GO:0051893

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Name regulation of focal adhesion assembly
Categary Process
Go Slim No
Go Link GO:0051893
Unique Molecular Interactions 71
Total Molecular Interactions 98
Total Single Events 653
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for regulation of focal adhesion assembly. They are ordered first by their pain relevance and then by number of times they were reported for regulation of focal adhesion assembly. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT116930 OPRK1 Positive_regulation of Binding of PTK2 1 0.28 0.35 0.93
2 INT116109 VEGFA Positive_regulation of PTK2 1 0.13 0.3 0.83
3 INT111936 Binding of PIK3CA and PTK2 1 0.19 0.67 0.65
4 INT111937 Binding of PIK3CG and PTK2 1 0.08 0.67 0.64
5 INT116932 PTK2 Negative_regulation of Positive_regulation of MAPK8 1 0.35 0.17 0.48
6 INT116935 Positive_regulation of OPRK1 Positive_regulation of Phosphorylation of PTK2 1 0.39 0.17 0.47
7 INT116939 OPRK1 Positive_regulation of Phosphorylation of PTK2 1 0.39 0.17 0.46
8 INT116928 PTK2 Positive_regulation of JUN 1 0.20 0.15 0.46
9 INT183645 Ppp1r14b Positive_regulation of Macf1 1 0.00 1.23 0.38
10 INT183647 Dss1 Positive_regulation of Macf1 1 0.01 1.23 0.38
11 INT183646 Negative_regulation of Ppp1r14b Positive_regulation of Macf1 1 0.00 1.29 0.38
12 INT193031 CHRM2 Positive_regulation of ROCK1 1 0.00 0.12 0.24
13 INT283858 Binding of PTK2 and APOA5 1 0.00 0.67 0.21
14 INT183644 Nos2 Positive_regulation of Gene_expression of Macf1 1 0.05 0.84 0.21
15 INT178086 Binding of EDNRA and PTK2 1 0.07 0.82 0.2
16 INT343547 ROCK1 Positive_regulation of Gene_expression of PTHLH 1 0.15 0.2 0.2
17 INT269446 Binding of EPHA3 and HHIP 1 0.01 0 0.2
18 INT193080 ROCK1 Positive_regulation of Ppp1r14a 1 0.00 0.13 0.18
19 INT178092 EDN3 Positive_regulation of PTK2 1 0.01 1.02 0.17
20 INT178073 EDN1 Positive_regulation of PTK2 1 0.03 1.02 0.17
21 INT147727 Phosphorylation of PTK2 Regulation of Positive_regulation of RAC1 1 0.34 0.32 0.14
22 INT147726 Phosphorylation of PTK2 Regulation of Positive_regulation of PIK3CA 1 0.09 0.32 0.14
23 INT343542 ROCK1 Positive_regulation of Positive_regulation of PTHLH 1 0.21 0 0.12
24 INT178089 Binding of EDNRA and Positive_regulation of PTK2 1 0.09 0.74 0.09
25 INT355582 VEGFA Regulation of Positive_regulation of PTK2 1 0.05 1.46 0.08
26 INT272003 Binding of Tsc2 and Tsc1 1 0.18 1.1 0.07
27 INT346280 Binding of COL5A2 and PTK2 1 0.01 0.1 0.05
28 INT246793 Binding of Tsc2 and Tsc1 1 0.04 0.71 0.04
29 INT269584 Binding of CFL1 and ROCK1 1 0.03 0.05 0.03
30 INT343546 Negative_regulation of ROCK1 Negative_regulation of Gene_expression of PTHLH 1 0.16 3.28 0.03
31 INT343545 Binding of GLI2 and ROCK1 1 0.07 0.65 0.03
32 INT272009 Binding of YWHAQ and Tsc1 1 0.37 0.14 0.03
33 INT343537 ROCK1 Regulation of Gene_expression of PTHLH 1 0.08 0.09 0.03
34 INT292464 Binding of PTK2 and MMRN1 1 0.03 0.26 0
35 INT292505 PTK2 Regulation of Birc5 1 0.29 0.76 0
36 INT292444 BAD Positive_regulation of Phosphorylation of PTK2 1 0.13 0.9 0
37 INT292463 LAMB2 Positive_regulation of Phosphorylation of PTK2 1 0.01 0.7 0
38 INT199365 Igf2 Positive_regulation of Phosphorylation of Macf1 1 0.13 1.84 0
39 INT199359 Igf2 Regulation of Macf1 1 0.11 3.11 0
40 INT246808 Tsc2 Regulation of Regulation of Tsc1 1 0.02 0.05 0
41 INT258209 ROCK1 Regulation of ARR3 1 0.00 0.2 0
42 INT199361 Regulation of Igf2 Regulation of Macf1 1 0.11 1.59 0
43 INT271990 Tsc1 Positive_regulation of Tsc2 1 0.36 0.31 0
