for protein autoubiquitination. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT51497 Cck Negative_regulation of Localization of Trim13 1 0.34 0 4.53
2 INT42727 Binding of Oprm1 and Trim13 1 0.14 0 2.54
3 INT57824 Binding of Trim13 and Slc25a2 1 0.01 0.08 1.19
4 INT20929 Binding of Trim13 and Vas1 1 0.10 0 1.18
5 INT57823 Binding of Trim13 and Atxn2l 1 0.00 0.08 1.17
6 INT12684 Binding of Bcar3 and Trim13 1 0.03 0 1.08
7 INT46540 TRIM13 Positive_regulation of GPANK1 1 0.05 0 0.83
8 INT72387 Trim13 Regulation of Phosphorylation of Shc1 1 0.32 0.09 0.54
9 INT339511 Binding of Tlr4 and Traf6 1 0.05 0.12 0.38
10 INT339512 Negative_regulation of Binding of Tlr4 and Traf6 1 0.05 0.17 0.38
11 INT339506 Binding of Irak1 and Traf6 1 0.03 0.12 0.37
12 INT353454 Binding of BRCA1 and IL17A 1 0.00 2.55 0.36
13 INT353452 Binding of AGRP and BRCA1 1 0.00 3.89 0.34
14 INT324690 Binding of Traf6 and Ticam1 2 0.07 0.23 0.33
15 INT203089 Binding of Il1a and Traf6 1 0.04 0.66 0.32
16 INT203086 Positive_regulation of Binding of Il1a and Traf6 1 0.06 0.67 0.32
17 INT323710 TRAF6 Regulation of MIR146A 1 0.06 0.55 0.28
18 INT353448 BRCA1 Positive_regulation of CCL2 1 0.01 1.37 0.26
19 INT353449 BRCA1 Positive_regulation of IL4 1 0.00 1.37 0.26
20 INT353455 BRCA1 Positive_regulation of IL13 1 0.00 1.37 0.26
21 INT243640 Binding of Twist1 and Stub1 1 0.08 0.34 0.24
22 INT223570 Binding of Mri1 and Uhrf2 1 0.02 0.56 0.22
23 INT301282 Tnfsf11 Positive_regulation of Traf6 1 0.10 0.65 0.2
24 INT190637 Negative_regulation of Binding of Rab7 and Rnf115 1 0.25 0.68 0.17
25 INT217478 Binding of Tnfrsf11a and Traf6 1 0.39 1.22 0.17
26 INT190630 Binding of Rab7 and Rnf115 1 0.22 0.68 0.17
27 INT188694 Traf6 Positive_regulation of Positive_regulation of Irf3 1 0.08 0.2 0.15
28 INT353451 Binding of BRCA1 and CRP 1 0.01 1.18 0.14
29 INT353453 Binding of BRCA1 and IL4 1 0.00 1.18 0.14
30 INT209645 AR Regulation of STUB1 1 0.04 0.93 0.13
31 INT334254 Binding of Traf6 and Gtf3a 1 0.00 0.18 0.11
32 INT217470 Traf6 Positive_regulation of Ngf 1 0.36 0.52 0.1
33 INT154711 Binding of SGCG and Rnf13 1 0.36 0.76 0.1
34 INT44591 PLAT Negative_regulation of CNOT4 1 0.10 0.33 0.1
35 INT217477 Traf6 Positive_regulation of Binding of Nup62 1 0.32 0.47 0.09
36 INT111866 Binding of LNPEP and CNOT4 1 0.02 0 0.09
37 INT251569 Binding of Ripk1 and Traf2 1 0.12 0.67 0.08
38 INT190636 Nr1h2 Positive_regulation of Rnf115 1 0.20 0.71 0.08
39 INT298258 Binding of Runx3 and Stub1 1 0.11 0.18 0.06
40 INT353450 Binding of BRCA1 and VEGFA 1 0.01 0.82 0.05
41 INT217471 Binding of Nup62 and Traf6 1 0.26 0 0.05
42 INT334265 Binding of Traf6 and Irak4 1 0.19 0.24 0.05