44 INT331222 Tsc1 Negative_regulation of Mtor 1 0.00 0.68 0
45 INT271996 Binding of Plk1 and Tsc1 1 0.09 0.32 0
46 INT292497 Mlph Positive_regulation of Phosphorylation of PTK2 1 0.05 7.24 0
47 INT258202 ROCK1 Positive_regulation of MYL2 1 0.14 0.2 0
48 INT292498 Mlph Regulation of Phosphorylation of PTK2 1 0.02 0.33 0
49 INT271991 Tsc1 Regulation of Tsc2 1 0.23 0.15 0
50 INT292452 Gene_expression of PTK2 Negative_regulation of Positive_regulation of AKT1 1 0.14 0.6 0
51 INT272017 TBC1D7 Positive_regulation of Protein_catabolism of Tsc1 1 0.08 0.46 0
52 INT292453 PTK2 Regulation of Gene_expression of GEM 1 0.16 0.42 0
53 INT283863 Binding of MAPK1 and PTK2 1 0.12 0.97 0
54 INT199366 DST Positive_regulation of Macf1 1 0.01 1.14 0
55 INT271985 Tsc1 Regulation of Cdkn1b 1 0.04 0.1 0
56 INT272008 Tsc1 Negative_regulation of Binding of HERC1 1 0.01 0.32 0
57 INT292495 Mlph Regulation of Gene_expression of PTK2 1 0.03 0.21 0
58 INT292461 PTK2 Regulation of BCL2 1 0.02 0.76 0
59 INT272014 Binding of RB1CC1 and Tsc1 1 0.05 0.44 0
60 INT292451 PTK2 Regulation of BAX 1 0.02 0.76 0
61 INT331223 Negative_regulation of Tsc1 Positive_regulation of Positive_regulation of Mtor 1 0.01 0.33 0
62 INT269562 GOPC Positive_regulation of Gene_expression of EPHA3 1 0.03 0 0
63 INT292448 Positive_regulation of PTK2 Positive_regulation of Phosphorylation of AKT1 1 0.15 0.28 0
64 INT292457 PTK2 Regulation of BAD 1 0.03 0.76 0
65 INT292506 Mlph Regulation of PTK2 1 0.01 0.21 0
66 INT261730 ROCK1 Positive_regulation of Positive_regulation of F2R 1 0.37 0 0
67 INT271998 Cdk1 Positive_regulation of Phosphorylation of Tsc1 1 0.17 0.3 0
68 INT292460 GEM Positive_regulation of Phosphorylation of PTK2 1 0.20 0.52 0
69 INT271986 Tsc1 Regulation of Skp2 1 0.13 0.14 0
70 INT199362 Igf2 Positive_regulation of Macf1 1 0.11 1.67 0
71 INT331221 Binding of Akt1 and Tsc1 1 0.03 0.33 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for regulation of focal adhesion assembly. They are ordered first by their pain relevance and then by number of times they were reported in regulation of focal adhesion assembly. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT60161 Gene_expression of EPHA3 43 0.75 3.66 6.25
2 INT87345 Phosphorylation of PTK2 110 0.82 59.39 4.28
3 INT269377 Positive_regulation of EPHA3 22 0.18 0.97 2.55
4 INT116110 Positive_regulation of PTK2 20 0.66 10.53 1.64
5 INT111946 Positive_regulation of Phosphorylation of PTK2 8 0.66 11.5 1.53
6 INT168312 Positive_regulation of Gene_expression of EPHA3 8 0.49 0.97 1.32
7 INT87343 Negative_regulation of Phosphorylation of PTK2 34 0.59 18.38 1.19
8 INT87346 Binding of PTK2 6 0.37 4.03 1.18
9 INT126534 Negative_regulation of ROCK1 18 0.49 14.32 1.13
10 INT87342 Regulation of Phosphorylation of PTK2 3 0.59 5.7 1.05
11 INT87344 Gene_expression of PTK2 90 0.78 59.03 0.87
12 INT269642 Binding of EPHA3 4 0.10 0.22 0.8
13 INT87341 Regulation of Gene_expression of PTK2 2 0.62 8.34 0.77
14 INT271939 Regulation of Tsc1 2 0.41 1.16 0.47
15 INT269613 Negative_regulation of Binding of EPHA3 2 0.11 0.27 0.43
16 INT16932 Localization of EPHA3 3 0.73 0.15 0.38
17 INT183634 Positive_regulation of Macf1 2 0.13 6.25 0.38
18 INT185436 Gene_expression of ROCK1 5 0.52 6.85 0.29
19 INT322756 Negative_regulation of Tsc1 1 0.07 1.4 0.26
20 INT119080 Negative_regulation of PTK2 15 0.56 8.88 0.23
21 INT258250 Positive_regulation of ROCK1 7 0.51 2.07 0.22
22 INT87338 Regulation of PTK2 10 0.62 4.75 0.21
23 INT185443 Regulation of ROCK1 4 0.18 3.32 0.21