43 INT201729 Traf6 Positive_regulation of Phosphorylation of Nfkb1 1 0.00 0.45 0.04
44 INT201733 Traf6 Positive_regulation of Protein_catabolism of Nfkbib 1 0.00 0.44 0.04
45 INT190095 Negative_regulation of Binding of Hivep3 and Traf2 1 0.15 0.08 0.04
46 INT201750 Traf6 Positive_regulation of Cib1 1 0.00 0.37 0.04
47 INT210466 Negative_regulation of Binding of Gopc and Uhrf2 1 0.10 0.07 0.04
48 INT342726 Binding of Laptm5 and Park2 1 0.03 0.64 0.04
49 INT190096 Binding of Hivep3 and Traf2 1 0.17 0.08 0.04
50 INT210465 Binding of Gopc and Uhrf2 1 0.09 0.07 0.04
51 INT201746 Traf6 Positive_regulation of Map4k4 1 0.00 0.37 0.04
52 INT213815 Binding of Tfeb and Stub1 1 0.13 0.09 0.04
53 INT201739 Traf6 Positive_regulation of Localization of Nfkb1 1 0.00 0.45 0.04
54 INT348526 Binding of TRAF2 and EDAR 1 0.15 0.52 0.03
55 INT348538 Binding of TRAF2 and EDARADD 1 0.06 0.53 0.03
56 INT173199 CNOT4 Regulation of Regulation of Myc 1 0.01 0.66 0.03
57 INT221262 Binding of BRCA1 and CD4 1 0.22 0.81 0.03
58 INT234178 Binding of BRCA1 and BRCA2 2 0.40 1.52 0
59 INT292553 Binding of TRAF2 and TRADD 1 0.09 0.1 0
60 INT317301 Binding of Park2 and Park7 1 0.36 0.62 0
61 INT342725 Pink1 Positive_regulation of Phosphorylation of Park2 1 0.29 0.62 0
62 INT292560 Binding of TNFRSF1A and TRAF2 1 0.08 0.09 0
63 INT313117 Binding of Stub1 and Carf 1 0.10 0 0
64 INT234180 Binding of BRCA1 and BRIP1 1 0.33 1.37 0
65 INT314743 Binding of RAD51 and Brca1 1 0.06 1.06 0
66 INT348521 TRAF2 Positive_regulation of MAP3K1 1 0.03 0.46 0
67 INT314740 Binding of ESR1 and Brca1 1 0.16 0.69 0
68 INT317300 Binding of Park2 and Pink1 1 0.48 1.23 0
69 INT342727 Pink1 Positive_regulation of Park2 1 0.29 0.62 0
70 INT232595 Binding of BRCA1 and HEPACAM 1 0.02 0.89 0
71 INT348528 TRAF2 Positive_regulation of Positive_regulation of CASP8 1 0.02 0.44 0
72 INT317302 Binding of Park2 and Mul1 1 0.01 0.62 0
73 INT348020 Binding of Traf6 and Irak2 1 0.13 0.05 0
74 INT348037 Irak2 Positive_regulation of Binding of Traf6 1 0.18 0.05 0
75 INT283062 ERCC8 Positive_regulation of CFH 1 0.02 1.88 0
76 INT243635 Positive_regulation of Binding of Nfatc2 and Stub1 1 0.09 0 0
77 INT263588 SPIC Positive_regulation of TRIM21 1 0.00 0.28 0
78 INT259091 Binding of BRCA1 and LMO4 1 0.24 0.74 0
79 INT314745 Binding of TP53 and Brca1 1 0.18 1.17 0
80 INT222870 Traf2 Positive_regulation of Chuk 1 0.03 0.37 0
81 INT243628 Binding of Nfatc2 and Stub1 1 0.06 0 0
82 INT283061 Binding of ERCC8 and LDLR 1 0.00 0.44 0
83 INT296162 Mcph1 Regulation of Brca1 1 0.26 0.19 0
84 INT175193 NUP62 Regulation of Binding of TRAF6 1 0.07 0.06 0
85 INT175191 Binding of TRAF6 and NUP62 1 0.06 0.06 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for protein autoubiquitination. They are ordered first by their pain relevance and then by number of times they were reported in protein autoubiquitination. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT15102 Gene_expression of Trim13 18 0.67 0.43 15.49
2 INT1567 Binding of TRIM13 10 0.47 0.24 9.16
3 INT21438 Binding of Trim13 10 0.47 0.26 8.76
4 INT51494 Localization of Trim13 1 0.60 0 4.36
5 INT119063 Gene_expression of BRCA1 24 0.67 30.04 4.17
6 INT2677 Regulation of Trim13 3 0.44 0.5 3.91
7 INT51495 Positive_regulation of Trim13 3 0.41 0.08 3.81
8 INT24160 Gene_expression of TRIM13 7 0.65 1.42 3.46
9 INT221269 Binding of BRCA1 14 0.40 31.77 2.7
10 INT209889 Gene_expression of TRAF6 13 0.63 6.85 2.67
11 INT32923 Negative_regulation of Binding of TRIM13 2 0.57 0 2.38
12 INT30385 Protein_catabolism of Trim13 2 0.97 0 2.22
13 INT51496 Negative_regulation of Localization of Trim13 1 0.32 0 2.18
14 INT45064 Protein_catabolism of TRIM13 6 0.86 0 1.8
15 INT41820 Positive_regulation of TRIM13 3 0.49 0.46 1.65
16 INT66942 Negative_regulation of Protein_catabolism of Trim13 1 0.50 0 1.58
17 INT72377 Phosphorylation of Trim13 1 0.79 0.27 1.57
18 INT221422 Positive_regulation of BRCA1 5 0.23 12.63 1.53
19 INT119062 Negative_regulation of BRCA1 12 0.49 13.7 1.36
20 INT190067 Binding of Traf2 5 0.20 3.28 1.27
21 INT298979 Gene_expression of Traf6 5 0.31 1.75 1.21
22 INT60135 Negative_regulation of Protein_catabolism of TRIM13 1 0.30 0 1.1
23 INT46734 Positive_regulation of Stub1 6 0.16 1.44 1.09
24 INT223563 Gene_expression of Uhrf2 4 0.48 1.15 1.04
25 INT27314 Negative_regulation of CNOT4 4 0.00 1.64 0.98
26 INT60140 Localization of TRIM13 1 0.53 0 0.94
27 INT351587 Positive_regulation of Gene_expression of Uhrf2 1 0.29 0.81 0.92
28 INT156641 Positive_regulation of CNOT4 4 0.07 3.19 0.9
29 INT32948 Negative_regulation of Binding of Trim13 1 0.41 0 0.86
30 INT41819 Regulation of TRIM13 2 0.44 0.2 0.85
31 INT177387 Positive_regulation of TRAF2 3 0.26 1.44 0.84
32 INT29924 Negative_regulation of Gene_expression of Trim13 1 0.34 0 0.74
33 INT50855 Gene_expression of TRIM21 4 0.65 3.07 0.71
34 INT188799 Positive_regulation of Protein_catabolism of Traf6 2 0.19 1.98 0.62
35 INT112665 Gene_expression of TRAF2 3 0.29 3.97 0.61
36 INT196939 Gene_expression of Stub1 10 0.18 1.67 0.59
37 INT154745 Protein_catabolism of Traf2 1 0.86 1.04 0.59
38 INT154750 Positive_regulation of Protein_catabolism of Traf2 1 0.60 1.05 0.59
39 INT294555 Negative_regulation of Traf2 1 0.06 1.24 0.58
40 INT221420 Positive_regulation of Gene_expression of BRCA1 2 0.24 2.17 0.55