24 INT292483 Negative_regulation of Positive_regulation of PTK2 2 0.41 3.51 0.18
25 INT183631 Gene_expression of Macf1 2 0.13 5.64 0.18
26 INT147730 Regulation of Positive_regulation of PTK2 1 0.35 0.33 0.15
27 INT269628 Regulation of EPHA3 2 0.12 0.2 0.12
28 INT147735 Regulation of Binding of PTK2 1 0.35 0.23 0.08
29 INT271938 Binding of Tsc1 1 0.43 3.18 0.07
30 INT144400 Positive_regulation of Gene_expression of PTK2 33 0.70 21.24 0.06
31 INT199335 Negative_regulation of Macf1 1 0.11 9.66 0.06
32 INT329775 Regulation of Regulation of PTK2 1 0.11 0.49 0.05
33 INT269400 Positive_regulation of Phosphorylation of EPHA3 1 0.11 0.05 0.05
34 INT341887 Positive_regulation of Positive_regulation of ROCK1 1 0.01 0.12 0.05
35 INT271914 Negative_regulation of Tsc1 5 0.38 3.08 0.04
36 INT269388 Phosphorylation of EPHA3 3 0.21 0.16 0.04
37 INT343555 Regulation of Gene_expression of ROCK1 1 0.15 1.02 0.04
38 INT271930 Gene_expression of Tsc1 1 0.69 6.88 0.04
39 INT246758 Gene_expression of Tsc1 1 0.11 0.55 0.04
40 INT192237 Phosphorylation of ROCK1 2 0.19 0.39 0.03
41 INT269599 Negative_regulation of Positive_regulation of EPHA3 1 0.11 0.47 0.03
42 INT269649 Positive_regulation of Localization of EPHA3 1 0.13 0 0.03
43 INT343556 Positive_regulation of Gene_expression of ROCK1 1 0.23 1.05 0.03
44 INT269618 Negative_regulation of Localization of EPHA3 1 0.11 0 0.03
45 INT292474 Negative_regulation of Gene_expression of PTK2 8 0.41 5.17 0
46 INT271936 Phosphorylation of Tsc1 4 0.73 1.76 0
47 INT262779 Localization of PTK2 3 0.71 2.75 0
48 INT181035 Binding of Macf1 2 0.26 1.61 0
49 INT199351 Phosphorylation of Macf1 1 0.18 3.61 0
50 INT269651 Positive_regulation of Phosphorylation of ROCK1 1 0.11 0.29 0
51 INT258237 Negative_regulation of Negative_regulation of ROCK1 1 0.32 0.16 0
52 INT246748 Regulation of Tsc1 1 0.04 0.05 0
53 INT292478 Negative_regulation of Negative_regulation of PTK2 1 0.41 0.97 0
54 INT199338 Localization of Macf1 1 0.14 1.98 0
55 INT329769 Positive_regulation of Localization of PTK2 1 0.17 1.42 0
56 INT269607 Regulation of Positive_regulation of EPHA3 1 0.12 0 0
57 INT199339 Negative_regulation of Positive_regulation of Macf1 1 0.09 1.4 0
58 INT199350 Positive_regulation of Negative_regulation of Macf1 1 0.10 3.9 0
59 INT269634 Positive_regulation of Positive_regulation of EPHA3 1 0.18 0 0
60 INT246773 Phosphorylation of Tsc1 1 0.13 0.05 0
61 INT269626 Negative_regulation of Phosphorylation of EPHA3 1 0.11 0.11 0
62 INT269667 Regulation of Phosphorylation of EPHA3 1 0.12 0.11 0
63 INT271913 Protein_catabolism of Tsc1 1 0.51 0.45 0
64 INT271906 Negative_regulation of Binding of Tsc1 1 0.38 0.06 0
65 INT199331 Positive_regulation of Positive_regulation of Macf1 1 0.10 1.69 0
66 INT199346 Negative_regulation of Negative_regulation of Macf1 1 0.08 1.92 0
67 INT271927 Positive_regulation of Tsc1 1 0.44 0.4 0
68 INT271931 Negative_regulation of Gene_expression of Tsc1 1 0.38 0.44 0
69 INT269633 Regulation of Localization of EPHA3 1 0.12 0 0
70 INT331195 Positive_regulation of Negative_regulation of Tsc1 1 0.18 0.15 0
71 INT199352 Negative_regulation of Localization of Macf1 1 0.08 1.98 0
72 INT292481 Negative_regulation of Localization of PTK2 1 0.41 0.07 0
73 INT269645 Negative_regulation of Positive_regulation of ROCK1 1 0.10 0 0
74 INT246757 Binding of Tsc1 1 0.06 0.19 0
75 INT269612 Negative_regulation of EPHA3 1 0.11 0.17 0
76 INT329766 Positive_regulation of Positive_regulation of PTK2 1 0.11 0.51 0
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