41 INT33731 Negative_regulation of TRIM13 1 0.41 0.26 0.55
42 INT214855 Regulation of Positive_regulation of CNOT4 1 0.02 0.66 0.53
43 INT190074 Positive_regulation of Traf2 1 0.19 0.37 0.52
44 INT72378 Positive_regulation of Phosphorylation of Trim13 1 0.49 0.08 0.51
45 INT315427 Positive_regulation of Uhrf2 2 0.38 0.33 0.5
46 INT89258 Localization of STUB1 3 0.14 0.67 0.49
47 INT209013 Regulation of Stub1 1 0.06 0.29 0.46
48 INT188800 Protein_catabolism of Traf6 2 0.40 1.6 0.45
49 INT154708 Gene_expression of Rnf13 1 0.67 3.27 0.45
50 INT343940 Binding of Uhrf2 2 0.30 0.06 0.42
51 INT209891 Regulation of Gene_expression of TRAF6 2 0.22 1.4 0.41
52 INT40183 Regulation of Binding of Trim13 1 0.44 0 0.41
53 INT156643 Positive_regulation of Positive_regulation of CNOT4 2 0.05 1.64 0.39
54 INT111872 Binding of CNOT4 4 0.02 1.11 0.37
55 INT217464 Binding of Traf6 5 0.29 1.28 0.35
56 INT353457 Positive_regulation of Binding of BRCA1 1 0.09 1.69 0.34
57 INT203075 Positive_regulation of Traf6 1 0.16 0.67 0.32
58 INT203074 Positive_regulation of Positive_regulation of Traf6 1 0.16 0.67 0.32
59 INT156647 Transcription of CNOT4 1 0.07 0.79 0.32
60 INT156650 Positive_regulation of Transcription of CNOT4 1 0.05 0.79 0.32
61 INT144854 Gene_expression of STUB1 10 0.13 2.03 0.31
62 INT221419 Regulation of BRCA1 5 0.35 6.18 0.31
63 INT209886 Positive_regulation of TRAF6 2 0.39 1.27 0.28
64 INT315428 Transcription of Uhrf2 1 0.38 0 0.28
65 INT118490 Regulation of CNOT4 2 0.02 1.18 0.27
66 INT144855 Positive_regulation of STUB1 3 0.08 0.59 0.26
67 INT323753 Negative_regulation of Gene_expression of TRAF6 1 0.21 0.52 0.26
68 INT44599 Gene_expression of CNOT4 4 0.40 3.09 0.25
69 INT210927 Positive_regulation of Traf6 4 0.32 0.99 0.22
70 INT154709 Positive_regulation of Gene_expression of Rnf13 1 0.35 1.65 0.22
71 INT203471 Localization of Stub1 1 0.23 0.5 0.21
72 INT323720 Negative_regulation of TRAF6 1 0.21 0.41 0.21
73 INT254173 Transcription of Traf6 1 0.25 0.26 0.21
74 INT343887 Positive_regulation of Gene_expression of TRAF6 1 0.16 0.21 0.19
75 INT221268 Localization of BRCA1 7 0.63 4.83 0.18
76 INT119061 Negative_regulation of Gene_expression of BRCA1 4 0.51 0.85 0.18
77 INT89689 Binding of Brca1 2 0.37 2.55 0.18
78 INT252702 Binding of TRAF2 3 0.23 2.21 0.16
79 INT315429 Regulation of Uhrf2 1 0.32 0 0.16
80 INT134909 Positive_regulation of TRIM21 1 0.67 0.95 0.16
81 INT154744 Regulation of Protein_catabolism of Traf2 1 0.39 0.18 0.16
82 INT190581 Gene_expression of Rnf115 1 0.51 0.65 0.15
83 INT188688 Regulation of Traf6 1 0.24 0.15 0.15
84 INT323747 Regulation of TRAF6 1 0.13 1.15 0.14
85 INT251559 Binding of Traf2 1 0.23 1.68 0.13
86 INT323728 Phosphorylation of TRAF6 1 0.39 0.79 0.12
87 INT187590 Gene_expression of Brca1 12 0.65 4.94 0.11
88 INT208914 Regulation of Brca1 1 0.10 0.79 0.11
89 INT251560 Positive_regulation of Traf2 1 0.13 0.47 0.09
90 INT184167 Binding of STUB1 5 0.07 0.72 0.08
91 INT243617 Binding of Stub1 3 0.09 0.16 0.08
92 INT175210 Binding of TRAF6 2 0.17 0.73 0.08
93 INT342696 Gene_expression of Park2 1 0.65 1.19 0.08
94 INT174155 Negative_regulation of Brca1 4 0.36 1.77 0.07
95 INT315425 Negative_regulation of Uhrf2 2 0.34 0.21 0.07
96 INT44603 Negative_regulation of Gene_expression of CNOT4 1 0.30 0.24 0.06
97 INT223566 Localization of Uhrf2 1 0.32 0.07 0.05
98 INT317299 Binding of Park2 1 0.36 0.61 0.04
99 INT351586 Negative_regulation of Gene_expression of Uhrf2 1 0.25 0 0.04
100 INT187589 Positive_regulation of Gene_expression of Brca1 2 0.55 1.93 0.03
101 INT344009 Negative_regulation of Localization of BRCA1 1 0.30 0.18 0.03
102 INT182999 Negative_regulation of Gene_expression of STUB1 1 0.08 0.31 0.03
103 INT233105 Localization of CNOT4 1 0.11 0.71 0.03
104 INT259116 Transcription of BRCA1 3 0.44 3.77 0
105 INT79864 Positive_regulation of Protein_catabolism of TRIM13 2 0.31 0 0
106 INT200277 Positive_regulation of Gene_expression of Stub1 2 0.06 0 0
107 INT196230 Regulation of STUB1 2 0.05 0.8 0
108 INT212457 Phosphorylation of Brca1 2 0.51 0.96 0
109 INT342695 Phosphorylation of Park2 1 0.79 0.62 0
110 INT209699 Negative_regulation of STUB1 1 0.07 0.41 0
111 INT187580 Positive_regulation of Brca1 1 0.10 1.17 0
112 INT263602 Negative_regulation of TRIM21 1 0.01 0.28 0
113 INT119064 Regulation of Gene_expression of BRCA1 1 0.53 0.05 0
114 INT354311 Positive_regulation of Binding of CNOT4 1 0.01 0.39 0
115 INT342089 Regulation of Gene_expression of Stub1 1 0.02 0.16 0
116 INT298986 Positive_regulation of Gene_expression of Traf6 1 0.23 0.4 0
117 INT222849 Gene_expression of Traf2 1 0.12 0.38 0
118 INT314706 Transcription of Brca1 1 0.43 0.53 0
119 INT221271 Negative_regulation of Binding of BRCA1 1 0.28 0.93 0
120 INT298982 Positive_regulation of Positive_regulation of Traf6 1 0.23 0.4 0
121 INT252712 Phosphorylation of TRAF2 1 0.28 1.38 0
122 INT348474 Regulation of Gene_expression of TRAF2 1 0.23 0.41 0
123 INT313091 Negative_regulation of Stub1 1 0.07 0.25 0
124 INT150198 Gene_expression of ERCC8 1 0.09 0.12 0
125 INT334189 Regulation of Binding of BRCA1 1 0.13 0.8 0
126 INT234188 Positive_regulation of Localization of BRCA1 1 0.42 0.68 0
127 INT150197 Regulation of ERCC8 1 0.03 0.13 0
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